OOIR: Observatory of International Research

Papers

(The H4-Index of Biotechnology and Bioengineering is 31. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
	121
Super7 passaging method to improve Chinese hamster ovary cell fed‐batch performance	69
Optical discrimination of pathological red blood cells	53
An engineered ultrahigh affinity bi‐paratopic uPAR targeting agent confers enhanced tumor targeting	51
Back Cover Image, Volume 118, Number 11, November 2021	50
Double‐reporter‐guided targeted activation of the oxytetracycline silent gene cluster in Streptomyces rimosus M527	49
Continuous low pH viral inactivation: Operation and scaling strategy informs viral clearance study	49
Harnessing metabolic plasticity in CHO cells for enhanced perfusion cultivation	46
Effects of biofilm heterogeneity on the apparent mechanical properties obtained by shear rheometry	45
	45
Concentration of clarified pool by single‐pass tangential flow filtration to improve productivity of protein A capture step: Impact of clarification strategies	45
Expression of filaments of theGeobacterextracellular cytochrome OmcS inShewanella oneidensis	43
Evaluating potential of tissue‐engineered cryogels and chondrocyte derived exosomes in articular cartilage repair	43
Concentration‐dependent diffusion of unlabeled protein within an in vitro hyaluronic acid matrix	41
Computational fluid dynamics based digital twins of fixed bed bioreactors validate scaling principles for recombinant adeno‐associated virus gene therapy manufacturing	41
Constructing multi‐enzymatic cascade reactions for selective production of 6‐bromoindirubin from tryptophan in Escherichia coli	40
Application of gas diffusion electrodes in bioeconomy: An update	40
Leloir glycosyltransferases enabled to flow synthesis: Continuous production of the natural C‐glycoside nothofagin	40
pH Threshold Impacts Chalcopyrite Bioleaching Dynamics for the Extreme Thermoacidophile Sulfurisphaera ohwakuensis	40
Dual‐targeting multifunctional hyaluronic acid ligand‐capped gold nanorods with enhanced endo‐lysosomal escape ability for synergetic photodynamic–photothermal therapy of cancer	39
Repressing expression of difficult‐to‐express recombinant proteins during the selection process increases productivity of CHO stable pools	38
Enhanced bioprocess control to advance the manufacture of mesenchymal stromal cell‐derived extracellular vesicles in stirred‐tank bioreactors	35
	34
High‐throughput screening of optimal process conditions using model predictive control	34
Heterologous Expression of Candida antarctica Lipase B in Aspergillus niger Using CRISPR/Cas9‐mediated Multi‐Gene Editing	34

Application and progress of 3D tumor models in breast cancer	33
RSEA: A Web Server for Pathway Enrichment Analysis of Metabolic Reaction Sets	33
Current Advances and Future Prospects of Bulk and Microfluidic‐Enabled Electroporation Systems	33
Dual‐Stage Cross‐Flow Filtration: Integrated Capture and Purification of Virus‐Like Particles	33
Knowledge transfer across cell lines using hybrid Gaussian process models with entity embedding vectors	33
Iron in blood cells: Function, relation to disease, and potential for magnetic separation	33
Cover Image, Volume 118, Number 9, September 2021	31
Analyzing protein conjugation reactions for antibody‐drug conjugate synthesis using polarized excitation emission matrix spectroscopy	31
Biotechnology and Bioengineering: Volume 122, Number 5, May 2025	31
Continuous polyhydroxybutyrate production from biogas in an innovative two‐stage bioreactor configuration	31