Annals of Internal Medicine

Article	Citations
Annals Graphic Medicine - The COVID-19 Pandemic: A Graphic Narrative	323
Summary for Patients: Metformin Use in the First Trimester of Pregnancy and Risk for Nonlive Birth and Congenital Malformations	268
Civility, 1968	250
In rheumatic heart disease–associated AF, rivaroxaban increased adverse vascular outcomes vs. VKA at 3 y	220
Annals for Educators - October 2022	209
In persons aged ≥45 y, the mt-sRNA test had 94% sensitivity for colorectal cancer and 46% for advanced adenomas	206
In T2DM, periconceptional, noninsulin, second-line antidiabetes medications were not linked to major congenital malformations vs. insulin	203
Annals Video Summary - Bleeding Risks With Non–Vitamin K Oral Anticoagulants Versus Single Antiplatelet Therapy	173
In adults aged 50 to 69 y, invitation to screening with FIT was noninferior to invitation for colonoscopy for colorectal cancer mortality at 10 y	167
ACP provided strong and conditional recommendations for drug treatment in outpatients with acute episodic migraine	166
Annals for Hospitalists - January 2024	166
In acute episodic migraine attacks, triptans, with or without NSAIDs, vs. NSAIDs alone reduce pain at 2 h and up to 48 h	160
Annals Video Summary - Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes	159
Annals Story Slam - Loss of a Best Friend	159
Annals Video Summary - The Effect of Practitioner Empathy on Patient Satisfaction	146
The Use of Opioids in the Management of Chronic Pain	145
Medical Masks Versus N95 Respirators for Preventing COVID-19 Among Health Care Workers	145
Annals Consult Guys - Care of a Patient With Left Ventricular Thrombus	135
Medical Masks Versus N95 Respirators for Preventing COVID-19 Among Health Care Workers	133
Annals Video Summary - Effect of Yoga on Frailty in Older Adults: A Systematic Review	130
Annals Video Summary - Effectiveness of Opioid Analgesic Medicines Prescribed in or at Discharge From Emergency Departments for Musculoskeletal Pain	129
In patients with acute MI, spironolactone did not reduce cardiac events at 3 y	127
ACP Updates Family and Medical Leave Policy	123
Patients surviving COVID-19 had lower risk for long COVID in the Omicron vs. earlier eras	122
An intensivist-led telemedicine strategy did not reduce ICU LOS vs. usual care in critically ill patients	119

In carotid stenosis with low or intermediate risk for stroke, adding revascularization to OMT did not improve outcomes at 2 y	117
2022 Clinical Practice Guideline Update for Diabetes Management of Chronic Kidney Disease: An Important First Step, More Work to Do	112
Reducing the Over-Diagnosis of Thyroid Disease	105
In noncardiac thoracic surgery, low-dose colchicine did not reduce AF or myocardial injury after noncardiac surgery at 14 d	105
A Salty Odyssey: A Potassium-Enriched Journey Inspired by Don Quijote	104
Inaccuracy of Pneumonia Diagnosis: The More Things Change, the More They Stay the Same	103
Estimation of Breast Cancer Overdiagnosis in a U.S. Breast Screening Cohort	102
Stories and Statistics	91
Hit Me With Your Best Shot: Long-Acting Therapies to Improve HIV Viral Suppression	91
After ACS, telemedicine-based care with remote patient monitoring vs. usual care reduced hospital readmissions at 6 mo	89
Annals On Call - Surgery for Mild PTH	87
In menopause-related moderate-to-severe vasomotor symptoms not suitable for hormone therapy, fezolinetant safely improved symptoms	86
Benefits and Risks Associated With Statin Therapy for Primary Prevention in Old and Very Old Adults	86
New use of thiazide diuretics vs. nonthiazide antihypertensive drugs was linked to hyponatremia over 2 y	85
In CKD, electronic letter nudges for patients or providers did not increase RASi or SGLT2i prescriptions at 6 mo	84
Prescription	84
The U.S. Founding Fathers Recognized the Benefits of Immunization—We Need That Same Recognition Today	82
A Calling No Longer? When Medicine Is Redefined as a Job	81
Outpatient Treatment of Confirmed COVID-19: A Living, Rapid Evidence Review for the American College of Physicians (Version 2, Update Alert)	80
Little Miracles	79
In moderate to severe chronic breathlessness, low-dose, long-acting oral morphine did not improve worst breathlessness at 28 d	78
In patients with CAD, clopidogrel vs. aspirin monotherapy reduces MACCE without increasing major bleeding	77
In the general population, salt substitutes vs. regular salt reduce BP levels, CV outcomes, and mortality	77
In hypertension with high CV risk, intensive vs. standard BP-lowering therapy improved HRQoL by a small amount at a median 3.4 y	77
Prevention of Recurrent Nephrolithiasis in Adults and Children	76
Effectiveness of the 2023-to-2024 XBB.1.5 COVID-19 Vaccines Over Long-Term Follow-up	75
The Importance of the Childhood Immunization Schedule for Internal Medicine	73
Care of the Patient With Abnormal Kidney Test Results (Japanese Version)	73
In uncontrolled asthma, adding glycopyrronium to budesonide–formoterol reduced annualized severe exacerbations	71
Low-Volume Polyethylene Glycol for Bowel Preparation in Hospitalized Adults	70
In adults with acute VTE, apixaban vs. rivaroxaban reduced clinically relevant bleeding at 3 mo	69
Functional Status of Adults at Risk of Medicaid Disenrollment Under National Work Requirements	69
Adverse Events After Same-Day COVID-19 and Influenza Vaccination Versus Influenza Vaccination Alone	68
In H pylori infection, vonoprazan plus high-dose amoxicillin was noninferior to B-quadruple therapy for eradication	67
Moving Stroke Rehabilitation Forward and Into the Future	67
Short-Term Adverse Outcomes After Mifepristone–Misoprostol Versus Procedural Induced Abortion	66
Understanding the Varying Biological Behaviors of Breast and Other Types of Cancer to Avoid Overdiagnosis	66
Prevalence and Management of Obesity in U.S. Adults With Type 1 Diabetes	66
Fecal Microbiota Transplantation Versus Vancomycin for Primary Clostridioides difficile Infection	66
Factors Associated With Circulating Sex Hormones in Men	65
Chronic Coronary Artery Disease	63
Functional seizures tough to recognize	63
Improvements in Cardiometabolic Risk Factors by Weight Reduction: A Post Hoc Analysis of Adults With Obesity Randomly Assigned to Tirzepatide	62
The Rise of Psilocybin Use in the United States: A Multisource Observational Study	62
Comparison of Initial Artificial Intelligence (AI) and Final Physician Recommendations in AI-Assisted Virtual Urgent Care Visits	60
Effectiveness of Recombinant Zoster Vaccine Against Herpes Zoster in a Real-World Setting	60
Severe Maternal and Neonatal Morbidity Among Gestational Carriers	59
Challenges in Estimating the Effectiveness of COVID-19 Vaccination Using Observational Data	59
In acute decompensated HF, adding acetazolamide to IV loop diuretics reduced congestion at 3 d	58
In adults receiving mechanical ventilation, selective decontamination of the digestive tract reduces hospital mortality	57

Late in the Afternoon	57
Star Stuff	57
Annals Graphic Medicine - Dive	56
Bedside Manner	56
Correction: Efficacy of Acupuncture for Chronic Spontaneous Urticaria	55
Comfort Measures Only	55
Ideation	55
The Price of Admission	54
Annals On Call - Atrial Fibrillation: When Ablation Is the Way to Go	54
Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder: A Living Clinical Guideline From the American College of Physicians	54
The More Things Change, the More They Stay the Same: Understanding the Safety of Outpatient Care	53
Lightning: Another Climate Change Threat	53
Annals On Call - Understanding Benign Neutropenia	53
Beyond the Bacillus: Closing Gaps in Tuberculosis Health Disparities Requires Targeting Social Determinants	52
Science v. Ideology in Court: Mifepristone and the U.S. Food and Drug Administration	52
In adults with TBI and anemia, liberal vs. restrictive RBC transfusion did not reduce unfavorable neurologic outcomes by 10% at 6 mo	51
Function and Frailty: Value Added in Medicare	51
Oncology: What You May Have Missed in 2023	51
In adults with kidney failure, hemodiafiltration vs. hemodialysis reduces all-cause and CV mortality	51
Values and Preferences of Patients With Depressive Disorders Regarding Pharmacologic and Nonpharmacologic Treatments	51
Untangling the Benefits of Time-Restricted Eating: Is It the Calories or the Time Restriction?	50
Summary for Patients: Hydroxychloroquine Dose and Risk for Incident Retinopathy	50
In ASCVD, an inclisiran-first strategy reduced LDL-C levels and statin discontinuation at 330 d	50
In older inpatients with polypharmacy, medication optimization did not improve outcomes at 48 wk	50
Annals Consult Guys - A Perplexing Case of Muscle Weakness	50
In RA, use of systemic glucocorticoids ≥5 mg/d (prednisolone-equivalent) was linked to MACE at 8.7 y	50
Annals On Call - Health Expenditures of Patients With Diabetes After Bariatric Surgery	49
Annals for Hospitalists - July 2024	49
In COVID-19 acute hypoxemic respiratory failure, awake prone positioning vs. supine positioning increases survival without intubation	49
Annals On Call - Encouraging Influenza Vaccination	49
Annals for Educators - February 2023	49
Annals Video Summary - Artificial Intelligence–Assisted Colonoscopy for Polyp Detection	49
Annals On Call - Virtual Urgent Care: Artificial Intelligence Versus Physicians	48
In critically ill patients, preoxygenation with NIPPV or HFNC vs. face mask reduces hypoxemia during intubation	48
Time-Restricted Eating Without Calorie Counting for Weight Loss in a Racially Diverse Population	47
Annals Consult Guys - Noncardiac Surgery Following COVID-19: A Coast-to-Coast Update	47
Annals Graphic Medicine - 2 Face Comics Presents: Art Is the Best Medicine	47
Annals Graphic Medicine - Getting to a Place of Calm	47
Annals for Educators - June 2025	47
How Would You Manage This Patient With Recurrent Diverticulitis?	46
Annals for Hospitalists Inpatient Notes - The Future of Hospital-at-Home Care	46
Forgiving Physician Debt	46
Visual Clinical Guideline - Newer Pharmacologic Treatments in Adults With Type 2 Diabetes: A Visual Clinical Guideline From the American College of Physicians	45
In prediabetes, oral vitamin D reduces progression to new-onset diabetes	44
Q&A: Looking beyond the CDC	44
Beyond the Diagnosis: Finding the Person in the Patient	44
Preparing the United States for the Next Pandemic	44
SGLT2 inhibitors reduce adverse renal and CV outcomes in patients with or without diabetes	44
A Risk Profile Using Simple Hematologic Parameters to Assess Benefits From Baricitinib in Patients Hospitalized With COVID-19: A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-2	43
Integrating Methadone Services Into Primary Care in Ukraine: Two-Year Outcomes From a Randomized Trial	43
Talking With Patients About Health-Related Mis- and Disinformation	43
In postmenopausal women at high risk for fracture, romosozumab for 3 mo was noninferior to 12 mo for increasing total hip BMD at 1 y	43
Q&A: ACP focuses on appropriate screening for breast cancer	42
Atrial Fibrillation Recurrence in Patients With Transient New-Onset Atrial Fibrillation Detected During Hospitalization for Noncardiac Surgery or Medical Illness	42
In adults with predisposing conditions, diagnostic accuracy of RCE components for detecting volume overload varies	42
Achievement of Guideline-Recommended Targets in Diabetes Care in China	42
Prevalence and Characteristics of Adrenal Tumors in an Unselected Screening Population	41
Medical, Societal, and Ethical Considerations for Directed Blood Donation in 2025	41
Thyroid Function Reference Intervals by Age, Sex, and Race	41
Telehealth Strategies for the Delivery of Maternal Health Care	41
Confirmatory Testing for Primary Aldosteronism	41
Long COVID Definitions and Models of Care	41
Pragmatic Trials: The Importance of Foundational Research, Fidelity, Implementation, and Context	40
The Effect of Open-Label Semaglutide on Metabolic Dysfunction–Associated Steatotic Liver Disease in People With HIV	39
How Would You Manage This Patient With Idiopathic Acute Pancreatitis? Grand Rounds Discussion From Beth Israel Deaconess Medical Center	39
Annals Video Summary - The Role of Telemedicine on Interhospital Transfer Outcomes	39
Irritable Bowel Syndrome	39
Diagnostic Strategies for the Assessment of Suspected Stable Coronary Artery Disease	39
Contact Tracing and Exposure Investigation in Response to the First Case of Monkeypox Virus Infection in the United States During the 2022 Global Monkeypox Outbreak	39
Time-Restricted Eating Without Calorie Counting for Weight Loss in a Racially Diverse Population	38
The Benefits and Risks of Receiving Investigational Solid Tumor Drugs in Randomized Trials	38
Efficacy and Safety of Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss Among Adults Without Diabetes	38
Artificial Intelligence–Assisted Colonoscopy for Polyp Detection	38
Patient-Centered Prescription Opioid Tapering Methods	38
Assessing Heterogeneity of Treatment Effect in Real-World Data	37
The Legal and Ethical Framework for Artificial Intelligence in Gastrointestinal Endoscopy: A World Endoscopy Organization International Consensus Statement	37
Deep Venous Thrombosis	37
Bolstering the Medication Supply Chain and Ameliorating Medication Shortages: A Position Paper From the American College of Physicians	37
Risk for Bleeding-Related Hospitalizations During Use of Amiodarone With Apixaban or Rivaroxaban in Patients With Atrial Fibrillation	36
Diabetes Risk Factors in People With HIV Receiving Pitavastatin Versus Placebo for Cardiovascular Disease Prevention	36

In IBS, a smartphone application for self-managing a FODMAP-lowering diet vs. otilonium bromide reduced symptoms at 8 wk	36
Correction: Pharmacologic Treatment of Primary Osteoporosis or Low Bone Mass to Prevent Fractures in Adults	36
Endocrinology: What You May Have Missed in 2024	35
In type 1 diabetes, weekly basal insulin Fc was noninferior to daily insulin degludec for HbA1c at 26 wk	35
Ensuring Adequate Preparation for Patient Care Through Interprofessional Team-Based Training and Postgraduate Residencies for Nonphysician Clinicians	35
Dear Fellow Introverts	35
In ischemic left ventricular systolic dysfunction, adding PCI to medical therapy did not reduce death or HF hospitalization	35
Blood Pressure Level in Late Adolescence and Risk for Cardiovascular Events	34
Annals Graphic Medicine - Being There	34
Annals Video Summary - Attention Among Health Care Professionals: A Scoping Review	34
Correction: 15-Year Benefits of Sigmoidoscopy Screening on Colorectal Cancer Incidence and Mortality	34
Annals Consult Guys - The ABCs of Atrial Fibrillation	34
Annals Video Summary - Associations of Testosterone and Related Hormones With All-Cause and Cardiovascular Mortality and Incident Cardiovascular Disease in Men	34
Correction: Resuming In-Person Learning	34
Annals Consult Guys - Surgery After Thromboembolic Stroke	34
Annals Graphic Medicine - Beyond the Numbers	33
Prayer Flags	33
Annals On Call - Diagnostic Reasoning Part 1	33
Annals Graphic Medicine - The Substance Use Epidemic: A Graphic Narrative	33
Annals Consult Guys - The Case of the Restless Legs	33
Annals Video Summary - The Effect of SEP-1 Bundle Compliance and Implementation on Mortality Among Patients With Sepsis	33
In tobacco smokers with respiratory symptoms, a dual bronchodilator did not reduce symptoms at 12 wk	32
Epidemiology of Coronary Atherosclerosis Among People Living With HIV in Uganda	32
Subclinical Coronary Atherosclerosis and Risk for Myocardial Infarction in a Danish Cohort	32
Best Practices in Caring for Seriously Ill Patients	32
Living Practice Guidelines Require Robust and Continuous Iteration and Uptake	31
In adults with HIV and low-to-moderate CV risk, pitavastatin reduced MACE over a median 5.1 y	31
In type 2 diabetes, the BT-001 smartphone app reduced HbA1c more than a control app at 90 d	31
Trends in Alcohol Use After the COVID-19 Pandemic: A National Cross-Sectional Study	31
Primary Occurrence of Cardiovascular Events After Adding Sodium–Glucose Cotransporter-2 Inhibitors or Glucagon-like Peptide-1 Receptor Agonists Compared With Dipeptidyl Peptidase-4 Inhibitors: A Cohor	31
Correction to ACP Journal Club: Error in Commentary	31
In patients with ischemic stroke, NVAF, and ASCVD, adding an antiplatelet to OAC therapy did not affect net clinical benefit at 2 y	31
SCCM issued recommendations for corticosteroid use in acutely ill adults with sepsis, ARDS, or CAP	31
In drug-refractory IBS, group CBT with interoceptive exposure improved symptoms and QoL at 13 wk	31
In AF, CHA2DS2-VASc 1 subgroups did not differ for predicting risk for arterial thromboembolism at 1 y	31
Management of Hyperglycemia in Hospitalized Patients	30
Medical Journals: Slow Boats in Rough Seas	30
In patients with chronic neuropathic pain, cannabinoids improve sleep and reduce pain vs. placebo	30
Annals for Educators - December 2025	30
In mechanically ventilated, critically ill adults, conservative vs. usual supplemental oxygen did not reduce mortality at 90 d	30
In older, frail, VKA-experienced patients with AF, SD-DOACs vs. warfarin reduced thrombotic events without increasing major bleeding	30
Guideline recommends buprenorphine or methadone as first-line treatment for opioid use disorder (high certainty)	30
In patients receiving invasive ventilation, PPIs reduce upper GI bleeding but did not affect mortality at 90 d	29
Building the Beloved (Health) Community: Antiracism, Diversity, and Primary Care	29
Correction: Diagnostic Discordance, Uncertainty, and Treatment Ambiguity in Community-Acquired Pneumonia	29
In patients with subclinical AF, apixaban vs. aspirin reduced stroke or systemic embolism at 3.5 y in those with previous stroke or TIA	29
Effectiveness of Motivational Interviewing in Managing Overweight and Obesity	29
Suicide in U.S. Indigenous Persons: Reframing the Etiology and Solutions	29
In older adults, RSV prefusion F vaccine reduced hospitalization for RSV-related respiratory tract disease vs. no vaccine	28
The AABB and ICTMG issued recommendations on the restrictive use of platelet transfusions	28
Illuminating the Value of Palliative Care in Cancer	28
In older adults with impaired physical performance after MI, multidomain rehabilitation reduced CV death or CV hospitalization at 1 y	28
In adults hospitalized with acute HF, predischarge influenza vaccination reduced a composite of mortality or readmission at 1 y	28
Comparison of Rapid Antigen Tests' Performance Between Delta and Omicron Variants of SARS-CoV-2	27
Effectiveness of Nirmatrelvir–Ritonavir Against the Development of Post–COVID-19 Conditions Among U.S. Veterans	27
Outpatient Treatment of Confirmed COVID-19: Living, Rapid Practice Points From the American College of Physicians (Version 2, Update Alert)	27
Advancing Physical Function Outcomes in Glucagon-Like Peptide-1 Receptor Agonist Trials	27
In RA in remission for >1 y, tapering TNFi to discontinuation did not meet noninferiority criteria compared with stable TNFi for disease flare at 12 mo	26
Annals for Educators - June 2026	26
Addressing Primary Care Needs in People Living With Sickle Cell Disease	26
Trends in Discharge Rates for Acute Pulmonary Embolism in U.S. Emergency Departments	26
U.S. State Medical Boards’ Antiracism Education Requirements for Physicians	26
The Case Against Six-Month Limits on Buprenorphine Telehealth Prescribing	26
Revitalizing Primary Care Internal Medicine: Addressing the Hidden Curriculum	26
In basilar artery occlusion, tenecteplase within 24 h of symptom onset improved functional outcome vs. usual care at 90 d	25
In patients with type 2 diabetes and recent MI, colchicine reduced a composite CV outcome at 23 mo	25
Risk for Congenital Anomalies in Children Conceived With Medically Assisted Fertility Treatment	25
Stroke Rehabilitation: Synopsis of the 2024 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guidelines	24
In THA or TKA, risk for symptomatic VTE was higher with aspirin vs. enoxaparin at 90 d	24
Cognitively enhanced tai chi improved cognition vs. tai chi or stretching at 24 wk in older adults with MCI or memory concerns	24
Grief's Terrain	24
Standardization and Prediction to Control Confounding: Estimating Risk Differences and Ratios for Clinical Interpretations and Decision Making	24
Affirmative Action Bans and Enrollment of Students From Underrepresented Racial and Ethnic Groups in U.S. Public Medical Schools	24
In low-risk penicillin allergies, direct oral challenge was noninferior to skin testing followed by oral challenge	24
In latent autoimmune diabetes in adults, mortality was similar to T2DM but retinopathy was higher at 5.9 y	24
Ankle Osteoarthritis: Successful Completion of a Challenging Clinical Trial Comparing Surgical Treatments	24
In symptomatic AF with end-stage HF, adding catheter ablation to medical therapy improved clinical outcomes at 18 mo	24
Correction: Long COVID Definitions and Models of Care	23
In migraine with previous treatment failures, eptinezumab safely reduced migraine days at 1 to 12 wk	23
Self-reflection on an Elevated BMI	23
Enough Is Enough: On the Road to Eliminating “Sophie’s Choice” for U.S. Prescription Drugs	23
How Would You Manage HIV Pre-exposure Prophylaxis in This Patient With Medical Comorbidities?	23
Correction: Deep Learning to Estimate Cardiovascular Risk From Chest Radiographs	23
Anticoagulation for COVID-19: Seeking Clarity and Finding Yet More Gray	23
In adults with BMI ≥27 kg/m2 and type 2 diabetes, adding tirzepatide to a lifestyle intervention increased weight loss at 72 wk	23
In hospitalized patients with influenza, oseltamivir or peramivir may reduce hospital length of stay (low-certainty evidence)	23
In HF with mildly reduced or preserved ejection fraction, finerenone reduced worsening HF or CV death at 32 mo	23
After PCI and 1 mo of DAPT for ACS, ticagrelor alone vs. continued DAPT for 11 mo reduced bleeding without increasing MACCE	23
Doctor Dad	22
In acute ischemic stroke with a large core infarct, endovascular thrombectomy reduced disability at 90 d	22
Rugers, Remingtons, and Reality: A Gun Lover's Plea for a Safer Second Amendment	22
Putting Adult Vaccine Recommendations Into Action	22
Catholic Hospitals Should Improve Public Notification of Treatments They Conscientiously Refuse to Provide	22
Healing the Sick: A Timeline of Altruism	22
An Ordinary Day	22