OOIR: Observatory of International Research

Papers

(The H4-Index of Biochemical Pharmacology is 51. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
ALKBH7 mediates the mitigative effect of bismuth drug against cisplatin-induced acute kidney injury	307
Editorial Board	264
Editorial Board	236
Hydroquinone destabilizes BIM mRNA through upregulation of p62 in chronic myeloid leukemia cells	176
Diabetes and the fabkin complex: A dual-edged sword	163
Identification of a dual JAK3/TEC family kinase inhibitor for atopic dermatitis therapy	151
Design, synthesis and anti-tumor activity of novel benzothiophenonaphthalimide derivatives targeting mitochondrial DNA (mtDNA) G-quadruplex	148
Luteolin binds Src, promotes STAT3 protein ubiquitination and exerts anti-melanoma effects in cell and mouse models	133
PGC‐1α activation ameliorates cancer-induced bone pain via inhibiting apoptosis of GABAergic interneurons	127
Alisol A 24-Acetate combats Methicillin-Resistant Staphylococcus aureus infection by targeting the mevalonate biosynthesis	122
Unveiling ODP4: A breakthrough in PCOS treatment via BAT transplantation	122
Butyrolactone I from Aspergillus fungi blocks neutrophil FPR1 to alleviate acute respiratory distress syndrome	108
Metformin exhibits inhibitory effects on ferroptosis and alleviates chondrocyte metabolic imbalance in osteoarthritis models, as well as Erastin-induced ferroptosis, through the modulation of the P53/	102
Ammonium tetrathiomolybdate attenuates acetaminophen-induced acute liver failure by inhibiting the TRPV4/Calcium/NF-κB signaling pathway	99
Exploring tryptophan metabolism: The transition from disturbed balance to diagnostic and therapeutic potential in metabolic diseases	96
PLK-3-mediated phosphorylation of BAP1 prevents diabetic retinopathy	95
A novel L-shaped ortho-quinone analog as PLK1 inhibitor blocks prostate cancer cells in G2 phase	94
Growth factor receptor-bound protein 2-mediated corneal epithelial injury drives depression-associated dry eye disease	93
Corrigendum to “Dose-dependent regulation of mitochondrial function and cell death pathway by sorafenib in liver cancer cells” [Biochem. Pharmacol. 176 (2020) 113902]	88
Corrigendum to “Targeting AhR suppresses hepatocyte ferroptosis in MASH by regulating the Pten/Akt/β catenin axis” [Biochem. Pharmacol. 232 (2025) 116711]	83
PXR as the tipping point between innate immune response, microbial infections, and drug metabolism	82
Decreased HMGB1 expression contributed to cutaneous toxicity caused by lapatinib	80
Influence of tumor microenvironment on the different breast cancer subtypes and applied therapies	77
Inhibition of circular RNA ASPH reduces the proliferation and promotes the apoptosis of hepatic stellate cells in hepatic fibrosis	71
CD73 mitigates hepatic damage in alcoholic steatohepatitis by regulating PI3K/AKT-mediated hepatocyte pyroptosis	70

Ultraviolet-treated riboflavin alleviates atopic dermatitis by inhibiting NLRP3 inflammasome activation and M1 macrophage polarization via histone lactylation	68
Recent trends in fragment-based anticancer drug design strategies against different targets: A mini-review	67
Renoprotective effect of Nesfatin-1 in Adenine-Induced Chronic kidney Disease: An in vitro and in vivo study	66
CircDUSP16 mediates the effect of triple-negative breast cancer in pirarubicin via the miR-1224-3p/TFDP2 axis	64
IP3R-dependent Ca2+ signaling in the endoplasmic reticulum is required for deoxynivalenol-induced intestinal stem cell injury	62
ALDH1A1 confers resistance to RAF/MEK inhibitors in melanoma cells by maintaining stemness phenotype and activating PI3K/AKT signaling	62
Indole selectively suppresses aldosterone overproduction via binding to the catalytic site of CYP11B2	61
Evidence for the contribution of vasopressin V1B receptors in the pathophysiology of depression	61
Peptide GLP-1 receptor agonists: From injection to oral delivery strategies	60
RNA-binding protein GIGYF2 promotes colorectal cancer progression through activation of the METTL3/SERP1/STAT3 axis in an m6A-IGF2BP2-dependent manner	60
Melatonin protects vascular homeostasis by restoring PVAT redox balance in arterial hypertension	59
LINC00324 promotes cell proliferation and metastasis of esophageal squamous cell carcinoma through sponging miR-493-5p via MAPK signaling pathway	59
ALA-PDT augments intense inflammation in the treatment of acne vulgaris by COX2/TREM1 mediated M1 macrophage polarization	58
Interplay between the renin angiotensin system and oxidative stress contributes to alcohol addiction by stimulating dopamine accumulation in the mesolimbic pathway	58
The potent role of Src kinase-regulating glucose metabolism in cancer	58
Neuroanatomical distribution of fluorophores within adult RXFP3 Cre-tdTomato/YFP mouse brain	57
Restoring mitochondria–endoplasmic reticulum–synapse axis: a proteomic dissection of Rhein’s multi-pathway antidepressant mechanism	57
Emerging role of m6A modification in fibrotic diseases and its potential therapeutic effect	55
Methionine cycle in nonalcoholic fatty liver disease and its potential applications	55
Modulation of contextual fear acquisition and extinction by acute and chronic relaxin-3 receptor (RXFP3) activation in the rat retrosplenial cortex	55
Bile acids and bile acid activated receptors in the treatment of Covid-19	54
Cellular crosstalk in doxorubicin-induced cardiotoxicity: underlying mechanisms and therapeutic strategies	53
EP3 promotes macrophage M1-polarization to play a critical role in diabetic renal injury	52
Bromodomain containing protein 4 (BRD4) and cancer therapy: A glimpse at dual-target drug development	52
Exploring the mechanism of nonylphenol-induced myocardial fibrosis based on TGF-β1/Smads signaling pathway	52
SEMA7A orchestrates the colorectal cancer tumor microenvironment via PlexinC1: coordinating angiogenesis and macrophage M2 polarization	51
HDAC6 is involved in diabetic nephropathy by regulating TGFβ/Smads and NF-κB signaling pathways	51