Brain

Article	Citations
Reply: Is postural tachycardia syndrome a psychogenic disorder?; Notes on establishing fear conditioning as causal in the postural orthostatic tachycardia syndrome; Patients with POTS fear that data o	355
The axon initial segment as a source of neuropathic pain	348
De novo variants in ATXN7L3 lead to developmental delay, hypotonia and distinctive facial features	305
Clinical dimensions along the non-fluent variant primary progressive aphasia spectrum	299
Impaired ribosome-associated quality control of C9orf72 arginine-rich dipeptide-repeat proteins	174
Thalamostriatal disconnection underpins long-term seizure freedom in frontal lobe epilepsy surgery	170
Correction to: Variants in the SK2 channel gene (KCNN2) lead to dominant neurodevelopmental movement disorders	170
Proust and his neurologists: the challenge of functional disorders	167
Methodological drawbacks in the alleged association between foetal sonographic anomalies and autism	167
Diffusion MRI tracks cortical microstructural changes during the early stages of Alzheimer’s disease	164
Brain repair mechanisms after cell therapy for stroke	156
Biallelic ADAM22 pathogenic variants cause progressive encephalopathy and infantile-onset refractory epilepsy	153
Clinical and genetic spectrum of 355 Chinese children with epilepsy: a trio-sequencing-based study	151
Optogenetic stimulation of the superior colliculus suppresses genetic absence seizures	145
Genetically identical twin-pair difference models support the amyloid cascade hypothesis	144
Dysregulated cortical excitability and tau phosphorylation in a β3 integrin mouse model of autism	143
Clinical and genetic characterization of a progressive RBL2-associated neurodevelopmental disorder	138
Deep brain stimulation: a tale of two targets … and closing the loop	134
Trigeminal nerve microstructure is linked with neuroinflammation and brainstem activity in migraine	132
From bugs to brain: unravelling the GABA signalling networks in the brain–gut–microbiome axis	128
The vascular contribution of apolipoprotein E to Alzheimer’s disease	128
Choroid plexus mis-splicing and altered cerebrospinal fluid composition in myotonic dystrophy type 1	128
Peripherin is a biomarker of axonal damage in Guillain-Barré syndrome: a pathophysiological annotation	127
We’re all in this together: a rejoinder to Masud Husain’s (rant) editorial	124
The use of optical coherence tomography in neurology: a review	122

Biallelic FRA10AC1 variants cause a neurodevelopmental disorder with growth retardation	121
Distinct subcellular autophagy impairments in induced neurons from patients with Huntington's disease	119
Brain cholesterol and Alzheimer's disease: challenges and opportunities in probe and drug development	116
Genetic evaluation of dementia with Lewy bodies implicates distinct disease subgroups	114
Associations between accelerated forgetting, amyloid deposition and brain atrophy in older adults	111
Gain-of-function and loss-of-function variants in GRIA3 lead to distinct neurodevelopmental phenotypes	111
Lesion correlates of impaired acoustic-phonetic perception after unilateral left hemisphere stroke	105
Imaging protein aggregates in the serum and cerebrospinal fluid in Parkinson’s disease	105
Source-sink connectivity: a novel interictal EEG marker for seizure localization	105
18F-MK-6240 tau-PET in genetic frontotemporal dementia	104
3T MRI of rapid brain activity changes driven by subcallosal cingulate deep brain stimulation	103
ActivatingRAC1variants in the switch II region cause a developmental syndrome and alter neuronal morphology	97
‘Seeding’ the idea of early diagnostics in synucleinopathies	96
Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and cognitive decline	93
Speech and language markers of neurodegeneration: a call for global equity	91
Dysfunction of the magnocellular subdivision of the visual thalamus in developmental dyslexia	89
Mapping the peripheral immune landscape of Parkinson’s disease patients with single-cell sequencing	88
‘Hippocampal innate inflammatory gliosis only’ in pharmacoresistant temporal lobe epilepsy	86
The inferior fronto-occipital fasciculus: bridging phylogeny, ontogeny and functional anatomy	85
Somatic variants of MAP3K3 are sufficient to cause cerebral and spinal cord cavernous malformations	84
A data-driven study of Alzheimer's disease related amyloid and tau pathology progression	84
Correction to: New genotype-phenotype correlations in a large European cohort of patients with sarcoglycanopathy	82
Synaptic dysregulation in a mouse model of GRIN2D developmental and epileptic encephalopathy	80
Multiple sclerosis in Denmark (1950–2023): mean age, sex distribution, incidence and prevalence	80
Hitching a ride on exosomes: a new approach for the delivery of siRNA-mediated therapies	80
Defective lipid signalling caused by mutations inPIK3C2Bunderlies focal epilepsy	79
Reply: Unblinding in the lecanemab trial in Alzheimer’s disease	79
Clinical features and prognostic factors in adults with brain abscess	78
Demystifying interictal discharges and seizure initiation in focal epilepsy	78
Genome-wide association study of neuropathological features in Lewy body disease	78
Clinically relevant mitochondrial-targeted therapy improves chronic outcomes after traumatic brain injury	78
Biallelic null variants in PNPLA8 cause microcephaly by reducing the number of basal radial glia	78
Hippocampal synaptic failure is an early event in experimental parkinsonism with subtle cognitive deficit	78
Intravenous delivery of adeno-associated viral gene therapy in feline GM1 gangliosidosis	77
Biallelic LGI1 and ADAM23 variants cause hippocampal epileptic encephalopathy via the LGI1–ADAM22/23 pathway	76
Multimodal mapping of regional brain vulnerability to focal cortical dysplasia	76
Evolutionary perspectives on mRNA signatures of neurodegeneration-related brain remodelling	75
Extra-cranial cholinergic lesions in dementia with Lewy bodies	75
The three deceits of bureaucracy	75
GGC repeat expansions in NOTCH2NLC cause uN2CpolyG cerebral amyloid angiopathy	74
New mechanistic insights into hereditary spastic paraplegias	74
Cytotoxic T cells and plasma cells dominate early in temporal lobe epilepsy with GAD antibodies	74
The low dimensionality of post-stroke cognitive deficits: it’s the lesion anatomy!	73
Functional network reorganization precedes apathy in Parkinson’s disease: a neural marker of risk?	73
BMP receptor blockade overcomes extrinsic inhibition of remyelination and restores neurovascular homeostasis	72
Preclinical type 2 diabetes mellitus subtypes: new insights into diabetes, depression and dementia	71
Stuttering associated with a pathogenic variant in the chaperone protein cyclophilin 40	71
A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings	70
Midbrain cytotoxic T cells as a distinct neuropathological feature of progressive supranuclear palsy	70
Clinical and MRI measures to identify non-acute MOG-antibody disease in adults	70

Loss of DOT1L disrupts neuronal transcription and leads to a neurodevelopmental disorder	70
Multiple lines of evidence for disruption of nuclear lamina and nucleoporins in FUS amyotrophic lateral sclerosis	70
Disruption of DNA methylation underpins the neuroinflammation induced by targeted CNS radiotherapy	70
How COVID-19 affects microvessels in the brain	69
Integrative miRNA–mRNA profiling of human epidermis: unique signature of SCN9A painful neuropathy	69
Structural covariance analysis for neurodegenerative and neuroinflammatory brain disorders	69
Multicentre analysis of seizure outcome predicted by removal of high-frequency oscillations	69
The neuroethics of disorders of consciousness: a brief history of evolving ideas	68
Integrative genomics reveals pathogenic mediator of valproate-induced neurodevelopmental disability	68
Novel insight into TRPV1-induced mitochondrial dysfunction in neuropathic pain	67
Cross-seeding by prion protein inactivates TDP-43	67
Deciphering the impact of coding and non-coding SCN1A gene variants on RNA splicing	67
Extracellular vesicle biomarkers for complement dysfunction in schizophrenia	65
The interictal suppression hypothesis is the dominant differentiator of seizure onset zones in focal epilepsy	65
A sensory neuron-specific long non-coding RNA reduces neuropathic pain by rescuing KCNN1 expression	63
Multifaceted nanoparticles: emerging mechanisms and therapies in neurodegenerative diseases	63
The spectrum of disease and tau pathology of nodding syndrome in Uganda	62
Long-term neuropsychological trajectories in children with epilepsy: does surgery halt decline?	62
Loss-of-function variants inMYCBP2cause neurobehavioural phenotypes and corpus callosum defects	62
Periventricular remyelination failure in multiple sclerosis: a substrate for neurodegeneration	61
Correction to: Blood–brain barrier opening of the default mode network in Alzheimer's disease with magnetic resonance-guided focused ultrasound	61
Neural stem cell therapies for spinal cord injury repair: an update on recent preclinical and clinical advances	61
The lysosomal β-glucocerebrosidase strikes mitochondria: implications for Parkinson’s therapeutics	60
Correction to: Sex-specific modulation of amyloid-β on tau phosphorylation underlies faster tangle accumulation in females	60
Failure of C9orf72 sense repeat-targeting antisense oligonucleotides: lessons learned and the path forward	60
Amyloid-β predominant Alzheimer’s disease neuropathologic change	59
Misdirected yet intact TREX1 exonuclease activity causes human cerebral and systemic small vessel disease	59
Repeat conformation heterogeneity in cerebellar ataxia, neuropathy, vestibular areflexia syndrome	58
Impaired value-based decision-making in Parkinson’s disease apathy	58
From shadows to spotlight: the evolution of migraine stigma since the 17th century	57
JC virus spread is potentiated by glial replication and demyelination-linked glial proliferation	57
How modular are modules in visual cortex?	57
Age-related and amyloid-beta-independent tau deposition and its downstream effects	57
Corrigendum to: Imaging protein aggregates in the serum and cerebrospinal fluid in Parkinson’s disease	57
Plasma VEGFA and PGF impact longitudinal tau and cognition in preclinical Alzheimer’s disease	57
A novel eye-movement impairment in multiple sclerosis indicating widespread cortical damage	56
Correction to: Expanded clinical phenotype spectrum correlates with variant function in SCN2A-related disorders	56
Untangling white matter fibre changes in Alzheimer's disease and small vessel disease	55
Sorting out Parkinson’s disease: one cell at a time	55
UNC13B and focal epilepsy	55
In silico versus functional characterization of genetic variants: lessons from muscle channelopathies	54
Reply: The correlation of behavioural deficits post-stroke: a trivial issue?	54
A journey towards the pot of gold	54
Delineation of functionally essential protein regions for 242 neurodevelopmental genes	54
Neuromelanin as a nidus for neurodegeneration	54
Reply: Do we need new MRI criteria for the diagnosis of radiologically isolated syndrome?	54
Reply: Lecanemab: turning point, or status quo? An ethics perspective	53
Random forest: random results or meaningful insights for patients with facioscapulohumeral muscular dystrophy?	53
Pallido-putaminal connectivity predicts outcomes of deep brain stimulation for cervical dystonia	53
Interferon-γ controls aquaporin 4-specific Th17 and B cells in neuromyelitis optica spectrum disorder	52
Multicompartmental models and diffusion abnormalities in paediatric mild traumatic brain injury	52
Wheelchair use in genetically confirmed FSHD1 from a large cohort study in Chinese population	52
White matter connections within the central sulcus subserving the somato-cognitive action network	51
Sleep and seizure risk in epilepsy: bed and wake times are more important than sleep duration	51
Common and distinct fronto-striatal volumetric changes in heroin and cocaine use disorders	51
Large-scale rare variant burden testing in Parkinson's disease	51
Motor neuron TDP-43 proteinopathy in progressive supranuclear palsy and corticobasal degeneration	50
Early onset hereditary neuronopathies: an update on non-5qmotor neuron diseases	50
Neural basis of speech and grammar symptoms in non-fluent variant primary progressive aphasia spectrum	50
Basal forebrain integrity, cholinergic innervation and cognition in idiopathic Parkinson’s disease	50
A passive and objective measure of recognition memory in Alzheimer’s disease using Fastball memory assessment	50
The human subthalamic nucleus transiently inhibits active attentional processes	50
How patients with multiple sclerosis acquire disability	49
Human lesions and animal studies link the claustrum to perception, salience, sleep and pain	49
Imaging chronic active lesions in multiple sclerosis: a consensus statement	49
Recovery from aphasia in the first year after stroke	49
Nigrostriatal tau pathology in parkinsonism and Parkinson’s disease	49
Intracranial pressure spikes trigger spreading depolarizations	49
Startle responses in Duchenne muscular dystrophy: a novel biomarker of brain dystrophin deficiency	48
Cdc42GAP deficiency contributes to the Alzheimer’s disease phenotype	48
Widespread white matter oedema in subacute COVID-19 patients with neurological symptoms	48
Effort avoidance as a core mechanism of apathy in frontotemporal dementia	48
Anatomo-functional basis of emotional and motor resonance elicited by facial expressions	48
Genetic variability in sporadic amyotrophic lateral sclerosis	48
Corrigendum to: Formation and immunomodulatory function of meningeal B cell aggregates in progressive CNS autoimmunity	47
CGRP signalling in migraine: time to look downstream?	47
Morc2a variants cause hydroxyl radical-mediated neuropathy and are rescued by restoring GHKL ATPase	47
PTPA variants and the risk for Parkinson’s disease in diverse ancestry populations	47
Characterizing proteomic and transcriptomic features of missense variants in amyotrophic lateral sclerosis genes	47
Motor compensation in Parkinson’s disease: an empirical challenge with clinical implications	46

Bridging the gaps between JCV infection models and human disease	46
Interleukin-17B is a new biomarker of human muscle regeneration in dystrophinopathies	46
Is it time to rename hereditary cases of cerebral palsy?	46
Brain accumulation of lactosylceramide characterizes GALC deficiency in a zebrafish model of Krabbe disease	46
Three-dimensional mapping of neurofibrillary tangle burden in the human medial temporal lobe	46
Erratum to: Reply: Broca’s area: why was neurosurgery neglected for so long when seeking to re-establish the scientific truth? and Where is the speech production area? Evidence from direct cort	46
Correction to: Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates	46
Understanding brain calcification via N-terminal acetylation at the Golgi apparatus	46
Emotional bias modification weakens game-related compulsivity and reshapes frontostriatal pathways	45
Diffusely abnormal white matter converts to T2 lesion volume in the absence of MRI-detectable acute inflammation	45
ZSCAN10 deficiency causes a neurodevelopmental disorder with characteristic oto-facial malformations	45
The visual cortex in the blind but not the auditory cortex in the deaf becomes multiple-demand regions	45
Imbalanced basal ganglia connectivity is associated with motor deficits and apathy in Huntington’s disease	45
Synaptic and cognitive impairment associated with L444P heterozygous glucocerebrosidase mutation	44
Shedding light on a novel circuit within primary motor cortex as a target for neuromodulation	44
Localizing epileptogenic tissues in epilepsy: are we losing (the) focus?	44
C-terminal TMEM106B fragments in human brain correlate with disease-associated TMEM106B haplotypes	43
Motor network gamma oscillations in chronic home recordings predict dyskinesia in Parkinson’s disease	43
Broad activation of the Parkin pathway induces synaptic mitochondrial deficits in early tauopathy	43
In vitro ictogenesis is stochastic at the single neuron level	43
Amyloid-β-activated microglia can induce compound proteinopathies	43
Cervical lymph nodes and ovarian teratomas as germinal centres in NMDA receptor-antibody encephalitis	43
Seeding, maturation and propagation of amyloid β-peptide aggregates in Alzheimer’s disease	42
Stimulation of frontal pathways disrupts hand muscle control during object manipulation	42
Interpretable surface-based detection of focal cortical dysplasias: a Multi-centre Epilepsy Lesion Detection study	42
Tiam1 is part of a novel mechanism for morphine tolerance and hyperalgesia	42
The basal forebrain cholinergic system as target for cell replacement therapy in Parkinson’s disease	42
Four dimensions of naturalistic language production in aphasia after stroke	42
Decomposing MRI phenotypic heterogeneity in epilepsy: a step towards personalized classification	41
Resting-state EEG reveals four subphenotypes of amyotrophic lateral sclerosis	41
Smarter adaptive platform clinical trials in neurology	41
Anterior optic pathway pathology in CNS demyelinating diseases	41
The functional role of the precuneus	41
Thalamic stereo-EEG in epilepsy surgery: where do we stand?	41
The ageing central nervous system in multiple sclerosis: the imaging perspective	41
Right temporal degeneration and socioemotional semantics: semantic behavioural variant frontotemporal dementia	40
Cul-4 inhibition rescues spastin levels and reduces defects in hereditary spastic paraplegia models	40
Poor statistical reporting in a spinal cord injury clinical trial	40
Reply: The challenge of assessing invasive biomarkers for epilepsy surgery and To plan efficacious epilepsy surgery	40
One transgene, two myopathies: an MTM1 ‘cross gene therapy’ for BIN1 deficiency?	40
Development of a novel tau propagation mouse model endogenously expressing 3 and 4 repeat tau isoforms	40
Corrigendum to: Myopathic mitochondrial DNA depletion syndrome associated with biallelic variants in LIG3	40
Reply: An epigenetic basis for genetic anticipation in facioscapulohumeral muscular dystrophy type 1	40
Chasing MOG antibodies down … assays and lumbar punctures	40
TGFβ4 alleviates the phenotype of Charcot–Marie–Tooth disease type 1A	40
Alzheimer proteopathic tau seeds are biochemically a forme fruste of mature paired helical filaments	40
Cation leak through the ATP1A3 pump causes spasticity and intellectual disability	40
The BS variant of C4 protects against age-related loss of white matter microstructural integrity	40
Reply: Methodological drawbacks in the alleged association between foetal sonographic anomalies and autism	40
Reply: Looking beyond indirect lesion network mapping of prosopagnosia: direct measures required	39
Reply: Putative benefits of vitamin D supplements in multiple sclerosis out of reach due to sample size	39
Plasma biomarkers in chronic single moderate/severe traumatic brain injury	39
Ockham’s razor, not a barber’s weapon but a writer’s tool	39
Of networked lesions and lesioned networks	39
Myelination potential and injury susceptibility of grey versus white matter human oligodendrocytes	38
Limitation of life sustaining therapy in disorders of consciousness: ethics and practice	38
Great science does not communicate itself: but who should and how?	38
Interaction of motor behaviour, cortical oscillations and deep brain stimulation in Parkinson’s disease	38
Genome-wide contribution of common short-tandem repeats to Parkinson’s disease genetic risk	38
An extended amygdala circuit at the core of long-term post-sepsis psychiatric disorders	38
Clinicopathological correlates in the frontotemporal lobar degeneration–motor neuron disease spectrum	38
Efficacy of MEDI0618, a pH-dependent monoclonal antibody targeting PAR2, in preclinical models of migraine	38
Nifuroxazide rescues the deleterious effects due to CHCHD10-associated MICOS defects in disease models	37
Neurovascular injury with complement activation and inflammation in COVID-19	37
Heterozygous PRKN mutations are common but do not increase the risk of Parkinson’s disease	37
Analysing an allelic series of rare missense variants of CACNA1I in a Swedish schizophrenia cohort	37
Expedited epilepsy surgery prior to drug resistance in children: a frontier worth crossing?	37
Genome-wide epistasis analysis reveals significant epistatic signals associated with Parkinson’s disease risk	37
Functional connectivity drives stroke recovery: shifting the paradigm from correlation to causation	37
Role of pattern recognition receptors in chemotherapy-induced neuropathic pain	37
Ligand-free mitochondria-localized mutant AR-induced cytotoxicity in spinal bulbar muscular atrophy	37
Mitochondrial damage is associated with an early immune response in inclusion body myositis	37
Medial temporal lobe structural changes when Down syndrome and Alzheimer’s disease collide	37
Uncovering the distinct macro-scale anatomy of dysexecutive and behavioural degenerative diseases	36
Mitochondrial dynamics and bioenergetics in Alzheimer’s induced pluripotent stem cell-derived neurons	36
Phenoconversion in pure autonomic failure: a multicentre prospective longitudinal cohort study	36
The Wernicke conundrum revisited: evidence from connectome-based lesion-symptom mapping	36
Dynamic reorganization of task-related network interactions in post-stroke aphasia recovery	36
Motivational and cognitive predictors of apathy after subthalamic nucleus stimulation in Parkinson’s disease	36
Seronegative autoimmune encephalitis: clinical characteristics and factors associated with outcomes	36
Increase of HCN current in SOD1-associated amyotrophic lateral sclerosis	36
Reply: Neural substrates of the link between dual-task gait and dementia: an intermediary step in which direction?	36
Defining repetitive behaviours in frontotemporal dementia	35
Multimodal layer modelling reveals in vivo pathology in amyotrophic lateral sclerosis	35
Dopamine and deep brain stimulation accelerate the neural dynamics of volitional action in Parkinson's disease	35
Brainstem cavernous malformations: observation, microsurgical resection or stereotactic radiosurgery	35
Noradrenergic alterations in Parkinson’s disease: a combined 11C-yohimbine PET/neuromelanin MRI study	35
Neurophysiological consequences of synapse loss in progressive supranuclear palsy	35
Predictors of functional outcomes in patients with facioscapulohumeral muscular dystrophy	35
The importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis	35
Direct electrical brain stimulation of human memory: lessons learnt and future perspectives	35
Spreading depolarizations in ischaemia after subarachnoid haemorrhage, a diagnostic phase III study	35
Clinical features and prognostic factors in adults with viral meningitis	35
Different factors underlie mild and severe forms of spinal muscular atrophy	34
On the complex localization and phenomenology of pathological laughter and crying	34