OOIR: Observatory of International Research

Papers

(The H4-Index of Biotechnology and Bioengineering is 32. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Biotechnology and Bioengineering: Volume 122, Number 5, May 2025	135
Dual‐Stage Cross‐Flow Filtration: Integrated Capture and Purification of Virus‐Like Particles	59
Dual‐targeting multifunctional hyaluronic acid ligand‐capped gold nanorods with enhanced endo‐lysosomal escape ability for synergetic photodynamic–photothermal therapy of cancer	58
Double‐reporter‐guided targeted activation of the oxytetracycline silent gene cluster in Streptomyces rimosus M527	55
	55
Harnessing metabolic plasticity in CHO cells for enhanced perfusion cultivation	52
An engineered ultrahigh affinity bi‐paratopic uPAR targeting agent confers enhanced tumor targeting	49
	47
Super7 passaging method to improve Chinese hamster ovary cell fed‐batch performance	47
Optical discrimination of pathological red blood cells	47
	46
Continuous low pH viral inactivation: Operation and scaling strategy informs viral clearance study	46
RSEA: A Web Server for Pathway Enrichment Analysis of Metabolic Reaction Sets	46
pH Threshold Impacts Chalcopyrite Bioleaching Dynamics for the Extreme Thermoacidophile Sulfurisphaera ohwakuensis	45
Computational fluid dynamics based digital twins of fixed bed bioreactors validate scaling principles for recombinant adeno‐associated virus gene therapy manufacturing	43
Concentration‐dependent diffusion of unlabeled protein within an in vitro hyaluronic acid matrix	39
Iron in blood cells: Function, relation to disease, and potential for magnetic separation	38
Application and progress of 3D tumor models in breast cancer	38
Repressing expression of difficult‐to‐express recombinant proteins during the selection process increases productivity of CHO stable pools	37
Expression of filaments of the Geobacter extracellular cytochrome OmcS in Shewanella oneidensis	37
Biotechnology and Bioengineering: Volume 122, Number 12, December 2025	37
Elucidating the Interplay Between Resin Media, Feed Constituents, and Process Conditions in AAV Affinity Column Fouling With Confocal Microscopy	37
Concentration of clarified pool by single‐pass tangential flow filtration to improve productivity of protein A capture step: Impact of clarification strategies	36
High‐throughput screening of optimal process conditions using model predictive control	36
Enhanced bioprocess control to advance the manufacture of mesenchymal stromal cell‐derived extracellular vesicles in stirred‐tank bioreactors	35

Dynamic D‐Allose Monitoring Via a Toggle‐Programmed Microbial Fluorescent Biosensor	35
Effects of biofilm heterogeneity on the apparent mechanical properties obtained by shear rheometry	34
Application of gas diffusion electrodes in bioeconomy: An update	34
Constructing multi‐enzymatic cascade reactions for selective production of 6‐bromoindirubin from tryptophan in Escherichia coli	33
Engineered Stable, Antibiotic‐Free, High‐Level Protein Expression in the Probiotic Chassis Escherichia coli Nissle 1917	32
Current Advances and Future Prospects of Bulk and Microfluidic‐Enabled Electroporation Systems	32
Heterologous Expression of Candida antarctica Lipase B in Aspergillus niger Using CRISPR/Cas9‐mediated Multi‐Gene Editing	32