OOIR: Observatory of International Research

Papers

(The H4-Index of Acta Neuropathologica is 40. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Regulated cell death and its role in Alzheimer’s disease and amyotrophic lateral sclerosis	146
HnRNP K mislocalisation is a novel protein pathology of frontotemporal lobar degeneration and ageing and leads to cryptic splicing	132
Transcriptome analysis stratifies second-generation non-WNT/non-SHH medulloblastoma subgroups into clinically tractable subtypes	127
Alternatively spliced ELAVL3 cryptic exon 4a causes ELAVL3 downregulation in ALS TDP-43 proteinopathy	113
Blood-based Aβ42 increases in the earliest pre-pathological stage before decreasing with progressive amyloid pathology in preclinical models and human subjects: opening new avenues for prevention	111
Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas are associated with a predominance in proliferating and progenitor-like cell subpopulations	109
Tau seeds occur before earliest Alzheimer’s changes and are prevalent across neurodegenerative diseases	106
Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice	103
Abundant transcriptomic alterations in the human cerebellum of patients with a C9orf72 repeat expansion	99
Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE	99
A novel subtype of sporadic Creutzfeldt–Jakob disease with PRNP codon 129MM genotype and PrP plaques	90
Correction to: Accumulation of TMEM106B C‑terminal fragments in neurodegenerative disease and aging	80
Capillary basement membrane reduplication in myositis patients with mild clinical features of systemic sclerosis supports the concept of ‘scleromyositis’	79
TMEM106B coding variant is protective and deletion detrimental in a mouse model of tauopathy	76
Increased NF-L levels in the TDP-43G298S ALS mouse model resemble NF-L levels in ALS patients	72
A glutaminyl cyclase-catalyzed α-synuclein modification identified in human synucleinopathies	71
Dominant-acting CSF1R variants cause microglial depletion and altered astrocytic phenotype in zebrafish and adult-onset leukodystrophy	70
Correction to: Flow blockage disrupts cilia-driven fluid transport in the epileptic brain	68
The proteomic landscape of glioblastoma recurrence reveals novel and targetable immunoregulatory drivers	65
Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis	64
Single-nucleus chromatin accessibility profiling highlights distinct astrocyte signatures in progressive supranuclear palsy and corticobasal degeneration	62
Correction to: Integrative proteomics highlight presynaptic alterations and c-Jun misactivation as convergent pathomechanisms in ALS	56
IL-10-providing B cells govern pro-inflammatory activity of macrophages and microglia in CNS autoimmunity	56
Somatic mosaic SOX10 indel mutations underlie a form of segmental schwannomatosis	55
Strain diversity in neurodegenerative disease: an argument for a personalized medicine approach to diagnosis and treatment	51

EZHIP: a new piece of the puzzle towards understanding pediatric posterior fossa ependymoma	51
Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling	51
AR cooperates with SMAD4 to maintain skeletal muscle homeostasis	50
Perivascular space dilation is associated with vascular amyloid-β accumulation in the overlying cortex	50
From shape to contents: heterogeneity of CNS glial cells	50
Pituitary neuroendocrine tumors with PIT1/SF1 co-expression show distinct clinicopathological and molecular features	49
Pineal parenchymal tumors of intermediate differentiation: in need of a stringent definition to avoid confusion. Scientific commentary on ‘Genetical and epigenetical profiling identifies two subgroups	49
The prevalence and topography of spinal cord demyelination in multiple sclerosis: a retrospective study	48
More than a co-incidence? Comment on: Amyotrophic lateral sclerosis is over‐represented in two Huntington’s disease brain bank cohorts: further evidence to support genetic pleiotropy of pathogenic HTT	48
AMFR dysfunction causes autosomal recessive spastic paraplegia in human that is amenable to statin treatment in a preclinical model	46
Persistent virus-specific and clonally expanded antibody-secreting cells respond to induced self-antigen in the CNS	43
Macrophages and endothelial cells in the neurovascular unit	42
Gene transcript fusions are associated with clinical outcomes and molecular groups of meningiomas	42
Co-registration of MALDI-MSI and histology demonstrates gangliosides co-localize with amyloid beta plaques in Alzheimer’s disease	41
Impaired GABAergic regulation and developmental immaturity in interneurons derived from the medial ganglionic eminence in the tuberous sclerosis complex	41
Comprehensive assessment of TDP-43 neuropathology data in the National Alzheimer’s Coordinating Center database	40
Regional AT-8 reactive tau species correlate with intracellular Aβ levels in cases of low AD neuropathologic change	40