Biochemical Pharmacology

Article	Citations
Corrigendum to “Dose-dependent regulation of mitochondrial function and cell death pathway by sorafenib in liver cancer cells” [Biochem. Pharmacol. 176 (2020) 113902]	219
Hydroquinone destabilizes BIM mRNA through upregulation of p62 in chronic myeloid leukemia cells	193
A novel L-shaped ortho-quinone analog as PLK1 inhibitor blocks prostate cancer cells in G2 phase	163
Editorial Board	162
Inhibition of circular RNA ASPH reduces the proliferation and promotes the apoptosis of hepatic stellate cells in hepatic fibrosis	155
CircDUSP16 mediates the effect of triple-negative breast cancer in pirarubicin via the miR-1224-3p/TFDP2 axis	139
The potent role of Src kinase-regulating glucose metabolism in cancer	135
Identification of a dual JAK3/TEC family kinase inhibitor for atopic dermatitis therapy	127
Evidence for the contribution of vasopressin V1B receptors in the pathophysiology of depression	126
LINC00324 promotes cell proliferation and metastasis of esophageal squamous cell carcinoma through sponging miR-493-5p via MAPK signaling pathway	121
Neuroanatomical distribution of fluorophores within adult RXFP3 Cre-tdTomato/YFP mouse brain	119
Modulation of contextual fear acquisition and extinction by acute and chronic relaxin-3 receptor (RXFP3) activation in the rat retrosplenial cortex	114
Alisol A 24-Acetate combats Methicillin-Resistant Staphylococcus aureus infection by targeting the mevalonate biosynthesis	105
Anti-inflammatory, but not osteoprotective, effect of the TRAF6/CD40 inhibitor 6877002 in rodent models of local and systemic osteolysis	100
PLK-3-mediated phosphorylation of BAP1 prevents diabetic retinopathy	98
Effects of heme oxygenase 1 in the molecular changes and neuropathy associated with type 2 diabetes in mice	97
Metformin exhibits inhibitory effects on ferroptosis and alleviates chondrocyte metabolic imbalance in osteoarthritis models, as well as Erastin-induced ferroptosis, through the modulation of the P53/	93
Diabetes and the fabkin complex: A dual-edged sword	92
Luteolin binds Src, promotes STAT3 protein ubiquitination and exerts anti-melanoma effects in cell and mouse models	91
An organogold compound impairs Leishmania amazonensis amastigotes survival and delays lesion progression in murine cutaneous leishmaniasis: Mechanistic insights	80
Excess glucocorticoid exposure contributes to adipose tissue fibrosis which involves macrophage interaction with adipose precursor cells	75
MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway	74
Exploring tryptophan metabolism: The transition from disturbed balance to diagnostic and therapeutic potential in metabolic diseases	74
Unveiling ODP4: A breakthrough in PCOS treatment via BAT transplantation	72
Bile acids and bile acid activated receptors in the treatment of Covid-19	71

Design, synthesis and anti-tumor activity of novel benzothiophenonaphthalimide derivatives targeting mitochondrial DNA (mtDNA) G-quadruplex	70
Provirus reactivation is impaired in HIV-1 infected individuals on treatment with dasatinib and antiretroviral therapy	70
Renoprotective effect of Nesfatin-1 in Adenine-Induced Chronic kidney Disease: An in vitro and in vivo study	69
Peptide GLP-1 receptor agonists: From injection to oral delivery strategies	68
Ultraviolet-treated riboflavin alleviates atopic dermatitis by inhibiting NLRP3 inflammasome activation and M1 macrophage polarization via histone lactylation	68
Sleep during COVID-19 lockdown: A cross-cultural study investigating job system relevance	68
PGC‐1α activation ameliorates cancer-induced bone pain via inhibiting apoptosis of GABAergic interneurons	67
Cytochrome P450 2E1 gene knockout or inhibition prevents obesity induced by high-fat diet via regulating energy expenditure	63
Methionine cycle in nonalcoholic fatty liver disease and its potential applications	63
Editorial Board	62
AMPK-activation by catecholamines induces autophagy and cell proliferation in cardiac fibroblasts	61
ALKBH7 mediates the mitigative effect of bismuth drug against cisplatin-induced acute kidney injury	61
HDAC6 is involved in diabetic nephropathy by regulating TGFβ/Smads and NF-κB signaling pathways	59
Corrigendum to “Targeting AhR suppresses hepatocyte ferroptosis in MASH by regulating the Pten/Akt/β catenin axis” [Biochem. Pharmacol. 232 (2025) 116711]	57
CD73 mitigates hepatic damage in alcoholic steatohepatitis by regulating PI3K/AKT-mediated hepatocyte pyroptosis	56
CDP-choline modulates cholinergic signaling and gut microbiota to alleviate DSS-induced inflammatory bowel disease	55
A variety of cytochrome P450 enzymes and flavin-containing monooxygenases in dogs and pigs commonly used as preclinical animal models	54
PXR as the tipping point between innate immune response, microbial infections, and drug metabolism	53
Investigation of the role and mechanism of dapagliflozin in mitigating renal injury in rats afflicted with diabetic kidney disease	53
Decreased HMGB1 expression contributed to cutaneous toxicity caused by lapatinib	51
Influence of tumor microenvironment on the different breast cancer subtypes and applied therapies	51
Recent trends in fragment-based anticancer drug design strategies against different targets: A mini-review	51
Pharmacological inhibition of HDAC6 suppresses NLRP3 inflammasome-mediated IL-1β release	50
Ammonium tetrathiomolybdate attenuates acetaminophen-induced acute liver failure by inhibiting the TRPV4/Calcium/NF-κB signaling pathway	50
Roles of microglia in Alzheimer’s disease and impact of new findings on microglial heterogeneity as a target for therapeutic intervention	49
Interplay between the renin angiotensin system and oxidative stress contributes to alcohol addiction by stimulating dopamine accumulation in the mesolimbic pathway	47
ALDH1A1 confers resistance to RAF/MEK inhibitors in melanoma cells by maintaining stemness phenotype and activating PI3K/AKT signaling	47
The relationship between tumor metabolism and 5-fluorouracil resistance	46
Drug-oxidizing and conjugating non-cytochrome P450 (non-P450) enzymes in cynomolgus monkeys and common marmosets as preclinical models for humans	46
Emerging role of m6A modification in fibrotic diseases and its potential therapeutic effect	45
ALA-PDT augments intense inflammation in the treatment of acne vulgaris by COX2/TREM1 mediated M1 macrophage polarization	44
Mast cell activation induced by tamoxifen citrate via MRGPRX2 plays a potential adverse role in breast cancer treatment	43
The value of neck adipose tissue as a predictor for metabolic risk in health and type 2 diabetes	43
LILRB4 as a novel immunotherapeutic target for multiple diseases	43
Torachrysone-8-O-β-d-glucoside mediates anti-inflammatory effects by blocking aldose reductase-catalyzed metabolism of lipid peroxidation products	43
Circadian oscillator NPAS2 regulates diurnal expression and activity of CYP1A2 in mouse liver	43
Knockdown of Galectin-9 alleviates rheumatoid arthritis through suppressing TNF-α-induced activation of fibroblast-like synoviocytes	43
Potential small effector molecules restoring cellular defects due to sialic acid biosynthetic enzyme deficiency: Pathological relevance to GNE myopathy	43
Targeting non-coding RNAs and N6-methyladenosine modification in hepatocellular carcinoma	42
DEC1 deficiency promotes osteoclastic activity by augmenting NFATc1 signaling via transactivation and the Ca2+/calcineurin pathway	42
Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines	42
GRHL3 drives radiotherapy resistance and blocks the anti-tumor response of NK and CD4+ T cells in lung squamous cell carcinoma via RNF2	42
Methyl-oxazolomycin A: A novel oxazolomycin analog with potent selective estrogen receptor degrading activity in breast cancer cells	41
Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo	41
Rosavidin protects against PM2.5-induced lung toxicity via inhibition of NLRP3 inflammasome-mediated pyroptosis by activating the PI3K/AKT pathway	41
Human flavin-containing monooxygenase 1 and its long-sought hydroperoxyflavin intermediate	41
SIS3 suppresses osteoclastogenesis and ameliorates bone loss in ovariectomized mice by modulating Nox4-dependent reactive oxygen species	41
Melatonin alleviates brain injury in copper-laden rats: Underlying benefits for Wilson’s disease	40
Dexmedetomidine alleviates anxiety-like behavior in mice following peripheral nerve injury by reducing the hyperactivity of glutamatergic neurons in the anterior cingulate cortex	39
Ursolic acid augments the chemosensitivity of drug-resistant breast cancer cells to doxorubicin by AMPK-mediated mitochondrial dysfunction	39

Carbon monoxide in cell signaling and potential therapeutics	39
Inhibition of γ-secretase/Notch pathway as a potential therapy for reversing cancer drug resistance	39
Treatment with S-adenosylmethionine ameliorates irinotecan-induced intestinal barrier dysfunction and intestinal microbial disorder in mice	39
Viral Vectors, Exosomes, and Vexosomes: Potential armamentarium for delivering CRISPR/Cas to cancer cells	39
Uremic toxins activate CREB/ATF1 in endothelial cells related to chronic kidney disease	38
Epigallocatechin gallate relieves asthmatic symptoms in mice by suppressing HIF-1α/VEGFA-mediated M2 skewing of macrophages	38
FGF2 drives osteosarcoma metastasis through activating FGFR1-4 receptor pathway-mediated ICAM-1 expression	37
Targeting fuel pocket of cancer cell metabolism: A focus on glutaminolysis	37
The role and regulation of Pnn in proliferative and non-dividing cells: Form embryogenesis to pathogenesis	37
SMURF1 leads to the β-catenin signaling-mediated progression of esophageal squamous carcinoma by losing PATZ1-induced CCNG2 transcription	37
ALOX5 promotes autophagy-dependent ferroptosis by activating the AMPK/mTOR pathway in melanoma	37
Understanding resistance acquisition by Pseudomonas aeruginosa and possible pharmacological approaches in palliating its pathogenesis	36
Editorial Board	36
Macrophage scavenger receptor A1 antagonizes abdominal aortic aneurysm via upregulating IRG1	35
KDM6B knockdown alleviates sleep deprivation-induced cerebrovascular lesions in APP/PS1 mice by inhibiting PARP16 expression	35
Effect of pharmacological heart failure drugs and gene therapy on Danon's cardiomyopathy	35
Physiological and pharmacological overview of the gonadotropin releasing hormone	35
Astragaloside IV as a potent vWbp inhibitor: An innovative strategy to mitigate foodborne Staphylococcus aureus infections	34
Itaconate alleviates β2-microglobulin-induced cognitive impairment by enhancing the hippocampal amino-β-carboxymuconate-semialdehyde-decarboxylase/picolinic acid pathway	34
Combining Sorafenib, Se-methylselenocysteine, and α-Ketoacid for synergistic cytotoxicity in Hepatocellular carcinoma cell lines	34
6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model	34
Translational potential of targeting Anoctamin-1-Encoded Calcium-Activated chloride channels in hypertension	34
The dual targeting effects of KD025 on casein kinase 2 and ROCK2 in a mouse model of diet-induced obesity	33
Serum-derived extracellular vesicles mediate acquired multidrug resistance of MCF-7 breast cancer cells induced by chemotherapeutic drugs	33
Isoflavone glucoside genistin, an inhibitor targeting Sortase A and Listeriolysin O, attenuates the virulence of Listeria monocytogenes in vivo and in vitro	33
Chrysophanol prevents IL-1β-Induced inflammation and ECM degradation in osteoarthritis via the Sirt6/NF-κB and Nrf2/NF-κB axis	33
Immunomodulatory effects of antiangiogenic tyrosine kinase inhibitors in renal cell carcinoma models: Impact on following anti-PD-1 treatments	32
Identifying inhibitors of Trypanosoma cruzi nucleoside diphosphate kinase 1 as potential repurposed drugs for Chagas’ disease	32
Dual-specificity tyrosine phosphorylation-regulated kinase 1A promotes the inclusion of amyloid precursor protein exon 7	32
Tumor Cells-derived exosomal CircRNAs: Novel cancer drivers, molecular mechanisms, and clinical opportunities	32
The short-chain fatty acid acetate modulates orexin/hypocretin neurons: A novel mechanism in gut-brain axis regulation of energy homeostasis and feeding	32
Venom composition and bioactive RF-amide peptide toxins of the saddleback caterpillar, Acharia stimulea (Lepidoptera: Limacodidae)	32
Sirtuin1-p53: A potential axis for cancer therapy	32
Immunometabolic attributes and mitochondria-associated signaling of Tumor-Associated Macrophages in tumor microenvironment modulate cancer progression	31
PPARα/δ dual agonist H11 alleviates diabetic kidney injury by improving the metabolic disorders of tubular epithelial cells	31
Acyclovir resistance in herpes simplex viruses: Prevalence and therapeutic alternatives	31
Recent advances in studies on FtsZ inhibitors	31
Oleoylethanolamide alleviates hyperlipidaemia-mediated vascular calcification via attenuating mitochondrial DNA stress triggered autophagy-dependent ferroptosis by activating PPARα	31
Peroxisome proliferator-activated receptor (PPAR) agonists as a potential therapy for inherited metabolic disorders	31
Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders	31
Exploring the glycation association with dyslipidaemia: Novel approach for diabetic nephropathy	31
Leptin impairs the therapeutic efficacy of adipose-derived mesenchymal stem cells by inducing apoptosis through NLRP3 inflammasomes activation	30
Corrigendum to “Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury“ [Biochem. Pharmacol. 63(1) (2002)	30
Ifosfamide alleviates autoimmune toxicity and enhances antitumor efficacy in melanoma immunotherapy	30
Mitomycin induced the senescence of alveolar epithelial cells by targeting peroxiredoxin I	30
Preclinical evaluation of new drug-drug interactions of lomitapide: A proposal for novel mechanism of interaction associated with lipid metabolic changes	29
Targeting fibroblast activation protein with chimeric antigen receptor macrophages	29
Emerging roles of senolytics/senomorphics in HIV-related co-morbidities	29
Cytarabine-induced destabilization of MCL1 mRNA and protein triggers apoptosis in leukemia cells	29
xCT/Slc7a11 promotes pulmonary arterial hypertension by disrupting AMPKα suppression of mTOR activation	29
Maladaptive regeneration and metabolic dysfunction associated steatotic liver disease: Common mechanisms and potential therapeutic targets	29
Role of sirtuins in hepatocellular carcinoma progression and multidrug resistance: Mechanistical and pharmacological perspectives	29
Mitochondrial elongation confers protection against doxorubicin-induced cardiotoxicity	28
TNFα blockade reverses vascular and uteroplacental matrix metalloproteinases imbalance and collagen accumulation in hypertensive pregnant rats	28
Editorial Board	28
Structure and function of the highly homologous deubiquitinases ubiquitin specific peptidase 25 and 28: Insights into their pathophysiological and therapeutic roles	28
m6A modification impacts hepatic drug and lipid metabolism properties by regulating carboxylesterase 2	28
Mithramycin suppresses tumor growth by regulating CD47 and PD-L1 expression	28
A review on the effect of COX-2-mediated mechanisms on development and progression of gastric cancer induced by nicotine	28
Corrigendum to “Geraniol ameliorates acute liver failure induced by lipopolysaccharide/D-galactosamine via regulating macrophage polarization and NLRP3 inflammasome activation by PPAR-γ methylation Ge	28
P4HA3 depletion induces ferroptosis and inhibits colorectal cancer growth by stabilizing ACSL4 mRNA	28
Corrigendum to “DOCK2 contributes to endotoxemia-induced acute lung injury in mice by activating proinflammatory macrophages” [Biochem. Pharmacol. 184 (2021) 114399]	28
Possibility of averting cytokine storm in SARS-COV 2 patients using specialized pro-resolving lipid mediators	28
A rational foundation for micheliolide-based combination strategy by targeting redox and metabolic circuit in cancer cells	27
Positive programming of the GC-IGF1 axis mediates adult osteoporosis susceptibility in male offspring rats induced by prenatal dexamethasone exposure	27
Novel DCPIB analogs as dual inhibitors of VRAC/TREK1 channels reduced cGAS-STING mediated interferon responses	27
Macrophage-derived human resistin promotes perivascular adipose tissue dysfunction in experimental inflammatory arthritis	27
Protein prenylation in islet β-cell function in health and metabolic stress	27
Overview of the therapeutic strategies for ER positive breast cancer	27
SIRT6 regulates endothelium-dependent relaxation by modulating nitric oxide synthase 3 (NOS3)	27
Ponatinib exacerbate renal injury in systemic lupus erythematosus mouse model through PDGFR-PI3K/AKT pathway	27
MiR-466b-3p/HDAC7 meditates transgenerational inheritance of testicular testosterone synthesis inhibition induced by prenatal dexamethasone exposure	27
The critical roles of STING in mitochondrial homeostasis	27
Finding new analgesics: Computational pharmacology faces drug discovery challenges	27
Antibody-drug conjugates for non-small cell lung cancer: Advantages and challenges in clinical translation	26
Differential contribution of renal cytochrome P450 enzymes to kidney endothelial dysfunction and vascular oxidative stress in obesity	26
Targeting hematopoietic progenitor kinase 1 (HPK1) for tumor immunotherapy: advances in small molecule inhibitors	26
Therapeutic of a white adipose tissue-specific bivalent aptamer in obesity	26
Role of sodium taurocholate cotransporting polypeptide (NTCP) in HBV-induced hepatitis: Opportunities for developing novel therapeutics	26
IOX-1 suppresses metastasis of osteosarcoma by upregulating histone H3 lysine trimethylation	26

Detailed resume of S-methyltransferases: Categories, structures, biological functions and research advancements in related pathophysiology and pharmacotherapy	26
CEMIP promotes small cell lung cancer proliferation by activation of glutamine metabolism via FBXW7/c-Myc-dependent axis	26
Targeting regulated chondrocyte death in osteoarthritis therapy	26
BMAL1 plays a crucial role in immune homeostasis during sepsis-induced acute lung injury	26
Mefunidone ameliorates acute liver failure in mice by inhibiting MKK4-JNK pathway	26
Engineering a long acting, non-biased relaxin agonist using Protein-in-Protein technology	25
Structure-based optimization of Toddacoumalone as highly potent and selective PDE4 inhibitors with anti-inflammatory effects	25
Design and characterization of a triazole-based growth hormone secretagogue receptor modulator inhibiting the glucoregulatory and feeding actions of ghrelin	25
Corrigendum to “Cardioprotective effects of melatonin and metformin against doxorubicin-induced cardiotoxicity in rats are through preserving mitochondrial function and dynamics” [Biochem. Pharmacol.	25
Polo-like kinase 1 (PLK1) is a novel CARD14-binding protein in keratinocytes	25
PCSK9 regulates myofibroblast transformation through the JAK2/STAT3 pathway to regulate fibrosis after myocardial infarction	25
Editorial Board	25
Eicosatrienoic acid inhibits estradiol synthesis through the CD36/FOXO1/CYP19A1 signaling pathway to improve PCOS in mice	25
Azithromycin modulates Teff/Treg balance in retinal inflammation via the mTOR signaling pathway	25
Chronic kidney disease-induced muscle atrophy: Molecular mechanisms and promising therapies	25
Editorial Board	25
Citrulline activates adenosine receptors: New insight into metabolic pathways interaction	25
Corrigendum to “TTI-101: A competitive inhibitor of STAT3 that spares oxidative phosphorylation and reverses mechanical allodynia in mouse models of neuropathic pain” [Biochem. Pharmacol. 192 (2021) 1	25
The increasing role of pigment epithelium-derived factor in metastasis: from biological importance to a promising target	25
Implication of Let7b/AhR/ARNT/HMGB1/RAGE cascade in neuroplasticity disturbances induced by glucocorticoids and the promising reversible effect of 3,3 diindolymethane: Bidirectional crosstalk of Aryl	24
Anti-inflammatory mechanism of the MLKL inhibitor necrosulfonamide in LPS- or poly(I:C)-induced neuroinflammation and necroptosis	24
Targeted delivery of a colchicine analogue provides synergy with ATR inhibition in cancer cells	24
FXR agonists for colorectal and liver cancers, as a stand-alone or in combination therapy	24
Triflupromazine and tranylcypromine alleviate primary cisplatin resistance in lung adenocarcinoma by promoting LDHA-mediated AMBRA1 ubiquitination	24
miR-486-5p-rich extracellular vesicles derived from patients with olanzapine-induced insulin resistance negatively affect glucose-regulating function	24
Novel pharmacological inhibition of JMJD3 improves necrotizing enterocolitis by attenuating the inflammatory response and ameliorating intestinal injury	24
Enhanced thermogenesis in PAS Kinase-deficient male mice	24
PPARγ activation by fisetin mitigates vascular smooth muscle cell senescence via the mTORC2-FoxO3a-autophagy signaling pathway	24
Enterogastric and enterohepatic recycling of dendrobine in rats: a novel disposition mechanism responsible for pharmacokinetic multiple peaks	24
Selpercatinib attenuates bleomycin-induced pulmonary fibrosis by inhibiting the TGF-β1 signaling pathway	24
Quassinoid analogs exert potent antitumor activity via reversible protein biosynthesis inhibition in human colorectal cancer	24
Sterol regulation of developmental and oncogenic Hedgehog signaling	24
Canonical DDR activation by EMT inducing agent 5-Fluorouracil is modulated by a cannabinoid based combinatorial approach via inducing autophagy and suppression of vimentin expression	24
Mst1 inhibition mitigates steroid-induced femoral head osteonecrosis by modulating autophagy in bone microvascular endothelial cells	23
Metabolic activation of drugs by cytochrome P450 enzymes: Biochemical insights into mechanism-based inactivation by fibroblast growth factor receptor inhibitors and chemical approaches to attenuate re	23
Biology and pharmacology of platelet-type 12-lipoxygenase in platelets, cancer cells, and their crosstalk	23
Spectral sensitivity of circadian phase resetting, melatonin suppression and acute alerting effects of intermittent light exposure	23
Inhibition of soluble epoxide hydrolase relieves adipose inflammation via modulating M1/M2 macrophage polarization to alleviate airway inflammation and hyperresponsiveness in obese asthma	23
Delineating the tumour-regulatory roles of EYA4	23
Mechanotransduction and the extracellular matrix: Key drivers of lung pathologies and drug responsiveness	23
A systematic review and meta-analysis of environmental contaminant exposure impacts on weight loss and glucose regulation during calorie-restricted diets in preclinical studies: Persistent organic pol	23
Oridonin combined with cisplatin synergistically induces apoptosis by activating the NOXA-BCL2 axis in esophageal squamous cell carcinoma	23
Animal models of acute lymphoblastic leukemia: Recapitulating the human disease to evaluate drug efficacy and discover therapeutic targets	23
Ubiquitin ligase TRIM63 regulates HOXA10 expression to mediate fatty acid β-oxidation and suppress lung adenocarcinoma metastasis	23
Omega-3 polyunsaturated fatty acids alleviate hyperuricemic nephropathy by inhibiting renal pyroptosis through GPR120	23
Redox regulation by carotenoids: Evidence and conflicts for their application in cancer	23
Therapeutic targeting of Wnt antagonists by small molecules for treatment of osteoporosis	23
Metallodrugs: Synthesis, mechanism of action and nanoencapsulation for targeted chemotherapy	23
Role of long non-coding RNAs in adipose tissue metabolism and associated pathologies	22
Is REM sleep a paradoxical state?: Different neurons are activated in the cingulate cortices and the claustrum during wakefulness and paradoxical sleep hypersomnia	22
Resolvin D3 improves the impairment of insulin signaling in skeletal muscle and nonalcoholic fatty liver disease through AMPK/autophagy-associated attenuation of ER stress	22
Calcium saccharate/DUSP6 suppresses renal cell carcinoma glycolytic metabolism and boosts sunitinib efficacy via the ERK-AKT pathway	22
Cancer stem cells: Recent insights and therapies	22
Pathogenic mitochondrial dysfunction and metabolic abnormalities	22
Extracellular nucleotides in smooth muscle contraction	22
The role of taurine through endoplasmic reticulum in physiology and pathology	22
Discovery of novel carboxylesterase 2 inhibitors for the treatment of delayed diarrhea and ulcerative colitis	22
Piezo1 promotes colitis progression by modulating the Nrf2/NF-κB/NLRP3 signaling pathway	22
Curing childhood cancer the “Natural” Way: Nature as the source of chemotherapy agents	22
Glucocorticoids and natural killer cells: A suppressive relationship	22
Cardiac human bitter taste receptors contain naturally occurring variants that alter function	22
Activated microglia secretome and proinflammatory cytokines increase neuronal mu-opioid receptor signalling and expression	22
Harmine suppresses pancreatic cancer through DYRK1A-mediated hyper-activated RAS/MAPK inhibition	22
Inhibition of proteasome, but not lysosome, upregulates organic anion transporter 3 in vitro and in vivo	21
Neuroactive steroids, WIN-compounds and cholesterol share a common binding site on muscarinic acetylcholine receptors	21
An A-ring substituted evodiamine derivative with potent anticancer activity against human non-small cell lung cancer cells by targeting heat shock protein 70	21
Editorial Board	21
Vesicular monoamine transporter-2 inhibitor JPC-141 prevents methamphetamine-induced dopamine toxicity and blocks methamphetamine self-administration in rats	21
Corrigendum to “Apoptotic effects of mahanine on human leukemic cells are mediated through crosstalk between Apo-1/Fas signaling and the Bid protein and via mitochondrial pathways” [Biochem. Pharmacol	21
Selective stabilization of the intermediate inactivated Na+ channel by the new-generation anticonvulsant rufinamide	21
The relevance of daylight for humans	21
3-Hydroxybutyrate ameliorates sepsis-associated acute lung injury by promoting autophagy through the activation of GPR109α in macrophages	21
Acknowledgment	21
Broad-spectrum hybrid antimicrobial peptides derived from PMAP-23 with potential LPS binding ability	21
Corrigendum to “Resveratrol inhibits epithelial-mesenchymal transition and renal fibrosis by antagonizing the hedgehog signaling pathway” [Biochem. Pharmacol. 92 (2014) 484–493]	21
Estrogen dampens central cannabinoid receptor 1-mediated neuroexcitation and pressor response in conscious female rats	21
Integrated metabolomics and transcriptomics reveal the neuroprotective effect of nervonic acid on LPS-induced AD model mice	21
AdipoRon and ADP355, adiponectin receptor agonists, in Metabolic-associated Fatty Liver Disease (MAFLD) and Nonalcoholic Steatohepatitis (NASH): A systematic review	21
Editorial Board	21
Heat shock protein 90 inhibitor 17-AAG down-regulates thymidine phosphorylase expression and potentiates the cytotoxic effect of tamoxifen and erlotinib in human lung squamous carcinoma cells	21
Targeting the JAK-STAT pathway in autoimmune diseases and cancers: A focus on molecular mechanisms and therapeutic potential	21
Detailed functional characterization of four nanobodies as positive allosteric modulators of the human calcium-sensing receptor	21
Luxeptinib disables NLRP3 inflammasome-mediated IL-1β release and pathways required for secretion of inflammatory cytokines IL-6 and TNFα	20
Curcumin protects against the age-related hearing loss by attenuating apoptosis and senescence via activating Nrf2 signaling in cochlear hair cells	20
A high affinity Sybody blocks Cofilin-1 binding to F-actin in vitro and in cancer cells	20
Pharmacological characterization of prostaglandin E2 EP2 and EP4 receptors in male rat locus coeruleus neurons ex vivo	20
Flavokawain B is an effective natural peroxisome proliferator-activated receptor γ-selective agonist with a strong glucose-lowering effect	20
AURKB and circAURKB_288aa enhance Esophageal cancer drug resistance through inducing abnormal centrosome separation	20
Bisphenol-A analogs induce lower urinary tract dysfunction in male mice	20
Activation of aryl hydrocarbon receptor by azatyrosine-phenylbutyric hydroxamide inhibits progression of diabetic retinopathy mice	20
Untargeted metabolomics analysis of serum and urine unveils the protective effect of cilastatin on altered metabolic pathways during cisplatin-induced acute kidney injury	20
Function and inhibition of DYRK1A: Emerging roles of treating multiple human diseases	20
Lysine β-hydroxybutyrylation promotes lipid accumulation in alcoholic liver disease	20
Vitamin B12 reversed anxiety and depression induced by adolescent nicotine withdrawal through alteration the inflammatory, oxidative and serotoninergic profiles in male rats	20
ITFG2 as a NEDD4-2 inhibitor: Preserving calcium homeostasis to prevent myocardial ischemic injury	20