OOIR: Observatory of International Research

Papers

(The TQCC of Laboratory Medicine is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Type 1 von Willebrand Disease in a Pediatric Patient Caused by a Novel Heterozygous Deletion of Exons 1 to 6 of the von Willebrand Factor Gene: A Case Report	37
A simple method to overcome paraproteinemic interferences in chemistry and immunoassays	22
Retrospective comparison of false-positive result frequencies of 3 syphilis serology screening tests in pregnant and nonpregnant patients at an academic medical center in Appalachia	20
Comparison of Commercial Low Molecular Weight Heparin and Homemade Anti-Xa Calibrators to a Commercial Specific Anti-Xa Calibrator for Plasma Rivaroxaban Quantification by Anti-Xa Oral Anticoagulant P	16
To Reflex or Not to Reflex: A Time and Cost-Effectiveness Analysis of Autocontrol with Reflex DAT versus Direct DAT	16
Laboratory Predictors of COVID-19 Pneumonia in Patients with Mild to Moderate Symptoms	14
Methods to Correct Drug-Induced Coagulopathy in Bleeding Emergencies: A Comparative Review	14
Long-Term Dynamic of Anti-TrimericS and Anti-RBD Antibodies in Naive and COVID-19 Recovered mRNA-1273 Vaccine Recipients	11
Absolute CD4 count and percentage values among Libyan patients with HIV by single-platform flow cytometry	10
Clinical Application of Prostatic Exosomal Protein and Prostate-Specific Antigen Levels in the Detection of Prostate-Related Diseases	10
Gas Chromatography Mass Spectrometry Aided Diagnosis of Glutathione Synthetase Deficiency	10
Quantitative Value of Bacteria Associated with Leukocytes in Differential Diagnosis of Lower Respiratory Tract Infection in Children, in Comparison to Sputum Culture and Procalcitonin	10
High C-Reactive Protein-to-Lymphocyte Ratio Is Predictive of Unfavorable Prognosis in HBV-Associated Decompensated Cirrhosis	9
Pentraxin 3 stability in serum and urine samples at –20 °C during a 4-week period	9
Development of an LC-MS/MS Method for Measurement of Irinotecan and Its Major Metabolites in Plasma: Technical Considerations	9
Diagnostic stewardship of procalcitonin testing by implementation of computer-based decision support	9
Differential Effects on HbA1c Detection by HPLC and Capillary Electrophoresis in Five Types of Hb Variants in China	8
Patient-derived reference intervals for alkaline phosphatase to support appropriate utility for isoenzymes determinations and hypophosphatasia	8
Correction: The Importance of Medical Laboratory Scientists and the Number of Doctoral Scientists that Began Their Career by Working on the Front Lines of Laboratory Medicine	7
Macroprolactinoma-Induced Syndrome of Inappropriate Antidiuresis and Its Reversal with Dopamine Agonist Therapy	7
The Dismal History of Cancer Treatment and Ongoing Racial Disparities	7
Elevated Lactate Dehydrogenase Concentrations in Plasma Compared to Serum	7
IgA is the predominant isotype of anti-β2 glycoprotein I in patients with COVID-19	7
D-Dimer Combined With CRP Can Improve the Differential Value of Bacterial Meningitis and Tuberculous Meningitis	7
IgM Warm Autoantibodies Causing Autoimmune Hemolytic Anemia in a Pediatric Patient	7

Double-stranded DNA antibody test using BioPlex220 system: unacceptable option for SLE diagnosis and follow-up	7
Imbalance of Circulating Monocyte Subsets in Subjects with Newly Emerged and Recurrent Hospital-Acquired Pneumonia	6
Chemerin Levels in Acute Coronary Syndrome: Systematic Review and Meta-Analysis	6
Prospective Validation of a Machine Learning Model for Low-Density Lipoprotein Cholesterol Estimation	6
Association of Plasma Fibrinogen Levels on Postoperative Day 1 with 2-Year Survival of Orthotopic Liver Transplantation for HBV-Related HCC	6
The Continued Need for the Routine Assessment of Folate Status	6
Associations between glycemic status and the ratio of γ-glutamyl transferase to HDL-C in middle-aged women	6
The Direct Spectrophotometric Method Is Reliable for Initial Assessment of Total Bilirubin in Neonatal Venous Plasma	6
Clinical Educators’ Teaching Approaches and Attributes in Laboratory Medicine	6
Vitamin D Status in Palindromic Rheumatism: A Propensity Score Matching Analysis	6
About the Journal	6
Combined Diagnosis of SARS-CoV-2: Rapid Antigen Detection as an Adjunct to Nucleic Acid Detection	6
Long-term alliance for pathology equipment and technology acquisition: a paradigm shift for improved quality and efficiency	5
Association of Interleukin-6 Polymorphisms with Schizophrenia and Depression: A Case-Control Study	5
Reduced Immune Response and Neutralizing Antibody Activity to the SARS-CoV-2 Vaccination in Patients with a History of Solid Organ Transplant	5
A Novel Homozygous Pathogenic Variant in CYP11B1 in a Female Iranian Patient with 11B Hydroxylase Deficiency	5
Neutrophilic Myeloid-Derived Suppressor Cells and Severity in SARS-CoV-2 Infection	5
Approaches to nonlinear curve fitting in laboratory medicine	5
The FDA’s proposed rule on laboratory-developed tests: what happens next?	5
Urine Organic Acid Analysis: Key Diagnostic Test for Fumaric Aciduria in a Sri Lankan Child	5
Value of Thyroid Peroxidase Antibodies in Neuroimmune Diseases: Analysis of Interference During Treatment with Intravenous Immunoglobulins	5
Insulin receptor substrate 2 gene Gly1057Asp polymorphism is a risk factor for nonalcoholic fatty liver disease	5
CALR frameshift mutation detection in myeloproliferative neoplasms by microfluidic chip analysis	5
A Novel INS Mutation in the C-Peptide Region Causing Hyperproinsulinemic Maturity Onset Diabetes of Youth Type 10	5
External quality assurance experience with Royal College of Pathologists of Australasia Program at an academic hospital in South Africa	5
Bronchoalveolar lavage cytology in children with chronic unexplained cough and severely neurologically impaired children	5
Patent blue interferes with the measurement of lipemia index in a patient with sentinel lymph node	4
Serum IL-6 and TNF-α Levels Are Correlated with Disease Severity in Patients with Ankylosing Spondylitis	4
A historical perspective on diversity in Clinical Laboratory Sciences Programs	4
Association between Serum α-Klotho Levels and Behçet Disease	4
Lipidomic analysis of serum exosomes identifies a novel diagnostic marker for type 2 diabetes mellitus	4
Platelet MicroRNA-484 as a Novel Diagnostic Biomarker for Acute Coronary Syndrome	4
Plasmablastic transformation of chronic lymphocytic leukemia: a review of literature and report on 2 cases	4
Correlation of the abundance of MDSCs, Tregs, PD-1, and PD-L1 with the efficacy of chemotherapy and prognosis in gastric cancer	4
The microbiological diagnostic performance of metagenomic next-generation sequencing in patients with infectious diseases	4
3D Printing as an Effective Quality Assurance Implementation in Massive-Scale SARS-CoV-2 Testing at a SwabSeq Next-Generation Sequencing Laboratory	4
Corrigendum to: A Simple and Applicable Method for Human Platelet Lysate Preparation Using Citrate Blood	4
Evusheld, a SARS-CoV-2 spike protein–directed attachment inhibitor, appears in serum protein electrophoresis and immunofixation: a case study	4
Transfusion-Related Acute Lung Injury Caused by HLA-II Antibodies: A Case Report	4
SNAP25 as a prognostic marker in transcriptome analysis of meningioma	4
Analysis of the Relationship between Bladder Cancer Gene Mutation and Clinical Prognosis by High-Throughput Sequencing	4
Genetic analysis of TMPRSS6 catalytic domain variants in Mexican patients with iron treatment refractoriness	4
Optimization of laboratory diagnosis of heparin-induced thrombocytopenia using HemosIL-AcuStar-HIT-IgG assay	4
Falsely Elevated Estradiol Results in a 62-Year-Old Male Patient	4
Acute hemolytic transfusion reaction caused by anti-M antibodies: a case report and literature review	4
MiR-150 Expression in Chronic Myeloid Leukemia: Relation to Imatinib Response	4
TP53 mutations in myeloid neoplasms: implications for accurate laboratory detection, diagnosis, and treatment	4
Analysis of platelet transfusion efficacy during extracorporeal membrane oxygenation (ECMO) treatment in pediatric patients post-cardiac surgery-a retrospective cohort study	4
Transient Pseudothrombocytopenia Detected 8 Months After COVID-19 Vaccination	4
Medical laboratory scientist motivation to pursue graduate education	4

A Primer on Chimerism Analysis: A Straightforward, Thorough Review	3
Association of Catalase Gene Polymorphisms with Idiopathic Nephrotic Syndrome in a Chinese Pediatric Population	3
Validating the HPA-1 to -5 and -15 Detection by Homemade PCR-SSP, Real-Time PCR, and PCR-RFLP Methods	3
Lean methodology in health care practice: an example of application for clinical laboratory urinalysis processing	3
Correction to: Diagnostic value of pleural effusion Krebs von den Lungen-6 in malignant pleural effusion of patients with non–small cell lung cancer	3
A Case of Massive Fetal-Maternal Hemorrhage: Lessons Learned in Diagnosis and Treatment	3
The Interpretation of Mirror Pattern Bands During Oligoclonal Immunoglobulin Isoelectric Focusing Electrophoresis: A Retrospective Study	3
Frequencies of Anti-Troponin I vs Anti-Troponin T Autoantibodies and Degrees of Interference on Troponin Assays	3
Evaluation of methods to eliminate analytical interference in multiple myeloma patients with spurious hyperphosphatemia	3
Resolving Pseudohyponatremia: Validation of Plasma Sodium on Radiometer ABL800 Blood Gas Analyzers for Immediate Reflex Testing	3
Comparison of IgG Against COVID-19 Between Postmenopausal and Nonmenopausal Women Vaccinated With Sinopharm Vaccine	3
Quality Assessment and Clinical Utility of Plasma Obtained Via Apheresis vs That Obtained from Whole Blood	3
Alteration of circulating miRNAs during myocardial infarction and association with lipid levels	3
Combination of Circulating Cell-Free DNA and Positron Emission Tomography to Distinguish Non–Small Cell Lung Cancer from Tuberculosis	3
A 6-year-old boy with an atypical liver neoplasm harboring a novel RPS6KA3 variant	3
Trimethylamine-N-Oxide and Precursors as Novel Potential Biomarkers for Anxiety Disorder	3
Identification of Differential Metabolites Between  Type 2 Diabetes and Postchronic Pancreatitis Diabetes (Type 3c) Based on an Untargeted Metabolomics Approach	3
About the Journal	3
Metagenomic next-generation sequencing for the identification of infections caused by Gram-negative pathogens and the prediction of antimicrobial resistance	3
Thrombin-antithrombin complex might be a promising parameter for monitoring anticoagulation in the early postoperative period after LVAD implantation	3
Prediction of low-density lipoprotein cholesterol levels using machine learning methods	3
From A to AB: A Caucasian Mother with High Anti-B Titer Causing Hemolytic Disease of the Newborn	3
A Scoping Review of Medical Laboratory Science and Simulation: Promoting a Path Forward with Best Practices	3
Semaphorin 3A levels in vascular and nonvascular phenotypes in systemic sclerosis	3
Performance of High Throughput SARS-CoV-2 Antigen Testing Compared to Nucleic Acid Testing	3
EDTA-Induced Pseudothrombocytopenia up to 9 Months after Initial COVID-19 Infection Associated with Persistent Anti-SARS-CoV-2 IgM/IgG Seropositivity	2
Increased Levels of ANGPTL3 and CTRP9 in Patients With Obstructive Sleep Apnea and Their Relation to Insulin Resistance and Lipid Metabolism and Markers of Endothelial Dysfunction	2
A Century of Progress	2
Kanamycin Supplement for the Disaggregation of Platelet Clumps in EDTA-Dependent Pseudothrombocytopenia Specimens	2
Autoantibodies in laryngeal cancer: detection and role as a biomarker	2
Improvement in Platelet Product Wastage and Reduction of Costs through Implementation of the Pan Genera Detection Test	2
Correction	2
Vortexing specimens to disaggregate platelet clumps in EDTA specimens	2
Acquired Factor VIII Inhibitors: A Case Study	2
Urinary MMP-7: A Predictive, Noninvasive Early Marker for Chronic Kidney Disease Development in Patients with Hypertension	2
Storage Duration and Red Blood Cell–Derived Microparticles in Packed Red Blood Cells Obtained from Donors with Thalassemia	2
Evaluation of the Preanalytical Interference of Hemoglobin, Bilirubin, or Lipids in Therapeutic Drug Monitoring Assays on Beckman Coulter AU Analyzers	2
Retrospective Assessment of a National Reflex Cryptococcal Antigen Screening Program in South Africa Through Interlaboratory Comparison of Lateral Flow Assay Results	2
Increases in CLIA-Waived Testing Sites Since the Start of the COVID-19 Pandemic	2
Assessment of the Stability of Midregional Proadrenomedullin in Different Biological Matrices	2
Whole-Exome Sequencing Revealed a Pathogenic Nonsense Variant in theSLC19A2Gene in an Iranian Family with Thiamine-Responsive Megaloblastic Anemia	2
Hsa-miR-2113-5p is not a key indicator for coronary artery disease: a case-controlled observational study	2
Verifying the nonreporting hemolysis index for potassium, phosphate, magnesium, AST, LDH, iron, CA 19-9, and vitamin D, using Beckman Coulter AU5800 and DxI800 automated analyzers	2
About the Journal	2
The identification of diurnal variations on circulating immune cells by finger prick blood sampling in small sample sizes: a pilot study	2
The Importance of Medical Laboratory Scientists and the Number of Doctoral Scientists that Began Their Career by Working on the Front Lines of Laboratory Medicine	2
COP27 Climate Change Conference: Urgent Action Needed for Africa and the World	2
Serologic detection of regenerating protein I alpha by time-resolved fluoroimmunoassay and its clinical value in gastric cancer	2
Familial nonmedullary thyroid cancer: a case series in Iranian patients with a meta-review of case series	2
Molecular and phenotypical findings of a novel de novo SYNGAP1 gene variant in an 11-year-old Iranian boy with intellectual disability	2
Bone marrow reinvestigation leading to the diagnosis of VEXAS syndrome	2
A Novel Mutation of the Membrane Metallo-Endopeptidase Gene Related to Late-Onset Hereditary Polyneuropathy: Case Report and Review of the Literature	2
Therapeutic plasma exchange for hyperviscosity syndrome in IgA multiple myeloma	2
College of American Pathologists Quality Cross Check —Chemistry and Therapeutic Drug Monitoring as a tool for biannual instrument correlations	2
Anti-E alloimmunization from a platelet apheresis transfusion in a 22-month-old male with acute myeloid leukemia	2
Automated detection of free monoclonal light chains by enhanced-sensitivity modified immunofixation electrophoresis with antisera against free light chains	2
Quantitative Detection of House Dust Mites–Specific IgE by Light-Initiated Chemiluminescence Assay	2
Total Analytical Error and Measurement Uncertainty for Analytical Performance Evaluation and Determination of Gray Zones of Glucose Critical Value Limits	2
Early detection of myocardial infarction with reference to baseline levels during health: impact on biological variation of high-sensitivity cardiac troponin	2
Predictors of mortality and transfusion requirements in venoarterial extracorporeal membrane oxygenation patients	2
Urinary Exosomes: A Promising Biomarker for Disease Diagnosis	2
Reactogenicity and Peak Anti-RBD-S1 IgG Concentrations in Individuals with No Prior COVID-19 Infection Vaccinated with Different SARS-CoV-2 Vaccines	2
Unexpectedly Abnormal Electrolytes in a 60 Year Old Man with Dementia	2
Association of SLC22A1,SLCO1B3 Drug Transporter Polymorphisms and Smoking with Disease Risk and Cytogenetic Response to Imatinib in Patients with Chronic Myeloid Leukemia	2
Multisite Pseudomonas aeruginosa Infections Detected by Metagenomic Next-Generation Sequencing in a Child with Aplastic Anemia: A Case Report	2
Pathogenic Homozygous Mutations in the DBT Gene (c.1174A>C) Result in Maple Syrup Urine Disease in a rs12021720 Carrier	2
A Persistent Positive Antibody Test in a Patient with No History of COVID-19 Infection	2
Uncommon causes of hemoglobin E flags identified during measurement of hemoglobin A1c by ion-exchange high-performance liquid chromatography	2
Analytical evaluation of the automated interleukin-6 assay on the Roche cobas e602 analyzer	2
Correction to: A meta-analysis of the accuracy of Xpert MTB/RIF in diagnosing intestinal tuberculosis	2
Resazurin microplate test method for rapid determination of colistin resistance in carbapenem-resistant Acinetobacter baumanii isolates	2
Diagnostic value of pleural effusion Krebs von den Lungen-6 in malignant pleural effusion of patients with non–small cell lung cancer	2