Computers in Biology and Medicine

Article	Citations
Editorial Board	430
Editorial Board	385
Diffuse tumors: Molecular determinants shared by different cancer types	347
Functional identification and prediction of lncRNAs in esophageal cancer	295
Identifying indications for novel drugs using electronic health records	292
Hybrid offline and self-knowledge distillation for acute ischemic stroke lesion segmentation from non-contrast CT scans	279
Carotid single- and dual-layer stents reduce the wall adhesion of platelets by influencing flow and cellular transport	266
Identification of JUN as determinant of osteoarthritis and its inhibition by the Chinese herbal formulae Zhuanggu Huoxue Tang	252
Pathogenicity classification of missense mutations based on deep generative model	247
Pedicle drilling force control of a robotic surgical system via spine-soft tissue coupling model and parameters optimization	237
A partially shared joint clustering framework for detecting protein complexes from multiple state-specific signed interaction networks	231
S2FLNet: Hepatic steatosis detection network with body shape	225
Automated identification of patient subgroups: A case-study on mortality of COVID-19 patients admitted to the ICU	212
Contrastive learning based method for X-ray and CT registration under surgical equipment occlusion	210
Enhancing targeted tumor treatment: A novel fuzzy logic framework for precision drug delivery strategy selection	206
A self-supervised COVID-19 CT recognition system with multiple regularizations	204
Assessing clinical utility of machine learning and artificial intelligence approaches to analyze speech recordings in multiple sclerosis: A pilot study	202
Conditional GAN based augmentation for predictive modeling of respiratory signals	201
Multiscale differential geometry learning of networks with applications to single-cell RNA sequencing data	197
Causal relationship between slow waves of arterial, intracranial pressures and blood velocity in brain	194
How CLSPN could demystify its prognostic value and potential molecular mechanism for hepatocellular carcinoma: A crosstalk study	194
Development and validation of a neutrophil extracellular traps-related gene signature for lower-grade gliomas	188
Towards a better understanding of TF-DNA binding prediction from genomic features	185
D-glucose-conjugated thioureas containing 2-aminopyrimidine as potential multitarget inhibitors for type 2 diabetes mellitus: Synthesis and biological activity study	183
SURVS: A Swin-Unet and game theory-based unsupervised segmentation method for retinal vessel	177

A systematic review on the state-of-the-art strategies for protein representation	176
Longitudinal dementia trajectories for Alzheimer’s Disease characterization and prediction	166
Deriving a suitable schedule through robust H	166
Mapping synthetic binding proteins epitopes on diverse protein targets by protein structure prediction and protein-protein docking	165
Personalized brachytherapy dose reconstruction using deep learning	154
A computational model of the effects of macronutrients absorption and physical exercise on hormonal regulation and metabolic homeostasis	146
A method for predicting linear and conformational B-cell epitopes in an antigen from its primary sequence	145
Red blood cell passage through deformable interendothelial slits in the spleen: Insights into splenic filtration and hemodynamics	144
Eye movement analysis for real-world settings using segmented linear regression	143
The role and potential of computer-aided drug discovery strategies in the discovery of novel antimicrobials	142
Performance optimization of differential evolution with slime mould algorithm for multilevel breast cancer image segmentation	141
A novel Harris Hawks Optimization-based clustering method for elucidating genetic associations in osteoarthritis and Diverse Cancer Types	141
Analysis of COVID-19 pandemic in USA, using Topological Weighted Centroid	140
Non-same-scale feature attention network based on BPD for medical image segmentation	138
Adaptive nonlinear filtering algorithms for removal of non-stationary noise in electronystagmographic signals	138
Unraveling the complexities of pathological voice through saliency analysis	138
Graph neural network-based subgraph analysis for predicting adverse drug events	138
Reversing skin cancer adversarial examples by multiscale diffusive and denoising aggregation mechanism	136
Class-Specific Distribution Alignment for semi-supervised medical image classification	136
Discrete element method-based simulation system for predicting natural stone evacuation pathways in patients with urolithiasis	135
Evaluation of the mechanical behaviour of the expandable wedge locked nail fixation in retrograde use: A finite element study	135
A novel mobile phone and tablet application for automatized calculation of pain extent	134
CauDR: A causality-inspired domain generalization framework for fundus-based diabetic retinopathy grading	133
JoCoRank: Joint correlation learning with ranking similarity regularization for imbalanced fetal brain age regression	133
Two-stage error detection to improve electron microscopy image mosaicking	133
KNU-DTI: KNowledge United Drug-Target Interaction prediction	131
Editorial Board	131
Disclosing neonatal pain in real-time: AI-derived pain sign from continuous assessment of facial expressions	130
Corrigendum to “Unraveling the molecular landscape of non-small cell lung cancer: Integrating bioinformatics and statistical approaches to identify biomarkers and drug repurposing” [Comput. Biol. Med.	129
Deep learning and machine learning approaches to classify stomach distant metastatic tumors using DNA methylation profiles	129
Modelling of thrombus formation, growth and embolisation in the left atrial appendage under atrial fibrillation	127
Predictive modeling for early detection of biliary atresia in infants with cholestasis: Insights from a machine learning study	127
Drug repositioning for rosacea disease: Biological TARGET identification, molecular docking, pharmacophore mapping, and molecular dynamics analysis	126
Mass diffusion in multi-layer systems: an electrical analogue modelling approach	123
You get the best of both worlds? Integrating deep learning and traditional machine learning for breast cancer risk prediction	122
Prediction of colorectal cancer based on taxonomic levels of microorganisms and discovery of taxonomic biomarkers using the Grouping-Scoring-Modeling (G-S-M) approach	118
Deep-learning-based real-time individualization for reduce-order haemodynamic model	117
Prediction of lung cancer metastasis by gene expression	117
Automated mitral inflow Doppler peak velocity measurement using deep learning	114
Electroanatomical mapping of the stomach with simultaneous biomagnetic measurements	113
Multi-constraint point set registration with redundant point removal for the registration of coronary arteries	113
Vectorial-based analysis of dual-tracer PET imaging: A proof of concept	112
Identification of anti-cancer organometallic compounds by inhibition of BCL-2/Bax interactions	112
Context encoder transfer learning approaches for retinal image analysis	111
ILSHIP: An interpretable and predictive model for hypothyroidism	109
Dynamic topography analysis of the cornea and its application to the diagnosis of keratoconus	108
Development of closed-loop modelling framework for adaptive respiratory pacemakers	107
Dual-Stream Subspace Clustering Network for revealing gene targets in Alzheimer's disease	107
A Three-branch Jointed Feature and Topology Decoder guided by game-theoretic interactions for temporomandibular joint segmentation	106
Gene-related Parkinson's disease diagnosis via feature-based multi-branch octave convolution network	106

FCSU-Net: A novel full-scale Cross-dimension Self-attention U-Net with collaborative fusion of multi-scale feature for medical image segmentation	106
Insights from explainable AI in oesophageal cancer team decisions	106
Semi-empirical Anticoagulation Model (SAM): Dose prediction during warfarin therapy	105
LSDVvac: An immunoinformatics database for vaccine design against lumpy skin disease virus	105
Enhancing cell instance segmentation in scanning electron microscopy images via a deep contour closing operator	105
Computational prediction of protein folding rate using structural parameters and network centrality measures	104
AELGNet: Attention-based Enhanced Local and Global Features Network for medicinal leaf and plant classification	104
Synergistic eigenanalysis of covariance and Hessian matrices for enhanced binary classification on health datasets	104
Artificial intelligence for identification of candidates for device-aided therapy in Parkinson's disease: DELIST-PD study	103
Multi-label classification of fundus images with graph convolutional network and LightGBM	102
Improved predictive diagnosis of diabetic macular edema based on hybrid models: An observational study	102
A mask R-CNN based automatic assessment system for nail psoriasis severity	101
Counting on AR: EEG responses to incongruent information with real-world context	101
Automatic eczema classification in clinical images based on hybrid deep neural network	100
Dynamic Statistical Attention-based lightweight model for Retinal Vessel Segmentation: DyStA-RetNet	100
Identification of potential agonist-like molecules for α2-adrenergic receptor by multi-layer virtual screening to combat sinusitis	100
Blood glucose detection based on Teager-Kaiser main energy of photoacoustic signal	98
Fine-grained food image classification and recipe extraction using a customized deep neural network and NLP	98
Quantitative computed tomography imaging-based classification of cement dust-exposed subjects with an artificial neural network technique	98
In silico evaluation of lattice designs for additively manufactured total hip implants	97
A general sample-weighted framework for epileptic seizure prediction	96
REDDA: Integrating multiple biological relations to heterogeneous graph neural network for drug-disease association prediction	96
IVD fibrosis and disc collapse comprehensively aggravate vertebral body disuse osteoporosis and zygapophyseal joint osteoarthritis by posteriorly shifting the load transmission pattern	95
Uniqueness of inspiratory airflow patterns in a realistic rat nasal cavity	95
Identifying fetal status with fetal heart rate: Deep learning approach based on long convolution	95
Classical Simulations on Quantum Computers: Interface-Driven Peptide Folding on Simulated Membrane Surfaces	94
MulStack: An ensemble learning prediction model of multilabel mRNA subcellular localization	94
Data-driven discovery of sparse dynamical model of cardiovascular system for model predictive control	93
Insights into potential mechanisms of asthma patients with COVID-19: A study based on the gene expression profiling of bronchoalveolar lavage fluid	93
An efficient model for extracting respiratory and blood oxygen saturation data from photoplethysmogram signals by removing motion artifacts using heuristic-aided ensemble learning model	93
Extinction and stationary distribution of a stochastic COVID-19 epidemic model with time-delay	92
AGNet: Automatic generation network for skin imaging reports	92
DE-JANet: A unified network based on dual encoder and joint attention for Alzheimer’s disease classification using multi-modal data	92
EpiTEAmDNA: Sequence feature representation via transfer learning and ensemble learning for identifying multiple DNA epigenetic modification types across species	92
Quantifying the influence of combined lung and kidney support using a cardiovascular model and sensitivity analysis-informed parameter identification	92
Detecting IDH and TERTp mutations in diffuse gliomas using 1H-MRS with attention deep-shallow networks	92
DRBpred: A sequence-based machine learning method to effectively predict DNA- and RNA-binding residues	92
The role of mechano-electric feedbacks and hemodynamic coupling in scar-related ventricular tachycardia	92
AIScholar: An OpenFaaS-enhanced cloud platform for intelligent medical data analytics	92
Pharmacophore-guided computational modeling of quinolone-ATPase conjugate inhibitors targeting DNA GyrB subunit of Staphylococcus aureus	91
Context-aggregator: An approach of loss- and class imbalance-aware aggregation in federated learning	90
Beyond accuracy: The need for explainable AI in biomedical voice technology	89
Numerical analysis of coil designs to expedite fracture healing using dielectrophoresis with S method	88
Discrepancy-based diffusion models for lesion detection in brain MRI	88
A YOLO based software for automated detection and analysis of rodent behaviour in the open field arena	87
Potential inhibitors of the main protease of SARS-CoV-2 and modulators of arachidonic acid pathway: Non-steroidal anti-inflammatory drugs against COVID-19	87
The role of the extracellular matrix in the reduction of lateral force transmission in muscle bundles: A finite element analysis	87
Artificial intelligence techniques for prediction of drug synergy in malignant diseases: Past, present, and future	87
Simulated annealing aided genetic algorithm for gene selection from microarray data	86
HOTGpred: Enhancing human O-linked threonine glycosylation prediction using integrated pretrained protein language model-based features and multi-stage feature selection approach	86
Computer models evaluating hand tremors in Parkinson's disease patients	85
Artificial vascular image generation using blood vessel texture maps	84
Visual prior-based cross-modal alignment network for radiology report generation	84
Hierarchical cumulative network for unsupervised medical image registration	84
Drug repurposing of triazoles against mucormycosis using molecular docking: A short communication	83
Prediction of protein N-terminal acetylation modification sites based on CNN-BiLSTM-attention model	83
A robust drug recall supply chain management system using hyperledger blockchain ecosystem	83
Triage and monitoring of COVID-19 patients in intensive care using unsupervised machine learning	82
MCA-net: A multi-task channel attention network for Myocardial infarction detection and location using 12-lead ECGs	82
A comprehensive analysis of single-cell RNA transcriptome reveals unique SPP1+ chondrocytes in human osteoarthritis	81
Prostate158 - An expert-annotated 3T MRI dataset and algorithm for prostate cancer detection	81
Effect of tumor heterogeneity on enhancing drug delivery to vascularized tumors using thermo-sensitive liposomes triggered by hyperthermia: A multi-scale and multi-physics computational model	81
DrugormerDTI: Drug Graphormer for drug–target interaction prediction	81
Hemodynamic alternations following stent deployment and post-dilation in a heavily calcified coronary artery: In silico and ex-vivo approaches	81
Integrating CNN and Bi-LSTM for protein succinylation sites prediction based on Natural Language Processing technique	81
Predicting lung cancer survival based on clinical data using machine learning: A review	81
Identification of lncRNA associated with the SERPINE1 gene in colorectal cancer through TGF-β pathway	80
Molecular modelling and experimental validation identified a new therapeutic inhibitor of toxoplasmosis	80
Wearable-based human flow experience recognition enhanced by transfer learning methods using emotion data	80
Analysis of domain shift in whole prostate gland, zonal and lesions segmentation and detection, using multicentric retrospective data	79
Enhanced depression detection from speech using Quantum Whale Optimization Algorithm for feature selection	79
Automatic segmentation of intraluminal thrombosis of abdominal aortic aneurysms from CT angiography using a mixed-scale-driven multiview perception network (M2Net) model	79
A review of deep learning-based information fusion techniques for multimodal medical image classification	78
Novel ensemble of optimized CNN and dynamic selection techniques for accurate Covid-19 screening using chest CT images	78
Emotion recognition in EEG signals using deep learning methods: A review	77
An improved RIME optimization algorithm for lung cancer image segmentation	77
Temporal relative transformer encoding cooperating with channel attention for EEG emotion analysis	77
An efficient image segmentation method for skin cancer imaging using improved golden jackal optimization algorithm	76
Performance of multilabel machine learning models and risk stratification schemas for predicting stroke and bleeding risk in patients with non-valvular atrial fibrillation	76
Structure-based design of promising natural products to inhibit thymidylate kinase from Monkeypox virus and validation using free energy calculations	76

Sparse Dynamic Volume TransUNet with multi-level edge fusion for brain tumor segmentation	76
A hybrid methodology for breast screening and cancer diagnosis using thermography	76
A deep learning based model using RNN-LSTM for the Detection of Schizophrenia from EEG data	75
Automated tool detection with deep learning for monitoring kinematics and eye-hand coordination in microsurgery	74
A novel hybrid ViT-LSTM model with explainable AI for brain stroke detection and classification in CT images: A case study of Rajshahi region	74
CARES: A Corpus for classification of Spanish Radiological reports	74
Integrating biocomputational techniques for Breast cancer drug discovery via the HER-2, BCRA, VEGF and ER protein targets	74
GasHisSDB: A new gastric histopathology image dataset for computer aided diagnosis of gastric cancer	73
Single-channel EEG based insomnia detection with domain adaptation	73
COVID-19 diagnosis using state-of-the-art CNN architecture features and Bayesian Optimization	73
Stack-AAgP: Computational prediction and interpretation of anti-angiogenic peptides using a meta-learning framework	73
Thyroid region prior guided attention for ultrasound segmentation of thyroid nodules	72
A transformer-based deep neural network for arrhythmia detection using continuous ECG signals	72
Identification of molecular and cellular infection response biomarkers associated with anthrax infection through comparative analysis of gene expression data	72
Exploring molecular mechanisms of diazinon toxicity in HT22 hippocampal neurons through integrated miRNA and mRNA profiling	71
A computational framework to simulate the thermochemical process during thermochemical ablation of biological tissues	71
Molecular hybridization assisted multi-technique approach for designing USP21 inhibitors to halt catalytic triad-mediated nucleophilic attack and suppress pancreatic ductal adenocarcinoma progression:	71
Torque modulation mechanism of the knee joint during balance recovery	71
Transcriptome analysis displays new molecular insights into the mechanisms of action of Mebendazole in gastric cancer cells	71
Effective fall detection and post-fall breath rate tracking using a low-cost CW Doppler radar sensor	71
Interplay of mutations, alternate mechanisms, and treatment breaks in leukaemia: Understanding and implications studied with stochastic models	70
PNMC: Four-dimensional conebeam CT reconstruction combining prior network and motion compensation	70
Smoke veil prior regularized surgical field desmoking without paired in-vivo data	70
Impact of physiological loads of arterial wall on nucleus deformation in endothelial cells: A computational study	70
Validation of fluid-structure interaction simulations of the opening phase of phantom mitral heart valves under physiologically inspired conditions	70
Characterizing patients at higher cardiovascular risk for prescribed stimulants: Learning from health records data with predictive analytics and data mining techniques	69
Ce	69
Privacy preserving distributed learning classifiers – Sequential learning with small sets of data	69
FIM: A fatigued-injured muscle model based on the sliding filament theory	69
Identification of a novel gene signature for the prognosis of sepsis	69
Atten-Nonlocal Unet: Attention and Non-local Unet for medical image segmentation	69
Repeated measures analysis for steady-state evoked potentials	68
Biochemical reaction network topology defines dose-dependent Drug–Drug interactions	68
A novel compartmental model to capture the nonlinear trend of COVID-19	68
A computational optimization study of a self-expandable transcatheter aortic valve	68
Deep learning image registration for cardiac motion estimation in adult and fetal echocardiography via a focus on anatomic plausibility and texture quality of warped image	68
The detection of mild traumatic brain injury in paediatrics using artificial neural networks	68
Automated engineered-stone silicosis screening and staging using Deep Learning with X-rays	68
Cross attention guided multi-scale feature fusion for false-positive reduction in pulmonary nodule detection	68
A simplified method for relapsing-remitting multiple sclerosis detection: Insights from resting EEG signals	68
CFD simulations of inhalation through a subject-specific human larynx – Impact of the unilateral vocal fold immobility	67
Genetic algorithm based image reconstruction applying the digital holography process with the Discrete Orthonormal Stockwell Transform technique for diagnosis of COVID-19	67
A fully-convolutional residual encoder-decoder neural network to localize breast cancer on histopathology images	67
A novel mTOR-associated gene signature for predicting prognosis and evaluating tumor immune microenvironment in lung adenocarcinoma	66
Three-dimensional morphology scoring of hepatocellular carcinoma stratifies prognosis and immune infiltration	66
Computationally efficient model to predict the deformations of a cellular foot orthotic	66
Estimation of potassium levels in hemodialysis patients by T wave nonlinear dynamics and morphology markers	66
Dynamic modeling of antibody repertoire reshaping in response to viral infections	65
SWTRU: Star-shaped Window Transformer Reinforced U-Net for medical image segmentation	65
Attention2Minority: A salient instance inference-based multiple instance learning for classifying small lesions in whole slide images	65
Collaborative networks of transformers and convolutional neural networks are powerful and versatile learners for accurate 3D medical image segmentation	65
Role of [18F]-PSMA-1007 PET radiomics for seminal vesicle invasion prediction in primary prostate cancer	65
Design and hierarchical analysis of magnetic actuated robot: A governing equation based approach	64
Integrating local and global attention mechanisms for enhanced oral cancer detection and explainability	64
A multi-granularity convolutional neural network model with temporal information and attention mechanism for efficient diabetes medical cost prediction	63
Joint cardiac tissue conductivity and activation time estimation using confirmatory factor analysis	63
ACP-MLC: A two-level prediction engine for identification of anticancer peptides and multi-label classification of their functional types	63
DNA protein binding recognition based on lifelong learning	62
Editorial Board	62
SPMLD: A skin pathological image dataset for non-melanoma with detailed lesion area annotation	62
Deep learning based classification of multi-label chest X-ray images via dual-weighted metric loss	62
Cancer-inspired genomics mapper model for the generation of synthetic DNA sequences with desired genomics signatures	62
Designing a bioadjuvant candidate vaccine targeting infectious bursal disease virus (IBDV) using viral VP2 fusion and chicken IL-2 antigenic epitope: A bioinformatics approach	62
Bone marrow sparing oriented multi-model image registration in cervical cancer radiotherapy	62
A novel virtual robotic platform for controlling six degrees of freedom assistive devices with body-machine interfaces	61
Prediction of drug-target interactions via neural tangent kernel extraction feature matrix factorization model	61
A wrapper method for finding optimal subset of multimodal Magnetic Resonance Imaging sequences for ischemic stroke lesion segmentation	61
Evaluation of Cellpose segmentation with sequential thresholding for instance segmentation of cytoplasms within autofluorescence images	61
Enclosing 95% confidence area and volume to center of pressure and center of mass in posturography using optimization algorithm and coordinate ascent methods	61
Metagenome comparison (MC): A new framework for detecting unique/enriched OMUs (operational metagenomic units) derived from whole-genome sequencing reads	60
Characterization of cancer subtypes associated with clinical outcomes by multi-omics integrative clustering	60
A mathematical model of tissue axial and radial diffusion in the microvasculature for intravascular microscopy and phosphorescence quenching data	59
recruIT: A cloud-native clinical trial recruitment support system based on Health Level 7 Fast Healthcare Interoperability Resources (HL7 FHIR) and the Observational Medical Outcomes Partnership Commo	59
MOSDNET: A multi-omics classification framework using simplified multi-view deep discriminant representation learning and dynamic edge GCN with multi-task learning	59
Extensive T1-weighted MRI preprocessing improves generalizability of deep brain age prediction models	59
Classifying alkaliphilic proteins using embeddings from protein language model	58
Artificial intelligence derived categorizations significantly improve HOMA IR/β indicators: Combating diabetes through cross-interacting drugs	58
An unsupervised image registration method employing chest computed tomography images and deep neural networks	58
Wearable multisource quantitative gait analysis of Parkinson's diseases	58
An efficient cardiovascular disease prediction model through AI-driven IoT technology	58
Alcohol patch test with hue-saturation-value model analysis predicts ALDH2 genetic polymorphism	58
Structural and functional analysis of disease-associated mutations in GOT1 gene: An in silico study	57
QMaxViT-Unet+: A query-based MaxViT-Unet with edge enhancement for scribble-supervised segmentation of medical images	57
A bidirectional registration neural network for cardiac motion tracking using cine MRI images	56
Two-stage data augmentation for improved ASR performance for dysarthric speech	56
Multilevel threshold image segmentation for COVID-19 chest radiography: A framework using horizontal and vertical multiverse optimization	56
Computational identification of repurposed drugs against viruses causing epidemics and pandemics via drug-target network analysis	56
Directed Graph Mapping exceeds Phase Mapping for the detection of simulated 2D meandering rotors in fibrotic tissue with added noise	56
Automatic segmentation and classification of Papanicolaou-stained cells and dataset for oral cancer detection	56
Impact of workflow variability on image-based intracranial aneurysm hemodynamics	55
Breast cancer detection and classification: A study on the specification and implementation of multilayer perceptron analog artificial neural networks	55
SEPO-FI: Deep-learning based software to calculate fusion index of muscle cells	55
Novel classification of brain vascular tortuosity measures: A systematic review	55
Enhanced breast mass segmentation in mammograms using a hybrid transformer UNet model	55
An adaptive language model-based intelligent medication assistant for the decision support of antidepressant prescriptions	55