OOIR: Observatory of International Research

Papers

(The TQCC of Clinical and Experimental Immunology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Issue Information	63
The hyper-expression of NLRP4 characterizes the occurrence of macrophage activation syndrome assessing STING pathway in adult-onset Still’s disease	62
Understanding immunological insights of liver transplantation: a practice for attaining operational tolerance	57
Expression levels of cellular inhibitor of apoptosis proteins and colitogenic cytokines are inversely correlated with the activation of interferon regulatory factor 4	54
Anti-CD47 antibody synergizes with cisplatin against laryngeal cancer by enhancing phagocytic ability of macrophages	52
Issue Information	43
Gut microbiome and autoimmune disorders	43
Issue Information	38
Issue Information	37
Decoding the proregenerative competence of regulatory T cells through complex tissue regeneration in zebrafish	36
Mouse CD8+ T cell subsets differentially generate IL-17-expressing cells in the colon epithelium and lamina propria	36
Cytokine production by human B cells: role in health and autoimmune disease	36
Correction to: Cisplatin-mediated down-regulation of miR-145 contributes to up-regulation of PD-L1 via the c-Myc transcription factor in cisplatin-resistant ovarian carcinoma cells	35
Characterization of T-bet expressing B cells in lupus patients indicates a putative prognostic and therapeutic value of these cells for the disease	35
COVID-19 infection and vaccination in immunodeficiency	32
Neutrophil extracellular traps are involved in the occurrence of interstitial lung disease in a murine experimental autoimmune myositis model	32
The potential for Treg-enhancing therapies in tissue, in particular skeletal muscle, regeneration	31
Clinical and experimental treatment of primary humoral immunodeficiencies	30
B cells recruitment promotes M2 macrophage polarization to inhibit inflammation during wound healing	29
Nck1 regulates the in vitro development of human regulatory T cells through AKT pathway	29
Lymphocyte modulation by tofacitinib in patients with rheumatoid arthritis	28
Low-density neutrophils in chronic graft versus host disease (cGVHD) are primarily immature CD10– and enhance T cell activation	28
A novel mast cell-dependent allergic peritonitis model	27
Improved function and balance in T cell modulation by endothelial cells in young people	26
Circulating regulatory T cells in adult-onset Still's disease: Focusing on their plasticity and stability	26

Intravenous immunoglobulin and the current risk of moderate and severe anaphylactic events, a cohort study	25
RORγt+Foxp3+ regulatory T cells in the regulation of autoimmune arthritis	25
Extracellular vesicles containing PD-L1 contribute to CD8+ T-cell immune suppression and predict poor outcomes in small cell lung cancer	25
Leptin-reactive antibodies are distinctly correlated with body composition parameters and metabolic risk indexes in children and adolescents	24
Characterization of allergic inflammation in chronic uterine cervicitis	24
Outcomes following SARS-CoV-2 infection in patients with primary and secondary immunodeficiency in the UK	23
The PPAR-γ agonist pioglitazone exerts proinflammatory effects in bronchial epithelial cells during acute Pseudomonas aeruginosa pneumonia	23
Panobinostat enhances NK cell cytotoxicity in soft tissue sarcoma	22
Identification of ANXA2 on epithelial cells as a new receptor for secretory IgA using immunoprecipitation and mass spectrometry	22
Differentiation of circulating monocytes into macrophages with metabolically activated phenotype regulates inflammation in dyslipidemia patients	21
Signals from the TAFA4-PTEN-PU.1 axis alleviate nasal allergy by modulating the expression of FcεRI in mast cells	19
Enhancing and stabilization of cord blood regulatory T-cell suppressive function by human mesenchymal stem cell (MSC)-derived exosomes	19
Anti-glutathione S-transferase omega 1-1 (GSTO1-1) antibodies are increased during acute and chronic inflammation in humans	18
Tofacitinib treatment modulates the levels of several inflammation-related plasma proteins in rheumatoid arthritis and baseline levels of soluble biomarkers associate with the treatment response	18
Upregulated expression of substance P and NK1R in blood monocytes and B cells of patients with allergic rhinitis and asthma	18
Group B Streptococcus (GBS) colonization is dynamic over time, whilst GBS capsular polysaccharides-specific antibody remains stable	18
Kinetics of immune responses to SARS-CoV-2 proteins in individuals with varying severity of infection and following a single dose of the AZD1222	18
The yin and the yang of early classical pathway complement disorders	18
Gingival transcriptomic patterns of macrophage polarization during initiation, progression, and resolution of periodontitis	17
miR-132-3p regulates antibody-mediated complement-dependent cytotoxicity in colon cancer cells by directly targeting CD55	17
What do we know about co-stimulatory and co-inhibitory immune checkpoint signals in ankylosing spondylitis?	17
Secretory-IgA binding to intestinal microbiota attenuates inflammatory reactions as the intestinal barrier of preterm infants matures	16
Antinuclear antibody (ANA) status predicts immune-related adverse events in liver cancer patients undergoing anti-PD-1 therapy	16
Plasmablasts in previously immunologically naïve COVID-19 patients express markers indicating mucosal homing and secrete antibodies cross-reacting with SARS-CoV-2 variants and other beta-coronaviruses	16
Protective and pathogenic functions of innate lymphoid cells in transplantation	15
Identification of differences in the magnitude and specificity of SARS-CoV-2 nucleocapsid antibody responses in naturally infected and vaccinated individuals	15
Unconventional T cells in chronic disease and as targets of therapy	14
Destined for the intestine: thymic selection of TCRαβ CD8αα intestinal intraepithelial lymphocytes	14
Human in vitro-induced IL-17A+ CD8+ T-cells exert pro-inflammatory effects on synovial fibroblasts	13
Transcriptome profiling of regulatory T cells from children with transient hypogammaglobulinemia of infancy	13
Altered CD226/TIGIT expressions were associated with NK phenotypes in primary antiphospholipid syndrome and affected by IL-4/JAK pathway	13
IAPs and RIPK1 mediate LPS-induced cytokine production in healthy subjects and Crohn’s disease	13
Conventional and unconventional T-cell responses contribute to the prediction of clinical outcome and causative bacterial pathogen in sepsis patients	13
Disease activity in chronic inflammatory demyelinating polyneuropathy: association between circulating B-cell subsets, cytokine levels, and clinical outcomes	13
Correction to: Type 1 interferon auto-antibodies are elevated in patients with decompensated liver cirrhosis	13
The alteration of mucosal bile acid profile is associated with nerve growth factor expression in mast cells and bowel symptoms in diarrhea-predominant irritable bowel syndrome	12
Tubulin beta 5 is not the target of antineutrophil antibodies in primary sclerosing cholangitis	12
Genomic testing identifies monogenic causes in patients with very early-onset inflammatory bowel disease: a multicenter survey in an Iranian cohort	12
Targeting T-bet expressing B cells for therapeutic interventions in autoimmunity	12
Follow-up of immune response in patients with common variable immunodeficiency following SARS-CoV-2 vaccination	12
Defining the cross-reactivity between peanut allergens Ara h 2 and Ara h 6 using monoclonal antibodies	12
Unexplained fever with consumptive syndrome in the elderly: two cases of VEXAS syndrome with inflammasome dysregulation	12
Beta-adrenergic stimulation promotes an endoplasmic reticulum stress-dependent inflammatory program in salivary gland epithelial cells	12
Regulatory T-cell frequency and function in acute myocardial infarction patients and its correlation with ventricular dysfunction	12
Seronegative NMOSD patients display distinctive peripheral blood T-cell subset frequencies	12
Splenectomy at early stage of autoimmune arthritis delayed inflammatory response and reduced joint deterioration in mice	12
Dysregulated lipid metabolism networks modulate T-cell function in people with relapsing-remitting multiple sclerosis	11
Regulatory T cells in inflamed liver are dysfunctional in murine primary biliary cholangitis	11
Multi-dimensional analysis of B cells reveals the expansion of memory and regulatory B-cell clusters in humans living in rural tropical areas	11
Inflammatory cytokine responses in children with asymptomatic malaria infection living in rural, semi-urban and urban areas in south-eastern Gabon	11

Investigating T-cell-derived extracellular vesicles as biomarkers of disease activity, axonal injury, and disability in multiple sclerosis	11
Antigen-specific T-cell frequency and phenotype mirrors disease activity in DRB1*04:04+ rheumatoid arthritis patients	11
Efficacy of anti-programmed cell death protein 1 monoclonal antibody combined with bevacizumab and/or Pseudomonas aeruginosa injection in transplanted tumor of mouse forestomach carcinoma cell	11
Neutrophil-mediated mechanisms of damage and in-vitro protective effect of colchicine in non-vascular Behçet's syndrome	11
Identification of biomarkers for disease severity in nasopharyngeal secretions of infants with upper or lower respiratory tract viral infections	11
Human FCHO1 deficiency: review of the literature and additional two cases	11
Human genetic and immunological determinants of SARS-CoV-2 infection and multisystem inflammatory syndrome in children	11
Bacillus Calmette-Guerin (BCG) induces superior anti-tumour responses by Vδ2+ T cells compared with the aminobisphosphonate drug zoledronic acid	11
CD3 downregulation identifies high-avidity human CD8 T cells	11
Human B-cell subset identification and changes in inflammatory diseases	11
Effect of the ketone beta-hydroxybutyrate on markers of inflammation and immune function in adults with type 2 diabetes	11
Identification of novel NFKB1 and ICOS frameshift variants in patients with CVID	10
Unveiling WHIM syndrome: Mavorixafor's Emerging Role in Immune Restoration and Therapy	10
Expression of Concern: Therapeutic effect of farnesylthiosalicylic acid on adjuvant-induced arthritis through suppressed release of inflammatory cytokines	10
Deciphering the Plasmodium falciparum malaria-specific CD4+ T-cell response: ex vivo detection of high frequencies of PD-1+TIGIT+ EXP1-specific CD4+ T cells using a novel HLA-DR11-restri	10
	10
Molecular neuroimaging of inflammation in HIV	10
Functional validation of a novel STAT3 ‘variant of unknown significance’ identifies a new case of STAT3 GOF syndrome and reveals broad immune cell defects.	10
The small molecule inhibitor 3PO is a modulator of neutrophil metabolism, ROS production and NET release	10
Corrigendum	10
Imaging immune responses in neuroinflammatory diseases	10
Patho-immunological mechanisms of vitiligo: the role of the innate and adaptive immunities and environmental stress factors	10
Neuro-Behçet’s disease: an update of clinical diagnosis, biomarkers, and immunopathogenesis	10
Macrophages in ovarian cancer and their interactions with monoclonal antibody therapies	10
A multi-centre UK-based survey on angioedema secondary to acquired C1 inhibitor deficiency	10
Exosomal PD-L1 predicts response with immunotherapy in NSCLC patients	10
Human CD4+ T cells specific for dominant epitopes of SARS-CoV-2 Spike and Nucleocapsid proteins with therapeutic potential	9
Polyfunctional donor-reactive T cells are associated with acute T-cell-mediated rejection of the kidney transplant	9
Effect and mechanisms of dexmedetomidine combined with macrophage migration inhibitory factor inhibition on the expression of inflammatory factors and AMPK in mice	9
Clinical features, diagnosis, and management of pembrolizumab-induced myasthenia gravis	9
Dissecting T-cell heterogeneity in esophageal squamous cell carcinoma reveals the potential role of LAIR2 in antitumor immunity	9
Type I Interferon Signature: a Quantitative Standardized Method for Clinical Application	9
The effect of immunomodulatory therapy with recombinant human interferon alpha-2β on blood cytokine levels in children with recurrent episodes of acute obstructive bronchitis	9
Differentiating between activation via the lectin or the classical complement pathway in patients with systemic lupus erythematosus	9
Diagnostic significance of blood lymphocyte activation markers in pre-eclampsia	8
Plasma pentraxin 3 in idiopathic inflammatory myopathies: a possible new biomarker of disease activity	8
Myelin oligodendrocyte glycoprotein antibody and N-methyl-d-aspartate receptor antibody overlapping syndrome: insights from the recent case reports	8
Effector CD4+ T-cell subsets in Takayasu arteritis—differences between the peripheral blood and the aorta	8
Autoantibodies to beta tubulin in autoimmune liver diseases—Relation to pANCA and clinical relevance	8
Exploring S100A8/A9, neopterin, and MMP3 in familial Mediterranean fever	8
Investigating immune profile by CyTOF in patients with eosinophilic esophagitis after treatment with orodispersible budesonide	8
Aberrant B-cell activation and B-cell subpopulations in rheumatoid arthritis: analysis by clinical activity, autoantibody seropositivity, and treatment	8
Heterogeneity in RAG1 and RAG2 deficiency: 35 cases from a single-centre	8
Leucine-rich repeat kinase 2 promotes the development of experimental severe acute pancreatitis	8
Cultured lymphocytes’ mitochondrial genome integrity is not altered by cladribine	8
Gender-affirming hormone therapy and autoimmunity: new insights from a 3-year follow-up study	8
Tuning the potency and selectivity of ImmTAC molecules by affinity modulation	8
A homogeneous bioluminescent inhibition immunoassay to detect anti-interferon gamma antibodies	8
IL-38 alleviates airway remodeling in chronic asthma via blocking the profibrotic effect of IL-36γ	8
MASP2 inhibition by narsoplimab suppresses endotheliopathies characteristic of transplant-associated thrombotic microangiopathy:in vitroandex vivoevidence	8
IL-21, not IL-17A, exacerbates murine primary biliary cholangitis	8
Anti-TPO-mediated specific features of the placenta immunohistochemical profile and possible mechanisms for fetal loss	8
Immunological dynamic characteristics in acute myeloid leukemia predict the long-term outcomes and graft-versus host-disease occurrences post-transplantation	8
Gene expression analysis revealed downregulation of complement receptor 1 in clonal B cells in cold agglutinin disease	8
Immune profiling reveals umbilical cord blood mononuclear cells from South India display an IL-8 dominant, CXCL-10 deficient polyfunctional monocyte response to pathogen-associated molecular patterns	8
C/EBPε and its acetylation in PMN enhance the tolerance to trauma	8
Allergens induce upregulated IL-18 and IL-18Rα expression in blood Th2 and Th17 cells of patients with allergic asthma	7
Investigating Concomitant RAG-2 and LRBA Mutations in SCID and Autoimmunity	7
Diagnostic accuracy of saliva-based testing as a Vibrio cholerae surveillance tool among naturally infected patients	7
My highlights as Editor-in-Chief of Clinical & Experimental Immunology, 2017–2024	7
Dynamic mRNA expression of donor-derived activating KIR genes and their significant effects on clinical outcome after haematopoietic stem cell transplantation	7
Clinical and neuroimaging findings in MOGAD–MRI and OCT	7
Unveiling immunological signatures and predictors of response to immunosuppressive therapy in acquired aplastic anemia	7
Expression of sPD-L1 levels in an ex vivo liver perfusion model	7
Reduced response to SARS-CoV-2 vaccination is associated with impaired immunoglobulin class switch recombination in SLE patients	7
The prevalence of anti-neurofascin-155 antibodies in patients with neuromyelitis optica spectrum disorders	7
T cell activator-carrying extracellular vesicles induce antigen-specific regulatory T cells	7
Chronic bacterial pulmonary infections in advanced cystic fibrosis differently affect the level of sputum neutrophil elastase, IL-8 and IL-6	7
Implementing distinct spatial proteogenomic technologies: opportunities, challenges, and key considerations	7
Environmental pollutant 3-methyl-4-nitrophenol promotes the expression of oncostatin M to exacerbate airway allergic inflammation	7
Amlexanox targeted inhibition of TBK1 regulates immune cell function to exacerbate DSS-induced inflammatory bowel disease	7
The B-cells paradigm in systemic sclerosis: an update on pathophysiology and B-cell-targeted therapies	7
Differences in cytokine and chemokine profiles in cerebrospinal fluid caused by the etiology of cryptococcal meningitis and tuberculous meningitis in HIV patients	7
Altered distributions in circulating follicular helper and follicular regulatory T cells accountable for imbalanced cytokine production in multiple sclerosis	7
CpG oligodeoxynucleotide-coated chitosan nanoparticles enhance macrophage proinflammatory phenotype in vitro	7