Computers in Biology and Medicine

Article	Citations
Two dimensional computational model coupling myoarchitecture-based lingual tissue mechanics with liquid bolus flow during oropharyngeal swallowing	726
A graph neural network approach for predicting drug susceptibility in the human microbiome	380
Editorial Board	342
The effects of aperture position and length in side-vented needles on root canal irrigation: A computational fluid dynamics study	299
Interpretable machine learning for dermatological disease detection: Bridging the gap between accuracy and explainability	262
A dual-encoder double concatenation Y-shape network for precise volumetric liver and lesion segmentation	255
Identification of new targets for glioblastoma therapy based on a DNA expression microarray	245
Identification of anti-cancer organometallic compounds by inhibition of BCL-2/Bax interactions	241
Exploring the therapeutic potential of Rhododendron anthopogon D.Don essential oil constituents against lung cancer: A network pharmacology-based analysis with molecular docking and experimental studi	239
Rim learning framework based on TS-GAN: A new paradigm of automated glaucoma screening from fundus images	226
Comparison by partition—Finding Petri nets similarity on the basis of subnets	203
MUC1 and MUC4 expression are inversely correlated and trigger immunological response and transport pathways in adult-type diffuse gliomas	203
Multi-modality medical image classification with ResoMergeNet for cataract, lung cancer, and breast cancer diagnosis	201
Numerical assessment of the performance of a new multi side-hole catheter design in liver radioembolization	198
BTSegDiff: Brain tumor segmentation based on multimodal MRI Dynamically guided diffusion probability model	192
Quantifying the influence of combined lung and kidney support using a cardiovascular model and sensitivity analysis-informed parameter identification	189
An interactive visualization dashboard for predicting the effect of sacubitril/valsartan initiation in patients with heart failure	188
Synthesized colonoscopy dataset from high-fidelity virtual colon with abnormal simulation	187
An efficient heuristic for geometric analysis of cell deformations	185
Integrating CNN and Bi-LSTM for protein succinylation sites prediction based on Natural Language Processing technique	167
Ten Meter Walk Test for motor function assessment with technological devices based on lower members’ movements: A systematic review	164
You get the best of both worlds? Integrating deep learning and traditional machine learning for breast cancer risk prediction	163
Integrative functional logistic regression model for genome-wide association studies	163
Critical methodological factors influencing the accuracy of intraoral scanners in digital dentistry research	162
Towards real-world wearable sleepiness detection: Electrodermal activity data during speech can identify sleep deprivation	156

Database, prediction, and antibacterial research of astringency based on large language models	154
Automatic discrimination between neuroendocrine carcinomas and grade 3 neuroendocrine tumors by deep learning of H&E images	148
AELGNet: Attention-based Enhanced Local and Global Features Network for medicinal leaf and plant classification	144
SmartHypnos: An Android application for low-cost sleep self-monitoring and personalized recommendation generation	143
Hemodynamic microenvironment of coronary stent strut malapposition	141
Design of a multi-epitope vaccine candidate against carrion disease by immunoinformatics approach	140
Discrete element method-based simulation system for predicting natural stone evacuation pathways in patients with urolithiasis	136
Detection of retinal diseases using an accelerated reused convolutional network	133
Using the coefficient of determination to identify injury regions after stroke in pre-clinical FDG-PET images	133
Unraveling the relapse-associated landscape and individualized therapy in stage I lung adenocarcinoma based on immune and mitochondrial metabolism hallmarks via multi-omics analyses	132
Gait asymmetry assessment through Eigen-Gait components on dissimilarity maps	132
Disentangled representational learning for anomaly detection in single-lead electrocardiogram signals using variational autoencoder	131
Kinematic classification of mandibular movements in patients with temporomandibular disorders based on PCA	130
Out-of-distribution detection in digital pathology: Do foundation models bring the end to reconstruction-based approaches?	128
Neural network procedures for the cholera disease system with public health mediations	128
Evaluation of N-palmitoylethanolamine (PEA) binding to nuclear receptors through docking and molecular dynamics studies	127
Stress classification with in-ear heartbeat sounds	124
AIScholar: An OpenFaaS-enhanced cloud platform for intelligent medical data analytics	124
Patch-based feature mapping with generative adversarial networks for auxiliary hip fracture detection	123
RetinaRegNet: A zero-shot approach for retinal image registration	120
Detecting IDH and TERTp mutations in diffuse gliomas using 1H-MRS with attention deep-shallow networks	120
ATEDU-NET: An Attention-Embedded Deep Unet for multi-disease diagnosis in chest X-ray images, breast ultrasound, and retina fundus	120
ManiNeg: Manifestation-guided multimodal pretraining for mammography screening	120
ABIET: An explainable transformer for identifying functional groups in biological active molecules	118
Deep learning for predicting respiratory rate from biosignals	118
Structural probing of HapR to identify potent phytochemicals to control Vibrio cholera through integrated computational approaches	118
Breast cancer detection from thermal images using a Grunwald-Letnikov-aided Dragonfly algorithm-based deep feature selection method	117
Continuous online prediction of lower limb joints angles based on sEMG signals by deep learning approach	117
A feature-aware multimodal framework with auto-fusion for Alzheimer’s disease diagnosis	116
Drug repositioning and experimental validation for targeting ZZ domain of p62 as a cancer treatment	115
Real-time adaptive proton therapy: An AI-based spatio-temporal mono-energetic dose calculation model (CC-LSTM)	114
AI-MET: A deep learning-based clinical decision support system for distinguishing multisystem inflammatory syndrome in children from endemic typhus	114
X-scPAE: An explainable deep learning model for embryonic lineage allocation prediction based on single-cell transcriptomics revealing key genes in embryonic cell development	114
Active learning and margin strategies for arrhythmia classification in implantable devices	114
Development and validation of a neutrophil extracellular traps-related gene signature for lower-grade gliomas	113
A novel tool for multi-omics network integration and visualization: A study of glioma heterogeneity	113
Utilizing machine learning for predicting drug release from polymeric drug delivery systems	111
Development and clinical evaluation of an AI-assisted respiratory state classification system for chest X-rays: A BMI-Specific approach	110
Modular dynamics paradigm in biosystems multilevel modeling: Software design and PBPK/PD validation	109
Self-supervised learning for graph-structured data in healthcare applications: A comprehensive review	108
Advancements in protein structure prediction: A comparative overview of AlphaFold and its derivatives	108
Advancing personalized immunotherapy for melanoma: Integrating immunoinformatics in multi-epitope vaccine development, neoantigen identification via NGS, and immune simulation evaluation	108
A comprehensive survey of intestine histopathological image analysis using machine vision approaches	107
Virtual flow diverter deployment and embedding for hemodynamic simulations	106
Multimodal pre-screening can predict BCI performance variability: A novel subject-specific experimental scheme	106
MM-StackEns: A new deep multimodal stacked generalization approach for protein–protein interaction prediction	106
MGCBFormer: The multiscale grid-prior and class-inter boundary-aware transformer for polyp segmentation	104
Comparing deep learning-based automatic segmentation of breast masses to expert interobserver variability in ultrasound imaging	104
Automatic segmentation of intraluminal thrombosis of abdominal aortic aneurysms from CT angiography using a mixed-scale-driven multiview perception network (M2Net) model	103
Linear and nonlinear analysis of intrinsic mode function after facial stimuli presentation in children with autism spectrum disorder	102

Mapping synthetic binding proteins epitopes on diverse protein targets by protein structure prediction and protein-protein docking	101
Molecular docking-assisted investigation of Pd(II) complexes carrying “SNS” pincer-type pyridine-thioether ligand as potential drug candidates against COVID-19	100
Investigation of nonsynonymous mutations in the spike protein of SARS-CoV-2 and its interaction with the ACE2 receptor by molecular docking and MM/GBSA approach	100
Non-coding RNA identification with pseudo RNA sequences and feature representation learning	99
A bibliometric analysis of diffuse large B-cell lymphoma research from 2001 to 2020	99
Influence of the eye globe design on biomechanical analysis	99
Deep learning reveals lung shape differences on baseline chest CT between mild and severe COVID-19: A multi-site retrospective study	98
A novel mobile phone and tablet application for automatized calculation of pain extent	98
Modeling the protective role of human eyelashes against ultraviolet light exposure	98
SRTRP-Net: A multi-task learning network for segmentation and prediction of stereotactic radiosurgery treatment response in brain metastases	98
A retinal vessel segmentation network with multiple-dimension attention and adaptive feature fusion	97
An open-source, three-dimensional growth model of the mandible	97
CT-based generation of synthetic-pseudo MR images with different weightings for human knee	96
A robust drug recall supply chain management system using hyperledger blockchain ecosystem	96
Self-supervised learning-based cervical cytology for the triage of HPV-positive women in resource-limited settings and low-data regime	96
Liquid-liquid phase separation-related lncRNA prognostic signature and ZNF32-AS2 as a novel biomarker in hepatocellular carcinoma	95
Computational studies evidenced the potential of steroidal lactone to disrupt surface interaction of SARS-CoV-2 spike protein and hACE2	94
Discriminative kernel convolution network for multi-label ophthalmic disease detection on imbalanced fundus image dataset	93
A deep learning based model using RNN-LSTM for the Detection of Schizophrenia from EEG data	93
An accurate unsupervised extraction of retinal vasculature using curvelet transform and classical morphological operators	93
EAGMN: Coronary artery semantic labeling using edge attention graph matching network	92
Predicting the effect of a combination drug therapy on the prostate tumor growth via an improvement of a direct radial basis function partition of unity technique for a diffuse-interface model	92
A lightweight attention-driven YOLOv5m model for improved brain tumor detection	92
Computational exploration of novel ketoprofen derivatives: Molecular dynamics simulations and MM-PBSA calculations for COX-2 inhibition as promising anti-inflammatory drugs	91
AsthmaKGxE: An asthma–environment interaction knowledge graph leveraging public databases and scientific literature	91
RDmaster: A novel phenotype-oriented dialogue system supporting differential diagnosis of rare disease	91
An improved RIME optimization algorithm for lung cancer image segmentation	90
Plasma protein-based identification of neuroimage-driven subtypes in mild cognitive impairment via protein-protein interaction aware explainable graph propagational network	90
Maximizing matching, equity and survival in kidney transplantation using molecular HLA immunogenicity quantitation	90
Graph neural network-based subgraph analysis for predicting adverse drug events	90
Evaluation of the mechanical behaviour of the expandable wedge locked nail fixation in retrograde use: A finite element study	90
Adaptive nonlinear filtering algorithms for removal of non-stationary noise in electronystagmographic signals	89
A meta-learning approach to improving radiation response prediction in cancers	88
An evolutionary machine learning for multiple myeloma using Runge Kutta Optimizer from multi characteristic indexes	87
Screening of potent phytochemical inhibitors against SARS-CoV-2 protease and its two Asian mutants	87
Automatic eczema classification in clinical images based on hybrid deep neural network	86
Exploring the cuproptosis-related molecular clusters in the peripheral blood of patients with amyotrophic lateral sclerosis	86
Editorial Board	85
A bibliometric analysis of the cause of sudden unexplained death in forensic medicine: Research trends, hot spots and prospects	84
Large-scale analysis of neural activity and connectivity from high-density electroencephalographic data	84
MACG-Net: Multi-axis cross gating network for deformable medical image registration	84
OPTICS: An interactive online platform for photosensory and bio-functional proteins in optogenetic systems	83
Diffuse tumors: Molecular determinants shared by different cancer types	83
Biomechanical and histological changes associated with riboflavin ultraviolet-A-induced CXL with different irradiances in young human corneal stroma	83
GPT-4 as a biomedical simulator	82
Elicitation of fetal ECG from abdominal recordings using Blind Source Separation techniques and Robust Set Membership Affine Projection algorithm for signal quality enhancement	82
Dynamic PET image reconstruction incorporating a median nonlocal means kernel method	82
A fractional-order model for nosocomial infection caused by Pseudomonas aeruginosa in Northern Cyprus	81
Lipophagy-related gene RAB7A is involved in immune regulation and malignant progression in hepatocellular carcinoma	81
Insights into dietary phytochemicals targeting Parkinson's disease key genes and pathways: A network pharmacology approach	81
MulStack: An ensemble learning prediction model of multilabel mRNA subcellular localization	81
An enhanced Runge Kutta boosted machine learning framework for medical diagnosis	80
Flow patterns in ascending aortic aneurysms: Determining the role of hypertension using phase contrast magnetic resonance and computational fluid dynamics	80
Numerical assessment of hemodynamic perspectives of a left ventricular assist device and subsequent proposal for improvisation	80
Identification of potential agonist-like molecules for α2-adrenergic receptor by multi-layer virtual screening to combat sinusitis	80
WBC YOLO-ViT: 2 Way - 2 stage white blood cell detection and classification with a combination of YOLOv5 and vision transformer	79
Computational mechanobiology model evaluating healing of postoperative cavities following breast-conserving surgery	79
Prostate158 - An expert-annotated 3T MRI dataset and algorithm for prostate cancer detection	79
Emotion recognition in EEG signals using deep learning methods: A review	79
Privacy-preserving blockchain-based federated learning for brain tumor segmentation	78
GCNfold: A novel lightweight model with valid extractors for RNA secondary structure prediction	78
Altruistic seagull optimization algorithm enables selection of radiomic features for predicting benign and malignant pulmonary nodules	78
Using an artificial intelligence tool incorporating natural language processing to identify patients with a diagnosis of ANCA-associated vasculitis in electronic health records	78
VDA-RWLRLS: An anti-SARS-CoV-2 drug prioritizing framework combining an unbalanced bi-random walk and Laplacian regularized least squares	78
Enhancing cerebral arteriovenous malformation analysis: Development and application of patient-specific lumped parameter models based on 3D imaging data	78
Automated detection of ADHD: Current trends and future perspective	77
Enhanced depression detection from speech using Quantum Whale Optimization Algorithm for feature selection	77
An immunoinformatics-based designed multi-epitope candidate vaccine (mpme-VAC/STV-1) against Mycoplasma pneumoniae	77
Performance of multilabel machine learning models and risk stratification schemas for predicting stroke and bleeding risk in patients with non-valvular atrial fibrillation	76
ACP-check: An anticancer peptide prediction model based on bidirectional long short-term memory and multi-features fusion strategy	76
Automatic detection of stroke lesion from diffusion-weighted imaging via the improved YOLOv5	76
Feature selection methods on gene expression microarray data for cancer classification: A systematic review	76
Automatically recognize and segment morphological features of the 3D vertebra based on topological data analysis	75
Integrating biocomputational techniques for Breast cancer drug discovery via the HER-2, BCRA, VEGF and ER protein targets	75
Prediction of drug-target binding affinity based on deep learning models	75
Computational prediction of protein folding rate using structural parameters and network centrality measures	75
A new strategy to identify ADAM12 and PDGFRB as a novel prognostic biomarker for matrine regulates gastric cancer via high throughput chip mining and computational verification	75
Machine learning integrated ensemble of feature selection methods followed by survival analysis for predicting breast cancer subtype specific miRNA biomarkers	74
Alzheimer’s disease prediction algorithm based on de-correlation constraint and multi-modal feature interaction	74
Prediction of viral pneumonia based on machine learning models analyzing pulmonary inflammation index scores	74

Predictive modeling for early detection of biliary atresia in infants with cholestasis: Insights from a machine learning study	74
A mask R-CNN based automatic assessment system for nail psoriasis severity	74
Explainable deep learning diagnostic system for prediction of lung disease from medical images	73
Improved predictive diagnosis of diabetic macular edema based on hybrid models: An observational study	73
A multi-module algorithm for heartbeat classification based on unsupervised learning and adaptive feature transfer	73
SARS-CoV-2 NSP14 governs mutational instability and assists in making new SARS-CoV-2 variants	72
Voxel representation of brain images inpainting via Regional Pixel Semantic Network and pyramidal attention AE - Quantile differential mechanism model	71
An efficient model for extracting respiratory and blood oxygen saturation data from photoplethysmogram signals by removing motion artifacts using heuristic-aided ensemble learning model	71
Signal completion using generative adversarial networks for enhanced photoplethysmography measurement accuracy	70
Insights from explainable AI in oesophageal cancer team decisions	70
Customized T-time inner sampling network with uncertainty-aware data augmentation strategy for multi-annotated lesion segmentation	70
Aberrant migration features in primary skin fibroblasts of Huntington's disease patients hold potential for unraveling disease progression using an image based machine learning tool	70
FCSU-Net: A novel full-scale Cross-dimension Self-attention U-Net with collaborative fusion of multi-scale feature for medical image segmentation	70
The sample locator: A federated search tool for biosamples and associated data in Europe using HL7 FHIR	69
Characterization of cardiac resynchronization therapy response through machine learning and personalized models	69
Brain-GCN-Net: Graph-Convolutional Neural Network for brain tumor identification	68
Automated detection and classification of tumor histotypes on dynamic PET imaging data through machine-learning driven voxel classification	68
Editorial Board	68
Distributed management of patient data-sharing informed consents for clinical research	68
ℛSCZ: A Riemannian schizophrenia diagnosis framework based on the multiplexity of EEG-based dynamic functional connectivity patterns	68
Next-generation chemotherapy treatments based on black hole algorithms: From cancer remission to chronic disease management	67
Genome-wide transcriptomics and copy number profiling identify patient-specific CNV-lncRNA-mRNA regulatory triplets in colorectal cancer	67
Homologous recombination deficiency in triple-negative breast cancer: Multi-scale transcriptomics reveals distinct tumor microenvironments and limitations in predicting immunotherapy response	67
XGraphCDS: An explainable deep learning model for predicting drug sensitivity from gene pathways and chemical structures	67
ECLNet: Center localization of eye structures based on Adaptive Gaussian Ellipse Heatmap	67
ILSHIP: An interpretable and predictive model for hypothyroidism	67
Context encoder transfer learning approaches for retinal image analysis	67
Utilization of AlphaFold models for drug discovery: Feasibility and challenges. Histone deacetylase 11 as a case study	67
Self-supervised CT super-resolution with hybrid model	67
A privacy-aware method for COVID-19 detection in chest CT images using lightweight deep conventional neural network and blockchain	66
Classifying tumor brain images using parallel deep learning algorithms	66
Comparison of machine learning techniques for the identification of human activities from inertial sensors available in a mobile device after the application of data imputation techniques	66
Automatic heartbeat classification using S-shaped reconstruction and a squeeze-and-excitation residual network	66
A diagnostic model for COVID-19 based on proteomics analysis	66
LayNet—A multi-layer architecture to handle imbalance in medical imaging data	66
Extinction and stationary distribution of a stochastic COVID-19 epidemic model with time-delay	65
Machine learning and network-based models to identify genetic risk factors to the progression and survival of colorectal cancer	65
Improving deep learning-based automatic cranial defect reconstruction by heavy data augmentation: From image registration to latent diffusion models	64
Human body numerical simulation: An accurate model for a thigh subjected to a cold treatment	64
Mathematical modeling of COVID-19 pandemic in India using Caputo-Fabrizio fractional derivative	64
A scalable artificial intelligence platform that automatically finds copy number variations (CNVs) in journal articles and transforms them into a database: CNV extraction, transformation, and loading	64
LSCS-Net: A lightweight skin cancer segmentation network with densely connected multi-rate atrous convolution	63
Boosted federated learning based on improved Particle Swarm Optimization for healthcare IoT devices	63
Numerical analysis of stenoses severity and aortic wall mechanics in patients with supravalvular aortic stenosis	63
Enhancing cross-subject EEG emotion recognition through multi-source manifold metric transfer learning	63
The role and potential of computer-aided drug discovery strategies in the discovery of novel antimicrobials	63
A depthwise separable dense convolutional network with convolution block attention module for COVID-19 diagnosis on CT scans	63
Mathematical analysis and prediction of future outbreak of dengue on time-varying contact rate using machine learning approach	63
An improved faster R-CNN algorithm for assisted detection of lung nodules	62
Self-Distilled Supervised Contrastive Learning for diagnosis of breast cancers with histopathological images	62
SARS-CoV-2 Omicron spike glycoprotein receptor binding domain exhibits super-binder ability with ACE2 but not convalescent monoclonal antibody	61
Biomechanical analysis of functionally graded porous interbody cage for lumbar spinal fusion	61
Estradiol is a key candidate for treating Ankylosing Spondylolisthesis with Traditional Chinese Medicine	61
EG-Unet: Edge-Guided cascaded networks for automated frontal brain segmentation in MR images	60
Priority index for asthma (PIA): In silico discovery of shared and distinct drug targets for adult- and childhood-onset disease	60
Designing multi-epitope vaccine against Staphylococcus aureus by employing subtractive proteomics, reverse vaccinology and immuno-informatics approaches	60
Effects of 1Hz repetitive transcranial magnetic stimulation on autism with intellectual disability: A pilot study	60
Translational vaccinomics and structural filtration algorithm to device multiepitope vaccine for catastrophic monkeypox virus	60
Network pharmacology and LC-MS approachs to explore the active compounds and mechanisms of Yuanjiang decoction for treating bradyarrhythmia	60
SAFNet: A deep spatial attention network with classifier fusion for breast cancer detection	60
A reinforcement federated learning based strategy for urinary disease dataset processing	60
VECTOR: An algorithm for the detection of COVID-19 pneumonia from velcro-like lung sounds	59
Time-based self-supervised learning for Wireless Capsule Endoscopy	59
Modeling the effect of glucagon on endogenous glucose production in type 1 diabetes: On the role of glucagon receptor dynamics	59
Screening of natural compounds from Cyperus rotundus Linn against SARS-CoV-2 main protease (Mpro): An integrated computational approach	59
TUnet-LBF: Retinal fundus image fine segmentation model based on transformer Unet network and LBF	58
Quantifying the impact of Pyramid Squeeze Attention mechanism and filtering approaches on Alzheimer's disease classification	58
Computational fluid dynamics comparison of impaired breathing function in French bulldogs with nostril stenosis and an examination of the efficacy of rhinoplasty	58
Unraveling the complexities of pathological voice through saliency analysis	58
Real-time forecasting of exercise-induced fatigue from wearable sensors	58
Analysis of COVID-19 pandemic in USA, using Topological Weighted Centroid	58
EHDFL: Evolutionary hybrid domain feature learning based on windowed fast Fourier convolution pyramid for medical image classification	58
Computational design of phage cocktails based on phage-bacteria infection networks	58
Pharmacophore-guided computational modeling of quinolone-ATPase conjugate inhibitors targeting DNA GyrB subunit of Staphylococcus aureus	57
Tissue concepts: Supervised foundation models in computational pathology	57
Genetic analysis from multiple cohorts implies causality between 2200 druggable genes, telomere length, and leukemia	57
D-glucose-conjugated thioureas containing 2-aminopyrimidine as potential multitarget inhibitors for type 2 diabetes mellitus: Synthesis and biological activity study	57
Analysis of inoculation strategies during COVID-19 pandemic with an agent-based simulation approach	57
Enhancing sonothrombolysis outcomes with dual-frequency ultrasound: Insights from an in silico microbubble dynamics study	56
From farm to pharma: Investigation of the therapeutic potential of the dietary plants Apium graveolens L., Coriandrum sativum, and Mentha longifolia, as AhR modulators for Immunotherapy	56
Stratification of glioma based on stemness scores in bulk and single-cell transcriptomes	55
EEG power spectra parameterization and adaptive channel selection towards semi-supervised seizure prediction	55
Choroidal Layer Analysis in OCT images via Ambiguous Boundary-aware Attention	55
Deep learning and machine learning approaches to classify stomach distant metastatic tumors using DNA methylation profiles	55
The role of the extracellular matrix in the reduction of lateral force transmission in muscle bundles: A finite element analysis	55
Fine-grained food image classification and recipe extraction using a customized deep neural network and NLP	55
Enhancing gastric cancer early detection: A multi-verse optimized feature selection model with crossover-information feedback	55
Towards understanding post-COVID-19 condition: A systematic meta-analysis of transcriptomic alterations with sex-specific insights	55
Estimation of BMI from facial images using semantic segmentation based region-aware pooling	54
Sparse non-convex regularization based explainable DBN in the analysis of brain abnormalities in schizophrenia	54
Non-standard bioinformatics characterization of SARS-CoV-2	54
An emotion recognition method based on EWT-3D–CNN–BiLSTM-GRU-AT model	53
A novel self-learning framework for bladder cancer grading using histopathological images	53
Simulation of a new respiratory phase sorting method for 4D-imaging using optical surface information towards precision radiotherapy	53
Development of closed-loop modelling framework for adaptive respiratory pacemakers	53