Analyst

Article	Citations
Sulfur atom modification on thymine improves the specificity and sensitivity of DNA polymerization and detection	109
Measurement of enzyme activity of insoluble substrates based on ordered porous layer interferometry and the application in evaluation of thrombolytic drugs	81
Conductive phthalocyanine-based porous organic polymer as sensing platform for rapid determination of vanillin	81
Recent development of nanotechnology-empowered antigen assay methods for the control of infectious diseases	76
Fluoroponytailed ionic liquids as co-porogens for poly(butyl methacrylate-co-ethylene dimethacrylate) monolithic supports for thin layer chromatography	73
Single-particle spectroelectrochemistry: electrochemical tuning of plasmonic properties via mercury amalgamation in mesoporous silica coated gold nanorods without structural deformation	69
An electrochemiluminescence immunosensor based on multipath signal catalytic amplification integrated in a Cu2+–PEI–Pt/AuNC nanocomposite	69
An enzyme cascade fluorescence-based assay for the quantification of phenylalanine in serum	68
Profiling humoral responses to COVID-19 immunization in Kawasaki disease using SARS-CoV-2 variant protein microarrays	66
Identification of the first selective bioluminescent probe for real-time monitoring of carboxylesterase 2 in vitro and in vivo	54
High-precision Helicobacter pylori infection diagnosis using a dual-element multimodal gas sensor array	52
Front cover	52
MIP integrated surface plasmon resonance in vitro detection of sodium benzoate	48
Self-assembled DNA dendrons as signal amplifiers in a DNA probe-based chemiluminescence assay for enhanced colorimetric detection of short target cDNA	46
Simultaneous two-color visualization of lipid droplets and lysosomes for cell homeostasis monitoring using a single fluorescent probe	46
Real-time measurement of the trans-epithelial electrical resistance in an organ-on-a-chip during cell proliferation	45
Amplifying the electrochemical footprint of <1000 molecules in a dissolving microdroplet	44
Design and optimization of an octuple-electrode array for micro-particle chain rotation via electrorotation integrated with machine vision technology	44
Highly sensitive CD40L protein discrimination via label-free fiber sensing technologies	43
Surface-enhanced Raman spectroscopy with single cell manipulation by microfluidic dielectrophoresis	41
Front cover	40
Contents list	38
Sensitive detection of genetically modified maize based on a CRISPR/Cas12a system	38
Front cover	38
A sample-to-answer DNA detection microfluidic system integrating sample pretreatment and smartphone-readable gradient plasmonic photothermal continuous-flow PCR	37

Back cover	37
Contents list	35
Back cover	35
Contents list	34
A strategy to link the changes in the quality traits of Japanese sea bass (Lateolabrax japonicus) muscle and proteins in its exudate during cold storage using mass spectrometry	34
Back cover	33
Fe-Doped polydopamine nanoparticles with peroxidase-mimicking activity for the detection of hypoxanthine related to meat freshness	33
Development of a near-infrared Raman spectroscopy setup compatible with fluorescence-guided surgery	32
Utilising highly conductive TPU “sticks” for facile and low-cost electroanalysis	31
Mass spectrometry-based techniques for single-cell analysis	30
Wireless rotating bipolar electrochemiluminescence for enzymatic detection	30
Stratification of tumour cell radiation response and metabolic signatures visualization with Raman spectroscopy and explainable convolutional neural network	30
Electroanalysis of meat discoloration: beef sarcoplasm extract with storage time	30
An electrochemical sensor based on AuPd@FexOy nanozymes for a sensitive and in situ quantitative detection of hydrogen peroxide in real samples	29
Multiplexing potential of NIR resonant and non-resonant Raman reporters for bio-imaging applications	29
Inside front cover	29
Water detection in organic solvents using a copolymer membrane immobilised with a fluorescent intramolecular charge transfer-type dye: effects of intramolecular hydrogen bonds	29
Nitrite anodic oxidation at Ni(ii)/Ni(iii)-decorated mesoporous SnO2 and its analytical applications	28
Highly catalytic and stable Au@AuPt nanoparticles for visual and quantitative detection of E. coli O157:H7	28
Contents list	27
Target-driven assembly of DNAzyme probes for simultaneous electrochemical detection of multiplex microRNAs	27
A smartphone-based portable device for Ag+ sensing using eco-synthesized carbon dots from mandarin peels	27
An enhanced fluorescent sensor system based on molecularly imprinted polymer chips with silver nanoparticles for highly-sensitive zearalenone analysis	26
Ti-based MOF nanosheets as a mass spectrometry imaging matrix for low molecular weight compounds to reveal the spatiotemporal content changes of hepatotoxic components during the processing of Poly	26
Influence of bovine and human serum albumin on the binding kinetics of biomolecular interactions	25
Recent progress in electrochemiluminescence microscopy analysis of single cells	25
Determination of cesium using nickel hexacyanoferrate by stripping voltammetry	25
Ultrafast protein digestion using an immobilized enzyme reactor following high-resolution mass spectrometry analysis for rapid identification of abrin toxin	25
A near-infrared fluorescent probe selectively recognizing cysteine to release H2S and its applications	24
Back cover	24
Nitrogen-doped orange emitting carbon dots for β-carotene detection and lysosomal imaging	24
Preparation of novel chiral stationary phases based on a chiral trianglsalen macrocycle by thiol-ene click chemistry for enantioseparation in high-performance liquid chromatography	24
Frequency-tuned selectivity enhancement of Mg@ZnO–TiO2 nanoflake-based heterojunction sensor devices	24
3D C–Co–N-anchored MWCNTs derived from metal–organic frameworks as high-performance electrochemical sensing platforms for the sensitive detection of adrenaline	24
Probe oscillation control in tapping-mode scanning probe electrospray ionization for stabilization of mass spectrometry imaging	24
Nondestructive assessment of tissue engineered cartilage based on biochemical markers in cell culture media: application of attenuated total reflection Fourier transform infrared (ATR-FTIR) spectrosco	23
Gold nanocluster-based ratiometric fluorescent probe for biosensing of Hg2+ ions in living organisms	23
Phenoxy-1,2-dioxetane-based activatable chemiluminescent probes: tuning of photophysical properties for tracing enzymatic activities in living cells	23
Ion-selective membrane modified microfluidic paper-based solution sampling substrates for potentiometric heavy metal detection	23
Lateral flow assay of pathogenic viruses and bacteria in healthcare	23
Urine protein quantification in human urine on boron-doped diamond electrodes based on the electrochemical reaction of Coomassie brilliant blue	22
Multiplex SERS detection of polycyclic aromatic hydrocarbon (PAH) pollutants in water samples using gold nanostars and machine learning analysis	22
A mitochondrion-targeted fluorescent probe based on ESIPT phthalimide for the detection of Hg2+ with large Stokes shift	22
Fluorescent and electrochemical detection of nuclease activity associated with Streptococcus pneumoniae using specific oligonucleotide probes	22
Noble metal-free SERS: mechanisms and applications	21
Contents list	21
Contents list	21
Back cover	21
Diazo-reaction based dual-mode colorimetric-electrochemical sensing of nitrite in pickled food	21
Back cover	21

Front cover	21
A paper-based ratiometric fluorescence sensor based on carbon dots modified with Eu3+ for the selective detection of tetracycline in seafood aquaculture water	21
Front cover	21
Back cover	21
Back cover	20
Curcumin – a natural colorant-based pH indicator for molecular diagnostics	20
The laccase mediator system at carbon nanotubes for anthracene oxidation and femtomolar electrochemical biosensing	20
Exploring the potential of Fourier transform-infrared spectroscopy of urine for non-invasive monitoring of inflammation associated with a kidney transplant	20
Thermal desorption bridged the gap between dielectric barrier discharge ionization and dried plasma spot samples for sensitive and rapid detection of fentanyl analogs in mass spectrometry	20
Augmentation of FTIR spectral datasets using Wasserstein generative adversarial networks for cancer liquid biopsies	20
A non-enzymatic highly stable electrochemical sensing platform based on allylamine capped copper nanoparticles for the detection of the soil nitrate content	20
Single-virus-sensitive barcode qPCR mediated by the aggregation of gold nanoparticle probes	19
Background free in vivo29Si MR imaging with hyperpolarized PEGylated silicon nanoparticles	19
Benchmarking TERS and TEPL probes: towards a reference sample for quantification of near-field enhancement factors in gap and non-gap modes	19
Fusion data from FT-IR and MALDI-TOF MS result in more accurate classification of specific microbiota	19
Quantitative fat analysis of milk using a line-illumination spatially offset Raman probe through carton packaging	19
Enzyme-triggered click chemistry combined with surface-enhanced Raman spectroscopy for the simple and sensitive detection of alkaline phosphatase activity from complex biological samples	19
Ultra-thin silica shell-guarded nanoflares for high-fidelity live cell miRNA-21 imaging by fully avoiding the interference of biothiols	19
A simple electrochemical strategy for the detection of the cancer marker CA19-9 by signal amplification using copper organic framework nanocomposite	19
Untargeted urine metabolite profiling by mass spectrometry aided by multivariate statistical analysis to predict prostate cancer treatment outcome	19
Microplasma-assisted synthesis of a mixed-valence Ce-MOF with enhanced oxidase-like activity for colorimetric sensing of dopamine	19
Simultaneous electrochemical detection of ozone and free chlorine with a boron-doped diamond electrode	19
A chemiluminescent sensor for imaging endogenous hydrogen polysulfides in a living system	19
Enzymatic glycoengineering-based spin labelling of cell surface sialoglycans to enable their analysis by electron paramagnetic resonance (EPR) spectroscopy	19
A deep clustering-based mass spectral data visualization strategy for anti-renal fibrotic lead compound identification from natural products	18
Back cover	18
Copper nanocluster-Ru(dcbpy)32+ as a cathodic ECL-RET probe combined with 3D bipedal DNA walker amplification for bioanalysis	18
Understanding electrocatalytic mechanisms and ultra-trace uranyl detection with Pd nanoparticles electrodeposited in deep eutectic solvents	18
Reflective epoxy resin/chitosan/PAA composite-functionalized fiber-optic interferometric probe sensor for sensitive heavy metal ion detection	18
Simultaneous analysis of acylcarnitines using MALDI-TOF mass spectrometry based on a parylene matrix chip	18
Correction: Voltammetric pH sensor based on electrochemically modified pseudo-graphite	18
Characterizing and understanding the photovoltage in n-Si/Au light-addressable electrochemical sensors	18
Visual electrochemiluminescence from an all-solid-state electrochemical cell	18
Discrimination of Robusta Amazônico coffee farmed by indigenous and non-indigenous people in Amazon: comparing benchtop and portable NIR using ComDim and duplex	18
An impedimetric approach for COVID-19 detection	18
Photonic–plasmonic resonator for SERS biodetection	18
Pseudopeptidic host adaptation in peptide recognition unveiled by ion mobility mass spectrometry	18
Determination of 3-monoiodotyrosine and 3,5-diiodotyrosine in newborn urine and dried urine spots by isotope dilution tandem mass spectrometry	18
Ratiometric fluorescent semiconducting polymer dots for temperature sensing	18
Local electrochemical sample acidification for the detection of Pb2+ traces	18
Serum-based ATR-FTIR spectroscopy combined with multivariate analysis for the diagnosis of pre-diabetes and diabetes	17
Cyanine dye-assembled composite upconversion nanoparticles for the sensing and cell imaging of nitrite based on a single particle imaging method	17
Liposome–exosome hybrids for in situ detection of exosomal miR-1246 in breast cancer	17
Differentiation of lactose sample batches from surface impurities by OrbiSIMS	17
Preparation of AuPt@ZIF-67 nanomaterials and their application in a flow injection chemiluminescence immunoassay	17
Extracellular vesicles derived from ovarian cancer cell lines discriminated by biochemical and Fourier transform infrared spectroscopy approaches	17
Ultrasensitive ratiometric fluorescent probes for Hg(ii) and trypsin activity based on carbon dots and metalloporphyrin via a target recycling amplification strategy	17
Insights into the cellular lipid cascade of prostate cells explored using infrared microspectroscopy	17
Squaraine probes for the bimodal staining of lipid droplets and endoplasmic reticulum imaging in live cells	17
A low-cost compact blood enzyme analyzer based on optical sensing for point-of-care liver function testing	17
A SERS and fluorescence dual-channel microfluidic droplet platform for exploring telomerase activity at the single-cell level	17
MAGPIX and FLEXMAP 3D Luminex platforms for direct detection of miR-122-5p through dynamic chemical labelling	17
Sensitive detection of synthetic cannabinoids in human blood using magnetic polydopamine molecularly imprinted polymer nanocomposites	17
A series of ultrasensitive electrocatalysts Fe-MOF/MWCNTs for fentanyl determination	17
FTIR characterisation of chondroitin sulfate E (CS-E) di-, tetra-, and hexasaccharide derivatives and their biotinylated or reducing conjugates	17
New insights into lipid and fatty acid metabolism from Raman spectroscopy	16
A minireview of recent developments in ozone detection using optical chemodosimeters	16
Dual-responsive Zr(iv) MOF based fluorometric sensor for rapid and selective detection of anti-cancer drug dacarbazine and herbicide oryzalin in environmental and biological samples	16
Back cover	16
Porous carbon-based robust, durable, and flexible electrochemical device for K+ detection in sweat	16
Selective non-enzymatic uric acid sensing in the presence of dopamine: electropolymerized poly-pyrrole modified with a reduced graphene oxide/PEDOT:PSS composite	16
An ion-selective chemiresistive platform as demonstrated for the detection of nitrogen species in water	16
Design of a photoelectrochemical lab-on-a-chip immunosensor based on enzymatic production of quantum dots in situ	16
Correction: High-efficiency and high-fidelity ssDNA circularisation via the pairing of five 3′-terminal bases to assist LR-LAMP for the genotyping of single-nucleotide polymorphisms	16
Contents list	16
Refined high-pressure tube design for improved resolution in high-pressure NMR spectroscopy	16
Understanding radiation response and cell cycle variation in brain tumour cells using Raman spectroscopy	16
SERS detection of thiram using a 3D sea cucumber-like composite flexible porous substrate	16
Visualizing nitroreductase activity in living cells and tissues under hypoxia and hepatic inflammation	16
Aptamer-functionalized two-photon SiO2@GQDs hybrid-based signal amplification strategy for targeted cancer imaging	16
Zinc pyrovanadate nanorods with excellent peroxidase-like activity at physiological pH for the colorimetric assay of H2O2 and epinephrine	16
“Lighting up” fluoride: cellular imaging and zebrafish model interrogations using a simple ESIPT-based mycophenolic acid precursor-based probe	16
Low background electrochemical sensor based on HCR towards acute myocardial infarction-specific miRNA detection	16
Enhancing fouling resistance of graphite sheets for electrochemical sensing of bisphenol-A	16
Rhodamine 6G-based efficient chemosensor for trivalent metal ions (Al3+, Cr3+ and Fe3+) upon single excitation with applications in combinational logic circuits and me	16
Selective detection of diethanolamine utilizing an LMR/LSPR-based optical fiber sensor	16
An ultrasensitive electrochemiluminescence biosensor for the detection of total bacterial count in environmental and biological samples based on a novel sulfur quantum dot luminophore	16
Exploring the potential of 3D-printed solvent activated electrodes for salicylic acid analysis	16
Serum IgG galactosylation as a potential biomarker for the diagnosis of echinococcosis	16
One-pot synthesized three-way junction based multiple strand displacement amplification for sensitive assay of H5N1 DNA	16

Spatially resolved quantification of oxygen consumption rate in ex vivo lymph node slices	16
FARPA-based tube array coupled with quick DNA extraction enables ultra-fast bedside detection of antibiotic-resistant pathogens	16
Monitoring bacterial spore metabolic activity using heavy water-induced Raman peak evolution	16
A cascade Fermat spiral microfluidic mixer chip for accurate detection and logic discrimination of cancer cells	16
An orthogonal barcoding enabled smart nanodevice for highly efficient isolation and proteomic profiling of tumor-derived extracellular vesicles	16
An efficient strategy with a synergistic effect of hydrophilic and electrostatic interactions for simultaneous enrichment of N- and O-glycopeptides	16
“Repair and fold” DNA nanotweezers for measuring DNA alkylation repair mediated by ALKBH	15
Portable particle mass spectrometer	15
I-motif sensor for the fluorometric detection of Monkeypox	15
Contents list	15
A facile visualized solid-phase detection of virus-specific nucleic acid sequences through an upconversion activated linear luminescence recovery process	15
Specific detection of fusion transcripts based on a duplex-specific nuclease and isothermal exponential amplification reaction	15
Contents list	15
Chemical conjugation to differentiate monosaccharides by Raman and surface enhanced Raman spectroscopy	15
A nano-biosensing platform based on CuS-BSA for label-free fluorescence detection of Escherichia coli	15
Back cover	15
Biomimetic -mineralized multifunctional nanoflowers for anodic-stripping voltammetric immunoassay of rehabilitation-related proteins	15
The facile activation of graphite for the improved determination of dopamine, rutin and acetamidophenol	15
Employing bulk-heterostructure conductive polymer PFO/PFBT for the photoelectrochemical analysis of p-phenylenediamine	15
Inside front cover	15
Online integration of capillary electrophoresis and dual detector Taylor dispersion analysis via a 3D printed instrument	15
A plasmon resonance-inspired discriminator unscrambles lipoprotein subtypes	15
Front cover	15
A parylene-mediated plasmonic–photonic hybrid fiber-optic sensor and its instrumentation for miniaturized and self-referenced biosensing	15
Tuning the electro-catalytic activity of the Zn–Cu MOF/rGO nanocomposite as a novel enzyme-free electrochemical sensor for the detection of the oxytocin hormone	14
Highly enantioselective recognition of S-ibuprofen by a host–guest induced chiral nanochannel	14
Rapid sub-nanomolar protein determination in serum using electropolymerized molecularly imprinted polymers (E-MIPs)	14
Estimation of biological variance in coherent Raman microscopy data of two cell lines using chemometrics	14
A proximity cleavage assisted DNAzyme catalyzed loading DNA walker system for accurate and sensitive small extracellular vesicle analysis	14
Inside front cover	14
Inside front cover	14
Recent progress in the development of porous carbon-based electrodes for sensing applications	14
Label-free SERS detection of foodborne pathogens based on a flexible PMMA-BP@MoS2 binary substrate	14
An intelligent readable and capture-antibody-independent lateral flow immunoassay based on Cu2−xSe nanocrystals for point-of-care detection of Escherichia coli O157:H7	14
Autodisplay of streptococcal protein G for construction of an orientation-controlled immunoaffinity layer	14
Portable and simultaneous detection of four respiratory pathogens through a microfluidic LAMP and real-time fluorescence assay	14
A dual-response NIR fluorescent probe for separately and continuously recognizing H2S and Cys with different fluorescence signals and its applications	14
Self-powered photoelectrochemical immunoassay of lactate dehydrogenase in melanoma patients based on the superposition of the interface polarization effect	14
Front cover	14
Front cover	14
Correction: In situ synthesis of chiral AuNCs with aggregation-induced emission using glutathione and ceria precursor nanosheets for glutathione biosensing	14
Borosilicate glass nanopipettes enhanced by synergistic electrostatic interactions and steric hindrance for ultrasensitive electrochemical detection of nanoplastics in environmental water samples	14
Acoustic detection of a mutation-specific Ligase Chain Reaction based on liposome amplification	14
A novel ratiometric fluorescent and colorimetric sensor based on a 1,8-naphthalimide derivative for nanomolar Cu2+ sensing: smartphone and food applications	14
A broadband picometer resolution visible CCD spectrometer based on virtually imaged phased array technology	14
Advancing triage of acute lymphoblastic leukaemia subtypes diagnosis: label-free Raman spectroscopy for precise single-cell phenotyping and subtype classification	14
A near-infrared optical nanosensor for measuring aerobic respiration in microbial systems	14
Themed collection: Biomedical Raman Imaging	14
Back cover	14
Back cover	14
Correction: An optical sensor for the sensitive determination of formaldehyde gas based on chromotropic acid and 4-aminoazobenzene immobilized in a hydrophilic membrane	14
Front cover	14
CRISPR/Cas13a-based single-nucleotide polymorphism detection for reliable determination of ABO blood group genotypes	14
Etched stainless steel wire modified with conjugated microporous polymers-F6 for jacket-free stir bar sorptive extraction of benzoylureas in juice sample	14
Correction: Machine learning encodes urine and serum metabolic patterns for autoimmune disease discrimination, classification and metabolic dysregulation analysis	13
Paper-based microfluidic device for serum zinc assay by colorimetry	13
Fluorescence imaging of intracellular telomerase activity for tumor cell identification by oligonucleotide-functionalized gold nanoparticles	13
Multivalent SnO2 quantum dot-decorated Ti3C2 MXene for highly sensitive electrochemical detection of Sudan I in food	13
A robust colorimetric aptasensor for the label-free detection of marine toxins based on tyrosine-capped gold nanoparticles	13
Rational design of NiO/Ti3C2Tx nanocomposites with enhanced triethylamine sensing performance	13
An ultra-sensitive ammonia sensor based on a quartz crystal microbalance using nanofibers overlaid with carboxylic group-functionalized MWCNTs	13
A microfluidic approach to study variations in Chlamydomonas reinhardtii alkaline phosphatase activity in response to phosphate availability	13
A novel AIE-active camphor-based fluorescent probe for simultaneous detection of Al3+ and Zn2+ at dual channels in living cells and zebrafish	13
Efficiency of direct photoinduced generation of singlet oxygen at different wavelengths, power density and exposure time of laser irradiation	13
Ratiometric fluorescent aptasensor for convenient detection of ochratoxin A in beer and orange juice	13
Nanoscale bond-selective imaging by computational fusion of atomic force microscopy and coherent anti-Stokes Raman scattering microscopy	13
Expression of concern: Comparison of photo- and Cu(i)-catalyzed “click” chemistries for the formation of carbohydrate SPR interfaces	13
Front cover	13
A highly sensitive caffeic acid fluorescent probe for detecting laccase in grape juice and mushrooms	13
Celebrating 100 years of chemistry at Nanjing University	13
Lubricin (PRG-4) anti-fouling coating for surface-enhanced Raman spectroscopy biosensing: towards a hierarchical separation system for analysis of biofluids	13
Standard addition method for rapid, cultivation-independent quantification of Legionella pneumophila cells by qPCR in biotrickling filters	13
Molecularly imprinted polymer sensors for biomarker detection in cardiovascular diseases	13
Multicomponent Raman spectral regression using complete and incomplete models and convolutional neural networks	13
High sensitivity and rapid detection of hepatitis B virus DNA using lateral flow biosensors based on Au@Pt nanorods in the absence of hydrogen peroxide	13
Ion parking in native mass spectrometry	13
Rapid and specific detection of intact viral particles using functionalized microslit silicon membranes as a fouling-based sensor	13
Visual detection of Cronobacter sakazakii on a microfluidic chip fabricated by a 3D molding method	13
Contents list	13
Contents list	13
Witnessing a discrete microdroplet freezing event via real-time electrochemical monitoring of solution temperature	13
Optical photothermal infrared spectroscopy and discrete wavenumber imaging for high content screening of single cells	13
Electrochemical detection of paracetamol based on CoO/Co3O4/NC nanocomposites derived from COFs	13
Reduction of background-triggered amplification in lesion-induced DNA amplification (LIDA)	13
A DNA tetrahedron-inspired magnetic hybrid with regular distribution of trypsin for ultra-fast digestion of proteins and glycoproteomics analysis	13
Integrated electrochemical lateral flow immunoassays (eLFIAs): recent advances	13
Continuous size-based DEP separation of particles using a bi-gap electrode pair	13
Analysis of blue and green REACH compliant tattoo inks	13
Nanobead handling on a centrifugal microfluidic LabDisk for automated extraction of cell-free circulating DNA with high recovery rates	12
Use of Raman spectroscopy for the label-free discrimination of CHO cells associated with antibody expression	12
Ratiometric fluorescent probes for pH mapping in cellular organelles	12
An affordable, handheld multimodal microscopic system with onboard cell morphology and counting features on a mobile device	12
Raman spectral classification algorithm of cephalosporin based on VGGNeXt	12
An extracellular electron transfer enhanced electrochemiluminescence aptasensor for Escherichia coli analysis	12
Single-particle study: effects of mercury amalgamation on morphological and spectral changes in anisotropic gold nanorods	12