OOIR: Observatory of International Research

Papers

(The median citation count of Endocrinology is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
A Causal Link Between Disrupted AKT Signaling and Hyperproliferative Endometrial Diseases	105
Cholesterol Deprivation Drives DHEA Biosynthesis in Human Adrenals	89
Reformulation of PULSAR for Analysis of Pulsatile LH Secretion and a Revised Model of Estrogen-Negative Feedback in Mice	85
Adipose-specific VDR Deletion Leads to Hepatic Steatosis in Female Mice Fed a Low-Fat Diet	85
Deletion of Gdf15 Reduces ER Stress-induced Beta-cell Apoptosis and Diabetes	58
Corrigendum to: “Role of Ovarian Hormones in the Modulation of Sleep in Females Across the Adult Lifespan”	54
The Lack of Bmal1, a Core Clock Gene, in the Intestine Decreases Glucose Absorption in Mice	50
Experimentally Induced Hyperglycemia in Prepubertal Phase Impairs Oocyte Quality and Functionality in Adult Mice	49
Paracrine Regulation of Adipose Tissue Macrophages by Their Neighbors in the Microenvironment of Obese Adipose Tissue	45
Steroidogenic Factor 1 Regulation of the Hypothalamic-Pituitary-Ovarian Axis of Adult Female Mice	45
Simulation Model for Hashimoto Autoimmune Thyroiditis Disease	41
Insulin Signaling Via Retinal Pericytes, New Insights and Potential Implications in Diabetic Retinopathy	39
Beta-Hydroxybutyrate Suppresses Hepatic Production of the Ghrelin Receptor Antagonist LEAP2	39
Maternal Hypothyroidism in Rats Reduces Placental Lactogen, Lowers Insulin Levels, and Causes Glucose Intolerance	36
C-type Natriuretic Peptide–induced PKA Activation Promotes Endochondral Bone Formation in Hypertrophic Chondrocytes	33
Transient Dexamethasone Loading Induces Prolonged Hyperglycemia in Male Mice With Histone Acetylation in Dpp-4 Promoter	32
Wnt5a Regulates Junctional Function of Sertoli cells Through PCP-mediated Effects on mTORC1 and mTORC2	31
Maternal Thyroid Function and Birth Weight in Twins	31
Functional Lactotrophs in Induced Adenohypophysis Differentiated From Human iPS Cells	29
Jumonji Domain–containing Protein-3 (JMJD3/Kdm6b) Is Critical for Normal Ovarian Function and Female Fertility	28
Population Numbers and Reproductive Health	28
Erratum to: “Endoxifen, an Estrogen Receptor Targeted Therapy: from Bench to Bedside”	27
O-GlcNAcylation Is Essential for RapidPomcExpression and Cell Proliferation in Corticotropic Tumor Cells	25
Regulation of AKT Signaling in Mouse Uterus	24
Inflammasome Activation and Pyroptosis via a Lipid-regulated SIRT1-p53-ASC Axis in Macrophages From Male Mice and Humans	24

Insulin Null β-cells Have a Prohormone Processing Defect That Is Not Reversed by AAV Rescue of Proinsulin Expression	24
Small Molecule-mediated Insulin Hypersecretion Induces Transient ER Stress Response and Loss of Beta Cell Function	24
PGE2 and Thrombin Induce Myofibroblast Transdifferentiation via Activin A and CTGF in Endometrial Stromal Cells	24
Enterocyte HKDC1 Modulates Intestinal Glucose Absorption in Male Mice Fed a High-fat Diet	24
Inhibin Inactivation in Female Mice Leads to Elevated FSH Levels, Ovarian Overstimulation, and Pregnancy Loss	24
Distinctions in PCOS Induced by Letrozole Vs Dehydroepiandrosterone With High-fat Diet in Mouse Model	24
The Role of Mitochondria-Linked Fatty-Acid Uptake-Driven Adipogenesis in Graves Orbitopathy	23
Ablation of Growth Hormone Receptor in GABAergic Neurons Leads to Increased Pulsatile Growth Hormone Secretion	23
The Modulatory Role of Growth Hormone in Inflammation and Macrophage Activation	22
The Intersection of Cellular and Systemic Metabolism: Metabolic Syndrome in Systemic Lupus Erythematosus	22
FOXO Transcription Factors Are Required for Normal Somatotrope Function and Growth	22
Placental sFlt-1 Gene Delivery in Early Primate Pregnancy Suppresses Uterine Spiral Artery Remodeling	21
Correction to: Nuclear Progestin Receptor Mediated Linkage of Blood Coagulation and Ovulation	21
Vasoinhibin is Generated and Promotes Inflammation in Mild Antigen-induced Arthritis	21
Crosstalk Between Adipose and Lymphatics in Health and Disease	20
IGSF1 Deficiency Leads to Reduced TSH Production Independent of Alterations in Thyroid Hormone Action in Male Mice	20
Correction to: Hormonally Regulated Myogenic miR-486 Influences Sex-specific Differences in Cancer-induced Skeletal Muscle Defects	20
Corrigendum to: The Phytoestrogen Coumestrol is a Naturally Occurring Antagonist of the Human Pregnane X Receptor	20
Uterine Epithelial LIF Receptors Contribute to Implantation Chamber Formation in Blastocyst Attachment	19
Adrenal Corticosteroid Perturbation by the Endocrine Disruptor BDE-47 in a Human Adrenocortical Cell Line and Male Rats	19
The Estrogen Receptor α Cistrome in Human Endometrium and Epithelial Organoids	19
LH Induces De Novo Cholesterol Biosynthesis via SREBP Activation in Granulosa Cells During Ovulation in Female Mice	19
The β-Hydroxybutyrate-GPR109A Receptor Regulates Fasting-induced Plasticity in the Mouse Adrenal Medulla	19
A Protective Role for Glucagon-like Peptide-2 in Heat-stable Enterotoxin b (STb)-Induced L-Cell Toxicity	18
Long-term Hyperandrogenemia and/or Western-style Diet in Rhesus Macaque Females Impairs Preimplantation Embryogenesis	18
Recognition of Reviewers	17
Follicular Hyperstimulation Dysgenesis: New Explanation for Adverse Effects of Excessive FSH in Ovarian Stimulation	17
Expression Profile of the GLP-1 Receptor in the Gastrointestinal Tract and Pancreas in Adult Female Mice	17
CUX2/KDM5B/SOX17 Axis Affects the Occurrence and Development of Breast Cancer	17
Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse	16
Oocyte Quiescence: From Formation to Awakening	16
Breast Cancer Endocrine Therapy Promotes Weight Gain With Distinct Adipose Tissue Effects in Lean and Obese Female Mice	16
Novel Pathogenic De Novo INS p.T97P Variant Presenting With Severe Neonatal DKA	16
Hsa_circ_0023990 Promotes Tumor Growth and Glycolysis in Dedifferentiated TC via Targeting miR-485-5p/FOXM1 Axis	16
Knockdown of Acid-sensing Ion Channel 1a in the PVN Promotes Metabolic Disturbances in Male Mice	16
Estrogen and Progesterone Therapy and Meningiomas	16
Deficiency of C1QL1 Reduced Murine Ovarian Follicle Reserve Through Intraovarian and Endocrine Control	15
Differential Effects of Viral Nucleic Acid Sensor Signaling Pathways on Testicular Sertoli and Leydig Cells	15
The G209R mutant mouse as a model for human PCSK1 polyendocrinopathy	15
Human Population Density and Reproductive Health: A Changing World Needs Endocrinology	15
Co-existing Neuropeptide FF and Gonadotropin-Releasing Hormone 3 Coordinately Modulate Male Sexual Behavior	15
Maternal Iron Deficiency Alters Trophoblast Differentiation and Placental Development in Rat Pregnancy	15
Multisensory Stimulation Improves Cognition and Behavior in Adult Male Rats Born to LT4-treated Thyroidectomized Dams	14
Circadian Rhythms in the Neuronal Network Timing the Luteinizing Hormone Surge	14
Chronic Estrus Disrupts Uterine Gland Development and Homeostasis	14
Somatostatin Receptor Antagonism Reverses Glucagon Counterregulatory Failure in Recurrently Hypoglycemic Male Rats	14
Disruption of Growth Hormone Receptor in Adipocytes Improves Insulin Sensitivity and Lifespan in Mice	14
Liver Sex Dimorphism and Zonation Shaped by Growth Hormone	13
Pericyte Insulin Receptors Modulate Retinal Vascular Remodeling and Endothelial Angiopoietin Signaling	13
Vasoactive Intestinal Peptide Indirectly Elicits Pituitary LH Secretion Independent of GnRH in Female Zebrafish	13

Unexplored Functions of Sex Hormones in Glioblastoma Cancer Stem Cells	13
Is E2F1 a Potential Medical Therapy Target for Cushing Disease?	13
In Vivo Photometry Reveals Insulin and 2-Deoxyglucose Maintain Prolonged Inhibition of VMH Vglut2 Neurons in Male Mice	13
Epigenetic Modifications Guide Maturational Processes in Rat Pancreatic Islets	13
Noncanonical Wnt Signaling in the Integrity of the Blood-Testis Barrier and Sperm Release	12
Corticotropin-Releasing Factor Aggravates Ischemic Stroke Injury by the Inflammatory Activation of Microglia	12
Acute Deletion of the FOXO1-dependent Hepatokine FGF21 Does not Alter Basal Glucose Homeostasis or Lipolysis in Mice	12
Interferon Signaling in Estrogen Receptor–positive Breast Cancer: A Revitalized Topic	12
Nuclear Progestin Receptor–mediated Linkage of Blood Coagulation and Ovulation	12
Developmental Programming: Prenatal Testosterone Excess on Liver and Muscle Coding and Noncoding RNA in Female Sheep	12
Intestinal Epithelial NAD+ Biosynthesis Regulates GLP-1 Production and Postprandial Glucose Metabolism in Mice	12
Ductal Carcinoma In Situ of Breast: From Molecular Etiology to Therapeutic Management	12
Metabolic Homeostasis: It’s All in the Timing	12
Mechanisms of OCT4 on 3,5,3’-Tri-iodothyronine and FSH-induced Granulosa Cell Development in Female Mice	11
Identification of Novel Regulatory Regions Induced by Intrauterine Growth Restriction in Rat Islets	11
Sex Differences in Embryonic Gonad Transcriptomes and Benzo[a]pyrene Metabolite Levels After Transplacental Exposure	11
Adipose Mitochondrial Complex I Deficiency Modulates Inflammation and Glucose Homeostasis in a Sex-Dependent Manner	11
Calcitonin Gene Related Peptide, Adrenomedullin, and Adrenomedullin 2 Function in Uterine Artery During Human Pregnancy	11
Long Noncoding RNA MIAT Modulates the Extracellular Matrix Deposition in Leiomyomas by Sponging MiR-29 Family	11
Androgen-mediated Perturbation of the Hepatic Circadian System Through Epigenetic Modulation Promotes NAFLD in PCOS Mice	11
Growth Hormone-induced STAT5B RegulatesStarGene Expression Through a Cooperation With cJUN in Mouse MA-10 Leydig Cells	11
Open Chromatin State of Dpp4 With Glucocorticoid Treatment—Setting up Shop for Metasteroid Diabetes?	11
The Role of JMJD3 in Ovarian Follicular Development	11
HIV-1 Establishes a Sanctuary Site in the Testis by Permeating the BTB Through Changes in Cytoskeletal Organization	10
Sex and Gender Differences in Anticancer Treatment Toxicity: A Call for Revisiting Drug Dosing in Oncology	10
Conversion of Classical and 11-Oxygenated Androgens by Insulin-Induced AKR1C3 in a Model of Human PCOS Adipocytes	10
Targeting mTOR in the Context of Diet and Whole-body Metabolism	10
Reassessment of the Proteomic Composition and Function of Extracellular Vesicles in the Seminal Plasma	10
Regulatory T Cell Proportion and Phenotype Are Altered in Women Using Oral Contraception	10
The Pancreatic ß-cell Response to Secretory Demands and Adaption to Stress	10
Mitotane Targets Lipid Droplets to Induce Lipolysis in Adrenocortical Carcinoma	10
Erratum to: “ABCD of Thyroid Hormone Action: After and Before Cloning of Deiodinase Genes”	10
N/C Interactions Are Dispensable for Normal In Vivo Functioning of the Androgen Receptor in Male Mice	10
Sex-specific Effects of Endocrine-disrupting Chemicals on Brain Monoamines and Cognitive Behavior	10
Corrigendum to: Adiponectin Inhibits Lipopolysaccharide-Induced Adventitial Fibroblast Migration and Transition to Myofibroblasts via AdipoR1-AMPK-iNOS Pathway	10
PCP Protein Inversin Regulates Testis Function Through Changes in Cytoskeletal Organization of Actin and Microtubules	10
Effects of the Isolated and Combined Ablation of Growth Hormone and IGF-1 Receptors in Somatostatin Neurons	10
GDF15 in Appetite and Exercise: Essential Player or Coincidental Bystander?	10
Hypothalamic Expression of Estrogen Receptor Isoforms Underlies Estradiol Control of Luteinizing Hormone in Female Rats	10
Corrigendum to: Thrombin Cleaves Prolactin Into a Potent 5.6-kDa Vasoinhibin: Implication for Tissue Repair	10
Scream Sound-induced Chronic Psychological Stress Results in Diminished Ovarian Reserve in Adult Female Rat	9
MiR-205-5p/GGCT Attenuates Growth and Metastasis of Papillary Thyroid Cancer by Regulating CD44	9
The Multifaceted Melanocortin Receptors	9
Deletion of PTP1B From Brain Neurons Partly Protects Mice From Diet-Induced Obesity and Minimally Improves Fertility	9
Osteoblast Lineage Cell-derived Sema3A Regulates Bone Homeostasis Independently of Androgens	9
Impact of COVID-19 on the Endocrine System: A Mini-review	9
Disrupted and Elevated Circadian Secretion of Glucagon-Like Peptide-1 in a Murine Model of Type 2 Diabetes	9
Hormonal Crosstalk Between Thyroid and Breast Cancer	9
Deletion of Gαq/11 or Gαs Proteins in Gonadotropes Differentially Affects Gonadotropin Production and Secretion in Mice	9
Al-MPS Obstructs EMT in Breast Cancer by Inhibiting Lipid Metabolism via miR-215-5p/SREBP1	9
Loss of Hepatic Small Heterodimer Partner Elevates Ileal Bile Acids and Alters Cell Cycle-related Genes in Male Mice	9