Clinica Chimica Acta

Papers
(The median citation count of Clinica Chimica Acta is 0. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
M062 Identification of biomarkers in patients with colorectal cancer in Kazakh population232
Analysis of the diagnostic and prognostic value of serum PAD2 in patients with sepsis in the intensive care unit188
T195 Plasma creatinine measurement in diabetic patients. Should we advocate the enzymatic method?146
T215 About a case: Crioaglutinine disease94
T223 Validation and clinical application of a novel platelet function analyzer (ANYSIS 200) in cardiology patients89
T258 Investigation of genetic biomarkers associated with low platelet count in normal karyotype acute myeloid leukemia82
W058 Salmonella infection among the suspected enteric fever patients81
W080 Nanoparticle-enhanced digitof for detection of e. coli directly from urine73
M102 Laboratory errors in clinical biochemistry: The quality of laboratory testing in B.P. Koirala institute of health sciences, Nepal70
M251 Potential reference measurement procedure— Determination of c-reactive protein in serum by isotope dilution mass spectrometry based on enzyme digestion63
T022 The role of antioxidant therapy in the symptomatic treatment of pancreatic cancer patients58
T040 Micrornas stimulate prostate cancer stem cell expansion by targeting genes of the apoptotic pathway57
T052 Tumor marker study in pleural fluid and tumor heterogeneity53
M003 Cytogenetic mechanisms of the aortic coarctation formation and their relationship with late postoperative complications51
W089 Emerging threat of biofilm producing MDR acinetobactercalcoaceticusbaumanniicomplex clinical isolates causing healthcare associated infections in a teaching hospital in Nepal50
W090 Effect of carbapenemase, qace, qace⊗1, and cepa genes on chlorhexidine sensitivity in clinical isolates of gram-negative bacteria with multiple resistance47
M208 Pakistan inherited metabolic disorders network (PAK-IMD-NET): Breaking silos and bringing synergies45
Editorial board member, Aims and Scope, Publication Info.44
Development of exploratory algorithms to aid in risk of malignancy prediction of indeterminate pulmonary nodules43
W139 Molecular characterization of glucose 6-phosphate dehydrogenase deficiency among selected populations in malaria endemic area of Ethiopia40
W163 Effects of cassava processing methods on insulin index, glyceamic profile, glyceamic load and index of cassava (manihot esculeuta) meals in type 2 diabetes mellitus patients seen in Benue State U40
Evaluation of a batched-extraction method for measurement of sirolimus, tacrolimus, and cyclosporine on the Architect i2000SR40
W264 A survey on RBC transfusion practice in Korea39
T124 Hormonal biomarkers associated with in-hospital mortality in therapeutic hypothermia after cardiac arrest: A case series38
T134 Establishment of algorithms and threshold of thyroid stimulating immunoglobulin for diagnosis of Graves’ disease by data mining: A Chinese multicenter study37
M080 Tinea unguium, tinea cruris and tinea corporis caused by trichophyton rurbum in HIV patient: A case report36
T274 Natural killer cell subsets and phenotypic expression of markers of activation, maturation and associated with slow progression of HIV in HAART naïve HIV patients in Addis Ababa, Ethiopia36
M085 Determinants of systemic immunity to invasive salmonella infection in endemic settings36
Evaluating the clinical effectiveness of cardiovascular precision diagnostics35
Performance evaluation and validation of high-performance liquid chromatography method for the quantification vitamins A and E35
T287 The change for qualitative balance of vascular endothelial growth factor-a may contribute to therapeutic efficacy for an anti-neutrophil cytoplasmic antibody associated vasculitis subtypes35
Assessment of an analysing system for the determination of NA+, K+, CL- and CA2+33
How did the COVID-19 pandemic impact drug trends?33
Determine the pharmacokinetics (half-life, volume of distribution and clearance) of AMB-FUBINACA in blood samples of rats using GC-MS/MS31
Interference of hemolysis in urgent clinical biochemistry examinations analyzed on DxC 700 AU and access 229
Performance evaluation of the architect hepatitis c core antigen assay vs roche HCV DUO29
The increased sensitivity of the Xpert® Xpress assay in detecting SARS-COV-2, compared to the COBAS® assay, can be attributed to the nucleocapsid gene target29
Pre-analytical issues in haemostasis29
Exploring artificial intelligence techniques for morphological analysis of digital images of peripheral blood cells: MC-80 versus HemaVision28
Indeterminate results in quantiferon-TB gold plus testing: Possible explanation and predictive parameters28
New insights in the newborn screening for methylmalonic aciduria in the Balearic Islands: Surprisingly high prevalence of CD320 gene mutation (transcobalamin receptor)28
Laboratory-based study of newborn with intrauterine growth restriction28
Treating red blood cells with dithiothreitol can help eliminate daratumumab interference in blood compatibility tests (pretransfusion testing)27
Association of miRNA-126 cycle threshold values with the blood glucose concentration27
The effect of calcium chloride on the release of platelet-derived growth factor-BB in the platelet-rich plasma products27
Hypocalcemia and hypomagnesemia among patients with depression attending KFMMC-Dhahran-KSA27
Evaluation of pre-analytical quality indicators by six sigma principle: Experience at a tertiary care hospital26
Improving of test utilization through modification of the electronic ordering system for blood zinc level26
Seroprevalence and risk factors of toxoplasmosis among pregnant women in the M’saken region (Tunisia)26
Unveiling liquid markers: The diagnostic revolution in early detection of pancreatic cancer through liquid biopsy26
Real-world data shows the effectiveness of a tetravalent vaccine against human papilloma virus types 16 and 18 in Chilean women26
Evaluation OF FGF-23 as a marker of mineral bone disease among newly diagnosed chronic kidney disease patients in a Nigerian hospital26
Evaluation of beta glucan test using kinetic turbidimetric method on toxinometer MT-6500 for detection of invasive fungal infections in hospitalized patients26
Immunoglobulin fragmentation challenges the interpretation of capillary protein electrophoresis results25
Evaluation of metabolic and endocrine profiles in the elderly25
“Revolutionizing emergency care: A comparative analysis of comprehensive point-of-care test panels vs conventional laboratory processes in the critical care& emergency medicine”24
Association of ECM remodelling marker gene polymorphisms and their serum levels in acute and recurrent myocardial infarction24
Estimation of glomerular filtration rate with cystatin C in the evaluation of cardiovascular risk24
Exploring the potency of Lamiaceae essential oils: Chemical composition and antibacterial efficacy against multidrug-resistant bacteri24
Association of single nucleotide polymorphisms in eNOS gene with development of diabetic nephropathy: A case control study24
Stability of arterial and venous gas samples stored for 20, 40 and 60 minutes after collection23
Uric acid lithiasis in southern Tunisia23
A variant reclassification of SLC12A3 of Gitelman syndrome23
Why do scientists call for action against vitamin D deficiency and what is behind the scene?23
A system troubleshooting for HIV-1 drug resistance genotyping amplification rate failure at Ethiopian public health institute HIV laboratory22
Testosterone II (TSTII) and dimension VISTA® LOCI total testosterone (TTST) immunoassays meet the CDC host certification requirements for more than four years22
Cardiorenal syndrome and diabetes mellitus in indonesian population22
Not one-size-fits-all: The types and varieties of dtc tests and their potential harms22
Principle of flow cytometry and issues in diagnosis22
Strategy to improve the turn around time (TAT) for stat samples in clinical laboratories22
Study of the association between vitamin D and anti-mullerian hormone (AMH)22
The reality of antimicrobial resistance (AMR) in Palestine and its impact on health and economy: A cross-sectional study in West Bank, Palestine22
Thyroid profile abnormalities among patients tested at the Nairobi Hospital Laboratory, Kenya22
Next step in predictive medicine: New serum biomarkers to predict acute stroke mortality21
Raman spectroscopic analysis of urine combined with machine learning identifies life-threatening inborn errors of metabolism21
Effects of obesity on liver function in children21
Antibiotic resistance profile of enterobacteriaceae isolated from infected hemodialysis catheters21
Hematological malignancies: Analysis of complete blood count (CBC) and myelogram results in the Hematology Laboratory of Hedi Chaker Hospital Sfax (South Tunisia)21
Detection of mycobacterium tuberculosis and rifampicin resistance with Xpert® MTB/RIF analysis in a tertiary hospital21
Changes in nonalcoholic fatty liver disease and M2BPHI due to lifestyle intervention in primary healthcare21
Interference in the detection of HBA1C: Detection of abnormal HB presence21
Functional characterization of novel variants found in patients with suspected Fabry disease20
Serum Gas6 contributes to clinical outcome after aneurysmal subarachnoid hemorrhage: A prospective cohort study20
Identification of cell cycle-related hub genes HMMR AND CDC25C for prognosis of head and neck squamous cell carcinoma through co-expression network analysis20
The liver and blood cells are responsible for creatine kinase clearance in blood Circulation: A retrospective study among different human diseases20
Editorial Board20
Unexpectedly low hemoglobin A1c in a patient with chronic lymphocytic leukemia20
Editorial Board20
Comparison of various E-GFR equations in estimating glomerular filtration rate in Indians20
Electrochemical biosensors for enhanced detection of diabetes mellitus19
Monitoring mutant KRAS in plasma cell-free DNA can predict disease progression in a patient with multiple myeloma: A case report19
“Extracellular Vesicle DNA: Advances and Applications as a Non-Invasive Biomarker in Disease Diagnosis and Treatment”19
Comparative study of plasma clearance of iohexol at different injection doses19
Editorial Board19
Epigenetics of Diabetes: A bioinformatic approach19
Simultaneous determination of multiple urine biomarkers for kidney injury using SPE combined with LC-MS/MS19
Plasma lipidomics reveals potential lipid markers for the prediction of delayed neurocognitive recovery after cardiac surgery with cardiopulmonary bypass19
Serum metabolomic profile of myasthenia gravis and potential values as biomarkers in disease monitoring19
Diagnostic value of Serum Amyloid A, Interleukin-6 in gravidas with spontaneous preterm birth19
The value of serum tumor-associated autoantibodies in screening and diagnosis of gastric cancer19
Quantitative analysis of soluble costimulatory molecules as potential diagnostic biomarkers for rheumatoid arthritis using LC-MS/MS in MRM mode19
Hook-effect in MAGLUMI immunoassay for serum anti-GAD antibodies in neurological disorders: When “wrong” matrix is the right choice19
Boron-doped diamond electrochemical biosensors18
Blood biomarkers for Alzheimer’s disease with the Lumipulse automated platform: Age-effect and clinical value interpretation18
Similar Ferroportin Q248H polymorphism prevalence in patients with Plasmodium falciparum malaria and control subjects in the low-endemic setting of Botswana18
Biological variation of thyroid function biomarkers over 24 hours18
Targeted plasma proteomic analysis uncovers a high-performance biomarker panel for early diagnosis of gastric cancer18
Lipocalin2 as a useful biomarker for risk stratification in patients with acute cholangitis: A single-center prospective and observational study18
Evaluation of a rapid immunochromatographic diagnostic test for heparin-induced thrombocytopenia: validation of delayed test and whole blood test18
Irisin in atherosclerosis18
Evaluation of thrombin generation assay in factor XI deficiency18
SLC37A4-CDG: New biochemical insights for an emerging congenital disorder of glycosylation with major coagulopathy17
The value of serum glial fibrillary acidic protein as a biomarker of astrogliosis in different neurological diseases17
Identification of a novel plasma metabolite panel as diagnostic biomarker for hepatocellular carcinoma17
Development and application of a novel aldehyde nanoparticle-based amplified luminescent proximity homogeneous assay for rapid quantitation of pancreatic stone protein17
Urinary iodine testing practices in China: Results of the 5-year external quality assessment program17
Non-coding RNA biomarkers in Alzheimer’s disease17
Diagnosis of patients with mucopolysaccharidosis type II via RNA sequencing17
Identification of of a PAX2 mutation from maternal mosaicism causes recurrent renal disorder in siblings17
Assay-Dependent Effects of EDTA Contamination on Magnesium and Iron17
Integrating multiplex PCR in fever clinics for acute respiratory pathogen-specific diagnosis17
Aptamer-based electrochemical biosensors for progesterone detection: Advancing point-of-care diagnostics17
Exploring strategies to rapidly identify false positives in high-sensitivity cardiac troponin I assay: A prospective study17
Comparison of digital PCR systems for the analysis of liquid biopsy samples of patients affected by lung and colorectal cancer17
Quantification of choline in serum and plasma using a clinical nuclear magnetic resonance analyzer17
Untargeted metabolomics analysis of the plasma metabolic signature of moderate-to-severe acne16
An accurate measurement method for serum homocysteine measurement by ID-LC/MS/MS and the application of external quality assessment16
The pentraxin family in autoimmune disease16
Recent advances in lateral flow assays for MicroRNA detection16
A retrospective analysis of 1600 infertility patients with azoospermia and severe oligozoospermia16
Potentiometric urea biosensors16
Metabolomics identifies metabolite markers in plasma and extracellular vesicles within plasma in patients with asthma16
Evaluating the effect of gestational diabetes mellitus on macrosomia based on the characteristics of oral glucose tolerance test16
Nanoparticle electrochemical biosensors for virus detection16
miRNA-based electrochemical biosensors for ovarian cancer16
Biological variation of methylmalonic acid in urine in spanish population16
Exosome biosensors for detection of liver cancer16
MicroRNA regulators of vascular pathophysiology in chronic kidney disease16
Resistin and omentin in breast cancer: A systematic review and meta-analysis16
Plasma protein biomarkers for long COVID-19: Predictors of symptom severity and mortality risk16
GLCCI1 gene body methylation in peripheral blood is associated with asthma and asthma severity16
Comment on ‘The diagnostic value of interleukin-36 cytokines in pleural effusions of varying etiologies’16
The assessment of endocannabinoids and N-acylethanolamines in human hair: Associations with sociodemographic and psychological variables15
Exploring the key factors of schizophrenia relapse by integrating LC-MS/1H NMR metabolomics and weighted correlation network analysis15
Comparison of clot waveform analysis with or without adjustment between prothrombin time and activated partial thromboplastin time assays to assess in vitro effects of direct oral anticoagulants15
Relationships among maternal monosomy X mosaicism, maternal trisomy, and discordant sex chromosome aneuploidies15
Pediatric reference values of NT-proBNP and Galectin-3 based on a French cohort15
A novel KCNQ2 missense variant in non-syndromic intellectual disability causes mild gain-of-function of Kv7.2 channel15
Cytomegalovirus antigen-specific multi-cytokine immune responses in patients with rheumatic diseases under different cytomegalovirus infection status: A case-control study15
Clinical implications of opioid parent-metabolite ratios15
Emergency severity level-3 patient flow based on point-of-care testing improves patient outcomes15
Association of lipoprotein(a) with left ventricular hypertrophy in patients with new-onset acute myocardial infarction: A large cross-sectional study15
Evaluation of iron metabolism in hospitalized COVID-19 patients15
A CD3G homozygous pathogenic variant in a Chinese child with lupus-like disease, autoimmune thyroiditis and immunodeficiency15
Proteomics of neuropsychiatric disorders14
MicroRNA and cyclooxygenase-2 in breast cancer14
Electrochemical biosensors in early leukemia detection14
Evaluating the utility of using glycated albumin in diagnosing dysglycemia among Saudis- A pilot study14
Distance changes of lymphocyte quantity and function in patients with COVID-1914
Liaison MeMed BV: A new approach for a quicker diagnosis between viral and bacterial infections in a cohort of pediatric patients14
Non-invasive fetal RHD genotyping in d- (RH:-1) patients with RHD genomic sequences: retrospective study over 11 years14
Evaluating the efficacy of a long-read sequencing-based approach in the clinical diagnosis of neonatal congenital adrenocortical hyperplasia14
Surface plasmon resonance: A promising approach for label-free early cancer diagnosis14
Large-scale retrospective analyses of the effect of iron deficiency anemia on hemoglobin A1c concentrations14
Application of neutrophil-to-lymphocyte ratio in the diagnosis of complicated pediatric appendicitis14
Leveraging machine learning to improve current diagnostic algorithms and laboratory stewardship14
Mild-to-moderate COVID-19 may affect nervous system function in convalescents14
Procalcitonin and transferrin as a survival markers of patients with COVID-1914
The clinical validation of a dried blood spot method for simultaneous measurement of cyclosporine A, tacrolimus, creatinine, and hematocrit14
A novel variant of the POLR3A gene in a patient with hypomyelinating POLR3-related leukodystrophy14
Advantages of the implementation of a second-tier test strategy in the newborn screening14
Overweight and obesity: The weight of genes14
The association of siMS and siMS risk scores with risk factors for cardiovascular events in university students with metabolic syndrome14
The role of laboratory diagnostics in determining the physical health of psychiatric inpatients14
Revolutionizing cell-based analyses: An electrochemical analysis platform with integrated incubator capabilities13
Challenges with sweat testing – A quality improvement initiative13
Association of HIV-1 Nef polymorphisms with coronary artery disease in HIV-positive patients13
W014 About a case of rhabdomyolysis in a 7 year-old child secondary to a deficiency of very long-chain acyl-coa dehydrogenase (VLCAD)13
T017 Analytical and clinical assessment of prostate specific antigen by chemiluminescence HISCL-5000 immunoassay13
Estimation of FGF-23 level in patients with chronic kidney disease with or without vitamin D supplementation13
Evaluation of the performance of biochemical ratios and albumin’s gradient in the etiological exploration of ascitic fluid13
Study of teratozoospermia in our population through analysis of seminal fluid in the assisted human reproduction unit of a Spanish referral hospital13
Novel biomarkers to improve diagnosis and monitor prognosis13
Utility of serum indices for predicting liver fibrosis13
The association between the PON1 genes rs662 and rs854560 and the metabolic syndrome in patients with obesity13
Editorial Board13
M122 Sample rejection of mixed body fluids for CSF identification – The utility of fluid protein concentration13
W157 Prostaglandin-D-synthase levels in cerebrospinal fluid associated with altered tau proteins in patients with suspected Alzheimer’s disease13
Plasma cellular prion protein concentrations correlate with severity and prognosis of aneurysmal subarachnoid hemorrhage13
Strategic collaboration to address nitrous oxide challenges: Establishment of an international consortium of experts13
Clinical performance evaluation of smartchek SARS-COV-2 detection kit and smartchek SARS-COV-2 fast detection kit for detection of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) in saliv13
Bacteriological profile and antimicrobial susceptibility patterns of organisms responsible for blood stream infections in intensive care unit patients13
Enhancing enteric pathogen detection: implementation and impact of multiplex PCR for improved diagnosis and surveillance13
Waste management in clinical laboratories13
Brucella outbreak linked to ice cream: A Lebanese case series13
W055 Serum erythroferrone in chronic kidney disease patients13
M200 Evaluation of eight commercially available clinical chemistry assays on the ALINITY® C system13
Risk stratification and predictive value of serum sodium fluctuation for adverse prognosis in acute coronary syndrome patients13
Impact of CSF collection volume in the accuracy of Alzheimer’s disease biomarker results13
Apolipoprotein C-III mucin core 2 O-Linked glycoforms: Hiding in plain sight13
Serologic profile of individuals who contracted COVID-19 despite triple vaccination13
Performance verification and reference interval establishment of serum/plasma aldosterone by a novel “sandwich” chemiluminescent immunoassay13
T104 An accuracy of blood glucose obtained from glucose meter [LDQUO]Standard Gluconavii® GDH Blood Glucose Meter[RDQUO] by testing with arterial and neonatal blood samples12
W224 Is there a relationship between seminal zinc concentration and sperm quality in overweight men?12
T181 Establishment of influence factors and ageing models for thyroid hormones in the elderly using real-world big data12
T021 Nagalase – New laboratory test for the discovery of malignancy and some serious viral diseases12
Stool antigen testing and serology’s accuracy in identifying helicobacter pylori infections in suspected patients12
Serum concentration of placental growth factor in pregnancy screening for placental dysfunction and low molecular weight heparin treatment12
Laboratory medicine residents in France − highly qualified, scarcely mobile12
Editorial board member, Aims and Scope, Publication Info.12
T129 Stability of arterial blood gases (ABG)12
W226 NGS-based pipeline for routine non-invasive preimplantation genetic assessment in IVF12
LIS requirements for laboratory management12
Clinical and genetic investigation in patients with permanent congenital hypothyroidism12
The biomarkers of oxidative stress – An effective tool for diagnosing COVID-19 patients and convalescents12
Deficiency or sufficiency? A five-year analysis of calcidiol levels across age groups in the Spanish population12
T079 High sensitive troponin assays in differentiating acute coronary syndrome from healthy individuals12
M052 Evaluation of extracellular fatty acid synthase and copeptin in obesity induced insulin resistance and metabolic syndrome12
T170 Three cases of endocrine immune-related adverse events caused by immune checkpoint inhibitor therapy12
T257 Blood coagulation testing and hematological features of thalassemia carriers in pregnant12
Use of point of care (POCT) c-reactive protein (CRP) to support antibiotic prescribing in primary care – Are they good enough? A review of performance on the Weqas POCT CRP programme12
Seroprevalence of antinuclear antibodies in patients with Hepatitis B12
Correlation between the levels of serum C-reactive protein and plasma glycated HbA1c in diabetic patients and non-diabetic individuals in the western parts of Nepal12
T201 The liver enzymes in patients with cirrhosis and hepatocellular carcinoma (HCC)12
Limitations of hemolysis-based correction for potassium measurement in hemolyzed whole blood samples11
MicroRNA biomarkers for predicting treatment response and resistance to bevacizumab in cancer11
Associations between polycythemia and cardiometabolic risk factors in middle-aged men11
At-admission HbA1c levels in hospitalized COVID-19 participants with and without known diabetes11
Lean adolescents with insulin resistance display higher angiopoietin like protein 3, ApoC-III and chylomicron remnant dyslipidemia11
Study of the impact of ClinGen Revisions on ACMG/AMP variant semi-automatic classification for Rare Diseases diagnosis11
Artificial intelligence in the clinical laboratory11
The role of tubulointerstitial markers in differential diagnosis and prognosis in patients with type 2 diabetes and biopsy proven diabetic kidney disease11
Quality management, ethical considerations, and emerging challenges in genomics and biobanking: A comprehensive review11
Enhancing breast cancer treatment through pharmacogenomics: A narrative review11
Neonatal myofibrillar myopathy type II associated with biallelic UNC-45B gene novel mutation and perinatal myasthenia as the core phenotype: A case report11
HDL subfractions determined by microfluidic chip electrophoresis predict the vulnerability of intracranial plaque: A HRMRI study11
Noninvasive fecal testing for colorectal cancer11
Analysis of two intestinal bacterial metabolites (trimethylamine N-oxide and phenylacetylglutamine) in human serum samples of patients with T2DM and AMI using a liquid chromatography tandem mass spect11
Validation of a liquid chromatography coupled to tandem mass spectrometry method for simultaneous quantification of tryptophan and 10 key metabolites of the kynurenine pathway in plasma and urine: App11
Targeting tumour markers in ovarian cancer treatment11
Association between apolipoprotein B/A1 and the risk of metabolic dysfunction associated fatty liver disease according to different lipid profiles in a Chinese population: A cross-sectional study11
Fragmentation of human cardiac troponin T after acute myocardial infarction11
Corrigendum to “The impact of triadimenol on male fertility: An in vitro study and molecular docking examination” [Reprod. Toxicol. 132 (2025) 108861]11
Metabolomic profiling of serum and tongue coating of pregnant women with intrahepatic cholestasis in pregnancy11
TQ-Oxime derivative: A promising therapeutic agent for U87 glioma cells assessment of cytotoxic and apoptotic properties11
Sclerostin in ankylosing spondylitis: A meta-analysis11
What do we need to obtain high quality circulating tumor DNA (ctDNA) for routine diagnostic test in oncology? – Considerations on pre-analytical aspects by the IFCC workgroup cfDNA11
A multi-test planning model for risk based statistical quality control strategies11
Expanding the clinical utility of reporter gene assay to infliximab biosimilars11
Biosensors and lateral flow immunoassays: Current state and future prospects11
0.16818499565125