OOIR: Observatory of International Research

Papers

(The H4-Index of Chemico-Biological Interactions is 39. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Platinum as both a drug and its modulator – Do platinum nanoparticles influence cisplatin activity?	513
The modulator action of thiamine against pentylenetetrazole-induced seizures, apoptosis, nitric oxide, and oxidative stress in rats and SH-SY5Y neuronal cell line	176
Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans	139
Fatty acid binding protein 4 regulates doxorubicin-induced renal injury via mediating lipid metabolism and apoptosis	131
Modulatory roles of capsaicin on thermogenesis in C2C12 myoblasts and the skeletal muscle of mice	129
In vitro and in vivo anti-inflammatory effects of 5-hydroxyconiferaldehyde via NF-κB, MAPK/AP-1, and Nrf2 modulation	126
Prophylaxis by a reversible cholinesterase inhibitor and the NMDA receptor antagonist treatment as combinatorial countermeasure against nerve agent poisoning in mice model	122
Equol promotes osteogenic differentiation of hPDLSCs by inhibiting oxidative stress via IL1B/NF-κB/CXCL1 signaling axis	102
Targeting eosinophils in chronic respiratory diseases using nanotechnology-based drug delivery	77
Alpha-tubulin relocalization is involved in calcium oxalate-induced tight junction disruption in renal epithelial cells	76
ER stress-enhanced HMGA2 plays an important role in Cr (VI)-induced glycolysis and inhibited oxidative phosphorylation by targeting the transcription of ATF4	69
Inhibitory effect of imperatorin on dabrafenib metabolism in vitro and in vivo	67
α-Lipoic acid improves mitochondrial biogenesis and dynamics by enhancing antioxidant and inhibiting Wnt/Ca2+ pathway to relieve fluoride-induced hepatotoxic injury	66
Bisphenol A and genistein have opposite effects on adult chicken ovary by acting on ERα/Nrf2-Keap1-signaling pathway	63
Selenium binding protein 1 protects renal tubular epithelial cells from ferroptosis by upregulating glutathione peroxidase 4	59
Molecular mechanisms underlying the effects of beta-sitosterol on TGF-β1/Nrf2/SIRT1/p53-mediated signaling in the kidney of a high-fat diet and sucrose-induced type-2 diabetic rat	59
Advances in designing of polymeric micelles for biomedical application in brain related diseases	58
Antiviral potential of diminazene aceturate against SARS-CoV-2 proteases using computational and in vitro approaches	56
Paraoxonase 1 activity in patients with Alzheimer disease: Systematic review and meta-analysis	53
Inhibition of AT1R/IP3/IP3R-mediated Ca2+ release protects against calcium oxalate crystals-induced renal oxidative stress	53
Research progress of small-molecule drugs in targeting telomerase in human cancer and aging	52
Matrine disrupts Nrf2/GPX4 antioxidant system and promotes hepatocyte ferroptosis	50
Retraction notice to “Agonism of GPR120 prevents ox-LDL-induced attachment of monocytes to endothelial cells” [Chem. Biol. Interact. 316 (2020) 108916]	49
Retraction notice to “Zinc moderates circular RNA CircFOXP1 expression in order to regulate ferroptosis during lung adenocarcinoma” [Chem. Biol. Interact. 352 (25 January 2022) 109760]	49
Retraction notice to “Potential of β-elemene induced ferroptosis through Pole2-mediated p53 and PI3K/AKT signaling in lung cancer cells” [Chem. Biol. Interact. 365 (25 September 2022) 110088]	48

Metformin promotes the survival of random skin flaps via the activation of Nrf2/HO-1 signaling	48
Galium aparine L. protects against acetaminophen-induced hepatotoxicity in rats	48
Potential food-drug interaction risk of thymoquinone with warfarin	46
Green tea actions on miRNAs expression – An update	46
Toxicity of nanomixtures to human macrophages: Joint action of silver and polystyrene nanoparticles	46
Effects of myricetin and quercetin on ticagrelor metabolism and the underlying mechanism	44
The role of ALDH1A1 in glioblastoma proliferation and invasion	43
Solid lipid nanoparticle: A potent vehicle of the kaempferol for brain delivery through the blood-brain barrier in the focal cerebral ischemic rat	43
The influence of alkyl substitution on the in vitro metabolism and mutagenicity of benzo[a]pyrene	43
The role of cyclin-dependent kinase inhibitor 3 in the proliferation and migration of renal cell carcinoma	42
Re-appraising the role of flavonols, flavones and flavonones on osteoblasts and osteoclasts- A review on its molecular mode of action	42
Exploring Asphodelus microcarpus as a source of xanthine oxidase inhibitors: Insights from in silico and in vitro studies	41
Myrsinoic acid B from Myrsine coriacea reverses depressive-like behavior and brain oxidative stress in streptozotocin-diabetic rats	39
Gypenoside XLIX alleviates intestinal injury by inhibiting sepsis-induced inflammation, oxidative stress, apoptosis, and autophagy	39
Cisatracurium regulates the CXCR4/let-7a-5p axis to inhibit colorectal cancer progression by suppressing TGF-β/SMAD2/3 signalling	39