Clinical Biochemistry

Article	Citations
Editorial Board	88
Relationship between analytical imprecision and coefficient of determination (R2) of the calibration curve	77
Quantitative evaluation of adalimumab and anti-adalimumab antibodies in sera using a surface plasmon resonance biosensor	71
In vivo and in vitro relationship between ionized magnesium and ionized calcium	61
Establishing age-stratified red blood cell fatty acid reference ranges using model-based clustering and iterative application of the harris-boyd method	26
Clinical impact of PTEN rs701848 as a predictive marker for breast cancer	23
Editorial Board	22
Validation of glucose and lactate in cerebrospinal fluid (CSF) on a Radiometer blood gas analyzer ABL90 Flex plus	22
Difference- and regression-based approaches for detection of bias	21
Age- and ethnicity-related reference intervals for serum vitamin B12	21
Serological proteomic profiling uncovered CDK5RAP2 as a novel marker in benign prostatic hyperplasia	21
Clinical laboratory test utilization of CSF oligoclonal bands and IgG index in a tertiary pediatric hospital	20
The importance of SII and FIB-4 scores in predicting mortality in idiopathic pulmonary fibrosis patients	20
New solutions to old problems: A practical approach to identify samples with intravenous fluid contamination in clinical laboratories	20
Salivary antibodies are detected with a commercial anti-SARS-CoV-2 assay only after two doses of vaccine using serum thresholds	19
External validation of the clinical chemistry score	19
Serum free light chain reference intervals in an Optilite and their influence on clinical guidelines	19
Dealing with redundant gamma glutamyl transpeptidase in primary care, when requested along with alkaline phosphatase	18
Comparison of glomerular filtration rate estimating formulas among Japanese adults without kidney disease	17
Benign transient hyperphosphatasemia: Two case reports	17
Serological detection of antibodies to the SARS-CoV-2 nucleocapsid protein from dried blood spots	17
Effective stewardship strategies to enhance appropriateness of refer-out test requests in a Canadian tertiary centre laboratory	16
IgG4-IgE complex interferes with measurement of IgE concentration	16
Unexpected discovery of CRP analytical interference: A case report	16
Cardiac biomarkers and CT coronary angiography for the assessment of coronary heart disease	15

Inflammatory markers and their association with preeclampsia among pregnant women: A systematic review and meta-analysis	15
Reply to Letter to the Editor “The importance of SII and FIB-4 scores in predicting mortality in idiopathic pulmonary fibrosis patients”	15
Biotinidase activity is affected by both seasonal temperature and filter collection cards	15
Oral glucose tolerance test to diagnose gestational diabetes mellitus: Impact of variations in specimen handling	15
Considerations for understanding protein measurements: Identification of formation, degradation and more pathological relevant epitopes	14
Circulating miRNA and circulating tumor DNA application as liquid biopsy markers in gastric cancer	14
A new pattern of citrullinated peptides improves the sensitivity for diagnosing rheumatoid arthritis	14
What to do when the gold standard isn’t accessible?	13
Hydroxocobalamin does not interfere with high-sensitivity cardiac troponin T assay	13
Measuring copeptin, a surrogate for vasopressin in patients with hypertension – Can it identify those who are volume Responsive?	13
Comparison of two (data mining) indirect approaches for between-subject biological variation determination	13
Mid-regional pro-atrial natriuretic peptide levels before and after hemodialysis predict long-term prognosis	13
Luteinizing hormone (LH) formed a complex with an immunoglobulin G caused abnormally high levels of LH: A case report	13
Hb Maruchi [α165 (E14) Ala>Pro; HBA1: c.196G>C]: A new thalassemia hemoglobinopathy related to the alpha1 globin gene	13
Comparison of blood collection tubes for 29 biochemical analytes in pediatric patients with central venous catheters	13
Interference of anti-streptavidin antibodies: More common than we thought? In relation to six confirmed cases	13
Evaluation of the stability of fecal immunochemical test specimens	13
How far is the goal of applying β-amyloid in cerebrospinal fluid for clinical diagnosis of Alzheimer’s disease with standardization of measurements?	12
Factors to consider with estimated low-density lipoprotein cholesterol using the new Sampson/NIH equation	12
Editorial Board	12
Ex vivo hemolysis: Three cases demonstrating mechanically-induced hemolysis from the extracorporeal circuit during hemodialysis	11
Are discordant cTnI results detected in an analytical comparison clinically irrelevant?	11
Freelite and Kloneus assays in free light chain measurements in patients with renal impairment	11
Whole blood cytokine release assays reveal disparity between capillary blood sampling methods	11
Systemic evaluation of lymphocyte-bound C4d and immunoglobulins for diagnosis and activity monitoring of systemic lupus erythematosus	11
Serum human epididymis protein 4 is associated with disease severity in patients with IgA nephropathy	10
The liver-heart axis in patients with severe obesity: The association between liver fibrosis and chronic myocardial injury may be explained by shared risk factors of cardiovascular disease	10
The significance of PCSK-9′s level and polymorphism in premature coronary artery disease: Relation to risk and severity	10
Development of a second-tier method for C4, C5 and C2 acylcarnitine analysis in plasma	10
Elevated levels of β2-microglobulin in cerebrospinal fluid in adult patients with viral encephalitis/meningitis	10
Comment on the article titled “Serum cystatin C is associated with peripheral artery stiffness in patients with type 2 diabetes mellitus combined with chronic kidney disease”	10
Editorial Board	9
A review of temperature-related challenges and solutions for the Abbott i-STAT and Siemens Healthineers epoc devices	9
Low concentration of serum vitamin B12 may be a strong predictor of large-artery atherosclerosis stroke: A case-control study	9
POCT urine dipstick versus central laboratory analyses: Diagnostic performance and logistics in the medical emergency department	9
Identification of a novel 107 kb deletion in the alpha-globin gene cluster using third-generation sequencing	9
Multirule procedures vs moving average algorithms for IQC: An appropriate comparison reveals how best to combine their strengths	9
Alu cell-free DNA concentration, Alu index, and LINE-1 hypomethylation as a cancer predictor	9
Expression profile of long-noncoding RNAs MIR31HG, NKILA, and PACER in systemic lupus erythematosus patients	9
Thyroid panel reference intervals in healthy children and adolescents: A Spanish cohort	9
Prognostic value of circulating microRNAs compared to high-sensitivity troponin T in patients presenting with suspected acute coronary syndrome to the emergency department	9
Biomarkers in the prognostic evaluation of ischemic stroke: Is there benefit in the measurements of TREM-1 and TREM-2 in the acute phase?	9
Serum levels of 4-hydroxynonenal adducts and responding autoantibodies correlate with the pathogenesis from hyperglycemia to Alzheimer’s disease	8
High triglyceride-glucose index and HOMA-IR are associated with different cardiometabolic profile in adults from the ELSA-Brasil study	8
Serum extracellular vesicles with NSD1 and FBXO7 mRNA as novel biomarkers for gastric cancer	8
Complex biological patterns of soluble cytokines and CD163 in childhood necessitating age-specific reference intervals for evidence-based clinical interpretation	8
High serum levels of galectins 1 and 4 in osteoarthritis patients	8
Novel mutations associated with carnitine-acylcarnitine translocase and carnitine palmitoyl transferase 2 deficiencies in Malaysia	8
Identification of early derangements of coagulation, hematological and biochemical profiles in patients with acute pancreatitis	8
Serum levels of sonic hedgehog in patients with IgA nephropathy are closely associated with intrarenal arteriolar lesions	8

A circRNA-based ceRNA network shows its diagnostic value in non-small-cell lung cancer	8
IL-23 and IL-17 in acute ischemic stroke: Correlation with stroke scales and prognostic value	8
The use of aptamers in prostate cancer: A systematic review of theranostic applications	8
Determination of camostat and its metabolites in human plasma – Preservation of samples and quantification by a validated UHPLC-MS/MS method	8
Construction of a multi-classified decision tree model for identifying malignant pleural effusion and tuberculous pleural effusion	8
Novel microRNA biomarkers of systemic lupus erythematosus in plasma: miR-124-3p and miR-377-3p	8
Generation and characterization of a laforin nanobody inhibitor	8
Comparison of free plasma versus saliva mycophenolic acid exposure following mycophenolate mofetil administration in adult kidney transplant recipients	8
The impact of COVID-19 pandemic on technologic and process innovation in point-of-care diagnostics for sexually transmitted infections	8
Performance of saliva compared with nasopharyngeal swab for diagnosis of COVID-19 by NAAT in cross-sectional studies: Systematic review and meta-analysis	7
Evaluation of the role of serum DcR3 levels in the early clinical prognosis of patients with Crimean-Congo hemorrhagic fever	7
Characterizing M-protein light chain glycosylation via mass spectrometry	7
Krebs von den Lungen-6 (KL-6) as a diagnostic marker for pulmonary fibrosis: A systematic review and meta-analysis	7
Bias in IGF-1 concentrations and interpretation across three different clinical laboratory assays	7
Evaluation of commercial assays for the assessment of SARS-CoV-2 antibody response in hemodialysis patients	7
NUDT15: A bench to bedside success story	7
Machine learning to improve false-positive results in the Dutch newborn screening for congenital hypothyroidism	7
The development and validation of a high-capacity serological assay for celiac disease	7
Six novel variants in the PKLR gene associated with pyruvate kinase deficiency in Argentinian patients	7
A highly accurate mass spectrometry method for the quantification of phenylalanine and tyrosine on dried blood spots: Combination of liquid chromatography, phenylalanine/tyrosine-free blood calibrator	7
A simple method modification to increase separation of 2- and 3-hydroxyglutaric acid by GC–MS for clinical urine organic acids analysis	7
Characterizing the SARS-CoV-2 antibody response and associations with patient factors: Serological profiling of participants enrolled in the GENCOV study	7
The role of Monocyte Distribution Width (MDW) in the prognosis and monitoring of COVID-19 patients	7
Utility of fractional excretion of magnesium in diagnosing renal magnesium wasting in pediatric nephrology practice	7
The pitfalls and significance of using ratios and calculated parameters in laboratory medicine	7
Establishment and application of an immunoassay for the simultaneous detection of IgG and its subtype IgG4 autoantibodies against M-type phospholipase A2 receptor	7
Environmental factors in the preanalytical phase of laboratory testing	7
A new assay falsely increases lactate dehydrogenase in plasma but not in serum	6
Initial determination of COVID-19 seroprevalence among outpatients and healthcare workers in Minnesota using a novel SARS-CoV-2 total antibody ELISA	6
The changing landscape of autoantibody testing in myasthenia gravis in the setting of novel drug treatments	6
Establishing acceptable variation between instruments with dry chemistry methodology	6
Methods for analyzing positive cardiac troponin assay interference	6
Utility of the combination of high fluorescence cells and tumor markers for the diagnosis of malignant pleural effusions	6
Evaluation of an automated assay for eosinophil-derived neurotoxin in serum	6
Diagnostic performance and predictive value of D-dimer testing in patients referred to the emergency department for suspected myocardial infarction	6
Comparison of 8 methods for univariate statistical exclusion of pathological subpopulations for indirect reference intervals and biological variation studies	6
Orexin-A measurement in narcolepsy: A stability study and a comparison of LC-MS/MS and immunoassays	6
The use of freeze-dried blood samples affects the results of a dried blood spot analysis	6
Effects of vitamin B12 deficiency on risk and outcome of ischemic stroke	6
CXCL5 as a biomarker for early diagnosis and prognosis of sepsis: A comprehensive clinical evaluation	6
Cardiac troponin I is associated with ICU admission in pediatric patients with RSV	6
Association of phospholipid transfer protein (PLTP) and the effect of genetic variant rs5072 on hypertriglyceridemia and atherogenic dyslipidemia in children and adolescents from Southeastern Mexico	6
ROC of SII and FIB-4 index for predicting mortality in idiopathic pulmonary fibrosis patients	6
First and second trimester maternal serum markers for prenatal aneuploidy screening: An update on the adjustment factors for race, smoking, and insulin dependent diabetes mellitus	6
Relationship between serum Betatrophin, GPIHBP1, and LDL subfractions in patients with gestational diabetes mellitus	6
Clinical utility – Information about the usefulness of tests	6
Comparison of capillary and venous blood sampling for routine coagulation assays	6
Over-expression of KRT17 and MDK genes at mRNA levels in urine-exfoliated cells is associated with early non-invasive diagnosis of non-muscle-invasive bladder cancer	6
Quantitative abnormalities in the β-region of the electrophoretic profile of serum proteins as predictive markers of monoclonality: Machine learning for monoclonality prediction	6
The estimation of glomerular filtration in acute and critical illness: Challenges and opportunities	6
Effect of gravimetric correction and type of pipettes used in sample preparation on the precision of LC–MS/MS-based analyses	5
Clinical chemistry score misses fewer deaths as compared to troponin T alone in a United States emergency department population	5
Publisher’s note	5
Editorial Board	5
Editorial Board	5
Levels of lactic acid’s concordance with pH in pediatric parapneumonic pleural effusion	5
Non-linearity in lipase assays: A multicentric comparison on different analysers	5
Reducing AST orders by reviewing test panels	5
Evaluation of Siemens Atellica AMH assay and comparison with Roche, Beckman and Ansh Labs	5
Cerebrospinal fluid glucose is not altered in patients with dementia	5
Assessment of M-protein quantification using capillary electrophoresis and immunosubtraction-based integration in clinical samples with low M-protein concentrations	5
Canadian Society of Clinical Chemists (CSCC) consensus guidance for testing, selection and quality management of SARS-CoV-2 point-of-care tests	5
Evaluation of serum YKL-40 level among clinical risk scores for early mortality in acute pulmonary thromboembolism	5
Rapid detection of twenty-nine common Chinese glucose-6-phosphate dehydrogenase variants using a matrix-assisted laser desorption/ionization-time of flight mass spectrometry assay on dried blood spots	5
Association of ovarian response with picoAMH in women undergoing controlled ovarian hyperstimulation	5
Pharmacokinetics of baricitinib in critically ill COVID-19 patients	5
The prevalence of elevated biotin in patient cohorts presenting for routine endocrinology, sepsis, and infectious disease testing	5
Editorial Board	5
Low partial pressure of oxygen causes significant and unrecognized under-recovery of glucose on blood gas analyzers	5
Association of the C-terminal 42-peptide fragment of alpha-1 antitrypsin with the severity of ARDS: A pilot study	5
The potential of anti-glutamic acid decarboxylase antibodies to support a diagnosis of autoimmune diabetes mellitus	5
Accuracy-based proficiency testing for estradiol measurements	5
A verification and implementation plan for 50 blood gas analyzers across a large geographic area	5
Data mining: Biological and temporal factors associated with blood parathyroid hormone, vitamin D, and calcium concentrations in the Southwestern Chinese population	5
Editorial Board	5
Integrating quality control and external quality assurance	5
Whole-exome sequencing reveals a novel frameshift mutation in a consanguineous family with a hereditary coagulation factor XII deficiency	5
A novel metabolic disorder in the degradation pathway of endogenous methanol due to a mutation in the gene of alcohol dehydrogenase	5
Variation in processes and reporting of cerebrospinal fluid oligoclonal banding and associated tests and calculated indices across Canadian clinical laboratories	5
Clinical efficacy of thyroid-stimulating immunoglobulin detection for diagnosing Graves’ disease and predictors of responsiveness to methimazole	5

Editorial Board	5
Taking a step back from testing: Preanalytical considerations in molecular infectious disease diagnostics	5
Application and utility of boosting machine learning model based on laboratory test in the differential diagnosis of non-COVID-19 pneumonia and COVID-19	5
Do not report estimated average glucose (eAG) from HbA1c: Evidence is emerging	5
Editorial Board	5
Comparison of the 2021 and 2009 chronic kidney disease epidemiology collaboration creatinine equation for estimated glomerular filtration rate in a Chinese population	5
Editorial Board	5