Annals of Internal Medicine

Article	Citations
In rheumatic heart disease–associated AF, rivaroxaban increased adverse vascular outcomes vs. VKA at 3 y	292
Annals for Educators - October 2022	280
Aspirin use is associated with reduced risk for hepatocellular carcinoma	200
In type 2 diabetes, tirzepatide reduced HbA1c vs. semaglutide	177
Moving Beyond Race-Based Medicine	173
Life Lens	161
In suspected or provisionally diagnosed ACS, early CTCA did not reduce mortality or nonfatal MI at 1 y	160
In persons aged ≥45 y, the mt-sRNA test had 94% sensitivity for colorectal cancer and 46% for advanced adenomas	158
Annals Graphic Medicine - The COVID-19 Pandemic: A Graphic Narrative	151
Summary for Patients: Do Gastric Bypass and Sleeve Gastrectomy Help Reduce Liver Fat Content and Scarring in Patients With Type 2 Diabetes?	145
Summary for Patients: Metformin Use in the First Trimester of Pregnancy and Risk for Nonlive Birth and Congenital Malformations	143
Civility, 1968	140
Cost-Effectiveness of Screening Mammography Beyond Age 75 Years	137
Race/Ethnicity Trends Among U.S. Internal Medicine Residency Applicants and Matriculants: A Cross-Sectional Study	135
In patients with acute MI, spironolactone did not reduce cardiac events at 3 y	130
A Calling No Longer? When Medicine Is Redefined as a Job	130
ACP Updates Family and Medical Leave Policy	126
Bridging the Divide	125
Effectiveness of Adding a Mask Recommendation to Other Public Health Measures	123
Moving Stroke Rehabilitation Forward and Into the Future	118
Patients surviving COVID-19 had lower risk for long COVID in the Omicron vs. earlier eras	115
An intensivist-led telemedicine strategy did not reduce ICU LOS vs. usual care in critically ill patients	114
Trends in Concurrent Opioid and Benzodiazepine Prescriptions in the United States, 2016 to 2019	114
Short-Term Adverse Outcomes After Mifepristone–Misoprostol Versus Procedural Induced Abortion	111
In T2DM, periconceptional, noninsulin, second-line antidiabetes medications were not linked to major congenital malformations vs. insulin	108

Annals Video Summary - Effectiveness of Opioid Analgesic Medicines Prescribed in or at Discharge From Emergency Departments for Musculoskeletal Pain	107
In noncardiac thoracic surgery, low-dose colchicine did not reduce AF or myocardial injury after noncardiac surgery at 14 d	106
Little Miracles	106
Effectiveness of the 2023-to-2024 XBB.1.5 COVID-19 Vaccines Over Long-Term Follow-up	105
The Development of Living, Rapid Practice Points: Summary of Methods From the Scientific Medical Policy Committee of the American College of Physicians	104
Benefits and Risks Associated With Statin Therapy for Primary Prevention in Old and Very Old Adults	102
In menopause-related moderate-to-severe vasomotor symptoms not suitable for hormone therapy, fezolinetant safely improved symptoms	100
Understanding the Varying Biological Behaviors of Breast and Other Types of Cancer to Avoid Overdiagnosis	99
Challenging the Myths of the Against Medical Advice Discharge	93
K Awards: The Journey of a Thousand Steps	91
Inaccuracy of Pneumonia Diagnosis: The More Things Change, the More They Stay the Same	90
A Salty Odyssey: A Potassium-Enriched Journey Inspired by Don Quijote	90
Estimation of Breast Cancer Overdiagnosis in a U.S. Breast Screening Cohort	88
Hit Me With Your Best Shot: Long-Acting Therapies to Improve HIV Viral Suppression	86
After ACS, telemedicine-based care with remote patient monitoring vs. usual care reduced hospital readmissions at 6 mo	86
2022 Clinical Practice Guideline Update for Diabetes Management of Chronic Kidney Disease: An Important First Step, More Work to Do	86
Stories and Statistics	86
Long-Term Risk for Major Bleeding During Extended Oral Anticoagulant Therapy for First Unprovoked Venous Thromboembolism	85
Annals On Call - Surgery for Mild PTH	85
Evolving Practice Choices by Newly Certified and More Senior General Internists	84
Annals for Hospitalists Inpatient Notes - Clinical Pearls—Acute Pain Episodes in Sickle Cell Disease	83
Increasing Motivation for Lifestyle Change Is Not Enough to Treat Obesity	80
Prescription	77
New use of thiazide diuretics vs. nonthiazide antihypertensive drugs was linked to hyponatremia over 2 y	76
In H pylori infection, vonoprazan plus high-dose amoxicillin was noninferior to B-quadruple therapy for eradication	74
Factors Associated With Circulating Sex Hormones in Men	73
In the general population, salt substitutes vs. regular salt reduce BP levels, CV outcomes, and mortality	73
Effectiveness of Recombinant Zoster Vaccine Against Herpes Zoster in a Real-World Setting	72
The U.S. Founding Fathers Recognized the Benefits of Immunization—We Need That Same Recognition Today	72
Severe Maternal and Neonatal Morbidity Among Gestational Carriers	72
Safety and Efficiency of Diagnostic Strategies for Ruling Out Pulmonary Embolism in Clinically Relevant Patient Subgroups	71
Challenges in Estimating the Effectiveness of COVID-19 Vaccination Using Observational Data	70
In adults aged 50 to 69 y, invitation to screening with FIT was noninferior to invitation for colonoscopy for colorectal cancer mortality at 10 y	70
Reducing the Over-Diagnosis of Thyroid Disease	68
ACP provided strong and conditional recommendations for drug treatment in outpatients with acute episodic migraine	66
Annals for Hospitalists - January 2024	66
In acute episodic migraine attacks, triptans, with or without NSAIDs, vs. NSAIDs alone reduce pain at 2 h and up to 48 h	65
Annals Video Summary - Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes	63
Annals Video Summary - The Effect of Practitioner Empathy on Patient Satisfaction	62
Annals Story Slam - Loss of a Best Friend	62
The Use of Opioids in the Management of Chronic Pain	62
Prevalence and Management of Obesity in U.S. Adults With Type 1 Diabetes	62
Medical Masks Versus N95 Respirators for Preventing COVID-19 Among Health Care Workers	62
Annals Consult Guys - Care of a Patient With Left Ventricular Thrombus	60
Improvements in Cardiometabolic Risk Factors by Weight Reduction: A Post Hoc Analysis of Adults With Obesity Randomly Assigned to Tirzepatide	59
Annals Video Summary - Effect of Yoga on Frailty in Older Adults: A Systematic Review	59
The Rise of Psilocybin Use in the United States: A Multisource Observational Study	59
Medical Masks Versus N95 Respirators for Preventing COVID-19 Among Health Care Workers	59
Annals Video Summary - Bleeding Risks With Non–Vitamin K Oral Anticoagulants Versus Single Antiplatelet Therapy	58
Fecal Microbiota Transplantation Versus Vancomycin for Primary Clostridioides difficile Infection	58

Outpatient Treatment of Confirmed COVID-19: A Living, Rapid Evidence Review for the American College of Physicians (Version 2, Update Alert)	58
Correction: Efficacy of Acupuncture for Chronic Spontaneous Urticaria	57
Moving Beyond Race-Based Medicine	57
Annals Graphic Medicine - Dive	56
Bedside Manner	56
Correction: Accuracy of Ultrasound Jugular Venous Pressure Height in Predicting Central Venous Congestion	56
In adults receiving mechanical ventilation, selective decontamination of the digestive tract reduces hospital mortality	55
Annals for Educators - June 2022	55
Lifting the Illusion	55
In acute decompensated HF, adding acetazolamide to IV loop diuretics reduced congestion at 3 d	54
In prediabetes, oral vitamin D reduces progression to new-onset diabetes	54
Star Stuff	54
Comfort Measures Only	53
Ideation	53
Late in the Afternoon	53
Annals for Educators - February 2022	53
Annals Graphic Medicine - Dr. Mom: Which Presenter Are You?	52
In RA, use of systemic glucocorticoids ≥5 mg/d (prednisolone-equivalent) was linked to MACE at 8.7 y	52
Annals Story Slam - Future I.M. Experience: Resilience During COVID-19	52
Summary for Patients: Hydroxychloroquine Dose and Risk for Incident Retinopathy	52
Annals On Call - Bedside Rounds: The Patient Experience	51
Function and Frailty: Value Added in Medicare	51
In adults with TBI and anemia, liberal vs. restrictive RBC transfusion did not reduce unfavorable neurologic outcomes by 10% at 6 mo	50
In adults with kidney failure, hemodiafiltration vs. hemodialysis reduces all-cause and CV mortality	50
The Reign of the Ventilator: Acute Respiratory Distress Syndrome, COVID-19, and Technological Imperatives in Intensive Care	50
In older inpatients with polypharmacy, medication optimization did not improve outcomes at 48 wk	50
Detection of Tropheryma whipplei Genome From the Aqueous Humor by Metagenomic Sequencing	49
In paroxysmal AF, first-line catheter ablation vs. antiarrhythmic drugs reduces atrial arrhythmia recurrence	49
In non–critically ill patients with COVID-19, therapeutic anticoagulation improved survival to discharge without organ support	49
Values and Preferences of Patients With Depressive Disorders Regarding Pharmacologic and Nonpharmacologic Treatments	48
The Benefits and Risks of Receiving Investigational Solid Tumor Drugs in Randomized Trials	48
Diagnostic Strategies for the Assessment of Suspected Stable Coronary Artery Disease	48
Atrial Fibrillation Recurrence in Patients With Transient New-Onset Atrial Fibrillation Detected During Hospitalization for Noncardiac Surgery or Medical Illness	48
Oncology: What You May Have Missed in 2023	47
In ASCVD, an inclisiran-first strategy reduced LDL-C levels and statin discontinuation at 330 d	47
Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder: A Living Clinical Guideline From the American College of Physicians	47
Annals for Hospitalists Inpatient Notes - The Future of Hospital-at-Home Care	47
Untangling the Benefits of Time-Restricted Eating: Is It the Calories or the Time Restriction?	47
The Price of Admission	47
Achievement of Guideline-Recommended Targets in Diabetes Care in China	47
SGLT2 inhibitors reduce adverse renal and CV outcomes in patients with or without diabetes	46
Annals On Call - Understanding Benign Neutropenia	46
Beyond the Bacillus: Closing Gaps in Tuberculosis Health Disparities Requires Targeting Social Determinants	45
Lightning: Another Climate Change Threat	45
The More Things Change, the More They Stay the Same: Understanding the Safety of Outpatient Care	45
How Would You Treat This Patient With Acute and Chronic Pain From Sickle Cell Disease?	45
Contact Tracing and Exposure Investigation in Response to the First Case of Monkeypox Virus Infection in the United States During the 2022 Global Monkeypox Outbreak	45
Doctoring With a Double Disability	45
Science v. Ideology in Court: Mifepristone and the U.S. Food and Drug Administration	44
Accuracy of Ultrasound Jugular Venous Pressure Height in Predicting Central Venous Congestion	44
Change in Per Capita Opioid Prescriptions Filled at Retail Pharmacies, 2008–2009 to 2017–2018	44
The Effect of Open-Label Semaglutide on Metabolic Dysfunction–Associated Steatotic Liver Disease in People With HIV	43
Diabetes Risk Factors in People With HIV Receiving Pitavastatin Versus Placebo for Cardiovascular Disease Prevention	42
Associations of Serum Testosterone and Sex Hormone–Binding Globulin With Incident Cardiovascular Events in Middle-Aged to Older Men	42
Risk for Bleeding-Related Hospitalizations During Use of Amiodarone With Apixaban or Rivaroxaban in Patients With Atrial Fibrillation	42
The Problem of Aducanumab for the Treatment of Alzheimer Disease	41
Time-Restricted Eating Without Calorie Counting for Weight Loss in a Racially Diverse Population	40
Deep Venous Thrombosis	40
Long COVID Definitions and Models of Care	40
A Risk Profile Using Simple Hematologic Parameters to Assess Benefits From Baricitinib in Patients Hospitalized With COVID-19: A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-2	40
Telehealth Strategies for the Delivery of Maternal Health Care	40
Preparing the United States for the Next Pandemic	40
Assessing Heterogeneity of Treatment Effect in Real-World Data	40
Efficacy and Safety of Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss Among Adults Without Diabetes	40
Cardiometabolic Disease Burden and Steroid Excretion in Benign Adrenal Tumors	39
Artificial Intelligence–Assisted Colonoscopy for Polyp Detection	39
Prevalence and Characteristics of Adrenal Tumors in an Unselected Screening Population	39
Annals On Call - Encouraging Influenza Vaccination	38
Performance of the European Society of Cardiology 0/1-Hour, 0/2-Hour, and 0/3-Hour Algorithms for Rapid Triage of Acute Myocardial Infarction	38
Confirmatory Testing for Primary Aldosteronism	38
Annals Consult Guys - A Perplexing Case of Muscle Weakness	38
Annals Video Summary - Artificial Intelligence–Assisted Colonoscopy for Polyp Detection	37
Annals for Hospitalists - July 2024	37
Annals On Call - Health Expenditures of Patients With Diabetes After Bariatric Surgery	36
Medical, Societal, and Ethical Considerations for Directed Blood Donation in 2025	36
Annals for Hospitalists - December 2021	36
In COVID-19 acute hypoxemic respiratory failure, awake prone positioning vs. supine positioning increases survival without intubation	36
Annals for Educators - February 2023	36
In critically ill patients, preoxygenation with NIPPV or HFNC vs. face mask reduces hypoxemia during intubation	35
Annals On Call - Virtual Urgent Care: Artificial Intelligence Versus Physicians	35

Annals for Educators - June 2025	35
Visual Clinical Guideline - Newer Pharmacologic Treatments in Adults With Type 2 Diabetes: A Visual Clinical Guideline From the American College of Physicians	34
Time-Restricted Eating Without Calorie Counting for Weight Loss in a Racially Diverse Population	34
Forgiving Physician Debt	34
Annals Consult Guys - Noncardiac Surgery Following COVID-19: A Coast-to-Coast Update	34
Annals Graphic Medicine - 2 Face Comics Presents: Art Is the Best Medicine	34
How Would You Manage This Patient With Recurrent Diverticulitis?	34
Annals Graphic Medicine - Getting to a Place of Calm	34
Annals Graphic Medicine - The Things We Share	33
In ischemic left ventricular systolic dysfunction, adding PCI to medical therapy did not reduce death or HF hospitalization	33
Correction: Pharmacologic Treatment of Primary Osteoporosis or Low Bone Mass to Prevent Fractures in Adults	33
In type 1 diabetes, weekly basal insulin Fc was noninferior to daily insulin degludec for HbA1c at 26 wk	33
In older patients at high risk for stroke, intensive AF screening with an implantable loop recorder did not reduce stroke	33
In RA in remission for >1 y, tapering TNFi to discontinuation did not meet noninferiority criteria compared with stable TNFi for disease flare at 12 mo	33
Ensuring Adequate Preparation for Patient Care Through Interprofessional Team-Based Training and Postgraduate Residencies for Nonphysician Clinicians	33
SCCM issued recommendations for corticosteroid use in acutely ill adults with sepsis, ARDS, or CAP	32
Integrating Quality Assurance and Quality Improvement With Guidelines: Systematic Stakeholder-Driven Development of an Extension of the Guidelines International Network–McMaster Guideline Development	32
In drug-refractory IBS, group CBT with interoceptive exposure improved symptoms and QoL at 13 wk	32
In severe, uncontrolled asthma, tezepelumab reduced exacerbations and improved asthma control at 1 y	32
In IBS, a smartphone application for self-managing a FODMAP-lowering diet vs. otilonium bromide reduced symptoms at 8 wk	32
Annals Story Slam - I Know Them by Name	32
Effectiveness of Nirmatrelvir–Ritonavir Against the Development of Post–COVID-19 Conditions Among U.S. Veterans	32
Annals Graphic Medicine - More Than Skin Deep	31
In tobacco smokers with respiratory symptoms, a dual bronchodilator did not reduce symptoms at 12 wk	31
Correction: Resuming In-Person Learning	31
Annals Graphic Medicine - The Hospital Makes It Hard to Speak Up for Myself	31
Prayer Flags	31
Annals Graphic Medicine - Dr. Mom: Medical Conference	31
Correction: 15-Year Benefits of Sigmoidoscopy Screening on Colorectal Cancer Incidence and Mortality	31
Blood Pressure Level in Late Adolescence and Risk for Cardiovascular Events	30
In patients with chronic neuropathic pain, cannabinoids improve sleep and reduce pain vs. placebo	30
In patients with type 2 diabetes and recent MI, colchicine reduced a composite CV outcome at 23 mo	30
Living Practice Guidelines Require Robust and Continuous Iteration and Uptake	30
In AF, CHA2DS2-VASc 1 subgroups did not differ for predicting risk for arterial thromboembolism at 1 y	30
In type 2 diabetes, the BT-001 smartphone app reduced HbA1c more than a control app at 90 d	30
Guideline recommends buprenorphine or methadone as first-line treatment for opioid use disorder (high certainty)	30
In patients with subclinical AF, apixaban vs. aspirin reduced stroke or systemic embolism at 3.5 y in those with previous stroke or TIA	29
Summary for Patients: Fracture Risk During Osteoporosis Drug Holidays	29
The Health Benefits of Urgent Upstream Action on Climate Change	29
Endocrinology: What You May Have Missed in 2024	29
Summary for Patients: Postdiagnosis Smoking Cessation and Reduced Risk for Lung Cancer Progression and Death	29
Tofacitinib reduced death or respiratory failure at 28 d in patients hospitalized with COVID-19 pneumonia	29
Will QUADAS-C Make a Complicated Task Less Complex?	29
Correction: Diagnostic Discordance, Uncertainty, and Treatment Ambiguity in Community-Acquired Pneumonia	29
we are forgetting	29
Paternal Preconception Diabetes Drugs and Birth Defects in Offspring: A Call for More Conclusive Study	29
Suicide in U.S. Indigenous Persons: Reframing the Etiology and Solutions	28
Standardization and Prediction to Control Confounding: Estimating Risk Differences and Ratios for Clinical Interpretations and Decision Making	28
Effectiveness of Motivational Interviewing in Managing Overweight and Obesity	28
Best Practices in Caring for Seriously Ill Patients	28
U.S. State Medical Boards’ Antiracism Education Requirements for Physicians	28
In patients receiving invasive ventilation, PPIs reduce upper GI bleeding but did not affect mortality at 90 d	28
Building the Beloved (Health) Community: Antiracism, Diversity, and Primary Care	28
Bipolar Disorder	28
Primary Occurrence of Cardiovascular Events After Adding Sodium–Glucose Cotransporter-2 Inhibitors or Glucagon-like Peptide-1 Receptor Agonists Compared With Dipeptidyl Peptidase-4 Inhibitors: A Cohor	27
In adults with HIV and low-to-moderate CV risk, pitavastatin reduced MACE over a median 5.1 y	27
Telemedicine Uptake Among Older Adults During the COVID-19 Pandemic	27
Trends in Discharge Rates for Acute Pulmonary Embolism in U.S. Emergency Departments	27
Risk for Congenital Anomalies in Children Conceived With Medically Assisted Fertility Treatment	27
Factors Associated With Risk for Care Escalation Among Patients With COVID-19 Receiving Home-Based Hospital Care	27
Stroke Rehabilitation: Synopsis of the 2024 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guidelines	27
COVID-19 Inequities Across Multiple Racial and Ethnic Groups: Results From an Integrated Health Care Organization	27
Epidemiology of Coronary Atherosclerosis Among People Living With HIV in Uganda	27
Trends in Alcohol Use After the COVID-19 Pandemic: A National Cross-Sectional Study	27
Comparison of Rapid Antigen Tests' Performance Between Delta and Omicron Variants of SARS-CoV-2	27
Annals Graphic Medicine - Being There	26
Annals Video Summary - Attention Among Health Care Professionals: A Scoping Review	26
In adults aged 75 to 76 y, systematic AF screening reduced morbidity and mortality at 6 y	26
Outpatient Treatment of Confirmed COVID-19: Living, Rapid Practice Points From the American College of Physicians (Version 2, Update Alert)	26
Annals Video Summary - The Effect of SEP-1 Bundle Compliance and Implementation on Mortality Among Patients With Sepsis	26
Annals Graphic Medicine - Beyond the Numbers	26
Prediction of End-Stage Kidney Disease Using Estimated Glomerular Filtration Rate With and Without Race	26
Ankle Osteoarthritis: Successful Completion of a Challenging Clinical Trial Comparing Surgical Treatments	26
Annals Consult Guys - The ABCs of Atrial Fibrillation	26
Annals On Call - Diagnostic Reasoning Part 1	26
Annals Graphic Medicine - The Substance Use Epidemic: A Graphic Narrative	26
Annals Consult Guys - Surgery After Thromboembolic Stroke	26
Subclinical Coronary Atherosclerosis and Risk for Myocardial Infarction in a Danish Cohort	26
Annals Video Summary - Associations of Testosterone and Related Hormones With All-Cause and Cardiovascular Mortality and Incident Cardiovascular Disease in Men	26
COVID-19 Vaccination Effectiveness Against Infection or Death in a National U.S. Health Care System	26
Annals Consult Guys - The Case of the Restless Legs	26
In THA or TKA, risk for symptomatic VTE was higher with aspirin vs. enoxaparin at 90 d	25
In latent autoimmune diabetes in adults, mortality was similar to T2DM but retinopathy was higher at 5.9 y	25
In pregnant women with suspected VTE and low/intermediate or unlikely pretest probability, D-dimer rules out VTE at 3 mo	25
Summary for Patients: Mortality and Morbidity in Mild Primary Hyperparathyroidism	25
In migraine with previous treatment failures, eptinezumab safely reduced migraine days at 1 to 12 wk	25
Annals Consult Guys - Frailty: Its Role as a Risk Factor in Surgery	25
USPSTF found insufficient evidence on the benefits and harms of screening adults ≥50 y for AF	25
Affirmative Action Bans and Enrollment of Students From Underrepresented Racial and Ethnic Groups in U.S. Public Medical Schools	25
Summary for Patients: Benefits and Risks Associated With Statin Therapy for Primary Prevention in Old and Very Old Adults	24
Self-reflection on an Elevated BMI	24
Correction: Deep Learning to Estimate Cardiovascular Risk From Chest Radiographs	24
Correction: Point-of-Care Ultrasonography in Patients With Acute Dyspnea	24
Evaluation and Management After Acute Left-Sided Colonic Diverticulitis	24
In HF with mildly reduced or preserved ejection fraction, finerenone reduced worsening HF or CV death at 32 mo	24