OOIR: Observatory of International Research

Papers

(The H4-Index of Analytical Chemistry is 82. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Dual-Mode Label with Dynamic Cracking–Wrinkling Pattern and Ultralong-Lifetime Phosphorescence for Multilevel Anti-counterfeiting and Time-Resolved Message Encryption Applications	331
Detection and Analysis of Reactive Oxygen Species (ROS): Buffer Components Are Not Bystanders	311
A Monolith-Based μHPLC-SERS Integrated Microplatform Featuring Mg²⁺-Regulated Dual-Capture Mechanism for Real-Time Online ATP Monitoring	234
C₂H₄ as a Novel Reaction Gas for Eliminating ²³⁸U Isobaric Interference in Ultratrace Plutonium Isotope (²³⁸Pu, ²³⁹Pu, ²⁴⁰Pu, and	223
Reconstructing Super-Resolution Raman Spectral Image Using a Generative Adversarial Network-Based Algorithm	210
Drone- and Paper-Based Analytical Devices: A Powerful Combination for the Colorimetric Detection of Tropospheric Ozone	205
Disruption Dynamics and Charge Transfer of a Single Attoliter Emulsion Droplet Revealed by Combined Fast-Scan Sinusoidal Voltammetry and Short Time Fourier Transform Analysis	184
Laser-Induced Thermophoretic SERS Enhancement on Paper for Facile Pesticide and Nanoplastic Sensing	183
A Dual-Structured Chromogenic Enzyme Platform for a Rapid, Sensitive, Durable, and Precise Gene Expression Analysis	178
Detection of Exchangeable Protons in NMR Metabolomic Analysis Using AI-Designed Water Irradiation Devoid Pulses	176
A Bacteria-Responsive Multifunctional Nanohydrogel for Recognition of Bacterial Infections and Activable Four-in-One Antibacterial Therapy	173
Near-Infrared Spectral Evidence for Water Structures in Icing by Chemometrics and Simulation	170
Microfluidic-Derived Detection of Protein-Facilitated Copper Flux Across Lipid Membranes	169
Chloride-Mediated Peroxide-Free Photochemical Oxidation of Proteins (PPOP) in Mass Spectrometry-Based Structural Analysis	167
Enalomics: A Mass Spectrometry-Based Approach for Profiling, Identifying, and Semiquantifying Enals in Biological Samples	165
Enzymatic Cleavage-Mediated Extension Stalling Enables Accurate Recognition and Quantification of Locus-Specific Uracil Modification in DNA	164
Weakly Supervised Identification and Localization of Drug Fingerprints Based on Label-Free Hyperspectral CARS Microscopy	157
Data-Driven Version of Multiway Soft Independent Modeling of Class Analogy (N-Way DD-SIMCA): Theory and Application	156
Reconfiguration/Immobilization “Dual-Free” Self-Powered Multiplex Photoelectrochemical Strategy for Dual Magnetic Bead-Mediated Dimension Differentiate Type Complex Sample Assay	155
Antifouling Cyclic Peptide Nanotubes Combined with Rh–Ti₃C₂T_X Multifunctional Nanozyme for the Sensitive Detection of CA125 in Complex Biological Samples	154
DiffN Selection of Tandem Mass Spectrometry Precursors	147
Fluorescence-On Imaging of Reticulophagy Enabled by an Acidity-Reporting Solvatochromic Probe	144
Step Change in Improving the Accuracy of Nitrous Oxide Reference Materials for Underpinning Atmospheric Composition Measurements	141
A One-Dimensional Phase-Modulated (PM) NMR Experiment for Differentiating Spin Systems in Small Molecules Mixtures: With Application to Chiral Discrimination and Bicomponent Organic Systems	141
Droplet Surface Immunoassay by Relocation (D-SIRe) for High-Throughput Analysis of Cytosolic Proteins at the Single-Cell Level	140

Reconstruction of Glutathione Metabolism in the Neuronal Model of Rotenone-Induced Neurodegeneration Using Mass Isotopologue Analysis with Hydrophilic Interaction Liquid Chromatography-Zeno High-Resol	139
Rapid and Noninvasive Quantification of Capsid Gene Filling Level Using Water Proton Nuclear Magnetic Resonance	137
Integrated Top-Down and Bottom-Up Mass Spectrometry for Characterization of Diselenide Bridging Patterns of Synthetic Selenoproteins	132
Novel Near-Infrared Cyanine Dyes for DNA Sequencing	130
Single-Stranded Nucleic Acid-Induced Aggregation of Intrinsically Chiral Helical Gold Nanorods for Biosensing Applications	122
Melamine-Modified Metal–Organic Framework as Novel Electrochemiluminescence Enhancer for Single-Electrode Multiplex cTnI Immunosensor	122
Construction of a Three-Dimensional-Printed Immunosensing Platform Based on Smartphone Photothermal Signal Integration	121
Single-Cell Detection of Circulating Tumor Cells by a Proximity-Enabled Singlet-Oxygen Chemiluminescence Assay	121
Miniaturized Laser Probe for Exosome-Based Cancer Liquid Biopsy	120
Signal2signal: Pushing the Spatiotemporal Resolution to the Limit by Single Chemical Hyperspectral Imaging	119
Exploring the Aggregation Propensity of PHF6 Peptide Segments of the Tau Protein Using Ion Mobility Mass Spectrometry Techniques	118
Infrared Spectroscopy with Variable Decomposition Level Dual-Tree Complex Wavelet Transform for Quantification of Air Pollutants	116
Dynamic Resilience Assessment of Single Cells under Cyclic Mechanical Loading Reveals Chemotherapy-Induced Cytoskeletal Microdamage	112
Selective Chemometric Elimination of Co-Eluting Components in Chiral and Achiral Liquid Chromatographic Analyses	109
Real-Time Evaluation of Adhesion Processes and Glucose Response of Cancer Cells onto Phenylboronic Acid-Functionalized Films Monitored by Quartz Crystal Microbalance with Dissipation	109
Cascading Detection of Hydrogen Sulfide and N-Acetyltransferase 2 in Hepatocellular Carcinoma Cells Using a Two-Photon Fluorescent Probe	108
Triblock PolyA-Mediated Protein Biosensor Based on a Size-Matching Proximity Hybridization Analysis	105
Label-Free SERS Sensors for Real-Time Monitoring of Tyrosine Phosphorylation	105
Analysis of Host Cell Proteins in AAV Products with ProteoMiner Protein Enrichment Technology	104
Sensitive Cancer Hypoxia Detection via a Dual-Locking Fluorescence Response System Using Two Hypoxia Indicators	101
An RCA-CRISPR-Enhanced SERS Platform for Ultrasensitive and Single-Nucleotide-Resolved Detection of Exosomal miRNA-21 in Early Lung Cancer	99
MobiLipid: A Tool for Enhancing CCS Quality Control of Ion Mobility–Mass Spectrometry Lipidomics by Internal Standardization	99
Real-Time Analysis of CO₂ Reduction Product Distribution by Synchrotron Vacuum Ultraviolet Photoionization Mass Spectrometry	99
pyMS-Vis, an Open-Source Python Application for Visualizing and Investigating Deconvoluted Top-Down Mass Spectrometric Experiments: A Histone Proteoform Case Study	99
Monitoring Bipolar Electrochemistry and Hydrogen Evolution Reaction of a Single Gold Microparticle under Sub-Micropipette Confinement	98
A High-Sensitive and Low-Probe-Dosage Nanoprobe for Quantifying Hydrogen Peroxide Fluctuations in Physiological Pathways	97
Polarity-Driven Fluorescence Monitoring of Lipid Droplet Dynamics in Dry Eye Disease	96
Fast Liquid Chromatography Coupled with Tandem Mass Spectrometry for the Analysis of Vanillic and Syringic Acids in Ice Cores	96
Low-Frequency Raman Spectroscopy as an Avenue to Determine the Transition Temperature of β- and γ-Relaxation in Pharmaceutical Glasses	96
Comprehensive Coverage of Glycolysis and Pentose Phosphate Metabolic Pathways by Isomer-Selective Accurate Targeted Hydrophilic Interaction Liquid Chromatography-Tandem Mass Spectrometry Assay	95
In Situ Transformable Pro-nanotheranostic Platform for Activable Photoacoustic Imaging and Synergistic Photothermal/Chemodynamic Cancer Therapy	95
Ion Mobility-Mass Spectrometry and Collision-Induced Unfolding of Designed Bispecific Antibody Therapeutics	93
Recent Advances in the Glass Pipet: from Fundament to Applications	93
Efficient Labeling of Vesicles with Lipophilic Fluorescent Dyes via the Salt-Change Method	91
Matrix-Compatible Solid-Phase Microextraction Pin Coupled Directly to Mass Spectrometry using Probe Electrospray Ionization	91
PLANTA Protocol for the Direct Detection and Identification of Bioactive Compounds in Complex Mixtures via Combined NMR-HPTLC-Based Heterocovariance	91
Probing Protein Structural Changes in Alzheimer’s Disease via Quantitative Cross-linking Mass Spectrometry	91
New-Typed Co₃O₄@Co–Fe Oxide/AuNPs Double Nanoboxes Nanozyme Enables Bimodal Monitoring Metallothioneins	91
Image Sensing of Gaseous Acetone Using Secondary Alcohol Dehydrogenase-Immobilized Mesh for Exhaled Air	90
Electrochemical Genosensing of Overexpressed GAPDH Transcripts in Breast Cancer Exosomes	90
Comprehensive and Site-Specific Characterization of Protein N-Glycosylation in AD Samples Reveals Its Potential Roles in Protein Aggregation and Synaptic Dysfunction	90
Three-Metal Oxide Hollow Lamellar Cube and Oxygen Vacancy Engineering: Construction of a Dual-Mode Sensing Platform and Collaborative Detection Mechanism	90
Smart Target-Initiated Catalytic DNA Junction Circuit Amplification Strategy for the Ultrasensitive Electrochemiluminescence Detection of MicroRNA	88
Isolation of High-Molecular-Weight DNA for Long-Read Sequencing Using a High-Salt Gel Electroelution Trap	88
Advances in Derivatization Techniques Enabled by DABCO for Novichok Agent Analysis in Biofluids Using LC–MS	87
Highly Active Single-Atom Nanozymes with High-Loading Iridium for Sensitive Detection of Pesticides	86
Trapping of Micro- and Nanoparticles within Microfluidic Constrictions in AC Electric Fields	86
Multimode Sensing Platform Based on Turn-On Fluorescent Silicon Nanoparticles for Monitoring of Intracellular pH and GSH	85
Mass Spectrometry Imaging of Lipids Using MALDI Coupled with Plasma-Based Post-Ionization on a Trapped Ion Mobility Mass Spectrometer	85
Toward Minute-Level DNA Computing: An Ultrafast, Cost-Effective, and Universal System for Lighting Up Various Concurrent DNA Logic Nanodevices (CDLNs) and Concatenated Circuits	85

Combined Morphological and Spectroscopic Diagnostic of HER2 Expression in Breast Cancer Tissues Based on Label-Free Surface-Enhanced Raman Scattering	84
Cell Response to Nanoplastics and Their Carrier Effects Tracked Real-Timely with Machine Learning-Driven Smart Surface-Enhanced Raman Spectroscopy Slides	84
Quantum Cascade Laser-Based Vibrational Circular Dichroism Augmented by a Balanced Detection Scheme	84
Few-Shot Learning-Based, Long-Term Stable, Sensitive Chemosensor for On-Site Colorimetric Detection of Cr(VI)	83
Enhanced Characterization of Histones Using 193 nm Ultraviolet Photodissociation and Proton Transfer Charge Reduction	83
Deep Learning-Based Classification of NSCLC-Derived Extracellular Vesicles Using AFM Nanomechanical Signatures	83
Do Anti-tuberculosis Drugs Reach Their Target?─High-Resolution Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Provides Information on Drug Penetration into Necrotic Granulomas	83
Conductive Covalent Organic Frameworks with Conductivity- and Pre-Reduction-Enhanced Electrochemiluminescence for Ultrasensitive Biosensor Construction	82
Dependence of Nonlinear Electrophoresis on Particle Size and Electrical Charge	82
Upconversion Luminescence-Initiated and GSH-Responsive Self-Driven DNA Motor for Automatic Operation in Living Cells and In Vivo	82
In Vivo Electrochemical Biosensors: Recent Advances in Molecular Design, Electrode Materials, and Electrochemical Devices	82