Biochemical Pharmacology

Article	Citations
ALKBH7 mediates the mitigative effect of bismuth drug against cisplatin-induced acute kidney injury	235
AMPK-activation by catecholamines induces autophagy and cell proliferation in cardiac fibroblasts	186
HDAC6 is involved in diabetic nephropathy by regulating TGFβ/Smads and NF-κB signaling pathways	162
Editorial Board	159
Corrigendum to “Targeting AhR suppresses hepatocyte ferroptosis in MASH by regulating the Pten/Akt/β catenin axis” [Biochem. Pharmacol. 232 (2025) 116711]	147
PGC‐1α activation ameliorates cancer-induced bone pain via inhibiting apoptosis of GABAergic interneurons	137
Editorial Board	134
CircDUSP16 mediates the effect of triple-negative breast cancer in pirarubicin via the miR-1224-3p/TFDP2 axis	128
CD73 mitigates hepatic damage in alcoholic steatohepatitis by regulating PI3K/AKT-mediated hepatocyte pyroptosis	119
Inhibition of circular RNA ASPH reduces the proliferation and promotes the apoptosis of hepatic stellate cells in hepatic fibrosis	119
MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway	108
The relationship between tumor metabolism and 5-fluorouracil resistance	107
Ultraviolet-treated riboflavin alleviates atopic dermatitis by inhibiting NLRP3 inflammasome activation and M1 macrophage polarization via histone lactylation	102
Histone deacetylase 6 modulates autophagy through HIF-1α/BNIP3 signaling in lung cancer	102
CDP-choline modulates cholinergic signaling and gut microbiota to alleviate DSS-induced inflammatory bowel disease	98
Bile acids and bile acid activated receptors in the treatment of Covid-19	89
Identification of a dual JAK3/TEC family kinase inhibitor for atopic dermatitis therapy	86
Unveiling ODP4: A breakthrough in PCOS treatment via BAT transplantation	79
Anti-inflammatory, but not osteoprotective, effect of the TRAF6/CD40 inhibitor 6877002 in rodent models of local and systemic osteolysis	76
A novel L-shaped ortho-quinone analog as PLK1 inhibitor blocks prostate cancer cells in G2 phase	76
Hydroquinone destabilizes BIM mRNA through upregulation of p62 in chronic myeloid leukemia cells	75
Corrigendum to “Dose-dependent regulation of mitochondrial function and cell death pathway by sorafenib in liver cancer cells” [Biochem. Pharmacol. 176 (2020) 113902]	73
Excess glucocorticoid exposure contributes to adipose tissue fibrosis which involves macrophage interaction with adipose precursor cells	73
Diabetes and the fabkin complex: A dual-edged sword	72
Drug-oxidizing and conjugating non-cytochrome P450 (non-P450) enzymes in cynomolgus monkeys and common marmosets as preclinical models for humans	71

Alisol A 24-Acetate combats Methicillin-Resistant Staphylococcus aureus infection by targeting the mevalonate biosynthesis	71
Exploring tryptophan metabolism: The transition from disturbed balance to diagnostic and therapeutic potential in metabolic diseases	71
PLK-3-mediated phosphorylation of BAP1 prevents diabetic retinopathy	70
Neuroanatomical distribution of fluorophores within adult RXFP3 Cre-tdTomato/YFP mouse brain	68
Modulation of contextual fear acquisition and extinction by acute and chronic relaxin-3 receptor (RXFP3) activation in the rat retrosplenial cortex	66
Evidence for the contribution of vasopressin V1B receptors in the pathophysiology of depression	65
Ammonium tetrathiomolybdate attenuates acetaminophen-induced acute liver failure by inhibiting the TRPV4/Calcium/NF-κB signaling pathway	64
PXR as the tipping point between innate immune response, microbial infections, and drug metabolism	63
Luteolin binds Src, promotes STAT3 protein ubiquitination and exerts anti-melanoma effects in cell and mouse models	60
Influence of tumor microenvironment on the different breast cancer subtypes and applied therapies	59
Renoprotective effect of Nesfatin-1 in Adenine-Induced Chronic kidney Disease: An in vitro and in vivo study	59
Decreased HMGB1 expression contributed to cutaneous toxicity caused by lapatinib	57
Cytochrome P450 2E1 gene knockout or inhibition prevents obesity induced by high-fat diet via regulating energy expenditure	55
An organogold compound impairs Leishmania amazonensis amastigotes survival and delays lesion progression in murine cutaneous leishmaniasis: Mechanistic insights	55
Metformin exhibits inhibitory effects on ferroptosis and alleviates chondrocyte metabolic imbalance in osteoarthritis models, as well as Erastin-induced ferroptosis, through the modulation of the P53/	55
LINC00324 promotes cell proliferation and metastasis of esophageal squamous cell carcinoma through sponging miR-493-5p via MAPK signaling pathway	55
Investigation of the role and mechanism of dapagliflozin in mitigating renal injury in rats afflicted with diabetic kidney disease	53
Design, synthesis and anti-tumor activity of novel benzothiophenonaphthalimide derivatives targeting mitochondrial DNA (mtDNA) G-quadruplex	53
ALDH1A1 confers resistance to RAF/MEK inhibitors in melanoma cells by maintaining stemness phenotype and activating PI3K/AKT signaling	52
Effects of heme oxygenase 1 in the molecular changes and neuropathy associated with type 2 diabetes in mice	52
ALA-PDT augments intense inflammation in the treatment of acne vulgaris by COX2/TREM1 mediated M1 macrophage polarization	51
Recent trends in fragment-based anticancer drug design strategies against different targets: A mini-review	49
Peptide GLP-1 receptor agonists: From injection to oral delivery strategies	48
A variety of cytochrome P450 enzymes and flavin-containing monooxygenases in dogs and pigs commonly used as preclinical animal models	48
Interplay between the renin angiotensin system and oxidative stress contributes to alcohol addiction by stimulating dopamine accumulation in the mesolimbic pathway	48
Pharmacological inhibition of HDAC6 suppresses NLRP3 inflammasome-mediated IL-1β release	47
Methionine cycle in nonalcoholic fatty liver disease and its potential applications	46
Emerging role of m6A modification in fibrotic diseases and its potential therapeutic effect	46
The potent role of Src kinase-regulating glucose metabolism in cancer	45
Translational potential of targeting Anoctamin-1-Encoded Calcium-Activated chloride channels in hypertension	45
Editorial Board	44
KDM6B knockdown alleviates sleep deprivation-induced cerebrovascular lesions in APP/PS1 mice by inhibiting PARP16 expression	44
Carbon monoxide in cell signaling and potential therapeutics	44
Macrophage scavenger receptor A1 antagonizes abdominal aortic aneurysm via upregulating IRG1	43
PPARα/δ dual agonist H11 alleviates diabetic kidney injury by improving the metabolic disorders of tubular epithelial cells	43
Identifying inhibitors of Trypanosoma cruzi nucleoside diphosphate kinase 1 as potential repurposed drugs for Chagas’ disease	43
Serum-derived extracellular vesicles mediate acquired multidrug resistance of MCF-7 breast cancer cells induced by chemotherapeutic drugs	43
Reynoutrin targets EphB4 to ameliorate hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus	43
Itaconate alleviates β2-microglobulin-induced cognitive impairment by enhancing the hippocampal amino-β-carboxymuconate-semialdehyde-decarboxylase/picolinic acid pathway	43
The dual targeting effects of KD025 on casein kinase 2 and ROCK2 in a mouse model of diet-induced obesity	43
Knockdown of Galectin-9 alleviates rheumatoid arthritis through suppressing TNF-α-induced activation of fibroblast-like synoviocytes	42
Methyl-oxazolomycin A: A novel oxazolomycin analog with potent selective estrogen receptor degrading activity in breast cancer cells	42
DEC1 deficiency promotes osteoclastic activity by augmenting NFATc1 signaling via transactivation and the Ca2+/calcineurin pathway	40
Targeting non-coding RNAs and N6-methyladenosine modification in hepatocellular carcinoma	40
Mast cell activation induced by tamoxifen citrate via MRGPRX2 plays a potential adverse role in breast cancer treatment	40
GRHL3 drives radiotherapy resistance and blocks the anti-tumor response of NK and CD4+ T cells in lung squamous cell carcinoma via RNF2	40
Torachrysone-8-O-β-d-glucoside mediates anti-inflammatory effects by blocking aldose reductase-catalyzed metabolism of lipid peroxidation products	39
Combining Sorafenib, Se-methylselenocysteine, and α-Ketoacid for synergistic cytotoxicity in Hepatocellular carcinoma cell lines	39
Potential small effector molecules restoring cellular defects due to sialic acid biosynthetic enzyme deficiency: Pathological relevance to GNE myopathy	39
Venom composition and bioactive RF-amide peptide toxins of the saddleback caterpillar, Acharia stimulea (Lepidoptera: Limacodidae)	38

Melatonin alleviates brain injury in copper-laden rats: Underlying benefits for Wilson’s disease	38
Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo	38
Astragaloside IV as a potent vWbp inhibitor: An innovative strategy to mitigate foodborne Staphylococcus aureus infections	38
Oleoylethanolamide alleviates hyperlipidaemia-mediated vascular calcification via attenuating mitochondrial DNA stress triggered autophagy-dependent ferroptosis by activating PPARα	37
SMURF1 leads to the β-catenin signaling-mediated progression of esophageal squamous carcinoma by losing PATZ1-induced CCNG2 transcription	37
The value of neck adipose tissue as a predictor for metabolic risk in health and type 2 diabetes	37
GPR55: Physiological functions and therapeutic potential in depression	37
Dexmedetomidine alleviates anxiety-like behavior in mice following peripheral nerve injury by reducing the hyperactivity of glutamatergic neurons in the anterior cingulate cortex	37
Targeting fuel pocket of cancer cell metabolism: A focus on glutaminolysis	37
Rosavidin protects against PM2.5-induced lung toxicity via inhibition of NLRP3 inflammasome-mediated pyroptosis by activating the PI3K/AKT pathway	37
6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model	36
Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines	36
Treatment with S-adenosylmethionine ameliorates irinotecan-induced intestinal barrier dysfunction and intestinal microbial disorder in mice	35
Recent advances in studies on FtsZ inhibitors	35
LILRB4 as a novel immunotherapeutic target for multiple diseases	35
Immunometabolic attributes and mitochondria-associated signaling of Tumor-Associated Macrophages in tumor microenvironment modulate cancer progression	35
SIS3 suppresses osteoclastogenesis and ameliorates bone loss in ovariectomized mice by modulating Nox4-dependent reactive oxygen species	34
Peroxisome proliferator-activated receptor (PPAR) agonists as a potential therapy for inherited metabolic disorders	34
Ursolic acid augments the chemosensitivity of drug-resistant breast cancer cells to doxorubicin by AMPK-mediated mitochondrial dysfunction	34
Human flavin-containing monooxygenase 1 and its long-sought hydroperoxyflavin intermediate	34
Isoflavone glucoside genistin, an inhibitor targeting Sortase A and Listeriolysin O, attenuates the virulence of Listeria monocytogenes in vivo and in vitro	34
Tumor Cells-derived exosomal CircRNAs: Novel cancer drivers, molecular mechanisms, and clinical opportunities	33
FGF2 drives osteosarcoma metastasis through activating FGFR1-4 receptor pathway-mediated ICAM-1 expression	33
Exploring the glycation association with dyslipidaemia: Novel approach for diabetic nephropathy	33
The short-chain fatty acid acetate modulates orexin/hypocretin neurons: A novel mechanism in gut-brain axis regulation of energy homeostasis and feeding	33
Effect of pharmacological heart failure drugs and gene therapy on Danon's cardiomyopathy	32
Uremic toxins activate CREB/ATF1 in endothelial cells related to chronic kidney disease	32
Dual-specificity tyrosine phosphorylation-regulated kinase 1A promotes the inclusion of amyloid precursor protein exon 7	32
Circadian oscillator NPAS2 regulates diurnal expression and activity of CYP1A2 in mouse liver	32
Physiological and pharmacological overview of the gonadotropin releasing hormone	32
Immunomodulatory effects of antiangiogenic tyrosine kinase inhibitors in renal cell carcinoma models: Impact on following anti-PD-1 treatments	31
ALOX5 promotes autophagy-dependent ferroptosis by activating the AMPK/mTOR pathway in melanoma	31
Viral Vectors, Exosomes, and Vexosomes: Potential armamentarium for delivering CRISPR/Cas to cancer cells	31
Inhibition of γ-secretase/Notch pathway as a potential therapy for reversing cancer drug resistance	31
Epigallocatechin gallate relieves asthmatic symptoms in mice by suppressing HIF-1α/VEGFA-mediated M2 skewing of macrophages	31
Understanding resistance acquisition by Pseudomonas aeruginosa and possible pharmacological approaches in palliating its pathogenesis	30
Mitomycin induced the senescence of alveolar epithelial cells by targeting peroxiredoxin I	30
Leptin impairs the therapeutic efficacy of adipose-derived mesenchymal stem cells by inducing apoptosis through NLRP3 inflammasomes activation	30
Chrysophanol prevents IL-1β-Induced inflammation and ECM degradation in osteoarthritis via the Sirt6/NF-κB and Nrf2/NF-κB axis	30
Acyclovir resistance in herpes simplex viruses: Prevalence and therapeutic alternatives	30
Targeting fibroblast activation protein with chimeric antigen receptor macrophages	30
Sirtuin1-p53: A potential axis for cancer therapy	30
Role of sirtuins in hepatocellular carcinoma progression and multidrug resistance: Mechanistical and pharmacological perspectives	30
Ifosfamide alleviates autoimmune toxicity and enhances antitumor efficacy in melanoma immunotherapy	30
Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders	30
P4HA3 depletion induces ferroptosis and inhibits colorectal cancer growth by stabilizing ACSL4 mRNA	29
SIRT6 regulates endothelium-dependent relaxation by modulating nitric oxide synthase 3 (NOS3)	29
Editorial Board	29
Emerging roles of senolytics/senomorphics in HIV-related co-morbidities	29
xCT/Slc7a11 promotes pulmonary arterial hypertension by disrupting AMPKα suppression of mTOR activation	29
A review on the effect of COX-2-mediated mechanisms on development and progression of gastric cancer induced by nicotine	29
Maladaptive regeneration and metabolic dysfunction associated steatotic liver disease: Common mechanisms and potential therapeutic targets	29
Therapeutic of a white adipose tissue-specific bivalent aptamer in obesity	29
Corrigendum to “Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury“ [Biochem. Pharmacol. 63(1) (2002)	29
Corrigendum to “DOCK2 contributes to endotoxemia-induced acute lung injury in mice by activating proinflammatory macrophages” [Biochem. Pharmacol. 184 (2021) 114399]	29
Differential contribution of renal cytochrome P450 enzymes to kidney endothelial dysfunction and vascular oxidative stress in obesity	28
Ponatinib exacerbate renal injury in systemic lupus erythematosus mouse model through PDGFR-PI3K/AKT pathway	28
Corrigendum to “Geraniol ameliorates acute liver failure induced by lipopolysaccharide/D-galactosamine via regulating macrophage polarization and NLRP3 inflammasome activation by PPAR-γ methylation Ge	28
Mefunidone ameliorates acute liver failure in mice by inhibiting MKK4-JNK pathway	28
Detailed resume of S-methyltransferases: Categories, structures, biological functions and research advancements in related pathophysiology and pharmacotherapy	28
Mitochondrial elongation confers protection against doxorubicin-induced cardiotoxicity	28
Finding new analgesics: Computational pharmacology faces drug discovery challenges	28
Structure and function of the highly homologous deubiquitinases ubiquitin specific peptidase 25 and 28: Insights into their pathophysiological and therapeutic roles	28
IOX-1 suppresses metastasis of osteosarcoma by upregulating histone H3 lysine trimethylation	28
Cytarabine-induced destabilization of MCL1 mRNA and protein triggers apoptosis in leukemia cells	28
TNFα blockade reverses vascular and uteroplacental matrix metalloproteinases imbalance and collagen accumulation in hypertensive pregnant rats	28
Macrophage-derived human resistin promotes perivascular adipose tissue dysfunction in experimental inflammatory arthritis	28
Engineering a long acting, non-biased relaxin agonist using Protein-in-Protein technology	28
m6A modification impacts hepatic drug and lipid metabolism properties by regulating carboxylesterase 2	27
Novel DCPIB analogs as dual inhibitors of VRAC/TREK1 channels reduced cGAS-STING mediated interferon responses	27
Possibility of averting cytokine storm in SARS-COV 2 patients using specialized pro-resolving lipid mediators	27
PCSK9 regulates myofibroblast transformation through the JAK2/STAT3 pathway to regulate fibrosis after myocardial infarction	27
Antibody-drug conjugates for non-small cell lung cancer: Advantages and challenges in clinical translation	27
CEMIP promotes small cell lung cancer proliferation by activation of glutamine metabolism via FBXW7/c-Myc-dependent axis	27
Positive programming of the GC-IGF1 axis mediates adult osteoporosis susceptibility in male offspring rats induced by prenatal dexamethasone exposure	27
A rational foundation for micheliolide-based combination strategy by targeting redox and metabolic circuit in cancer cells	27
Mithramycin suppresses tumor growth by regulating CD47 and PD-L1 expression	27
The critical roles of STING in mitochondrial homeostasis	27
Role of sodium taurocholate cotransporting polypeptide (NTCP) in HBV-induced hepatitis: Opportunities for developing novel therapeutics	26
Overview of the therapeutic strategies for ER positive breast cancer	26

Chronic kidney disease-induced muscle atrophy: Molecular mechanisms and promising therapies	26
BMAL1 plays a crucial role in immune homeostasis during sepsis-induced acute lung injury	26
MiR-466b-3p/HDAC7 meditates transgenerational inheritance of testicular testosterone synthesis inhibition induced by prenatal dexamethasone exposure	26
Targeting regulated chondrocyte death in osteoarthritis therapy	26
Editorial Board	26
Preclinical evaluation of new drug-drug interactions of lomitapide: A proposal for novel mechanism of interaction associated with lipid metabolic changes	26
Non-covalent mTOR inhibition suppresses NLRP3-GSDMD inflammasome-mediated pyroptosis	26
Protein prenylation in islet β-cell function in health and metabolic stress	26
Citrulline activates adenosine receptors: New insight into metabolic pathways interaction	26
Polo-like kinase 1 (PLK1) is a novel CARD14-binding protein in keratinocytes	25
miR-486-5p-rich extracellular vesicles derived from patients with olanzapine-induced insulin resistance negatively affect glucose-regulating function	25
Corrigendum to “TTI-101: A competitive inhibitor of STAT3 that spares oxidative phosphorylation and reverses mechanical allodynia in mouse models of neuropathic pain” [Biochem. Pharmacol. 192 (2021) 1	25
Eicosatrienoic acid inhibits estradiol synthesis through the CD36/FOXO1/CYP19A1 signaling pathway to improve PCOS in mice	25
Iron supplementation protects against renal ischemia–reperfusion injury by enhancing mitochondrial respiratory complex assembly	25
Enhanced thermogenesis in PAS Kinase-deficient male mice	25
Quassinoid analogs exert potent antitumor activity via reversible protein biosynthesis inhibition in human colorectal cancer	25
Editorial Board	25
The V-ATPase a3 subunit deficiency affects osteoarthritis via mTOR-Mediated autophagy levels in subchondral bone	25
Design and characterization of a triazole-based growth hormone secretagogue receptor modulator inhibiting the glucoregulatory and feeding actions of ghrelin	25
Extracellular nucleotides in smooth muscle contraction	24
Editorial Board	24
Cardiac human bitter taste receptors contain naturally occurring variants that alter function	24
A systematic review and meta-analysis of environmental contaminant exposure impacts on weight loss and glucose regulation during calorie-restricted diets in preclinical studies: Persistent organic pol	24
Therapeutic targeting of Wnt antagonists by small molecules for treatment of osteoporosis	24
Animal models of acute lymphoblastic leukemia: Recapitulating the human disease to evaluate drug efficacy and discover therapeutic targets	24
Inhibition of soluble epoxide hydrolase relieves adipose inflammation via modulating M1/M2 macrophage polarization to alleviate airway inflammation and hyperresponsiveness in obese asthma	24
Redox regulation by carotenoids: Evidence and conflicts for their application in cancer	24
Oridonin combined with cisplatin synergistically induces apoptosis by activating the NOXA-BCL2 axis in esophageal squamous cell carcinoma	24
Selpercatinib attenuates bleomycin-induced pulmonary fibrosis by inhibiting the TGF-β1 signaling pathway	24
Azithromycin modulates Teff/Treg balance in retinal inflammation via the mTOR signaling pathway	24
Corrigendum to “Cardioprotective effects of melatonin and metformin against doxorubicin-induced cardiotoxicity in rats are through preserving mitochondrial function and dynamics” [Biochem. Pharmacol.	24
Activated microglia secretome and proinflammatory cytokines increase neuronal mu-opioid receptor signalling and expression	24
FXR agonists for colorectal and liver cancers, as a stand-alone or in combination therapy	24
Biology and pharmacology of platelet-type 12-lipoxygenase in platelets, cancer cells, and their crosstalk	23
Anti-inflammatory mechanism of the MLKL inhibitor necrosulfonamide in LPS- or poly(I:C)-induced neuroinflammation and necroptosis	23
Implication of Let7b/AhR/ARNT/HMGB1/RAGE cascade in neuroplasticity disturbances induced by glucocorticoids and the promising reversible effect of 3,3 diindolymethane: Bidirectional crosstalk of Aryl	23
Mst1 inhibition mitigates steroid-induced femoral head osteonecrosis by modulating autophagy in bone microvascular endothelial cells	23
Triflupromazine and tranylcypromine alleviate primary cisplatin resistance in lung adenocarcinoma by promoting LDHA-mediated AMBRA1 ubiquitination	23
An A-ring substituted evodiamine derivative with potent anticancer activity against human non-small cell lung cancer cells by targeting heat shock protein 70	23
Ubiquitin ligase TRIM63 regulates HOXA10 expression to mediate fatty acid β-oxidation and suppress lung adenocarcinoma metastasis	23
Novel pharmacological inhibition of JMJD3 improves necrotizing enterocolitis by attenuating the inflammatory response and ameliorating intestinal injury	23
PPARγ activation by fisetin mitigates vascular smooth muscle cell senescence via the mTORC2-FoxO3a-autophagy signaling pathway	23
Discovery of novel carboxylesterase 2 inhibitors for the treatment of delayed diarrhea and ulcerative colitis	23
Mechanotransduction and the extracellular matrix: Key drivers of lung pathologies and drug responsiveness	23
Targeted delivery of a colchicine analogue provides synergy with ATR inhibition in cancer cells	23
Canonical DDR activation by EMT inducing agent 5-Fluorouracil is modulated by a cannabinoid based combinatorial approach via inducing autophagy and suppression of vimentin expression	23
The role of taurine through endoplasmic reticulum in physiology and pathology	23
Enterogastric and enterohepatic recycling of dendrobine in rats: a novel disposition mechanism responsible for pharmacokinetic multiple peaks	23
Resolvin D3 improves the impairment of insulin signaling in skeletal muscle and nonalcoholic fatty liver disease through AMPK/autophagy-associated attenuation of ER stress	22
Curing childhood cancer the “Natural” Way: Nature as the source of chemotherapy agents	22
AdipoRon and ADP355, adiponectin receptor agonists, in Metabolic-associated Fatty Liver Disease (MAFLD) and Nonalcoholic Steatohepatitis (NASH): A systematic review	22
Metallodrugs: Synthesis, mechanism of action and nanoencapsulation for targeted chemotherapy	22
Selective activation of cannabinoid receptors by cannabis terpenes	22
Metabolic activation of drugs by cytochrome P450 enzymes: Biochemical insights into mechanism-based inactivation by fibroblast growth factor receptor inhibitors and chemical approaches to attenuate re	22
Structure-based optimization of Toddacoumalone as highly potent and selective PDE4 inhibitors with anti-inflammatory effects	22
Calcium saccharate/DUSP6 suppresses renal cell carcinoma glycolytic metabolism and boosts sunitinib efficacy via the ERK-AKT pathway	22
Omega-3 polyunsaturated fatty acids alleviate hyperuricemic nephropathy by inhibiting renal pyroptosis through GPR120	22
A novel GSH depletor for simultaneous ferroptosis and cuproptosis Activation in hepatocellular carcinoma	22
Role of long non-coding RNAs in adipose tissue metabolism and associated pathologies	22
Delineating the tumour-regulatory roles of EYA4	22
The increasing role of pigment epithelium-derived factor in metastasis: from biological importance to a promising target	22
Integrated metabolomics and transcriptomics reveal the neuroprotective effect of nervonic acid on LPS-induced AD model mice	22
Glucocorticoids and natural killer cells: A suppressive relationship	22
Editorial Board	21
Luxeptinib disables NLRP3 inflammasome-mediated IL-1β release and pathways required for secretion of inflammatory cytokines IL-6 and TNFα	21
Isoliensinine suppresses bone loss by targeted inhibition of RANKL-RANK binding	21
Sterol regulation of developmental and oncogenic Hedgehog signaling	21
Cancer stem cells: Recent insights and therapies	21
The blockade of neddylation alleviates ventilator-induced lung injury by reducing stretch-induced damage to pulmonary epithelial cells	21
YTHDC1 maintains trophoblasts function by promoting degradation of m6A-modified circMPP1	21
AMPK activation attenuates HER3 upregulation and Neuregulin-Mediated rescue of cell proliferation in HER2-Overexpressing breast cancer cell lines exposed to lapatinib	21
Curcumin protects against the age-related hearing loss by attenuating apoptosis and senescence via activating Nrf2 signaling in cochlear hair cells	21
TFAP2A is involved in neuropathic pain by regulating Grin1 expression in glial cells of the dorsal root ganglion	21
Potential role of modulating autophagy levels in sensorineural hearing loss	21
Vesicular monoamine transporter-2 inhibitor JPC-141 prevents methamphetamine-induced dopamine toxicity and blocks methamphetamine self-administration in rats	21
3-Hydroxybutyrate ameliorates sepsis-associated acute lung injury by promoting autophagy through the activation of GPR109α in macrophages	21
Histone lactylation-driven YTHDF2 promotes non-small cell lung cancer cell glycolysis and stemness by recognizing m6A modification of SFRP2	21
Corrigendum to “Obesity II: Establishing causal links between chemical exposures and obesity” [Biochem. Pharmacol. 199 (2022) 115015]	21
Antiplatelet drug ticagrelor suppresses triple negative breast cancer metastasis by targeting PI3K	21
Relaxin as a treatment for musculoskeletal fibrosis: What we know and future directions	21
Butyrate promotes kidney resilience through a coordinated kidney protective response in tubular cells	21
ASCT2-mediated glutamine uptake promotes Th1 differentiation via ROS-EGR1-PAC1 pathway in oral lichen planus	21
Flavokawain B is an effective natural peroxisome proliferator-activated receptor γ-selective agonist with a strong glucose-lowering effect	21
Pathogenic mitochondrial dysfunction and metabolic abnormalities	21
Detailed functional characterization of four nanobodies as positive allosteric modulators of the human calcium-sensing receptor	21
AT1 receptors modulate ethanol-induced loss of anticontractile effect of perivascular adipose tissue	21
Molecular Dissection of the AHR-AREG driven EGFR-ERK1/2-CyclinD1 axis in acquired lenvatinib resistance of Hepatocellular carcinoma	21
Corrigendum to “Apoptotic effects of mahanine on human leukemic cells are mediated through crosstalk between Apo-1/Fas signaling and the Bid protein and via mitochondrial pathways” [Biochem. Pharmacol	20
Corrigendum to “Resveratrol inhibits epithelial-mesenchymal transition and renal fibrosis by antagonizing the hedgehog signaling pathway” [Biochem. Pharmacol. 92 (2014) 484–493]	20
Selective stabilization of the intermediate inactivated Na+ channel by the new-generation anticonvulsant rufinamide	20
Vitamin B12 reversed anxiety and depression induced by adolescent nicotine withdrawal through alteration the inflammatory, oxidative and serotoninergic profiles in male rats	20
Inhibition of proteasome, but not lysosome, upregulates organic anion transporter 3 in vitro and in vivo	20
Licoisoflavone A inhibits colorectal cancer cell proliferation through targeting CDK2-Cyclin E1 axis-mediated cell cycle transition	20
Acknowledgment	20
Differential regulation of histamine H1 receptor-mediated ERK phosphorylation by Gq proteins and arrestins	20