Biochemical Pharmacology

Article	Citations
PGC‐1α activation ameliorates cancer-induced bone pain via inhibiting apoptosis of GABAergic interneurons	225
Influence of tumor microenvironment on the different breast cancer subtypes and applied therapies	173
Editorial Board	170
Inhibition of circular RNA ASPH reduces the proliferation and promotes the apoptosis of hepatic stellate cells in hepatic fibrosis	160
CircDUSP16 mediates the effect of triple-negative breast cancer in pirarubicin via the miR-1224-3p/TFDP2 axis	151
Decreased HMGB1 expression contributed to cutaneous toxicity caused by lapatinib	144
Interplay between the renin angiotensin system and oxidative stress contributes to alcohol addiction by stimulating dopamine accumulation in the mesolimbic pathway	133
Design, synthesis and anti-tumor activity of novel benzothiophenonaphthalimide derivatives targeting mitochondrial DNA (mtDNA) G-quadruplex	129
A variety of cytochrome P450 enzymes and flavin-containing monooxygenases in dogs and pigs commonly used as preclinical animal models	124
CDP-choline modulates cholinergic signaling and gut microbiota to alleviate DSS-induced inflammatory bowel disease	115
CD73 mitigates hepatic damage in alcoholic steatohepatitis by regulating PI3K/AKT-mediated hepatocyte pyroptosis	113
Metformin exhibits inhibitory effects on ferroptosis and alleviates chondrocyte metabolic imbalance in osteoarthritis models, as well as Erastin-induced ferroptosis, through the modulation of the P53/	102
An organogold compound impairs Leishmania amazonensis amastigotes survival and delays lesion progression in murine cutaneous leishmaniasis: Mechanistic insights	101
Neuroanatomical distribution of fluorophores within adult RXFP3 Cre-tdTomato/YFP mouse brain	99
Modulation of contextual fear acquisition and extinction by acute and chronic relaxin-3 receptor (RXFP3) activation in the rat retrosplenial cortex	98
Alisol A 24-Acetate combats Methicillin-Resistant Staphylococcus aureus infection by targeting the mevalonate biosynthesis	98
PLK-3-mediated phosphorylation of BAP1 prevents diabetic retinopathy	95
Investigation of the role and mechanism of dapagliflozin in mitigating renal injury in rats afflicted with diabetic kidney disease	81
Evidence for the contribution of vasopressin V1B receptors in the pathophysiology of depression	81
ALDH1A1 confers resistance to RAF/MEK inhibitors in melanoma cells by maintaining stemness phenotype and activating PI3K/AKT signaling	81
Cytochrome P450 2E1 gene knockout or inhibition prevents obesity induced by high-fat diet via regulating energy expenditure	76
Luteolin binds Src, promotes STAT3 protein ubiquitination and exerts anti-melanoma effects in cell and mouse models	75
PXR as the tipping point between innate immune response, microbial infections, and drug metabolism	74
Peptide GLP-1 receptor agonists: From injection to oral delivery strategies	74
Excess glucocorticoid exposure contributes to adipose tissue fibrosis which involves macrophage interaction with adipose precursor cells	73

Drug-oxidizing and conjugating non-cytochrome P450 (non-P450) enzymes in cynomolgus monkeys and common marmosets as preclinical models for humans	73
Diabetes and the fabkin complex: A dual-edged sword	70
The potent role of Src kinase-regulating glucose metabolism in cancer	69
ALKBH7 mediates the mitigative effect of bismuth drug against cisplatin-induced acute kidney injury	69
Renoprotective effect of Nesfatin-1 in Adenine-Induced Chronic kidney Disease: An in vitro and in vivo study	69
AMPK-activation by catecholamines induces autophagy and cell proliferation in cardiac fibroblasts	69
HDAC6 is involved in diabetic nephropathy by regulating TGFβ/Smads and NF-κB signaling pathways	67
Editorial Board	65
Corrigendum to “Targeting AhR suppresses hepatocyte ferroptosis in MASH by regulating the Pten/Akt/β catenin axis” [Biochem. Pharmacol. 232 (2025) 116711]	63
Bile acids and bile acid activated receptors in the treatment of Covid-19	63
Methionine cycle in nonalcoholic fatty liver disease and its potential applications	60
Recent trends in fragment-based anticancer drug design strategies against different targets: A mini-review	58
Identification of a dual JAK3/TEC family kinase inhibitor for atopic dermatitis therapy	57
Unveiling ODP4: A breakthrough in PCOS treatment via BAT transplantation	57
Emerging role of m6A modification in fibrotic diseases and its potential therapeutic effect	57
Exploring tryptophan metabolism: The transition from disturbed balance to diagnostic and therapeutic potential in metabolic diseases	57
LINC00324 promotes cell proliferation and metastasis of esophageal squamous cell carcinoma through sponging miR-493-5p via MAPK signaling pathway	55
Hydroquinone destabilizes BIM mRNA through upregulation of p62 in chronic myeloid leukemia cells	53
Corrigendum to “Dose-dependent regulation of mitochondrial function and cell death pathway by sorafenib in liver cancer cells” [Biochem. Pharmacol. 176 (2020) 113902]	52
Anti-inflammatory, but not osteoprotective, effect of the TRAF6/CD40 inhibitor 6877002 in rodent models of local and systemic osteolysis	52
Provirus reactivation is impaired in HIV-1 infected individuals on treatment with dasatinib and antiretroviral therapy	51
A novel L-shaped ortho-quinone analog as PLK1 inhibitor blocks prostate cancer cells in G2 phase	51
Effects of heme oxygenase 1 in the molecular changes and neuropathy associated with type 2 diabetes in mice	51
ALA-PDT augments intense inflammation in the treatment of acne vulgaris by COX2/TREM1 mediated M1 macrophage polarization	50
Roles of microglia in Alzheimer’s disease and impact of new findings on microglial heterogeneity as a target for therapeutic intervention	48
The relationship between tumor metabolism and 5-fluorouracil resistance	47
Ammonium tetrathiomolybdate attenuates acetaminophen-induced acute liver failure by inhibiting the TRPV4/Calcium/NF-κB signaling pathway	47
MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway	47
Pharmacological inhibition of HDAC6 suppresses NLRP3 inflammasome-mediated IL-1β release	46
LILRB4 as a novel immunotherapeutic target for multiple diseases	45
The value of neck adipose tissue as a predictor for metabolic risk in health and type 2 diabetes	45
Mast cell activation induced by tamoxifen citrate via MRGPRX2 plays a potential adverse role in breast cancer treatment	45
Torachrysone-8-O-β-d-glucoside mediates anti-inflammatory effects by blocking aldose reductase-catalyzed metabolism of lipid peroxidation products	45
Potential small effector molecules restoring cellular defects due to sialic acid biosynthetic enzyme deficiency: Pathological relevance to GNE myopathy	45
Ultraviolet-treated riboflavin alleviates atopic dermatitis by inhibiting NLRP3 inflammasome activation and M1 macrophage polarization via histone lactylation	45
DEC1 deficiency promotes osteoclastic activity by augmenting NFATc1 signaling via transactivation and the Ca2+/calcineurin pathway	44
GRHL3 drives radiotherapy resistance and blocks the anti-tumor response of NK and CD4+ T cells in lung squamous cell carcinoma via RNF2	44
Targeting non-coding RNAs and N6-methyladenosine modification in hepatocellular carcinoma	43
Methyl-oxazolomycin A: A novel oxazolomycin analog with potent selective estrogen receptor degrading activity in breast cancer cells	43
Epigallocatechin gallate relieves asthmatic symptoms in mice by suppressing HIF-1α/VEGFA-mediated M2 skewing of macrophages	42
Venom composition and bioactive RF-amide peptide toxins of the saddleback caterpillar, Acharia stimulea (Lepidoptera: Limacodidae)	42
Knockdown of Galectin-9 alleviates rheumatoid arthritis through suppressing TNF-α-induced activation of fibroblast-like synoviocytes	42
Isoflavone glucoside genistin, an inhibitor targeting Sortase A and Listeriolysin O, attenuates the virulence of Listeria monocytogenes in vivo and in vitro	42
PPARα/δ dual agonist H11 alleviates diabetic kidney injury by improving the metabolic disorders of tubular epithelial cells	41
Translational potential of targeting Anoctamin-1-Encoded Calcium-Activated chloride channels in hypertension	41
Immunometabolic attributes and mitochondria-associated signaling of Tumor-Associated Macrophages in tumor microenvironment modulate cancer progression	41
Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders	40
Effect of pharmacological heart failure drugs and gene therapy on Danon's cardiomyopathy	40
Identifying inhibitors of Trypanosoma cruzi nucleoside diphosphate kinase 1 as potential repurposed drugs for Chagas’ disease	40
Itaconate alleviates β2-microglobulin-induced cognitive impairment by enhancing the hippocampal amino-β-carboxymuconate-semialdehyde-decarboxylase/picolinic acid pathway	39

Carbon monoxide in cell signaling and potential therapeutics	39
Understanding resistance acquisition by Pseudomonas aeruginosa and possible pharmacological approaches in palliating its pathogenesis	39
Macrophage scavenger receptor A1 antagonizes abdominal aortic aneurysm via upregulating IRG1	39
Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines	38
Inhibition of γ-secretase/Notch pathway as a potential therapy for reversing cancer drug resistance	38
Editorial Board	38
SIS3 suppresses osteoclastogenesis and ameliorates bone loss in ovariectomized mice by modulating Nox4-dependent reactive oxygen species	38
The role and regulation of Pnn in proliferative and non-dividing cells: Form embryogenesis to pathogenesis	38
KDM6B knockdown alleviates sleep deprivation-induced cerebrovascular lesions in APP/PS1 mice by inhibiting PARP16 expression	38
6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model	37
Physiological and pharmacological overview of the gonadotropin releasing hormone	37
Combining Sorafenib, Se-methylselenocysteine, and α-Ketoacid for synergistic cytotoxicity in Hepatocellular carcinoma cell lines	37
Astragaloside IV as a potent vWbp inhibitor: An innovative strategy to mitigate foodborne Staphylococcus aureus infections	36
Sirtuin1-p53: A potential axis for cancer therapy	36
Exploring the glycation association with dyslipidaemia: Novel approach for diabetic nephropathy	36
Recent advances in studies on FtsZ inhibitors	36
The short-chain fatty acid acetate modulates orexin/hypocretin neurons: A novel mechanism in gut-brain axis regulation of energy homeostasis and feeding	36
Serum-derived extracellular vesicles mediate acquired multidrug resistance of MCF-7 breast cancer cells induced by chemotherapeutic drugs	35
FGF2 drives osteosarcoma metastasis through activating FGFR1-4 receptor pathway-mediated ICAM-1 expression	35
The dual targeting effects of KD025 on casein kinase 2 and ROCK2 in a mouse model of diet-induced obesity	35
Immunomodulatory effects of antiangiogenic tyrosine kinase inhibitors in renal cell carcinoma models: Impact on following anti-PD-1 treatments	35
GPR55: Physiological functions and therapeutic potential in depression	34
Ursolic acid augments the chemosensitivity of drug-resistant breast cancer cells to doxorubicin by AMPK-mediated mitochondrial dysfunction	34
Circadian oscillator NPAS2 regulates diurnal expression and activity of CYP1A2 in mouse liver	34
Tumor Cells-derived exosomal CircRNAs: Novel cancer drivers, molecular mechanisms, and clinical opportunities	34
Chrysophanol prevents IL-1β-Induced inflammation and ECM degradation in osteoarthritis via the Sirt6/NF-κB and Nrf2/NF-κB axis	34
Targeting fuel pocket of cancer cell metabolism: A focus on glutaminolysis	34
Peroxisome proliferator-activated receptor (PPAR) agonists as a potential therapy for inherited metabolic disorders	33
Oleoylethanolamide alleviates hyperlipidaemia-mediated vascular calcification via attenuating mitochondrial DNA stress triggered autophagy-dependent ferroptosis by activating PPARα	33
Dual-specificity tyrosine phosphorylation-regulated kinase 1A promotes the inclusion of amyloid precursor protein exon 7	33
Human flavin-containing monooxygenase 1 and its long-sought hydroperoxyflavin intermediate	33
ALOX5 promotes autophagy-dependent ferroptosis by activating the AMPK/mTOR pathway in melanoma	32
SMURF1 leads to the β-catenin signaling-mediated progression of esophageal squamous carcinoma by losing PATZ1-induced CCNG2 transcription	32
Acyclovir resistance in herpes simplex viruses: Prevalence and therapeutic alternatives	32
Treatment with S-adenosylmethionine ameliorates irinotecan-induced intestinal barrier dysfunction and intestinal microbial disorder in mice	32
Dexmedetomidine alleviates anxiety-like behavior in mice following peripheral nerve injury by reducing the hyperactivity of glutamatergic neurons in the anterior cingulate cortex	32
Rosavidin protects against PM2.5-induced lung toxicity via inhibition of NLRP3 inflammasome-mediated pyroptosis by activating the PI3K/AKT pathway	32
Uremic toxins activate CREB/ATF1 in endothelial cells related to chronic kidney disease	32
Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo	32
Overview of the therapeutic strategies for ER positive breast cancer	31
Viral Vectors, Exosomes, and Vexosomes: Potential armamentarium for delivering CRISPR/Cas to cancer cells	31
Ponatinib exacerbate renal injury in systemic lupus erythematosus mouse model through PDGFR-PI3K/AKT pathway	31
Melatonin alleviates brain injury in copper-laden rats: Underlying benefits for Wilson’s disease	31
Corrigendum to “Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury“ [Biochem. Pharmacol. 63(1) (2002)	31
Antibody-drug conjugates for non-small cell lung cancer: Advantages and challenges in clinical translation	30
Role of sirtuins in hepatocellular carcinoma progression and multidrug resistance: Mechanistical and pharmacological perspectives	30
xCT/Slc7a11 promotes pulmonary arterial hypertension by disrupting AMPKα suppression of mTOR activation	30
Ifosfamide alleviates autoimmune toxicity and enhances antitumor efficacy in melanoma immunotherapy	30
Mitomycin induced the senescence of alveolar epithelial cells by targeting peroxiredoxin I	30
Preclinical evaluation of new drug-drug interactions of lomitapide: A proposal for novel mechanism of interaction associated with lipid metabolic changes	30
Emerging roles of senolytics/senomorphics in HIV-related co-morbidities	30
Therapeutic of a white adipose tissue-specific bivalent aptamer in obesity	30
Leptin impairs the therapeutic efficacy of adipose-derived mesenchymal stem cells by inducing apoptosis through NLRP3 inflammasomes activation	30
Targeting fibroblast activation protein with chimeric antigen receptor macrophages	30
Corrigendum to “Geraniol ameliorates acute liver failure induced by lipopolysaccharide/D-galactosamine via regulating macrophage polarization and NLRP3 inflammasome activation by PPAR-γ methylation Ge	29
P4HA3 depletion induces ferroptosis and inhibits colorectal cancer growth by stabilizing ACSL4 mRNA	29
Detailed resume of S-methyltransferases: Categories, structures, biological functions and research advancements in related pathophysiology and pharmacotherapy	29
Maladaptive regeneration and metabolic dysfunction associated steatotic liver disease: Common mechanisms and potential therapeutic targets	29
BMAL1 plays a crucial role in immune homeostasis during sepsis-induced acute lung injury	29
Engineering a long acting, non-biased relaxin agonist using Protein-in-Protein technology	29
Possibility of averting cytokine storm in SARS-COV 2 patients using specialized pro-resolving lipid mediators	28
CEMIP promotes small cell lung cancer proliferation by activation of glutamine metabolism via FBXW7/c-Myc-dependent axis	28
A rational foundation for micheliolide-based combination strategy by targeting redox and metabolic circuit in cancer cells	28
The critical roles of STING in mitochondrial homeostasis	28
Mefunidone ameliorates acute liver failure in mice by inhibiting MKK4-JNK pathway	28
Corrigendum to “DOCK2 contributes to endotoxemia-induced acute lung injury in mice by activating proinflammatory macrophages” [Biochem. Pharmacol. 184 (2021) 114399]	28
Editorial Board	28
Cytarabine-induced destabilization of MCL1 mRNA and protein triggers apoptosis in leukemia cells	28
IOX-1 suppresses metastasis of osteosarcoma by upregulating histone H3 lysine trimethylation	28
Structure and function of the highly homologous deubiquitinases ubiquitin specific peptidase 25 and 28: Insights into their pathophysiological and therapeutic roles	28
Positive programming of the GC-IGF1 axis mediates adult osteoporosis susceptibility in male offspring rats induced by prenatal dexamethasone exposure	28
SIRT6 regulates endothelium-dependent relaxation by modulating nitric oxide synthase 3 (NOS3)	28
PCSK9 regulates myofibroblast transformation through the JAK2/STAT3 pathway to regulate fibrosis after myocardial infarction	27
Editorial Board	27
Mithramycin suppresses tumor growth by regulating CD47 and PD-L1 expression	27
Chronic kidney disease-induced muscle atrophy: Molecular mechanisms and promising therapies	27
Role of sodium taurocholate cotransporting polypeptide (NTCP) in HBV-induced hepatitis: Opportunities for developing novel therapeutics	27
Novel DCPIB analogs as dual inhibitors of VRAC/TREK1 channels reduced cGAS-STING mediated interferon responses	27
Finding new analgesics: Computational pharmacology faces drug discovery challenges	27
Protein prenylation in islet β-cell function in health and metabolic stress	27

A review on the effect of COX-2-mediated mechanisms on development and progression of gastric cancer induced by nicotine	27
MiR-466b-3p/HDAC7 meditates transgenerational inheritance of testicular testosterone synthesis inhibition induced by prenatal dexamethasone exposure	27
m6A modification impacts hepatic drug and lipid metabolism properties by regulating carboxylesterase 2	27
Targeting regulated chondrocyte death in osteoarthritis therapy	27
Editorial Board	27
TNFα blockade reverses vascular and uteroplacental matrix metalloproteinases imbalance and collagen accumulation in hypertensive pregnant rats	27
Mitochondrial elongation confers protection against doxorubicin-induced cardiotoxicity	27
Differential contribution of renal cytochrome P450 enzymes to kidney endothelial dysfunction and vascular oxidative stress in obesity	27
Macrophage-derived human resistin promotes perivascular adipose tissue dysfunction in experimental inflammatory arthritis	27
Metabolic activation of drugs by cytochrome P450 enzymes: Biochemical insights into mechanism-based inactivation by fibroblast growth factor receptor inhibitors and chemical approaches to attenuate re	26
Glucocorticoids and natural killer cells: A suppressive relationship	26
Citrulline activates adenosine receptors: New insight into metabolic pathways interaction	26
Redox regulation by carotenoids: Evidence and conflicts for their application in cancer	26
Eicosatrienoic acid inhibits estradiol synthesis through the CD36/FOXO1/CYP19A1 signaling pathway to improve PCOS in mice	26
Sterol regulation of developmental and oncogenic Hedgehog signaling	26
3-Hydroxybutyrate ameliorates sepsis-associated acute lung injury by promoting autophagy through the activation of GPR109α in macrophages	25
Extracellular nucleotides in smooth muscle contraction	25
The increasing role of pigment epithelium-derived factor in metastasis: from biological importance to a promising target	25
Structure-based optimization of Toddacoumalone as highly potent and selective PDE4 inhibitors with anti-inflammatory effects	25
Corrigendum to “Cardioprotective effects of melatonin and metformin against doxorubicin-induced cardiotoxicity in rats are through preserving mitochondrial function and dynamics” [Biochem. Pharmacol.	25
An A-ring substituted evodiamine derivative with potent anticancer activity against human non-small cell lung cancer cells by targeting heat shock protein 70	25
Novel pharmacological inhibition of JMJD3 improves necrotizing enterocolitis by attenuating the inflammatory response and ameliorating intestinal injury	25
Azithromycin modulates Teff/Treg balance in retinal inflammation via the mTOR signaling pathway	25
Design and characterization of a triazole-based growth hormone secretagogue receptor modulator inhibiting the glucoregulatory and feeding actions of ghrelin	25
Corrigendum to “TTI-101: A competitive inhibitor of STAT3 that spares oxidative phosphorylation and reverses mechanical allodynia in mouse models of neuropathic pain” [Biochem. Pharmacol. 192 (2021) 1	25
Animal models of acute lymphoblastic leukemia: Recapitulating the human disease to evaluate drug efficacy and discover therapeutic targets	25
Cardiac human bitter taste receptors contain naturally occurring variants that alter function	25
Inhibition of soluble epoxide hydrolase relieves adipose inflammation via modulating M1/M2 macrophage polarization to alleviate airway inflammation and hyperresponsiveness in obese asthma	25
FXR agonists for colorectal and liver cancers, as a stand-alone or in combination therapy	24
Neuroactive steroids, WIN-compounds and cholesterol share a common binding site on muscarinic acetylcholine receptors	24
Polo-like kinase 1 (PLK1) is a novel CARD14-binding protein in keratinocytes	24
Therapeutic targeting of Wnt antagonists by small molecules for treatment of osteoporosis	24
Biology and pharmacology of platelet-type 12-lipoxygenase in platelets, cancer cells, and their crosstalk	24
Role of long non-coding RNAs in adipose tissue metabolism and associated pathologies	24
Integrated metabolomics and transcriptomics reveal the neuroprotective effect of nervonic acid on LPS-induced AD model mice	24
Targeted delivery of a colchicine analogue provides synergy with ATR inhibition in cancer cells	24
Curing childhood cancer the “Natural” Way: Nature as the source of chemotherapy agents	24
Selpercatinib attenuates bleomycin-induced pulmonary fibrosis by inhibiting the TGF-β1 signaling pathway	24
Cancer stem cells: Recent insights and therapies	24
Enhanced thermogenesis in PAS Kinase-deficient male mice	23
Quassinoid analogs exert potent antitumor activity via reversible protein biosynthesis inhibition in human colorectal cancer	23
Ubiquitin ligase TRIM63 regulates HOXA10 expression to mediate fatty acid β-oxidation and suppress lung adenocarcinoma metastasis	23
miR-486-5p-rich extracellular vesicles derived from patients with olanzapine-induced insulin resistance negatively affect glucose-regulating function	23
Canonical DDR activation by EMT inducing agent 5-Fluorouracil is modulated by a cannabinoid based combinatorial approach via inducing autophagy and suppression of vimentin expression	23
Mst1 inhibition mitigates steroid-induced femoral head osteonecrosis by modulating autophagy in bone microvascular endothelial cells	23
Resolvin D3 improves the impairment of insulin signaling in skeletal muscle and nonalcoholic fatty liver disease through AMPK/autophagy-associated attenuation of ER stress	23
Implication of Let7b/AhR/ARNT/HMGB1/RAGE cascade in neuroplasticity disturbances induced by glucocorticoids and the promising reversible effect of 3,3 diindolymethane: Bidirectional crosstalk of Aryl	23
Anti-inflammatory mechanism of the MLKL inhibitor necrosulfonamide in LPS- or poly(I:C)-induced neuroinflammation and necroptosis	23
PPARγ activation by fisetin mitigates vascular smooth muscle cell senescence via the mTORC2-FoxO3a-autophagy signaling pathway	23
Activated microglia secretome and proinflammatory cytokines increase neuronal mu-opioid receptor signalling and expression	22
Enterogastric and enterohepatic recycling of dendrobine in rats: a novel disposition mechanism responsible for pharmacokinetic multiple peaks	22
Vesicular monoamine transporter-2 inhibitor JPC-141 prevents methamphetamine-induced dopamine toxicity and blocks methamphetamine self-administration in rats	22
Jolkinolide B synergistically potentiates the antitumor activity of GPX4 inhibitors via inhibiting TrxR1 in cisplatin-resistant bladder cancer cells	22
Triflupromazine and tranylcypromine alleviate primary cisplatin resistance in lung adenocarcinoma by promoting LDHA-mediated AMBRA1 ubiquitination	22
Omega-3 polyunsaturated fatty acids alleviate hyperuricemic nephropathy by inhibiting renal pyroptosis through GPR120	22
The role of taurine through endoplasmic reticulum in physiology and pathology	22
Calcium saccharate/DUSP6 suppresses renal cell carcinoma glycolytic metabolism and boosts sunitinib efficacy via the ERK-AKT pathway	22
Metallodrugs: Synthesis, mechanism of action and nanoencapsulation for targeted chemotherapy	22
Detailed functional characterization of four nanobodies as positive allosteric modulators of the human calcium-sensing receptor	22
Pathogenic mitochondrial dysfunction and metabolic abnormalities	22
Delineating the tumour-regulatory roles of EYA4	22
Mechanotransduction and the extracellular matrix: Key drivers of lung pathologies and drug responsiveness	22
AdipoRon and ADP355, adiponectin receptor agonists, in Metabolic-associated Fatty Liver Disease (MAFLD) and Nonalcoholic Steatohepatitis (NASH): A systematic review	22
TFAP2A is involved in neuropathic pain by regulating Grin1 expression in glial cells of the dorsal root ganglion	22
Discovery of novel carboxylesterase 2 inhibitors for the treatment of delayed diarrhea and ulcerative colitis	22
Flavokawain B is an effective natural peroxisome proliferator-activated receptor γ-selective agonist with a strong glucose-lowering effect	22
A systematic review and meta-analysis of environmental contaminant exposure impacts on weight loss and glucose regulation during calorie-restricted diets in preclinical studies: Persistent organic pol	22
Oridonin combined with cisplatin synergistically induces apoptosis by activating the NOXA-BCL2 axis in esophageal squamous cell carcinoma	22
Regulatory roles of CARD9-BCL10-Rac1 (CBR) signalome in islet β-cell function in health and metabolic stress: Is there room for MALT1?	21
Corrigendum to “Resveratrol inhibits epithelial-mesenchymal transition and renal fibrosis by antagonizing the hedgehog signaling pathway” [Biochem. Pharmacol. 92 (2014) 484–493]	21
A small molecule compound that inhibits blue light-induced retinal damage via activation of autophagy	21
Acknowledgment	21
Editorial Board	21
Corrigendum to “Apoptotic effects of mahanine on human leukemic cells are mediated through crosstalk between Apo-1/Fas signaling and the Bid protein and via mitochondrial pathways” [Biochem. Pharmacol	21
Activation of aryl hydrocarbon receptor by azatyrosine-phenylbutyric hydroxamide inhibits progression of diabetic retinopathy mice	21
Antiplatelet drug ticagrelor suppresses triple negative breast cancer metastasis by targeting PI3K	21
Inhibition of proteasome, but not lysosome, upregulates organic anion transporter 3 in vitro and in vivo	21
Bisphenol-A analogs induce lower urinary tract dysfunction in male mice	21
Sonidegib potentiates the cancer cells’ sensitivity to cytostatic agents by functional inhibition of ABCB1 and ABCG2 in vitro and ex vivo	21
Editorial Board	21
The blockade of neddylation alleviates ventilator-induced lung injury by reducing stretch-induced damage to pulmonary epithelial cells	21
Advancements in age-related macular degeneration treatment: From traditional anti-VEGF to emerging therapies in gene, stem cell, and nanotechnology	21
Luxeptinib disables NLRP3 inflammasome-mediated IL-1β release and pathways required for secretion of inflammatory cytokines IL-6 and TNFα	21
Arylacetamide deacetylase knockout mice are sensitive to ketoconazole-induced hepatotoxicity and adrenal insufficiency	21
Differential regulation of histamine H1 receptor-mediated ERK phosphorylation by Gq proteins and arrestins	21
Selective stabilization of the intermediate inactivated Na+ channel by the new-generation anticonvulsant rufinamide	21
Estrogen dampens central cannabinoid receptor 1-mediated neuroexcitation and pressor response in conscious female rats	21
A high affinity Sybody blocks Cofilin-1 binding to F-actin in vitro and in cancer cells	21
Histone lactylation-driven YTHDF2 promotes non-small cell lung cancer cell glycolysis and stemness by recognizing m6A modification of SFRP2	20
Nicotinamide riboside alleviates brain dysfunction induced by chronic cerebral hypoperfusion via protecting mitochondria	20
AMPK activation attenuates HER3 upregulation and Neuregulin-Mediated rescue of cell proliferation in HER2-Overexpressing breast cancer cell lines exposed to lapatinib	20
Targeting epigenetics as a promising therapeutic strategy for treatment of neurodegenerative diseases	20
Function and inhibition of DYRK1A: Emerging roles of treating multiple human diseases	20
Necroptosis: a significant and promising target for intervention of cardiovascular disease	20
Inhibition of FABP5 attenuates inflammatory bowel disease by modulating macrophage alternative activation	20