OOIR: Observatory of International Research

Papers

(The H4-Index of Biotechnology and Bioengineering is 33. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
	79
Optical discrimination of pathological red blood cells	74
	65
	65
Computational fluid dynamics based digital twins of fixed bed bioreactors validate scaling principles for recombinant adeno‐associated virus gene therapy manufacturing	60
Biotechnology and Bioengineering: Volume 122, Number 12, December 2025	58
Effects of biofilm heterogeneity on the apparent mechanical properties obtained by shear rheometry	56
Dynamic D‐Allose Monitoring Via a Toggle‐Programmed Microbial Fluorescent Biosensor	54
Constructing multi‐enzymatic cascade reactions for selective production of 6‐bromoindirubin from tryptophan in Escherichia coli	53
An engineered ultrahigh affinity bi‐paratopic uPAR targeting agent confers enhanced tumor targeting	46
Concentration‐dependent diffusion of unlabeled protein within an in vitro hyaluronic acid matrix	44
Heterologous Expression of Candida antarctica Lipase B in Aspergillus niger Using CRISPR/Cas9‐mediated Multi‐Gene Editing	41
High‐throughput screening of optimal process conditions using model predictive control	40
Dual‐targeting multifunctional hyaluronic acid ligand‐capped gold nanorods with enhanced endo‐lysosomal escape ability for synergetic photodynamic–photothermal therapy of cancer	40
Dual‐Stage Cross‐Flow Filtration: Integrated Capture and Purification of Virus‐Like Particles	39
RSEA: A Web Server for Pathway Enrichment Analysis of Metabolic Reaction Sets	39
Double‐reporter‐guided targeted activation of the oxytetracycline silent gene cluster in Streptomyces rimosus M527	39
Phenazine‐Based Synthetic Biology to Signal Between Cells and Electrodes	39
Genetically Programmed Control of Overflow Metabolism	38
Engineering Plasmid‐Free Escherichia coli via Synergistic Metabolic Tuning and Fermentation Optimization for High‐Titer Salidroside Biosynthesis	38
Optimizing Pichia Pastoris Cell‐Free Protein Synthesis to Improve Economics	37
Repressing expression of difficult‐to‐express recombinant proteins during the selection process increases productivity of CHO stable pools	37
Recent Advances in Laccase‐Based Nanobiocatalysts for Sustainable Bioremediation Applications	37
Harnessing metabolic plasticity in CHO cells for enhanced perfusion cultivation	36
Engineered Stable, Antibiotic‐Free, High‐Level Protein Expression in the Probiotic Chassis Escherichia coli Nissle 1917	35

Elucidating the Interplay Between Resin Media, Feed Constituents, and Process Conditions in AAV Affinity Column Fouling With Confocal Microscopy	35
pH Threshold Impacts Chalcopyrite Bioleaching Dynamics for the Extreme Thermoacidophile Sulfurisphaera ohwakuensis	35
Super7 passaging method to improve Chinese hamster ovary cell fed‐batch performance	35
Current Advances and Future Prospects of Bulk and Microfluidic‐Enabled Electroporation Systems	34
Comparative Analysis of Bioreactor Design and Scale‐Up for Cultivated Meat Using Monte Carlo‐Based Timescale Modeling	34
Designing the MyoFusion Media: A Serum‐Free Medium Optimized for Bovine Satellite Cell Differentiation	33
Biotechnology and Bioengineering: Volume 122, Number 5, May 2025	33
Expression of filaments of the Geobacter extracellular cytochrome OmcS in Shewanella oneidensis	33
Iron in blood cells: Function, relation to disease, and potential for magnetic separation	33