OOIR: Observatory of International Research

Papers

(The H4-Index of Analytical Chemistry is 81. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
A Dual-Structured Chromogenic Enzyme Platform for a Rapid, Sensitive, Durable, and Precise Gene Expression Analysis	319
Detection of Exchangeable Protons in NMR Metabolomic Analysis Using AI-Designed Water Irradiation Devoid Pulses	299
A Bacteria-Responsive Multifunctional Nanohydrogel for Recognition of Bacterial Infections and Activable Four-in-One Antibacterial Therapy	225
Label-Free SERS Sensors for Real-Time Monitoring of Tyrosine Phosphorylation	206
Near-Infrared Spectral Evidence for Water Structures in Icing by Chemometrics and Simulation	199
Quantitatively Tracking the Speciation and Dynamics of Selenium Nanoparticles in Rice Plants	194
Membrane-Free Lateral Flow Assay with the Active Control of Fluid Transport for Ultrasensitive Cardiac Biomarker Detection	177
Microfluidic-Derived Detection of Protein-Facilitated Copper Flux Across Lipid Membranes	171
Carbon Nitride-Based Heterojunction Photoelectrodes with Modulable Charge-Transfer Pathways toward Selective Biosensing	168
Chloride-Mediated Peroxide-Free Photochemical Oxidation of Proteins (PPOP) in Mass Spectrometry-Based Structural Analysis	168
Screening a DNA Aptamer Specifically Targeting Integrin β3 and Partially Inhibiting Tumor Cell Migration	167
Enalomics: A Mass Spectrometry-Based Approach for Profiling, Identifying, and Semiquantifying Enals in Biological Samples	164
Poly(glycidyl methacrylate-co-ethylene glycol dimethacrylate) Monolith with Dual Porosity for Size Exclusion Chromatography	162
Fluorescence-On Imaging of Reticulophagy Enabled by an Acidity-Reporting Solvatochromic Probe	159
A One-Dimensional Phase-Modulated (PM) NMR Experiment for Differentiating Spin Systems in Small Molecules Mixtures: With Application to Chiral Discrimination and Bicomponent Organic Systems	158
Characterization of Higher Order Structural Changes of a Thermally Stressed Monoclonal Antibody via Mass Spectrometry Footprinting and Other Biophysical Approaches	152
Step Change in Improving the Accuracy of Nitrous Oxide Reference Materials for Underpinning Atmospheric Composition Measurements	149
Droplet Surface Immunoassay by Relocation (D-SIRe) for High-Throughput Analysis of Cytosolic Proteins at the Single-Cell Level	143
Reconstruction of Glutathione Metabolism in the Neuronal Model of Rotenone-Induced Neurodegeneration Using Mass Isotopologue Analysis with Hydrophilic Interaction Liquid Chromatography-Zeno High-Resol	142
Evaluation of a Novel Femtosecond Laser Ablation System for In Situ Analysis Based on Two-Dimensional Galvanometer Scanners	140
Metal Organic Framework Nanomaterial-Based Extraction and Proteome Analysis of Membrane and Membrane-Associated Proteins	139
Linear Cryogel Arrays: On the Fast Track for Borreliosis Detection	138
Molecular Design of Monochromophore-Based Bifunctional Photosensitizers for Simultaneous Ratiometric Oxygen Reporting and Photodynamic Cancer Therapy	134
Low-Frequency Raman Spectroscopy as an Avenue to Determine the Transition Temperature of β- and γ-Relaxation in Pharmaceutical Glasses	133
Fast Liquid Chromatography Coupled with Tandem Mass Spectrometry for the Analysis of Vanillic and Syringic Acids in Ice Cores	131

Rapid and Noninvasive Quantification of Capsid Gene Filling Level Using Water Proton Nuclear Magnetic Resonance	128
Development and Preclinical Study of Free Radical Imaging Using Field-Cycling Dynamic Nuclear Polarization MRI	127
Integrated Top-Down and Bottom-Up Mass Spectrometry for Characterization of Diselenide Bridging Patterns of Synthetic Selenoproteins	125
DiffN Selection of Tandem Mass Spectrometry Precursors	124
Smart Target-Initiated Catalytic DNA Junction Circuit Amplification Strategy for the Ultrasensitive Electrochemiluminescence Detection of MicroRNA	121
Direct Energy Transfer from a pH Glass Electrode to a Liquid Crystal Display	121
Investigation of Zero-/High-Field Ion Mobility Orthogonal Separation Using a Hyphenated DMA–FAIMS System and Validation of the Two-Temperature Theory at Arbitrary Field for Tetraalkylammonium Salts in	119
Construction and Preliminary Evaluation of Two ¹⁸F-Labeled Radiopharmaceuticals for Myocardial Perfusion Imaging	114
Enhanced Characterization of Histones Using 193 nm Ultraviolet Photodissociation and Proton Transfer Charge Reduction	114
Feasibility of Applying Fourier Transform Electrochemical Impedance Spectroscopy in Fast Cyclic Square Wave Voltammetry for theIn VivoMeasurement of Neurotransmitters	113
Nanopore Analysis as a Tool for Studying Rapid Holliday Junction Dynamics and Analyte Binding	113
High-Field Asymmetric Waveform Ion Mobility Spectrometry Interface Enhances Parallel Reaction Monitoring on an Orbitrap Mass Spectrometer	112
Reincarnation of the Analytical Ultracentrifuge: Emerging Opportunities for Nanomedicine	112
Microfluidic Chip-Based Automatic System for Sequencing Patient-Derived Organoids at the Single-Cell Level	111
Enzymatic Cleavage-Mediated Extension Stalling Enables Accurate Recognition and Quantification of Locus-Specific Uracil Modification in DNA	106
Combined Morphological and Spectroscopic Diagnostic of HER2 Expression in Breast Cancer Tissues Based on Label-Free Surface-Enhanced Raman Scattering	106
Antifouling Gold-Inlaid BSA Coating for the Highly Efficient Capture of Circulating Tumor Cells	105
Using Digestion by IdeS Protease to Improve Quantification of Degradants in Monoclonal Antibodies by Non-Reducing Capillary Gel Electrophoresis	104
Cell Response to Nanoplastics and Their Carrier Effects Tracked Real-Timely with Machine Learning-Driven Smart Surface-Enhanced Raman Spectroscopy Slides	103
Analysis of Peptides and Proteins by Native and SDS Capillary Gel Electrophoresis Coupled to Electrospray Ionization Mass Spectrometry via a Closed-Circuit Coaxial Sheath Flow Reactor Interface	103
Ultrasensitive MicroRNA Photoelectric Assay Based on a Mimosa-like CdS-NiS/Au Schottky Junction	100
Cyclic Olefin Copolymer-Based Fixed-Target Sample Delivery Device for Protein X-ray Crystallography	100
Rapid Electrochemical Detection of Bacterial Sepsis in Cirrhotic Patients: A Microscaffold-Based Approach for Early Intervention	99
Toward Hyphenated In Situ Infrared and Raman Spectroscopies in Interfacial Electrochemistry	98
Weakly Supervised Identification and Localization of Drug Fingerprints Based on Label-Free Hyperspectral CARS Microscopy	98
Calixarene-Based Magnetic Nanosponge Decorating AgNPs for Rapid and Selective Surface-Enhanced Raman Scattering Analysis in Complex Samples	97
Performance Evaluation of Extraction Coatings with Different Sorbent Particles and Binder Composition	96
Isolation of High-Molecular-Weight DNA for Long-Read Sequencing Using a High-Salt Gel Electroelution Trap	96
Device-Physics Realization of ZnO–MWCNT Nanostructure-Based Field-Effect Biosensor for Ultrasensitive Simultaneous Genomic Detection of Foodborne Pathogens	96
High-Sensitivity Detection of Oxygen Impurities in Glow Discharge Polymers through Non-Rutherford Resonance Backscattering	94
An Off–On Fluorescent Probe Reveals Spatiotemporal Signaling of Opioid Receptors In Vivo for Pain Control	93
Novel Isotope-Labeled Derivatization Strategy for the Simultaneous Analysis of Fatty Acids and Fatty Alcohols and Its Application in Idiopathic Inflammatory Myopathies and Pancreatic Cancer	93
Advanced Mid-Infrared Sensors for Molecular Analysis	93
Probing Protein Structural Changes in Alzheimer’s Disease via Quantitative Cross-linking Mass Spectrometry	92
Divide and Conquer: A Flexible Deep Learning Strategy for Exploring Metabolic Heterogeneity from Mass Spectrometry Imaging Data	92
Dense and Acidic Organelle-Targeted Visualization in Living Cells: Application of Viscosity-Responsive Fluorescence Utilizing Restricted Access to Minimum Energy Conical Intersection	92
Ion Mobility-Mass Spectrometry and Collision-Induced Unfolding of Designed Bispecific Antibody Therapeutics	92
Comparison of Lanthanide Macrocyclic Complexes as ²³Na NMR Sensors	90
Investigation of the Electrocatalytic Reduction of Peroxydisulfate Using Scanning Electrochemical Microscopy	90
Growth Characteristic Analysis of Haematococcus pluvialis in a Microfluidic Chip Using Digital in-Line Holographic Flow Cytometry	89
Segment Scan Mass Spectral Acquisition for Increasing the Metabolite Detectability in Chemical Isotope Labeling Liquid Chromatography–Mass Spectrometry Metabolome Analysis	89
Reconfiguration/Immobilization “Dual-Free” Self-Powered Multiplex Photoelectrochemical Strategy for Dual Magnetic Bead-Mediated Dimension Differentiate Type Complex Sample Assay	88
Point-of-Care Diagnosis of Tuberculosis Using a Portable Nucleic Acid Test with Distance-Based Readout	88
Fast Chemical Contrast by X-ray Fluorescence Intensity Ratio Detection	86
Aminopeptidase N-Triggered Electron Rearrangement of Fluorescein for Covalent Fluorescent Labeling and Image-Guided Orthotopic Bladder Cancer Resection	86
Optimization of the Sulfo-Phospho-Vanillin Assay for Total Lipid Normalization in Untargeted Quantitative Lipidomic LC–MS/MS Applications	85
In Silico Study on a Binding Mechanism of ssDNA Aptamers Targeting Glycosidic Bond-Containing Small Molecules	84
Macrophage-Inspired Degradation-Activation System Enables Ultrasensitive Multicolor Detection of Haloacetic Acids via Janus Perovskite Halide Exchange	83
CRISPR-Cas12a/Cas13a Multiplex Bioassay for ctDNA and miRNA by Mass Spectrometry	83
Measurement and Theory of Gas-Phase Ion Mobility Shifts Resulting from Isotopomer Mass Distribution Changes	83

Decoding the Assembly of Mixed and Branched Heterotypic Ubiquitin Chains	82
In Situ Selective Determination of Cysteine in Crops Employing a Novel Colorimetric and NIR-Emitting Ratiometric Fluorescent Probe along with a Smartphone-Assisted Portable Detection Device	82
Vesicle Impact Electrochemical Cytometry to Determine Carbon Nanotube-Induced Fusion of Intracellular Vesicles	82
Quantitative Analysis and 2D/3D Elemental Imaging of Cocoa Beans Using X-ray Fluorescence Techniques	81
D-π-A-Based Trisubstituted Alkenes as Environmentally Sensitive Fluorescent Probes to Detect Lewy Pathologies	81
Fully Automated CRISPR-LAMP Platform for SARS-CoV-2 Delta and Omicron Variants	81