OOIR: Observatory of International Research

Papers

(The median citation count of Circulation Research is 0. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
In This Issue	599
Meet the First Authors	551
Meet the First Authors	413
Abstract P1169: BubR1 Regulates Cardiac Development Through CamkII In Vivo	390
Abstract P1124: Immunosuppression Drug Mediated Cardiovascular Effects	320
Abstract P3070: Aortic Valve Calcification Is Accelerated By DNMT3A And TET2 Gene Driver Mutations Associated With Clonal Hematopoiesis	238
Abstract P3102: Sex Differences In Outcomes Among Heart Failure Hospitalizations	235
Abstract P3132: Tgfβ Signaling Triggers Nonmyocyte Gene Expression In Tbx18-induced Pacemaker Myocytes And Abbreviates Their Automaticity	225
Abstract P2116: Role Of Cardiomyocyte Specific Pellino-1, An E3 Ligase On Therapeutic Angiogenesis And Attenuation Of Ventricular Remodeling In A Murine Myocardial Infarction Model	224
Abstract P3018: SCARNA20 Promotes M2 Macrophage Polarization Under Endotoxemia And Reduces Inflammation	178
Abstract P3133: Endothelial Nup93 Selectively Regulates The LaminB1 Isoform To Limit Features Of Cellular Senescence And Consequent Endothelial Dysfunction	164
Abstract P3060: Modeling Immune Checkpoint Inhibitor Associated Myocarditis In Vitro	163
Abstract P3016: Pathologic Matrix Markers Are Differentially Modulated By VSMC-Specific SGK-1 Activity In Hypertension And Abdominal Aortic Aneurysm	163
Abstract P3061: Development Of Molecular Targeted Therapy Against Right Ventricular Failure: Involvement In Complement C3- Factor D- C3a Pathway	139
Abstract P1042: Endothelial Hif-2α Expression Prevents Against Myocardial Infarction Induced Heart Failure And Cardiac Microvascular Barrier Dysfunction	137
Abstract P3053: Mitochondrial Calcium Accumulation Drives The Progression Of Non-ischemic Heart Failure: Integrated Lessons From Genetic Mouse Models	136
Abstract P2045: Transcriptome Versus Proteomic Discrepancy Is Associated With Structural-functional Dys-synchrony In Reductive Stress Myocardium	136
Abstract P3084: Neutrophil Expansion And Netosis Are Essential For Adverse Left Ventricular Remodeling And Dysfunction In Chronic Ischemic Heart Failure	133
Abstract P3146: Cardiac Stress-induced Arrhythmias And Myocardial Infarction Via Specific Genetically Phosphodeleted Sites In Connexin 43 Channels	131
Abstract P3023: Endothelial Pparδ Deletion Exacerbates Endotoxemia-Induced Vascular Injury And Inflammation	129
Abstract P2118: Intervention With The Adiponectin Mimetic Peptide ALY688 Protects Against Cardiac Dysfunction Induced By Ischemia Reperfusion Injury	128
Abstract P2068: β _Iv -spectrin/stat3 Are Responsible For Concentric Versus Eccentric Cardiac Hypertrophy	125
Abstract P3063: Selective Release Of Mitochondrial Dna After Brief Myocardial Ischemia	125
Abstract P1172: Shear-mediated Remodeling Of Platelet Surface Glycosylation: How Can Platelets Trim Their Sugar Coats?	124
Abstract P1130: Enhanced Electrophysiological Maturation Of Human Pluripotent Stem Cell Derived Cardiomyocytes By An Optimal Combination Of Metabolic Modulators	121

Abstract P3196: Voluntary Exercise Training Does Not Prevent High Phosphate Diet-induced Mitochondrial Dysfunction	121
Abstract Fri054: Outcomes of Colorectal Cancer Patients with Comorbid Heart Failure: A 22-Year National Analysis	120
Abstract Fri116: Acute loss of PGC1α in adult cardiomyocytes reduces ischemia-reperfusion injury	116
Abstract Thu149: Pathogenic desmoplakin variants induce long cell-membrane caveolin-1 (CAV1) cluster formation and decrease CAV1-mediated TGFβ1 receptor endocytosis via beclin-1 deficiency	111
Abstract Fri122: Intermembrane Space Proteases In Mitochondrial Stress Response	102
Abstract Fri083: A Cardiac Ryanodine Receptor C-terminal Truncation Causes Calcium Release Deficiency Syndrome, but not Catecholaminergic Polymorphic Ventricular Tachycardia	100
Abstract Thu102: Brd4-mediated 3D chromatin architecture determines old donor heart preservation quality	99
Abstract Wed012: Assessing Mouse Transverse Aortic Constriction Studies in AHA Journals for Reproducibility and Translational Potential	94
Abstract Fri082: Early renal denervation reduces ventricular arrhythmias by mitigating Angiotensin II-promoted neuronal remodeling in the stellate ganglion after acute myocardial infarction	94
Abstract Fri010: Expanding High Throughput CaMKII Inhibitor Screen to Commercial “Hinge Binder” Drug Library	88
Abstract Thu032: Systematic CRISPR Knockout Screen Uncovers Epigenetic Barriers to Direct Cardiac Reprogramming	88
Abstract Fri061: Cancer Cachexia in a Dish: Insight into Atrogin-1 mediated Protein Degradation and Calcineurin Modulation in a Novel hiPSC-CM Model of Cancer-Induced Cardiomyopathy	88
Extracellular Perinexal Separation Is a Principal Determinant of Cardiac Conduction	87
Ubiquitin Ligase RBX2/SAG Regulates Mitochondrial Ubiquitination and Mitophagy	87
Abstract NBT103: Pharmacological Inhibition of DYRK1A Induces Cardiomyocyte Cell Cycle Activity	87
Endothelial Senescence: A New Age in Pulmonary Hypertension	86
In This Issue	85
Editors and Editorial Board	85
SLC39A13 Regulates Heart Function via Mitochondrial Iron Homeostasis Maintenance	84
Variables Predicting Experimental Stroke Outcome: How Well Do We Know Our Models?	84
Antiarrhythmic Mechanisms of Epidural Blockade After Myocardial Infarction	83
AKAP12 Overexpression Affects Cardiac Function via PDE8	81
COVID19 Impairs Cardiac Function via Endothelial H19 and IL6 Signaling	80
A Critical Role for ERO1α in Arterial Thrombosis and Ischemic Stroke	80
Abstract Tu145: Exploring Naltrindole’s hypercontracture attenuating effects during myocardial ischemia via a novel mechanism that produces cardioprotective effects in myocardial ischemia/reperfusion	80
Abstract We023: P53 Activation Promotes Maturational Characteristics of Pluripotent Stem Cell-derived Cardiomyocytes in 3D Suspension Culture via FOXO-FOXM1 Regulation	79
Abstract Mo112: ARA290, a small peptide non-erythropoietic Erythropoietin derivative, ameliorates heart functional deterioration in a chronic cardiac stress model	78
Abstract Mo057: Computational Modeling Reveals Enhanced Ca2+-Driven Arrhythmias in Female Patients with Atrial Fibrillation	78
Abstract We111: 3D spheroids composed by induced Skeletal Muscle Progenitor Cells and Mesenchymal Stem Cells derived from human Pluripotent Stem Cells can recapitulate embryonic niches in hindlimb isc	76
Abstract Mo046: GJA1-20k Restores Connexin-43 Trafficking and β-Catenin Signaling in Myocytes Lacking Desmoplakin	75
Abstract Mo130: Epigenetic Mechanisms Regulate Sex Differences in Cardiac Reparative Functions of Bone Marrow Progenitor Cells	74
Abstract We048: Exon-skipping therapy can restore functional dystrophin attenuating calcium overload for DMD cardiomyopathy with mutations in actin-binding domain 1	74
Abstract We117: Preclinical Evidence of Long-term Efficacy and Safety of LX2020, an AAV based Plakophilin-2 Gene Therapy, for the Treatment of Arrhythmogenic Cardiomyopathy	71
Abstract Mo090: Altered Cardiac Cell Populations in Hypoplastic Left Heart Syndrome	70
Abstract Tu049: Stabilization of RyR2 with dantrolene treatment ameliorates left ventricular remodeling and ventricular tachycardia after myocardial infarction	70
Calcium Oscillations Within Juxtaglomerular Cell Clusters Control Renin Release	70
Increased Ca ²⁺ Transient Underlies RyR2-Related Left Ventricular Noncompaction	69
Neuroinflammation Plays a Critical Role in Cerebral Cavernous Malformation Disease	68
Follistatin From hiPSC-Cardiomyocytes Promotes Myocyte Proliferation in Pigs With Postinfarction LV Remodeling	68
Dot1L-H3K79me2-Tbx6 Axis: A Novel Therapeutic Target for Preventing Cardiac Failure	68
Tenascin-X Mediates Flow-Induced Suppression of EndMT and Atherosclerosis	67
Cardiopulmonary Consequences of Vaping in Adolescents: A Scientific Statement From the American Heart Association	66
Cerebral Hemorrhage: Pathophysiology, Treatment, and Future Directions	65
Cyclin D-CDK4 Disulfide Bond Attenuates Pulmonary Vascular Cell Proliferation	65
Abstract P1016: Modeling Ventricular Hypoplasia In Pulmonary Atresia With Intact Ventricular Septum Using Patient-Specific Induced Pluripotent Stem Cells	64
Deficient Chaperone-Mediated Autophagy Promotes Inflammation and Atherosclerosis	64
Endothelial Cells Induced Progenitors Into Brown Fat to Reduce Atherosclerosis	64
Abstract P3018: A Requirement For P21 Activated Kinase1 To Preserve Cardiac Function And Metabolic Homeostasis	63
Abstract P3128: Obesogenic Diet Promotes Endothelial-to-Mesenchymal Transition In Adipose Tissue	63
Abstract P3164: Podocalyxin, A Renal Podocyte Specific Protein Expression In Urine Exosome Acts As A Marker For Podocyte Injury During Sars-cov-2 Infection	61

Abstract P3031: The Cross Talk Between Increased Abdominal Adiposity And Calcification Of Aortic Valve	61
Abstract P2094: The Regulatory Role Of Sirtuin 6 In Coronary Microcirculation In Hfpef	61
Abstract P1182: The Genetic Dissection Of Rpl3l As A Causal Gene For Neonatal Dilated Cardiomyopathy And Left Ventricular Noncompaction	61
Abstract P2078: Vasohibin Inhibition Improves Myocardial Relaxation In A Rodent Model Of Heart Failure With Preserved Ejection Fraction	60
Abstract P1184: Spatiotemporal Proteomics Approach To Discern New Features Of Carfilzomib-mediated Cardiotoxicity	60
Abstract P3029: The Role Of Fatty Acid Synthase In The Modulation Of Vascular Smooth Muscle Cells Into A Foam Cell Phenotype	60
Abstract P3010: The C10X Polymorphism In The CARD8 Gene Is Associated With The Levels Of CCL20 And IL-6 Proteins In Healthy Young Men	59
Abstract P1153: ANT-Dependent MPTP Contributes To Necrotic Myofiber Death In Muscular Dystrophy	59
Abstract P2171: Lentivirus TAZ Gene Therapy Restores Metabolic Functions In Taz Ko Mice Model Of Barth Syndrome	58
Abstract P1162: Nedd4-2 Inactivation Underlies The Increase In Cardiac Sodium-dependent Glucose Cotransporter-1 In Diabetic Hearts	58
Abstract P2038: Role Of The Microtubule Network In Right Ventricle Passive Viscoelasticity With Pulmonary Hypertension Development	58
Abstract P1049: Determination Of Proteome-wide Post-translational Modifications By Lysine Acetylation In Ischemic Cardiac Cells	58
Abstract P2085: Whole Blood Microfluidics To Assess Direct Oral Anticoagulant (doac) Activity And Reversal In Neonatal Cardiac Patients	57
Abstract P2095: Role Of Intraplaque Lipids In Atherosclerotic Plaque Vulnerability	57
Abstract P3129: Functional Coupling Of TRPM2 And Extrasynaptic NMDARs Exacerbates Excitotoxicity In Ischemic Stroke	57
Abstract P3047: Identification Of Role Of Intracellular Chloride Channel Clic4 In Diabetic Cardiomyopathy.	56
Abstract P1116: Genetic Mapping Of Cardiomyocyte Ploidy Phenotypes To Identify Genetic Determinants Of Outcomes After Infarction	56
Abstract P1011: Pharmacological Targeting Of Tip60 For Heart Regeneration And Repair	55
Abstract P1122: Coupled Myovascular Expansion Directs Cardiac Growth And Regeneration	55
Abstract P1121: Transposition Of Great Arteries - Genetics And Beyond	55
Abstract P1044: A Drug-Like Activity Of Polydopamine Nanoparticles Mediates Cardiomyocyte Bio-Modulation And Maturation	55
Abstract P3023: The Regulatory Role Of Mir-21 In Heart Failure With Preserved Ejection Fraction (hfpef)	55
Abstract P3125: Cldn11 Is A Candidate For Vascular Smooth Muscle Cell Plasticity Regulator In Atherosclerosis Pathology	54
Abstract P2115: Differential Cardiac Remodeling Profile Of Immunosuppression Drugs	54
Abstract P2142: Evaluation Of Novel A3 Adenosine Receptor Agonist In Hypertension	54
Abstract P1068: BubR1 Is A Novel Regulator Of Cardiac Development And Conduction	54
Abstract P1101: Mitochondrial Ca Uniporter Complex, ROS And CaT Alternans	54
Abstract P1085: Transient Receptor Potential Cation Channel Subfamily M Member 7 Deficiency Prevents Ventricular Tachycardia During Myocardial Ischemia Reperfusion	54
Abstract P2092: The Late Sodium Current Conditions Myocardial Repolarization And Relaxation Of The Aged Heart	53
Abstract P2064: A Specialized Centrosome-Proteasome Axis Mediates Proteostasis And Influences Cardiac Hypertrophy	53
Abstract P3118: Gender Differences In The Efficacy Of A Mobile-based Self-management Program For Patients With Heart Failure	53
Abstract P1075: Igf-1 Signaling And Nuclear Localization Of Pdgfralpha Tyrosine Kinase Activity Control The Fibrotic Response Of Mesenchymal Stromal Cells To Myocardial Ischemia	52
Abstract P1121: Substrate Rigidity And Mybpc3 Genotype Regulate Development Of Hypertrophic Cardiomyopathy Structural And Functional Phenotypes In Human Ipsc-derived Micro-heart Muscle Arrays	52
Stem Cell Therapy Targets: Repêchage!	52
Abstract P1072: Microneedle Patch Loaded With Il-4 Macroparticles Facilitates Heart Repair Through Macrophages Mediated Cardiomyocyte Phenotype Transition	52
Cyclophilin(g) a Knowledge Gap in Heart Failure Pathogenesis	52
Abstract P2114: Chromatin Accessibility Governs Mechanosensitive Gene Expression In Cardiac Fibroblasts	52
Correction to: mTORC1 Signaling in Brain Endothelial Progenitors Contributes to CCM Pathogenesis	51
In this Issue	51
Meet the First Authors	51
Abstract Tu125: Loss of mitochondrial magnesium leads to hepatic ketogenic insufficiency and accelerates the progression of cardiac hypertrophy	51
Introduction to the Compendium on Stroke and Neurocognitive Impairment	51
Abstract We046: Building Mass or Strength: Stage-specific Effects of Insulin and Wnt on Cell Fate Decisions in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes	50
Abstract We097: Dual Targeting CXCR4 and CXCR7 Prevents Doxorubicin-Induced Cardiotoxicity by Eliminating Cardiac Inflammation and Preserving Cardiomyocyte Function	50
Abstract Mo016: Atrial Fibrillation Outcomes in Carcinoid Tumor: A National Inpatient Sample (NIS) Study (2018-2020)	49
Abstract Tu117: Unraveling the Role of Mitochondrial Ribosomal Protein L7/L12 (MRPL12) in Diabetic Cardiomyopathy	49
Abstract Tu021: Genome-wide CRISPR Screen In Vivo Decodes Monocyte Infiltration Associated With Abdominal Aortic Aneurysm	49
Abstract Mo117: Investigation of Mechanisms to Modulate Contractility in 13-Lined Ground Squirrels	48
Abstract We063: CD73 EXPRESSION ON NEUTROPHILS PROTECTS AGAINST CARDIOMYOCYTE DAMAGE DURING INVASIVE STREPTOCOCCUS PNEUMONIAE INFECTION	48
Abstract Tu042: Fatty Acid Dysregulation Drives Cardio-Hepatic Crosstalk in Heart Failure with Preserved Ejection Fraction (HFpEF)	48
Abstract Mo085: Direct effect of sodium-glucose cotransporter 2 (SGLT2) inhibitors on cardiomyocyte function as a potential therapy for Phospholamban cardiomyopathy	48
Abstract Tu074: A Potential Link Between Stress Kinase JNK2 and AKAP-1 in Catecholamine-Induced Acute Heart Failure	48
Abstract Tu051: ROR2 Drives Right Ventricular Failure Via Proteostatic Imbalances	48
Abstract Mo075: Cigarette smoking causes somatic mutations in cardiac endothelial cells	48
Abstract Tu096: The Aryl Hydrocarbon Receptor Agonist, L-Kynurenine, Modulates Cardiac Fibroblast Activation and Antigen Presentation	47
Targeting Platelet MCU: A Promising Therapeutic Strategy?	46
Abstract We038: Metal-organic frameworks as next-generation cardiac therapeutics	46
Abstract Tu094: p53 Regulates the Extent of Fibroblast Proliferation and Fibrosis in Left Ventricle Pressure Overload	46
Na ⁺ , K ⁺ -Pump/Phospholemman Are Concentrated at Intercalated Discs for Conduction	46
Abstract Tu004: Global distribution of cardiac exosomes after myocardial infarction	46
Lactylation of HADHA Promotes Sepsis-Induced Myocardial Depression	45
Transportation-Related Carbon Footprint of Coronary Heart Disease Ambulatory Care in the United States	45
March2 Alleviates Aortic Aneurysm/Dissection by Regulating PKM2 Polymerization	45
Mitochondrial Creatine Kinase Attenuates Pathologic Remodeling in Heart Failure	45
Sbk2, a Newly Discovered Atrium-Enriched Regulator of Sarcomere Integrity	45
Melanocortin System Activates Carotid Body Arterial Chemoreceptors in Hypertension	45
Abstract Thu103: Gene Expression Analysis Identifies Inflammatory and Oxidative Stress Pathways with Potential Therapeutic Implications in Abdominal Aortic Aneurysm	44
BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes	44
Abstract Thu172: Extracellular Vesicle-Encapsulated Adeno-associated Virus for Targeted Gene Delivery to the Heart: Efficient Cardiomyocyte Delivery in a Pre-Clinical Swine Model	44
Cardio-Protective Messengers From “Good Fat”	44
Abstract Wed077: The role of senescence in HFpEF induced by cardiometabolic syndrome	43
Abstract Thu159: Sex-specific differences in transcriptomic profile in black individuals to predict cardiovascular health	43
Abstract Fri080: Kynurenic acid mitigates doxorubicin-cardiomyopathy via improving mitochondrial function and silencing ATP synthase inhibitory subunit 1	43
Abstract Wed123: Multiscale Analysis of the Role of Skeletal Muscle Actin Mutations in Causing Dilated Cardiomyopathy	43
Abstract Thu033: SUMO2/3 excludes YAP5SA from the nucleus and inhibits cardiomyocyte proliferation	43
Abstract Thu128: Chemokine CCL17：bridging innate and adaptive immunity to drive thoracic aortic aneurysm progresssion	42
Abstract Wed089: Deciphering transcriptome and cell-cell communication signature in heart failure with preserved ejection fraction at single cell resolution	42
Abstract Fri005: Novel Gene Therapy Cardiomyocyte-YAP ^on Protects Mouse Heart from Myocardial Infarction	42
Abstract Wed122: LRRC14B is Essential for Cardiac Function via Sarcomeric Protein Quality Control	42
Abstract Thu023: Inter-Organ Comparison Identifies Shared MicroRNAs during Maturation	42

Abstract Wed023: Ufmylation induces adaptive cardiac hypertrophy and protects against beta-adrenergic signaling-induced heart failure	42
Abstract Wed143: Acetylcholine-loaded Nanoparticles Protect Against Myocardial Injury In In Vitro Cardiac Spheroids and In an I n Vivo Myo	42
Abstract Fri020: Plasminogen Activator Inhibitor-1 Governs Vascular Aging	42
Mechanism of Ventricular Tachycardia Occurring in Chronic Myocardial Infarction Scar	41
In This Issue	41
Abstract Fri031: Interleukin-13 Signaling to Cardiac Myofibroblasts Exacerbates Fibrosis in the Post Myocardial Infarction Response	41
Abstract Fri141: Effects of Cardiac-Specific EMRE Deletion on Complex I Activity in Ischemia/Reperfusion	41
Abstract Wed066: Modulation of YAP/TEAD1 Signaling by O-GlcNAcylation in Cardiac Hypertrophy	41
Keeps Cardiac Pericytes in Good Shape: Regulator of G-Protein Signaling-5	41
DNA Methylation Age Mediates Effect of Metabolic Profile on Cardiovascular and General Aging	40
NEDD4–Mediated GSNOR Degradation Aggravates Cardiac Hypertrophy and Dysfunction	40
Neuron-Restrictive Silencer Factor Limits Myocyte Gα _O Expression and Is Protective in Heart Failure Progression	40
p53 Regulates the Extent of Fibroblast Proliferation and Fibrosis in Left Ventricle Pressure Overload	40
Targeted Mito- and Cardioprotection by Malonate	39
Abstract Tu143: Hsp90β Facilitates Cell Death During Acute Cardiac Ischemia/Reperfusion Injury	39
Abstract We073: CLEC4E Signaling in Myocardial Ischemia-Reperfusion Injury	39
Abstract We002: A natural loss-of-function deletion of the cytohesin 1 (Cyth1) gene in BALB/cByJ mice does not impact cardiomyocyte polyploidy	39
Abstract We026: Foxk1 and Foxk2 Promote Cardiomyocyte Proliferation and Heart Regeneration	39
Abstract Tu061: Pericyte-mediated perivascular fibrosis in the pressure-overloaded heart is dependent on TGF-β signaling and is restrained by ITGB1.	39
Non-Canonical TERT Activity Initiates Osteogenesis in Calcific Aortic Valve Disease	39
Social Determinants of Cardiovascular Disease	39
Abstract Mo015: Myeloid Specific PD-L1 Deletion Promotes Cardiac Dysfunction And Myocardial Inflammation	39
Abstract Tu107: Decreased Mitochondrial Protein Expression Accompanies Atrial Hypertrophy but Precedes Atrial Fibrillation Onset in a Mouse Model of Spontaneous Atrial Fibrillation	39
Abstract Mo050: Fluoroquinolones and the Risk of Aortic Aneurysm or Aortic Dissection: Evidence From a Nationwide Nested Case-Control Study Paralleled With Matched Experimental Models	38
Abstract Or106: DNA Double-stranded Breaks, a Hallmark of Aging, Defined at the Nucleotide Resolution, Are Increased and Associated with Transcription in the Cardiac Myocyte Genome in LMNA-Cardiomyopa	38
Abstract Mo054: Long Noncoding RNA LINC00667 Downregulation Leads to SCN5A Alternative Splicing and Arrhythmogenesis	38
Abstract Mo033: Circulating Long Noncoding RNA Expression Signature Predicts Adverse Cardiovascular Outcomes in Patients with Coronary Artery Disease	38
Abstract Tu079: The Calcium Handling Machinery and Electrophysiology is Remodeled in Friedreich’s Ataxia	38
Abstract Or110: Inflammation-induced endothelial cell activation and angiogenic sprouting are downmodulated by ubiquitin-specific peptidase 20	37
Abstract P1041: Redox Regulator MnTnBuOE-PyP5+ Protects Cardiomyocyte Against Oxidative Stress Mediated Myocardial Ischemia/reperfusion Injury	37
Abstract P3115: Disruption Of Assembly By Estrogen Limits Microtubule Proliferation In Failing Heart Cells	37
Abstract Tu053: Activin Signaling Inhibition Enhances Cardiac Functional Recovery After Aortic Debanding	37
Abstract P3047: Alternative Splicing Networks During Postnatal Mouse Atria Development	37
Abstract P3120: Persistent Cardiac Dysfunction In Ovariectomized Independent Of Metabolic Disturbance	37
Abstract Or121: Druggable Genome CRISPRi/a Screens in iPSC-Derived Cardiomyocytes Identify Therapeutic Targets for Doxorubicin-Induced Cardiotoxicity	37
Abstract We133: In Silico Model of Cardiomyopathy Caused by a MYBPC3-induced HCM Mutation	37
Abstract P1181: Targeted Loss Of Sarcolemmal Membrane Associated Protein Isoform 3 (slmap3) In Cardiac Progenitors Stunts The Embryonic Growth Of Myocardium	37
Abstract P2037: Bubr1 Is A Critical Regulator Of Cardiac Aging	36
Abstract Wed062: O-GlcNAcylations Of Cardiac NHE-1 Increases Its Activity In Diabetes Mellitus Models	36
Abstract P3065: Mechanistic Insights Into Cardiac Dysfunction And Remodeling Associated With Invasive Pneumococcal Pathogenesis	36
Abstract P3113: Apyrase But Not Dipyridamole Improves Cardiac Function In Ovariectomized High-fat Diet Mice	36
Abstract P3202: The Branched Chain α-Ketoacid Dehydrogenase Kinase (BCKDK) Inhibitor BT2 Is A Mitochondrial Uncoupler	36
Abstract P2106: Transforming Growth Factor β-dependent Regulation Of Cardiomyocyte Maturation	36
Abstract Thu120: Guardians of the Artery: Long-Term CXCL5 Infusion as a Galactic Defense Against Atheroprogression	36
Abstract Wed067: The microtubule network regulates NOX2-mediated oxidative stress and Cx43 remodelling in Duchenne Muscular Dystrophy	35
Abstract Wed112: Decoding the regulatory role of functional SNP rs17617337 in human dilated cardiomyopathy.	35
Abstract Wed139: The disruption of cTnT-mediated sarcomere-mitochondrial communication results in dilated cardiomyopathy	35
Abstract Thu139: YAP Induces a Glycolytic Microenvironment to Drive Right Atrial Fibroinflammation	35
Abstract Thu096: DNMT3B-Mediated Epigenetic Reprogramming Induces Cardiomyocyte Dedifferentiation and Proliferation, Enhancing Post-MI Cardiac Regeneration	35
Abstract Or303: Activin Type IIA Receptor Inhibition Decreases Atrial Fibrillation Inducibility In Mice Via a Smurf1-Connexin43 Mechanism	35
Abstract Or401: Thioredoxin1 is a critical factor for the stability and activity of SERCA2a in the heart.	35
Abstract Fri160: Ca ^2+/ Calmodulin Dependent&Independent Regulation of Obscurin Kinase 1	34
Abstract Fri151: Trends in Heart Failure Mortality Among Patients With Standard Modifiable Cardiovascular Risk Factors: A Retrospective Analysis (1999–2020)	34
Abstract Wed005: Transient Senescence Following Myocardial Infarction: Characterization and Functional Implications in Cardiac Remodeling	34
Personal Strategies to Reduce the Cardiovascular Impacts of Environmental Exposures	33
Abstract Fri133: ChLoride Intracellular Channel 1 Prevents Juvenile Diabesity by Regulating Expression of Glucose Transporter 4	33
CD163 ⁺ Macrophages Induce Endothelial-to-Mesenchymal Transition in Atheroma	33
Transcription Factor 21 Regulates Cardiac Myofibroblast Formation and Fibrosis	33
Abstract P1082: Activation And Phosphorylation Of Rap1b In The Human Megakaryocytic Leukemia Cell Line DAMI	32
Expression of Concern: Sympathetic Activation Causes Focal Adhesion Signaling Alteration in Early Compensated Volume Overload Attributable to Isolated Mitral Regurgitation in the Dog	32
Abstract P3100: Integrating Single-Cell Transcriptomics And Light-Sheet Imaging To Elucidate The Mechanisms Of Cardiac Outflow Development	32
Abstract P1008: Bioelectric Sutures Generated From HiPSC-derived Cardiomyocytes Enable In Vitro Electrical Coupling Between Engineered Cardiac Tissues	32
Meet the First Authors	32
Abstract P1110: Identification Of Timp-1 As A Downstream Target Of The Coronary Artery Disease Risk Factor Adamts-7 In Atherosclerosis	31
Abstract P2025: BET Bromodomain Proteins Are Necessary For TGFβ2-Mediated Myofibroblast Activation	31
Meet the First Authors	31
Abstract P3052: Dysregulation Of The Ampk-drp1 Axis Promotes Pathophysiological Remodeling Of Mitochondrial Ultrastructure And Ventricular Electrophysiological Function	31
Abstract P2036: Investigating Variants Of Hdac7 In Mammalian Heart Regeneration	31
Abstract We025: Human Engineered Heart Tissues Demonstrate Clinically-Relevant Disease indicators of Duchenne Muscular Dystrophy	31
Gut-Heart Axis: The Role of Gut Microbiota and Metabolites in Heart Failure	31
Abstract EC104: Mitochondrial Microdomain Disruption Results In Sinus Node Dysfunction In Heart Failure	31
Abstract P1108: Functional Genomics Analysis Of Sox17 Locus To Define The Pathogenic Role Of FUBP1 In Pulmonary Arterial Hypertension	31
RNA Therapeutics for In Vivo CAR-Macrophage: Advancing Cardiac Immunotherapy	31
Animal Models of Cardiovascular Complications of Pregnancy	30
Abstract Wed093: Empagliflozin Reduces Skeletal Muscle Lipid Accumulation and Augments BCAA Oxidation in Cardiometabolic HFpEF	30
Abstract Thu136: Gfpt2 Modulates the Cardiac Fibroblast to Myofibroblast Transition Through Metabolic Reprogramming	30
Multimodality Cardiac Imaging in COVID	30
Abstract Wed115: RNA binding protein RBFOX2 in cardiovascular development and disease	30
Meet the First Authors	30
Necessary Role of Ceramides in the Human Microvascular Endothelium During Health and Disease	30
Inflammation in HIV and Its Impact on Atherosclerotic Cardiovascular Disease	29
Legumain Regulates Regulatory T Cells in Hypertension	29
Myeloid-Specific JAK2 Contributes to Inflammation and Salt Sensitivity of Blood Pressure	29
Advances in Acute Ischemic Stroke Therapy	29
Abstract P1155: P62 Overexpression Rescues Defective Autophagy Flux In Cardiomyocytes Deficient In P21 Activated Kinase 1	28
Heat and Cardiovascular Mortality: An Epidemiological Perspective	28
Abstract P2016: Extracellular Stiffness Induces Glucose Dysregulation Via Microtubule-dependent Mechanism	28
Abstract GS.13: Dworf Overexpression In The Heart Results In Enhanced Mitochondrial Function	28
Abstract P3022: Multiscale Characterization Of Left Ventricular Diastolic Dysfunction In Diabetic And Cardiac Myosin Binding Protein-C Phospho-Ablated Murine Models	28
Abstract P1061: Salivary Extracellular Vesicle-associated LncRNAs As Novel Non-invasive Biomarkers For Acute Decompensated Heart Failure: The Pioneering SEAL-HF Study	28
Abstract GS.04: Myocardial Tricarboxylic Acid Cycle Suppression Disrupts The Epigenetic Landscape In Human Heart Failure With Preserved Ejection Fraction	28
Intrapericardial Exosome Therapy Dampens Cardiac Injury via Activating Foxo3	28
Orai1 Inhibitors as Potential Treatments for Pulmonary Arterial Hypertension	28
Abstract P3180: Cardiomyocyte Pgc-1α Mediates The Adaptive Response To Endurance Exercise Training In Mice	27
Abstract P3059: Recombinant Adeno-associated Viral Vector 2/8 Model Of Interleukin 6 Mediated Chronic Inflammation	27