Clinical and Experimental Immunology

Article	Citations
Vaccines for COVID-19	175
COVID-19 vaccine-readiness for anti-CD20-depleting therapy in autoimmune diseases	153
Using IL-2R/lymphocytes for predicting the clinical progression of patients with COVID-19	105
Innate immunity during SARS-CoV-2: evasion strategies and activation trigger hypoxia and vascular damage	78
Keratinocytes: innate immune cells in atopic dermatitis	76
IL-17 in inflammatory skin diseases psoriasis and hidradenitis suppurativa	69
Innate and adaptive immune responses to SARS-CoV-2 in humans: relevance to acquired immunity and vaccine responses	60
Roles of cytokines and T cells in the pathogenesis of myasthenia gravis	59
Establishing the prevalence of common tissue-specific autoantibodies following severe acute respiratory syndrome coronavirus 2 infection	50
Double-negative (DN) B cells: an under-recognized effector memory B cell subset in autoimmunity	43
MASP2 levels are elevated in thrombotic microangiopathies: association with microvascular endothelial cell injury and suppression by anti-MASP2 antibody narsoplimab	42
Comprehensive comparison between 222 CTLA-4 haploinsufficiency and 212 LRBA deficiency patients: a systematic review	40
Therapeutic vaccination for treatment of chronic hepatitis B	37
Characteristics and roles of severe acute respiratory syndrome coronavirus 2-specific antibodies in patients with different severities of coronavirus 19	34
The alternative complement pathway in ANCA-associated vasculitis: further evidence and a meta-analysis	33
Human CD4+ T cells specific for dominant epitopes of SARS-CoV-2 Spike and Nucleocapsid proteins with therapeutic potential	33
Does CCL19 act as a double-edged sword in cancer development?	30
Mycoplasma pneumoniae lipids license TLR-4 for activation of NLRP3 inflammasome and autophagy to evoke a proinflammatory response	30
The role of interleukin-18 in the diagnosis and monitoring of hemophagocytic lymphohistiocytosis/macrophage activation syndrome – a systematic review	29
Lymphocyte subsets early predict mortality in a large series of hospitalized COVID-19 patients in Spain	28
The effect of short-chain fatty acids on M2 macrophages polarizationin vitroandin vivo	28
MiR-223-3p inhibits inflammation and pyroptosis in monosodium urate-induced rats and fibroblast-like synoviocytes by targeting NLRP3	26
Reduced Siglec-7 expression on NK cells predicts NK cell dysfunction in primary hepatocellular carcinoma	25
Towards PET imaging of the dynamic phenotypes of microglia	25
Hypoxia regulates the differentiation and anti-tumor effector functions of γδT cells in oral cancer	25

Arthritis in systemic lupus erythematosus is characterized by local IL-17A and IL-6 expression in synovial fluid	25
A myriad of roles of dendritic cells in atherosclerosis	24
Clinical and neuroimaging findings in MOGAD–MRI and OCT	24
Sarcopenia and high NLR are associated with the development of hyperprogressive disease after second-line pembrolizumab in patients with non-small-cell lung cancer	24
Neutrophil-mediated mechanisms of damage and in-vitro protective effect of colchicine in non-vascular Behçet's syndrome	24
Outcomes following SARS-CoV-2 infection in patients with primary and secondary immunodeficiency in the UK	23
Reconnaissance of tumor immune microenvironment spatial heterogeneity in metastatic renal cell carcinoma and correlation with immunotherapy response	23
Extracellular vesicles containing PD-L1 contribute to CD8+ T-cell immune suppression and predict poor outcomes in small cell lung cancer	23
Endothelial-to-mesenchymal transition in systemic sclerosis	22
Rheumatoid arthritis synovial microenvironment induces metabolic and functional adaptations in dendritic cells	22
IL-2-based approaches to Treg enhancement	21
Spliced HLA-bound peptides: a Black Swan event in immunology	21
Immunological findings in patients with migraine and other primary headaches: a narrative review	20
Gut microbiome and autoimmune disorders	20
Mucosal-associated invariant T (MAIT) cells are activated in the gastrointestinal tissue of patients with combination ipilimumab and nivolumab therapy-related colitis in a pathology distinct from ulce	19
Engineering of chimeric natural killer cell receptors to develop precision adoptive immunotherapies for cancer	19
Analysis of T and NK cell subsets in the Sicilian population from young to supercentenarian: The role of age and gender	19
Neuroinflammation and immunoregulation in glioblastoma and brain metastases: Recent developments in imaging approaches	19
Type I interferon regulates cytokine-delayed neutrophil apoptosis, reactive oxygen species production and chemokine expression	19
TREC and KREC profiling as a representative of thymus and bone marrow output in patients with various inborn errors of immunity	18
Whole blood interleukin-2 release test to detect and characterize rare circulating gluten-specific T cell responses in coeliac disease	18
Exhausted T cells in systemic lupus erythematosus patients in long-standing remission	18
The rise of complement in ANCA-associated vasculitis: from marginal player to target of modern therapy	18
Bronchiectasis is associated with delayed diagnosis and adverse outcomes in the New Zealand Common Variable Immunodeficiency Disorders cohort study	17
Correlations of the expression of γδ T cells and their co-stimulatory molecules TIGIT, PD-1, ICOS and BTLA with PR and PIBF in the peripheral blood and decidual tissues of women with unexplained recur	16
Complement activation in patients with immune thrombocytopenic purpura according to phases of disease course	16
Inborn errors of human IKAROS: LOF and GOF variants associated with primary immunodeficiency	16
Immunotherapeutic targeting of activating natural killer cell receptors and their ligands in cancer	16
Generation of a novel CD30+ B cell subset producing GM-CSF and its possible link to the pathogenesis of systemic sclerosis	16
Variety of endosomal TLRs and Interferons (IFN-α, IFN-β, IFN-γ) expression profiles in patients with SLE, SSc and MCTD	16
Emerging patterns of regulatory T cell function in tuberculosis	16
Exosomal PD-L1 predicts response with immunotherapy in NSCLC patients	15
Treg specialization and functions beyond immune suppression	15
The regulatory role of eosinophils in viral, bacterial, and fungal infections	15
Autophagy modulation in multiple sclerosis and experimental autoimmune encephalomyelitis	15
Patho-immunological mechanisms of vitiligo: the role of the innate and adaptive immunities and environmental stress factors	14
Metabolites as drivers and targets in rheumatoid arthritis	14
Adoptive transfer of immunomodulatory M2 macrophages suppresses experimental autoimmune encephalomyelitis in C57BL/6 mice via blockading NF-κB pathway	14
Magnetic resonance imaging in neuromyelitis optica spectrum disorder	14
Recombinant Mycobacterium bovis BCG is a promising platform to develop vaccines against Trypansoma cruzi infection	13
Identification of peripheral CD154+ T cells and HLA-DRB1 as biomarkers of acute cellular rejection in adult liver transplant recipients	13
Interleukin-35 has a tumor-promoting role in hepatocellular carcinoma	13
Accumulation of amyloid beta in human glioblastomas	13
Simultaneous testing of immunological sensitization to multiple antigens in sarcoidosis reveals an association with inorganic antigens specifically related to a fibrotic phenotype	13
Th22 response induced byMycobacterium tuberculosisstrains is closely related to severity of pulmonary lesions and bacillary load in patients with multi-drug-resistant tuberculosis	13
Bone marrow-derived mesenchymal stem cells inhibit CD8+ T cell immune responses via PD-1/PD-L1 pathway in multiple myeloma	13
Cladribine modifies functional properties of microglia	13
Immunological basis of early clearance ofMycobacterium tuberculosisinfection: the role of natural killer cells	13
Regulatory T-cell therapy approaches	13
Clinical, functional and genetic characterization of 16 patients suffering from chronic granulomatous disease variants – identification of 11 novel mutations inCYBB	13

Increased expression of CXCL2 in ACPA-positive rheumatoid arthritis and its role in osteoclastogenesis	13
B cell contribution to immunometabolic dysfunction and impaired immune responses in obesity	12
Adaptive immune system in pulmonary sarcoidosis—Comparison of peripheral and alveolar biomarkers	12
Relationship between natural and infection-induced antibodies in systemic autoimmune diseases (SAD): SLE, SSc and RA	12
SARS-CoV-2 vaccine responses following CD20-depletion treatment in patients with haematological and rheumatological disease: a West Midlands Research Consortium study	12
Antibodies as biomarkers for cancer risk: a systematic review	12
Characterization of circulating immune cells in acute Kawasaki disease suggests exposure to different antigens	12
Combination of pegylated interferon-alpha and nucleos(t)ide analogue treatment enhances the activity of natural killer cells in nucleos(t)ide analogue experienced chronic hepatitis B patients	12
Lymphadenopathy at the crossroad between immunodeficiency and autoinflammation: An intriguing challenge	12
Pathological role of excessive DNA as a trigger of keratinocyte proliferation in psoriasis	12
Isotype selection for antibody-based cancer therapy	11
Gut microbiome alterations in type 1 autoimmune pancreatitis after induction of remission by prednisolone	11
FAM96A knock-out promotes alternative macrophage polarization and protects mice against sepsis	11
Activated inducible co-stimulator-positive programmed cell death 1-positive follicular helper T cells indicate disease activity and severity in ulcerative colitis patients	11
Impaired function of PD-1+ follicular regulatory T cells in systemic lupus erythematosus	11
Immune checkpoint inhibitors and cellular treatment for lymphoma immunotherapy	11
Impairment of antigen-presenting function of peripheral γδ T cells in patients with sepsis	11
Mechanisms of induction of regulatory B cells in the tumour microenvironment and their contribution to immunosuppression and pro-tumour responses	11
E3 ubiquitin ligase Casitas B lineage lymphoma-b and its potential therapeutic implications for immunotherapy	11
Factors determining COVID-19 pneumonia severity in a country with routine BCG vaccination	11
The clinical, molecular, and therapeutic features of patients with IL10/IL10R deficiency: a systematic review	11
Inactivation of TMEM106A promotes lipopolysaccharide-induced inflammation via the MAPK and NF-κB signaling pathways in macrophages	11
Comprehensive flow cytometric reference intervals of leukocyte subsets from six study centers across Europe	11
A close-up on the expanding landscape of CD21–/low B cells in humans	11
Rapamycin-based graft-versus-host disease prophylaxis increases the immunosuppressivity of myeloid-derived suppressor cells without affecting T cells and anti-tumor cytotoxicity	11
Inborn errors of immunity with loss- and gain-of-function germline mutations in STAT1	10
Clinical and laboratory findings in patients with leukocyte adhesion deficiency type I: A multicenter study in Turkey	10
Hypomethylation of Notch1 DNA is associated with the occurrence of uveitis	10
E3 ubiquitin ligases STUB1/CHIP contributes to the Th17/Treg imbalance via the ubiquitination of aryl hydrocarbon receptor in rheumatoid arthritis	10
Altered inflammasome activation in neonatal encephalopathy persists in childhood	10
Endothelial cells response to neutrophil-derived extracellular vesicles miRNAs in anti-PR3 positive vasculitis	10
Low-density neutrophils in chronic graft versus host disease (cGVHD) are primarily immature CD10– and enhance T cell activation	10
Immune checkpoint expression on peripheral cytotoxic lymphocytes in cervical cancer patients: moving beyond the PD-1/PD-L1 axis	10
Autoantibodies associated with primary biliary cholangitis are common among patients with systemic lupus erythematosus even in the absence of elevated liver enzymes	10
Associations between clinical features and therapy with macrophage subpopulations and T cells in inflammatory lesions in the aorta from patients with Takayasu arteritis	10
Identification of a unique anti-Ro60 subset with restricted serological and molecular profiles	9
Body mass index and adipokines/cytokines dysregulation in systemic sclerosis	9
Intravenous immunoglobulin induces IgG internalization by tolerogenic myeloid dendritic cells that secrete IL-10 and expand Fc-specific regulatory T cells	9
The effects of advanced maternal age on T-cell subsets at the maternal–fetal interface prior to term labor and in the offspring: a mouse study	9
Immunodeficiency (CVID and CD4 lymphopenia) is associated with a high risk of malignancy among adults with primary immune deficiency	9
Key role of macrophages in tolerance induction via T regulatory type 1 (Tr1) cells	9
Cytokine production by human B cells: role in health and autoimmune disease	9
Association of the polymorphism of the Toll-like receptor (TLR)-3 and TLR-9 genes with hepatitis C virus-specific cell-mediated immunity outcomes among Egyptian health-care workers	9
CD21low B cells are predictive markers of new digital ulcers in systemic sclerosis	9
Kidney infiltrating NK cells and NK-like T-cells in lupus nephritis: presence, localization, and the effect of immunosuppressive treatment	9
Potential role of BAY11-7082, a NF-κB blocker inhibiting experimental autoimmune encephalomyelitis in C57BL/6J mice via declining NLRP3 inflammasomes	9
RORγt+Foxp3+ regulatory T cells in the regulation of autoimmune arthritis	9
Neutrophil elastase and endogenous inhibitors in Behçet's disease saliva	9
Evaluation of QuantiFERON SARS-CoV-2 interferon-γ release assay following SARS-CoV-2 infection and vaccination	9
Baicalein inhibits macrophage lipid accumulation and inflammatory response by activating the PPARγ/LXRα pathway	9
IRF5 regulates airway macrophage metabolic responses	9
Neutrophils in autoimmunity: when the hero becomes the villain	9
Seroconversion following COVID-19 vaccination: can we optimize protective response in CD20-treated individuals?	9
Inflammatory cytokine responses in children with asymptomatic malaria infection living in rural, semi-urban and urban areas in south-eastern Gabon	9
Kinetic studies of galectin-10 release from eosinophils exposed to proliferating T cells	8
Heparin affects the induction of regulatory T cells independent of anti-coagulant activity and suppresses allogeneic immune responses	8
Immunopathology of the optic nerve in multiple sclerosis	8
MOSPD2 is a therapeutic target for the treatment of CNS inflammation	8
Reference range of naïve T and T memory lymphocyte subsets in peripheral blood of healthy adult	8
Different subclasses and isotypes of antibodies against phosphorylcholine in haemodialysis patients: association with mortality	8
HBV-specific CD8 T cells present higher TNF-α expression but lower cytotoxicity in hepatocellular carcinoma	8
Gingival transcriptomics of follicular T cell footprints in progressing periodontitis	8
Follicular helper and follicular regulatory T cell subset imbalance is associated with higher activated B cells and abnormal autoantibody production in primary anti-phospholipid syndrome patients	8
Not too little, not too much: the impact of mutation types in Wiskott-Aldrich syndrome and RAC2 patients	8
Lymphocyte modulation by tofacitinib in patients with rheumatoid arthritis	8
The potential for treg-enhancing therapies in nervous system pathologies	8
Increased TNF-α production in response to IL-6 in patients with systemic inflammation without infection	8
The autoimmune encephalitis-related cytokine TSLP in the brain primes neuroinflammation by activating the JAK2-NLRP3 axis	8
Is gene panel sequencing more efficient than clinical-based gene sequencing to diagnose autoinflammatory diseases? A randomized study	8
Citrullinated inter-alpha-trypsin inhibitor heavy chain 4 in arthritic joints and its potential effect in the neutrophil migration	8
Relapse rate and renal prognosis in ANCA-associated vasculitis according to long-term ANCA patterns	7
LncRNA MIR155HG functions as a ceRNA of miR-223-3p to promote cell pyroptosis in human degenerative NP cells	7
Immunorelated gene polymorphisms associated with acute myeloid leukemia	7
Bacillus Calmette–Guérin Tokyo-172 vaccine provides age-related neuroprotection in actively induced and spontaneous experimental autoimmune encephalomyelitis models	7
Peroxiredoxins are involved in the pathogenesis of multiple sclerosis and neuromyelitis optica spectrum disorder	7
Single-cell transcriptome analysis reveals endometrial immune microenvironment in minimal/mild endometriosis	7
A hyperacute immune map of ischaemic stroke patients reveals alterations to circulating innate and adaptive cells	7
Late diagnosis of chronic granulomatous disease	7
Tofacitinib treatment modulates the levels of several inflammation-related plasma proteins in rheumatoid arthritis and baseline levels of soluble biomarkers associate with the treatment response	7
Microvesicles in active lupus nephritis show Toll-like receptor 9-dependent co-expression of galectin-3 binding protein and double-stranded DNA	7

The ups and downs of STAT3 function: too much, too little and human immune dysregulation	7
Suppressor of cytokine signaling 1 inhibits the maturation of dendritic cells involving the nuclear factor kappa B signaling pathway in the glioma microenvironment	7
Nuclear factor kappa B inhibitor suppresses experimental autoimmune neuritis in mice via declining macrophages polarization to M1 type	7
Mediterranean fever gene variants modify clinical phenotypes of idiopathic multi-centric Castleman disease	7
A single-center pilot study in Malaysia on the clinical utility of whole-exome sequencing for inborn errors of immunity	7
CD155 expression impairs anti-PD1 therapy response in non-small cell lung cancer	7
The longitudinal loss of islet autoantibody responses from diagnosis of type 1 diabetes occurs progressively over follow-up and is determined by low autoantibody titres, early-onset, and genetic varia	7
Macrophages in ovarian cancer and their interactions with monoclonal antibody therapies	7
Leukocyte immunoglobulin-like receptor A3 is increased in IBD patients and functions as an anti-inflammatory modulator	7
Non-organ-specific autoimmunity in adult 47,XXY Klinefelter patients and higher-grade X-chromosome aneuploidies	7
Behçet disease, new insights in disease associations and manifestations: a next-generation sequencing study	7
Whole-exome sequencing of T-B+ severe combined immunodeficiency in Egyptian infants, JAK3 predominance and novel variants	7
Leonurus sibiricus root extracts decrease airway remodeling markers expression in fibroblasts	7
Clinical features and nasal inflammation in asthma and allergic rhinitis	7
The role of lipid metabolism in shaping the expansion and the function of regulatory T cells	7
The AHNAK induces increased IL-6 production in CD4+ T cells and serves as a potential diagnostic biomarker for recurrent pregnancy loss	7
CMV infection combined with acute GVHD associated with poor CD8+ T-cell immune reconstitution and poor prognosis post-HLA-matched allo-HSCT	7
Altered distributions in circulating follicular helper and follicular regulatory T cells accountable for imbalanced cytokine production in multiple sclerosis	7
Circulating regulatory T cells in adult-onset Still's disease: Focusing on their plasticity and stability	7