British Journal of Cancer

Papers
(The TQCC of British Journal of Cancer is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Advancing radiomics from contrast-enhanced mammography in breast cancer212
The EXO1/Polη/Polι axis as a promising target for miR-3163-mediated attenuation of cancer stem-like cells in non-small cell lung carcinoma164
Randomised, Phase II study of selumetinib, an oral inhibitor of MEK, in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer147
Genetic landscape of stage II melanoma identifies CBL as a new driver gene and prognostic biomarker140
Comprehensive assessment of actionable genomic alterations in primary colorectal carcinoma using targeted next-generation sequencing139
Hepatitis B virus X protein promotes MAN1B1 expression by enhancing stability of GRP78 via TRIM25 to facilitate hepatocarcinogenesis136
Metabolic adaptations in prostate cancer130
Proactive breast cancer risk assessment in primary care: a review based on the principles of screening124
Integrated genomic and transcriptomic analysis reveals the activation of PI3K signaling pathway in HPV-independent cervical cancers122
Correction To: Serplulimab, a novel anti-PD-1 antibody, in patients with microsatellite instability-high solid tumours: an open-label, single-arm, multicentre, phase II trial120
Correction: YY1 targets tubulin polymerisation-promoting protein to inhibit migration, invasion and angiogenesis in pancreatic cancer via p38/MAPK and PI3K/AKT pathways118
Correction: Wnt/ERK/CDK4/6 activation in the partial EMT state coordinates mammary cancer stemness with self-renewal and inhibition of differentiation114
Mutational spectrum of TP53 gene correlates with nivolumab treatment efficacy in advanced gastric cancer (TP53MUT study)108
Clinicopathological and molecular characteristics of RSPO fusion-positive colorectal cancer99
Hit it hard: qualitative patient perspectives on the optimisation of immune checkpoint inhibition99
Surveillance after childhood cancer: are survivors with an increased risk for cardiomyopathy regularly followed-up?95
Investigation of the gut microbiome, bile acid composition and host immunoinflammatory response in a model of azoxymethane-induced colon cancer at discrete timepoints94
Extranodal extension in lung adenocarcinoma: pathological insights and its implication as a histological marker of clinical aggressiveness93
Capecitabine combined with immunotherapy as maintenance therapy improves survival in recurrent/metastatic nasopharyngeal carcinoma: a retrospective cohort study92
Fibroblast activation protein-targeted near-infrared photoimmunotherapy depletes immunosuppressive cancer-associated fibroblasts and remodels local tumor immunity90
Years of life lost due to cancer in the United Kingdom from 1988 to 201787
Abemaciclib plus fulvestrant in treating hormone-receptor positive, HER2-negative advanced breast cancer—comparing real-world outcomes in England to the MONARCH-2 trial86
Breast cancer risk prediction with a modified BOADICEA model in Danish women86
Neoplasm risk in individuals with neurofibromatosis 1 – a Danish nationwide cohort study with long-term follow-up85
Diagnostic accuracy of combinatorial mRNA biomarkers for non-invasive detection and therapy monitoring of oral and oropharyngeal SCC83
Normal weight obesity, circulating biomarkers and risk of breast cancer: a prospective cohort study and meta-analysis83
Fibroblast growth factor signalling influences homologous recombination-mediated DNA damage repair to promote drug resistance in ovarian cancer82
Extruded small extracellular vesicles: splinters of circulating tumour cells may promote cancer metastasis?82
PANTHER: AZD8931, inhibitor of EGFR, ERBB2 and ERBB3 signalling, combined with FOLFIRI: a Phase I/II study to determine the importance of schedule and activity in colorectal cancer81
Correction to: Elevated APOBEC3B expression drives a kataegic-like mutation signature and replication stress-related therapeutic vulnerabilities in p53-defective cells78
Primary tumor sidedness and negative hyperselection to modulate anti-EGFR-based maintenance strategies in patients with RAS wild-type metastatic colorectal cancer: individual patient data pooled analy78
Efficacy of FOLFIRI plus cetuximab vs FOLFIRI plus bevacizumab in 1st-line treatment of older patients with RAS wild-type metastatic colorectal cancer: an analysis of the randomised trial FIRE-377
Mismatch repair markers in preoperative and operative endometrial cancer samples; expression concordance and prognostic value77
A very-hot food and beverage thermal exposure index and esophageal cancer risk in Malawi and Tanzania: findings from the ESCCAPE case–control studies76
Impact of clonal TP53 mutations with loss of heterozygosity on adjuvant chemotherapy and immunotherapy in gastric cancer73
Modulation of autophagy: a Phase II study of vorinostat plus hydroxychloroquine versus regorafenib in chemotherapy-refractory metastatic colorectal cancer (mCRC)72
Advances in cancer immunotherapy: adoptive cell therapy and immune cell engagers in solid tumours69
Assessments of social vulnerability on laryngeal cancer treatment & prognosis in the US68
Genomic ALK alterations in primary and relapsed neuroblastoma68
Metastasis-associated fibroblasts in peritoneal surface malignancies67
Identifying optimal first-line treatment for advanced non-small cell lung carcinoma with high PD-L1 expression: a matter of debate67
Targeting mitochondrial oxidative phosphorylation: lessons, advantages, and opportunities67
DRP1 inhibition-mediated mitochondrial elongation abolishes cancer stemness, enhances glutaminolysis, and drives ferroptosis in oral squamous cell carcinoma67
The prognostic and biology of tumour-infiltrating lymphocytes in the immunotherapy of cancer66
Identifying health conditions associated with an increased risk of pancreatic ductal adenocarcinoma at medium term in nationwide electronic health records of primary care physicians64
Somatic hits in mismatch repair genes in colorectal cancer among non-seminoma testicular cancer survivors63
Navigating therapeutic strategies: HPV classification in head and neck cancer63
Oxaliplatin induces pyroptosis in hepatoma cells and enhances antitumor immunity against hepatocellular carcinoma60
Prognostic relevance of the neurological symptom burden in brain metastases from breast cancer60
Editorial Expression of Concern: Decreased levels of baseline and drug-induced tubulin polymerisation are hallmarks of resistance to taxanes in ovarian cancer cells and are associated with epithelial-56
The HLA ligandome of oropharyngeal squamous cell carcinomas reveals shared tumour-exclusive peptides for semi-personalised vaccination56
Retraction Note: Toll-like receptor 9 agonist IMO cooperates with everolimus in renal cell carcinoma by interfering with tumour growth and angiogenesis56
Albendazole inhibits colon cancer progression and therapy resistance by targeting ubiquitin ligase RNF2056
Identification of increased dedifferentiation along the Prom1+ cancer cells in Müllerian adenosarcoma with sarcomatous overgrowth56
A comprehensive appraisal of HER2 heterogeneity in HER2-amplified and HER2-low colorectal cancer54
A Phase II study of neoadjuvant axitinib for reducing the extent of venous tumour thrombus in clear cell renal cell cancer with venous invasion (NAXIVA)52
Effect of risk-based screening for upper gastrointestinal cancers: a multi-center real-world study51
Evidence into practice: a national cohort study of NICE-recommended oncological drug therapy utilisation among women diagnosed with invasive breast cancer in England51
Nutritional status, body composition and chemotherapy dosing in children and young people with cancer: a systematic review by the SIOP nutrition network51
Phase 1 study of ceralasertib, an ATR kinase inhibitor, in combination with durvalumab in patients with recurrent or metastatic NSCLC or HNSCC50
The Glasgow Microenvironment Score and risk and site of recurrence in TNM I–III colorectal cancer49
Serum 25-hydroxyvitamin D concentrations and colorectal cancer incidence in adults with type 2 diabetes49
Contralateral breast cancer after radiotherapy and hormone therapy in two cohorts of US breast cancer survivors49
SLC7A11-AS1 contributes to prolonged activation of activin A/Smad signaling by suppressing PPM1A myristoylation in pancreatic cancer49
Relation knowledge distillation 3D-ResNet-based deep learning for breast cancer molecular subtypes prediction on ultrasound videos: a multicenter study49
Protein markers of ovarian cancer and its subtypes: insights from proteome-wide Mendelian randomisation analysis49
Risk of subsequent primary oral cancer in a cohort of 69,460 5-year survivors of childhood and adolescent cancer in Europe: the PanCareSurFup study48
Prognostic significance of PET/CT and its association with immuno-genomic profiling in oesophageal squamous cell carcinoma treated with immunotherapy plus chemoradiotherapy: results from a phase II st48
A Phase 1B open-label study of gedatolisib (PF-05212384) in combination with other anti-tumour agents for patients with advanced solid tumours and triple-negative breast cancer48
Optimizing adjuvant treatment strategies for non-pancreatic periampullary cancers48
The impact of the first 2 years of the COVID-19 pandemic on breast cancer diagnoses: a population-based study in England47
PTBP1 drives c-Myc-dependent gastric cancer progression and stemness46
Deep learning analysis of histopathological images predicts immunotherapy prognosis and reveals tumour microenvironment features in non-small cell lung cancer46
Tissue factor in cancer-associated thromboembolism: possible mechanisms and clinical applications45
Identification of MYCN non-amplified neuroblastoma subgroups points towards molecular signatures for precision prognosis and therapy stratification45
DNA repair-dependent immunogenic liabilities in colorectal cancer: opportunities from errors44
Clinical outcome and prognostic factors for Asian patients in Phase I clinical trials44
The SRC-family serves as a therapeutic target in triple negative breast cancer with acquired resistance to chemotherapy44
Neoadjuvant chemotherapy is noninferior to chemoradiotherapy for early-onset locally advanced rectal cancer in the FOWARC trial44
Long-term trends in incidence, characteristics and prognosis of screen-detected and interval cancers in women participating in the Dutch breast cancer screening programme44
Hypoxia- and Postirradiation reoxygenation-induced HMHA1/ARHGAP45 expression contributes to cancer cell invasion in a HIF-dependent manner44
Distant recurrence and margin involvement in invasive breast cancer44
Long-term use of antihypertensive medications, hypertension and colorectal cancer risk and mortality: a prospective cohort study42
eIF3i facilitates NELFCD translation to promote metastasis via regulating EMT and invadopodia42
Adolescent dietary patterns in relation to later prostate cancer risk and mortality in the NIH-AARP Diet and Health Study42
Cancer in Costello syndrome: a systematic review and meta-analysis42
Multistate models for the natural history of cancer progression42
EEF1A2 promotes HIF1A mediated breast cancer angiogenesis in normoxia and participates in a positive feedback loop with HIF1A in hypoxia42
Introduction and impact of routine whole genome sequencing in the diagnosis and management of sarcoma41
Emerging nanomedical strategies for direct targeting of pediatric and adult diffuse gliomas41
Clinical utility of BRCA and ATM mutation status in circulating tumour DNA for treatment selection in advanced pancreatic cancer41
Progress and priorities in reducing the time to cancer diagnosis41
Implications of obesity and insulin resistance for the treatment of oestrogen receptor-positive breast cancer41
Transcriptomic and functional analyses reveal a tumour-promoting role for the IL-36 receptor in colon cancer and crosstalk between IL-36 signalling and the IL-17/ IL-23 axis40
Mass spectrometric insights into the protein composition of human cutaneous neurofibromas: comparison of neurofibromas with the overlying skin40
A metabolomic analysis of adiposity measures and pre- and postmenopausal breast cancer risk in the Nurses’ Health Studies40
The in vitro dynamics of pseudo-vascular network formation40
Pathological complete response, category change, and prognostic significance of HER2-low breast cancer receiving neoadjuvant treatment: a multicenter analysis of 2489 cases39
Sequential targeting of PARP with carboplatin inhibits primary tumour growth and distant metastasis in triple-negative breast cancer39
A Phase Ib/II study of IGF-neutralising antibody xentuzumab with enzalutamide in metastatic castration-resistant prostate cancer39
Alkaline phosphatase decline and pain response as predictors of overall survival benefit in patients treated with radium-223: a post hoc analysis of the REASSURE study39
Routes to diagnosis for hepatocellular carcinoma patients: predictors and associations with treatment and mortality39
Correction: Targeting oncogenic microRNAs from the miR-371~373 and miR-302/367 clusters in malignant germ cell tumours causes growth inhibition through cell cycle disruption38
Safety, tolerability, and pharmacokinetics of Aurora kinase B inhibitor AZD2811: a phase 1 dose-finding study in patients with advanced solid tumours38
Correction to: Methyl-CpG-binding domain 3 inhibits epithelial–mesenchymal transition in pancreatic cancer cells via TGF-β/Smad signalling38
Correction: Modelled mortality benefits of multi-cancer early detection screening in England38
The mediating role of combined lifestyle factors on the relationship between education and gastric cancer in the Stomach cancer Pooling (StoP) Project38
Correction: Differential cellular origins of the extracellular matrix of tumor and normal tissues according to colorectal cancer subtypes38
Correction: Menopausal hormone therapy and breast cancer risk: a population-based cohort study of 1.3 million women in Norway38
Confidence bands in survival analysis38
Capturing breast cancers’ copy-number landscape in routine pathology: Exploiting low-resolution, genome-wide sequencing to identify HRD and beyond37
Exploiting dietary fibre and the gut microbiota in pelvic radiotherapy patients37
High-throughput precision MRI assessment with integrated stack-ensemble deep learning can enhance the preoperative prediction of prostate cancer Gleason grade37
Germline BRCA1/2 status and chemotherapy response score in high-grade serous ovarian cancer37
The prognostic impact of peritoneal tumour DNA in gastrointestinal and gynaecological malignancies: a systematic review37
The prognostic value of MEK pathway–associated estrogen receptor signaling activity for female cancers37
Cancer risk in individuals with polydactyly: a Swedish population-based cohort study37
Manassantin A inhibits tumour growth under hypoxia through the activation of chaperone-mediated autophagy by modulating Hsp90 activity37
Novel prognostic implications of complement activation in the tumour microenvironment for de novo metastatic BRAF V600E mutant colorectal cancer37
MET exon 14 skipping mutation drives cancer progression and recurrence via activation of SMAD2 signalling37
Clinical efficacy and immune response of neoadjuvant camrelizumab plus chemotherapy in resectable locally advanced oesophageal squamous cell carcinoma: a phase 2 trial35
Efficacy and quality of life for FOLFOX/bevacizumab +/− irinotecan in first-line metastatic colorectal cancer—final results of the AIO CHARTA trial35
Extending the dosing intervals of nivolumab: model-based simulations in unselected cancer patients35
Benchmarking standard-of-care and emerging genomic approaches to enhance diagnosis in pediatric acute lymphoblastic leukemia34
A UK prospective multicentre decision impact, decision conflict and economic evaluation of the 21-gene assay in women with node+ve, hormone receptor+ve, HER2-ve breast cancer34
Cannabinoids induce cell death in leukaemic cells through Parthanatos and PARP-related metabolic disruptions34
A multimodal imaging study to highlight elastin-derived peptide pro-tumoral effect in a pancreatic xenograft model34
Modelled impact of a multi-cancer early detection screening programme on cancer treatment in England33
Measurable residual disease analysis in paediatric acute lymphoblastic leukaemia patients with ABL-class fusions33
Characterisation of FLT3 alterations in childhood acute lymphoblastic leukaemia33
Thinking inside the box: intracellular roles for complement system proteins come into focus33
Immune evasion in lung metastasis of leiomyosarcoma: upregulation of EPCAM inhibits CD8+ T cell infiltration33
UK Biobank: a globally important resource for cancer research33
Integrated proteomics and scRNA-seq analyses of ovarian cancer reveal molecular subtype-associated cell landscapes and immunotherapy targets33
Cost-effectiveness of one-off upper abdominal CT screening as an add-on to lung cancer screening in England33
Immune checkpoint inhibitor combinations—current and emerging strategies32
Investigating PAK inhibition in combination with PD-1 blockade to enhance cytotoxic CD8+ T cell-mediated killing and suppress invasion of ovarian cancer cells32
Deciphering the central role of TMOD2 in colorectal cancer progression and metastasis32
50 years on and still very much alive: ‘Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics’32
Molecular response assessment using circulating tumor DNA (ctDNA) in advanced solid tumors31
Hyperglycaemia induces metabolic reprogramming into a glycolytic phenotype and promotes epithelial-mesenchymal transitions via YAP/TAZ-Hedgehog signalling axis in pancreatic cancer31
Postdiagnosis physical activity is associated with improved survival in prostate cancer patients treated with surgery but not with radiation therapy31
Chromatin accessibility uncovers KRAS-driven FOSL2 promoting pancreatic ductal adenocarcinoma progression through up-regulation of CCL2831
Identification of diagnostic biomarkers in prostate cancer-related fatigue by construction of predictive models and experimental validation31
What do women think about having received their breast cancer risk as part of a risk-stratified NHS Breast Screening Programme? A qualitative study31
Population-based nasopharyngeal carcinoma survival in southern China31
Oesophageal cancer awareness and anticipated time to help-seeking: results from a population-based survey31
Reply to Dr. Rafael Rosell: Shedding some light on the unresolved issue of YAP1 Ser397 phosphorylation in cancer31
Recurrent somatic mutations of FAT family cadherins induce an aggressive phenotype and poor prognosis in anaplastic large cell lymphoma30
Transient centrosome loss in cultured prostate epithelial cells induces chromosomal instability to produce an oncogenic genotype that correlates with poor clinical outcomes30
Exosomal transfer of miR-181b-5p confers senescence-mediated doxorubicin resistance via modulating BCLAF1 in breast cancer30
Plasma extracellular vesicle circRNA signature and resistance to abiraterone in metastatic castration-resistant prostate cancer30
Effects of preoperative recombinant Interleukin 2-based immunomodulation on outcome after gastrointestinal cancer surgery: a systematic review and meta-analysis30
The role of genetic predisposition in cardiovascular risk after cancer diagnosis: a matched cohort study of the UK Biobank30
HECTD3 regulates the tumourigenesis of glioblastoma by polyubiquitinating PARP1 and activating EGFR signalling pathway30
Stroma AReactive Invasion Front Areas (SARIFA) and the tumour immune microenvironment in colorectal cancer30
Breast cancer cell-derived adrenomedullin confers cancer-associated adipose remodeling through the cAMP/Creb1/Zeb1 axis29
Correction to: The Cancer Research UK Stratified Medicine Programme as a model for delivering personalised cancer care29
Health benefits and harms of mammography screening in older women (75+ years)—a systematic review29
Nonrandomised controlled trial in recurrent glioblastoma patients: the promise of autologous tumour lysate-loaded dendritic cell vaccination29
Sodium nitrite orchestrates macrophage mimicry of tongue squamous carcinoma cells to drive lymphatic metastasis29
Correction: Chromatin profile-based identification of a novel ER-positive breast cancer subgroup with reduced ER-responsive element accessibility29
EIF4A3-negatively driven circular RNA β-catenin (circβ-catenin) promotes colorectal cancer progression via miR-197-3p/CTNND1 regulatory axis28
Targeting the DNA damage response prevents regrowth of colorectal peritoneal metastasis-derived organoids following treatment with mitomycin C28
Imipridones inhibit tumor growth and improve survival in an orthotopic liver metastasis mouse model of human uveal melanoma28
Survival outcomes of ERBB2-amplified metastatic colorectal cancer treated with first-line chemotherapy28
Overall survival with maintenance olaparib in platinum-sensitive relapsed ovarian cancer by somatic or germline BRCA and homologous recombination repair mutation status28
Preferences for multi-cancer tests (MCTs) in primary care: discrete choice experiments of general practitioners and the general public in England28
Sorafenib plus selective internal radiotherapy with 90Y resin microspheres for the treatment of uveal melanoma with liver metastasis: a phase I trial28
Regulatory non-coding somatic mutations as drivers of neuroblastoma28
Impact of the selective A2AR and A2BR dual antagonist AB928/etrumadenant on CAR T cell function27
Galectin-9-driven immunosuppressive macrophage population shapes the lymph node metastatic microenvironment27
Impact of obesity on chemotherapy dosing of carboplatin and survival of women with ovarian cancer27
Resectability, conversion, metastasectomy and outcome according to RAS and BRAF status for metastatic colorectal cancer in the prospective RAXO study27
DNA ploidy and PTEN as biomarkers for predicting aggressive disease in prostate cancer patients under active surveillance27
Repositioning canakinumab for non-small cell lung cancer—important lessons for drug repurposing in oncology27
COLUMBIA-1: a randomised study of durvalumab plus oleclumab in combination with chemotherapy and bevacizumab in metastatic microsatellite-stable colorectal cancer27
Cancer-associated fibroblasts expressing fibroblast activation protein and podoplanin in non-small cell lung cancer predict poor clinical outcome27
Targeting oncogenic microRNAs from the miR-371~373 and miR-302/367 clusters in malignant germ cell tumours causes growth inhibition through cell cycle disruption27
Reasons for non-feasibility of therapeutic drug monitoring of oral targeted therapies in oncology – an analysis of the closed cohorts of a multicentre prospective study27
Prognostic significance of pathogenic variants in BRCA1, BRCA2, ATM and PALB2 genes in men undergoing hormonal therapy for advanced prostate cancer27
Boron neutron capture therapy (BNCT) for experimental bladder cancer: systemic or intravesical approach27
Patient-centered outcomes according to cancer status in cardiac surgery patients: a population-based cohort study27
Single-cell sequencing of PIT1-positive pituitary adenoma highlights the pro-tumour microenvironment mediated by IFN-γ-induced tumour-associated fibroblasts remodelling27
The National COVID Cancer Antibody Survey: a hyper-accelerated study proof of principle for cancer research27
Comprehensive multiplexed immune profiling of the ductal carcinoma in situ immune microenvironment regarding subsequent ipsilateral invasive breast cancer risk27
Outcomes of patients with HER2-negative metastatic breast cancer after platinum- and non-platinum-based first-line chemotherapy among patients with and without pathogenic germline BRCA1/2 mutations27
Trifluridine/tipiracil+bevacizumab (BEV) vs. fluoropyrimidine-irinotecan+BEV as second-line therapy for metastatic colorectal cancer: a randomised noninferiority trial27
Response to: Genetic risk scores may compound rather than solve the issue of prostate cancer overdiagnosis (BJC-LT3342090)26
The long noncoding RNA lncZBTB10 facilitates AR function via S-palmitoylation to promote prostate cancer progression and abiraterone resistance26
Genome-wide polygenic risk scores for colorectal cancer have implications for risk-based screening26
A study of subjective memory impairment in long-term testicular cancer survivors26
Correction: DKC1 enhances angiogenesis by promoting HIF-1α transcription and facilitates metastasis in colorectal cancer26
The Rac1-USP11 feedback amplification loop: a radiation-activated engine driving radioresistance in hepatocellular carcinoma26
Understanding genetic architecture of breast cancer: how can proteome-wide association studies contribute?26
Experimental Cancer Medicine Centre (ECMC) network proposal for a consensus gene panel for pan-cancer sequencing: a Delphi methodology26
Interventional pharmacoeconomics for immune checkpoint inhibitors through alternative dosing strategies26
Hormone replacement therapy and cancer mortality in women with 17 site-specific cancers: a cohort study using linked medical records26
Dynamic nature of BRAF or KRAS p.G12C mutations in second-line therapy for advanced colorectal cancer patients: do early and late effects exist?26
A combination of intrinsic and extrinsic features improves prognostic prediction in malignant pleural mesothelioma25
Exploratory biomarkers for oxaliplatin-induced nivolumab responsiveness in metastatic microsatellite-stable colorectal cancer25
Tumour-based epigenetic signatures as markers of prostate cancer aggressiveness after radical prostatectomy25
Natural immunity to SARS-CoV-2 and breakthrough infections in vaccinated and unvaccinated patients with cancer25
Anti-angiogenic therapy using the multi-tyrosine kinase inhibitor Regorafenib enhances tumor progression in a transgenic mouse model of ß-cell carcinogenesis25
Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA225
Tumour microenvironment characterisation to stratify patients for hyperthermic intraperitoneal chemotherapy in high-grade serous ovarian cancer (OVHIPEC-1)25
UDP-glucose ceramide glucosyltransferase promotes radioresistance via membrane reorganization to maintain redox balance in glioblastoma25
Risk-reducing mastectomy and breast cancer mortality in women with a BRCA1 or BRCA2 pathogenic variant: an international analysis25
Mutation of the proline P81 into a serine modifies the tumour suppressor function of the von Hippel–Lindau gene in the ccRCC25
Prognostic relevance of HRDness gene expression signature in ovarian high-grade serous carcinoma; JGOG3025-TR2 study25
Regulatory T cells induce a suppressive immune milieu and promote lymph node metastasis in intrahepatic cholangiocarcinoma25
ctDNA variations according to treatment intensity in first-line metastatic colorectal cancer25
Functional footprints of homologous recombination deficiency in prostate cancer revealed by ctDNA fragmentation and transcription factor accessibility24
Associations between serum glucose, insulin, insulin resistance and the risk of incident primary liver cancer or chronic liver disease mortality: a nested case–control study24
AKT/mTOR as a targetable hub to overcome multimodal resistance to EGFR inhibitors in oesophageal squamous cell carcinoma24
Hypoxia-inducible factor 3α1 increases epithelial-to-mesenchymal transition and iron uptake to drive colorectal cancer liver metastasis24
Artificial intelligence-driven microRNA signature for early detection of gastric cancer: discovery and clinical functional exploration24
Pre-diagnostic circulating untargeted metabolomics and risk of overall and clinically significant prostate cancer: a systematic review and meta-analysis24
Targeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer24
Prognostic value of post-operative iron biomarkers in colorectal cancer: population-based patient cohort24
Editorial Expression of Concern: Extracellular, cell-permeable survivin inhibits apoptosis while promoting proliferative and metastatic potential24
A digital quality measure for emergency presentation of pancreatic cancer24
Inhibition of the AURKA/YAP1 axis is a promising therapeutic option for overcoming cetuximab resistance in colorectal cancer stem cells24
Comparison of methods for cancer stem cell detection in prognosis of early stages NSCLC24
Birthweight, height, and body mass index in relation to the expression of stem cell markers among women with benign breast biopsies in the Nurses’ Health Study II23
The emergence of RAS mutations in patients with RAS wild-type mCRC receiving cetuximab as first-line treatment: a noninterventional, uncontrolled multicenter study23
Intratumour heterogeneity, from hypothesis to the clinic23
Targeting the untargetable: RB1-deficient tumours are vulnerable to Skp2 ubiquitin ligase inhibition23
Multicentric validation of diagnostic tests based on BC-116 and BC-106 urine peptide biomarkers for bladder cancer in two prospective cohorts of patients23
Comment on: “Neoadjuvant chemotherapy is noninferior to chemoradiotherapy for early-onset locally advanced rectal cancer in the FOWARC trial”23
PRRX1-TOP2A interaction is a malignancy-promoting factor in human malignant peripheral nerve sheath tumours23
Breast density is strongly associated with multiparametric magnetic resonance imaging biomarkers and pro-tumorigenic proteins in situ23
Attention-based deep learning for breast lesions classification on contrast enhanced spectral mammography: a multicentre study23
Epithelial−mesenchymal transition induced by tumor cell-intrinsic PD-L1 signaling predicts a poor response to immune checkpoint inhibitors in PD-L1-high lung cancer23
Role of 18F-FDG-PET/CT in the initial staging of very high-risk Ewing Sarcoma in a prospective multicentric Phase II Study: Is there still a place for bone marrow sampling?23
HDAC4 promotes the growth and metastasis of gastric cancer via autophagic degradation of MEKK323
Retraction Note: CDK5RAP3 as tumour suppressor negatively regulates self-renewal and invasion and is regulated by ERK1/2 signalling in human gastric cancer23
Modelled mortality benefits of multi-cancer early detection screening in England23
Unlocking hidden potential: advancements, approaches, and obstacles in repurposing drugs for cancer therapy23
Editorial Expression of Concern: Upregulation of p27 and its inhibition of CDK2/cyclin E activity following DNA damage by a novel platinum agent are dependent on the expression of p2122
Proactive monitoring of drug–drug interactions between direct oral anticoagulants and small-molecule inhibitors in patients with non-small cell lung cancer22
A liquid biopsy signature for predicting early recurrence in patients with gastric cancer22
Evolving roles of CD38 metabolism in solid tumour microenvironment22
Modeling response to the KRAS-G12C inhibitor AZD4625 in KRASG12C NSCLC patient-derived xenografts reveals insights into primary resistance mechanisms22
Chemotherapy-induced neuropathy in monomethyl Auristatin E treatment: prevention by lithium22
Semi-mechanistic efficacy model for PARP + ATR inhibitors—application to rucaparib and talazoparib in combination with gartisertib in breast cancer PDXs22
Single-cell sequencing reveals VEGFR as a potential target for CAR-T cell therapy in chordoma21
Dynamic changes in longitudinal circulating tumour DNA profile during metastatic colorectal cancer treatment21
First-line oxaliplatin-based chemotherapy and nivolumab for metastatic microsatellite-stable colorectal cancer—the randomised METIMMOX trial21
The importance of long-term follow up of participants in clinical trials21
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