OOIR: Observatory of International Research

Papers

(The median citation count of Annals of Clinical Biochemistry is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
The effectiveness of an automated algorithm as a tool for investigating the cause of anaemia in undiagnosed patients from general practitioners	131
Reducing neonatal phlebotomy blood losses through the accurate calculation of minimum test volume requirements	40
Falsely elevated type IV collagen caused in part by heterophilic antibodies: A case report	20
Determination and verification of reference intervals of serum immunoglobulin G at birth	19
A multicenter study comparing a point-of-care blood glucose metre with a blood gas analyser in infants by the Shikoku Neonatal Medical Research Group	16
Elevated Vitamin D leading to an Incidental Diagnosis of Multiple Myeloma	15
Prognostic significance of serum alkaline phosphatase for all-cause mortality in patients with hypertrophic cardiomyopathy: A cohort of the hospitalized population	12
The use of estimated Glomerular Filtration rate (GFR) in identifying pseudohyperkalaemia in primary care	11
Reference intervals of urinary kidney injury biomarkers for middle-aged men and women determined by quantitative protein mass spectrometry	11
Development and validation of interpretable machine learning models to predict glomerular filtration rate in chronic kidney disease Colombian patients	10
Familial hypercholesterolaemia with high triglycerides: A diagnostic challenge	8
Effect of albumin measurement methods on the albumin–bilirubin grade	8
Testing for lactase non-persistence in a Dutch population: Genotyping versus the hydrogen breath test	8
Acid freezes uricolysis in addition to glycolysis: Utility of fluoride-EDTA-citrate tube in the measurement of uric acid for patients administered rasburicase	8
Establishment of reference intervals for plasma metanephrines in seated position measured by LC-MS/MS and assessment of diagnostic performance in pheochromocytoma/paraganglioma	7
Usefulness of the 3-hydroxykynurenine/kynurenic acid ratio as a diagnostic biomarker for diffuse larger B-cell lymphoma	7
Elevated lactate dehydrogenase and reflexive myeloproliferative neoplasm molecular diagnostics	7
Detection of serum M-protein in acetonitrile precipitates by MALDI-TOF mass spectrometry: A novel, low-cost methodology	6
Effect of multiple loading FIT sample collection devices on faecal haemoglobin concentration	6
Rapid diagnostic strategies using high sensitivity troponin assays: what is the evidence and how should they be implemented?	6
Paired sensitivity analysis of four SARS-CoV-2 serological immunoassays in a longitudinal cohort of convalescent hospital staff	6
Practical approaches to the detection of macrotroponin	5
Validation of the Martin method to estimate low-density lipoprotein cholesterol concentrations in Japanese populations and a modified method for laboratory information system application	5
Adult and neonate TSH blood spot reference intervals	5
Evaluation of a laboratory reflex testing protocol to detect hypopituitarism in primary care presenting as hypothyroxinaemia	5

A SARS-CoV-2 minimum data standard to support national serology reporting	5
Machine learning predictive models of LDL-C in the population of eastern India and its comparison with directly measured and calculated LDL-C	5
Vitamin B12 reference intervals on Beckman, Roche and Siemens analytical platforms	4
UKMedLab2021 conference—building a new platform for the future	4
Coefficients of variation analyses of internal quality control status for blood lead in China from 2015 to 2023	4
Serum carbohydrate antigen 72-4 concentrations decrease with age in females but not in males in Beijing, China	4
Evaluation of the new Abbott®Alinity assay for the measurement of thyroglobulin antibodies in patients with differentiated thyroid carcinoma	4
Cross-sectional audit assessing the quality of dried bloodspot specimens received by UK metabolic biochemistry laboratories for the biochemical monitoring of individuals with Phenylketonuria	4
Thyroid reference ranges in pregnancy utilizing an Abbott Alinity platform in a multi-ethnic population in the UK	4
Measurement of uric acid in FC Mix tubes is not accurate	4
A rare case of persistent hyperkalaemia	4
Comparison of ultra-performance liquid chromatography and ARK immunoassay for therapeutic drug monitoring of voriconazole	4
Quantitative effects of bilirubin structural photoisomers on the measurement of direct bilirubin via the vanadate oxidation method	4
Faecal calprotectin is not necessarily required as a screen for significant bowel disease in primary care	4
Standardising lipid testing and reporting in the United Kingdom; a joint statement by HEART UK and The Association for Laboratory Medicine	4
Comparison of two primer-probe sets of Fusobacterium nucleatum using droplet digital polymerase chain reaction for the detection of colorectal neoplasia from faecal samples	4
Metronidazole is a chromatographic interference on a routine HPLC-UV assay for thiopurine metabolites	4
Comparison of faecal calprotectin using two collection and extraction strategies for the BÜHLMANN CALEX® Cap – possible implications for clinical cut-offs?	4
Biochip array technology for new psychoactive substances detection in biological samples: Evaluation of the specificity of the Randox Evidence Investigator^®	4
Corrigendum to “Improvement of point of care testing device for accurate whole blood glucose measurement in early neonates”	4
A United Kingdom-wide audit of the laboratory investigation of primary aldosteronism	3
A rapid liquid chromatography-tandem mass spectrometry method for the analysis of urinary 5-hydroxyindoleacetic acid (5-HIAA) that incorporates a ¹³C-labelled internal standard	3
Calculated small dense LDL-cholesterol and its correlation with the atherogenic index of plasma	3
Reference intervals for clinical biochemistry and haematology tests during normal pregnancy	3
Quality control of total carbon dioxide (CO₂) in serum or plasma using the Abbott Architect is affected by environmental pCO₂ concentrations	3
Low serum carnitine level is associated with increased urinary carnitine excretion in late pregnancy	3
The CELTIC ranges project (comprehensive and effective laboratory test reference intervals for Irish children) methodology and results for renal profile tests in plasma on the Roche modular^TM	3
Interference in immunoassay	3
Interferences in immunoassay: An estimate based on ‘real-world’ experience	3
Establishment of a novel ELISA system for measuring periostin independently of formation of the IgA complex	3
Importance of the preanalytical phase: Elevation of protein levels in cerebrospinal fluid samples due to inappropriate containers	3
The application and interpretation of laboratory biomarkers for the evaluation of vitamin B12 status	3
Maintaining glucose integrity ex-vivo: Impact of preanalytical specimen handling	3
Is there a role for C-reactive protein during and after labour?	3
Increased PD-1 expression of bone marrow T-cells in acute myeloid leukaemia patients after stem cell transplantation, and its association with overall survival	3
Glycated albumin and post-transplant diabetes mellitus in kidney transplant recipients	3
Identifying mislabelled samples: Machine learning models exceed human performance	3
Application of serum pools in insulin harmonization: Commutability and stability	3
High serum total vitamin B12 may mask biologically active B12 deficiency	3
Pregnancy-specific reference intervals: should we exclude women based on body mass index?	3
The preservation of synovial fluid using dimethyl sulfoxide	3
The effect of paraprotein polymerisation on quantitation by capillary zone electrophoresis and Hevylite®	3
How best to support point-of-care testing in the community?	3
Underreporting of synthetic cathinone poisoning with clinical immunoassays: An experimental and observational study	2
Do faecal test-based colorectal cancer screening pilots provide data that are reflected in subsequent programmes? Evidence from interval cancer proportions	2
Monoclonal protein polymerisation is the cause of IgM multiple isotype-matched monoclonal proteins	2
Example of use of clock time-dependent targets for patient-based quality control	2
Best practice in statistics: The use of log transformation	2
Improvement of point of care testing device for accurate whole blood glucose measurement in early neonates	2
Concordance in COVID-19 serology, bone mineralization, and inflammatory analytes between venous and self-collected capillary blood samples exposed to various pre-analytical conditions	2

Routine use of natriuretic peptides: Lessons from a big data analysis	2
Hepcidin analysis in pneumonia: Comparison of immunoassay and LC-MS/MS	2
Can patients with mild post-operative hyponatraemia following elective arthroplasty be discharged safely? A large-scale service evaluation suggests they can	2
Repeat measurements on patient samples identifies unpredictable and poorly reproducible cardiac troponin results with a high-sensitivity cardiac troponin assay	2
The preliminary study of delta checks for immunoglobulins and complements in the clinical laboratory	2
Impact of Hub & Spoke organization on the measurement of plasma ammonia	2
Verification of the Bühlmann fPELA turbo faecal elastase assay on the Binding Site Optilite benchtop analyser	2
Analytical characterization and clinical performance evaluation of a new point-of-care testing system for high-sensitivity cardiac troponin I assay	2
Development of blood collection tubes for glucose measurement using adenosine 3-phosphate and sodium fluoride as glycolytic inhibitors	2
Purple urine in Berdon syndrome: a rare finding in the clinic laboratory	2
Corrigendum to “Correlating arterial blood gas, acid-base and blood pressure abnormalities with outcomes in COVID-19 intensive care patients”	2
Metamizole (dipyrone) as an interferent in biochemical assays	2
Exclusion criteria for reference studies: Context is key	2
Detecting thyrotropin receptor mRNA from peripheral blood of patients with differentiated thyroid cancer rules out non-aggressive cases	2
Case report: Skin protective barrier cream interference in benzethonium chloride method for urine protein measurement in a 6-month-old girl	2
Elevated procalcitonin concentrations in severe Covid-19 may not reflect bacterial co-infection	2
Case report: Interference from isatuximab on serum protein electrophoresis prevented demonstration of complete remission in a myeloma patient	2
Air contamination of therapeutic drug monitoring assay reagents results in falsely high plasma ammonia levels	2
Validation of the Randox colorimetric assays for serum copper and zinc	2
Population-specific adjusted calcium equations	2
Climate change and clinical biochemistry	2
A survey of the reactivity of in vitro diagnostic bilirubin reagents developed in Japan using artificially prepared bilirubin materials: A comparison of synthetic delta, unconjugated, and tauri	2
EDTA plasma in glass and polyethylene terephthalate tubes is suitable for measurement of B-type natriuretic peptide on the Mindray CL-6000i	2
Establishment of trimester-specific reference intervals for thyroid stimulating hormone and free thyroxine during pregnancy in southwest China by indirect method	2
Establishment of sex-specific reference intervals for PIVKA-II in Southwest China: A real-world data analysis	2
Biochemical osteomalacia in adults undergoing vitamin D testing in the North-East of Scotland	2
Reducing the number of unnecessary laboratory tests within hospital through the use of educational interventions	1
Evaluation of the two-point calibration bromocresol green method, showing reduced deviation from the bromocresol purple method in sera from patients with hypoalbuminemia	1
Faecal haemoglobin concentration in adenoma, before and after polypectomy, approaches the ideal tumour marker	1
Establishment of reference intervals for estimated glomerular filtration rate in apparently healthy adults based on the full age spectrum equation: A single-centre study	1
Clinical performance of the Elecsys® anti-SARS-CoV-2 combined in an algorithm with two specific anti-IgG immunoassays for the evaluation of the serological response of patients with COVID-19 in a pop	1
Effect of automated feedback laboratory comments promoting good phlebotomy practice on the frequency of ethylenediaminetetraacetic acid (EDTA) contamination of serum samples	1
Serum cortisol assay performance following the 1 mg overnight dexamethasone suppression test	1
Establishment of risk quality control charts based on risk management strategies	1
Reference intervals for deconjugated urine metanephrines by Bhattacharya analysis	1
Establishment of CA19-9 reference intervals in an apparently healthy adult population in Singapore	1
A curious case of a negative control line on a dengue duo assay due to interference – A case report	1
EXPRESS: Uninterpretable cerebrospinal fluid absorbance scans caused by antibiotic therapy	1
Conflicting effects of haemolysis on plasma sodium and chloride are due to different haemolysis study protocols: A case for standardisation	1
Decrease in the internal quality control intermediate reproducibility imprecision of Cystatin C results in China in the years from 2014 to 2023	1
ACB Annual National Audit meeting – 24 September 2021	1
Time-resolved fluorescence immunoassay for urine retinol-binding protein is more sensitive than polyclonal and monoclonal assays	1
Authors’ reply to ‘Is there a role for C-reactive protein during and after labour?’	1
Low-level haemolysis negatively interferes with quantitation of vitamin E by the Chromsystems HPLC assay	1
Long term stability of lactate in uncentrifuged sodium fluoride/potassium oxalate blood collection tubes	1
Different serum sodium assay, different model for end stage liver disease - sodium scores in patients awaiting liver transplant: A cross-sectional study	1
Biomarkers in the diagnosis, prognosis and management of rheumatoid arthritis: A comprehensive review	1
A case of autoimmune hepatitis associated with the PCSK9 inhibitor alirocumab	1
Analytical assays and bootstrap resampling method to validate performance of the Roche Elecsys STAT highly sensitive troponin T assay and its application for the ‘rule-out’ part of ESC guidelines for	1
Closed analyser lids do not reduce the measurement uncertainty of serum total carbon dioxide	1
A further monoclonal antibody-based immunoturbidimetry option for measuring faecal elastase on the Optilite analyser	1
First case of very late-onset FHL2 in Spain with two variants in the PRF1 gene	1
Simultaneous quantification of serum symmetric dimethylarginine, asymmetric dimethylarginine and creatinine for use in a routine clinical laboratory	1
A UK national audit of the laboratory investigation of phaeochromocytoma and paraganglioma	1
Investigating the effect of icterus interference on a creatinine Roche enzymatic methodology	1
Acceptability of plasma ammonia results when samples are not transported and processed under ideal conditions	1
A rapid LC-MS/MS assay for the measurement of serum methotrexate in patients who have received high doses for chemotherapy	1
Pseudohyperphosphatemia induced by endogenous lipoproteins: New elements supporting an interference with ammonium phosphomolybdate-based methods	1
Distribution of biochemical and haematological parameters in an aging population from southern India: A cross-sectional analysis	1
MicroRNA in the diagnosis of lung cancer: An overview of ten systematic reviews	1
Reference values of parathyroid hormone in very low birth weight infants	1
Evaluation of cryoprotein investigation using a digital external quality assurance scheme	1
National recommendations to standardise acute kidney injury detection and alerting	1
Alternative diagnoses and demographics associated with a raised quantitative faecal immunochemical test in symptomatic patients	1
Efficacy and accuracy of faecal sampling by a digital rectal examination for faecal immunochemical testing	1
Tumour markers in prostate cancer: The post-prostate-specific antigen era	1
Molecular characterization of a novel homozygous deletion in β-globin cluster causing (δβ)⁰-Thalassemia among Tunisian family	1
LC-MS/MS the First 20 years: A Personal View	1
Updated adult ferritin reference intervals based on a large, healthy UK sample, measured on Roche Cobas series analysers	1