Chemico-Biological Interactions

Article	Citations
Platinum as both a drug and its modulator – Do platinum nanoparticles influence cisplatin activity?	513
The modulator action of thiamine against pentylenetetrazole-induced seizures, apoptosis, nitric oxide, and oxidative stress in rats and SH-SY5Y neuronal cell line	176
Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans	139
Fatty acid binding protein 4 regulates doxorubicin-induced renal injury via mediating lipid metabolism and apoptosis	131
Modulatory roles of capsaicin on thermogenesis in C2C12 myoblasts and the skeletal muscle of mice	129
In vitro and in vivo anti-inflammatory effects of 5-hydroxyconiferaldehyde via NF-κB, MAPK/AP-1, and Nrf2 modulation	126
Prophylaxis by a reversible cholinesterase inhibitor and the NMDA receptor antagonist treatment as combinatorial countermeasure against nerve agent poisoning in mice model	122
Equol promotes osteogenic differentiation of hPDLSCs by inhibiting oxidative stress via IL1B/NF-κB/CXCL1 signaling axis	102
Targeting eosinophils in chronic respiratory diseases using nanotechnology-based drug delivery	77
Alpha-tubulin relocalization is involved in calcium oxalate-induced tight junction disruption in renal epithelial cells	76
ER stress-enhanced HMGA2 plays an important role in Cr (VI)-induced glycolysis and inhibited oxidative phosphorylation by targeting the transcription of ATF4	69
Inhibitory effect of imperatorin on dabrafenib metabolism in vitro and in vivo	67
α-Lipoic acid improves mitochondrial biogenesis and dynamics by enhancing antioxidant and inhibiting Wnt/Ca2+ pathway to relieve fluoride-induced hepatotoxic injury	66
Bisphenol A and genistein have opposite effects on adult chicken ovary by acting on ERα/Nrf2-Keap1-signaling pathway	63
Selenium binding protein 1 protects renal tubular epithelial cells from ferroptosis by upregulating glutathione peroxidase 4	59
Molecular mechanisms underlying the effects of beta-sitosterol on TGF-β1/Nrf2/SIRT1/p53-mediated signaling in the kidney of a high-fat diet and sucrose-induced type-2 diabetic rat	59
Advances in designing of polymeric micelles for biomedical application in brain related diseases	58
Antiviral potential of diminazene aceturate against SARS-CoV-2 proteases using computational and in vitro approaches	56
Inhibition of AT1R/IP3/IP3R-mediated Ca2+ release protects against calcium oxalate crystals-induced renal oxidative stress	53
Paraoxonase 1 activity in patients with Alzheimer disease: Systematic review and meta-analysis	53
Research progress of small-molecule drugs in targeting telomerase in human cancer and aging	52
Matrine disrupts Nrf2/GPX4 antioxidant system and promotes hepatocyte ferroptosis	50
Retraction notice to “Zinc moderates circular RNA CircFOXP1 expression in order to regulate ferroptosis during lung adenocarcinoma” [Chem. Biol. Interact. 352 (25 January 2022) 109760]	49
Retraction notice to “Agonism of GPR120 prevents ox-LDL-induced attachment of monocytes to endothelial cells” [Chem. Biol. Interact. 316 (2020) 108916]	49
Galium aparine L. protects against acetaminophen-induced hepatotoxicity in rats	48

Retraction notice to “Potential of β-elemene induced ferroptosis through Pole2-mediated p53 and PI3K/AKT signaling in lung cancer cells” [Chem. Biol. Interact. 365 (25 September 2022) 110088]	48
Metformin promotes the survival of random skin flaps via the activation of Nrf2/HO-1 signaling	48
Toxicity of nanomixtures to human macrophages: Joint action of silver and polystyrene nanoparticles	46
Potential food-drug interaction risk of thymoquinone with warfarin	46
Green tea actions on miRNAs expression – An update	46
Effects of myricetin and quercetin on ticagrelor metabolism and the underlying mechanism	44
The influence of alkyl substitution on the in vitro metabolism and mutagenicity of benzo[a]pyrene	43
The role of ALDH1A1 in glioblastoma proliferation and invasion	43
Solid lipid nanoparticle: A potent vehicle of the kaempferol for brain delivery through the blood-brain barrier in the focal cerebral ischemic rat	43
Re-appraising the role of flavonols, flavones and flavonones on osteoblasts and osteoclasts- A review on its molecular mode of action	42
The role of cyclin-dependent kinase inhibitor 3 in the proliferation and migration of renal cell carcinoma	42
Exploring Asphodelus microcarpus as a source of xanthine oxidase inhibitors: Insights from in silico and in vitro studies	41
Gypenoside XLIX alleviates intestinal injury by inhibiting sepsis-induced inflammation, oxidative stress, apoptosis, and autophagy	39
Cisatracurium regulates the CXCR4/let-7a-5p axis to inhibit colorectal cancer progression by suppressing TGF-β/SMAD2/3 signalling	39
Myrsinoic acid B from Myrsine coriacea reverses depressive-like behavior and brain oxidative stress in streptozotocin-diabetic rats	39
Molecular mechanisms underlying chemopreventive potential of butein: Current trends and future perspectives	38
Sodium butyrate ameliorates the impairment of synaptic plasticity by inhibiting the neuroinflammation in 5XFAD mice	38
Editorial Board	38
Upregulation of Nrf2 signaling and suppression of ferroptosis and NF-κB pathway by leonurine attenuate iron overload-induced hepatotoxicity	37
Enantioselective toxic effects of the novel chiral antifungal agrochemical penthiopyrad in the early life stage of zebrafish (Danio rerio)	37
Anticancer effects of oleanolic acid on human melanoma cells	37
Sodium aescinate induces renal toxicity by promoting Nrf2/GPX4-mediated ferroptosis	37
Cadmium induces triglyceride levels via microsomal triglyceride transfer protein (MTTP) accumulation caused by lysosomal deacidification regulated by endoplasmic reticulum (ER) Ca2+ homeostasis	37
Tuberostemonine alleviates high-fat diet-induced obesity and hepatic steatosis by increasing energy consumption	36
Synthesis of biocompatible nanocrystalline cellulose against folate receptors as a novel carrier for targeted delivery of doxorubicin	35
Testing of the inhibitory effects of loratadine and desloratadine on SARS-CoV-2 spike pseudotyped virus viropexis	35
Perfluorooctanoic acid induces hepatocellular endoplasmic reticulum stress and mitochondrial-mediated apoptosis in vitro via endoplasmic reticulum-mitochondria communication	35
The disruption of blood-brain barrier induced by long-term arsenic exposure is associated with the increase of MMP-9 and MMP-2: The characteristics are similar to those caused by senescence	34
Effects of whole-life exposure to low-dose cadmium with post-weaning high-fat diet on offspring testes in a male mouse model	34
Modulation of the miR-122/Sirt-6/ACE2 axis on experimentally-induced myocardial infarction	33
Natural soluble epoxide hydrolase inhibitors from Inula britanica and their potential interactions with soluble epoxide hydrolase: Insight from inhibition kinetics and molecular dynamics	33
Probing the anticancer activities of facial trioxorhenium and tricarbonylrhenium compounds with heterocyclic ligands	32
SERS spectroscopy as a tool for the study of thiopurine drug pharmacokinetics in a model of human B leukemia cells	32
Mode of action assessment for propylene dichloride as a human carcinogen	32
(m-CF3-PhSe)2 benefits against anxiety-like phenotype associated with synaptic plasticity impairment and NMDAR-mediated neurotoxicity in young mice exposed to a lifestyle model	32
Editorial Board	31
Molecular determinants of the response of cancer cells towards geldanamycin and its derivatives	31
Editorial Board	31
An in vitro alveolar model allows for the rapid assessment of chemical respiratory sensitization with modifiable biomarker endpoints	31
Editorial Board	31
Molybdenum and/or cadmium induce NLRP3 inflammasome production by causing mitochondria-associated endoplasmic reticulum membrane dysfunction in sheep hepatocytes	31
Computational study to find the goat serum albumin (GSA) binding site as A-esterase	30
Discovery of a novel jellyfish venom metalloproteinase inhibitor from secondary metabolites isolated from jellyfish-derived fungus Aspergillus versicolor SmT07	30
Emerging applications and prospects of NFκB decoy oligodeoxynucleotides in managing respiratory diseases	29
Comments on “Dihydroartemisinin induces pyroptosis by promoting the AIM2/caspase-3/DFNA5 axis in breast cancer cells."	29
Chromenopyrimidinone exhibit antitumor effects through inhibition of CAP1 (Adenylyl cyclase-associated protein 1) expression in hepatocellular carcinoma	28
Editorial Board	28
Epinephrine facilitates the growth of T cell lymphoma by altering cell proliferation, apoptosis, and glucose metabolism	28
Editorial Board	28
Regulatory effects of non-steroidal anti-inflammatory drugs on cardiac ion channels Nav1.5 and Kv11.1	28

Inactivation of ricin by constituents present in a skin decontamination lotion	28
AhR regulates VEGF expression by promoting STAT1 transcriptional activity, thereby affecting endothelial angiogenesis in acute limb ischemia	28
Editorial Board	28
Editorial Board	27
Novel indole-guanidine hybrids as potential anticancer agents: Design, synthesis and biological evaluation	27
Editorial Board	27
SIRT6 activates PPARα to improve doxorubicin-induced myocardial cell aging and damage	27
Inhibition of AKR1Cs by liquiritigenin and the structural basis	27
Editorial Board	26
Icaritin activates p53 and inhibits aerobic glycolysis in liver cancer cells	26
A photoactivatable chemotherapeutic Ru(II) complex bearing bathocuproine ligand efficiently induces cell death in human malignant melanoma cells through a multi-mechanistic pathway	26
Biphasic effect of limonene on contraction of isolated rat aorta	26
Sorafenib-induced cardiovascular toxicity: A cause for concern	26
Catalpol ameliorates endothelial dysfunction and inflammation in diabetic nephropathy via suppression of RAGE/RhoA/ROCK signaling pathway	26
Harnessing the therapeutic potential of fisetin and its nanoparticles: Journey so far and road ahead	26
The selective activator protein-1 inhibitor T-5224 regulates the IRF4/MYC axis and exerts cooperative antimyeloma activity with bortezomib	26
Investigation of the relaxing effect of a camphor nanoemulsion on rat isolated trachea	26
Selenite induced breast cancer MCF7 cells apoptosis through endoplasmic reticulum stress and oxidative stress pathway	25
Oleanolic acid promotes liver regeneration after partial hepatectomy via regulating pregnane X receptor signaling pathway in mice	25
Lauric acid alleviates deoxynivalenol-induced intestinal stem cell damage by potentiating the Akt/mTORC1/S6K1 signaling axis	25
Role of phytoconstituents in the management of COVID-19	25
Small-molecule MX-C2/3 suppresses non-small cell lung cancer progression via p53 activation	25
Arecoline induces cardiotoxicity by upregulating and activating cardiac hypertrophy-related pathways in Sprague–Dawley rats	25
Cryoprotective isoliquiritigenin-zein phosphatidylcholine nanoparticles inhibits breast cancer-bone metastasis by targeting JAK-STAT signaling pathways	25
Morusin inhibits breast cancer-induced osteolysis by decreasing phosphatidylinositol 3-kinase (PI3K)-mTOR signalling	25
Oxymatrine inhibits migration and invasion of esophageal squamous cell carcinoma cell lines via the MEK1/ERK/β-catenin pathway	25
Synthesis of glucosamine-selenium compound and evaluation of its oral toxicity and in vitro anti-hepatitis B virus activity	25
Guttiferones: An insight into occurrence, biosynthesis, and their broad spectrum of pharmacological activities	25
Theaflavin-3-gallate, a natural antagonist for Hsp90: In-silico and in-vitro approach	24
Cellular responses following ex vivo lung exposure to the nerve agent VX – Potential for additional treatment targets?	24
Comparisons of the immunological landscape of COVID-19 patients based on sex and disease severity by multi-omics analysis	24
Fibroblast activation protein alpha: Comprehensive detection methods for drug target and tumor marker	24
Evi1 involved in benzene-induced haematotoxicity via modulation of PI3K/mTOR pathway and negative regulation Serpinb2	24
Antitumor activity, DNA and BSA interactions of novel copper(II) complexes with 3,4-dihydro-2(1H)-quinoxalinones	24
In silico and in vitro antileishmanial effects of gamma-terpinene: Multifunctional modes of action	23
γ-Glutamylcysteine attenuates amyloid-β oligomers-induced neuroinflammation in microglia via blocking NF-κB signaling pathway	23
Exosomal miR-181a-2-3p derived from citreoviridin-treated hepatocytes activates hepatic stellate cells trough inducing mitochondrial calcium overload	23
TRPC6 is altered in COVID-19 pneumonia	23
Proteomic profiling reveals an association between ALDH and oxidative phosphorylation and DNA damage repair pathways in human colon adenocarcinoma stem cells	22
Air pollution-regulated E-cadherin mediates contact inhibition of proliferation via the hippo signaling pathways in emphysema	22
Physiological oxygen and co-culture with human fibroblasts facilitate in vivo-like properties in human renal proximal tubular epithelial cells	22
Molecular interactions of hesperidin with DMPC/cholesterol bilayers	22
Anti-inflammatory effects of β-ionone-curcumin hybrid derivatives against ulcerative colitis	22
A new reduced chalcone-derivative affects the membrane permeability and electric potential of multidrug-resistant Enterococcus faecalis	22
d-ribose-mediated glycation of fibrinogen: Role in the induction of adaptive immune response	21
Induction of cardiotoxicity in zebrafish embryos by 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene through the JAK-STAT and NOTCH signaling pathways	21
Kaempferol alleviates the inflammatory response and stabilizes the pulmonary vascular endothelial barrier in LPS-induced sepsis through regulating the SphK1/S1P signaling pathway	21
Chemicals of environmental concern as inhibitors of human placental 3β-hydroxysteroid dehydrogenase 1 and aromatase: Screening and docking analysis	21
Role of Wnt/β-catenin signaling pathway in ameloblast differentiation in relevance to dental fluorosis	21
Non-targeting siRNA-mediated responses are associated with apoptosis in chemotherapy-induced senescent skin cancer cells	21
Long-term copper exposure caused hepatocytes autophagy in broiler via miR-455-3p-OXSR1 axis	21
Low levels of endogenous cholinesterases support the choice of cows, sheep and goats for the transgenic expression of human butyrylcholinesterase in milk	20
Indole alkaloids from marine resources: Understandings from therapeutic point of view to treat cancers	20
Honokiol inhibits interleukin-induced angiogenesis in the NSCLC microenvironment through the NF-κB signaling pathway	20
Thymol ameliorates ethanol-induced hepatotoxicity via regulating metabolism and autophagy	20
Hydroxylated polymethoxyflavones reduce the activity of pancreatic lipase, inhibit adipogenesis and enhance lipolysis in 3T3-L1 mouse embryonic fibroblast cells	20
Protective effects of phosphocreatine on human vascular endothelial cells against hydrogen peroxide-induced apoptosis and in the hyperlipidemic rat model	20
Gut microbiota contribute to Methamphetamine-induced cardiotoxicity in mouse model	20
Inflammation- and cancer-related microRNAs in rat renal cortex after subchronic exposure to fluoride	20
In-Silico molecular screening of natural compounds as a potential therapeutic inhibitor for Methicillin-resistant Staphylococcus aureus inhibition	20
Alternative splicing affects synapses in the hippocampus of offspring after maternal fructose exposure during gestation and lactation	20
Detection of a glutathionyl-carbonylated group (GS–CO–) on D-dopachrome tautomerase with preferential binding of GS–CO– to MIF proteins in rat livers damaged by carbon tetrachloride	20
Comprehensive analysis of cellular estrogen signaling in representative estrogen receptor ligands	20
ERO1α primes the ryanodine receptor to respond to arsenite with concentration dependent Ca2+ release sequentially triggering two different mechanisms of ROS formation	20
Trimetazidine alleviates paclitaxel-induced peripheral neuropathy through modulation of TLR4/p38/NF-κB and klotho protein expression	20
Intestinal homeostasis disruption in mice chronically exposed to arsenite-contaminated drinking water	20
7, 8-Dihydroxy-4-methyl coumarin alleviates cholestasis via activation of the Farnesoid X receptor in vitro and in vivo	20
Drug-drug interaction potentials of tucatinib inhibition of human UDP-glucuronosyltransferases	20
In‐vitro antiviral screening of some thiopyranothiazoles	19
Cyclophosphamide reduces gene transcriptional activity and embryo in vitro development by inhibiting NF-κB expression through decreasing AcH4K12	19
Mitigation of lens opacification by a functional food in a diabetic rodent model	19
Targeting PKD2 aggravates ferritinophagy-mediated ferroptosis via promoting autophagosome-lysosome fusion and enhances efficacy of carboplatin in lung adenocarcinoma	19
Neuroprotective role of vitamin B12 in streptozotocin-induced type 1 diabetic rats	19
Recalling the reported toxicity assessment of deoxynivalenol, mitigating strategies and its toxicity mechanisms: Comprehensive review	19
Interfering TRIB3 protects the blood brain barrier through PI3K/Akt pathway to alleviate cerebral ischemia-reperfusion injury in diabetes mellitus mice	19
Inhibition of sphingosine kinase 1 attenuates LPS-induced acute lung injury by suppressing endothelial cell pyroptosis	19
Oleanolic acid induces HCT116 colon cancer cell death through the p38/FOXO3a/Sirt6 pathway	18
Discovery and characterization of the flavonoids in Cortex Mori Radicis as naturally occurring inhibitors against intestinal nitroreductases	18
Benzo[a]pyrene treatment modulates Nrf2/Keap1 axis and changes the metabolic profile in rat lung cancer	18
Muller letter reveals scientific scandal that discredits evidence used to support LNT	18

Nickel induces mitochondrial damage in renal cells in vitro and in vivo through its effects on mitochondrial biogenesis, fusion, and fission	18
Assessments of carbon nanotubes toxicities in zebrafish larvae using multiple physiological and molecular endpoints	18
Development of a conduit of PLGA-gelatin aligned nanofibers produced by electrospinning for peripheral nerve regeneration	18
Hormetic effects of EGC and EGCG on CES1 activity and its rescue from oxidative stress in rat liver S9	18
Corrigendum to “Discovery and characterization of the flavonoids in Cortex Mori Radicis as naturally occurring inhibitors against intestinal nitroreductases” [Chem. Biol. Interact. 368 (2022) 110222]	18
Protective effect of eicosapentaenoic acid against estradiol valerate-induced endometrial hyperplasia via modulation of NF-κB/HIF-1α/VEGF signaling pathway in rats	18
Taurine induces hormesis in multiple biological models: May have transformative implications for overall societal health	18
BjussuMP-II, a venom metalloproteinase, induces the release and cleavage of pro-inflammatory cytokines and disrupts human umbilical vein endothelial cells	18
Urea cycle promotion via ammonia-upregulated CPS1 is involved in arsenite-induced pulmonary fibrosis through enhancing collagen synthesis	18
Casticin ameliorates osteoarthritic cartilage damage in rats through PI3K/AKT/HIF-1α signaling	18
Modeling of a near-attack conformation of oxime in phosphorylated acetylcholinesterase via a reactivation product, a phosphorylated oxime	18
Malvidin promotes PGC-1α/Nrf2 signaling to attenuate the inflammatory response and restore mitochondrial activity in septic acute kidney injury	18
Characterization of a novel porcine carbonyl reductase activated by glutathione: Relationship to carbonyl reductase 1, 3α/β-hydroxysteroid dehydrogenase and prostaglandin 9-ketoreductase	18
A 50-gene biomarker identifies estrogen receptor-modulating chemicals in a microarray compendium	18
Different concentrations of betaxolol switch cell fate between necroptosis, apoptosis, and senescence in human corneal stromal cells	18
Fecal microbiota transplantation and short-chain fatty acids improve learning and memory in fluorosis mice by BDNF-PI3K/AKT pathway	17
Integrated analysis reveals the immunotoxicity mechanism of BPs on human lymphocytes	17
TRP channels in COVID-19 disease: Potential targets for prevention and treatment	17
Von Willebrand factor: A key glycoprotein involved in thrombo-inflammatory complications of COVID-19	17
Ursonic acid from Artemisia montana exerts anti-diabetic effects through anti-glycating properties, and by inhibiting PTP1B and activating the PI3K/Akt signaling pathway in insulin-resistant C2C12 cel	17
Chlorpyrifos oxon crosslinking of amyloid beta 42 peptides is a new route for generation of self-aggregating amyloidogenic oligomers that promote Alzheimer's disease	17
HO-1 activation contributes to cadmium-induced ferroptosis in renal tubular epithelial cells via increasing the labile iron pool and promoting mitochondrial ROS generation	17
Vascular endothelial effects of dibutyl phthalate: In vitro and in vivo evidence	17
Icariin inhibits hypertrophy by regulation of GPER1 and CaMKII/HDAC4/MEF2C signaling crosstalk in ovariectomized mice	17
Effects of the antitumor drugs adagrasib and asciminib on apixaban metabolism in vitro and in vivo	17
Discovery of mycotoxin alternariol as a potential lead compound targeting xanthine oxidase	17
Hydroxygenkwanin suppresses peritoneal metastasis in colorectal cancer by modulating tumor-associated macrophages polarization	17
Thalidomide suppresses angiogenesis and immune evasion via lncRNA FGD5-AS1/miR-454–3p/ZEB1 axis-mediated VEGFA expression and PD-1/PD-L1 checkpoint in NSCLC	17
Autophagy aggravates multi-walled carbon nanotube-induced ferroptosis by suppressing PGC-1 dependent-mitochondrial biogenesis in lung epithelial cells	17
Bis-(3-amino-2-pyridine) diselenide improves psychiatric disorders –atopic dermatitis comorbidity by regulating inflammatory and oxidative status in mice	17
Human cell-based estrogen receptor beta dimerization assay	17
Lipopolysaccharide modification enhances the inhibitory effect of clodronate liposomes on hepatic fibrosis by depletion of macrophages and hepatic stellate cells	16
Paracetamol suppresses neutrophilic oxygen radicals through competitive inhibition and scavenging	16
Risk prediction of drug-drug interaction potential of phenytoin and miconazole topical formulations	16
Synthesis, anticancer activity and mechanism of action of new phthalimido-1,3-thiazole derivatives	16
The assessment of the phototoxic potential of drugs forming complexes with melanin - Screening in vitro studies using normal skin cells with varying pigmentation irradiated by a sunlight simulator	16
Do the hormetic effects of chlorogenic acid mediate some of the beneficial effects of coffee?	16
Behavioral and neurochemical effects in mice after one-generation exposure to low doses of manganese: Focus on offspring development	16
In vitro evaluation of the toxicity mechanisms of two functionalized reduced graphene oxide derivatives	16
Neuroprotective thiourea derivative uncouples mitochondria and exerts weak protonophoric action on lipid membranes	16
Cytotoxic and radical activities of metal-organic framework modified with iron oxide: Biological and physico-chemical analyses	16
Urolithin A attenuates Doxorubicin-induced cardiotoxicity by enhancing PINK1-regulated mitophagy via Ambra1	16
Hemocompatible L-Type amino acid transporter 1 (LAT1)-Utilizing prodrugs of perforin inhibitors can accumulate into the pancreas and alleviate inflammation-induced apoptosis	16
Geraniol isolated from lemon grass to mitigate doxorubicin-induced cardiotoxicity through Nrf2 and NF-κB signaling	15
Baicalein ameliorates polymyxin B-induced acute renal injury by inhibiting ferroptosis via regulation of SIRT1/p53 acetylation	15
Doping gadolinium versus lanthanum into hydroxyapatite particles for better biocompatibility in bone marrow stem cells	15
Reduction of photoswitched, nitrogen bridged N-acetyl diazocines limits inhibition of 17βHSD3 activity in transfected human embryonic kidney 293 cells	15
Corrigendum to “Dihydroartemisinin mediating PKM2-caspase-8/3-GSDME axis for pyroptosis in esophageal squamous cell carcinoma” [Chem. Biol. Interact. 350 (2021) 109704]	15
Harnessing the dual role of polysaccharides in treating gastrointestinal diseases: As therapeutics and polymers for drug delivery	15
Homogentisic acid, a main phenolic constituent of strawberry tree honey, protects human peripheral blood lymphocytes against irinotecan-induced cytogenetic damage in vitro	15
Glycerophospholipid metabolic disorders and gender difference of cantharidin-induced hepatotoxicity in rats: Lipidomics and MALDI mass spectrometry imaging analysis	15
Vasorelaxant effect of 5,7,4′- Trihydroxyflavanone (Naringenin) via endothelium dependent, potassium and calcium channels in Sprague Dawley rats: Aortic ring model	15
Control of ER-positive breast cancer by ERα expression inhibition, apoptosis induction, cell cycle arrest using semisynthetic isoeugenol derivatives	15
Novel trajectories of the NK1R antagonist aprepitant in rotenone-induced Parkinsonism-like symptoms in rats: Involvement of ERK5/KLF4/p62/Nrf2 signaling axis	15
Plant defence mechanisms against mycotoxin Fumonisin B1	15
Nanoparticle formulations: A smart era of advanced treatment with nanotoxicological imprints on the human body	15
Corrigendum to “Adaptive regulations of Nrf2 alleviates silver nanoparticles-induced oxidative stress-related liver cells injury” [Chemico-Biol. Interact. 369 (2023) 110287]	15
Cytotoxic activity and influence on acetylcholinesterase of series dinuclear platinum(II) complexes with aromatic nitrogen-containing heterocyclic bridging ligands: Insights in the mechanisms of actio	15
HNF4A as a potential target of PFOA and PFOS leading to hepatic steatosis: Integrated molecular docking, molecular dynamic and transcriptomic analyses	15
Assessment of doxorubicin toxicity using human cardiac organoids: A novel model for evaluating drug cardiotoxicity	15
α-Hederin induces human colorectal cancer cells apoptosis through disturbing protein homeostasis	14
Wnt/β-catenin antagonist pyrvinium rescues high dose isoproterenol induced cardiotoxicity in rats: Biochemical and immunohistological evidences	14
Modulating SIRT1, Nrf2, and NF-κB signaling pathways by bergenin ameliorates the cadmium-induced nephrotoxicity in rats	14
Methylglyoxal induces cardiac dysfunction through mechanisms involving altered intracellular calcium handling in the rat heart	14
Inhibition of ER stress using tauroursodeoxycholic acid rescues obesity-evoked cardiac remodeling and contractile anomalies through regulation of ferroptosis	14
Honokiol and its analogues as anticancer compounds: Current mechanistic insights and structure-activity relationship	14
Review: Organophosphorus toxicants, in addition to inhibiting acetylcholinesterase activity, make covalent adducts on multiple proteins and promote protein crosslinking into high molecular weight aggr	14
Isovitexin prevents DSS-induced colitis through inhibiting inflammation and preserving intestinal barrier integrity through activating AhR	14
Salvianolic acid A attenuates non-alcoholic fatty liver disease by regulating the AMPK-IGFBP1 pathway	14
STIP1 knockdown suppresses colorectal cancer cell proliferation, migration and invasion by inhibiting STAT3 pathway	14
No-observed-adverse-effect-level (NOAEL) assessment as an optimized dose of cholinesterase reactivators for the treatment of exposure to warfare nerve agents in mice	14
2,3,5,4′-Tetrahydroxy stilbene-2-Ο-β-D-glucoside, a mechanism-based inactivator of CYP2C19 and CYP3A4, potentiates hepatic protein adduction and hepatotoxicity induced by emodin in vivo	14
The SPATA2/CYLD pathway contributes to doxorubicin-induced cardiomyocyte ferroptosis via enhancing ferritinophagy	14
Arsenic trioxide-induced autophagy affected the antioxidant capacity and apoptosis rate of chicken hepatocytes	14
Biochemical interaction of pyrvinium in gentamicin-induced acute kidney injury by modulating calcium dyshomeostasis and mitochondrial dysfunction	14
Empagliflozin alleviates endoplasmic reticulum stress and augments autophagy in rotenone-induced Parkinson's disease in rats: Targeting the GRP78/PERK/eIF2α/CHOP pathway and miR-211-5p	14
Ferroptosis is involved in the benzene-induced hematotoxicity in mice via iron metabolism, oxidative stress and NRF2 signaling pathway	14
Berberine hydrochloride ameliorates PM2.5-induced pulmonary fibrosis in mice through inhibiting oxidative stress and inflammatory	14
Ligand-independent activation of AhR by hydroquinone mediates benzene-induced hematopoietic toxicity	14
Dipyridophenazine iridium(III) complex as a phototoxic cancer stem cell selective, mitochondria targeting agent	14
Resveratrol inhibits glioblastoma cells and chemoresistance progression through blockade P-glycoprotein and targeting AKT/PTEN signaling pathway	14
Aureusidin ameliorates 6-OHDA-induced neurotoxicity via activating Nrf2/HO-1 signaling pathway and preventing mitochondria-dependent apoptosis pathway in SH-SY5Y cells and Caenorhabditis elegans	14
Nanocarrier design–function relationship: The prodigious role of properties in regulating biocompatibility for drug delivery applications	14
Neuropathology and cholinesterase expression in the brains of octogenarians and older	14
PINK1/Parkin-mediated mitophagy is activated to protect against AFB1-induced kidney damage in mice	13
Effects of two commonly used antidepressants amitriptyline and fluoxetine on the pharmacokinetics of abrocitinib in rats	13
Baicalein ameliorates cerebral ischemia-reperfusion injury by inhibiting ferroptosis via regulating GPX4/ACSL4/ACSL3 axis	13
Metabolism-dependent inhibition of CYP2E1 by isoniazid, a mediator of idiosyncratic liver injury	13
Urolithin D: A promising metabolite of ellagitannin in combatting oxidative stress	13
Coptisine-mediated downregulation of E2F7 induces G2/M phase arrest in hepatocellular carcinoma cells through inhibition of E2F4/NFYA/NFYB transcription factors	13
Diosgenin attenuates nonalcoholic fatty liver disease through mTOR-mediated inhibition of lipid accumulation and inflammation	13
Warning on the inhalation of silica nanoparticles: Experimental evidence for its easy passage through the air-blood barrier, resulting in systemic distribution and pathological injuries	13
The mechanism of interaction between tri-para-cresyl phosphate and human serum protein: A multispectroscopic and in-silico study	13
Sevoflurane enhances autophagy via Rac1 to attenuate lung ischaemia‒reperfusion injury	13
Perspectives on using bacteriophages in biogerontology research and interventions	13