OOIR: Observatory of International Research

Papers

(The TQCC of Chemistry of Heterocyclic Compounds is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Imidazol-5-one-based donor–acceptor cyclopropanes in reaction with C=S dipolarophiles	48
Pyridine-2-selanyl chloride in the synthesis of condensed heterocycles (microreview)	46
PIDA-mediated C–N coupling cyclization for the synthesis of 3-aryl-1H-indazoles	40
An intramolecular Diels–Alder reaction in the synthesis of N-aroyl-3a,6-epoxyisoindole-2-carbothioamides	21
A photochemical synthesis of substituted dihydroimidazo[1,2-a]pyridin-3(2H)-ones	16
General methods for the synthesis of styrylpyridinium salts (microreview)	16
Structural and chemical reactivity insights of a benzimidazolidinone-based N-heterocycle: a multiapproach quantum-chemical study	14
Thematic issue “Chemistry of polyheteroatomic heterocyclic systems”	14
Cyclic Isothiourea in Drug Design	13
Modern approaches to the synthesis of phenazine derivatives (microreview)	13
Unexpected products of the reaction of purine nucleic base perchlorates with acetylacetone causing single-strand breaks in the DNA molecule	13
Pseudopeptides based on nicotinic acid with 4-amidoxime unit	11
Method for the synthesis of chromenopyrimidine-fused azoles by copper-catalyzed intramolecular hetero-Diels–Alder reaction	11
Analgesic and Antidepressant Activity of 8-Substituted Harmine Derivatives	11
Structural characterization of products arising from methylsulfanyl group oxidation in pyrimidine derivatives using 13C NMR spectroscopy	10
Unexpected conversion of 4-oxo-4H-chromene-2-carboxylic acid to 2-(1,3-benzothiazol-2-yl)-4H-chromen-4-one and spiro[1,4-benzothiazine-2,2'-chromene]-3,4'(3'H,4H)-dione	10
Reactions of Quinolinecarbaldehydes with Arenes under Superelectrophilic Activation. NMR and DFT Studies of Dicationic Electrophilic Species	10
A new approach to the synthesis of 17-pyrazolylandrostane	9
The synthesis of ethyl 2-amino-1-(aryl)-5-(arylcarbamoyl)-6-oxo-1,6-dihydropyridine-3-carboxylates	9
Synthesis of novel pyrimido[4,5-d]pyrimidine derivatives from 5-acetyl-4-aminopyrimidines	9
Approaches to the synthesis of thiazolo[3,2-a]pyridines (microreview)	9
An efficient one-pot synthesis of indolyl-4H-chromene derivatives	8
Nina Nikolaevna Makhova (31.07.1938–22.06.2021)	8
Synthesis and Chemical Transformations of 2-imino-2,5-dihydrofurans	7
Synthesis of sulfolanopyranochromenones by the reaction of 2-benzylidene-3-methyl-4-nitro-2,5-dihydrothiophene 1,1-dioxides with 4-hydroxycoumarin	7

Alkaloid-like annulated pyrano[4,3-b]pyrroles: antiviral activity and hydrolysis	7
Mechanochemical synthesis of halogenated heterocyclic compounds	7
Synthesis of julolidine derivatives via SnCl4-promoted spirocyclization of (1-alkyltetrahydroquinolin-8-yl)methylidene-1H-imidazol-5(4H)-ones	7
Synthesis and neuroprotective activity of a (–)-cytisine-isoflavone conjugate	7
The effect of substituents on carbon–carbon double bond isomerization in heterocyclic hydrazine derivatives	7
Synthesis of sulfolanooctahydrochromenones from 2-benzylidene-3-methyl-4-nitro-2,5-dihydrothiophene 1,1-dioxides	7
Synthesis of 2,3-dihydro-1,4-benzoxathiine derivatives	7
The synthesis of novel 1-hetarylmethylidene-4-sulfanylfuro-[3,4-c]pyridin-3(1H)-ones	7
One-pot transformations of tetracyanocyclopropanes into highly functionalized pyridines	7
Pyrazoles, isoxazoles, and 1,2,3-triazoles as analogs of the natural cytostatic combretastatin A-4: efficient routes of synthesis, tubulin inhibition, and cytotoxicity	6
Thematic issue “Cycloaddition reactions: recent progress”	6
Microwave synthesis of triterpenoid-annulated imidazo[1,2-a]pyridines	6
Recent advances in the application of Meerwein arylation for the synthesis of complex heterocycles at the Ivan Franko National University of Lviv (microreview)	6
A formal [4+1] cycloaddition of dimethoxycarbene to 3-perfluoroacyl-4H-chromenes: the synthesis of areno-condensed 7,7a-dihydro-4H-furo[3,4-b]pyrans	6
Regioselective [3+2] cycloaddition of nitrile oxides to 1Н-pyrrole-2,3-diones: synthesis of spiro[pyrroledioxazoles]	6
An AgOAc-catalyzed reaction of 3-nitro-2H-chromenes with ethyl diazoacetate: an efficient one-pot synthesis of ethyl 3,4-dihydrochromeno[3,4-c]pyrazole-1-carboxylates	6
Synthesis of functionalized 1-methylchromeno[3,4-b]pyrrol-4(3H)-ones via the Barton–Zard reaction starting from pseudonitrosites	6
Synthetic Methods toward Phosphacoumarins (microreview)	6
In silico Study of Conjugated Nitrogen Heterocycles Affinity in their Biological Complexes	6
Methods for the synthesis of imidazo[2,1-b][1,3]thiazines, their annulated and hydrogenated analogs	6
Synthesis of C3h-symmetric benzotripyrrole derivatives as monomers for organic frameworks	6
Synthesis of 2H-pyrano[3,2-g]quinolin-2-ones containing a pyrimidinone moiety and characterization of their anticoagulant activity via inhibition of blood coagulation factors Xa and XIa	6
The Diels–Alder reaction in the synthesis of fused heterocyclic aromatic compounds	6
Recent developments in the synthesis of piperazines (microreview)	6
Chemosensors based on 5-ethylidene-substituted barbituric acid derivatives (microreview)	6
The synthesis of 3-nitro-4H-benzo[h]chromenes	6
Metal oxides in multicomponent synthesis of heterocycles	6
Synthesis and Antiviral Activity of N-Heterocyclic Hydrazine Derivatives of Camphor and Fenchone	5
Discovery of indole-3-acetic acid derivatives containing 1,3,4-thiadiazole thioether and amide moieties as novel antibacterial agents	5
Syntheses of quinolines and their derivatives from α,β-unsaturated aldehydes	5
An overview of the synthetic routes toward [1, 2, 4]triazolo[3,4-b][1,3,4]thiadiazoles (microreview)	5
5(4)-Aminopyrazoles as effective reagents in the synthesis of pyrazolo-annulated pyridines	5
Three-component synthesis of 2-acyl-2,3-dihydro-4H-thiochromeno[4,3-b]furan-4-ones and their reductive rearrangement into 4H,5H-thiochromeno[4,3-b]pyran-5-ones	5
Synthesis of isomeric 4-(N-methyltetrazolylamino)-2-phenyl-4H-thiopyrano[2,3-b]quinoline-3-carbaldehydes and 4-hydroxy-2-phenyl-4H-thiopyrano[2,3-b]quinoline-3-carbaldehyde based on tandem thiol-Micha	5
[Difluoro(pyridinyl)methyl]phosphonates	5
Synthesis and photophysical properties of the products of the reaction of 5-methyl-7-phenyl[1,3]oxazolo[5,4-b]pyridin-2(1H)-one with amino acids	5
Intramolecular Diels–Alder reaction in the synthesis of 5-arylisoxazolylmethyl- and 4,5-dichloroisothiazolylmethyl-3a,6-epoxyisoindol-3-ones	5
Synthesis of new class of trithiadiazacycloalkane 1,1-dioxides using Yb(Sm)-contaning catalysts and conformational analysis of the macroheterocycles	5
A simple method for the synthesis of isoindoline derivatives	5
Recent methods for the synthesis of fused pyrazolo[3,4(4,3)-d]thiazoles and pyrazolo[3,4(4,3)-d][1,4]thiazines (microreview)	5
An azo coupling of berberine derivatives: an experimental and quantum-chemical study	5
The synthesis and antitubercular activity of 4,5-dihydro-1H-pyrazole derivatives with a basic epoxybenzo[7,8]oxocine framework	5
Electrophilically activated nitroalkanes in the synthesis of substituted 1,3,4-oxadiazoles from amino acid derivatives	5
New methods for the synthesis of pyrrolo[1,2-x][1,4]diazepines and their (het)arene-annulated analogs (microreview)	5
Synthesis of imidazo[2,1-b]thiazol-5-amines using Groebke–Blackburn–Bienaymé multicomponent reaction (microreview)	5
Synthesis and fungicidal activity of novel 6H-benzimidazo[1,2-c][1,3]benzoxazin-6-ones	5
A simple and efficient synthesis of 1,3,6-trisubstituted pyrazoloquinolines via intramolecular cyclization – optimization studies	4
Synthesis of tellurium-substituted azoles (microreview)	4
Synthesis of cyclic aza-peroxides (microreview)	4
A sequence of acylamination and acylation reactions in polyphosphoric acid – a novel approach to the Friedländer synthesis of 2-arylquinolines	4

Asymmetric synthesis of pyroglutamic acids via Ni(II) complex methodology	4
Lewis acid catalyzed condensation of 2-aminohetarene N-oxides with N,N-dimethylformamide dimethyl acetal	4
The synthesis of indolizin-1-ylphosphonates via the reaction of ethynylphosphonates with pyridinium methylides	4
Stereoselective synthesis of tetrahydropyrimidin-2(1H)-ones (minireview)	4
Synthesis of spiro[imidazole-4,3'-quinolin]ones from [2-(dimethylamino)benzylidene]-2-(methylsulfanyl)imidazolones	4
Recent methods in the synthesis of chromeno[2,3-d]pyrimidines	4
A three-component cycloaddition of alkyl trifluorodiazoethane for the synthesis of trifluoromethylated isoxazolines	4
Recent advances on heterocyclic compounds with antiviral properties	4
Synthesis and structural characterization of N,N',N'',N'''-tetrasubstituted cyclams	4
Synthesis of chromeno[2,3-c]pyrrol-9(2H)-ones (microreview)	4
Synthesis and permethylation of methyl 5-(2-chloropyridin-3-yl)pentanoates	4
Marina Abramovna Yurovskaya (1.03.1940–21.05.2021)	4
Synthesis and NMR spectra of [15N]indole	4
Acenaphthenequinone-Based Stabilized Azomethine Ylides in (3+2) Cycloaddition Reactions with 1,5-diarylpent-4-ene-1,3-diones	4
A study of the reactivity of 2,4-diphenylfuran	4
Unexpected ANRORC rearrangement in pyran ring	4
Synthesis and properties of heterocycle-containing podands	4
Schizocommunin-inspired heterocyclic hybrid molecules	3
Density Estimation Method for Individual Compounds from X-Ray Diffraction Analysis of their Solvated Forms	3
Oxidative rearrangement of 3-aryl-1H-benzo[f]chromenes into 2-aroyl-1,2-dihydronaphtho[2,1-b]furans	3
Bu3P-mediated acylation of (E)-7-arylidene-6,7-dihydroindolizin-8(5H)-ones with acyl chlorides	3
Synthesis and SAR of phenylazoles, active against Staphylococcus aureus Newman	3
A synthesis of carbonyl-substituted 4-aryl-4H-benzo[h]chromenes based on a three-component condensation of α-naphthol, aromatic aldehydes, and β-enaminones	3
Synthesis of spiro[imidazole-4,3'-thiochroman]ones from [2-(benzylsulfanyl)benzylidene]imidazolones	3
Synthesis of 3(5)-aryl-5(3)-pyrazolyl-1,2,4-oxadiazole nitro derivatives	3
1-Aryl-4-(2-oxoalkylsulfanyl)-2,3(5H)-benzodiazepines: synthesis and thiophene ring annulation to 1,2-diazepine core	3
Synthetic application of oxiranecarbonitriles (microreview)	3
A one-pot synthesis of 3-nitro-2H-thiopyrans and their selective reduction to 3-nitro-3,4-dihydro-2H-thiopyrans	3
Synthetic transformations of sesquiterpene lactones. Controllable synthesis of 11,13-dihydroisoalantolactone azides and 13-(1,2,3-triazolyl)eudesmanolides based on sesquiterpene lactones	3
Tetrahydroazepines with an annulated five-membered heteroaromatic ring	3
[3+2] Annulation of 2-substituted 3-nitro-2H-chromenes with mercaptoacetaldehyde: stereoselective synthesis of tetrahydro-4H-thieno[3,2-c]chromen-3-ols	3
Synthesis of the First Dithiaaza-17-Crown-5 Ethers Containing Piperidin-4-One Subunit	3
The synthesis and cytotoxic activity of N-unsubstituted 3-aryl-4-(trifluoromethyl)-4H-spiro[chromeno[3,4-c]pyrrolidine-1,11'-indeno[1,2-b]quinoxalines]	3
Tandem Synthesis of Novel thiazole-substituted pyrrolo[1,2-d][1,2,4]triazin-4(3H)-one Derivatives and their Theoretical Pharmacokinetic Profiles	3
Oxidative cyclization of 5-aryl-1-benzyl-1,2,3-triazoles bearing electron-rich aromatic groups: ortho/ortho and ortho/ipso coupling	3
Formation of 4-(het)aryl-3H-1,5-benzodiazepine-2-carboxylates from (het)aroylpyruvate esters and o-phenylenediamine	3
3-Cyanothiete 1,1-dioxide: synthesis and cycloaddition reactions	3
Synthetic approaches toward 2,3-dihydroquinazolinones (microreview)	3
Cascade assembling of aldehydes and two molecules of dimedone into 4H-spiro[1-benzofuran-2,1'-cyclohexane]-2',4,6'-triones under column chromatography-free protocol at room temperature	3
A General Approach to 4-unsubstituted and 4-alkyl-substituted 5-acyl-1,2,3,4-tetrahydropyrimidine-2-thiones(ones) via α-(thio)ureidoalkylation of 1,3-diketones or β-oxoesters	3
Selective synthesis of a novel glycoluril-based hybrid compound with high application potential	3
Transition metal catalyzed C–H functionalization of arylindazoles: assembly of highly functionalized heterocycles (microreview)	3
An efficient synthesis of (E)-3-[(dimethylamino)methylidene]furan-2(3H)-thiones and transamination reactions thereof	3
Three-component condensation of cyclic 1,3-dicarbonyl compounds, N-phenacylpyridinium salts, and isatins or aromatic aldehydes as a method for the synthesis of novel condensed 2-aroyl-2,3-dihydrofuran	3
Modern Methods for the Synthesis of Cyano-Substituted Bipyridine Derivatives (microreview)	3
Silver-assisted palladium-catalyzed one-pot synthesis of 3-(hetero)arylmethyl derivatives of imidazo[1,2-a]pyridines	3
4-(N-Boc-amino)-1Н-1,2,3-triazolecarbothioamides in the synthesis of a new heterocyclic [1,2,3]triazolo[4,5-e][1,4]thiazepine system	3
Porphyrins with Phenolic Fragments at the Periphery of the Macrocycle as Perspective Antioxidants, Cytoprotectors and Heavy Metal Scavengers	3
Synthesis of alkenyl- and alkynyloxazoles and –oxazolines using tosylmethyl isocyanide as a key building block (microreview)	3