American Journal of Psychiatry

Article	Citations
Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression	316
The American Psychiatric Association Practice Guideline for the Treatment of Patients With Schizophrenia	303
Psychedelics and Psychedelic-Assisted Psychotherapy	288
Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation	271
Stanford Neuromodulation Therapy (SNT): A Double-Blind Randomized Controlled Trial	229
The Critical Relationship Between Anxiety and Depression	216
Improving Suicide Prevention Through Evidence-Based Strategies: A Systematic Review	204
Multimodal Abnormalities of Brain Structure and Function in Major Depressive Disorder: A Meta-Analysis of Neuroimaging Studies	192
Mental Health Response to the COVID-19 Outbreak in China	183
Distinct Symptom-Specific Treatment Targets for Circuit-Based Neuromodulation	179
Identification of Common Neural Circuit Disruptions in Emotional Processing Across Psychiatric Disorders	178
Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia	135
20-Year Trends in the Pharmacologic Treatment of Bipolar Disorder by Psychiatrists in Outpatient Care Settings	130
Reduction in Mental Health Treatment Utilization Among Transgender Individuals After Gender-Affirming Surgeries: A Total Population Study	127
A Randomized Controlled Trial of Repeated Ketamine Administration for Chronic Posttraumatic Stress Disorder	121
Hormonal Treatments for Major Depressive Disorder: State of the Art	121
An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression	120
From Womb to Neighborhood: A Racial Analysis of Social Determinants of Psychosis in the United States	120
Subcortical Brain Volume, Regional Cortical Thickness, and Cortical Surface Area Across Disorders: Findings From the ENIGMA ADHD, ASD, and OCD Working Groups	116
Neuroimaging Biomarkers in Schizophrenia	114
Elevated C-Reactive Protein in Patients With Depression, Independent of Genetic, Health, and Psychosocial Factors: Results From the UK Biobank	106
Variable Patterns of Remission From ADHD in the Multimodal Treatment Study of ADHD	105
A Population-Based Cohort Study Examining the Incidence and Impact of Psychotic Experiences From Childhood to Adulthood, and Prediction of Psychotic Disorder	95
Addiction as a Coping Response: Hyperkatifeia, Deaths of Despair, and COVID-19	93
A Brain-Centric Model of Suicidal Behavior	92

Harmonizing the Neurobiology and Treatment of Obsessive-Compulsive Disorder	88
The Overlapping Neurobiology of Induced and Pathological Anxiety: A Meta-Analysis of Functional Neural Activation	88
Dismantling Structural Racism in Psychiatry: A Path to Mental Health Equity	85
Association of Prenatal Alcohol Exposure With Psychological, Behavioral, and Neurodevelopmental Outcomes in Children From the Adolescent Brain Cognitive Development Study	84
The State of Our Understanding of the Pathophysiology and Optimal Treatment of Depression: Glass Half Full or Half Empty?	83
Anticholinergic Medication Burden–Associated Cognitive Impairment in Schizophrenia	80
Toward Circuit Mechanisms of Pathophysiology in Depression	76
Psychotherapy at a Distance	75
The Impact of COVID-19 on Individuals With Intellectual and Developmental Disabilities: Clinical and Scientific Priorities	75
Association Between Systemic Inflammation and Individual Symptoms of Depression: A Pooled Analysis of 15 Population-Based Cohort Studies	72
The Mental Health Effects of COVID-19 on Health Care Providers in China	70
Effects of Olanzapine Combined With Samidorphan on Weight Gain in Schizophrenia: A 24-Week Phase 3 Study	68
Autism Spectrum Disorder Genetics and the Search for Pathological Mechanisms	67
Genome-Wide Association Study of Suicide Death and Polygenic Prediction of Clinical Antecedents	62
A Genetics-First Approach to Dissecting the Heterogeneity of Autism: Phenotypic Comparison of Autism Risk Copy Number Variants	60
Identification of a Signaling Mechanism by Which the Microbiome Regulates Th17 Cell-Mediated Depressive-Like Behaviors in Mice	58
Efficacy of Intravenous Ketamine in Adolescent Treatment-Resistant Depression: A Randomized Midazolam-Controlled Trial	57
Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts	56
Distinct Polygenic Score Profiles in Schizophrenia Subgroups With Different Trajectories of Cognitive Development	56
Alcohol Use Disorder and Risk of Suicide in a Swedish Population-Based Cohort	55
Association Between Ambient Air Pollution and Daily Hospital Admissions for Depression in 75 Chinese Cities	54
Large-Scale Functional Brain Network Architecture Changes Associated With Trauma-Related Dissociation	54
Maintenance Treatment With Long-Acting Injectable Antipsychotics for People With Nonaffective Psychoses: A Network Meta-Analysis	54
Mapping Subcortical Brain Alterations in 22q11.2 Deletion Syndrome: Effects of Deletion Size and Convergence With Idiopathic Neuropsychiatric Illness	54
Examining the Reach of Smartphone Apps for Depression and Anxiety	54
Age Differences in the Neural Correlates of Anxiety Disorders: An fMRI Study of Response to Learned Threat	51
Sleep Onset Problems and Subcortical Development in Infants Later Diagnosed With Autism Spectrum Disorder	51
Disparities in Screening and Treatment of Cardiovascular Diseases in Patients With Mental Disorders Across the World: Systematic Review and Meta-Analysis of 47 Observational Studies	51
Well-Being, Burnout, and Depression Among North American Psychiatrists: The State of Our Profession	49
Defining Recovery From Alcohol Use Disorder: Development of an NIAAA Research Definition	49
Lead-Time Bias Confounds Association Between Duration of Untreated Psychosis and Illness Course in Schizophrenia	48
Efficacy and Safety of Lumateperone for Major Depressive Episodes Associated With Bipolar I or Bipolar II Disorder: A Phase 3 Randomized Placebo-Controlled Trial	48
Pervasively Thinner Neocortex as a Transdiagnostic Feature of General Psychopathology	48
Intergenerational Effects of Maternal Holocaust Exposure on FKBP5 Methylation	48
Early Adversity and Development: Parsing Heterogeneity and Identifying Pathways of Risk and Resilience	48
Effect Sizes of Deletions and Duplications on Autism Risk Across the Genome	47
The Relationship Between White Matter Microstructure and General Cognitive Ability in Patients With Schizophrenia and Healthy Participants in the ENIGMA Consortium	47
Alcohol, Tobacco, and Comorbid Psychiatric Disorders and Associations With Sexual Identity and Stress-Related Correlates	46
Functional Connectome Prediction of Anxiety Related to the COVID-19 Pandemic	46
Adjunctive Ketamine With Relapse Prevention–Based Psychological Therapy in the Treatment of Alcohol Use Disorder	45
Effect of AXS-05 (Dextromethorphan-Bupropion) in Major Depressive Disorder: A Randomized Double-Blind Controlled Trial	45
Subjective Responses to Alcohol in the Development and Maintenance of Alcohol Use Disorder	45
Associations of Benzodiazepines, Z-Drugs, and Other Anxiolytics With Subsequent Dementia in Patients With Affective Disorders: A Nationwide Cohort and Nested Case-Control Study	44
The Evolving Nexus of Sleep and Depression	44
Incident Major Depressive Disorder Predicted by Three Measures of Insulin Resistance: A Dutch Cohort Study	44
Sleep Abnormalities in Schizophrenia: State of the Art and Next Steps	43
Structural Racism and Suicide Prevention for Ethnoracially Minoritized Youth: A Conceptual Framework and Illustration Across Systems	42
Risks and Benefits of Cannabis and Cannabinoids in Psychiatry	41
REL-1017 (Esmethadone) as Adjunctive Treatment in Patients With Major Depressive Disorder: A Phase 2a Randomized Double-Blind Trial	41
Rapid Implementation of Telehealth in Hospital Psychiatry in Response to COVID-19	41

The Intergenerational Impact of Structural Racism and Cumulative Trauma on Depression	40
Association of Inflammatory Activity With Larger Neural Responses to Threat and Reward Among Children Living in Poverty	40
Antibodies From Children With PANDAS Bind Specifically to Striatal Cholinergic Interneurons and Alter Their Activity	40
Toward a Better Understanding of the Mechanisms and Pathophysiology of Anhedonia: Are We Ready for Translation?	40
Charting the Landscape of Genetic Overlap Between Mental Disorders and Related Traits Beyond Genetic Correlation	39
Disrupted Dorsal Mid-Insula Activation During Interoception Across Psychiatric Disorders	39
Early Parenting Intervention Effects on Brain Responses to Maternal Cues Among High-Risk Children	38
On the Genetic and Environmental Relationship Between Suicide Attempt and Death by Suicide	38
Polygenic Risk and Progression to Bipolar or Psychotic Disorders Among Individuals Diagnosed With Unipolar Depression in Early Life	38
Mental Health Service Use and Psychopharmacological Treatment Following Psychotic Experiences in Preadolescence	38
On the Origins of Schizophrenia	38
Brain Reward System Dysfunction in Adolescence: Current, Cumulative, and Developmental Periods of Depression	38
Maternal Psychological Resilience During Pregnancy and Newborn Telomere Length: A Prospective Study	38
Functional Neuroimaging in PTSD: From Discovery of Underlying Mechanisms to Addressing Diagnostic Heterogeneity	38
Ulipristal Acetate for Treatment of Premenstrual Dysphoric Disorder: A Proof-of-Concept Randomized Controlled Trial	37
Brain-Based Biotypes of Psychiatric Vulnerability in the Acute Aftermath of Trauma	37
Neural Insensitivity to the Effects of Hunger in Women Remitted From Anorexia Nervosa	37
Whole Brain White Matter Tract Deviation and Idiosyncrasy From Normative Development in Autism and ADHD and Unaffected Siblings Link With Dimensions of Psychopathology and Cognition	35
Association of Prefrontal-Striatal Functional Pathology With Alcohol Abstinence Days at Treatment Initiation and Heavy Drinking After Treatment Initiation	35
Contraception for Women With Psychiatric Disorders	35
Fifty Years of Research on Schizophrenia: The Ascendance of the Glutamatergic Synapse	34
Diagnostic Classification for Human Autism and Obsessive-Compulsive Disorder Based on Machine Learning From a Primate Genetic Model	34
New Challenges in Addiction Medicine: COVID-19 Infection in Patients With Alcohol and Substance Use Disorders—The Perfect Storm	34
Impact of the KCNQ2/3 Channel Opener Ezogabine on Reward Circuit Activity and Clinical Symptoms in Depression: Results From a Randomized Controlled Trial	33
Examining and Modulating Neural Circuits in Psychiatric Disorders With Transcranial Magnetic Stimulation and Electroencephalography: Present Practices and Future Developments	33
Long-Term Cannabis Use and Cognitive Reserves and Hippocampal Volume in Midlife	33
Anxiety, Depression, and Suicide in Youth	33
Electroconvulsive Therapy in Mania: A Review of 80 Years of Clinical Experience	33
The American Psychiatric Association Practice Guideline for the Treatment of Patients With Eating Disorders	32
Zuranolone for the Treatment of Postpartum Depression	32
Telehealth During COVID-19—Does Everyone Have Equal Access?	32
Clozapine Intoxication in COVID-19	32
Thalamic Nuclei Volumes in Psychotic Disorders and in Youths With Psychosis Spectrum Symptoms	31
Differential Patterns of Delayed Emotion Circuit Maturation in Abused Girls With and Without Internalizing Psychopathology	31
Cell-Type-Specific Impact of Glucocorticoid Receptor Activation on the Developing Brain: A Cerebral Organoid Study	31
Coordinate-Based Network Mapping of Brain Structure in Major Depressive Disorder in Younger and Older Adults: A Systematic Review and Meta-Analysis	31
The Sources of Parent-Child Transmission of Risk for Suicide Attempt and Deaths by Suicide in Swedish National Samples	31
Genes To Mental Health (G2MH): A Framework to Map the Combined Effects of Rare and Common Variants on Dimensions of Cognition and Psychopathology	31
A Novel, Brief, Fully Automated Intervention to Extend the Antidepressant Effect of a Single Ketamine Infusion: A Randomized Clinical Trial	31
Moderation of Prazosin’s Efficacy by Alcohol Withdrawal Symptoms	31
Childhood Maltreatment and Mental Health Problems: A Systematic Review and Meta-Analysis of Quasi-Experimental Studies	31
Diagnosis- and Cell Type-Specific Mitochondrial Functional Pathway Signatures in Schizophrenia and Bipolar Disorder	30
Augmenting Computerized Cognitive Training With Vortioxetine for Age-Related Cognitive Decline: A Randomized Controlled Trial	30
Surging Racial Disparities in the U.S. Overdose Crisis	30
Evaluating the Machine Learning Literature: A Primer and User’s Guide for Psychiatrists	29
20-Year Prospective, Sequential Follow-Up Study of Heterogeneity in Associations of Duration of Untreated Psychosis With Symptoms, Functioning, and Quality of Life Following First-Episode Psychosis	29
Association Between the Use of Cannabis and Physical Violence in Youths: A Meta-Analytical Investigation	29
Association of ECT With Risks of All-Cause Mortality and Suicide in Older Medicare Patients	29
Muscarinic Acetylcholine Receptor Agonists as Novel Treatments for Schizophrenia	29
Subcortical Brain Development in Autism and Fragile X Syndrome: Evidence for Dynamic, Age- and Disorder-Specific Trajectories in Infancy	28
Trends in Outpatient Psychotherapy Provision by U.S. Psychiatrists: 1996–2016	28
Persistent Dissociation and Its Neural Correlates in Predicting Outcomes After Trauma Exposure	28
U.S. Adults With Pain, a Group Increasingly Vulnerable to Nonmedical Cannabis Use and Cannabis Use Disorder: 2001–2002 and 2012–2013	28
Interindividual Differences in Cortical Thickness and Their Genomic Underpinnings in Autism Spectrum Disorder	27
Racial Disparities in Adversity During Childhood and the False Appearance of Race-Related Differences in Brain Structure	27
Nicotine Use and DSM-IV Nicotine Dependence in the United States, 2001–2002 and 2012–2013	27
Functional Connectivity Mapping for rTMS Target Selection in Depression	27
Association of Missense Mutation in FOLH1 With Decreased NAAG Levels and Impaired Working Memory Circuitry and Cognition	27
Two Decades of Anxiety Neuroimaging Research: New Insights and a Look to the Future	26
Psychiatry Diversity Leadership in Academic Medicine: Guidelines for Success	26
CBT for Prolonged Grief in Children and Adolescents: A Randomized Clinical Trial	26
From Rare Copy Number Variants to Biological Processes in ADHD	26
Evidence for Dopamine Abnormalities in the Substantia Nigra in Cocaine Addiction Revealed by Neuromelanin-Sensitive MRI	25
Must Psilocybin Always “Assist Psychotherapy”?	25
In Search of Biomarkers to Guide Interventions in Autism Spectrum Disorder: A Systematic Review	24
A Prehistory of the Diathesis-Stress Model: Predisposing and Exciting Causes of Insanity in the 19th Century	24
Evolution, Emotion, and Episodic Engagement	24
The Autism Biomarkers Consortium for Clinical Trials: Initial Evaluation of a Battery of Candidate EEG Biomarkers	24
Treatment-Specific Associations Between Brain Activation and Symptom Reduction in OCD Following CBT: A Randomized fMRI Trial	24
Reward Processing in Children With Disruptive Behavior Disorders and Callous-Unemotional Traits in the ABCD Study	24
Flexible Buprenorphine/Naloxone Model of Care for Reducing Opioid Use in Individuals With Prescription-Type Opioid Use Disorder: An Open-Label, Pragmatic, Noninferiority Randomized Controlled Trial	24
Impact of COVID-19 Telehealth Policy Changes on Buprenorphine Treatment for Opioid Use Disorder	24
Multimodal Neuroimaging of Suicidal Thoughts and Behaviors in a U.S. Population-Based Sample of School-Age Children	23
Let’s Be Clear That “Autism Spectrum Disorder Symptoms” Are Not Always Related to Autism Spectrum Disorder	23
Time Course of Relapse Following Acute Treatment for Anorexia Nervosa	23
Variable Emergence of Autism Spectrum Disorder Symptoms From Childhood to Early Adulthood	23
Effect of Experimental Manipulation of the Orbitofrontal Cortex on Short-Term Markers of Compulsive Behavior: A Theta Burst Stimulation Study	23
Zuranolone for the Treatment of Adults With Major Depressive Disorder: A Randomized, Placebo‐Controlled Phase 3 Trial	23
The Importance of Conduct Disorder in the Treatment of Violence in Schizophrenia: Efficacy of Clozapine Compared With Olanzapine and Haloperidol	23
Contribution of Intellectual Disability–Related Genes to ADHD Risk and to Locomotor Activity in Drosophila	22

Prevalence and Correlates of Cannabis Use and Cannabis Use Disorder Among U.S. Veterans: Results From the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC-III)	22
Association Between Benzodiazepine or Z-Drug Prescriptions and Drug-Related Poisonings Among Patients Receiving Buprenorphine Maintenance: A Case-Crossover Analysis	22
The Rearing Environment and Risk for Major Depression: A Swedish National High-Risk Home-Reared and Adopted-Away Co-Sibling Control Study	22
Sustained Effect of a Brief Video in Reducing Public Stigma Toward Individuals With Psychosis: A Randomized Controlled Trial of Young Adults	22
The Amygdala and Depression: A Sober Reconsideration	21
Decoding Shared Versus Divergent Transcriptomic Signatures Across Cortico-Amygdala Circuitry in PTSD and Depressive Disorders	21
Trends in Cannabis Use Disorder Diagnoses in the U.S. Veterans Health Administration, 2005–2019	21
Association of Neural Reward Circuitry Function With Response to Psychotherapy in Youths With Anxiety Disorders	21
The Prehistory of Psychiatric Genetics: 1780–1910	21
The Neglected Role of Psychotherapy for Treatment-Resistant Depression	20
Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial	20
Intrusive Traumatic Reexperiencing: Pathognomonic of the Psychological Response to Traumatic Stress	20
Association of Cannabis Use–Related Predictor Variables and Self-Reported Psychotic Disorders: U.S. Adults, 2001–2002 and 2012–2013	20
Structural Racism as a Proximal Cause for Race-Related Differences in Psychiatric Disorders	19
Predictive Value of Acute Neuroplastic Response to rTMS in Treatment Outcome in Depression: A Concurrent TMS-fMRI Trial	19
Synaptic Variability and Cortical Gamma Oscillation Power in Schizophrenia	19
The World Health Organization Risk Drinking Levels Measure of Alcohol Consumption: Prevalence and Health Correlates in Nationally Representative Surveys of U.S. Adults, 2001–2002 and 2012–2013	19
Sublingual Buprenorphine-Naloxone Compared With Injection Naltrexone for Opioid Use Disorder: Potential Utility of Patient Characteristics in Guiding Choice of Treatment	18
Do Benzodiazepines Cause Alzheimer’s Disease?	18
Mood Disorders and Outcomes of COVID-19 Hospitalizations	18
What Does It Mean to Be Transdiagnostic and How Would We Know?	18
Learning About Safety: Conditioned Inhibition as a Novel Approach to Fear Reduction Targeting the Developing Brain	18
Disruptive Behavior Disorders: The Challenge of Delineating Mechanisms in the Face of Heterogeneity	18
Transforming Discoveries About Cortical Microcircuits and Gamma Oscillations Into New Treatments for Cognitive Deficits in Schizophrenia	17
A Call to Protect the Health Care Workers Fighting COVID-19 in the United States	17
From Awareness to Action: An Urgent Call to Address the Inadequacy of Treatment for Anorexia Nervosa	17
Association of Medication Treatment for Opioid Use Disorder With Suicide Mortality	17
Genetics and Brain Transcriptomics of Completed Suicide	17
Intentional Drug Overdose Deaths in the United States	17
GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors	17
Schizophrenia Imaging Signatures and Their Associations With Cognition, Psychopathology, and Genetics in the General Population	17