Computers in Biology and Medicine

Article	Citations
Diffuse tumors: Molecular determinants shared by different cancer types	399
Editorial Board	352
Beyond accuracy: The need for explainable AI in biomedical voice technology	337
Discrepancy-based diffusion models for lesion detection in brain MRI	304
Identifying indications for novel drugs using electronic health records	301
Carotid single- and dual-layer stents reduce the wall adhesion of platelets by influencing flow and cellular transport	293
Pathogenicity classification of missense mutations based on deep generative model	291
A partially shared joint clustering framework for detecting protein complexes from multiple state-specific signed interaction networks	287
Contrastive learning based method for X-ray and CT registration under surgical equipment occlusion	278
Eye movement analysis for real-world settings using segmented linear regression	277
Advances in disease detection through retinal imaging: A systematic review	269
Longitudinal dementia trajectories for Alzheimer’s Disease characterization and prediction	265
Pharmacophore-guided computational modeling of quinolone-ATPase conjugate inhibitors targeting DNA GyrB subunit of Staphylococcus aureus	235
DRBpred: A sequence-based machine learning method to effectively predict DNA- and RNA-binding residues	233
Class-Specific Distribution Alignment for semi-supervised medical image classification	231
KNU-DTI: KNowledge United Drug-Target Interaction prediction	226
Fine-grained food image classification and recipe extraction using a customized deep neural network and NLP	217
Numerical analysis of coil designs to expedite fracture healing using dielectrophoresis with S method	214
Mass diffusion in multi-layer systems: an electrical analogue modelling approach	190
The role of the extracellular matrix in the reduction of lateral force transmission in muscle bundles: A finite element analysis	189
Discrete element method-based simulation system for predicting natural stone evacuation pathways in patients with urolithiasis	185
Data-driven discovery of sparse dynamical model of cardiovascular system for model predictive control	179
Counting on AR: EEG responses to incongruent information with real-world context	174
Development of closed-loop modelling framework for adaptive respiratory pacemakers	172
Predicting lung cancer survival based on clinical data using machine learning: A review	172

A deep learning model combining convolutional neural networks and a selective kernel mechanism for SSVEP-Based BCIs	168
Integrating biocomputational techniques for Breast cancer drug discovery via the HER-2, BCRA, VEGF and ER protein targets	159
A Three-branch Jointed Feature and Topology Decoder guided by game-theoretic interactions for temporomandibular joint segmentation	159
Multi-label classification of fundus images with graph convolutional network and LightGBM	156
Adaptive nonlinear filtering algorithms for removal of non-stationary noise in electronystagmographic signals	155
A mask R-CNN based automatic assessment system for nail psoriasis severity	151
Development and validation of a neutrophil extracellular traps-related gene signature for lower-grade gliomas	151
Enhancing and advancements in deep learning for melanoma detection: A comprehensive review	149
Structure, sensing and control of pneumatic upper limb rehabilitation system: Review and prospect	146
Efficient sleep apnea detection using single-lead ECG: A CNN-Transformer-LSTM approach	145
Causal relationship between slow waves of arterial, intracranial pressures and blood velocity in brain	143
Single-channel EEG based insomnia detection with domain adaptation	142
Artificial intelligence techniques for prediction of drug synergy in malignant diseases: Past, present, and future	141
Emotion recognition in EEG signals using deep learning methods: A review	140
Visual prior-based cross-modal alignment network for radiology report generation	140
A systematic review on the state-of-the-art strategies for protein representation	137
Insights from explainable AI in oesophageal cancer team decisions	135
The role of mechano-electric feedbacks and hemodynamic coupling in scar-related ventricular tachycardia	133
MCA-net: A multi-task channel attention network for Myocardial infarction detection and location using 12-lead ECGs	132
Multiscale differential geometry learning of networks with applications to single-cell RNA sequencing data	130
A deep learning based model using RNN-LSTM for the Detection of Schizophrenia from EEG data	127
Mapping synthetic binding proteins epitopes on diverse protein targets by protein structure prediction and protein-protein docking	127
Performance of multilabel machine learning models and risk stratification schemas for predicting stroke and bleeding risk in patients with non-valvular atrial fibrillation	127
Non-same-scale feature attention network based on BPD for medical image segmentation	124
GasHisSDB: A new gastric histopathology image dataset for computer aided diagnosis of gastric cancer	123
Effect of tumor heterogeneity on enhancing drug delivery to vascularized tumors using thermo-sensitive liposomes triggered by hyperthermia: A multi-scale and multi-physics computational model	123
Performance optimization of differential evolution with slime mould algorithm for multilevel breast cancer image segmentation	123
Analysis of domain shift in whole prostate gland, zonal and lesions segmentation and detection, using multicentric retrospective data	122
Modelling of thrombus formation, growth and embolisation in the left atrial appendage under atrial fibrillation	122
COVID-19 diagnosis using state-of-the-art CNN architecture features and Bayesian Optimization	121
D-glucose-conjugated thioureas containing 2-aminopyrimidine as potential multitarget inhibitors for type 2 diabetes mellitus: Synthesis and biological activity study	121
A transformer-based deep neural network for arrhythmia detection using continuous ECG signals	121
IVD fibrosis and disc collapse comprehensively aggravate vertebral body disuse osteoporosis and zygapophyseal joint osteoarthritis by posteriorly shifting the load transmission pattern	121
How CLSPN could demystify its prognostic value and potential molecular mechanism for hepatocellular carcinoma: A crosstalk study	120
Deep learning and machine learning approaches to classify stomach distant metastatic tumors using DNA methylation profiles	119
ILSHIP: An interpretable and predictive model for hypothyroidism	119
Insights into potential mechanisms of asthma patients with COVID-19: A study based on the gene expression profiling of bronchoalveolar lavage fluid	118
Automatic eczema classification in clinical images based on hybrid deep neural network	118
Stack-AAgP: Computational prediction and interpretation of anti-angiogenic peptides using a meta-learning framework	116
Identifying potent natural inhibitors of the hepatitis C virus NS3 protein using multiple computational and molecular approaches	115
Automated mitral valve segmentation in PLAX-view transthoracic echocardiography for anatomical assessment and risk stratification	114
Exploring the spike glycoprotein-encoding gene of SARS-CoV-2 using multifractal analysis: Unveiling structural complexity and implications for viral transmission	114
Automated mitral inflow Doppler peak velocity measurement using deep learning	113
KC-UNIT: Multi-kernel conversion using unpaired image-to-image translation with perceptual guidance in chest computed tomography imaging	112
Optimization of deep learning models for inference in low resource environments	112
KS-TMIL: A K-Stage Transformer approach with multiple instance learning model for ovarian cancer subtype classification	109
M3-Net++: A multi-scale, multi-level, multi-stream network for nuclei segmentation in breast cancer histopathology using hierarchical context extraction and hybrid loss optimization	109
Hybrid offline and self-knowledge distillation for acute ischemic stroke lesion segmentation from non-contrast CT scans	108
A general sample-weighted framework for epileptic seizure prediction	108
FCSU-Net: A novel full-scale Cross-dimension Self-attention U-Net with collaborative fusion of multi-scale feature for medical image segmentation	107

S2FLNet: Hepatic steatosis detection network with body shape	106
Uniqueness of inspiratory airflow patterns in a realistic rat nasal cavity	106
Context-aggregator: An approach of loss- and class imbalance-aware aggregation in federated learning	103
Automated identification of patient subgroups: A case-study on mortality of COVID-19 patients admitted to the ICU	103
Vectorial-based analysis of dual-tracer PET imaging: A proof of concept	101
A self-supervised COVID-19 CT recognition system with multiple regularizations	101
Computational prediction of protein folding rate using structural parameters and network centrality measures	101
AGNet: Automatic generation network for skin imaging reports	100
Dynamic topography analysis of the cornea and its application to the diagnosis of keratoconus	99
A novel mobile phone and tablet application for automatized calculation of pain extent	99
Identification of JUN as determinant of osteoarthritis and its inhibition by the Chinese herbal formulae Zhuanggu Huoxue Tang	98
A computational model of the effects of macronutrients absorption and physical exercise on hormonal regulation and metabolic homeostasis	98
Editorial Board	97
Dual-Stream Subspace Clustering Network for revealing gene targets in Alzheimer's disease	96
Identification of anti-cancer organometallic compounds by inhibition of BCL-2/Bax interactions	96
CARES: A Corpus for classification of Spanish Radiological reports	96
Functional identification and prediction of lncRNAs in esophageal cancer	95
Electroanatomical mapping of the stomach with simultaneous biomagnetic measurements	92
Deep-learning-based real-time individualization for reduce-order haemodynamic model	89
Synergistic eigenanalysis of covariance and Hessian matrices for enhanced binary classification on health datasets	89
Evaluation of the mechanical behaviour of the expandable wedge locked nail fixation in retrograde use: A finite element study	88
Artificial vascular image generation using blood vessel texture maps	87
Detecting IDH and TERTp mutations in diffuse gliomas using 1H-MRS with attention deep-shallow networks	86
DeepSMR: Decoding high-complex motor imagery via subject-dependent multi-feature refinement in deep convolutional networks	86
Drug repositioning for rosacea disease: Biological TARGET identification, molecular docking, pharmacophore mapping, and molecular dynamics analysis	86
Deep learning-based feature discovery for decoding phenotypic plasticity in pediatric high-grade gliomas single-cell transcriptomics	86
Extinction and stationary distribution of a stochastic COVID-19 epidemic model with time-delay	85
Two-stage error detection to improve electron microscopy image mosaicking	85
Towards a better understanding of TF-DNA binding prediction from genomic features	85
A comprehensive analysis of single-cell RNA transcriptome reveals unique SPP1+ chondrocytes in human osteoarthritis	85
CauDR: A causality-inspired domain generalization framework for fundus-based diabetic retinopathy grading	85
Pedicle drilling force control of a robotic surgical system via spine-soft tissue coupling model and parameters optimization	85
A method for predicting linear and conformational B-cell epitopes in an antigen from its primary sequence	85
JoCoRank: Joint correlation learning with ranking similarity regularization for imbalanced fetal brain age regression	84
Corrigendum to “Unraveling the molecular landscape of non-small cell lung cancer: Integrating bioinformatics and statistical approaches to identify biomarkers and drug repurposing” [Comput. Biol. Med.	84
Prediction of colorectal cancer based on taxonomic levels of microorganisms and discovery of taxonomic biomarkers using the Grouping-Scoring-Modeling (G-S-M) approach	84
Editorial Board	84
SSMT-PANBERT: A single-stage multitask model for phenotype extraction and assertion negation detection in unstructured clinical text	83
Enhancing cell instance segmentation in scanning electron microscopy images via a deep contour closing operator	83
LSDVvac: An immunoinformatics database for vaccine design against lumpy skin disease virus	83
Disclosing neonatal pain in real-time: AI-derived pain sign from continuous assessment of facial expressions	83
You get the best of both worlds? Integrating deep learning and traditional machine learning for breast cancer risk prediction	83
Deriving a suitable schedule through robust H	82
AIScholar: An OpenFaaS-enhanced cloud platform for intelligent medical data analytics	82
Automatic segmentation of intraluminal thrombosis of abdominal aortic aneurysms from CT angiography using a mixed-scale-driven multiview perception network (M2Net) model	82
Wearable-based human flow experience recognition enhanced by transfer learning methods using emotion data	81
MulStack: An ensemble learning prediction model of multilabel mRNA subcellular localization	81
In silico evaluation of lattice designs for additively manufactured total hip implants	79
SURVS: A Swin-Unet and game theory-based unsupervised segmentation method for retinal vessel	79
A novel Harris Hawks Optimization-based clustering method for elucidating genetic associations in osteoarthritis and Diverse Cancer Types	79
Dynamic Statistical Attention-based lightweight model for Retinal Vessel Segmentation: DyStA-RetNet	78
Temporal relative transformer encoding cooperating with channel attention for EEG emotion analysis	78
An efficient image segmentation method for skin cancer imaging using improved golden jackal optimization algorithm	78
DrugormerDTI: Drug Graphormer for drug–target interaction prediction	77
Enhanced depression detection from speech using Quantum Whale Optimization Algorithm for feature selection	77
Predictive modeling for early detection of biliary atresia in infants with cholestasis: Insights from a machine learning study	77
Semi-empirical Anticoagulation Model (SAM): Dose prediction during warfarin therapy	76
A robust drug recall supply chain management system using hyperledger blockchain ecosystem	76
Prediction of protein N-terminal acetylation modification sites based on CNN-BiLSTM-attention model	76
Hemodynamic alternations following stent deployment and post-dilation in a heavily calcified coronary artery: In silico and ex-vivo approaches	76
Integrating CNN and Bi-LSTM for protein succinylation sites prediction based on Natural Language Processing technique	76
ST-SRPerf: Continuous spatiotemporal representation for perfusion MRI super-resolution through neural ODE and implicit neural representation	75
Anemia prediction using gene expression programming (GEP) and explainable artificial intelligence approaches	75
HOTGpred: Enhancing human O-linked threonine glycosylation prediction using integrated pretrained protein language model-based features and multi-stage feature selection approach	75
Identifying fetal status with fetal heart rate: Deep learning approach based on long convolution	75
Artificial intelligence for identification of candidates for device-aided therapy in Parkinson's disease: DELIST-PD study	75
Context encoder transfer learning approaches for retinal image analysis	74
Conditional GAN based augmentation for predictive modeling of respiratory signals	74
Classical Simulations on Quantum Computers: Interface-Driven Peptide Folding on Simulated Membrane Surfaces	74
Quantifying the influence of combined lung and kidney support using a cardiovascular model and sensitivity analysis-informed parameter identification	74
Triage and monitoring of COVID-19 patients in intensive care using unsupervised machine learning	74
Computer models evaluating hand tremors in Parkinson's disease patients	73
Quantitative computed tomography imaging-based classification of cement dust-exposed subjects with an artificial neural network technique	73
Reversing skin cancer adversarial examples by multiscale diffusive and denoising aggregation mechanism	73
Improved predictive diagnosis of diabetic macular edema based on hybrid models: An observational study	73
Simulated annealing aided genetic algorithm for gene selection from microarray data	72
Gene-related Parkinson's disease diagnosis via feature-based multi-branch octave convolution network	72
A computational study of venom as drug library: Discovery of multifunctional astacin-like metalloproteases from Androctonus zagrosensis venom gland transcriptome	72
Revised NMS-driven pipeline for heart valve regurgitation and Kawasaki disease coronary aneurysm localization	71
Prediction of lung cancer metastasis by gene expression	71

Eudesma-4(15), 7-dien-1-β-ol, A promising natural drug candidate for Alzheimer's disease targeting the NMDA pathway: GC-MS identification, molecular docking, pharmacokinetic and molecular dynamic anal	71
Thyroid region prior guided attention for ultrasound segmentation of thyroid nodules	71
Hierarchical cumulative network for unsupervised medical image registration	71
AELGNet: Attention-based Enhanced Local and Global Features Network for medicinal leaf and plant classification	70
Dynamical pattern of successive bits to predict the outcomes of the SSRI and rTMS depression therapies using EEG signals	70
Enhancing targeted tumor treatment: A novel fuzzy logic framework for precision drug delivery strategy selection	70
Predicting diameter and tensile strength of electrospun fibers for biomedicine: A comparison of Box-Behnken design, traditional machine learning and deep learning	69
Red blood cell passage through deformable interendothelial slits in the spleen: Insights into splenic filtration and hemodynamics	69
The role and potential of computer-aided drug discovery strategies in the discovery of novel antimicrobials	69
Unraveling the complexities of pathological voice through saliency analysis	69
Graph neural network-based subgraph analysis for predicting adverse drug events	68
Sparse Dynamic Volume TransUNet with multi-level edge fusion for brain tumor segmentation	68
Assessing clinical utility of machine learning and artificial intelligence approaches to analyze speech recordings in multiple sclerosis: A pilot study	67
A review of deep learning-based information fusion techniques for multimodal medical image classification	67
Identification of potential agonist-like molecules for α2-adrenergic receptor by multi-layer virtual screening to combat sinusitis	67
An improved RIME optimization algorithm for lung cancer image segmentation	67
Molecular modelling and experimental validation identified a new therapeutic inhibitor of toxoplasmosis	67
Identification of lncRNA associated with the SERPINE1 gene in colorectal cancer through TGF-β pathway	66
Prostate158 - An expert-annotated 3T MRI dataset and algorithm for prostate cancer detection	66
Structure-based design of promising natural products to inhibit thymidylate kinase from Monkeypox virus and validation using free energy calculations	66
Multi-constraint point set registration with redundant point removal for the registration of coronary arteries	66
Automated tool detection with deep learning for monitoring kinematics and eye-hand coordination in microsurgery	65
An efficient model for extracting respiratory and blood oxygen saturation data from photoplethysmogram signals by removing motion artifacts using heuristic-aided ensemble learning model	65
EpiTEAmDNA: Sequence feature representation via transfer learning and ensemble learning for identifying multiple DNA epigenetic modification types across species	65
REDDA: Integrating multiple biological relations to heterogeneous graph neural network for drug-disease association prediction	65
A novel hybrid ViT-LSTM model with explainable AI for brain stroke detection and classification in CT images: A case study of Rajshahi region	64
DE-JANet: A unified network based on dual encoder and joint attention for Alzheimer’s disease classification using multi-modal data	64
Exploring molecular mechanisms of diazinon toxicity in HT22 hippocampal neurons through integrated miRNA and mRNA profiling	64
Enclosing 95% confidence area and volume to center of pressure and center of mass in posturography using optimization algorithm and coordinate ascent methods	63
Editorial Board	63
A novel mTOR-associated gene signature for predicting prognosis and evaluating tumor immune microenvironment in lung adenocarcinoma	63
A novel virtual robotic platform for controlling six degrees of freedom assistive devices with body-machine interfaces	63
Molecular hybridization assisted multi-technique approach for designing USP21 inhibitors to halt catalytic triad-mediated nucleophilic attack and suppress pancreatic ductal adenocarcinoma progression:	63
Estimation of potassium levels in hemodialysis patients by T wave nonlinear dynamics and morphology markers	62
Characterization of cancer subtypes associated with clinical outcomes by multi-omics integrative clustering	62
Cross attention guided multi-scale feature fusion for false-positive reduction in pulmonary nodule detection	62
Identification of telomere-associated gene signatures to predict prognosis and drug sensitivity in glioma	62
A sleep staging model on wavelet-based adaptive spectrogram reconstruction and light weight CNN	61
Genetic algorithm based image reconstruction applying the digital holography process with the Discrete Orthonormal Stockwell Transform technique for diagnosis of COVID-19	61
Biochemical reaction network topology defines dose-dependent Drug–Drug interactions	61
Guardian-BERT: Early detection of self-injury and suicidal signs with language technologies in electronic health reports	60
A regularization method to improve adversarial robustness of neural networks for ECG signal classification	60
SNN6mA: Improved DNA N6-methyladenine site prediction using Siamese network-based feature embedding	60
Joint cardiac tissue conductivity and activation time estimation using confirmatory factor analysis	60
Respiratory modulation of the heart rate: A potential biomarker of cardiorespiratory function in human	60
Breast cancer detection and classification: A study on the specification and implementation of multilayer perceptron analog artificial neural networks	60
Cancer-inspired genomics mapper model for the generation of synthetic DNA sequences with desired genomics signatures	60
SEPO-FI: Deep-learning based software to calculate fusion index of muscle cells	59
Direct parametric reconstruction in dynamic PET using deep image prior and a novel parameter magnification strategy	59
Individual thigh muscle and proximal femoral features predict displacement in femoral neck Fractures: An AI-driven CT analysis	59
Prediction of drug-target interactions via neural tangent kernel extraction feature matrix factorization model	59
Predicted and Explained: Transforming drug discovery with AI for high-precision receptor-ligand interaction modeling and binding analysis	59
Bone marrow sparing oriented multi-model image registration in cervical cancer radiotherapy	59
Precision oncology informatics for anticancer drug combination responses: A systematic review	58
QMaxViT-Unet+: A query-based MaxViT-Unet with edge enhancement for scribble-supervised segmentation of medical images	58
Editorial Board	58
Classifying alkaliphilic proteins using embeddings from protein language model	58
Editorial Board	58
Application of Explainable Artificial Intelligence for personalized childhood weight management using IoT data	58
MicroRNA regulation of PPARG Signalling: Therapeutic implications for pulmonary hypertension	58
Spatiotemporal modeling of host–pathogen interactions using level-set method	57
Systematic comparison of genome information processing and boundary recognition tools used for genomic island detection	57
Repeated measures analysis for steady-state evoked potentials	57
Lightweight triangular mesh deformable reconstruction for low quality 3D organ models: Thickness noise and uneven topology	57
An adaptive language model-based intelligent medication assistant for the decision support of antidepressant prescriptions	57
Enhancing nuclei segmentation in breast histopathology images using U-Net with backbone architectures	57
Automated engineered-stone silicosis screening and staging using Deep Learning with X-rays	57
Enhancing search strategies for systematic reviews on drug Harms: An evaluation of the utility of ChatGPT in error detection and keyword generation	56
Enhanced single-cell RNA-seq embedding through gene expression and data-driven gene-gene interaction integration	56
Design and hierarchical analysis of magnetic actuated robot: A governing equation based approach	56
Ce	56
Validation of fluid-structure interaction simulations of the opening phase of phantom mitral heart valves under physiologically inspired conditions	56
CFD simulations of inhalation through a subject-specific human larynx – Impact of the unilateral vocal fold immobility	56
Two-stage data augmentation for improved ASR performance for dysarthric speech	56
DNA protein binding recognition based on lifelong learning	56
FIM: A fatigued-injured muscle model based on the sliding filament theory	56
PNMC: Four-dimensional conebeam CT reconstruction combining prior network and motion compensation	56
Three-dimensional morphology scoring of hepatocellular carcinoma stratifies prognosis and immune infiltration	56
Medical application of deep-learning-based head pose estimation from RGB image sequence	56
Characterizing patients at higher cardiovascular risk for prescribed stimulants: Learning from health records data with predictive analytics and data mining techniques	56
Interplay of mutations, alternate mechanisms, and treatment breaks in leukaemia: Understanding and implications studied with stochastic models	56
Deep learning image registration for cardiac motion estimation in adult and fetal echocardiography via a focus on anatomic plausibility and texture quality of warped image	56
Evaluation of Cellpose segmentation with sequential thresholding for instance segmentation of cytoplasms within autofluorescence images	55
Metagenome comparison (MC): A new framework for detecting unique/enriched OMUs (operational metagenomic units) derived from whole-genome sequencing reads	55
A multimodal deep learning framework for enzyme turnover prediction with missing modality	55
Designing a bioadjuvant candidate vaccine targeting infectious bursal disease virus (IBDV) using viral VP2 fusion and chicken IL-2 antigenic epitope: A bioinformatics approach	55
Wearable multisource quantitative gait analysis of Parkinson's diseases	55
A mathematical model of tissue axial and radial diffusion in the microvasculature for intravascular microscopy and phosphorescence quenching data	55
A computational optimization study of a self-expandable transcatheter aortic valve	54
PIPE-Net: A pyramidal-input-parallel-encoding network for the segmentation of corneal layer interfaces in OCT images	54
Building digital twins for personalized cardiovascular medicine: Advances, challenges, and future directions	54
Novel classification of brain vascular tortuosity measures: A systematic review	54
NIMEQ-SACNet: A novel self-attention precision medicine model for vision-threatening diabetic retinopathy using image data	54
Computationally efficient model to predict the deformations of a cellular foot orthotic	54
Disruption of histidine biosynthesis in Acinetobacter baumannii by Tubuloside B from Cistanche tubulosa	53