OOIR: Observatory of International Research

Papers

(The H4-Index of Biotechnology and Bioengineering is 30. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Technology outlook for real‐time quality attribute and process parameter monitoring in biopharmaceutical development—A review	91
Scale‐up economics for cultured meat	88
Metabolic engineering of Pichia pastoris for malic acid production from methanol	63
The role of extracellular DNA in the formation, architecture, stability, and treatment of bacterial biofilms	62
Current technologies to endotoxin detection and removal for biopharmaceutical purification	59
“High‐risk” host cell proteins (HCPs): A multi‐company collaborative view	59
Advances in encapsulin nanocompartment biology and engineering	55
Biogenesis and mechanisms of microRNA‐mediated gene regulation	52
Hybrid‐EKF: Hybrid model coupled with extended Kalman filter for real‐time monitoring and control of mammalian cell culture	50
Improving lysine production through construction of an Escherichia coli enzyme‐constrained model	46
Consolidated bioprocessing performance of a two‐species microbial consortium for butanol production from lignocellulosic biomass	45
A review of manufacturing capabilities of cell spheroid generation technologies and future development	45
Overview on immobilization of enzymes on synthetic polymeric nanofibers fabricated by electrospinning	42
Ultrahigh‐cell‐density heterotrophic cultivation of the unicellular green alga Chlorella sorokiniana for biomass production	41
Moving from the bench towards a large scale, industrial platform process for adeno‐associated viral vector purification	40
A genome‐scale metabolic network model and machine learning predict amino acid concentrations in Chinese Hamster Ovary cell cultures	39
Optimizing the biosynthesis of oxygenated and acetylated Taxol precursors in Saccharomyces cerevisiae using advanced bioprocessing strategies	39
Advances in mapping the epigenetic modifications of 5‐methylcytosine (5mC), N6‐methyladenine (6mA), and N4‐methylcytosine (4mC)	38
A common framework for integrated and continuous biomanufacturing	36
Manufacturing a chimpanzee adenovirus‐vectored SARS‐CoV‐2 vaccine to meet global needs	36
A CRISPR‐Cas12a‐derived biosensor enabling portable personal glucose meter readout for quantitative detection of SARS‐CoV‐2	36
Production of β‐carotene in Saccharomyces cerevisiae through altering yeast lipid metabolism	34
Pilot‐scale demonstration of an end‐to‐end integrated and continuous biomanufacturing process	34
Rewiring central carbon metabolism for tyrosol and salidroside production in Saccharomyces cerevisiae	33
Bioprocess development for scalable production of cultivated meat	32

Extraction, isolation, purification, derivatization, bioactivity, structure–activity relationship, and application of polysaccharides from White jellyfungus	32
Modeling of photosynthesis and respiration rate for microalgae–bacteria consortia	32
End‐to‐end continuous bioprocessing: Impact on facility design, cost of goods, and cost of development for monoclonal antibodies	32
High‐level β‐carotene production from xylose by engineered Saccharomyces cerevisiae without overexpression of a truncated HMG1 (tHMG1)	31
Autofluorescence of blood and its application in biomedical and clinical research	31