Age and Ageing

Article	Citations
Prevalence of frailty in 62 countries across the world: a systematic review and meta-analysis of population-level studies	336
World guidelines for falls prevention and management for older adults: a global initiative	280
Ageism and COVID-19: what does our society’s response say about us?	237
Efficacy and safety of COVID-19 vaccines in older people	222
COVID-19 in older people: a rapid clinical review	164
Commentary: COVID in care homes—challenges and dilemmas in healthcare delivery	152
The COVID-19 rehabilitation pandemic	125
Delirium: a missing piece in the COVID-19 pandemic puzzle	112
Age and frailty are independently associated with increased COVID-19 mortality and increased care needs in survivors: results of an international multi-centre study	99
Diagnostic accuracy of the 4AT for delirium detection in older adults: systematic review and meta-analysis	97
Association of frailty with mortality in older inpatients with Covid-19: a cohort study	97
STOPPFall (Screening Tool of Older Persons Prescriptions in older adults with high fall risk): a Delphi study by the EuGMS Task and Finish Group on Fall-Risk-Increasing Drugs	91
What is the prevalence of loneliness amongst older people living in residential and nursing care homes? A systematic review and meta-analysis	90
Research with older people in a world with COVID-19: identification of current and future priorities, challenges and opportunities	87
Mild Cognitive Impairment: the Manchester consensus	85
The role of illness acuity on the association between frailty and mortality in emergency department patients referred to internal medicine	81
Sarcopenia definition, diagnosis and treatment: consensus is growing	81
Abdominal obesity, body mass index and the risk of frailty in community-dwelling older adults: a systematic review and meta-analysis	80
Probable delirium is a presenting symptom of COVID-19 in frail, older adults: a cohort study of 322 hospitalised and 535 community-based older adults	72
Resistance exercise as a treatment for sarcopenia: prescription and delivery	72
Effect of the COVID-19 lockdown on disease recognition and utilisation of healthcare services in the older population in Germany: a cross-sectional study	70
Comparing associations between frailty and mortality in hospitalised older adults with or without COVID-19 infection: a retrospective observational study using electronic health records	69
Frailty is associated with in-hospital mortality in older hospitalised COVID-19 patients in the Netherlands: the COVID-OLD study	69
Frailty, a multisystem ageing syndrome	68
Prevention of adverse drug reactions in hospitalized older patients with multi-morbidity and polypharmacy: the SENATOR* randomized controlled clinical trial	68

Deprescribing in older people approaching end-of-life: development and validation of STOPPFrail version 2	66
Clinical profile and predictors of in-hospital mortality among older patients hospitalised for COVID-19	66
Social isolation, loneliness and functional disability in Chinese older women and men: a longitudinal study	66
A classification tree to assist with routine scoring of the Clinical Frailty Scale	65
The impact of delirium on outcomes for older adults hospitalised with COVID-19	64
Virtual geriatric clinics and the COVID-19 catalyst: a rapid review	63
Weight-adjusted waist index reflects fat and muscle mass in the opposite direction in older adults	61
Frailty in the face of COVID-19	61
Prevalence, incidence and mortality of delirium in patients with COVID-19: a systematic review and meta-analysis	57
Poor oral hygiene, oral microorganisms and aspiration pneumonia risk in older people in residential aged care: a systematic review	57
Interventions to reduce falls in hospitals: a systematic review and meta-analysis	56
Anticholinergic drugs and incident dementia, mild cognitive impairment and cognitive decline: a meta-analysis	56
‘Getting back to normality seems as big of a step as going into lockdown’: the impact of the COVID-19 pandemic on people with early to middle stage dementia	51
Recurrent delirium over 12 months predicts dementia: results of the Delirium and Cognitive Impact in Dementia (DECIDE) study	49
New horizons in falls prevention and management for older adults: a global initiative	48
Life in lockdown: a telephone survey to investigate the impact of COVID-19 lockdown measures on the lives of older people (≥75 years)	47
Effects of dance on cognitive function in older adults: a systematic review and meta-analysis	46
Multimorbidity patterns and risk of frailty in older community-dwelling adults: a population-based cohort study	45
The prevalence and impact of potentially inappropriate prescribing among older persons in primary care settings: multilevel meta-analysis	45
Older patients undergoing emergency laparotomy: observations from the National Emergency Laparotomy Audit (NELA) years 1–4	44
The impact of COVID-19 on adjusted mortality risk in care homes for older adults in Wales, UK: a retrospective population-based cohort study for mortality in 2016–2020	43
Changes in psychological distress before and during the COVID-19 pandemic among older adults: the contribution of frailty transitions and multimorbidity	42
The UN Decade of healthy ageing: strengthening measurement for monitoring health and wellbeing of older people	41
Social isolation and loneliness as related to progression and reversion of frailty in the Survey of Health Aging Retirement in Europe (SHARE)	40
Comprehensive geriatric assessment in older people: an umbrella review of health outcomes	40
Scoping study of definitions of social participation: update and co-construction of an interdisciplinary consensual definition	40
Atrial fibrillation and oral anticoagulation in older people with frailty: a nationwide primary care electronic health records cohort study	40
SEeking AnsweRs for Care Homes during the COVID-19 pandemic (COVID SEARCH)	38
In-hospital adverse drug reactions in older adults; prevalence, presentation and associated drugs—a systematic review and meta-analysis	37
COVID-19 infection and attributable mortality in UK care homes: cohort study using active surveillance and electronic records (March–June 2020)	36
Does vascular endothelial dysfunction play a role in physical frailty and sarcopenia? A systematic review	36
The clinical usefulness of muscle mass and strength measures in older people: a systematic review	36
The effectiveness and cost-effectiveness of assistive technology and telecare for independent living in dementia: a randomised controlled trial	35
Association between multimorbidity and hospitalization in older adults: systematic review and meta-analysis	35
Mortality risk associated with combinations of loneliness and social isolation. Findings from The Irish Longitudinal Study on Ageing (TILDA)	34
What is the relationship between validated frailty scores and mortality for adults with COVID-19 in acute hospital care? A systematic review	34
The Clinical Frailty Scale predicts adverse outcome in older people admitted to a UK major trauma centre	33
Dual decline in gait speed and cognition is associated with future dementia: evidence for a phenotype	33
Frailty status predicts futility of cardiopulmonary resuscitation in older adults	33
Trajectories of depressive symptoms and subsequent cognitive decline in older adults: a pooled analysis of two longitudinal cohorts	32
The association of weight change and all-cause mortality in older adults: a systematic review and meta-analysis	32
The effect of multimorbidity on functional limitations and depression amongst middle-aged and older population in China: a nationwide longitudinal study	32
Rationing care by frailty during the COVID-19 pandemic	32
Is comprehensive geriatric assessment hospital at home a cost-effective alternative to hospital admission for older people?	32
The impact of health QR code system on older people in China during the COVID-19 outbreak	31
Prevalence and implications of frailty in acute stroke: systematic review & meta-analysis	31
Diabetes duration and the risk of dementia: a cohort study based on German health claims data	31
Clinical trials in older people	31
Factors associated with virtual care access in older adults: a cross-sectional study	31
Association between kidney function and incidence of dementia: 10-year follow-up of the Whitehall II cohort study	30

Care homes and COVID-19 in Hong Kong: how the lessons from SARS were used to good effect	29
Asymptomatic carriage rates and case fatality of SARS-CoV-2 infection in residents and staff in Irish nursing homes	29
Discharge after hip fracture surgery by mobilisation timing: secondary analysis of the UK National Hip Fracture Database	29
Potentially inappropriate prescribing in dementia, multi-morbidity and incidence of adverse health outcomes	29
Telomere length and its relationships with lifestyle and behavioural factors: variations by sex and race/ethnicity	29
The work of older people and their informal caregivers in managing an acute health event in a hospital at home or hospital inpatient setting	28
The effect of ageing on presentation, management and outcomes in degenerative cervical myelopathy: a systematic review	28
How do we define and measure sarcopenia? A meta-analysis of observational studies	27
Frailty: understanding the difference between age and ageing	27
Retinal photograph-based deep learning predicts biological age, and stratifies morbidity and mortality risk	27
Changes in health and functioning of care home residents over two decades: what can we learn from population-based studies?	27
Frailty among middle-aged and older Canadians: population norms for the frailty index using the Canadian Longitudinal Study on Aging	27
The demography and characteristics of SARS-CoV-2 seropositive residents and staff of nursing homes for older adults in the Community of Madrid: the SeroSOS study	27
Neutrophil-to-lymphocyte ratio predicts delirium after stroke	27
External validation of the Hospital Frailty Risk Score in France	26
Effectiveness of virtual reality technology on functional mobility of older adults: systematic review and meta-analysis	26
Perceptions, knowledge and attitudes about COVID-19 vaccine hesitancy in older Portuguese adults	26
Venous thromboembolic events in patients with COVID-19: a systematic review and meta-analysis	26
Epidemiology and impact of frailty in patients with atrial fibrillation in Europe	26
Contextual factors influencing complex intervention research processes in care homes: a systematic review and framework synthesis	25
A fuller picture of COVID-19 prognosis: the added value of vulnerability measures to predict mortality in hospitalised older adults	25
Attracting, recruiting and retaining nurses and care workers working in care homes: the need for a nuanced understanding informed by evidence and theory	24
Dynapenia, abdominal obesity or both: which accelerates the gait speed decline most?	24
Protective or harmful? A qualitative exploration of older people’s perceptions of worries about falling	24
Cognitive training interventions and depression in mild cognitive impairment and dementia: a systematic review and meta-analysis of randomized controlled trials	23
Retinal age gap as a predictive biomarker of future risk of Parkinson’s disease	23
Frailty is an outcome predictor in patients with acute ischemic stroke receiving endovascular treatment	22
Inflammaging as a target for healthy ageing	22
Barriers and facilitators to virtual care in a geriatric medicine clinic: a semi-structured interview study of patient, caregiver and healthcare provider perspectives	22
Changes in muscle strength and physical function in older patients during and after hospitalisation: a prospective repeated-measures cohort study	22
‘We have become prisoners of our own age’: from a continuing care retirement community to a total institution in the midst of the COVID-19 outbreak	22
A comparison of two national frailty scoring systems	21
Reasons for discontinuing oral anticoagulation therapy for atrial fibrillation: a systematic review	21
Epidemiology of COVID-19 in older persons, Wuhan, China	21
Development and validation of a model for predicting mortality in patients with hip fracture	21
Relationship between sarcopenia and orthostatic hypotension	21
European Working Group on Sarcopenia in Older People 2010 (EWGSOP1) and 2019 (EWGSOP2) criteria or slowness: which is the best predictor of mortality risk in older adults?	21
Neighbourhood walkability and physical activity: moderating role of a physical activity intervention in overweight and obese older adults with metabolic syndrome	21
Effects of an intervention to reduce fear of falling and increase physical activity during hip and pelvic fracture rehabilitation	20
Comparative effectiveness of non-pharmacological interventions for frailty: a systematic review and network meta-analysis	20
Effects of gait adaptability training on falls and fall-related fractures in older adults: a systematic review and meta-analysis	20
Magnitude, change over time, demographic characteristics and geographic distribution of excess deaths among nursing home residents during the first wave of COVID-19 in France: a nationwide cohort stud	20
Enhanced lateral flow testing strategies in care homes are associated with poor adherence and were insufficient to prevent COVID-19 outbreaks: results from a mixed methods implementation study	20
Associations between inflammation, cardiovascular biomarkers and incident frailty: the British Regional Heart Study	20
Frailty is associated with long-term outcome in patients with sepsis who are over 80 years old: results from an observational study in 241 European ICUs	20
Impact of COVID-19 restrictions on carers of persons with dementia in the UK: a qualitative study	20
Frailty and stroke thrombectomy outcomes—an observational cohort study	20
Why is living alone in older age related to increased mortality risk? A longitudinal cohort study	19
Care-home outbreaks of COVID-19 in Scotland March to May 2020: National linked data cohort analysis	19
Fall prevention in older people: past, present and future	19
Sexual satisfaction of middle-aged and older adults: longitudinal findings from a nationally representative sample	19
Impact of place of residence, frailty and other factors on rehabilitation outcomes post hip fracture	19
Cholesterol profiles and incident cognitive decline among older adults: the Shanghai Aging Study	19
How quality improvement collaboratives work to improve healthcare in care homes: a realist evaluation	19
Relationship between Fried’s frailty phenotype and oral frailty in long-term care residents	19
Follow-up of a Wuqinxi exercise at home programme to reduce pain and improve function for knee osteoarthritis in older people: a randomised controlled trial	19
A rapid point-of-care ultrasound marker for muscle mass and muscle strength in older adults	18
Rapid review of decision-making for place of care and death in older people: lessons for COVID-19	18
Impact of pain on reactive balance and falls in community-dwelling older adults: a prospective cohort study	18
Association of rhythm control with incident dementia among patients with atrial fibrillation: a nationwide population-based cohort study	18
COVID-19 testing in English care homes and implications for staff and residents	18
Diagnostic accuracy of dementia screening tools in the Chinese population: a systematic review and meta-analysis of 167 diagnostic studies	18
Computer-generated STOPP/START recommendations for hospitalised older adults: evaluation of the relationship between clinical relevance and rate of implementation in the SENATOR trial	18
Impact of COVID-19 on care-home mortality and life expectancy in Scotland	18
The My Active and Healthy Aging ICT platform prevents quality of life decline in older adults: a randomised controlled study	18
Understanding and identifying ways to improve hospital-based cancer care and treatment for people with dementia: an ethnographic study	18
The experience of uncertainty for patients, families and healthcare providers in post-stroke palliative and end-of-life care: a qualitative meta-synthesis	18
Individualisation of glycaemic management in older people with type 2 diabetes: a systematic review of clinical practice guidelines recommendations	18
Acceptance and commitment therapy for late-life treatment-resistant generalised anxiety disorder: a feasibility study	18
Barriers and potential solutions in the recruitment and retention of older patients in clinical trials—lessons learned from six large multicentre randomized controlled trials	17
‘What matters to you?’ Health outcome prioritisation in treatment decision-making for older patients	17
Patients’ preferred place of death: patients are willing to consider their preferences, but someone has to ask them	17
Atypical symptoms, SARS-CoV-2 test results and immunisation rates in 456 residents from eight nursing homes facing a COVID-19 outbreak	17
Preoperative comprehensive geriatric assessment and optimisation prior to elective arterial vascular surgery: a health economic analysis	17
Calculating the carbon footprint of a Geriatric Medicine clinic before and after COVID-19	17
Interventions to ameliorate reductions in muscle quantity and function in hospitalised older adults: a systematic review towards acute sarcopenia treatment	17
The Hospital Frailty Risk Score—outcomes in specialised services	17
Long-term effect of a 24-week multicomponent intervention on physical performance and frailty in community-dwelling older adults	17
Neuropsychiatric symptoms in early stage of Alzheimer’s and non-Alzheimer’s dementia, and the risk of progression to severe dementia	17
Positive scores on the 4AT delirium assessment tool at hospital admission are linked to mortality, length of stay and home time: two-centre study of 82,770 emergency admissions	17

New Horizons in the impact of frailty on pharmacokinetics: latest developments	17
Feasibility and acceptability of the ‘Acutely Presenting Older Patient’ screener in routine emergency department care	16
The disability process: is there a place for frailty?	16
Associations of handgrip strength with all-cause and cancer mortality in older adults: a prospective cohort study in 28 countries	16
Dementia and hearing-aid use: a two-way street	16
Impact of frailty on health-related quality of life 1 year after transcatheter aortic valve implantation	16
Long-term conditions, multimorbidity, lifestyle factors and change in grip strength over 9 years of follow-up: Findings from 44,315 UK biobank participants	16
Patient-related risk factors for in-hospital functional decline in older adults: A systematic review and meta-analysis	16
A practitioner behaviour change intervention for deprescribing in the hospital setting	16
Barriers and facilitators to nursing delirium screening in older emergency patients: a qualitative study using the theoretical domains framework	16
The association between the inflammatory response following surgery and post-operative delirium in older oncological patients: a prospective cohort study	16
Sarcopenia is associated with 3-month and 1-year mortality in geriatric rehabilitation inpatients: RESORT	16
Frailty trajectories in three longitudinal studies of aging: Is the level or the rate of change more predictive of mortality?	16
Pathways to help-seeking for sexual difficulties in older adults: qualitative findings from the third National Survey of Sexual Attitudes and Lifestyles (Natsal-3)	16
Current characteristics and early functional outcome of older stroke patients: a population-based study (Dijon Stroke Registry)	16
The COVID rehabilitation paradox: why we need to protect and develop geriatric rehabilitation services in the face of the pandemic	15
New horizons in life extension, healthspan extension and exceptional longevity	15
Physical frailty, adherence to ideal cardiovascular health and risk of cardiovascular disease: a prospective cohort study	15
The nurse-coordinated cardiac care bridge transitional care programme: a randomised clinical trial	15
Risk of progression to diabetes and mortality in older people with prediabetes: The English longitudinal study on ageing	15
Understanding consumer perceptions of frailty screening to inform knowledge translation and health service improvements	15
Hospital frailty risk score and adverse health outcomes: evidence from longitudinal record linkage cardiac data	15
Xerostomia and polypharmacy among dependent older New Zealanders: a national survey	15
Are presymptomatic SARS-CoV-2 infections in nursing home residents unrecognised symptomatic infections? Sequence and metadata from weekly testing in an extensive nursing home outbreak	15
The impact of pain on the course of ADL functioning in patients with dementia	15
From Warkworth House to the 21st century care homes: progress marked by persistent challenges	14
Mortality in hip fracture patients after implementation of a nurse practitioner-led orthogeriatric care program: results of a 1-year follow-up	14
Frailty—a risk factor of global and domain-specific cognitive decline among a nationally representative sample of community-dwelling older adult U.S. Medicare beneficiaries	14
New horizons in the perioperative care of older adults	14
Association of plasma FGF21 levels with muscle mass and muscle strength in a national multicentre cohort study: Korean Frailty and Aging Cohort Study	14
The role of sodium-glucose co-transporter-2 inhibitors in frail older adults with or without type 2 diabetes mellitus	14
Unmet healthcare needs among middle-aged and older adults in China	14
Effects of a 12-week Vivifrail exercise program on intrinsic capacity among frail cognitively impaired community-dwelling older adults: secondary analysis of a multicentre randomised clinical trial	14
Effectiveness of acute geriatric unit care on functional decline, clinical and process outcomes among hospitalised older adults with acute medical complaints: a systematic review and meta-analysis	14
Impact of modifiable healthy lifestyle adoption on lifetime gain from middle to older age	14
Effect of various exercises on frailty among older adults with subjective cognitive concerns: a randomised controlled trial	14
Inspiratory muscle training for improving inspiratory muscle strength and functional capacity in older adults: a systematic review and meta-analysis	14
Dynamic statistical model for predicting the risk of death among older Chinese people, using longitudinal repeated measures of the frailty index: a prospective cohort study	14
Moving more, ageing happy: findings from six low- and middle-income countries	13
Prevalence, management and outcomes of unrecognized delirium in a National Sample of 1,493 older emergency department patients: how many were sent home and what happened to them?	13
COVID-19 outbreak: organisation of a geriatric assessment and coordination unit. A French example	13
Effect of an integrated care model for pre-frail and frail older people living in community	13
Including older people in health and social care research: best practice recommendations based on the INCLUDE framework	13
Linkage of national health and social care data: a cross-sectional study of multimorbidity and social care use in people aged over 65 years in Scotland	13
Are we allowed to visit now? Concerns and issues surrounding vaccination and infection risks in UK care homes during COVID-19	13
The impact of an exercise intervention on frailty levels in hospitalised older adults: secondary analysis of a randomised controlled trial	13
Frailty transitions and prevalence in an ageing population: longitudinal analysis of primary care data from an open cohort of adults aged 50 and over in England, 2006–2017	13
Age and clinical outcomes after hip fracture surgery: do octogenarian, nonagenarian and centenarian classifications matter?	13
Development and evaluation of an evidence-based, theory-grounded online Clinical Frailty Scale tutorial	13
Assessment of coding-based frailty algorithms for long-term outcome prediction among older people in community settings: a cohort study from the Shizuoka Kokuho Database	13
Neurodegenerative disease is associated with increased incidence of epilepsy: a population based study of older adults	13
Implementing post-diagnostic support for people living with dementia in England: a qualitative study of barriers and strategies used to address these in practice	13
Exploring the reciprocal relationship between cognitive function and edentulism among middle-aged and older adults in China	13
‘The worse my hearing got, the less sociable I got’: a qualitative study of patient and professional views of the management of social isolation and hearing loss	12
How do people living with dementia perceive eating and drinking difficulties? A qualitative study	12
Decisions on antibiotic prescribing for suspected urinary tract infections in frail older adults: a qualitative study in four European countries	12
Time-efficient physical activity interventions to reduce blood pressure in older adults: a randomised controlled trial	12
Individual changes in anthropometric measures after age 60 years: a 15-year longitudinal population-based study	12
Barriers and enablers to deprescribing in long-term care facilities: a ‘best-fit’ framework synthesis of the qualitative evidence	12
Medical assistance in dying and older persons in Belgium: trends, emerging issues and challenges	12
Developing a virtual geriatric perioperative medicine clinic: a mixed methods healthcare improvement study	12
The need for improved discharge criteria for hospitalised patients with COVID-19—implications for patients in long-term care facilities	12
Anaemia and physical and mental health in the very old: An individual participant data meta-analysis of four longitudinal studies of ageing	12
Clinical clustering of eight orthostatic haemodynamic patterns in The Irish Longitudinal Study on Ageing (TILDA)	12
Effect of an ongoing pharmacist service to reduce medicine-induced deterioration and adverse reactions in aged-care facilities (nursing homes): a multicentre, randomised controlled trial (the ReMInDAR	12
The burden of psychotropic and anticholinergic medicines use in care homes: population-based analysis in 147 care homes	12
The relationship between frailty and delirium: insights from the 2017 Delirium Day study	12
A qualitative evaluation of the effect of a longitudinal dementia education programme on healthcare student knowledge and attitudes	12
A dose response relationship between accelerometer assessed daily steps and depressive symptoms in older adults: a two-year cohort study	12
The impact of study factors in the association of periodontal disease and cognitive disorders: systematic review and meta-analysis	12
Bi-directional associations of epilepsy with dementia and Alzheimer’s disease: a systematic review and meta-analysis of longitudinal studies	12
Longitudinal associations between falls and future risk of cognitive decline, the Motoric Cognitive Risk syndrome and dementia: the Einstein Ageing Study	12
Prevalence of initial orthostatic hypotension in older adults: a systematic review and meta-analysis	11
Is ambient air pollution associated with sarcopenia? Results from a nation-wide cross-sectional study	11
Healthcare for older people in lower and middle income countries	11
Use of a digital delirium pathway and quality improvement to improve delirium detection in the emergency department and outcomes in an acute hospital	11
Efficacy of exercise-based interventions in preventing falls among community-dwelling older persons with cognitive impairment: is there enough evidence? An updated systematic review and meta-analysis	11
Potentially inappropriate medication use in older adults with mild-moderate Alzheimer’s disease: prevalence and associations with adverse events	11
Acute sarcopenia changes following hospitalization: influence of pre-admission care dependency level	11
Using video consultation technology between care homes and health and social care professionals: a scoping review and interview study during COVID-19 pandemic	11
‘Unprepared for the depth of my feelings’ - Capturing grief in older people through research poetry	11
Effect of frailty on outcomes of endovascular treatment for acute ischaemic stroke in older patients	11
Gait and falls in cerebral small vessel disease: a systematic review and meta-analysis	11
Balance and cognitive decline in older adults in the cardiovascular health study	11
The frailty index based on laboratory test data as a tool to investigate the impact of frailty on health outcomes: a systematic review and meta-analysis	11
Motoric cognitive risk syndrome and incident dementia in older adults from the Québec NuAge cohort	11
Hospital nurses’ management of agitation in older cognitively impaired patients: do they recognise pain-related agitation?	11
Erectile dysfunction predicts mortality in middle-aged and older men independent of their sex steroid status	11
Calf circumference refines sarcopenia in correlating with mortality risk	11
Screening instruments for cognitive impairment in older patients in the Emergency Department: a systematic review and meta-analysis	11
Problems faced by people living at home with dementia and incontinence: causes, consequences and potential solutions	11
The association between loneliness and medication use in older adults	11
The role of resistance exercise training for improving cardiorespiratory fitness in healthy older adults: a systematic review and meta-analysis	11
Prevention and infection control of COVID-19 in nursing homes: experience from China	11
Faecal microbiota transplantation as a home therapy to frail older people	11