Brain

Article	Citations
Correction to: Variants in the SK2 channel gene (KCNN2) lead to dominant neurodevelopmental movement disorders	396
Reply: Is postural tachycardia syndrome a psychogenic disorder?; Notes on establishing fear conditioning as causal in the postural orthostatic tachycardia syndrome; Patients with POTS fear that data o	391
Methodological drawbacks in the alleged association between foetal sonographic anomalies and autism	241
Clinical and genetic spectrum of 355 Chinese children with epilepsy: a trio-sequencing-based study	210
‘Seeding’ the idea of early diagnostics in synucleinopathies	209
PET-MRI biomarkers reveal efficacy of a novel NLRP3 inhibitor in Parkinson’s disease models	205
In vivo self-assembled siRNAs ameliorate neurological pathology in TDP-43-associated neurodegenerative disease	199
We’re all in this together: a rejoinder to Masud Husain’s (rant) editorial	192
Clinical and genetic characterization of a progressive RBL2-associated neurodevelopmental disorder	191
‘Hippocampal innate inflammatory gliosis only’ in pharmacoresistant temporal lobe epilepsy	190
Clinical dimensions along the non-fluent variant primary progressive aphasia spectrum	189
Impaired ribosome-associated quality control of C9orf72 arginine-rich dipeptide-repeat proteins	176
Deep brain stimulation: a tale of two targets … and closing the loop	172
The axon initial segment as a source of neuropathic pain	167
De novo variants in ATXN7L3 lead to developmental delay, hypotonia and distinctive facial features	153
Dysregulated cortical excitability and tau phosphorylation in a β3 integrin mouse model of autism	147
Lesion correlates of impaired acoustic-phonetic perception after unilateral left hemisphere stroke	147
Dysfunction of the magnocellular subdivision of the visual thalamus in developmental dyslexia	145
Mapping the peripheral immune landscape of Parkinson’s disease patients with single-cell sequencing	145
Global network and local vulnerabilities underlie brain atrophy across Parkinson’s disease stages	144
Choroid plexus mis-splicing and altered cerebrospinal fluid composition in myotonic dystrophy type 1	129
Thalamostriatal disconnection underpins long-term seizure freedom in frontal lobe epilepsy surgery	129
Biallelic ADAM22 pathogenic variants cause progressive encephalopathy and infantile-onset refractory epilepsy	128
Dopamine and the dynamics of subthalamic and leg muscle activities in parkinsonian stepping	127
Apathy, effort-based decisions and brain integrity in Alzheimer’s and Parkinson’s diseases	123

Associations between accelerated forgetting, amyloid deposition and brain atrophy in older adults	121
Optogenetic stimulation of the superior colliculus suppresses genetic absence seizures	119
Genetically identical twin-pair difference models support the amyloid cascade hypothesis	116
Trigeminal nerve microstructure is linked with neuroinflammation and brainstem activity in migraine	115
Somatic variants of MAP3K3 are sufficient to cause cerebral and spinal cord cavernous malformations	111
The inferior fronto-occipital fasciculus: bridging phylogeny, ontogeny and functional anatomy	111
Source-sink connectivity: a novel interictal EEG marker for seizure localization	110
ActivatingRAC1variants in the switch II region cause a developmental syndrome and alter neuronal morphology	106
The use of optical coherence tomography in neurology: a review	106
A data-driven study of Alzheimer's disease related amyloid and tau pathology progression	103
Gain-of-function and loss-of-function variants in GRIA3 lead to distinct neurodevelopmental phenotypes	102
Brain cholesterol and Alzheimer's disease: challenges and opportunities in probe and drug development	101
The vascular contribution of apolipoprotein E to Alzheimer’s disease	100
Peripherin is a biomarker of axonal damage in Guillain-Barré syndrome: a pathophysiological annotation	98
Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and cognitive decline	97
From bugs to brain: unravelling the GABA signalling networks in the brain–gut–microbiome axis	95
Speech and language markers of neurodegeneration: a call for global equity	94
Brain repair mechanisms after cell therapy for stroke	94
Correction to: New genotype-phenotype correlations in a large European cohort of patients with sarcoglycanopathy	94
Diffusion MRI tracks cortical microstructural changes during the early stages of Alzheimer’s disease	94
Molecular and clinical spectrum of epilepsy-dyskinesia syndromes: a cross-sectional study of 609 patients	93
Demystifying interictal discharges and seizure initiation in focal epilepsy	92
Reply: Unblinding in the lecanemab trial in Alzheimer’s disease	91
The spectrum of disease and tau pathology of nodding syndrome in Uganda	90
The three deceits of bureaucracy	89
Extra-cranial cholinergic lesions in dementia with Lewy bodies	87
Preclinical type 2 diabetes mellitus subtypes: new insights into diabetes, depression and dementia	86
New mechanistic insights into hereditary spastic paraplegias	86
Disruption of DNA methylation underpins the neuroinflammation induced by targeted CNS radiotherapy	84
Biallelic LGI1 and ADAM23 variants cause hippocampal epileptic encephalopathy via the LGI1–ADAM22/23 pathway	84
Normalization of network activity in an epilepsy model with a constitutively active GABBR2 variant	84
Treatment-resistant recurrent unipolar and bipolar depression: associative learning abnormalities	83
Functional network reorganization precedes apathy in Parkinson’s disease: a neural marker of risk?	82
How COVID-19 affects microvessels in the brain	82
Routes of precursors’ migration in remyelination	82
Multiple sclerosis in Denmark (1950–2023): mean age, sex distribution, incidence and prevalence	82
Multiple lines of evidence for disruption of nuclear lamina and nucleoporins in FUS amyotrophic lateral sclerosis	82
Evolutionary perspectives on mRNA signatures of neurodegeneration-related brain remodelling	81
Integrative miRNA–mRNA profiling of human epidermis: unique signature of SCN9A painful neuropathy	79
Natural experiment on neuroinflammatory disease incidence and infection links pre- and post-COVID-19	79
That which we call cortisol awakening response, by any other word would smell as sweet	78
Biallelic null variants in PNPLA8 cause microcephaly by reducing the number of basal radial glia	77
Cytotoxic T cells and plasma cells dominate early in temporal lobe epilepsy with GAD antibodies	76
Activation and sensitization of meningeal nociceptors by PACAP-38: implications for migraine headache	76
Genome-wide association study of neuropathological features in Lewy body disease	76
The interictal suppression hypothesis is the dominant differentiator of seizure onset zones in focal epilepsy	75
Is glymphatic clearance the secret to restorative sleep?	75
Stuttering associated with a pathogenic variant in the chaperone protein cyclophilin 40	72
Multimodal mapping of regional brain vulnerability to focal cortical dysplasia	72
Extracellular vesicle biomarkers for complement dysfunction in schizophrenia	71

A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings	71
The low dimensionality of post-stroke cognitive deficits: it’s the lesion anatomy!	69
Hippocampal synaptic failure is an early event in experimental parkinsonism with subtle cognitive deficit	69
Periventricular remyelination failure in multiple sclerosis: a substrate for neurodegeneration	69
Clinical and MRI measures to identify non-acute MOG-antibody disease in adults	68
Deciphering the impact of coding and non-coding SCN1A gene variants on RNA splicing	68
Defective lipid signalling caused by mutations inPIK3C2Bunderlies focal epilepsy	68
Integrative genomics reveals pathogenic mediator of valproate-induced neurodevelopmental disability	68
Structural covariance analysis for neurodegenerative and neuroinflammatory brain disorders	67
Multicentre analysis of seizure outcome predicted by removal of high-frequency oscillations	67
A sensory neuron-specific long non-coding RNA reduces neuropathic pain by rescuing KCNN1 expression	66
GGC repeat expansions in NOTCH2NLC cause uN2CpolyG cerebral amyloid angiopathy	66
Multifaceted nanoparticles: emerging mechanisms and therapies in neurodegenerative diseases	65
Clinical features and prognostic factors in adults with brain abscess	65
Long-term neuropsychological trajectories in children with epilepsy: does surgery halt decline?	64
Novel insight into TRPV1-induced mitochondrial dysfunction in neuropathic pain	64
Synaptic dysregulation in a mouse model of GRIN2D developmental and epileptic encephalopathy	64
Cross-seeding by prion protein inactivates TDP-43	64
Cortical cerebral microinfarcts spark cognitive decline	63
Loss of DOT1L disrupts neuronal transcription and leads to a neurodevelopmental disorder	63
From shadows to spotlight: the evolution of migraine stigma since the 17th century	62
Midbrain cytotoxic T cells as a distinct neuropathological feature of progressive supranuclear palsy	62
How modular are modules in visual cortex?	62
Neural stem cell therapies for spinal cord injury repair: an update on recent preclinical and clinical advances	62
Loss-of-function variants inMYCBP2cause neurobehavioural phenotypes and corpus callosum defects	62
Correction to: Sex-specific modulation of amyloid-β on tau phosphorylation underlies faster tangle accumulation in females	61
Correction to: Blood–brain barrier opening of the default mode network in Alzheimer's disease with magnetic resonance-guided focused ultrasound	61
Neural basis of speech and grammar symptoms in non-fluent variant primary progressive aphasia spectrum	60
Correction to: Remyelination of chronic demyelinated lesions with directly induced neural stem cells	60
Decoding inflammatory pathways in spinal muscular atrophy: implications for next-generation therapies	60
White matter connections within the central sulcus subserving the somato-cognitive action network	60
Correction to: Expanded clinical phenotype spectrum correlates with variant function in SCN2A-related disorders	59
Endosomal 2Cl−/H+ exchangers regulate neuronal excitability by tuning Kv7/KCNQ channel density	59
Widespread white matter oedema in subacute COVID-19 patients with neurological symptoms	59
A journey towards the pot of gold	58
Untangling white matter fibre changes in Alzheimer's disease and small vessel disease	58
Sorting out Parkinson’s disease: one cell at a time	58
UNC13B and focal epilepsy	57
Reply: The correlation of behavioural deficits post-stroke: a trivial issue?	57
Estimating the time course of biomarker changes in Alzheimer’s disease	57
Neuromelanin as a nidus for neurodegeneration	57
In silico versus functional characterization of genetic variants: lessons from muscle channelopathies	57
Reply: Lecanemab: turning point, or status quo? An ethics perspective	57
Reply: Do we need new MRI criteria for the diagnosis of radiologically isolated syndrome?	57
Occludin modulates HIV and ischaemic stroke response via mitochondrial antiviral signalling pathway	56
Repeat conformation heterogeneity in cerebellar ataxia, neuropathy, vestibular areflexia syndrome	56
Multicompartmental models and diffusion abnormalities in paediatric mild traumatic brain injury	56
Human lesions and animal studies link the claustrum to perception, salience, sleep and pain	55
Sleep and seizure risk in epilepsy: bed and wake times are more important than sleep duration	55
Startle responses in Duchenne muscular dystrophy: a novel biomarker of brain dystrophin deficiency	55
Imaging chronic active lesions in multiple sclerosis: a consensus statement	55
Cdc42GAP deficiency contributes to the Alzheimer’s disease phenotype	55
Basal forebrain integrity, cholinergic innervation and cognition in idiopathic Parkinson’s disease	55
The human subthalamic nucleus transiently inhibits active attentional processes	55
The lysosomal β-glucocerebrosidase strikes mitochondria: implications for Parkinson’s therapeutics	54
Age-related and amyloid-beta-independent tau deposition and its downstream effects	54
Anatomo-functional basis of emotional and motor resonance elicited by facial expressions	54
Effort avoidance as a core mechanism of apathy in frontotemporal dementia	54
Recovery from aphasia in the first year after stroke	54
Reduced striatal dopamine transmission as a transdiagnostic substrate of psychomotor retardation	53
Role of CD5 signalling for pro-inflammatory Th17 response in multiple sclerosis	53
Distinct cerebellar networks underpin clinical improvement in adolescent Tourette disorder	53
Amyloid-β predominant Alzheimer’s disease neuropathologic change	53
JC virus spread is potentiated by glial replication and demyelination-linked glial proliferation	53
A novel eye-movement impairment in multiple sclerosis indicating widespread cortical damage	53
Wheelchair use in genetically confirmed FSHD1 from a large cohort study in Chinese population	53
Impaired value-based decision-making in Parkinson’s disease apathy	52
Failure of C9orf72 sense repeat-targeting antisense oligonucleotides: lessons learned and the path forward	52
How patients with multiple sclerosis acquire disability	52
Early onset hereditary neuronopathies: an update on non-5qmotor neuron diseases	52
Nigrostriatal tau pathology in parkinsonism and Parkinson’s disease	52
Delineation of functionally essential protein regions for 242 neurodevelopmental genes	50
Genetic variability in sporadic amyotrophic lateral sclerosis	50
Motor neuron TDP-43 proteinopathy in progressive supranuclear palsy and corticobasal degeneration	50
Interferon-γ controls aquaporin 4-specific Th17 and B cells in neuromyelitis optica spectrum disorder	50
Large-scale rare variant burden testing in Parkinson's disease	50
Plasma VEGFA and PGF impact longitudinal tau and cognition in preclinical Alzheimer’s disease	50
Misdirected yet intact TREX1 exonuclease activity causes human cerebral and systemic small vessel disease	49
Bridging the gaps between JCV infection models and human disease	49
Common and distinct fronto-striatal volumetric changes in heroin and cocaine use disorders	49

Correction to: Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates	49
Is it time to rename hereditary cases of cerebral palsy?	49
Shedding light on a novel circuit within primary motor cortex as a target for neuromodulation	49
Cul-4 inhibition rescues spastin levels and reduces defects in hereditary spastic paraplegia models	48
Synaptic and cognitive impairment associated with L444P heterozygous glucocerebrosidase mutation	48
Surgical white matter disruption leads to downstream atrophy in the non-resected human brain	48
The visual cortex in the blind but not the auditory cortex in the deaf becomes multiple-demand regions	48
Thalamic stereo-EEG in epilepsy surgery: where do we stand?	47
Biomarker evidence of neurodegeneration in mid-life former rugby players	47
USP25 in genetic generalized epilepsy: a gene under scrutiny	47
Brain accumulation of lactosylceramide characterizes GALC deficiency in a zebrafish model of Krabbe disease	47
CGRP signalling in migraine: time to look downstream?	47
Amyloid-β-activated microglia can induce compound proteinopathies	47
A foothold in detection of limbic-predominant age-related TDP-43 encephalopathy	47
Anterior optic pathway pathology in CNS demyelinating diseases	47
Morc2a variants cause hydroxyl radical-mediated neuropathy and are rescued by restoring GHKL ATPase	47
Smarter adaptive platform clinical trials in neurology	47
Interleukin-17B is a new biomarker of human muscle regeneration in dystrophinopathies	47
Characterizing proteomic and transcriptomic features of missense variants in amyotrophic lateral sclerosis genes	47
Four dimensions of naturalistic language production in aphasia after stroke	46
Localizing epileptogenic tissues in epilepsy: are we losing (the) focus?	46
Motor network gamma oscillations in chronic home recordings predict dyskinesia in Parkinson’s disease	46
Ageing and remyelination failure in people with multiple sclerosis	46
Tiam1 is part of a novel mechanism for morphine tolerance and hyperalgesia	46
The ageing central nervous system in multiple sclerosis: the imaging perspective	46
Seeding, maturation and propagation of amyloid β-peptide aggregates in Alzheimer’s disease	46
Broad activation of the Parkin pathway induces synaptic mitochondrial deficits in early tauopathy	46
ZSCAN10 deficiency causes a neurodevelopmental disorder with characteristic oto-facial malformations	45
Cervical lymph nodes and ovarian teratomas as germinal centres in NMDA receptor-antibody encephalitis	45
Alzheimer proteopathic tau seeds are biochemically a forme fruste of mature paired helical filaments	45
C-terminal TMEM106B fragments in human brain correlate with disease-associated TMEM106B haplotypes	45
Understanding brain calcification via N-terminal acetylation at the Golgi apparatus	45
The basal forebrain cholinergic system as target for cell replacement therapy in Parkinson’s disease	45
PTPA variants and the risk for Parkinson’s disease in diverse ancestry populations	45
Interpretable surface-based detection of focal cortical dysplasias: a Multi-centre Epilepsy Lesion Detection study	45
Right temporal degeneration and socioemotional semantics: semantic behavioural variant frontotemporal dementia	45
Emotional bias modification weakens game-related compulsivity and reshapes frontostriatal pathways	45
Reply: The challenge of assessing invasive biomarkers for epilepsy surgery and To plan efficacious epilepsy surgery	44
Medial temporal lobe structural changes when Down syndrome and Alzheimer’s disease collide	44
Of networked lesions and lesioned networks	44
The functional role of the precuneus	44
Plasma biomarkers in chronic single moderate/severe traumatic brain injury	44
Motor compensation in Parkinson’s disease: an empirical challenge with clinical implications	44
Poor statistical reporting in a spinal cord injury clinical trial	43
One transgene, two myopathies: an MTM1 ‘cross gene therapy’ for BIN1 deficiency?	43
Ockham’s razor, not a barber’s weapon but a writer’s tool	43
Reply: Putative benefits of vitamin D supplements in multiple sclerosis out of reach due to sample size	43
Multimodal layer modelling reveals in vivo pathology in amyotrophic lateral sclerosis	43
Chasing MOG antibodies down … assays and lumbar punctures	43
Reply: Methodological drawbacks in the alleged association between foetal sonographic anomalies and autism	43
TGFβ4 alleviates the phenotype of Charcot–Marie–Tooth disease type 1A	43
Myelination potential and injury susceptibility of grey versus white matter human oligodendrocytes	42
Uncovering the distinct macro-scale anatomy of dysexecutive and behavioural degenerative diseases	42
Efficacy of MEDI0618, a pH-dependent monoclonal antibody targeting PAR2, in preclinical models of migraine	41
Brainstem cavernous malformations: observation, microsurgical resection or stereotactic radiosurgery	41
Great science does not communicate itself: but who should and how?	41
Reply: Neural substrates of the link between dual-task gait and dementia: an intermediary step in which direction?	41
Intra-putaminal muscarinic receptor agonist infusion induces a dystonic phenotype in non-human primates	41
Defining repetitive behaviours in frontotemporal dementia	41
An extended amygdala circuit at the core of long-term post-sepsis psychiatric disorders	41
Genome-wide epistasis analysis reveals significant epistatic signals associated with Parkinson’s disease risk	41
Reply: An epigenetic basis for genetic anticipation in facioscapulohumeral muscular dystrophy type 1	41
Ligand-free mitochondria-localized mutant AR-induced cytotoxicity in spinal bulbar muscular atrophy	41
Phenotypic individual clusters and metabolic tuber subtypes refine surgical strategy in tuberous sclerosis complex	40
Interaction of motor behaviour, cortical oscillations and deep brain stimulation in Parkinson’s disease	40
The importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis	40
Clinicopathological correlates in the frontotemporal lobar degeneration–motor neuron disease spectrum	40
Cerebellar pathology contributes to neurodevelopmental deficits in spinal muscular atrophy	40
Memory deficits of MDMA users are linked to cortical thinning related to 5-HT receptor densities	40
Connectivity as a universal predictor of tau progression in atypical Alzheimer’s disease	40
Spreading depolarizations in ischaemia after subarachnoid haemorrhage, a diagnostic phase III study	40
Phenoconversion in pure autonomic failure: a multicentre prospective longitudinal cohort study	39
Nifuroxazide rescues the deleterious effects due to CHCHD10-associated MICOS defects in disease models	39
Neurovascular injury with complement activation and inflammation in COVID-19	39
Limitation of life sustaining therapy in disorders of consciousness: ethics and practice	39
Direct electrical brain stimulation of human memory: lessons learnt and future perspectives	39
Mitochondrial damage is associated with an early immune response in inclusion body myositis	39
Motivational and cognitive predictors of apathy after subthalamic nucleus stimulation in Parkinson’s disease	39
Dynamic reorganization of task-related network interactions in post-stroke aphasia recovery	39
Mitochondrial dynamics and bioenergetics in Alzheimer’s induced pluripotent stem cell-derived neurons	39
Neurophysiological consequences of synapse loss in progressive supranuclear palsy	39
Heterozygous PRKN mutations are common but do not increase the risk of Parkinson’s disease	38
The Wernicke conundrum revisited: evidence from connectome-based lesion-symptom mapping	38
Genome-wide contribution of common short-tandem repeats to Parkinson’s disease genetic risk	38
Expedited epilepsy surgery prior to drug resistance in children: a frontier worth crossing?	38
Dopamine and deep brain stimulation accelerate the neural dynamics of volitional action in Parkinson's disease	38
Noradrenergic alterations in Parkinson’s disease: a combined 11C-yohimbine PET/neuromelanin MRI study	38
Increase of HCN current in SOD1-associated amyotrophic lateral sclerosis	38
Cation leak through the ATP1A3 pump causes spasticity and intellectual disability	38
Seronegative autoimmune encephalitis: clinical characteristics and factors associated with outcomes	38
Different factors underlie mild and severe forms of spinal muscular atrophy	37
Role of pattern recognition receptors in chemotherapy-induced neuropathic pain	37
Reply: Wheelchair use in genetically confirmed FSHD1 from a large cohort study in Chinese population	37
Clinical features and prognostic factors in adults with viral meningitis	37
Correction to: TMEM63C mutations cause mitochondrial morphology defects and underlie hereditary spastic paraplegia	37