Chemical & Pharmaceutical Bulletin

Article	Citations
Development of Ethylcellulose Microparticles for Taste Masking of Fexofenadine	50
Advances in Preparation of Peptide and Protein Thioesters Aiming to Use in Medicinal Sciences	34
Rapid Determination of Dapagliflozin in Rat Plasma by UHPLC-Q-Orbitrap MS and Its Application to a Pharmacokinetic Study	18
Foreword	17
Concise and Highly Stereoselective Synthesis of <i>β</i>,<i>β</i>-Disubstituted <i>α</i>,<i>β</i>-Unsaturated Esters	17
Clinical Pipelines for Alzheimer’s Disease Psychosis and Agitation	17
Errata for Chemical and Pharmaceutical Bulletin	16
MiR-135a Protects against Myocardial Injury by Targeting TLR4	16
<i>In Vitro</i> and <i>in Silico</i> Studies of Potential Coronavirus-Specific 3C-Like Protease Inhibitors	15
Leonurine Preconditioning Attenuates Ischemic Acute Kidney Injury in Rats by Promoting Nrf2 Nuclear Translocation and Suppressing TLR4/NF-κB Pathway	14
Design, Synthesis, and Biological Evaluation of Water-Soluble Prodrugs of C5-Curcuminoid GO-Y030 Based on Reversible Thia-Michael Reaction	14
Protective Effect of Apple Polyphenols on H<sub>2</sub>O<sub>2</sub>-Induced Oxidative Stress Damage in Human Colon Adenocarcinoma Caco-2 Cells	14
CBDPS 1.0: A Python GUI Application for Machine Learning Models to Predict Bitter-Tasting Children’s Oral Medicines	14
Photoinduced Atom Transfer Radical Addition Reaction of Olefins with α-Bromo Carbonyls	13
Teleocidin Analogs Isolated from <i>Streptomyces eurocidicus</i> as Membrane-Vesicle-Regulated Natural Products	12
Synthesis and Evaluation of Novel Triaryl Derivatives with Readthrough-Inducing Activity	12
Syntheses of Aryl Thioethers <i>via</i> Aromatic Substitution of Aryl Halides at 0 to 25 °C	12
Viscosity-Induced Emission of 5-(Diarylmethylene)imidazolone with Extended Conjugation <i>via</i> Attachment of <i>N</i>-Methylpyrrole at the 2-Position	11
Effect of Two-Photon Excitation to 8-Azacoumarin Derivatives as Photolabile Protecting Groups	11
Development of Efficient Synthetic Reactions Using Enamines and Enamides Carrying Oxygen Atom Substituent on Nitrogen Atom	11
Site-Specific Tritium Labeling at the Predefined Internal Position of the Chemically-Modified RNA	11
Oxygen-Fueled Iterative Hydride Transfer Driven by a Rigid Planar Architecture	10
<i>In Vitro</i> Study on Combined Effect of Drugs for Hyperphosphatemia on Phosphorus Adsorption Capacity	10
Synthesis of 2-Substituted Indoles <i>via</i> Migration Reaction of 3-Substituted Indoles with Triflic Acid	10
Substituent Effects at the <i>N</i>-Nitrosoaminophenol Moiety of a Photoinduced-Electron-Transfer-Driven Nitric Oxide Releaser	10

Natural Compounds with BMI1 Promoter Inhibitory Activity from <i>Mammea siamensis</i> and <i>Andrographis paniculata</i>	10
Design, Synthesis, and Characterization of 1-(Anthracen-9-ylmethyl)-1,5,9-triazacyclododecane (Ant-[12]aneN3) and Its DNA Photocleavage Activity	10
Development of a Potential-Modulated Electrochemiluminescence Measurement System for Selective and Sensitive Determination of the Controlled Drug Codeine	9
Elucidation of Degradation Behavior of Barbiturates in Artificial Gastric Juice: Study on Degradability of Drugs in Stomach (V)	9
Optimization and Advantages of Molded Tablets Using Trehalose as a Binder	9
Bromine K-Edge X-Ray Absorption Near-Edge Structure Analysis on Hydrobromide-Salt Crystals and the Solid Dispersion of Active Pharmaceutical Ingredients	9
Unusual Enzymatic C–C Bond Formation and Cleavage Reactions during Natural Product Biosynthesis	9
Synthesis of Coumarin-Conjugated Oligonucleotides <i>via</i> Knoevenagel Condensation to Prepare an Oligonucleotide Library	9
Anti-hepatitis C Virus Activity of Juglorubin Derivatives	9
Functions, Structures, and Engineering of the Teleocidin Biosynthetic Enzymes	8
The Effect of Iontophoresis with and without Electroporation on the Penetration of High Molecular Compounds into the Stratum Corneum	8
Evaluation of the Mechanism of Phosphate Removal Using Oyster Shell Powder in Aqueous Environments	8
Near-Infrared Metabolic Profiling for Discrimination of Apricot and Peach Kernels	8
<i>p</i>-Methoxy- and 2,4-Dimethoxybenzyl <i>N</i>-Acetylcarbamate Potassium Salts: Versatile Reagents for <i>N</i>-Alkylacetamide and <i>p</i>-Methoxy-	8
Rapid Structure Determination of Ranitidine Hydrochloride API in Two Crystal Forms Using Microcrystal Electron Diffraction	8
Molecular Modeling, Synthesis, and Preliminary Cytotoxicity Evaluation of New Indole-Based Molecules as Possible Sirtuin Inhibitors	8
Liquid Chromatographic Determination of <i>o</i>-Phosphoethanolamine in Human Plasma Using Fluorescent Derivatization	8
Transport Characteristics of Placenta-Derived Extracellular Vesicles and Their Relevance to Placenta-to-Maternal Tissue Communication	8
Solid Fat Content and Relaxation Time Measurement of Petrolatum Using Time-Domain NMR, and the Correlation with Viscosity and Crystallinity	8
Isolation and Structure Elucidation of JBIR-157, a Skeletally Novel Aromatic Polyketide Produced by the Heterologous Expression of a Cryptic Gene Cluster	7
Effects of Physicochemical Properties of Constituent Ions of Ionic Liquid on Its Permeation through a Silicone Membrane	7
Optimization of the Hydrothermal Activation Treatment with Sodium Hydroxide Solution for the Conversion of Coal Fly Ash to Zeolite and Its Adsorption Capability of Lead (II) Ions from the Liquid Phase	7
8-Iodoisoquinolinone, a Conformationally Rigid Highly Reactive 2-Iodobenzamide Catalyst for the Oxidation of Alcohols by Hypervalent Iodine	7
Theoretical Study of the Mechanism of Ribosomal Peptide Bond Formation Using the ONIOM Method	7
Total Synthesis of (+)-Silybin A	7
Amino Acids and Their <i>N</i>-Acetylated Derivatives Maintain the Skin’s Barrier Function	7
Palatability of Aripiprazole Gummies Prepared from Commercially Available Products: Pharmaceutical Formulation for Improving Patient Adherence	7
<i>N</i>-Nitrosodimethylamine (NDMA) Formation from Ranitidine Impurities: Possible Root Causes of the Presence of NDMA in Ranitidine Hydrochloride	7
Two New Halimanes with a <i>γ</i>-Lactone from <i>Croton argyratus</i>	7
Flip-Flop Promotion Mechanisms by Model Transmembrane Peptides	7
Enteric Microcapsules Encapsulation of Roxithromycin-PVP Composite Core Particles to Inhibit Drug Crystallization upon Fluidized Bed Method for Oral Administration	7
Development of Low Molecular Weight Ligands for Integrin α<sub>v</sub>β<sub>3</sub>	7
Discovery of a Novel Lidocaine Metabolite by Human Liver Microsome and Identification of Microbial Species Which Produces the Same Metabolite	7
Chlorocyclization of Alkenoic Thioester	7
Construction of 7-Diethylaminocoumarins Promoted by an Electron-Withdrawing Group	7
Toward the Synthesis of Strychnos Alkaloids: Effective Construction of Fused Cyclohexane and Pyrrolidine Portion of the Strychnos Skeleton <i>via</i> Domino Intermolecular and Intramolecul	7
Emerging Separation Techniques in Supercritical Fluid Chromatography	7
Masking the Taste of Fixed-Dose Combination Drugs: Particular NSAIDs Can Efficiently Mask the Bitterness of Famotidine	7
Site-Selective Molecular Transformation: Acylation of Hydroxy Groups and C–H Amination	6
Functional Peptides That Target Biomembranes: Design and Modes of Action	6
Magnetic Field-Responsive Pulsatile Drug Release Using A Magnetic Fluid	6
C21 Steroidal Glycosides from the Roots of <i>Oxypetalum caeruleum</i>	6
A Tricyclic Aromatic Polyketide Isolated from the Marine-Derived Fungus <i>Curvularia aeria</i>	6
Synthesis and Evaluation of DHMEQ Derivatives with Tertiary Hydroxyl Group Instead of Secondary Hydroxyl Group	6
Estimation for Raw Material Plants of a Henna Product Using LC-High Resolution MS and Multivariate Analysis	6
Simultaneous Overcoming Approach for Poor Wettability and Low Stability in Stomach by Simple Methods; Formulation Design and Development of Monoacylglycerol Acyltransferase 2 Inhibitor, S-309309	6
Identification of a Functionally Efficient and Thermally Stable Outward Sodium-Pumping Rhodopsin (<i>Be</i>NaR) from a Thermophilic Bacterium	6
Antiproliferative Activities of Diterpenes from Leaves of <i>Isodon trichocarpus</i> against Cancer Stem Cells	6
Exosome-Hijacking Drug Delivery System with Branched Arginine Linker Effectively Deliver Antisense Oligonucleotides into Lung Adenocarcinoma Cells	6
Isosteric Replacement of Ester Linkage of Lysophospholipids with Heteroaromatic Rings Retains Potency and Subtype Selectivity	6

Organocatalyzed Amine-Free <i>O</i>-Phosphorylation of Alcohols with 4-Methylpyridine <i>N</i>-Oxide	6
Novel Pharmaceutical Cocrystals and Solvate Crystals of Nobiletin, a Citrus Flavonoid with Potent Pharmacological Activity	6
A Review on the Foodomics Based on Liquid Chromatography Mass Spectrometry	6
Self-assembly of Urea Derivatives into Supramolecular Gels	6
Foreword	6
Application of Quantitative NMR (qHNMR) towards Establishment of Pharmaceutical Reference Standard; A Case of a Ticagrelor Process Impurity	6
Errata for Chemical and Pharmaceutical Bulletin	5
C–H▪▪▪S Hydrogen Bonds in Ampicillin and Amoxicillin Crystals Investigated by Sulfur K-Edge X-Ray Absorption Near-Edge Structure Spectroscopy and Single-Crystal X-Ray Structure Analysis	5
μ-Oxo-Hypervalent-Iodine-Catalyzed Oxidative C–H Amination for Synthesis of Benzolactam Derivatives	5
Methylene Blue Removal from the Aqueous Phase Using a Magnetic-Calcined Bamboo Composite Adsorbent	5
New Candidate Preservative in Ophthalmic Solution Instead of Benzalkonium Chloride: 1,3-Didecyl-2-methyl Imidazolium Chloride	5
Comparison of Phosphate and Bicarbonate Buffer Solutions as Dissolution Test Media for Predicting Bioequivalence of Febuxostat Formulation	5
Development of Highly Sensitive Method for Sugar Determination in Herbal Medicine; Application of Monosaccharides and Oligosaccharides in Japanese Angelica Root and Rehmannia Root	5
Cellular Uptake and Transport Characteristics of FL118 Derivatives in Caco-2 Cell Monolayers	5
Comparison of Growth in <i>Hydrangea macrophylla</i> var. <i>thunbergii</i> Grown in Different Soil pH and Quantitative Analysis of Its Sweetness-Related Constituents	5
Synthetic Studies on Vitamin D Derivatives with Diverse but Selective Biological Activities	5
Effect of Solubility Improvement <i>via</i> Formation of an Amorphous Composite of Indomethacin and Sulindac on Membrane Permeability	5
Selective Synthesis of the Aminobutadiene Intermediate and Mechanistic Analysis of 1,4-Dihydropyridine Formation Reaction in Water	5
Errata for Chemical and Pharmaceutical Bulletin	5
First Total Syntheses of Natural Phenanthrene Alkaloids, Uvariopsamine, Noruvariopsamine, 8-Hydroxystephenanthrine, 8-Methoxyuvariopsine, Thalihazine, and Secophoebine, and Their Potential as Antimala	5
Synthesis, Duplex-Forming Ability, and Nuclease Resistance of Oligonucleotides Containing a Thymidine Derivative with a 1-Oxaspiro[4.5]decane Skeleton	5
Remarkable Solvent Effect of Fluorinated Alcohols on Azo–Ene Reactions	5
Guided Isolation of Isopentenyl Flavonoids from <i>Daphne giraldii</i> Based on the Combination of GNPS and SMART	5
Lewis Acid-Conjugated Pyrene Photoredox Catalyst Promoting the Addition Reaction of α-Silyl Amines with Benzalmalononitriles	5
Design, Synthesis and Cytotoxicity Evalufation of Substituted Benzimidazole Conjugated 1,3,4-Oxadiazoles	5
Effects of Membrane Cholesterol on Stability of Transmembrane Helix Associations	5
Physical Properties for Novel Cilostazol Co-amorphous; Effect of Preparation Method and Molar Ratio on the Co-amorphous	5
Sulfonate Derivatives Containing a Kakuol Moiety as Potential Fungicidal Candidates: Design, Synthesis and Antifungal Activity Evaluation	5
Preparation and <i>in Vitro</i> Evaluation of Osmotic-Pump Lorcaserin-hydrochloride Controlled-Release Tablets	4
Synthesis and Evaluation of Quinone Derivatives for Activity against <i>Trypanosome cruzi</i>	4
Dissolution Profiles of Oral Disintegrating Tablet with Taste Masking Granule Polymer Coating in Biorelevant Bicarbonate Buffer	4
Development of an Artificial Nucleic Acid Skeleton Allowing for Unnatural-Type Triplex DNA Formation with Duplex DNA Having a TA Inversion Site	4
Development of Fluorescent Estrogen Receptor Ligands with pH Sensor Functionality	4
Novel Strategies for Enantio- and Site-Selective Molecular Transformations	4
The New Delivery Strategy of Albumin Carrier Utilizing the Interaction with Albumin Receptors	4
Aqueous Dispersion Polymerization for the Development of Lamivudine-Polyacrylonitrile Nanoparticles through Quality by Design Approach	4
Chemical Components in <i>Hedera rhombea</i> Leaves and Their Cytotoxicity	4
GMP-Compliant Automated Radiolabeling and Quality Controls of [<sup>68</sup>Ga]Ga-FAPI-46 for Fibroblast Activation Protein-Targeted PET Imaging in Clinical Settings	4
Quantification of Risperidone Contained in Precipitates Produced by Tea Catechins Using Nuclear Magnetic Resonance	4
Exploring the Effectiveness of Carboxymethylated and Crosslinked <i>Albizia procera</i> Gum in Diltiazem Hydrochloride Matrix Tablets: A Comparative Analysis	4
Bivalent β-Carbolines Inhibit Colorectal Cancer Growth through Inducing Autophagy	4
Cyclopsammocinamides A and B, Enantiomeric Cyclic Peptides of Cyclocinamide A, from the Marine Sponge <i>Psammocinia</i> sp.	4
Structural Characterization of Zinc(II)/Cobalt(II) Complexes of Chiral <i>N</i>-(Anthracen-9-yl)methyl-<i>N</i>,<i>N</i>-bis(2-picolyl)amine and Evaluation of DNA P	4
Liquiritigenin Attenuated Collagen-Induced Arthritis and Cardiac Complication <i>via</i> Inflammation and Fibrosis Inhibition in Mice	4
Structure–Activity Relationships of UTX-121 Derivatives for the Development of Novel Matrix Metalloproteinase-2/9 Inhibitors	4
Five New Analogs of Streptogramin Antibiotic Viridogrisein Isolated from <i>Streptomyces niveoruber</i>	4
Effect of Sample Concentration on Nanoparticle Tracking Analysis of Small Extracellular Vesicles and Liposomes Mimicking the Physicochemical Properties of Exosomes	4
Compounds Designs of CK2α Inhibitors Derived from Virtual Screening Hit Compounds by Computational Chemistry with Crystallography	4
Uric Acid as a Photosensitizer in the Reaction of Deoxyribonucleosides with UV Light of Wavelength Longer than 300 nm: Identification of Products from 2′-Deoxycytidine	4
Purity Determination of Cyclophosphamide Hydrate by Quantitative <sup>31</sup>P-NMR and Method Validation	4
Effect of Equipment Parameters on Amount and Dispersion of Wetting Liquid in Planetary Centrifugal Granulation	4
Effect of Particle Size of Powdered Cellulose Nanofibers as an Additive in the Production of Orally Disintegrating Mini-Tablets by Direct Powder Compression	4
Synthesis of Novel Pseudo-Enantiomeric Phase-Transfer Catalysts from <i>Cinchona</i> Alkaloids and Application to the Hydrolytic Dynamic Kinetic Resolution of Racemic 3-Phenyl-2-oxetanone	4
Construction of <i>N</i>-Heterocycles Fused with a Highly Substituted Benzene Ring by a Benzyne-Mediated Cyclization/Functionalization Cascade Reaction and Its Application to the Total Syn	4
An Amphipathic Structure of a Dipropylglycine-Containing Helical Peptide with Sufficient Length Enables Safe and Effective Intracellular siRNA Delivery	4
Epigenetic Inhibitors as Alzheimer’s Disease Therapeutic Agents	4
Electrochemical Characterization of a Novel Organoelectrocatalyst, 7-Azabicyclo[2.2.1]heptan-7-ol (ABHOL), and Its Application to Electrochemical Sensors	4
Protein Chemical Modification Using Highly Reactive Species and Spatial Control of Catalytic Reactions	4
2-Thioxothiazolidin-4-one Analogs as Pan-PIM Kinase Inhibitors	4
Shanpanootols G and H, Diterpenoids from the Rhizomes of <i>Kaempferia pulchra</i> Collected in Myanmar and Their Vpr Inhibitory Activities	4
Structure–Activity Relationships of Thiophene Carboxamide Annonaceous Acetogenin Analogs: Shortening the Alkyl Chain in the Tail Part Significantly Affects Their Growth Inhibitory Activity against Hum	4
Importance of the Azole Moiety of Cimetidine Derivatives for the Inhibition of Human Multidrug and Toxin Extrusion Transporter 1 (hMATE1)	4
Development and Validation of an LC–MS/MS-Based Method for Quantifying Urinary Endogenous 6-Hydroxymelatonin	4
A New 1,2-Naphthoquinone Derivative with Anti-lung Cancer Activity	4
Cyclosporin A Inhibits the Activation of Membrane-Bound Guanylate Cyclase GC-A of Atrial Natriuretic Factor <i>via</i> NAD(P)H Oxidase	4
Synthesis of Formononetin Derivatives and Cardioprotective Effects	4
Application of Quantitative NMR Spectroscopy to the Quality Evaluation of Diclofenac Gargles as Hospital Preparations	4
Triflimide-Promoted Nucleophilic <i>C</i>-Arylation of Halopurines to Access <i>N</i><sup>7</sup>-Substituted Purine Biaryls	4
Improved Dissolution Properties of Co-amorphous Probucol with Atorvastatin Calcium Trihydrate Prepared by Spray-Drying	4
Pyrrolactams from Marine Sponge <i>Stylissa massa</i> Collected from Myanmar and Their Anti-Vpr Activities	4
Development of a Fluorescence Probe for Detecting Nitroreductase Activity Based on Steric Repulsion-Induced Twisted Intramolecular Charge Transfer (sr-TICT)	4
Effects of Substituting Disubstituted Amino Acids into the Amphipathic Cell Penetrating Peptide Pep-1	4
Synthesis and Characterization of Novel Radioiodinated Triazole-Pyrolidine Derivative to Detect Orexin 2 Receptor in the Brain	4
An Update Mini-Review on the Progress of Azanucleoside Analogues	4
P(III)-Mediated Formal Reductive N–H Bond Insertion Reaction of Hydrazones to α-Keto Esters	3
Peptide Tool-Driven Functional Elucidation of Biomolecules Related to Endocrine System and Metabolism	3
Isolation and Identification of Three New Iridoid Glucosides from the Aerial Parts of <i>Paederia scandens</i>	3
Development and Full Validation of a Bioanalytical Method for Quantifying Letermovir in Human Plasma Using Ultra-Performance Liquid Chromatography Coupled with Mass Spectrometry	3
Palladium-Catalyzed C–H Arylation of [1,1′-Biphenyl]-2-ols with Chloroarenes	3
Synergistic Activation of TLR7 and 8 Mediated by Reduction of Electrostatic Repulsion	3

Extremely Simple and Rapid HPLC Analysis of Tocilizumab in Human Serum with Selective Precipitation Using Alkylamine	3
Formulation of Biopharmaceutical Dry Powder Inhaler Using the Void Forming Index (VFI) to Detect and Avoid Powder Caking in Dry Powder Inhaler Formulations	3
Evaluation of Time-Dependent Deformation Behavior of Pharmaceutical Excipients in the Tableting Process	3
Crystalline Phase Transitions of 5′-<i>O</i>-Triethylsilyl-2′-deoxy-5-azacytidine under Varying Temperature and Humidity Conditions and Its Closed Storage Stability	3
Advances in Understanding the Mechanism of Ophthalmic Viscosurgical Device Retention in the Anterior Chamber or on the Corneal Surface during Ocular Surgery	3
Ion-Pair Extraction with Tetracyanocyclopentadienides: A Method for Estimating Extraction Efficiency	3
Asymmetric Total Syntheses of Mitragynine, Speciogynine, and 7-Hydroxymitragynine	3
Foreword	3
Colloidal Particle in Suspensions of Maobushisaishinto Extract Granules Enhances Drug Intestinal Penetration	3
Development of Drug Discovery Platforms Using Artificial Intelligence and Cheminformatics	3
Oxidative Functionalization of Catechol Derivatives Substituted with Electron-Withdrawing Groups	3
Synthesis of Tetrahydrofuro[2,3-<i>d</i>]oxazoles and Oxazoles by Hypervalent Iodine (III)-Promoted [2 + 2 + 1] Annulation	3
Foreword	3
Elaboration of Non-naturally Occurring Helical Tripeptides as p53–MDM2/MDMX Interaction Inhibitors	3
Substrate Flexibilities of Norbelladine Synthase and Noroxomaritidine/Norcraugsodine Reductase for Hydroxylated and/or Methoxylated Aldehydes	3
Construction of 2,2-Dimethyloxepane Frameworks from Ene-Diols Catalyzed by Metal Catalyst or Brønsted Acid <i>via</i> 7-<i>Endo</i>-<i>Trig</i> Cyclization	3
Evaluation of STAT3 Inhibition by Cancer Chemopreventive Trichothecenes Derived from Metabolites of <i>Trichothecium roseum</i>	3
Total Synthesis and Antibacterial Activity of 5-Geranyloxy-7-hydroxycoumarin and Murrayacoumarin A	3
Development of Naturally Inspired Peptide and Protein Chemistry	3
Prediction of Intra-individual Variability in Bioequivalence Studies of 278 Formulations: Comprehensive Analysis Using Physicochemical and Pharmacokinetic Parameters	3
Bioequivalence Dissolution Test Criteria for Formulation Development of High Solubility-Low Permeability Drugs	3
Ruthenium-on-Carbon-Catalyzed Facile Solvent-Free Oxidation of Alcohols: Efficient Progress under Solid–Solid (Liquid)–Gas Conditions	3
Model Synthetic Study of Tutin, a Picrotoxane-Type Sesquiterpene: Stereoselective Construction of a <i>cis</i>-Fused 5,6-Ring Skeleton	3
Lipase-Catalyzed Kinetic Resolution of <i>C</i><sub>1</sub>-Symmetric Heterocyclic Biaryls	3
Development of Highly Sensitive Chemiluminescence Enzyme Immunostaining Assay to Determine Glycyrrhizin Content Using Anti-glycyrrhizin Monoclonal Antibody	3
Chemical Constituents of the Leaves of <i>Thujopsis dolabrata</i> and Their Cytotoxicity	3
Fragment Molecular Orbital Based Affinity Prediction toward Pyruvate Dehydrogenase Kinases: Insights into the Charge Transfer in Hydrogen Bond Networks	3
A Facile Method for the Quantification of Urinary Uracil Concentration by a Uracil-Specific Fluorescence Derivatization Reaction	3
Study of Polymer Nanofilms Using for High-Throughput Screening in the Development of Transdermal Therapeutic System	3
Analysis of Powder Properties of Pharmaceutical Excipients Using a Constant-Volume Shear Tester	3
12,20-Epoxypregnane Glycosides from the Roots of <i>Oxypetalum caeruleum</i>	3
Foreword	3
Determination of the Solid Content of Active Pharmaceutical Ingredient Powders in Suspension-Type Pharmaceutical Oral Jelly Using Time-Domain NMR	3
Highly Precise Anomaly Detection Using Multivariate Statistical Process Control with Appropriate Scaling of Input Variables in Pharmaceutical Continuous Manufacturing	3
Development of an Antigen Delivery System for a B Cell-Targeted Vaccine as an Alternative to Dendritic Cell-Targeted Vaccines	3
Hyaluronan Tetrasaccharides Penetrate into the Skin by Passive Diffusion and Contribute to Skin Health	3
Elucidating the Factors Affecting the Patient-Centric Usability of Blister Packs for Spherical Capsules	3
Foreword	3
Effect of Cultivation Conditions on Components of <i>Ephedra</i> sp. Using Liquid Chromatography-Mass Spectrometry and Multivariate Analysis	3
Improvement of Skin Permeation of Caffeine, a Hydrophilic Drug, by the Application of Water Droplets Provided by a Novel Humidifier Device	3
Discoveries and Syntheses of Highly Potent Antimalarial Troponoids	3
Theoretical Framework for Novel Catalytic Biomolecules Composed of Multiple Peptides	3
A Stereoselective Synthesis of Fused Carbocycles with a <i>cis</i>-1,2-Diol Moiety by Desymmetrization: SmI<sub>2</sub>-Mediated Pinacol Coupling of <i>meso</i>-Cyc	3
Determination of Hardness of a Pharmaceutical Oral Jelly by Using <i>T</i><sub>2</sub> Relaxation Behavior Measured by Time-Domain NMR	3
Correlation between Membrane Permeability and the Intracellular Degradation Activity of Proteolysis-Targeting Chimeras	2
Development of a Water Soluble Self-assembling Analogue of Vizantin	2
Cyclic Phthalate Esters as Liver X Receptor Antagonists with Anti-hepatitis C Virus and Anti-severe Acute Respiratory Syndrome Coronavirus 2 Properties	2
Functionalization of Siloxanes with Arynes Generated from <i>o</i>-Triazenylarylboronic Acids	2
Effect of Ag and Ni-Doped Cerium Oxide Nanoparticles on the Formation of ROS and Evaluation as an Alternative Physical Sunscreen Material	2
Biosynthesis of Bioactive Natural Products Derived from Theonellidae Family Marine Sponges	2
Antiproliferative Activities of Cynaropicrin and Related Compounds against Cancer Stem Cells	2
Neuroimmune Dysfunction in Alzheimer’s Disease and Other Forms of Dementia	2
Identification of Proteolysis Targeting Chimeras (PROTACs) for Lysine Demethylase 5 and Their Neurite Outgrowth-Promoting Activity	2
Research Progress on the Mechanism of Reducing Toxicity and Increasing the Efficacy of Sini Decoction Compatibility	2
Amide Bond Formation Using 4-Coumarate: CoA Ligase from <i>Arabidopsis thaliana</i>	2
Characterization of Ibuprofen-Loaded MgO by One-Step Mid- and Far-FT-IR Spectroscopy	2
Substitution Effects of Alkene Dipeptide Isosteres on Adjacent Peptide Bond Rotation	2
Chemical Constituents from the Leaves of <i>Pachyrhizus erosus</i> Collected in Vietnam	2
Astragaloside IV Inhibits the Pyroptosis in the Acute Kidney Injury through Targeting the SIRT1/FOXO3a Axis	2
Elucidating Molecular State of Loxoprofen in Acrylic Adhesive Patches Which Could Relate Transdermal Drug Permeability	2
The Inhibitory Effect of Adenylic Acid on the Bitterness of the Antibacterial Combination Drug Trimethoprim/Sulfamethoxazole	2
Spiromeroterpenoids from the Higher Plants	2
Stereoselective Synthesis of Aromatic Polyketide Prealnumycin	2
Elucidation of Complex Dynamic Intermolecular Interactions in Membranes	2
Synthesis of 2,8-Dioxabicyclo[3.3.1]nonane Derivatives and Their Neuroprotective Activities	2
Four Novel Pharmaceutical Cocrystals of Oxyresveratrol, Including a 2 : 3 Cocrystal with Betaine	2
Efficient and Environmentally Benign Oxidative Cleavage of Pyrrolidine-2-methanols to γ-Lactams Using 2-Iodobenzamide as a Catalyst and Oxone	2
4-Dimethylaminopyridine (DMAP), A Superior Mediator for Morita–Balylis–Hillman Reaction-Triggered Annulative Condensation of Salicylaldehydes and Acrylonitrile to Form 3-Cyano-2<i>H</i>-ch	2
A Structure–Activity Relationship Study of SNAIL1 Peptides as Inhibitors of Lysine-Specific Demethylase 1	2
Enhanced Physical Stability of L-Ascorbic Acid in an Ionic Liquid	2
Isolation of Natural Prodrug-Like Metabolite by Simulating Human Prodrug Activation in Filamentous Fungus	2
Structure Derivatization of IgG-Binding Peptides and Analysis of Their Secondary Structure by Circular Dichroism Spectroscopy	2
Semisynthesis and <i>in Vitro</i> Anti-cancer Effect of New Magnolol Derivatives on the Cell Proliferation, Apoptosis, Migration, and Invasion of Human Hepatocellular Carcinoma SMMC-7721 C	2
Enthalpy–Entropy Compensation in the Structure-Dependent Effect of Nonsteroidal Anti-inflammatory Drugs on the Aqueous Solubility of Diltiazem	2
Omphalines A–E: <i>ent</i>-Rosane-Type Diterpenoids from the Madagascar Endemic Plant, <i>Omphalea oppositifolia</i>	2
Experimental and DFT Studies of Intermolecular Interaction-Assisted Oxindole Cyclization Reaction of Di-<i>t</i>-butyl 2-Aminophenyl-2-methyl Malonate	2
Pharmaceutical Food Science: Search for Bio-Functional Molecules Obtained from Natural Resources to Prevent and Ameliorate Lifestyle Diseases	2
Copper-Catalyzed Aerobic C(<i>sp</i><sup>3</sup>)–H Oxidation of β-(Alkoxy)imino Carbonyl Compounds	2
A Data-Driven Approach to Predicting Tablet Properties after Accelerated Test Using Raw Material Property Database and Machine Learning	2
Structure–Signal Relationships of the <i>δ</i>-Opioid-Receptor (DOR)-Selective Agonist KNT-127—Part I: Impact of the Morphinan Skeleton on the G-Protein-Biased DOR Agonism	2
Preparation of Fine-Drugs Layered Spherical Particles with Good Micromeritic and Dissolution Properties through Ultra Cryo-Milling and Mechanical Powder Processing	2
Effects of Zinc Deficiency in Male Mice on Glucose Metabolism of Male Offspring	2
Development of Novel Methodology Using Diazo Compounds and Metal Catalysts	2
<sup>1</sup>H-NMR-Based Metabolomics for the Classification of the Roots of <i>Paeonia lactiflora</i>, a Constituent of Kampo Medicines	2
Molecular Transformation for Self-reproducing Vesicles and Underlying Analysis Methods	2
Carboxylative Cyclization of a Propargylic Amine with CO<sub>2</sub> Catalyzed by a Silica-Coated Magnetite	2
Rational Design of Amphipathic Antimicrobial Peptides with Alternating L-/D-Amino Acids That Form Helical Structures	2
Synthesis and Characterization of Hydroxyethylamino- and Pyridyl-Substituted 2-Vinyl Chromone Derivatives for Detection of Cerebral Abnormal Prion Protein Deposits	2
Electrochemical Analysis for Total Alkalinity of Water by the Measurement of Cathodic Prepeak of Quinone Caused by Surplus Acid	2
Construction of Biosensing System for Glycated Albumin Using an Electron Transfer Peptide-Modified Protein Probe	2
Selection of Short 5′-UTR of Chemically Synthesized mRNA to Improve Translation Efficiency	2
Secorubenine, a Monoterpenoid Indole Alkaloid Glycoside from <i>Adina rubescens</i>: Isolation, Structure Elucidation, and Enantioselective Total Synthesis	2
A Fluorescence Biosensor for Tyrosinase Activity Analysis Based on Silicon-Doped Carbon Quantum Dots	2
Facile Synthesis of 1,2-Disubstituted Benzimidazoles as Potent Cytotoxic Agents	2
Synthesis and Biological Evaluation of 2-Azolylmethylene-3-(2<i>H</i>)-benzofuranone Derivatives as Potent Monoamine Oxidases Inhibitors	2