Computers in Biology and Medicine

Article	Citations
Editorial Board	456
Editorial Board	405
Diffuse tumors: Molecular determinants shared by different cancer types	357
Identifying indications for novel drugs using electronic health records	308
Hybrid offline and self-knowledge distillation for acute ischemic stroke lesion segmentation from non-contrast CT scans	300
Carotid single- and dual-layer stents reduce the wall adhesion of platelets by influencing flow and cellular transport	283
Identification of JUN as determinant of osteoarthritis and its inhibition by the Chinese herbal formulae Zhuanggu Huoxue Tang	277
Pathogenicity classification of missense mutations based on deep generative model	271
Pedicle drilling force control of a robotic surgical system via spine-soft tissue coupling model and parameters optimization	262
A partially shared joint clustering framework for detecting protein complexes from multiple state-specific signed interaction networks	251
S2FLNet: Hepatic steatosis detection network with body shape	245
Automated identification of patient subgroups: A case-study on mortality of COVID-19 patients admitted to the ICU	237
Contrastive learning based method for X-ray and CT registration under surgical equipment occlusion	231
Enhancing targeted tumor treatment: A novel fuzzy logic framework for precision drug delivery strategy selection	218
A self-supervised COVID-19 CT recognition system with multiple regularizations	216
Multiscale differential geometry learning of networks with applications to single-cell RNA sequencing data	210
Causal relationship between slow waves of arterial, intracranial pressures and blood velocity in brain	208
Development and validation of a neutrophil extracellular traps-related gene signature for lower-grade gliomas	207
Towards a better understanding of TF-DNA binding prediction from genomic features	206
Longitudinal dementia trajectories for Alzheimer’s Disease characterization and prediction	203
Deriving a suitable schedule through robust H	201
Advances in disease detection through retinal imaging: A systematic review	201
Eye movement analysis for real-world settings using segmented linear regression	200
A novel Harris Hawks Optimization-based clustering method for elucidating genetic associations in osteoarthritis and Diverse Cancer Types	192
Analysis of COVID-19 pandemic in USA, using Topological Weighted Centroid	182

Adaptive nonlinear filtering algorithms for removal of non-stationary noise in electronystagmographic signals	181
Graph neural network-based subgraph analysis for predicting adverse drug events	177
Unraveling the complexities of pathological voice through saliency analysis	170
Class-Specific Distribution Alignment for semi-supervised medical image classification	167
Discrete element method-based simulation system for predicting natural stone evacuation pathways in patients with urolithiasis	160
Artificial intelligence techniques for prediction of drug synergy in malignant diseases: Past, present, and future	157
A novel mobile phone and tablet application for automatized calculation of pain extent	157
Evaluation of the mechanical behaviour of the expandable wedge locked nail fixation in retrograde use: A finite element study	157
IVD fibrosis and disc collapse comprehensively aggravate vertebral body disuse osteoporosis and zygapophyseal joint osteoarthritis by posteriorly shifting the load transmission pattern	153
Enhancing cell instance segmentation in scanning electron microscopy images via a deep contour closing operator	153
Prediction of protein N-terminal acetylation modification sites based on CNN-BiLSTM-attention model	148
Conditional GAN based augmentation for predictive modeling of respiratory signals	145
Enhancing and advancements in deep learning for melanoma detection: A comprehensive review	145
The role of the extracellular matrix in the reduction of lateral force transmission in muscle bundles: A finite element analysis	145
Temporal relative transformer encoding cooperating with channel attention for EEG emotion analysis	143
Analysis of domain shift in whole prostate gland, zonal and lesions segmentation and detection, using multicentric retrospective data	141
Assessing clinical utility of machine learning and artificial intelligence approaches to analyze speech recordings in multiple sclerosis: A pilot study	140
Disclosing neonatal pain in real-time: AI-derived pain sign from continuous assessment of facial expressions	140
ILSHIP: An interpretable and predictive model for hypothyroidism	139
An efficient image segmentation method for skin cancer imaging using improved golden jackal optimization algorithm	139
Drug repurposing of triazoles against mucormycosis using molecular docking: A short communication	139
Non-same-scale feature attention network based on BPD for medical image segmentation	139
A systematic review on the state-of-the-art strategies for protein representation	138
A comprehensive analysis of single-cell RNA transcriptome reveals unique SPP1+ chondrocytes in human osteoarthritis	136
Fine-grained food image classification and recipe extraction using a customized deep neural network and NLP	136
A mask R-CNN based automatic assessment system for nail psoriasis severity	136
Integrating CNN and Bi-LSTM for protein succinylation sites prediction based on Natural Language Processing technique	135
Novel ensemble of optimized CNN and dynamic selection techniques for accurate Covid-19 screening using chest CT images	133
Numerical analysis of coil designs to expedite fracture healing using dielectrophoresis with S method	131
Beyond accuracy: The need for explainable AI in biomedical voice technology	130
Personalized brachytherapy dose reconstruction using deep learning	129
Automatic segmentation of intraluminal thrombosis of abdominal aortic aneurysms from CT angiography using a mixed-scale-driven multiview perception network (M2Net) model	126
Effect of tumor heterogeneity on enhancing drug delivery to vascularized tumors using thermo-sensitive liposomes triggered by hyperthermia: A multi-scale and multi-physics computational model	124
SURVS: A Swin-Unet and game theory-based unsupervised segmentation method for retinal vessel	123
AELGNet: Attention-based Enhanced Local and Global Features Network for medicinal leaf and plant classification	120
Discrepancy-based diffusion models for lesion detection in brain MRI	118
Automatic eczema classification in clinical images based on hybrid deep neural network	117
Functional identification and prediction of lncRNAs in esophageal cancer	116
Prediction of lung cancer metastasis by gene expression	116
COVID-19 diagnosis using state-of-the-art CNN architecture features and Bayesian Optimization	115
Mapping synthetic binding proteins epitopes on diverse protein targets by protein structure prediction and protein-protein docking	114
Performance optimization of differential evolution with slime mould algorithm for multilevel breast cancer image segmentation	113
Visual prior-based cross-modal alignment network for radiology report generation	112
Context encoder transfer learning approaches for retinal image analysis	112
CauDR: A causality-inspired domain generalization framework for fundus-based diabetic retinopathy grading	111
Two-stage error detection to improve electron microscopy image mosaicking	110
JoCoRank: Joint correlation learning with ranking similarity regularization for imbalanced fetal brain age regression	110
Corrigendum to “Unraveling the molecular landscape of non-small cell lung cancer: Integrating bioinformatics and statistical approaches to identify biomarkers and drug repurposing” [Comput. Biol. Med.	109
Editorial Board	109
Modelling of thrombus formation, growth and embolisation in the left atrial appendage under atrial fibrillation	108

Predictive modeling for early detection of biliary atresia in infants with cholestasis: Insights from a machine learning study	108
Drug repositioning for rosacea disease: Biological TARGET identification, molecular docking, pharmacophore mapping, and molecular dynamics analysis	107
Mass diffusion in multi-layer systems: an electrical analogue modelling approach	107
Vectorial-based analysis of dual-tracer PET imaging: A proof of concept	104
Electroanatomical mapping of the stomach with simultaneous biomagnetic measurements	104
Prediction of colorectal cancer based on taxonomic levels of microorganisms and discovery of taxonomic biomarkers using the Grouping-Scoring-Modeling (G-S-M) approach	104
Identification of anti-cancer organometallic compounds by inhibition of BCL-2/Bax interactions	104
Automated mitral inflow Doppler peak velocity measurement using deep learning	104
Dynamic topography analysis of the cornea and its application to the diagnosis of keratoconus	104
Multi-constraint point set registration with redundant point removal for the registration of coronary arteries	104
Deep-learning-based real-time individualization for reduce-order haemodynamic model	104
Dual-Stream Subspace Clustering Network for revealing gene targets in Alzheimer's disease	103
Development of closed-loop modelling framework for adaptive respiratory pacemakers	102
Insights from explainable AI in oesophageal cancer team decisions	101
A Three-branch Jointed Feature and Topology Decoder guided by game-theoretic interactions for temporomandibular joint segmentation	101
LSDVvac: An immunoinformatics database for vaccine design against lumpy skin disease virus	98
Gene-related Parkinson's disease diagnosis via feature-based multi-branch octave convolution network	98
Semi-empirical Anticoagulation Model (SAM): Dose prediction during warfarin therapy	98
FCSU-Net: A novel full-scale Cross-dimension Self-attention U-Net with collaborative fusion of multi-scale feature for medical image segmentation	98
Improved predictive diagnosis of diabetic macular edema based on hybrid models: An observational study	97
In silico evaluation of lattice designs for additively manufactured total hip implants	97
Counting on AR: EEG responses to incongruent information with real-world context	97
A general sample-weighted framework for epileptic seizure prediction	97
Identification of potential agonist-like molecules for α2-adrenergic receptor by multi-layer virtual screening to combat sinusitis	97
Classical Simulations on Quantum Computers: Interface-Driven Peptide Folding on Simulated Membrane Surfaces	96
Uniqueness of inspiratory airflow patterns in a realistic rat nasal cavity	96
MulStack: An ensemble learning prediction model of multilabel mRNA subcellular localization	95
Data-driven discovery of sparse dynamical model of cardiovascular system for model predictive control	95
DRBpred: A sequence-based machine learning method to effectively predict DNA- and RNA-binding residues	94
An efficient model for extracting respiratory and blood oxygen saturation data from photoplethysmogram signals by removing motion artifacts using heuristic-aided ensemble learning model	94
Extinction and stationary distribution of a stochastic COVID-19 epidemic model with time-delay	94
Quantifying the influence of combined lung and kidney support using a cardiovascular model and sensitivity analysis-informed parameter identification	92
AIScholar: An OpenFaaS-enhanced cloud platform for intelligent medical data analytics	91
Simulated annealing aided genetic algorithm for gene selection from microarray data	90
Detecting IDH and TERTp mutations in diffuse gliomas using 1H-MRS with attention deep-shallow networks	90
Hierarchical cumulative network for unsupervised medical image registration	89
Computer models evaluating hand tremors in Parkinson's disease patients	89
Artificial vascular image generation using blood vessel texture maps	88
GasHisSDB: A new gastric histopathology image dataset for computer aided diagnosis of gastric cancer	88
Identification of lncRNA associated with the SERPINE1 gene in colorectal cancer through TGF-β pathway	88
Integrating biocomputational techniques for Breast cancer drug discovery via the HER-2, BCRA, VEGF and ER protein targets	87
EpiTEAmDNA: Sequence feature representation via transfer learning and ensemble learning for identifying multiple DNA epigenetic modification types across species	86
Hemodynamic alternations following stent deployment and post-dilation in a heavily calcified coronary artery: In silico and ex-vivo approaches	86
Stack-AAgP: Computational prediction and interpretation of anti-angiogenic peptides using a meta-learning framework	85
Potential inhibitors of the main protease of SARS-CoV-2 and modulators of arachidonic acid pathway: Non-steroidal anti-inflammatory drugs against COVID-19	85
Triage and monitoring of COVID-19 patients in intensive care using unsupervised machine learning	85
Pharmacophore-guided computational modeling of quinolone-ATPase conjugate inhibitors targeting DNA GyrB subunit of Staphylococcus aureus	84
AGNet: Automatic generation network for skin imaging reports	84
KNU-DTI: KNowledge United Drug-Target Interaction prediction	84
The role of mechano-electric feedbacks and hemodynamic coupling in scar-related ventricular tachycardia	84
Dynamic Statistical Attention-based lightweight model for Retinal Vessel Segmentation: DyStA-RetNet	83
CARES: A Corpus for classification of Spanish Radiological reports	83
Artificial intelligence for identification of candidates for device-aided therapy in Parkinson's disease: DELIST-PD study	83
Performance of multilabel machine learning models and risk stratification schemas for predicting stroke and bleeding risk in patients with non-valvular atrial fibrillation	83
Multi-label classification of fundus images with graph convolutional network and LightGBM	82
A deep learning based model using RNN-LSTM for the Detection of Schizophrenia from EEG data	82
Context-aggregator: An approach of loss- and class imbalance-aware aggregation in federated learning	82
A computational model of the effects of macronutrients absorption and physical exercise on hormonal regulation and metabolic homeostasis	81
You get the best of both worlds? Integrating deep learning and traditional machine learning for breast cancer risk prediction	81
A review of deep learning-based information fusion techniques for multimodal medical image classification	81
Emotion recognition in EEG signals using deep learning methods: A review	81
HOTGpred: Enhancing human O-linked threonine glycosylation prediction using integrated pretrained protein language model-based features and multi-stage feature selection approach	81
Quantitative computed tomography imaging-based classification of cement dust-exposed subjects with an artificial neural network technique	80
Single-channel EEG based insomnia detection with domain adaptation	79
An improved RIME optimization algorithm for lung cancer image segmentation	78
Prostate158 - An expert-annotated 3T MRI dataset and algorithm for prostate cancer detection	78
Automated tool detection with deep learning for monitoring kinematics and eye-hand coordination in microsurgery	78
Wearable-based human flow experience recognition enhanced by transfer learning methods using emotion data	78
MCA-net: A multi-task channel attention network for Myocardial infarction detection and location using 12-lead ECGs	78
A robust drug recall supply chain management system using hyperledger blockchain ecosystem	78
REDDA: Integrating multiple biological relations to heterogeneous graph neural network for drug-disease association prediction	77
Sparse Dynamic Volume TransUNet with multi-level edge fusion for brain tumor segmentation	77
Identifying fetal status with fetal heart rate: Deep learning approach based on long convolution	77
How CLSPN could demystify its prognostic value and potential molecular mechanism for hepatocellular carcinoma: A crosstalk study	76
Reversing skin cancer adversarial examples by multiscale diffusive and denoising aggregation mechanism	76
Structure-based design of promising natural products to inhibit thymidylate kinase from Monkeypox virus and validation using free energy calculations	76
A hybrid methodology for breast screening and cancer diagnosis using thermography	76
Molecular modelling and experimental validation identified a new therapeutic inhibitor of toxoplasmosis	76
Deep learning and machine learning approaches to classify stomach distant metastatic tumors using DNA methylation profiles	75
DE-JANet: A unified network based on dual encoder and joint attention for Alzheimer’s disease classification using multi-modal data	75

A method for predicting linear and conformational B-cell epitopes in an antigen from its primary sequence	75
Predicting lung cancer survival based on clinical data using machine learning: A review	75
The role and potential of computer-aided drug discovery strategies in the discovery of novel antimicrobials	74
Insights into potential mechanisms of asthma patients with COVID-19: A study based on the gene expression profiling of bronchoalveolar lavage fluid	74
Thyroid region prior guided attention for ultrasound segmentation of thyroid nodules	73
DrugormerDTI: Drug Graphormer for drug–target interaction prediction	73
Red blood cell passage through deformable interendothelial slits in the spleen: Insights into splenic filtration and hemodynamics	73
A transformer-based deep neural network for arrhythmia detection using continuous ECG signals	73
Computational prediction of protein folding rate using structural parameters and network centrality measures	73
Identification of molecular and cellular infection response biomarkers associated with anthrax infection through comparative analysis of gene expression data	71
A novel hybrid ViT-LSTM model with explainable AI for brain stroke detection and classification in CT images: A case study of Rajshahi region	71
Exploring molecular mechanisms of diazinon toxicity in HT22 hippocampal neurons through integrated miRNA and mRNA profiling	71
D-glucose-conjugated thioureas containing 2-aminopyrimidine as potential multitarget inhibitors for type 2 diabetes mellitus: Synthesis and biological activity study	71
Enhanced depression detection from speech using Quantum Whale Optimization Algorithm for feature selection	71
Transcriptome analysis displays new molecular insights into the mechanisms of action of Mebendazole in gastric cancer cells	71
Synergistic eigenanalysis of covariance and Hessian matrices for enhanced binary classification on health datasets	71
Molecular hybridization assisted multi-technique approach for designing USP21 inhibitors to halt catalytic triad-mediated nucleophilic attack and suppress pancreatic ductal adenocarcinoma progression:	71
Smoke veil prior regularized surgical field desmoking without paired in-vivo data	70
A computational framework to simulate the thermochemical process during thermochemical ablation of biological tissues	70
Impact of physiological loads of arterial wall on nucleus deformation in endothelial cells: A computational study	70
Effective fall detection and post-fall breath rate tracking using a low-cost CW Doppler radar sensor	70
Validation of fluid-structure interaction simulations of the opening phase of phantom mitral heart valves under physiologically inspired conditions	69
FIM: A fatigued-injured muscle model based on the sliding filament theory	69
Interplay of mutations, alternate mechanisms, and treatment breaks in leukaemia: Understanding and implications studied with stochastic models	69
PNMC: Four-dimensional conebeam CT reconstruction combining prior network and motion compensation	69
Identification of a novel gene signature for the prognosis of sepsis	68
Ce	68
Characterizing patients at higher cardiovascular risk for prescribed stimulants: Learning from health records data with predictive analytics and data mining techniques	68
Privacy preserving distributed learning classifiers – Sequential learning with small sets of data	68
Atten-Nonlocal Unet: Attention and Non-local Unet for medical image segmentation	68
Automated engineered-stone silicosis screening and staging using Deep Learning with X-rays	67
A computational optimization study of a self-expandable transcatheter aortic valve	67
Repeated measures analysis for steady-state evoked potentials	67
Deep learning image registration for cardiac motion estimation in adult and fetal echocardiography via a focus on anatomic plausibility and texture quality of warped image	67
A fully-convolutional residual encoder-decoder neural network to localize breast cancer on histopathology images	66
Biochemical reaction network topology defines dose-dependent Drug–Drug interactions	66
Genetic algorithm based image reconstruction applying the digital holography process with the Discrete Orthonormal Stockwell Transform technique for diagnosis of COVID-19	66
Cross attention guided multi-scale feature fusion for false-positive reduction in pulmonary nodule detection	66
Estimation of potassium levels in hemodialysis patients by T wave nonlinear dynamics and morphology markers	65
Collaborative networks of transformers and convolutional neural networks are powerful and versatile learners for accurate 3D medical image segmentation	65
Computationally efficient model to predict the deformations of a cellular foot orthotic	65
Role of [18F]-PSMA-1007 PET radiomics for seminal vesicle invasion prediction in primary prostate cancer	65
CFD simulations of inhalation through a subject-specific human larynx – Impact of the unilateral vocal fold immobility	65
Three-dimensional morphology scoring of hepatocellular carcinoma stratifies prognosis and immune infiltration	65
Automatic segmentation and classification of Papanicolaou-stained cells and dataset for oral cancer detection	64
Joint cardiac tissue conductivity and activation time estimation using confirmatory factor analysis	64
Pathological prognosis classification of patients with neuroblastoma using computational pathology analysis	64
DNA protein binding recognition based on lifelong learning	64
Dynamic modeling of antibody repertoire reshaping in response to viral infections	64
PrimePatNet87: Prime pattern and tunable q-factor wavelet transform techniques for automated accurate EEG emotion recognition	63
Impact of workflow variability on image-based intracranial aneurysm hemodynamics	63
A multi-granularity convolutional neural network model with temporal information and attention mechanism for efficient diabetes medical cost prediction	62
Systematic comparison of genome information processing and boundary recognition tools used for genomic island detection	62
Identification of key candidate genes and biological pathways in neuropathic pain	62
Enhanced single-cell RNA-seq embedding through gene expression and data-driven gene-gene interaction integration	61
A novel mTOR-associated gene signature for predicting prognosis and evaluating tumor immune microenvironment in lung adenocarcinoma	61
Design and hierarchical analysis of magnetic actuated robot: A governing equation based approach	61
A conversational agent for querying Italian Patient Information Leaflets and improving health literacy	61
The detection of mild traumatic brain injury in paediatrics using artificial neural networks	60
Enhanced breast mass segmentation in mammograms using a hybrid transformer UNet model	59
Editorial Board	59
Torque modulation mechanism of the knee joint during balance recovery	59
Sterenin M as a potential inhibitor of SARS-CoV-2 main protease identified from MeFSAT database using molecular docking, molecular dynamics simulation and binding free energy calculation	59
SPMLD: A skin pathological image dataset for non-melanoma with detailed lesion area annotation	59
Classifying alkaliphilic proteins using embeddings from protein language model	59
PIPE-Net: A pyramidal-input-parallel-encoding network for the segmentation of corneal layer interfaces in OCT images	59
Two-stage data augmentation for improved ASR performance for dysarthric speech	59
Bone marrow sparing oriented multi-model image registration in cervical cancer radiotherapy	58
A novel virtual robotic platform for controlling six degrees of freedom assistive devices with body-machine interfaces	58
Prediction of drug-target interactions via neural tangent kernel extraction feature matrix factorization model	58
Enclosing 95% confidence area and volume to center of pressure and center of mass in posturography using optimization algorithm and coordinate ascent methods	58
Cancer-inspired genomics mapper model for the generation of synthetic DNA sequences with desired genomics signatures	58
A wrapper method for finding optimal subset of multimodal Magnetic Resonance Imaging sequences for ischemic stroke lesion segmentation	58
Metagenome comparison (MC): A new framework for detecting unique/enriched OMUs (operational metagenomic units) derived from whole-genome sequencing reads	57
A mathematical model of tissue axial and radial diffusion in the microvasculature for intravascular microscopy and phosphorescence quenching data	57
Evaluation of Cellpose segmentation with sequential thresholding for instance segmentation of cytoplasms within autofluorescence images	57
Characterization of cancer subtypes associated with clinical outcomes by multi-omics integrative clustering	57
Computational identification of repurposed drugs against viruses causing epidemics and pandemics via drug-target network analysis	56
Patient-specific investigation into plaque rupture risk due to catheter tracking during TAVR	56
Intelligent tuberculosis activity assessment system based on an ensemble of neural networks	56
Wearable multisource quantitative gait analysis of Parkinson's diseases	56
Analysis and design of antithetic proportional-integral-derivative biocontrol-systems with species dilution	56
Alcohol patch test with hue-saturation-value model analysis predicts ALDH2 genetic polymorphism	56
Structural and functional analysis of disease-associated mutations in GOT1 gene: An in silico study	56
Direct parametric reconstruction in dynamic PET using deep image prior and a novel parameter magnification strategy	56
Novel classification of brain vascular tortuosity measures: A systematic review	55
Genomic instability-related twelve-microRNA signatures for predicting the prognosis of gastric cancer	55
Hemodynamics indicates differences between patients with and without a stroke outcome after left ventricular assist device implantation	55
Breast cancer detection and classification: A study on the specification and implementation of multilayer perceptron analog artificial neural networks	55
A novel multi-objective metaheuristic algorithm for protein-peptide docking and benchmarking on the LEADS-PEP dataset	55
A robust time delay estimation method for ultrasonic echo signals and elastography	55
A regularization method to improve adversarial robustness of neural networks for ECG signal classification	55
An adaptive language model-based intelligent medication assistant for the decision support of antidepressant prescriptions	55
A sleep staging model on wavelet-based adaptive spectrogram reconstruction and light weight CNN	55
Deep networks for behavioral variant frontotemporal dementia identification from multiple acquisition sources	55