Brain

Article	Citations
Erratum to: Cardiovascular brain impulses in Alzheimer’s disease	324
Peripherin is a biomarker of axonal damage in Guillain-Barré syndrome: a pathophysiological annotation	311
Corrigendum to: Defective phosphatidylethanolamine biosynthesis leads to a broad ataxia-spasticity spectrum	300
Redefining diagnostic lesional status in temporal lobe epilepsy with artificial intelligence	296
Erratum to: Reply: UQCRC1 variants in Parkinson’s disease: a large cohort study in Chinese mainland population	262
Dysregulation of muscle cholesterol transport in amyotrophic lateral sclerosis	259
Vessel size and clinical features in vasculitic neuropathy: dichotomy or continuum?	175
Clinical-grade intranasal NGF fuels neurological and metabolic functions of Mecp2-deficient mice	167
Raised intracranial pressure alters cortical vascular function and cephalic allodynia	157
Stereo-EEG propagating source reconstruction identifies new surgical targets for epilepsy patients	157
From bugs to brain: unravelling the GABA signalling networks in the brain–gut–microbiome axis	150
The inferior fronto-occipital fasciculus: bridging phylogeny, ontogeny and functional anatomy	148
CD21lo B cell subsets are recruited to the central nervous system in acute neuromyelitis optica	147
Fetal malformations of cortical development: review and clinical guidance	135
Distinctive clinical features in biopsy-proven nerve large-arteriole vasculitis and microvasculitis	135
Machine learning reveals connections between preclinical type 2 diabetes subtypes and brain health	134
Reply: Overstating harms can have consequences	130
‘Seeding’ the idea of early diagnostics in synucleinopathies	127
Corrigendum to: Comparative connectivity correlates of dystonic and essential tremor deep brain stimulation	127
Diffusion MRI tracks cortical microstructural changes during the early stages of Alzheimer’s disease	123
CNS manifestations in acute and chronic graft-versus-host disease	122
NPTX1 mutations trigger endoplasmic reticulum stress and cause autosomal dominant cerebellar ataxia	121
Speech and language markers of neurodegeneration: a call for global equity	121
Pre-symptomatic spinal muscular atrophy: a proposed nosology	118
Correction to: Variants in the SK2 channel gene (KCNN2) lead to dominant neurodevelopmental movement disorders	115

Navigating the recurrent perplexity of prefrontal function	115
Reducing the risks of nuclear war: the role of health professionals	115
Predicting behavioural outcomes after stroke: from computational challenge towards individualized rehabilitation?	113
Distinct neuroinflammatory signatures exist across genetic and sporadic amyotrophic lateral sclerosis cohorts	111
Venglustat combined with imiglucerase for neurological disease in adults with Gaucher disease type 3: the LEAP trial	110
Brain cholesterol and Alzheimer's disease: challenges and opportunities in probe and drug development	110
Age at onset of genetic disease and genetic dependent stage: evidence from cases with SCN1A variants	108
Recovered grasping performance after stroke depends on interhemispheric frontoparietal connectivity	103
Distinct roles of mTORC2 in excitatory and inhibitory neurons in inflammatory and neuropathic pain	103
Beyond crystal balls: multimodal prediction of early recovery of consciousness	103
The effect of Lewy body (co-)pathology on the clinical and imaging phenotype of amnestic patients	102
Notes on establishing fear conditioning as causal in the postural orthostatic tachycardia syndrome	102
Corrigendum to: Monitoring the progression of Alzheimer's disease with τ-PET	100
COP27 Climate Change Conference: urgent action needed for Africa and the world	99
Transcriptomic and connectomic correlates of differential spatial patterning among gliomas	98
Memantine: a novel treatment for children with developmental and epileptic encephalopathies	98
A CAG repeat threshold for therapeutics targeting somatic instability in Huntington's disease	96
Targeting enkephalins and pituitary adenylate cyclase-activating polypeptide (PACAP) in migraine	96
Hippocampal excitation-inhibition balance underlies the 5-HT2C receptor in modulating depressive behaviours	96
Correction to: Cytotoxic T cells and plasma cells dominate early in temporal lobe epilepsy with GAD antibodies	96
Cognitive flexibility, OCD and the brain	95
What plasma biomarkers tell us about hippocampal microstructural changes in Alzheimer’s disease	93
Correction to: Multimodal mapping of regional brain vulnerability to focal cortical dysplasia	86
Engram and ecphory: the performing pianist and retrieval of memory	86
A novel MLIP truncating variant in an 80-year-old patient with late-onset progressive weakness	85
Double vision	84
Time to treat the climate and nature crisis as one indivisible global health emergency	84
Correction to: Where have prions been all our lives?	83
Should concepts of brain functions be based on psychology or anatomy? An echo from Kurt Goldstein	83
Gain-of-function and loss-of-function variants in GRIA3 lead to distinct neurodevelopmental phenotypes	82
Magnetic resonance reveals mitochondrial dysfunction and muscle remodelling in spinal muscular atrophy	81
Mutation in senataxin alters the mechanism of R-loop resolution in amyotrophic lateral sclerosis 4	79
Preventing neurodegenerative disease	79
Serotonergic dysfunction impairs locomotor coordination in spinal muscular atrophy	77
RTN2 deficiency results in an autosomal recessive distal motor neuropathy with lower limb spasticity	76
Aquaporin-4 and GPRC5B: old and new players in controlling brain oedema	76
Spatiotemporal dynamics between interictal epileptiform discharges and ripples during associative memory processing	75
Erratum to: Complete sequencing of expanded SAMD12 repeats by long-read sequencing and Cas9-mediated enrichment	75
Somatosensory awareness in the parietal operculum	74
Ventromedial prefrontal cortex lesions disrupt learning to reward others	74
Clinical and genetic landscape of optic atrophy in 826 families: insights from 50 nuclear genes	74
Modulating inhibitory synaptic plasticity to restore basal ganglia dynamics in Parkinson’s disease	72
Trigeminal nerve microstructure is linked with neuroinflammation and brainstem activity in migraine	72
Distinct neuronal circuits mediate cortical hyperexcitability in amyotrophic lateral sclerosis	72
18F-MK-6240 tau-PET in genetic frontotemporal dementia	71
Neuropsychiatric disorders following SARS-CoV-2 infection	70
One step closer towards personalized epilepsy management	69
Assessment and prediction of glioblastoma therapy response: challenges and opportunities	69
Inhibiting mitochondrial fission rescues degeneration in hereditary spastic paraplegia neurons	69
Neurophysiological mechanisms of deep brain stimulation across spatiotemporal resolutions	68

Translating genetic and functional data into clinical practice: a series of 223 families with myotonia	68
Lesion correlates of impaired acoustic-phonetic perception after unilateral left hemisphere stroke	68
Lesions to both somatic and affective pain pathways lead to decreased salience network connectivity	67
The impact of integrated brain molecular PET measures on DLB cognitive phenotype and clinical course	67
Wittgenstein, neurology, and neuroscience	67
Running up that pill for amyotrophic lateral sclerosis	66
Impaired ribosome-associated quality control of C9orf72 arginine-rich dipeptide-repeat proteins	66
Glycolysis regulates neuronal excitability via lactate receptor, HCA1R	65
Using in vivo functional and structural connectivity to predict chronic stroke aphasia deficits	65
The etymology of ‘neurology’, redux: early use of the term by Jean Riolan the Younger (1610)	65
Reward insensitivity is associated with dopaminergic deficit in rapid eye movement sleep behaviour disorder	65
Cancer meets neuroscience: the association between glioma occurrence and intrinsic brain features	64
Thalamostriatal disconnection underpins long-term seizure freedom in frontal lobe epilepsy surgery	63
Complex genetic variants and novel phenotypes in hereditary peripheral neuropathies	63
Quantitative approaches to guide epilepsy surgery from intracranial EEG	63
Proust and his neurologists: the challenge of functional disorders	62
Brain microstructural and metabolic alterations detected in vivo at onset of the first demyelinating event	62
Choroid plexus mis-splicing and altered cerebrospinal fluid composition in myotonic dystrophy type 1	62
An in vivo Caenorhabditis elegans model for therapeutic research in human prion diseases	62
Where is the speech production area? Evidence from direct cortical electrical stimulation mapping	61
Genetic risk factor clustering within and across neurodegenerative diseases	61
From a different angle: 50 years of cerebral computed tomography	61
Functional protection in J20/VLW mice: a model of non-demented with Alzheimer’s disease neuropathology	61
Lesion location and lesion creation affect outcomes after focused ultrasound thalamotomy	61
New insights into the genetics of stuttering	60
Speak, memory: on cognitive reserve and brain resilience	59
Clinical dimensions along the non-fluent variant primary progressive aphasia spectrum	59
Erratum to: The Developing Human Connectome Project: typical and disrupted perinatal functional connectivity	59
Pathogenic mechanisms underlying SLC6A1 variant-mediated neurodevelopmental disorders	59
Predicting neurological recovery after traumatic spinal cord injury by time-resolved analysis of monocyte subsets	59
Blocking an epitope of misfolded SOD1 ameliorates disease phenotype in a model of amyotrophic lateral sclerosis	59
The multifaceted role of neurofilament light chain protein: emerging opportunities in primary psychiatric conditions	58
Expanding the mutational landscape and clinical phenotype of the YIF1B related brain disorder	58
Reversal of behavioural phenotype by the cannabinoid-like compound VSN16R in fragile X syndrome mice	58
Computational neuroscience: a grand unifying theory?	57
Sustained OMA1-mediated integrated stress response is beneficial for spastic ataxia type 5	57
Sleep and future cognitive decline	57
Clinical and genetic spectra of 1550 index patients with hereditary spastic paraplegia	56
Increased expression of SLC25A1/CIC causes an autistic-like phenotype with altered neuron morphology	56
Maf1 loss regulates spinogenesis and attenuates cognitive impairment in Alzheimer’s disease	55
The efficacy and deficiency of contemporary treatment for spinal cord arteriovenous shunts	55
Gut microbiome correlates with plasma lipids in amyotrophic lateral sclerosis	55
Normative brain mapping of interictal intracranial EEG to localize epileptogenic tissue	54
Early life predictors of late life cerebral small vessel disease in four prospective cohort studies	54
Sleep and longitudinal cognitive performance in preclinical and early symptomatic Alzheimer’s disease	54
c-Abl phosphorylation primes PARIS for neurodegeneration	53
Neuroinflammation is highest in areas of disease progression in semantic dementia	53
Impaired cholinergic integrity of the colon and pancreas in dementia with Lewy bodies	52
The axon initial segment as a source of neuropathic pain	52
Elevated cholesterol in ATAD3 mutants is a compensatory mechanism that leads to membrane cholesterol aggregation	52
A robust brain signature region approach for episodic memory performance in older adults	52
Anoctamin-5 related muscle disease: clinical and genetic findings in a large European cohort	52
Topographic divergence of atypical cortical asymmetry and atrophy patterns in temporal lobe epilepsy	52
Physick to Physiology	52
Neuropathic pain correlates with worsening cognition in people with human immunodeficiency virus	51
Deep brain stimulation: a tale of two targets … and closing the loop	51
Towards therapeutic non-invasive electrical modulation of brain circuits in Parkinson’s disease	50
Ataxia with giant axonopathy in Acbd5-deficient mice halted by adeno-associated virus gene therapy	50
Distinct subcellular autophagy impairments in induced neurons from patients with Huntington's disease	50
Nav1.2 channel mutations preventing fast inactivation lead to SCN2A encephalopathy	49
Quantitative susceptibility mapping at 7 T in COVID-19: brainstem effects and outcome associations	49
The effect of Huntington’s disease on cognitive and physical motivation	49
Reply: UNC13B and focal epilepsy	49
Reply: A call for caution: ‘stop that’ sentiments threaten tic research, healthcare and advocacy progress	49
Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI	48
Peripheral tau as a biomarker for neurodegenerative diseases: is life on Earth, life on Mars?	48
A cell autonomous regulator of neuronal excitability modulates tau in Alzheimer’s disease vulnerable neurons	48
Structural (dys)connectivity associates with cholinergic cell density in Alzheimer’s disease	48
Vitamin D did not reduce multiple sclerosis disease activity after a clinically isolated syndrome	48
A new type of blood–brain barrier aminoacidopathy underlies metabolic microcephaly associated with SLC1A4 mutations	47
Multi-ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke	47
When brain size matters: novel insights into brain volume control	47
Mapping interictal discharges using intracranial EEG-fMRI to predict postsurgical outcomes	47
SORD-deficient rats develop a motor-predominant peripheral neuropathy unveiling novel pathophysiological insights	47
Biallelic ADAM22 pathogenic variants cause progressive encephalopathy and infantile-onset refractory epilepsy	46
Enhancing cognitive performance prediction by white matter hyperintensity connectivity assessment	46
The anatomy of melancholy revisited after 400 years	46
De novo variants in ATXN7L3 lead to developmental delay, hypotonia and distinctive facial features	46
Clinical and genetic spectrum of 355 Chinese children with epilepsy: a trio-sequencing-based study	46
Functional variant rs2270363 on 16p13.3 confers schizophrenia risk by regulating NMRAL1	46

Clinical and genetic characterization of a progressive RBL2-associated neurodevelopmental disorder	45
A mutation in the PRKAR1B gene drives pathological mechanisms of neurodegeneration across species	45
A new Essay competition for Brain	45
ATP1A3 dysfunction causes motor hyperexcitability and afterhyperpolarization loss in a dystonia model	45
Late-onset temporal lobe epilepsy: insights from brain atrophy and Alzheimer’s disease biomarkers	45
Trigeminal microvascular decompression for short-lasting unilateral neuralgiform headache attacks	45
Low-intensity ultrasound ameliorates brain organoid integration and rescues microcephaly deficits	45
Astroglial reactivity is a key modulator of Alzheimer’s disease pathological progression	45
Forecasting stroke-like episodes and outcomes in mitochondrial disease	44
Dysfunction of the magnocellular subdivision of the visual thalamus in developmental dyslexia	44
The vascular contribution of apolipoprotein E to Alzheimer’s disease	44
Contribution of B cells to cortical damage in multiple sclerosis	44
Ash1l loss-of-function results in structural birth defects and altered cortical development	44
Endocannabinoid dysfunction in neurological disease: neuro-ocular DAGLA-related syndrome	44
Recurrent de novo mutations in CLDN5 induce an anion-selective blood–brain barrier and alternating hemiplegia	44
Aqp4 stop codon readthrough facilitates amyloid-β clearance from the brain	43
Grey matter ageing-related tau astrogliopathy: associations with brain pathologies and cognitive decline	43
Conserved patterns across ion channels correlate with variant pathogenicity and clinical phenotypes	43
Exploring the impact of somatic variant burden on seizures in focal cortical dysplasia	43
Reply: Is postural tachycardia syndrome a psychogenic disorder?; Notes on establishing fear conditioning as causal in the postural orthostatic tachycardia syndrome; Patients with POTS fear that data o	43
‘Hippocampal innate inflammatory gliosis only’ in pharmacoresistant temporal lobe epilepsy	43
Shared patterns of glial transcriptional dysregulation link Huntington’s disease and schizophrenia	42
Sex differences in Alzheimer’s disease risk: are immune responses the key?	42
Enhanced behavioural and neural sensitivity to punishments in chronic pain and fatigue	42
MNK1/2 contributes to periorbital hypersensitivity and hyperalgesic priming in preclinical migraine models	42
2023 Brain essay competition results	42
Age at onset mediates genetic impact on disease severity in facioscapulohumeral muscular dystrophy	42
Dopamine neuron dysfunction and loss in the PrknR275W mouse model of juvenile parkinsonism	42
Predictive precision medicine efforts for voltage-gated sodium channel genetic variants	42
Molecular pathology and biomarker of progression in Alzheimer’s disease	41
Le Bal des Folles	41
Deciphering the physiopathology of neurodevelopmental disorders using brain organoids	41
Methodological drawbacks in the alleged association between foetal sonographic anomalies and autism	41
Connecting dementia risk loci to the CSF proteome identifies pathophysiological leads for dementia	41
The expanding clinical and genetic spectrum of DYNC1H1-related disorders	41
Reply: Is it time to rename hereditary cases of cerebral palsy?	41
Proteomic clusters underlie heterogeneity in preclinical Alzheimer’s disease progression	40
Disruption of the blood–brain barrier in 22q11.2 deletion syndrome	40
TwoRFC1splicing variants in CANVAS	40
Location, location, location: myelin repair and proximity to ventricular CSF in multiple sclerosis	40
Lesion network mapping predicts post-stroke behavioural deficits and improves localization	40
Guillain-Barré syndrome, SARS-CoV-2 and molecular mimicry	40
Novel gene–intergenic fusion involving ubiquitin E3 ligase UBE3C causes distal hereditary motor neuropathy	40
Towards in vivo PET imaging of primary age-related tauopathy	40
Glucocorticoid-driven mitochondrial damage stimulates Tau pathology	40
The impact of phosphorylated PTEN at threonine 366 on cortical connectivity and behaviour	39
In-depth mass-spectrometry reveals phospho-RAB12 as a blood biomarker of G2019S LRRK2-driven Parkinson’s disease	39
Altered synaptic connectivity in anin vitrohuman model of STXBP1 encephalopathy	39
Droplet digital PCR as a first-tier molecular diagnostic tool for focal cortical dysplasia type II	39
Reply: Arcuate fasciculus’ middle and ventral temporal connections undercut by tract-tracing evidence	39
Exploring the link between dystrophic microglia and the spread of Alzheimer's neuropathology	39
The use of optical coherence tomography in neurology: a review	38
Unravelling the origin of reward positivity: a human intracranial event-related brain potential study	38
Dysregulation of protein SUMOylation networks in Huntington’s disease R6/2 mouse striatum	38
Shh activation restores interneurons and cognitive function in newborns with intraventricular haemorrhage	38
Inflammatory brain injury after severe viral infection is not unique to COVID-19	38
Parallel in-depth analysis of repeat expansions in ataxia patients by long-read sequencing	38
Distinct signatures of loss of consciousness in focal impaired awareness versus tonic-clonic seizures	38
CCL2 blockade combined with PD-1/P-selectin immunomodulators impedes breast cancer brain metastasis	38
Functional reconstruction of the basal ganglia neural circuit by human striatal neurons in hypoxic–ischaemic injured brain	38
Sensory axonal neuropathy in RFC1-disease: tip of the iceberg of broad subclinical multisystemic neurodegeneration	37
Correction to: INPP5K and SIL1 associated pathologies with overlapping clinical phenotypes converge through dysregulation of PHGDH	37
Synaptopathy: presynaptic convergence in frontotemporal dementia and amyotrophic lateral sclerosis	37
On-demand low-frequency stimulation for seizure control: efficacy and behavioural implications	37
Genetic landscape of congenital insensitivity to pain and hereditary sensory and autonomic neuropathies	37
Corrigendum to: UNC13B variants associated with partial epilepsy with favourable outcome	37
Novel modelling approaches to elucidate the genetic architecture of resilience to Alzheimer's disease	37
Somatic variants of MAP3K3 are sufficient to cause cerebral and spinal cord cavernous malformations	37
Neuronal intranuclear inclusion disease in patients with adult-onset non-vascular leukoencephalopathy	37
Are we entering the ‘Tau-lemaic’ era of Parkinson’s disease?	37
Temporal lobe epilepsy with GAD antibodies: neurons killed by T cells not by complement membrane attack complex	37
Correction to: Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis	37
Nuclear receptor PPARγ targets GPNMB to promote oligodendrocyte development and remyelination	37
Brain repair mechanisms after cell therapy for stroke	37
The most valuable player or the tombstone: is tau the correct target to treat Alzheimer’s disease?	37
Lymphotoxin-alpha expression in the meninges causes lymphoid tissue formation and neurodegeneration	37
Schizophrenia-associated changes in neuronal subpopulations in the human midbrain	36
Loss of the neuronal kinase DCLK3 leads to anxiety-like behaviour and memory deficits	36
Transthyretin attenuates TDP-43 proteinopathy by autophagy activation via ATF4 in FTLD-TDP	36
Methylation of the 4q35 D4Z4 repeat defines disease status in facioscapulohumeral muscular dystrophy	36
COVID-19 induces CNS cytokine expression and loss of hippocampal neurogenesis	35
A brain atlas of axonal and synaptic delays based on modelling of cortico-cortical evoked potentials	35
An epigenetic basis for genetic anticipation in facioscapulohumeral muscular dystrophy type 1	35
Post-acute blood biomarkers and disease progression in traumatic brain injury	35
Identification of biopsychological trait markers in functional neurological disorders	35
The multidimensional nature of aphasia recovery post-stroke	35
Blockage of STAT3 during epileptogenesis prevents GABAergic loss and imprinting of the epileptic state	35
CHCHD10 and SLP2 control the stability of the PHB complex: a key factor for motor neuron viability	35
Spectrum of sublytic astrocytopathy in neuromyelitis optica	35
3T MRI of rapid brain activity changes driven by subcallosal cingulate deep brain stimulation	35
Single unit analysis and wide-field imaging reveal alterations in excitatory and inhibitory neurons in glioma	35
Distinct brainstem to spinal cord noradrenergic pathways inversely regulate spinal neuronal activity	35
Homozygous COQ7 mutation: a new cause of potentially treatable distal hereditary motor neuropathy	34
Caspase cleavage of gasdermin E causes neuronal pyroptosis in HIV-associated neurocognitive disorder	34
Progression of clinical markers in prodromal Parkinson’s disease and dementia with Lewy bodies: a multicentre study	34