OOIR: Observatory of International Research

Papers

(The H4-Index of Analytical Chemistry is 80. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
In Situ SERS Monitoring and Heterogeneous Catalysis Verification of Pd-Catalyzed Suzuki–Miyaura Reaction via Bifunctional “Black Raspberry-like” Plasmonic Nanoreactors	318
A Dual-Structured Chromogenic Enzyme Platform for a Rapid, Sensitive, Durable, and Precise Gene Expression Analysis	288
Detection of Exchangeable Protons in NMR Metabolomic Analysis Using AI-Designed Water Irradiation Devoid Pulses	281
A Bacteria-Responsive Multifunctional Nanohydrogel for Recognition of Bacterial Infections and Activable Four-in-One Antibacterial Therapy	257
Metal-Mediated Polydopamine Nanoparticles–DNA Nanomachine Coupling Electrochemical Conversion of Metal–Organic Frameworks for Ultrasensitive MicroRNA Sensing	219
Carbon Nitride-Based Heterojunction Photoelectrodes with Modulable Charge-Transfer Pathways toward Selective Biosensing	203
Label-Free SERS Sensors for Real-Time Monitoring of Tyrosine Phosphorylation	198
Membrane-Free Lateral Flow Assay with the Active Control of Fluid Transport for Ultrasensitive Cardiac Biomarker Detection	185
Miniaturized Laser Probe for Exosome-Based Cancer Liquid Biopsy	171
Screening a DNA Aptamer Specifically Targeting Integrin β3 and Partially Inhibiting Tumor Cell Migration	165
Chloride-Mediated Peroxide-Free Photochemical Oxidation of Proteins (PPOP) in Mass Spectrometry-Based Structural Analysis	164
Enalomics: A Mass Spectrometry-Based Approach for Profiling, Identifying, and Semiquantifying Enals in Biological Samples	163
Tile-Based Pairwise Analysis of GC × GC-TOFMS Data to Facilitate Analyte Discovery and Mass Spectrum Purification	161
Microfluidic-Derived Detection of Protein-Facilitated Copper Flux Across Lipid Membranes	159
Amplified Biosensors Powered by Endogenous Molecules for Intracellular Fluorescence Imaging	158
Quantitatively Tracking the Speciation and Dynamics of Selenium Nanoparticles in Rice Plants	151
Near-Infrared Spectral Evidence for Water Structures in Icing by Chemometrics and Simulation	148
Endogenous Free-Electron-Involved Coreactant-Free Electrochemiluminescence from Nanoclusters and Its Immunoassay Application	145
Poly(glycidyl methacrylate-co-ethylene glycol dimethacrylate) Monolith with Dual Porosity for Size Exclusion Chromatography	143
Fluorescence-On Imaging of Reticulophagy Enabled by an Acidity-Reporting Solvatochromic Probe	138
A One-Dimensional Phase-Modulated (PM) NMR Experiment for Differentiating Spin Systems in Small Molecules Mixtures: With Application to Chiral Discrimination and Bicomponent Organic Systems	137
Characterization of Higher Order Structural Changes of a Thermally Stressed Monoclonal Antibody via Mass Spectrometry Footprinting and Other Biophysical Approaches	136
Dynamic Monitoring of Biomolecular Hydrodynamic Dimensions by Magnetization Motion on Quartz Crystal Microbalance	131
Step Change in Improving the Accuracy of Nitrous Oxide Reference Materials for Underpinning Atmospheric Composition Measurements	130
Droplet Surface Immunoassay by Relocation (D-SIRe) for High-Throughput Analysis of Cytosolic Proteins at the Single-Cell Level	128

Insights into the Main Protease of SARS-CoV-2: Thermodynamic Analysis, Structural Characterization, and the Impact of Inhibitors	128
Evaluation of a Novel Femtosecond Laser Ablation System for In Situ Analysis Based on Two-Dimensional Galvanometer Scanners	124
Reconstruction of Glutathione Metabolism in the Neuronal Model of Rotenone-Induced Neurodegeneration Using Mass Isotopologue Analysis with Hydrophilic Interaction Liquid Chromatography-Zeno High-Resol	124
Metal Organic Framework Nanomaterial-Based Extraction and Proteome Analysis of Membrane and Membrane-Associated Proteins	123
Linear Cryogel Arrays: On the Fast Track for Borreliosis Detection	121
Low-Frequency Raman Spectroscopy as an Avenue to Determine the Transition Temperature of β- and γ-Relaxation in Pharmaceutical Glasses	119
Fast Liquid Chromatography Coupled with Tandem Mass Spectrometry for the Analysis of Vanillic and Syringic Acids in Ice Cores	119
Molecular Design of Monochromophore-Based Bifunctional Photosensitizers for Simultaneous Ratiometric Oxygen Reporting and Photodynamic Cancer Therapy	119
Acyl-CoA Identification in Mouse Liver Samples Using the In Silico CoA-Blast Tandem Mass Spectral Library	118
Rapid and Noninvasive Quantification of Capsid Gene Filling Level Using Water Proton Nuclear Magnetic Resonance	112
Integrated Top-Down and Bottom-Up Mass Spectrometry for Characterization of Diselenide Bridging Patterns of Synthetic Selenoproteins	110
A Bio-inspired Extended-Gate Metal-Oxide-Semiconductor Field-Effect-Transistor for Highly Sensitive Amino Acid Enantiodiscrimination	110
DiffN Selection of Tandem Mass Spectrometry Precursors	110
Development and Preclinical Study of Free Radical Imaging Using Field-Cycling Dynamic Nuclear Polarization MRI	110
Direct Energy Transfer from a pH Glass Electrode to a Liquid Crystal Display	109
Smart Target-Initiated Catalytic DNA Junction Circuit Amplification Strategy for the Ultrasensitive Electrochemiluminescence Detection of MicroRNA	106
In Silico Study on a Binding Mechanism of ssDNA Aptamers Targeting Glycosidic Bond-Containing Small Molecules	105
Macrophage-Inspired Degradation-Activation System Enables Ultrasensitive Multicolor Detection of Haloacetic Acids via Janus Perovskite Halide Exchange	104
Fast Chemical Contrast by X-ray Fluorescence Intensity Ratio Detection	101
Lewis Acidic Metal–Organic Framework Assisted Ambient Liquid Extraction Mass Spectrometry Imaging for Enhancing the Coverage of Poorly Ionizable Lipids in Brain Tissue	100
Aminopeptidase N-Triggered Electron Rearrangement of Fluorescein for Covalent Fluorescent Labeling and Image-Guided Orthotopic Bladder Cancer Resection	99
Reconfiguration/Immobilization “Dual-Free” Self-Powered Multiplex Photoelectrochemical Strategy for Dual Magnetic Bead-Mediated Dimension Differentiate Type Complex Sample Assay	98
Signal2signal: Pushing the Spatiotemporal Resolution to the Limit by Single Chemical Hyperspectral Imaging	97
Development of a Recombinase-Aided Amplification Assay for the Rapid Detection of Candida auris	97
Trapping of Micro- and Nanoparticles within Microfluidic Constrictions in AC Electric Fields	97
Utilization of Machine Learning for the Differentiation of Positional NPS Isomers with Direct Analysis in Real Time Mass Spectrometry	96
Optimization of the Sulfo-Phospho-Vanillin Assay for Total Lipid Normalization in Untargeted Quantitative Lipidomic LC–MS/MS Applications	96
Sample-to-Answer Robotic ELISA	95
Quantitative and Multiplexed Chopper-Based Time-Gated Imaging for Bioanalysis on a Smartphone	95
Device-Physics Realization of ZnO–MWCNT Nanostructure-Based Field-Effect Biosensor for Ultrasensitive Simultaneous Genomic Detection of Foodborne Pathogens	94
Advances in Derivatization Techniques Enabled by DABCO for Novichok Agent Analysis in Biofluids Using LC–MS	93
An Off–On Fluorescent Probe Reveals Spatiotemporal Signaling of Opioid Receptors In Vivo for Pain Control	92
High-Sensitivity Detection of Oxygen Impurities in Glow Discharge Polymers through Non-Rutherford Resonance Backscattering	92
Rapid Hyperspectral Photothermal Mid-Infrared Spectroscopic Imaging from Sparse Data for Gynecologic Cancer Tissue Subtyping	91
Use of Transmission Electron Microscopy for Analysis of Aerosol Particles and Strategies for Imaging Fragile Particles	91
Advanced Mid-Infrared Sensors for Molecular Analysis	91
Novel Isotope-Labeled Derivatization Strategy for the Simultaneous Analysis of Fatty Acids and Fatty Alcohols and Its Application in Idiopathic Inflammatory Myopathies and Pancreatic Cancer	90
Probing Protein Structural Changes in Alzheimer’s Disease via Quantitative Cross-linking Mass Spectrometry	89
Dense and Acidic Organelle-Targeted Visualization in Living Cells: Application of Viscosity-Responsive Fluorescence Utilizing Restricted Access to Minimum Energy Conical Intersection	88
Ion Mobility-Mass Spectrometry and Collision-Induced Unfolding of Designed Bispecific Antibody Therapeutics	88
Deployment of MIL-88B(Fe)/TiO₂ Nanotube-Supported Ti Wires as Reusable Electrochemiluminescence Microelectrodes for Noninvasive Sensing of H₂O₂ from Single Cancer Cell	88
Divide and Conquer: A Flexible Deep Learning Strategy for Exploring Metabolic Heterogeneity from Mass Spectrometry Imaging Data	87
Investigation of the Electrocatalytic Reduction of Peroxydisulfate Using Scanning Electrochemical Microscopy	86
Comparison of Lanthanide Macrocyclic Complexes as ²³Na NMR Sensors	85
Triblock PolyA-Mediated Protein Biosensor Based on a Size-Matching Proximity Hybridization Analysis	84
Growth Characteristic Analysis of Haematococcus pluvialis in a Microfluidic Chip Using Digital in-Line Holographic Flow Cytometry	84
pyMS-Vis, an Open-Source Python Application for Visualizing and Investigating Deconvoluted Top-Down Mass Spectrometric Experiments: A Histone Proteoform Case Study	84
Laser-Induced Thermophoretic SERS Enhancement on Paper for Facile Pesticide and Nanoplastic Sensing	84
Segment Scan Mass Spectral Acquisition for Increasing the Metabolite Detectability in Chemical Isotope Labeling Liquid Chromatography–Mass Spectrometry Metabolome Analysis	83
Point-of-Care Diagnosis of Tuberculosis Using a Portable Nucleic Acid Test with Distance-Based Readout	83

Quartz Crystal Microbalance Frequency Response to Discrete Adsorbates in Liquids	82
Feasibility of Applying Fourier Transform Electrochemical Impedance Spectroscopy in Fast Cyclic Square Wave Voltammetry for theIn VivoMeasurement of Neurotransmitters	81
Self-Illuminating Copper-Luminol Coordination Polymers for Bioluminescence Imaging of Oxidative Damage	81
Dual-Mode Label with Dynamic Cracking–Wrinkling Pattern and Ultralong-Lifetime Phosphorescence for Multilevel Anti-counterfeiting and Time-Resolved Message Encryption Applications	80
Cell Response to Nanoplastics and Their Carrier Effects Tracked Real-Timely with Machine Learning-Driven Smart Surface-Enhanced Raman Spectroscopy Slides	80
Combined Morphological and Spectroscopic Diagnostic of HER2 Expression in Breast Cancer Tissues Based on Label-Free Surface-Enhanced Raman Scattering	80