OOIR: Observatory of International Research

Papers

(The H4-Index of Chemico-Biological Interactions is 43. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Editorial Board	815
Characterization of a novel porcine carbonyl reductase activated by glutathione: Relationship to carbonyl reductase 1, 3α/β-hydroxysteroid dehydrogenase and prostaglandin 9-ketoreductase	197
Anti-inflammatory effects of β-ionone-curcumin hybrid derivatives against ulcerative colitis	194
Low levels of endogenous cholinesterases support the choice of cows, sheep and goats for the transgenic expression of human butyrylcholinesterase in milk	163
Discovery and characterization of the flavonoids in Cortex Mori Radicis as naturally occurring inhibitors against intestinal nitroreductases	128
Editorial Board	113
HIF-1α: A potential therapeutic opportunity in renal fibrosis	108
Drug-drug interaction potentials of tucatinib inhibition of human UDP-glucuronosyltransferases	103
Air pollution-regulated E-cadherin mediates contact inhibition of proliferation via the hippo signaling pathways in emphysema	94
Chlorquinaldol inhibits the activation of nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing protein 3 inflammasome and ameliorates imiquimod-induced psoriasis-like	88
Exosomal miR-181a-2-3p derived from citreoviridin-treated hepatocytes activates hepatic stellate cells trough inducing mitochondrial calcium overload	83
Non-targeting siRNA-mediated responses are associated with apoptosis in chemotherapy-induced senescent skin cancer cells	80
Modeling of a near-attack conformation of oxime in phosphorylated acetylcholinesterase via a reactivation product, a phosphorylated oxime	77
In vitro and in vivo anti-inflammatory effects of 5-hydroxyconiferaldehyde via NF-κB, MAPK/AP-1, and Nrf2 modulation	76
Preconception paternal exposure to zearalenone impairs male fertility and IVF embryo survival in mice	74
Inflammatory response and DNA damage induced by dry tobacco exposure in rural workers: A study on complex mixtures and their health impacts	73
Alternative splicing affects synapses in the hippocampus of offspring after maternal fructose exposure during gestation and lactation	64
Selenium binding protein 1 protects renal tubular epithelial cells from ferroptosis by upregulating glutathione peroxidase 4	63
Retraction notice to “Quinone oxidoreductases in protection against myelogenous hyperplasia and benzene toxicity” [Chem. Biol. Interact. 153–154 (2005) 147–157]	61
Aspirin alleviates cisplatin-induced acute kidney injury through the AMPK-PGC-1α signaling pathway	60
Computational study to find the goat serum albumin (GSA) binding site as A-esterase	58
Copper homeostasis and its dysregulation in diseases: A focus on cuproptosis	58
Benzo[a]pyrene treatment modulates Nrf2/Keap1 axis and changes the metabolic profile in rat lung cancer	58
Thymol ameliorates ethanol-induced hepatotoxicity via regulating metabolism and autophagy	57
ER stress-enhanced HMGA2 plays an important role in Cr (VI)-induced glycolysis and inhibited oxidative phosphorylation by targeting the transcription of ATF4	56

Equol promotes osteogenic differentiation of hPDLSCs by inhibiting oxidative stress via IL1B/NF-κB/CXCL1 signaling axis	56
Perfluorooctanoic acid induces hepatocellular endoplasmic reticulum stress and mitochondrial-mediated apoptosis in vitro via endoplasmic reticulum-mitochondria communication	56
Honokiol inhibits interleukin-induced angiogenesis in the NSCLC microenvironment through the NF-κB signaling pathway	55
BjussuMP-II, a venom metalloproteinase, induces the release and cleavage of pro-inflammatory cytokines and disrupts human umbilical vein endothelial cells	55
F–53B triggers ovarian granulosa cell senescence and ovarian dysfunction by triggering mitochondrial dysfunction	53
Molecular mechanisms underlying the effects of beta-sitosterol on TGF-β1/Nrf2/SIRT1/p53-mediated signaling in the kidney of a high-fat diet and sucrose-induced type-2 diabetic rat	51
The influence of alkyl substitution on the in vitro metabolism and mutagenicity of benzo[a]pyrene	51
Antiviral potential of diminazene aceturate against SARS-CoV-2 proteases using computational and in vitro approaches	50
Upregulation of Nrf2 signaling and suppression of ferroptosis and NF-κB pathway by leonurine attenuate iron overload-induced hepatotoxicity	50
Inhibition of AT1R/IP3/IP3R-mediated Ca2+ release protects against calcium oxalate crystals-induced renal oxidative stress	48
Wnt/β-catenin antagonist pyrvinium rescues high dose isoproterenol induced cardiotoxicity in rats: Biochemical and immunohistological evidences	48
Recalling the reported toxicity assessment of deoxynivalenol, mitigating strategies and its toxicity mechanisms: Comprehensive review	47
HO-1 activation contributes to cadmium-induced ferroptosis in renal tubular epithelial cells via increasing the labile iron pool and promoting mitochondrial ROS generation	47
Aristolochic acid I abnormally activates the wnt7b/β-catenin signaling pathway and affects the repair of renal tubules	46
Gold(I) N-heterocyclic carbene complexes show strong proapoptotic, antioxidant and anti-inflammatory effects in A2780 and endothelial cells	45
Arsenic exposure accelerates type 1 diabetes mellitus progression via pyroptosis pathway in mice	44
Editorial Board	44
Involvement of esterases in the pulmonary metabolism of beclomethasone dipropionate and the potential influence of cannabis use	44
The JNK/P38 signalling pathway activated by testin protects the intestinal epithelial barrier against Crohn's disease-like colitis	43
Editorial Board	43
Particle-induced osteolysis is mediated by endoplasmic reticulum stress-associated osteoblast apoptosis	43