Biology of Reproduction

Article	Citations
Sperm induce macrophage extracellular trap formation via phagocytosis-dependent mechanism	68
Purinergic system molecules: expression and regulation of enzymes, transporters, and adenosine triphosphate receptors and the role of adenosine triphosphate at the maternal–conceptus interface in pigs	56
Transcriptomic and histochemical analysis reveal the complex regulatory networks in equine chorioallantois during spontaneous term labor	45
Duplex sequencing identifies unique characteristics of ENU-induced mutations in male mouse germ cells	44
The potential effect of melatonin on in vitro oocyte maturation and embryo development in animals	44
Single cell multiome analysis of the bovine placenta identifies gene regulatory networks in trophoblast differentiation	43
Fetal hypoxia exposure induces Hif1a activation and autophagy in adult ovarian granulosa cells	40
AKAP3-mediated type I PKA signaling is required for mouse sperm hyperactivation and fertility	37
An interview with Dr. Gregory S. Kopf	37
C-X-C motif chemokine ligand 12 improves the developmental potential of bovine oocytes by activating SH2 domain-containing tyrosine phosphatase 2 during maturation	37
Conceptus interferon gamma is essential for establishment of pregnancy in the pig	37
Melatonin as a natural anti-inflammatory and anti-oxidant therapy in the testis: a focus on infertility and aging	35
Recognition of Billy Day for service to reproductive biologists	35
OoCount: A Machine-Learning Based Approach to Mouse Ovarian Follicle Counting and Classification	34
An interview with Dr Terry M. Nett	34
Advanced molecular approaches in male infertility diagnosis	29
Correction to: Activation of HAND2-FGFR signaling pathway by lncRNA HAND2-AS1 in adenomyosis	28
Biomarker-based human and animal sperm phenotyping: the good, the bad and the ugly	28
Aging and oxidative stress alter DNA repair mechanisms in male germ cells of superoxide dismutase-1 null mice	26
In Remembrance of a prolific reproductive biologist, editor of Biology of Reproduction, and enthusiastic supporter of young investigators	26
Estrogen to progesterone ratio is associated with conceptus attachment in dairy cows receiving artificial insemination after Double-Ovsynch but not estrus	25
CCDC189 depletion leads to oligo-astheno-teratozoospermia and male infertility in mice	25
In vitro maturation of oocytes: what is already known?	24
Expression patterns and the roles of phosphatidylinositol phosphatases in testis	24
Catalyzing momentum in male contraceptive development	24

The molecular chaperone cysteine string protein is required for monomeric SNARE proteins to assemble intrans-complexes during human sperm acrosomal exocytosis	23
Genetically engineered birds; pre-CRISPR and CRISPR era	23
Roles of the EF-hand domain of PLCZ1 in establishing species-specific Ca2+ oscillations in mouse and rat fertilization	21
The effects of bisphenol A and its analogs on steroidogenesis in MA-10 Leydig cells and KGN granulosa cells	21
Mechanistic target of rapamycin signaling activity in the human placenta across gestation and in maternal obesity	21
Preliminary urinary profiles of prolactin during gestation and the synergistic effects of embryonic diapause hormones in the giant panda (Ailuropoda melanoleuca)	21
Exposures during the prepuberty period and future offspring’s health: evidence from human cohort studies†	21
Digital analysis of ovarian tissue: generating a standardized method of follicle analysis	20
Loss of N-6 adenine-specific DNA methyltransferase 1 leads to meiotic prophase abnormalities and male sub-fertility in mice	20
Single-cell atlas of the pregnant equine endometrium before and after implantation	20
Guinea pig spermatozoa adhesion to an immobilized fibronectin matrix alters their physiology and increases their survival	19
Associations between isoflavone exposure and reproductive damage in adult males: evidence from human and model system studies	19
Phthalates and alternative plasticizers differentially affect phenotypic parameters in gonadal somatic and germ cell lines	19
Evidence of intergenerational transmission of diethylstilbestrol health effects: hindsight and insight	19
No evidence of the unfolded protein response in the placenta of two rodent models of preeclampsia and intrauterine growth restriction	18
Fertility and early embryonic development in a CD46-edited Gir heifer with reduced susceptibility to BVDV	18
Deletion of NFIX results in defective progression through meiosis within the mouse testis	18
CTNND1 affects trophoblast proliferation and specification during human embryo implantation	18
Exosomal ncRNAs in reproductive cancers	18
Transcriptome comparisons of trophoblasts from regenerative cell models with peri-implantation human embryos	18
Kisspeptin-54 injection induces a physiological luteinizing hormone surge and ovulation in mice	17
Biochemical markers for pregnancy in the spent culture medium of in vitro produced bovine embryos	17
Developmental programming: preconceptional and gestational exposure of sheep to biosolids on offspring ovarian dynamics	17
The alarmin S100A12 causes sterile inflammation of the human chorioamniotic membranes as well as preterm birth and neonatal mortality in mice	17
Sertoli cell replacement in explanted mouse testis tissue supporting host spermatogenesis†	17
Two-directional trafficking of the IFT25 protein in the developing mouse sperm flagella	17
Functional study of distinct domains of Dux in improving mouse SCNT embryonic development†	17
Modeling human peri-implantation placental development and function	17
Spermatogonial Dio3 as a potential germ line sensor for thyroid hormone-driven epigenetic inheritance	17
Role of autocrine bone morphogenetic protein signaling in trophoblast stem cells	16
Extracellular vesicle research in reproductive science: Paving the way for clinical achievements	16
Loss of basigin expression in uterine cells leads to subfertility in female mice	16
Kiss1 expression in the hypothalamic arcuate nucleus is lower in dairy cows of reduced fertility	16
ZDHHC19 localizes to the cell membrane of spermatids and is involved in spermatogenesis	16
MicroRNAs in amniotic fluid and maternal blood plasma associated with sex determination and early gonad differentiation in cattle	16
Evidence that pubertal status impacts kisspeptin/neurokinin B/dynorphin neurons in the gilt	16
Blocking the BKCa channel induces NF-κB nuclear translocation by increasing nuclear calcium concentration	16
Low CLOCK and CRY2 in 2nd trimester human maternal blood and risk of preterm birth: a nested case-control study†	16
Transgenerational effects of polychlorinated biphenyls: 2. Hypothalamic gene expression in rats	16
Varied effects of doxorubicin (DOX) on the corpus luteum of C57BL/6 mice during early pregnancy†	16
Inhibition of SHMT2 mRNA translation increases embryonic mortality in sheep	15
Advances in studying human gametogenesis and embryonic development in China	15
KIF3B gene silent variant leading to sperm morphology and motility defects and male infertility	15
MTOR-mediated interaction between the oocyte and granulosa cells regulates the development and function of both compartments in mice	15
Cervical immune activation during the luteal phase may compromise subsequent trans-cervical ram sperm transport	14
Research progress and application prospects of stable porcine pluripotent stem cells	14
Decreased junctional adhesion molecule 3 expression induces reactive oxygen species production and apoptosis in trophoblasts	14
Sertoli cells require TDP-43 to support spermatogenesis	13
Actin-related protein ACTL7B ablation leads to OAT with multiple morphological abnormalities of the flagellum and male infertility in mice	13
METTL3 promotes proliferation of goat endometrial epithelial cells by regulating CTGF in an m6A-dependent manner	13

A case of hermaphroditism in the gonochoristic sea urchin, Strongylocentrotus purpuratus, reveals key mechanisms of sex determination	13
Mitochondrial E3 ubiquitin ligase MARCH5 is required for mouse oocyte meiotic maturation	13
The combined impact of testosterone and Western-style diet on endometriosis severity and progression in rhesus macaques	13
Signal regulatory protein alpha is a conserved marker for mouse and rat spermatogonial stem cells	13
The transcriptomic response of bovine uterine tissue is altered in response to sperm from high- and low-fertility bulls	13
SOX8 is essential for male sexual differentiation in the Chinese soft-shelled turtle Pelodiscus sinensis	13
Loss of Raptor induces Sertoli cells into an undifferentiated state in mice	13
Aerobic exercises regulate the epididymal anion homeostasis of high-fat diet-induced obese rats through TRPA1-mediated Cl− and HCO3− secretion	13
Compensatory mechanisms in response to induced hypothyroidism in the late gestation pig fetus	13
Neurotensin expression, regulation, and function during the ovulatory period in the mouse ovary	13
Exercise enhances placental labyrinth trophoblast development by activation of PGC-1α and FNDC5/irisin	12
Circ_0115118 regulates endometrial functions through the miR-138-1-3p/WDFY2 axis in patients with PCOS	12
The fate of porcine sperm CRISP2 from the perinuclear theca before and after in vitro fertilization	12
Gestational intermittent hypoxia induces endothelial dysfunction and hypertension in pregnant rats: role of endothelin type B receptor	12
Novel progestogenic androgens for male contraception: design, synthesis, and activity of C7 α-substituted testosterone	12
Sperm selection by the oviduct: perspectives for male fertility and assisted reproductive technologies	12
Obesity partially potentiates dimethylbenz[a]anthracene-exposed ovotoxicity by altering the DNA damage repair response in mice	12
Melatonin-pretreated human umbilical cord mesenchymal stem cells improved endometrium regeneration and fertility recovery through macrophage immunomodulation in rats with intrauterine adhesions	12
CHD4 acts as a critical regulator in the survival of spermatogonial stem cells in mice	12
Haploid androgenetic development of bovine embryos reveals imbalanced WNT signaling and impaired cell fate differentiation	12
Segmental differentiation of the murine epididymis: identification of segment-specific, GM1-enriched vesicles and regulation by luminal fluid factors	11
The loss of dNK1/2 and EVT1 cells at the maternal–fetal interface is associated with recurrent miscarriage	11
Profiling of circulating extracellular vesicle microRNAs reveals diagnostic potential and pathways in non-obstructive and obstructive azoospermia	11
CTRP6 alleviates endometrial fibrosis by regulating Smad3 pathway in intrauterine adhesion	11
Design of novel oocyte activation methods: the role of zinc	11
Oxidative stress associated with proteomic and fatty acid profiles of sperm from Nellore bulls at rest	11
Reversible female contraceptives: historical, current, and future perspectives	11
Unveiling novel regulatory mechanisms of miR-5195-3p in pelvic organ prolapse pathogenesis	11
Cryptorchidism and testicular cancer in the dog: unresolved questions and challenges in translating insights from human studies	11
The pathogenesis of endometriosis and adenomyosis: insights from single-cell RNA sequencing	11
IL-32 regulates trophoblast invasion through miR-205-NFκB-MMP2/9 axis contributing to the pregnancy-induced hypertension	11
Overlapping peri-implantation phenotypes of ZNHIT1 and ZNHIT2 despite distinct functions during early mouse development	11
Targeted deletion of NR2F2 and VCAM1 in theca cells impacts ovarian follicular development: insights into polycystic ovary syndrome?	11
KDM6A/UTX promotes spermatogenic gene expression across generations and is not required for male fertility	11
Creatine metabolism at the uterine–placental interface throughout gestation in sheep	11
Physiological function of gut microbiota and metabolome on successful pregnancy and lactation in the captive Yangtze finless porpoise (Neophocaena asiaeorientalis asiaeorientalis)	11
4D label-free quantitative proteomic analysis identifies CRABP1 as a novel candidate gene for litter size in rabbits	11
Serum hydroxysteroid (17beta) dehydrogenase 1 concentration in pregnant women correlates with pregnancy-associated plasma protein A but does not serve as an independent marker for preeclampsia	11
Membrane inflammasome activation by choriodecidual Ureaplasma parvum infection without intra-amniotic infection in a Non-Human Primate model	11
Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice	11
Present state and future outlook for the application of in vitro oocyte maturation in human infertility treatment	10
Metabolomic markers of biological fluid in women with reproductive failure: a systematic review of current literatures	10
The fluid factor OVGP1 provides a significant oviductal microenvironment for the reproductive process in golden hamster	10
The roles of AKT isoforms in decidualization and embryo implantation using a PGR-Cre mouse model	10
Mettl3 downregulation in germinal vesicle oocytes inhibits mRNA decay and the first polar body extrusion during maturation	10
Activity of KNDy Neurons and the Melanocortin System During Pubertal Development in Female Sheep	10
Niclosamide’s potential direct targets in ovarian cancer	10
A critical appraisal of the circulating levels of differentially expressed microRNA in endometriosis	10
Metabolo-epigenetics: the interplay of metabolism and epigenetics during early germ cells development†	10
CK1α deficiency impairs mouse uterine adenogenesis by inducing epithelial cell apoptosis through GSK3β pathway and inhibiting Foxa2 expression through p53 pathway	10
Metabolic pathways of glucose and fructose: II Spatiotemporal expression of genes involved in synthesis and transport of lactate in ovine conceptuses	10
METTL14 mediates nerve growth factor-stimulated testosterone synthesis in porcine theca cells	10
Hypoxia-induced alteration of RNA modifications in the mouse testis and sperm	10
Long non-coding RNA NRSN2-AS1 facilitates tumorigenesis and progression of ovarian cancer via miR-744-5p/PRKX axis	10
Attenuated monoamine oxidase a impairs endometrial receptivity in women with adenomyosis via downregulation of FOXO1	10
Metabolic changes in female rats exposed to intrauterine hyperglycemia and postweaning consumption of high-fat diet	10
Endoplasmic reticulum stress: an emerging therapeutic target for preeclampsia	10
Loss of Nobox prevents ovarian differentiation from juvenile ovaries in zebrafish	10
Interleukin-10 and its receptors at the maternal–conceptus interface: expression, regulation, and implication for T helper 2 cytokine predominance and maternal immune tolerance in the pig, a true epit	10
An interview with Dr. Francesco J. DeMayo	9
Effects of the donor factors and freezing protocols on the bovine embryonic lipid profile	9
An interview with Dr. Vassilios Papadopoulos	9
Prenatal stress, anxiety and depression alter transcripts, proteins and pathways associated with immune responses at the maternal-fetal interface	9
An interview with Dr. Barry Zirkin	9
Hormonal profiles and biomarkers leading to parturition in cattle	9
Polystyrene micro- and nanoplastics cause placental dysfunction in mice	9
TGF-β1 induced activations of Smad2 and miRNAs inhibit SF-1- and LRH-1-dependent CYP19 expression in rat Leydig cells	9
Comparing the maternal-fetal microbiome of humans and cattle: a translational assessment of the reproductive, placental, and fetal gut microbiomes	9
Correction: Role of autocrine bone morphogenetic protein signaling in trophoblast stem cells	9
Acute and long-term transcriptomic responses of granulosa cells to obesogenic diet and concomitant effects on oocyte quality: insight from an outbred mouse model	9
Correction to: Sodium oligomannate’s amelioration of reproductive and metabolic phenotypes in a letrozole-induced PCOS-like mouse model depends on the gut microbiome	9
Proteomic determinants of uterine receptivity for pregnancy in early and mid-postpartum dairy cows	9
Correction to: The pathogenesis of endometriosis and adenomyosis: insights from single-cell RNA sequencing	9
The role of cholesterol/ALKBH1/ITGA2B in thrombosis in the placental vessels of preeclampsia	9
Age-associated changes in cumulus cells and follicular fluid: the local oocyte microenvironment as a determinant of gamete quality	9
Reactive oxygen and nitrogen species: multifaceted regulators of ovarian activity	9
Age-related integrative transcriptomic profiling of human granulosa cells reveals mRNA-microRNA regulatory network associated with key ovulation dynamics	9
How family histories can inform research about germ cell exposures: the example of autism	9
Correction to: YTHDF2 promotes DNA damage repair by positively regulating the histone methyltransferase SETDB1 in spermatogonia	9
Development of KISS1 knockout pigs is characterized by hypogonadotropic hypogonadism, normal growth, and reduced skatole	9

Conditional knockout of leptin receptor in the female reproductive tract reduces fertility due to parturition defects in mice	9
Primordial follicle activation: to be or not to be takes another twist	9
Genome activation in equine in vitro–produced embryos	9
SRA deficiency induces follicular dysplasia by disrupting the hypothalamic Kisspeptin-GPR54 system in mice	9
Microplastics are detected in bull epididymal sperm and polystyrene microparticles impair sperm fertilization	9
In Memorium of Professor Patricia B. Hoyer	9
LncRNA S100PBP promotes proliferation and steroid hormone synthesis of granulosa cells by sponging MiR-2285bc-BMPR2 in bovine	9
Low glucose and high pyruvate reduce the production of 2-oxoaldehydes, improving mitochondrial efficiency, redox regulation, and stallion sperm function†	8
The improvement of inflammatory infiltration and pregnancy outcome in mice with recurrent spontaneous abortion by human amniotic mesenchymal stem cells	8
Interaction of pre- and postnatal nutrition on expression of leptin receptor variants and transporter molecules, leptin transport, and functional response to leptin in heifers	8
Resveratrol improves follicular development in PCOS rats by inhibiting the inflammatory response and pyroptosis of granulosa cells	8
Correction to: The fluid factor OVGP1 provides a significant oviductal microenvironment for the reproductive process in golden hamster	8
AURKA inhibits the decidualization of the eutopic endometrium in endometriosis through nuclear factor-κB p65	8
Correction to: Roles of histone post-translational modifications in meiosis	8
Peri-estrus ovarian, uterine, and hormonal variables determine the uterine luminal fluid metabolome in beef heifers	8
METTL7A improves bovine IVF embryo competence by attenuating oxidative stress	8
Non-invasive oocyte quality assessment	8
Nobiletin-induced partial abrogation of deleterious effects of AKT inhibition on preimplantation bovine embryo development in vitro†	8
A memorial tribute to Dr. Koji Yoshinaga	8
SATINN v2: automated image analysis for mouse testis histology with multi-laboratory data integration	8
Aspects of human uterine creatine metabolism during the menstrual cycle and at term pregnancy	8
SHP2 regulates the HIF-1 signaling pathway in the decidual human endometrial stromal cells	8
Insight into the post-translational modifications in pregnancy and related complications	8
Ubiquitin-specific protease 7 prevents recurrent spontaneous abortion by targeting enhancer of zeste homolog 2 to regulate trophoblast proliferation, apoptosis, migration, and invasion through the Wnt	8
Sodium oligomannate’s amelioration of reproductive and metabolic phenotypes in a letrozole-induced PCOS-like mouse model depends on the gut microbiome	8
STAT3 in porcine endometrium during early pregnancy induces changes in extracellular matrix components and promotes angiogenesis	8
Corrigendum to: Abnormal early folliculogenesis due to impeded pyruvate metabolism in mouse oocytes†	8
Dnmt2-null sperm block maternal transmission of a paramutant phenotype†	8
Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice	8
Phosphatase and tensin homolog deficiency induces M2 macrophage polarization by promoting glycolytic activity in endometrial stromal cells	8
Mouse primary follicles experience slow growth rates after activation and progressive increases that influence the duration of the primary follicle phase	8
Anti-Müllerian hormone concentration measured before gonadotropin stimulation is associated with quality of subsequent ovarian response in the cheetah (Acinonyx jubatus) and domestic cat (Fe	8
Female fertility gets cilia(r) and cilia(r): ciliary defects in the oviduct compromises female fertility	8
Future of biomedical, agricultural, and biological systems research using domesticated animals	8
HOXA10 improves endometrial receptivity by upregulating E-cadherin	7
Delayed parenthood and its influence on offspring health: what have we learned from the mouse model	7
Germ cells: ENCODE’s forgotten cell type	7
Abnormal early folliculogenesis due to impeded pyruvate metabolism in mouse oocytes	7
RNF8 is not required for histone-to-protamine exchange in spermiogenesis	7
Blocking serine protease activity prevents semenogelin degradation leading to hyperviscous semen in humans	7
Morphogenesis of the female reproductive tract along antero-posterior and dorso-ventral axes is dependent on Amhr2+ mesenchyme in mice	7
Metabolic control of oocyte development	7
Environmental epigenetic interaction of gametes and early embryos	7
A decade of discovery: the stunning progress of premature ovarian insufficiency research in China	7
Aurora A Kinase (AURKA) is required for male germline maintenance and regulates sperm motility in the mouse.	7
Berberine alleviates LPS-induced apoptosis, oxidation, and skewed lineages during mouse preimplantation development	7
The molecular mechanisms underlying acrosome biogenesis elucidated by gene-manipulated mice†	7
Novel mineral regulatory pathways in ovine pregnancy: II. Calcium-binding proteins, calcium transporters, and vitamin D signaling	7
Vitrification preserves murine ovarian follicular cell transcriptome in a 3D encapsulatedin vitrofollicle growth system	7
Placental expression of estrogen-related receptor gamma is reduced in fetal growth restriction pregnancies and is mediated by hypoxia	7
Current understanding in deciphering trophoblast cell differentiation during human placentation	7
Noncanonical functions of PIWIL1/piRNAs in animal male germ cells and human diseases	7
The placenta as a target of opioid drugs	7
An evo-devo perspective of the female reproductive tract	7
Comparing mRNA and sncRNA profiles during the maternal-to-embryonic transition in bovine IVF and scNT embryos	7
The interleukin-6 trans-signaling promotes progesterone production in human granulosa-lutein cells	7
Preserving Oocytes in Oncofertility	7
PABPN1L assemble into “ring-like” aggregates in the cytoplasm of MII oocytes and is associated with female infertility†	7
Decreased B7-H3 promotes unexplained recurrent miscarriage via RhoA/ROCK2 signaling pathway and regulates the secretion of decidual NK cells	7
Responsible governance of human germline genome editing in China	7
The sodium-glucose cotransporter isoform 1 (SGLT-1) is important for sperm energetics, motility, and fertility	7
Effects of progesterone and interferon tau on ovine endometrial phosphate, calcium, and vitamin D signaling	7