Drugs

Papers
(The median citation count of Drugs is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Asthma and Cardiovascular Diseases: Navigating Mutual Pharmacological Interferences490
Teclistamab: First Approval465
Senaparib: First Approval276
Targeting DNA Damage Response Deficiency in Thoracic Cancers247
Spesolimab for the Treatment of Generalized Pustular Psoriasis242
Correction: New Pharmacologic Approaches to the Treatment of Bipolar Depression219
Correction: Targeting KRASG12C in Non-Small-Cell Lung Cancer: Current Standards and Developments191
Comment on “Recent Human Papillomavirus Vaccination is Associated with a Lower Risk of COVID-19: A US Database Cohort Study”165
Eftrenonacog Alfa: A Review in Haemophilia B161
Acknowledgement to Referees155
Suprachoroidal Space Triamcinolone Acetonide: A Review in Uveitic Macular Edema146
Analysis of Cerebrospinal Fluid, Plasma β-Amyloid Biomarkers, and Cognition from a 2-Year Phase 2 Trial Evaluating Oral ALZ-801/Valiltramiprosate in APOE4 Carriers with Early Alzheimer’s Disease Using143
Epcoritamab: First Approval140
Alcohol-Associated Liver Disease: Evolving Concepts and Treatments138
Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEε4/ε4 Homozygotes with Early Alzheimer’s Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled,138
Vorasidenib: First Approval124
New Therapies on the Horizon for Primary Biliary Cholangitis123
Authors’ Reply to Toda: Multimodal Multidisciplinary Management of Patients with Moderate to Severe Pain in Knee Osteoarthritis: A Need to Meet Patient Expectations122
Aprocitentan: First Approval109
Aztreonam-Avibactam: A Review in the Treatment of Serious Bacterial Infections Caused by Aerobic Gram-Negative Organisms103
Efficacy and Safety of Plecanatide in Chinese Patients with Functional Constipation: A Phase III Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial102
Repotrectinib: First Approval100
Ivarmacitinib Sulfate: First Approval99
Acoltremon: First Approval98
Cosibelimab: First Approval92
Influenza Vaccine Effectiveness and Progress Towards a Universal Influenza Vaccine91
Olipudase Alfa: First Approval89
QT Prolongation and Risk of Death with the Use of Methadone for Chronic Cancer and Noncancer Pain: Myths or Reality?88
Danicopan: First Approval87
Tolebrutinib: First Approval86
Advances in Pharmacotherapy for Menopausal Vasomotor Symptoms84
Efficacy and Safety of CDK4/6 Inhibitors: A Focus on HR+/HER2− Early Breast Cancer83
Drugs in Development to Manage Acute Pain81
Emerging Therapies for Chronic Hepatitis B and the Potential for a Functional Cure80
Safety of Anti-osteoarthritis Medications: A Systematic Literature Review of Post-marketing Surveillance Studies79
Lenacapavir: First Approval77
Efficacy and Harms of Opioid Analgesics for Acute Pain: Overview of Systematic Reviews and Meta-analyses77
Androgenetic Alopecia: Therapy Update75
Novel Drugs for the Treatment of Pulmonary Arterial Hypertension: Where Are We Going?75
SER-109 (VOWST™): A Review in the Prevention of Recurrent Clostridioides difficile Infection72
Cancer Pain Treatment Strategies in Patients with Cancer68
Relugolix/Estradiol/Norethisterone (Norethindrone) Acetate: A Review in Symptomatic Uterine Fibroids67
Delgocitinib 20 mg/g Cream: A Review in Chronic Hand Eczema65
Sibeprenlimab: First Approval65
Treatment of Cryptococcal Meningitis: How Have We Got Here and Where are We Going?64
Alzheimer’s Disease: Novel Targets and Investigational Drugs for Disease Modification64
Mosunetuzumab: First Approval64
Mazdutide: First Approval63
Taletrectinib: First Approval63
Situational Prevention of Migraine Attacks: Can Early Treatment Change the Conversation?63
Tovorafenib: First Approval62
Pozelimab: First Approval60
Correction to: Fenfluramine: A Review in Dravet and Lennox-Gastaut Syndromes58
Correction to: Tapinarof Cream 1%: First Approval58
PARP Inhibition, a New Therapeutic Avenue in Patients with Prostate Cancer57
Targeting Interferon Signalling in Systemic Lupus Erythematosus: Lessons Learned57
Drugs Targeting Cough Receptors: New Therapeutic Options in Refractory or Unexplained Chronic Cough56
Targeting Inflammation in Bronchiectasis56
Aligning Large Language Models with Humans: A Comprehensive Survey of ChatGPT’s Aptitude in Pharmacology56
Managing Burning Mouth Syndrome: Current and Future Directions54
Ifupinostat: First Approval53
Dorzagliatin: First Approval53
Sunvozertinib: First Approval53
Pharmacological Treatments of Temporomandibular Disorders: A Systematic Review Including a Network Meta-Analysis53
Correction to: Prevention and Treatment of Monkeypox53
Pixavir Marboxil: First Approval51
Treatment of Ovarian Cancer Beyond PARP Inhibition: Current and Future Options48
The Place of Cannabinoids in the Treatment of Gynecological Pain47
Pan-JAK Inhibition Across Chronic Hand Eczema and Other Cutaneous Diseases: An Updated Review on Topical Delgocitinib47
Correction to: Concizumab: First Approval47
Focus on Metformin: Its Role and Safety in Pregnancy and Beyond46
The Utilization of the Accelerated Approval Pathway in Oncology: A Case Study of Pembrolizumab46
Birch Bark Extract: A Review in Epidermolysis Bullosa44
Correction: From Prospective Evaluation to Practice: Model-Informed Dose Optimization in Oncology44
Ozoralizumab: First Approval43
Targeting HER2 in Metastatic Colorectal Cancer: Current Therapies, Biomarker Refinement, and Emerging Strategies42
Gepirone Extended-Release: First Approval42
Pharmacological Management of Obesity in Pregnancy: A Review of Current and Emerging Therapies42
Effects of Oral ALZ-801/Valiltramiprosate on Plasma Biomarkers, Brain Hippocampal Volume, and Cognition: Results of 2-Year Single-Arm, Open-Label, Phase 2 Trial in APOE4 Carriers with Early Alzheimer’41
Correction to: Remdesivir: A Review in COVID-1941
Catumaxomab: First Approval41
Might It Be Appropriate to Anticipate the Use of Long-Acting Muscarinic Antagonists in Asthma?40
Paracetamol Combination Therapy for Back Pain and Osteoarthritis: A Systematic Review and Meta-Analyses40
Pharmacotherapy for Dravet Syndrome: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials40
Antiseizure Medications that Did Not Reach the Epilepsy Market: An Assessment of Factors Contributing to Their Failed Clinical Development Over the Last Three Decades40
Givinostat: First Approval39
Safety and Tolerability of Glucagon-Like Peptide-1 Receptor Agonists: A State-of-the-Art Narrative Review39
Update on Mpox Management: Epidemiology, Vaccines and Therapeutics, and Regulatory Changes39
Recent Human Papillomavirus Vaccination is Associated with a Lower Risk of COVID-19: A US Database Cohort Study39
Tirzepatide: A Review in Type 2 Diabetes39
Mitapivat: A Review in Pyruvate Kinase Deficiency in Adults39
Current Management of Peripheral Artery Disease: Focus on Pharmacotherapy39
Current and Emerging Treatments for Acid Sphingomyelinase Deficiency39
Correction: Ifupinostat: First Approval38
Ensitrelvir Fumaric Acid: First Approval38
Atrasentan: First Approval38
Correction: Teprotumumab: A Review in Thyroid Eye Disease38
Sequential Use of Trastuzumab Deruxtecan and Sacituzumab Govitecan in Patients with Breast Cancer: A Pharmacological Approach to Support the Clinical Rationale38
Fezolinetant: First Approval37
Omalizumab in Severe Asthma: Effect on Oral Corticosteroid Exposure and Remodeling. A Randomized Open-Label Parallel Study37
Becotatug Vedotin: First Approval36
Polidocanol in Sclerotherapy for Lymphovenous Disorders: Mechanisms, Clinical Uses, and Future Prospects36
Antifungal Treatment Regimens as Primary Therapy for Invasive Aspergillosis: A Systematic Review and Network Meta-analysis35
Eye Involvement and Management in Inherited Epidermolysis Bullosa35
Avacincaptad Pegol: First Approval35
Futibatinib: First Approval35
Current Understanding of Complement Proteins as Therapeutic Targets for the Treatment of Immunoglobulin A Nephropathy35
Spondyloarthropathy in Inflammatory Bowel Disease: From Pathophysiology to Pharmacological Targets34
Correction: Iptacopan: First Approval34
Advanced-Stage Chronic Myeloid Leukemia: Options for Difficult Treatment Situations34
Correction: Lumasiran: A Review in Primary Hyperoxaluria Type 134
Oral Gut-Restricted Targeted Therapy for IBD: A Pipeline Review34
Zeprumetostat: First Approval33
Tamoxifen Dose De-Escalation: An Effective Strategy for Reducing Adverse Effects?33
Effectiveness of Interventions to Reduce Opioid Use After Orthopaedic Surgery: A Systematic Review of Randomised Controlled Trials33
Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries33
Beremagene Geperpavec: First Approval33
Managing Pain in Fibromyalgia: Current and Future Options33
Imetelstat: First Approval32
Zastaprazan: First Approval32
Recent United States Developments in the Pharmacological Treatment of Dry Eye Disease32
Safety of Janus Kinase Inhibitors in Inflammatory Bowel Diseases32
Lotilaner Ophthalmic Solution 0.25%: First Approval32
Remdesivir Discontinuation Decisions Based on Thresholds of Aminotransferase in an Observational Registry31
Acknowledgement to Referees31
Varenicline Solution Nasal Spray: A Review in Dry Eye Disease31
Targeting the Sphingosine-1-Phosphate Pathway: New Opportunities in Inflammatory Bowel Disease Management30
Mavorixafor: First Approval30
Diagnosis and Treatment of AL Amyloidosis29
Retifanlimab: First Approval29
Nogapendekin alfa Inbakicept: First Approval29
Sepiapterin: First Approval29
Revumenib: First Approval29
Crinecerfont: First Approval29
Botulinum Toxin-A for the Treatment of Myogenous Temporomandibular Disorders: An Umbrella Review of Systematic Reviews29
Revolutionary Changes in the Management of Lupus Nephritis: Towards De-Glucocorticoid or No-Glucocorticoid28
Gabapentinoids for Pain: A Review of Published Comparative Effectiveness Trials and Data Submitted to the FDA for Approval28
Efficiency and Safety of Noninvasive and Intravesical Therapy for Adult Neurogenic Lower Urinary Tract Dysfunction: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials28
Direct-Acting Antivirals and the Risk of Arrhythmias and Conduction Disorders in Patients with Chronic Hepatitis C: A French Nationwide Cohort Study28
Immune Mechanisms in Epileptogenesis: Update on Diagnosis and Treatment of Autoimmune Epilepsy Syndromes28
Antibacterials with Novel Chemical Scaffolds in Clinical Development27
Correction to: Sparsentan: First Approval27
Zolbetuximab: First Approval27
Methadone for Cancer Pain Management in Children: A Review of Literature27
Onradivir: First Approval27
Correction: Zastaprazan: First Approval27
Remdesivir: A Review in COVID-1927
Correction to: Spesolimab: First Approval27
Comment on: “Risk of Erectile Dysfunction in Male Patients with Gout Treated with Febuxostat or Allopurinol: A Propensity Score-Matched Cohort Study”27
Tradipitant: First Approval27
Moderate-Intensity Statin Plus Ezetimibe: Time to Rethink it as an Optimal Initial Lipid-Lowering Strategy26
Ravulizumab: A Review in Generalised Myasthenia Gravis26
Efficacy and Safety of Sovateltide in Patients with Acute Cerebral Ischaemic Stroke: A Randomised, Double-Blind, Placebo-Controlled, Multicentre, Phase III Clinical Trial26
Keverprazan Hydrochloride: First Approval26
Combination of PARP Inhibitors and Androgen Receptor Pathway Inhibitors in Metastatic Castration-Resistant Prostate Cancer26
Ripretinib: A Review in Gastrointestinal Stromal Tumours as Fourth-or Later-Line of Therapy25
Marstacimab: First Approval25
Publisher Correction: Efficacy and Safety of RBX2660 in PUNCH CD3, a Phase III, Randomized, Double-Blind, Placebo-Controlled Trial with a Bayesian Primary Analysis for the Prevention of Recurrent Clos25
Elranatamab: First Approval25
Novel Drug Therapeutics in Celiac Disease: A Pipeline Review25
Spesolimab: First Approval24
Current and Future Pharmacological Interventions for Acquired Hypothalamic Obesity24
Refractory Systemic Lupus Erythematosus: Identification and Pharmacological Management24
A Review of RRx-001: A Late-Stage Multi-Indication Inhibitor of NLRP3 Activation and Chronic Inflammation24
Lecanemab: First Approval24
Nadofaragene Firadenovec: First Approval24
Treatment of Osteoporosis and Osteoarthritis in the Oldest Old24
Tixagevimab + Cilgavimab: First Approval24
Correction to: Rozanolixizumab: First Approval23
Ritlecitinib: First Approval23
Ziftomenib: First Approval23
Zongertinib: First Approval23
Renal Safety Assessment of Lipid-Lowering Drugs: Between Old Certainties and New Questions23
Correction to: Mavacamten: First Approval23
Amubarvimab/Romlusevimab: First Approval23
Comment on: ‘Should We Interfere with the Interleukin-6 Receptor During COVID-19: What Do We Know?’22
Tofersen: First Approval22
Risk of COVID-19 Diagnosis and Hospitalisation in Patients with Osteoarthritis or Back Pain Treated with Ibuprofen Compared to Other NSAIDs or Paracetamol: A Network Cohort Study22
Pucotenlimab: First Approval22
Targeted Small Molecules for Systemic Lupus Erythematosus: Drugs in the Pipeline22
Comment on “Trientine Tetrahydrochloride, From Bench to Bedside: A Narrative Review”22
Paltusotine: First Approval22
Correction to: Ozanimod: A Review in Ulcerative Colitis21
Benefits and Liabilities of Benzodiazepines and Z-Drugs: What We Know and What We Don’t Know21
Pharmacological Therapies in Paroxysmal Nocturnal Haemoglobinuria: Focus on Complement Inhibition21
Elafibranor: First Approval21
New Developments in Glucagon Treatment for Hypoglycemia21
Trastuzumab Rezetecan: First Approval20
Drug Survival of IL-17 and IL-23 Inhibitors for Psoriasis: A Systematic Review and Meta-Analysis20
Association of Glucagon-Like Peptide-1 Receptor Agonist with Progression to Liver Cirrhosis and Alcohol-Related Admissions in Patients with Alcohol Use Disorder and Diabetes: A Retrospective Cohort St20
Chronic Obstructive Pulmonary Disease (COPD): Developments in Pharmacological Treatments20
Gepotidacin: First Approval20
Valoctocogene Roxaparvovec: First Approval20
Talquetamab: First Approval20
Correction: Senaparib: First Approval20
Differentiating IL-23 Inhibitors in Crohn’s Disease20
Sirtuins and Cellular Senescence in Patients with Idiopathic Pulmonary Fibrosis and Systemic Autoimmune Disorders20
Eplontersen: First Approval20
A Meta-analysis Exploring the Efficacy of Neuropathic Pain Medication for Low Back Pain or Spine-Related Leg Pain: Is Efficacy Dependent on the Presence of Neuropathic Pain?20
Treatment Approaches for Carbapenem-Resistant Acinetobacter baumannii Infections19
Tirzepatide: First Approval19
TKI Treatment Sequencing in Advanced Gastrointestinal Stromal Tumors19
Sipavibart: First Approval19
PI3K Inhibitors as Potential Therapeutic Agents for the Treatment of COPD with Associated Atherosclerosis19
Minimal Residual Disease Negativity as the Primary Goal of Multiple Myeloma Therapy18
PCSK9 Inhibitors: A Potential Priority Choice for Lipid Management in Patients with Diabetic Kidney Disease18
Mirvetuximab Soravtansine: First Approval18
Ensifentrine Plus a Long-Acting Muscarinic Antagonist in COPD: A Trifunctional Dual Bronchodilation Perspective18
Iptacopan: First Approval18
Dimdazenil: First Approval18
Tunlametinib: First Approval18
Motixafortide: First Approval18
20-Valent Pneumococcal Conjugate Vaccine: A Review of Its Use in Adults18
Intraperitoneal Chemotherapy for Unresectable Peritoneal Surface Malignancies18
Pharmacological, Natural and Emerging Therapies for Meibomian Gland Dysfunction: A Review18
How Psychedelics Modulate Multiple Memory Mechanisms in Posttraumatic Stress Disorder18
Vutrisiran: A Review in Polyneuropathy of Hereditary Transthyretin-Mediated Amyloidosis17
Treatment Options in Spinal Muscular Atrophy: A Pragmatic Approach for Clinicians17
Sulbactam/Durlobactam: First Approval17
Nemolizumab: First Approval17
Vimseltinib: First Approval17
Overall and Sex-Specific Effect of Berberine for the Treatment of Dyslipidemia in Adults: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials17
Drugs in Development to Treat IgA Nephropathy17
Linzagolix: First Approval17
Cabotegravir Extended-Release Injectable Suspension: A Review in HIV-1 Pre-Exposure Prophylaxis17
Exploring Novel Pharmacotherapy Candidates for Cannabis Use Disorder: Uncovering Promising Agents on the Horizon by Mechanism of Action17
Use of Levosimendan in Patients with Pulmonary Hypertension: What is the Current Evidence?17
Biased Kappa-opioid Agonist Strategies in Pain Management: Approaches to Clinical Benefits with Reduced Adverse Effects17
Clesrovimab: First Approval17
Drug-Induced Pigmentation: A Review17
Vamorolone: First Approval17
Results from Expanded Access Programs: A Review of Academic Literature17
Tegileridine: First Approval17
Chinese Herbal Medicines for Coronary Heart Disease: Clinical Evidence, Pharmacological Mechanisms, and the Interaction with Gut Microbiota17
Postpartum Depression: A Clinical Review of Impact and Current Treatment Solutions17
Fitusiran: First Approval16
Ebronucimab: First Approval16
The Struggle to End a Millennia-Long Pandemic: Novel Candidate and Repurposed Drugs for the Treatment of Tuberculosis16
Systemic Therapy for Advanced Thyroid Cancer—New Personalized Options16
Rezvilutamide: First Approval16
Pharmacological Management of Hypertrophic Cardiomyopathy: From Bench to Bedside16
In Search of the Optimal Antithrombotic Regimen for Intracerebral Hemorrhage Survivors with Atrial Fibrillation16
Weight Loss Versus Glycemic Control as the Primary Treatment Target in Newly Diagnosed Type 2 Diabetes: Why Choose When You Can Have Both?16
Extended and Continuous Infusion of Novel Protected β-Lactam Antibiotics: A Narrative Review15
Oteseconazole: First Approval15
Managing Psoriatic Arthritis Patients Presenting with Axial Symptoms15
Famitinib: First Approval15
Fenfluramine: A Review in Dravet and Lennox-Gastaut Syndromes15
Pirtobrutinib: First Approval15
Vonoprazan: A Review in Helicobacter pylori Infection15
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