Computers in Biology and Medicine

Article	Citations
Editorial Board	472
Editorial Board	416
Diffuse tumors: Molecular determinants shared by different cancer types	373
Identifying indications for novel drugs using electronic health records	321
Carotid single- and dual-layer stents reduce the wall adhesion of platelets by influencing flow and cellular transport	309
Pathogenicity classification of missense mutations based on deep generative model	290
Pedicle drilling force control of a robotic surgical system via spine-soft tissue coupling model and parameters optimization	287
A partially shared joint clustering framework for detecting protein complexes from multiple state-specific signed interaction networks	286
S2FLNet: Hepatic steatosis detection network with body shape	272
Automated identification of patient subgroups: A case-study on mortality of COVID-19 patients admitted to the ICU	263
Contrastive learning based method for X-ray and CT registration under surgical equipment occlusion	252
A self-supervised COVID-19 CT recognition system with multiple regularizations	252
Development and validation of a neutrophil extracellular traps-related gene signature for lower-grade gliomas	242
Causal relationship between slow waves of arterial, intracranial pressures and blood velocity in brain	236
Multiscale differential geometry learning of networks with applications to single-cell RNA sequencing data	228
Eye movement analysis for real-world settings using segmented linear regression	225
Advances in disease detection through retinal imaging: A systematic review	224
Longitudinal dementia trajectories for Alzheimer’s Disease characterization and prediction	215
Deriving a suitable schedule through robust H	214
Towards a better understanding of TF-DNA binding prediction from genomic features	214
Identification of lncRNA associated with the SERPINE1 gene in colorectal cancer through TGF-β pathway	204
Analysis of COVID-19 pandemic in USA, using Topological Weighted Centroid	203
Adaptive nonlinear filtering algorithms for removal of non-stationary noise in electronystagmographic signals	188
Class-Specific Distribution Alignment for semi-supervised medical image classification	184
Discrete element method-based simulation system for predicting natural stone evacuation pathways in patients with urolithiasis	182

Evaluation of the mechanical behaviour of the expandable wedge locked nail fixation in retrograde use: A finite element study	180
A novel mobile phone and tablet application for automatized calculation of pain extent	168
In silico evaluation of lattice designs for additively manufactured total hip implants	167
Improved predictive diagnosis of diabetic macular edema based on hybrid models: An observational study	166
Counting on AR: EEG responses to incongruent information with real-world context	162
A general sample-weighted framework for epileptic seizure prediction	161
Uniqueness of inspiratory airflow patterns in a realistic rat nasal cavity	160
CauDR: A causality-inspired domain generalization framework for fundus-based diabetic retinopathy grading	151
Two-stage error detection to improve electron microscopy image mosaicking	150
JoCoRank: Joint correlation learning with ranking similarity regularization for imbalanced fetal brain age regression	149
Editorial Board	148
Corrigendum to “Unraveling the molecular landscape of non-small cell lung cancer: Integrating bioinformatics and statistical approaches to identify biomarkers and drug repurposing” [Comput. Biol. Med.	146
Drug repositioning for rosacea disease: Biological TARGET identification, molecular docking, pharmacophore mapping, and molecular dynamics analysis	145
Predictive modeling for early detection of biliary atresia in infants with cholestasis: Insights from a machine learning study	145
Mass diffusion in multi-layer systems: an electrical analogue modelling approach	144
Prediction of colorectal cancer based on taxonomic levels of microorganisms and discovery of taxonomic biomarkers using the Grouping-Scoring-Modeling (G-S-M) approach	143
Deep-learning-based real-time individualization for reduce-order haemodynamic model	142
Electroanatomical mapping of the stomach with simultaneous biomagnetic measurements	142
Identification of anti-cancer organometallic compounds by inhibition of BCL-2/Bax interactions	140
Vectorial-based analysis of dual-tracer PET imaging: A proof of concept	139
Dual-Stream Subspace Clustering Network for revealing gene targets in Alzheimer's disease	139
A Three-branch Jointed Feature and Topology Decoder guided by game-theoretic interactions for temporomandibular joint segmentation	138
Insights from explainable AI in oesophageal cancer team decisions	136
Semi-empirical Anticoagulation Model (SAM): Dose prediction during warfarin therapy	134
LSDVvac: An immunoinformatics database for vaccine design against lumpy skin disease virus	134
Gene-related Parkinson's disease diagnosis via feature-based multi-branch octave convolution network	134
Enhancing and advancements in deep learning for melanoma detection: A comprehensive review	131
Disclosing neonatal pain in real-time: AI-derived pain sign from continuous assessment of facial expressions	128
SSMT-PANBERT: A single-stage multitask model for phenotype extraction and assertion negation detection in unstructured clinical text	126
SURVS: A Swin-Unet and game theory-based unsupervised segmentation method for retinal vessel	123
Automatic segmentation of intraluminal thrombosis of abdominal aortic aneurysms from CT angiography using a mixed-scale-driven multiview perception network (M2Net) model	122
Prediction of protein N-terminal acetylation modification sites based on CNN-BiLSTM-attention model	121
Enhancing cell instance segmentation in scanning electron microscopy images via a deep contour closing operator	120
ILSHIP: An interpretable and predictive model for hypothyroidism	120
Drug repurposing of triazoles against mucormycosis using molecular docking: A short communication	119
Non-same-scale feature attention network based on BPD for medical image segmentation	118
Analysis of domain shift in whole prostate gland, zonal and lesions segmentation and detection, using multicentric retrospective data	117
Integrating CNN and Bi-LSTM for protein succinylation sites prediction based on Natural Language Processing technique	115
Novel ensemble of optimized CNN and dynamic selection techniques for accurate Covid-19 screening using chest CT images	115
Classical Simulations on Quantum Computers: Interface-Driven Peptide Folding on Simulated Membrane Surfaces	114
Quantitative computed tomography imaging-based classification of cement dust-exposed subjects with an artificial neural network technique	114
Single-channel EEG based insomnia detection with domain adaptation	114
MulStack: An ensemble learning prediction model of multilabel mRNA subcellular localization	114
You get the best of both worlds? Integrating deep learning and traditional machine learning for breast cancer risk prediction	114
An efficient model for extracting respiratory and blood oxygen saturation data from photoplethysmogram signals by removing motion artifacts using heuristic-aided ensemble learning model	113
Data-driven discovery of sparse dynamical model of cardiovascular system for model predictive control	113
DRBpred: A sequence-based machine learning method to effectively predict DNA- and RNA-binding residues	113
Quantifying the influence of combined lung and kidney support using a cardiovascular model and sensitivity analysis-informed parameter identification	112
AIScholar: An OpenFaaS-enhanced cloud platform for intelligent medical data analytics	111
Detecting IDH and TERTp mutations in diffuse gliomas using 1H-MRS with attention deep-shallow networks	111

Computer models evaluating hand tremors in Parkinson's disease patients	110
Artificial vascular image generation using blood vessel texture maps	109
Hemodynamic alternations following stent deployment and post-dilation in a heavily calcified coronary artery: In silico and ex-vivo approaches	109
Integrating biocomputational techniques for Breast cancer drug discovery via the HER-2, BCRA, VEGF and ER protein targets	108
AGNet: Automatic generation network for skin imaging reports	105
Triage and monitoring of COVID-19 patients in intensive care using unsupervised machine learning	105
Potential inhibitors of the main protease of SARS-CoV-2 and modulators of arachidonic acid pathway: Non-steroidal anti-inflammatory drugs against COVID-19	104
Context-aggregator: An approach of loss- and class imbalance-aware aggregation in federated learning	104
Stack-AAgP: Computational prediction and interpretation of anti-angiogenic peptides using a meta-learning framework	104
KNU-DTI: KNowledge United Drug-Target Interaction prediction	103
Deep learning and machine learning approaches to classify stomach distant metastatic tumors using DNA methylation profiles	102
Reversing skin cancer adversarial examples by multiscale diffusive and denoising aggregation mechanism	102
FCSU-Net: A novel full-scale Cross-dimension Self-attention U-Net with collaborative fusion of multi-scale feature for medical image segmentation	101
Identifying fetal status with fetal heart rate: Deep learning approach based on long convolution	101
Hybrid offline and self-knowledge distillation for acute ischemic stroke lesion segmentation from non-contrast CT scans	100
Insights into potential mechanisms of asthma patients with COVID-19: A study based on the gene expression profiling of bronchoalveolar lavage fluid	99
Enhancing targeted tumor treatment: A novel fuzzy logic framework for precision drug delivery strategy selection	99
Fine-grained food image classification and recipe extraction using a customized deep neural network and NLP	99
Dynamic topography analysis of the cornea and its application to the diagnosis of keratoconus	98
Graph neural network-based subgraph analysis for predicting adverse drug events	97
Multi-constraint point set registration with redundant point removal for the registration of coronary arteries	96
AELGNet: Attention-based Enhanced Local and Global Features Network for medicinal leaf and plant classification	96
Mapping synthetic binding proteins epitopes on diverse protein targets by protein structure prediction and protein-protein docking	96
Automated mitral inflow Doppler peak velocity measurement using deep learning	95
Pharmacophore-guided computational modeling of quinolone-ATPase conjugate inhibitors targeting DNA GyrB subunit of Staphylococcus aureus	95
Automated tool detection with deep learning for monitoring kinematics and eye-hand coordination in microsurgery	95
A systematic review on the state-of-the-art strategies for protein representation	94
Enhanced depression detection from speech using Quantum Whale Optimization Algorithm for feature selection	93
Computational prediction of protein folding rate using structural parameters and network centrality measures	92
Synergistic eigenanalysis of covariance and Hessian matrices for enhanced binary classification on health datasets	92
Red blood cell passage through deformable interendothelial slits in the spleen: Insights into splenic filtration and hemodynamics	92
Molecular modelling and experimental validation identified a new therapeutic inhibitor of toxoplasmosis	92
Prediction of lung cancer metastasis by gene expression	91
Discrepancy-based diffusion models for lesion detection in brain MRI	90
A comprehensive analysis of single-cell RNA transcriptome reveals unique SPP1+ chondrocytes in human osteoarthritis	90
Temporal relative transformer encoding cooperating with channel attention for EEG emotion analysis	89
Development of closed-loop modelling framework for adaptive respiratory pacemakers	89
Beyond accuracy: The need for explainable AI in biomedical voice technology	88
EpiTEAmDNA: Sequence feature representation via transfer learning and ensemble learning for identifying multiple DNA epigenetic modification types across species	88
KS-TMIL: A K-Stage Transformer approach with multiple instance learning model for ovarian cancer subtype classification	86
M3-Net++: A multi-scale, multi-level, multi-stream network for nuclei segmentation in breast cancer histopathology using hierarchical context extraction and hybrid loss optimization	86
Numerical analysis of coil designs to expedite fracture healing using dielectrophoresis with S method	86
Anemia prediction using gene expression programming (GEP) and explainable artificial intelligence approaches	85
A novel Harris Hawks Optimization-based clustering method for elucidating genetic associations in osteoarthritis and Diverse Cancer Types	84
Conditional GAN based augmentation for predictive modeling of respiratory signals	84
KC-UNIT: Multi-kernel conversion using unpaired image-to-image translation with perceptual guidance in chest computed tomography imaging	84
Hierarchical cumulative network for unsupervised medical image registration	84
Optimization of deep learning models for inference in low resource environments	84
Performance of multilabel machine learning models and risk stratification schemas for predicting stroke and bleeding risk in patients with non-valvular atrial fibrillation	83
Artificial intelligence for identification of candidates for device-aided therapy in Parkinson's disease: DELIST-PD study	83
Unraveling the complexities of pathological voice through saliency analysis	82
Identification of JUN as determinant of osteoarthritis and its inhibition by the Chinese herbal formulae Zhuanggu Huoxue Tang	82
The role of the extracellular matrix in the reduction of lateral force transmission in muscle bundles: A finite element analysis	82
Wearable-based human flow experience recognition enhanced by transfer learning methods using emotion data	82
Visual prior-based cross-modal alignment network for radiology report generation	82
Automatic eczema classification in clinical images based on hybrid deep neural network	82
How CLSPN could demystify its prognostic value and potential molecular mechanism for hepatocellular carcinoma: A crosstalk study	81
An improved RIME optimization algorithm for lung cancer image segmentation	81
Predicting lung cancer survival based on clinical data using machine learning: A review	81
DE-JANet: A unified network based on dual encoder and joint attention for Alzheimer’s disease classification using multi-modal data	81
Artificial intelligence techniques for prediction of drug synergy in malignant diseases: Past, present, and future	80
CARES: A Corpus for classification of Spanish Radiological reports	80
Automated mitral valve segmentation in PLAX-view transthoracic echocardiography for anatomical assessment and risk stratification	79
Performance optimization of differential evolution with slime mould algorithm for multilevel breast cancer image segmentation	79
The role of mechano-electric feedbacks and hemodynamic coupling in scar-related ventricular tachycardia	79
Modelling of thrombus formation, growth and embolisation in the left atrial appendage under atrial fibrillation	78
Identifying potent natural inhibitors of the hepatitis C virus NS3 protein using multiple computational and molecular approaches	78
Exploring the spike glycoprotein-encoding gene of SARS-CoV-2 using multifractal analysis: Unveiling structural complexity and implications for viral transmission	78
Predicting diameter and tensile strength of electrospun fibers for biomedicine: A comparison of Box-Behnken design, traditional machine learning and deep learning	78
Extinction and stationary distribution of a stochastic COVID-19 epidemic model with time-delay	77
Assessing clinical utility of machine learning and artificial intelligence approaches to analyze speech recordings in multiple sclerosis: A pilot study	77
REDDA: Integrating multiple biological relations to heterogeneous graph neural network for drug-disease association prediction	77
HOTGpred: Enhancing human O-linked threonine glycosylation prediction using integrated pretrained protein language model-based features and multi-stage feature selection approach	77
The role and potential of computer-aided drug discovery strategies in the discovery of novel antimicrobials	76
COVID-19 diagnosis using state-of-the-art CNN architecture features and Bayesian Optimization	76
MCA-net: A multi-task channel attention network for Myocardial infarction detection and location using 12-lead ECGs	76
GasHisSDB: A new gastric histopathology image dataset for computer aided diagnosis of gastric cancer	76
A review of deep learning-based information fusion techniques for multimodal medical image classification	75
A robust drug recall supply chain management system using hyperledger blockchain ecosystem	75
A deep learning based model using RNN-LSTM for the Detection of Schizophrenia from EEG data	74

Efficient sleep apnea detection using single-lead ECG: A CNN-Transformer-LSTM approach	74
D-glucose-conjugated thioureas containing 2-aminopyrimidine as potential multitarget inhibitors for type 2 diabetes mellitus: Synthesis and biological activity study	74
A deep learning model combining convolutional neural networks and a selective kernel mechanism for SSVEP-Based BCIs	73
Structure, sensing and control of pneumatic upper limb rehabilitation system: Review and prospect	73
Dynamical pattern of successive bits to predict the outcomes of the SSRI and rTMS depression therapies using EEG signals	73
A mask R-CNN based automatic assessment system for nail psoriasis severity	72
Identification of potential agonist-like molecules for α2-adrenergic receptor by multi-layer virtual screening to combat sinusitis	72
Multi-label classification of fundus images with graph convolutional network and LightGBM	72
Personalized brachytherapy dose reconstruction using deep learning	72
A computational model of the effects of macronutrients absorption and physical exercise on hormonal regulation and metabolic homeostasis	72
Structure-based design of promising natural products to inhibit thymidylate kinase from Monkeypox virus and validation using free energy calculations	71
IVD fibrosis and disc collapse comprehensively aggravate vertebral body disuse osteoporosis and zygapophyseal joint osteoarthritis by posteriorly shifting the load transmission pattern	71
Emotion recognition in EEG signals using deep learning methods: A review	71
Prostate158 - An expert-annotated 3T MRI dataset and algorithm for prostate cancer detection	71
A method for predicting linear and conformational B-cell epitopes in an antigen from its primary sequence	71
Context encoder transfer learning approaches for retinal image analysis	70
Thyroid region prior guided attention for ultrasound segmentation of thyroid nodules	70
DrugormerDTI: Drug Graphormer for drug–target interaction prediction	70
Simulated annealing aided genetic algorithm for gene selection from microarray data	70
Effect of tumor heterogeneity on enhancing drug delivery to vascularized tumors using thermo-sensitive liposomes triggered by hyperthermia: A multi-scale and multi-physics computational model	69
An efficient image segmentation method for skin cancer imaging using improved golden jackal optimization algorithm	69
Dynamic Statistical Attention-based lightweight model for Retinal Vessel Segmentation: DyStA-RetNet	69
Sparse Dynamic Volume TransUNet with multi-level edge fusion for brain tumor segmentation	68
Identification of molecular and cellular infection response biomarkers associated with anthrax infection through comparative analysis of gene expression data	68
A transformer-based deep neural network for arrhythmia detection using continuous ECG signals	68
A novel hybrid ViT-LSTM model with explainable AI for brain stroke detection and classification in CT images: A case study of Rajshahi region	68
Functional identification and prediction of lncRNAs in esophageal cancer	68
Transcriptome analysis displays new molecular insights into the mechanisms of action of Mebendazole in gastric cancer cells	68
Molecular hybridization assisted multi-technique approach for designing USP21 inhibitors to halt catalytic triad-mediated nucleophilic attack and suppress pancreatic ductal adenocarcinoma progression:	67
Smoke veil prior regularized surgical field desmoking without paired in-vivo data	67
PNMC: Four-dimensional conebeam CT reconstruction combining prior network and motion compensation	67
A computational framework to simulate the thermochemical process during thermochemical ablation of biological tissues	67
Interplay of mutations, alternate mechanisms, and treatment breaks in leukaemia: Understanding and implications studied with stochastic models	67
Exploring molecular mechanisms of diazinon toxicity in HT22 hippocampal neurons through integrated miRNA and mRNA profiling	67
Impact of physiological loads of arterial wall on nucleus deformation in endothelial cells: A computational study	67
Validation of fluid-structure interaction simulations of the opening phase of phantom mitral heart valves under physiologically inspired conditions	67
Privacy preserving distributed learning classifiers – Sequential learning with small sets of data	66
FIM: A fatigued-injured muscle model based on the sliding filament theory	66
Identification of a novel gene signature for the prognosis of sepsis	66
Characterizing patients at higher cardiovascular risk for prescribed stimulants: Learning from health records data with predictive analytics and data mining techniques	65
A computational optimization study of a self-expandable transcatheter aortic valve	65
Ce	65
Deep learning image registration for cardiac motion estimation in adult and fetal echocardiography via a focus on anatomic plausibility and texture quality of warped image	65
Estimation of potassium levels in hemodialysis patients by T wave nonlinear dynamics and morphology markers	64
CFD simulations of inhalation through a subject-specific human larynx – Impact of the unilateral vocal fold immobility	64
Cross attention guided multi-scale feature fusion for false-positive reduction in pulmonary nodule detection	64
Role of [18F]-PSMA-1007 PET radiomics for seminal vesicle invasion prediction in primary prostate cancer	63
Computationally efficient model to predict the deformations of a cellular foot orthotic	63
Three-dimensional morphology scoring of hepatocellular carcinoma stratifies prognosis and immune infiltration	63
Joint cardiac tissue conductivity and activation time estimation using confirmatory factor analysis	62
Dynamic modeling of antibody repertoire reshaping in response to viral infections	62
A multi-granularity convolutional neural network model with temporal information and attention mechanism for efficient diabetes medical cost prediction	62
Collaborative networks of transformers and convolutional neural networks are powerful and versatile learners for accurate 3D medical image segmentation	62
DNA protein binding recognition based on lifelong learning	62
SPMLD: A skin pathological image dataset for non-melanoma with detailed lesion area annotation	61
A novel mTOR-associated gene signature for predicting prognosis and evaluating tumor immune microenvironment in lung adenocarcinoma	61
Combination of 2D and 3D nnU-Net for ground glass opacity segmentation in CT images of Post-COVID-19 patients	60
PrimePatNet87: Prime pattern and tunable q-factor wavelet transform techniques for automated accurate EEG emotion recognition	60
Medical application of deep-learning-based head pose estimation from RGB image sequence	60
Impact of workflow variability on image-based intracranial aneurysm hemodynamics	59
Pathological prognosis classification of patients with neuroblastoma using computational pathology analysis	59
A mechanobiological model for tumor spheroid evolution with application to glioblastoma: A continuum multiphysics approach	59
Torque modulation mechanism of the knee joint during balance recovery	59
Automatic segmentation and classification of Papanicolaou-stained cells and dataset for oral cancer detection	59
QMaxViT-Unet+: A query-based MaxViT-Unet with edge enhancement for scribble-supervised segmentation of medical images	59
Design and hierarchical analysis of magnetic actuated robot: A governing equation based approach	59
Two-stage data augmentation for improved ASR performance for dysarthric speech	59
Enhanced single-cell RNA-seq embedding through gene expression and data-driven gene-gene interaction integration	59
Artificial intelligence derived categorizations significantly improve HOMA IR/β indicators: Combating diabetes through cross-interacting drugs	59
Enhancing nuclei segmentation in breast histopathology images using U-Net with backbone architectures	58
A novel multi-objective metaheuristic algorithm for protein-peptide docking and benchmarking on the LEADS-PEP dataset	58
Spatiotemporal modeling of host–pathogen interactions using level-set method	58
Lightweight triangular mesh deformable reconstruction for low quality 3D organ models: Thickness noise and uneven topology	58
Dental measurement procedure based on 3D analysis and data processing	57
A Decision Support System Based on multi-head convolutional and Recurrent Neural Networks for assisting physicians in diagnosing ADHD	57
Editorial Board	57
Enhancing search strategies for systematic reviews on drug Harms: An evaluation of the utility of ChatGPT in error detection and keyword generation	57
MicroRNA regulation of PPARG Signalling: Therapeutic implications for pulmonary hypertension	57
GeneDX-PBMC: An adversarial autoencoder framework for unlocking Alzheimer's disease biomarkers using blood single-cell RNA sequencing data	56
Deep learning based classification of multi-label chest X-ray images via dual-weighted metric loss	56
Genetic algorithm based image reconstruction applying the digital holography process with the Discrete Orthonormal Stockwell Transform technique for diagnosis of COVID-19	56
An overview of artificial intelligence techniques for diagnosis of Schizophrenia based on magnetic resonance imaging modalities: Methods, challenges, and future works	56
Systematic comparison of genome information processing and boundary recognition tools used for genomic island detection	56
SLT-Net: A codec network for skin lesion segmentation	56
PIPE-Net: A pyramidal-input-parallel-encoding network for the segmentation of corneal layer interfaces in OCT images	55
An adaptive language model-based intelligent medication assistant for the decision support of antidepressant prescriptions	55
Genomic instability-related twelve-microRNA signatures for predicting the prognosis of gastric cancer	55
Precision oncology informatics for anticancer drug combination responses: A systematic review	55
A robust time delay estimation method for ultrasonic echo signals and elastography	55
A lightweight convolutional neural network hardware implementation for wearable heart rate anomaly detection	54
A bidirectional registration neural network for cardiac motion tracking using cine MRI images	54
Attention2Minority: A salient instance inference-based multiple instance learning for classifying small lesions in whole slide images	54
Identification of telomere-associated gene signatures to predict prognosis and drug sensitivity in glioma	54
Effective fall detection and post-fall breath rate tracking using a low-cost CW Doppler radar sensor	54
Atten-Nonlocal Unet: Attention and Non-local Unet for medical image segmentation	54