OOIR: Observatory of International Research

Papers

(The H4-Index of Biotechnology and Bioengineering is 31. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
	157
Super7 passaging method to improve Chinese hamster ovary cell fed‐batch performance	107
	65
Optical discrimination of pathological red blood cells	62
An engineered ultrahigh affinity bi‐paratopic uPAR targeting agent confers enhanced tumor targeting	52
Leloir glycosyltransferases enabled to flow synthesis: Continuous production of the natural C‐glycoside nothofagin	48
Effects of biofilm heterogeneity on the apparent mechanical properties obtained by shear rheometry	48
Application and progress of 3D tumor models in breast cancer	47
Cover Image, Volume 118, Number 8, August 2021	46
Back Cover Image, Volume 118, Number 11, November 2021	46
Unlocking the structural features for the xylobiohydrolase activity of an unusual GH11 member identified in a compost‐derived consortium	43
Outside Back Cover Image, Volume 118, Number 7, July 2021	43
Constructing multi‐enzymatic cascade reactions for selective production of 6‐bromoindirubin from tryptophan in Escherichia coli	42
Harnessing metabolic plasticity in CHO cells for enhanced perfusion cultivation	41
Double‐reporter‐guided targeted activation of the oxytetracycline silent gene cluster in Streptomyces rimosus M527	41
Continuous low pH viral inactivation: Operation and scaling strategy informs viral clearance study	41
Heterologous Expression of Candida antarctica Lipase B in Aspergillus niger Using CRISPR/Cas9‐mediated Multi‐Gene Editing	39
Computational fluid dynamics based digital twins of fixed bed bioreactors validate scaling principles for recombinant adeno‐associated virus gene therapy manufacturing	39
Dual‐Stage Cross‐Flow Filtration: Integrated Capture and Purification of Virus‐Like Particles	39
Evaluating potential of tissue‐engineered cryogels and chondrocyte derived exosomes in articular cartilage repair	38
Concentration‐dependent diffusion of unlabeled protein within an in vitro hyaluronic acid matrix	37
Enhanced bioprocess control to advance the manufacture of mesenchymal stromal cell‐derived extracellular vesicles in stirred‐tank bioreactors	37
Concentration of clarified pool by single‐pass tangential flow filtration to improve productivity of protein A capture step: Impact of clarification strategies	37
pH Threshold Impacts Chalcopyrite Bioleaching Dynamics for the Extreme Thermoacidophile Sulfurisphaera ohwakuensis	35
Biotechnology and Bioengineering: Volume 122, Number 5, May 2025	35

Expression of filaments of theGeobacterextracellular cytochrome OmcS inShewanella oneidensis	33
RSEA: A Web Server for Pathway Enrichment Analysis of Metabolic Reaction Sets	32
High‐throughput screening of optimal process conditions using model predictive control	32
Dual‐targeting multifunctional hyaluronic acid ligand‐capped gold nanorods with enhanced endo‐lysosomal escape ability for synergetic photodynamic–photothermal therapy of cancer	32
Knowledge transfer across cell lines using hybrid Gaussian process models with entity embedding vectors	32
Application of gas diffusion electrodes in bioeconomy: An update	32
Repressing expression of difficult‐to‐express recombinant proteins during the selection process increases productivity of CHO stable pools	31
Iron in blood cells: Function, relation to disease, and potential for magnetic separation	31