Epilepsia

Article	Citations
Statistical learning in epilepsy: Behavioral and anatomical mechanisms in the human brain	483
Psychological precursors of epileptic seizures	473
The value of additional electrodes when stereo‐electroencephalography is inconclusive	257
Identification of drug resistance in a validated cohort of incident epilepsy patients in the Danish National Patient Register	210
Epilepsia – June 2021 – Announcements	203
Epilepsia – August 2022 – Announcements	153
Clinical and imaging features of nonmotor onset seizure in poststroke epilepsy	148
Nonconvulsive status epilepticus in patients under intensive care: Should we view epilepsy as a sleep disorder?	127
Valproate discontinuation in girls and women of childbearing age with epilepsy: An Italian multicenter retrospective study on prescribing patterns and outcomes	123
Cytomegalic parvalbumin neurons in fetal cases of hemimegalencephaly	94
Ablation of apparent diffusion coefficient hyperintensity clusters in mesial temporal lobe epilepsy improves seizure outcomes after laser interstitial thermal therapy	89
Portable ultra‐low‐field magnetic resonance imaging enables postictal seizure imaging	89
Generic lamotrigine extended‐release tablets are bioequivalent to innovator drug in fully replicated crossover bioequivalence study	80
Correction to “Imbalance between hippocampal projection cell and parvalbumin interneuron architecture increases epileptic susceptibility in mouse model of methyl CpG binding protein 2 dupli	79
Equity in access to antiseizure medications: Who has the right to decide and what are the consequences of crisis decisions?	78
Imbalance between hippocampal projection cell and parvalbumin interneuron architecture increases epileptic susceptibility in mouse model of methyl CpG binding protein 2 duplication syndrome	78
Global modified‐Delphi consensus on comorbidities and prognosis of SCN8A‐related epilepsy and/or neurodevelopmental disorders	75
Factors associated with long‐term outcomes in pediatric refractory status epilepticus	73
Pharmacological inhibition of STriatal‐Enriched protein tyrosine Phosphatase by TC‐2153 reduces hippocampal excitability and seizure propensity	72
Passive and active markers of cortical excitability in epilepsy	72
Novel lissencephaly‐associated DCX variants in the C‐terminal DCX domain affect microtubule binding and dynamics	68
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Quantifying and controlling the impact of regression to the mean on randomized controlled trials in epilepsy	62
Issue Information	62

Does the ketogenic ratio matter when using ketogenic diet therapy in pediatric epilepsy?	60
Traumatic brain injury, stroke, and epilepsy: A mediation study in a Danish nationwide cohort	58
Hemispherotomy in children: A retrospective analysis of 152 surgeries at a single center and predictors for long‐term seizure outcome	56
Acute symptomatic seizures secondary to myelin oligodendrocyte glycoprotein antibody‐associated disease	56
Transcranial magnetic stimulation in progressive myoclonus epilepsy: A promising tool for “deep phenotyping” in genetic epilepsies	54
Seizure‐free days as a novel outcome in patients with Lennox–Gastaut syndrome: Post hoc analysis of patients receiving cannabidiol in two randomized controlled trials	53
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Epilepsia—February 2023—Announcements	53
Postoperative progression of brain metastasis is associated with seizures	53
Periventricular nodular heterotopia associated with a “transmantle band sign” in patients with epilepsy	53
Dorsal bed nucleus of stria terminalis in depressed and nondepressed temporal lobe epilepsy patients	53
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Recognition and epileptology of protracted CLN3 disease	50
Plasma metabolome reveals altered oxidative stress, inflammation, and amino acid metabolism in dogs with idiopathic epilepsy	49
Bone development in offspring of pregnant rats treated with carbamazepine: Evaluation by three different methods	47
Issue Information	47
Febrile seizures lead to prolonged epileptiform activity and hyperoxia that when blocked prevents learning deficits	45
Changes in local and network brain activity after stereotactic thermocoagulation in patients with drug‐resistant epilepsy	44
Neural recruitment by ephaptic coupling in epilepsy	44
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Prophecy or empiricism? Clinical value of predicting versus determining genetic variant functions	44
The changing landscape of electrical stimulation language mapping with subdural electrodes and stereoelectroencephalography for pediatric epilepsy: A literature review and commentary	44
Issue Information	43
How accurate do self‐reported seizures need to be for effective medication management in epilepsy?	43
Changes in postictal cerebral perfusion are related to the duration of electroconvulsive therapy‐induced seizures	43
Epilepsia – March 2023 – Announcements	43
Diagnostic and therapeutic approaches in refractory insular epilepsy	43
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Thank you to our Reviewers	41
Strategic targeting of the temporal lobe with orthogonal placement of responsive neurostimulation leads	41
Hippocampal position and orientation as prognostic biomarkers for posttraumatic epileptogenesis: An experimental study in a rat lateral fluid percussion model	40
High‐dose folic acid and cancer risk; unjustified concerns by von Wrede and colleagues regarding our paper	38
Clinical presentation and evaluation of epilepsy with eyelid myoclonia: Results of an international expert consensus panel	38
Self‐esteem mediates mental health outcomes in young people with epilepsy	38
Intracerebroventricular administration for delivery of antiseizure therapeutics: Challenges and opportunities	36
Duration of epileptic seizure types: A data‐driven approach	36
Domain‐specific relationships of subjective and objective cognition in epilepsy	36
Postoperative seizure and memory outcome of temporal lobe epilepsy with hippocampal sclerosis: A systematic review	35
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Elevated Astrocytic NFAT5 of the hippocampus increases epilepsy susceptibility in hypoxic‐ischemic mice	34
Clinical utility of exome sequencing in a pediatric epilepsy cohort	33
Reasons for ineligibility for clinical trials of patients with medication‐resistant epilepsy	33
Characterizing thalamic and basal ganglia nuclei in medically intractable focal epilepsy by MR fingerprinting	32
Levetiracetam dosing in patients receiving continuous renal replacement therapy	32
Hyperperfusion Tmax mapping for nonconvulsive status epilepticus in the acute setting: A pilot case–control study	32
Issue Information	32
IRF2BPL: A new genotype for progressive myoclonus epilepsies	31
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Natural history of rare diseases using natural language processing of narrative unstructured electronic health records: The example of Dravet syndrome	31
Comment on: Failure to use new breakthrough treatments for epilepsy	31

Epilepsia – January 2024 announcements	30
Adrenal insufficiency among children treated with hormonal therapy for infantile spasms	30
From basic sciences and engineering to epileptology: A translational approach	29
Indirect structural changes and reduced controllability after temporal lobe epilepsy resection	29
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Impact of sociodemographic disadvantage on neurobehavioral outcomes in children with newly diagnosed seizures and their unaffected siblings over 36 months	29
Introduction—Special issue ICTALS 2022	29
Personalized seizure signature: An interpretable approach to false alarm reduction for long‐term epileptic seizure detection	29
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The EpiPick algorithm to select appropriate antiseizure medications in patients with epilepsy: Validation studies and updates	29
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Sustained seizure freedom with adjunctive brivaracetam in patients with focal onset seizures	28
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Issue Information	28
Can in vitro studies aid in the development and use of antiseizure therapies? A report of the ILAE/AES Joint Translational Task Force	28
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Satellite Symposia Abstracts	28
Single‐neuron correlate of epilepsy‐related cognitive deficits in visual recognition memory in right mesial temporal lobe	27
Early timing of anesthesia in status epilepticus is associated with complete recovery: A 7‐year retrospective two‐center study	27
Are we there yet? A critical evaluation of sudden and unexpected death in epilepsy models	27
Natural language processing for identification of refractory status epilepticus in children	27
The true prevalence of psychogenic nonepileptic seizures is much higher than this	27
Interictal respiratory variability predicts severity of hypoxemia after generalized convulsive seizures	27
Trajectories of parent well‐being in children with drug‐resistant epilepsy	27
Effective connectivity differs between focal cortical dysplasia types I and II	27
Why are type II focal cortical dysplasias frequently located at the bottom of sulcus? A neurodevelopmental hypothesis	27
Efficacy and safety of cannabidivarin treatment of epilepsy in girls with Rett syndrome: A phase 1 clinical trial	26
Real‐world user experience with seizure detection wearable devices in the home environment	26
Diverse genetic causes of polymicrogyria with epilepsy	26
Surgical outcome of temporal plus epilepsy is improved by multilobar resection	26
Cenobamate as add‐on treatment for SCN8A developmental and epileptic encephalopathy	26
A combination of phenobarbital and the bumetanide derivative bumepamine prevents neonatal seizures and subsequent hippocampal neurodegeneration in a rat model of birth asphyxia	26
The seasonality of new‐onset refractory status epilepticus (NORSE)	26
A novel approach to automatic seizure detection using computer vision and independent component analysis	26
Girdin deficiency causes developmental and epileptic encephalopathy with hippocampal sclerosis and interneuronopathy	25
Emergency department and inpatient interhospital transfers for patients with status epilepticus	25
Vagus nerve stimulation in Lennox–Gastaut syndrome: Twenty‐four‐month data and experience from the CORE‐VNS study	25
A review of the putative antiseizure and antiepileptogenic mechanisms of action for soticlestat	25
Stereoelectroencephalographic thermocoagulation in FLNA‐positive heterotopia: Is it an effective treatment?	24
Predictors of therapeutic response following thalamic neuromodulation for drug‐resistant pediatric epilepsy: A systematic review and individual patient data meta‐analysis	24
Population pharmacokinetics of levetiracetam in patients diagnosed with refractory epilepsy: A real‐world study	24
Exploring the impact of climate change on epilepsy: Insights from the 15th European Epilepsy Congress	24
SCN8A self‐limited infantile epilepsy: Does epilepsy resolve?	24
Evaluating the effectiveness of medical therapy in infantile epileptic spasms syndrome due to surgically‐remediable lesions	24
The Imaging Database for Epilepsy And Surgery (IDEAS)	24
Add‐on cannabidiol in patients with Dravet syndrome: Results of a long‐term open‐label extension trial	23
Seizure detection with deep neural networks for review of two‐channel electroencephalogram	23
MicroRNA inhibition using antimiRs in acute human brain tissue sections	23
RNA therapeutics for epilepsy: An emerging modality for drug discovery	23
Response to Effect of antiseizure medications on bone health	23
Topiramate ban in women of childbearing potential with idiopathic generalized epilepsy: Does effectiveness offset the teratogenic risks?	23
Voluntary running wheel activity reduces seizure burden and affords neuroprotection in a mouse model of acquired epilepsy	23
Effectiveness and safety of adjunctive cenobamate in people with focal‐onset epilepsy: Interim results after 24‐week observational period from the BLESS study	22
Automated detection of focal seizures using subcutaneously implanted electrocardiographic device: A proof‐of‐concept study	22
Long‐term characterization of behavior phenotypes in children with seizures: Analytic approach matters	22
Extended follow‐up after anterior temporal lobectomy demonstrates seizure recurrence 20+ years postsurgery	22
Long‐term safety and effectiveness of fenfluramine in children and adults with Dravet syndrome	22
Structural connectivity changes in focal epilepsy: Beyond the epileptogenic zone	22
Both epilepsy and anti‐seizure medications affect bone metabolism in children with self‐limited epilepsy with centrotemporal spikes	22
Long‐term neuroplasticity in language networks after anterior temporal lobe resection	22
Transition from pediatric to adult care system in patients with complex epilepsies: Necker model for transition evaluated on 70 consecutive patients	22
Accumulated seizure burden predicts neurodevelopmental outcome at 36 months of age in patients with tuberous sclerosis complex	21
Role of cholesterol in modulating brain hyperexcitability	21
Evaluation of antiseizure medication concentration ranges in blood samples using an automated big data approach	21
Imaging blood–brain barrier dysfunction in drug‐resistant epilepsy: A multi‐center feasibility study	21
Thank you to our reviewers in 2024	21
Cortical hemodynamics of electrographic status epilepticus in the critically ill	21
Comparative risk of major health events among individuals prescribed different antiseizure medications following ischemic stroke	21
Epileptic spasms and RNA analysis in a new case of Kabuki syndrome type 2	21
Clinical effectiveness, feasibility, acceptability, and usability of mobile health applications for epilepsy: A systematic review	21
The cerebellum in epilepsy	20
Time‐to‐event clinical trial designs: Existing evidence and remaining concerns	20
Long‐term safety and efficacy of adjunctive lacosamide in the treatment of generalized onset tonic–clonic seizures: An open‐label extension trial	20
Cognitive phenotype of juvenile absence epilepsy: An investigation of patients and unaffected siblings	20
Forty‐hertz sensory entrainment impedes kindling epileptogenesis and reduces amyloid pathology in an Alzheimer disease mouse model	20
Evolution in the prescription and cost of non‐intravenous rescue benzodiazepines for the treatment of seizure emergencies	20
Prognostic factors and impact of management strategies for status epilepticus: The STEPPER study in the Emilia‐Romagna region, Italy	20
The level is in the details: Why differences between direct‐acting oral anticoagulants should be considered in the treatment of patients with epilepsy	20
Evaluating the efficacy of prototype antiseizure drugs using a preclinical pharmacokinetic approach	20
Epilepsy and employment: A qualitative interview study with heads of human resources and occupational physicians in Austria — A call for legislative optimization according to the WHO Inters	20

Comorbidities and predictors of health‐related quality of life in Dravet syndrome: A 10‐year, prospective follow‐up study	20
Case for supporting astrocyte energetics in glucose transporter 1 deficiency syndrome	20
Favorable seizure and developmental outcomes without preoperative intracranial electroencephalography in pediatric patients following epilepsy surgery: A single epilepsy center retrospective study	20
The Seizure‐Associated Genes Across Species (SAGAS) database offers insights into epilepsy genes, pathways and treatments	19
The use of automated and AI‐driven algorithms for the detection of hippocampal sclerosis and focal cortical dysplasia	19
Anticonvulsive properties of soticlestat, a novel cholesterol 24‐hydroxylase inhibitor	19
Excitatory–inhibitory mismatch shapes node recruitment in an epileptic network	19
Heterogeneity of patients with functional/dissociative seizures: Three multidimensional profiles	19
A gain‐of‐function GRIA2 variant associated with neurodevelopmental delay and seizures: Functional characterization and targeted treatment	19
Spectrum of epilepsy with eyelid myoclonia: Delineation of disease subtypes from a large multicenter study	19
Somatic variants as a cause of drug‐resistant epilepsy including mesial temporal lobe epilepsy with hippocampal sclerosis	19
Identification of patients with epilepsy using automated electronic health records phenotyping	19
A de novo missense variant in GABRA4 alters receptor function in an epileptic and neurodevelopmental phenotype	19
18F‐SynVesT‐1 positron emission tomography in a hypothalamic hamartoma with abnormal uptake	19
Epilepsy medication management: Addressing common treatment barriers to adopting cenobamate and other new antiseizure medications	19
Increased expression of complement components in tuberous sclerosis complex and focal cortical dysplasia type 2B brain lesions	19
Excitatory/inhibitory balance in epilepsies and neurodevelopmental disorders: Depolarizing γ‐aminobutyric acid as a common mechanism	19
Parental preferences for seizure detection devices: A discrete choice experiment	19
Issue Information	19
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High‐gamma modulation language mapping and cognitive outcomes after epilepsy surgery	18
In‐hospital and home‐based long‐term monitoring of focal epilepsy with a wearable electroencephalographic device: Diagnostic yield and user experience	18
Association of first antiseizure medication with acute health care utilization in a cohort of adults with newly diagnosed epilepsy	18
Task‐based functional magnetic resonance imaging prediction of postsurgical cognitive outcomes in temporal lobe epilepsy: A systematic review, meta‐analysis, and new data	18
Progress report on new antiepileptic drugs: A summary of the Sixteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVI):II. Drugs in more advanced clinical dev	18
Screening for depression in patients with epilepsy: What are the benefits for physicians and patients in the real‐life setting	18
Detecting somatic variants in purified brain DNA obtained from surgically implanted depth electrodes in epilepsy	18
Effects of antiseizure medication withdrawal during the first trimester of pregnancy on seizure control and offspring outcomes	18
Efficiency and safety of high‐dose undiluted intravenous push levetiracetam loading doses compared to intravenous infusion in seizing patients: A retrospective cohort study	18
Rescue therapies for seizure clusters: Pharmacology and target of treatments	18
The extent of cytochrome P450 3A induction by antiseizure medications: A systematic review and network meta‐analysis	18
Considerations for determining the efficacy of new antiseizure medications in children age 1 month to younger than 2 years	18
Efficacy and safety of different oral prednisone tapering courses in adult anti‐NMDAR encephalitis: A multicenter prospective cohort study	18
Prediction of long‐term unprovoked seizures after status epilepticus	17
Seizure underreporting in LGI1 and CASPR2 antibody encephalitis	17
Clinical severity is correlated with age at seizure onset and biophysical properties of recurrent gain of function variants associated with SCN8A‐related epilepsy	17
The hemodynamic response to co‐occurring interictal epileptiform discharges and high‐frequency oscillations localizes the seizure‐onset zone	17
Erratum	17
Issue Information	17
Antiseizure medication treatment pathways for US Medicare beneficiaries with newly treated epilepsy	17
Factors affecting breastfeeding in women with epilepsy	17
Correcting for physiological ripples improves epileptic focus identification and outcome prediction	17
Should substitution monotherapy or combination therapy be used after failure of the first antiseizure medication? Observations from a 30‐year cohort study	17
Erratum	17
Erratum	17
Re‐PROGRAM: The evaluation of a brief intervention program for patients with functional seizures in an outpatient hospital setting	17
Long‐term epilepsy outcome dynamics revealed by natural language processing of clinic notes	17
Pathological neurons generate ripples at the UP‐DOWN transition disrupting information transfer	17
A library of quantitative markers of seizure severity	17
Risk of breakthrough seizures depends on type and etiology of epilepsy	17
Improving prediction of sudden unexpected death in epilepsy: From SUDEP‐7 to SUDEP‐3	17
ERRATUM	17
Epilepsy‐related stigma and attitudes: Systematic review of screening instruments and interventions ‐ Report by the International League Against Epilepsy Task Force on Stigma in Epilepsy	16
Corrigendum to “systematic analysis and comparison of commercial seizure detection software”	16
Disruption of intestinal barrier and endotoxemia after traumatic brain injury: Implications for post‐traumatic epilepsy	16
Scalp high‐frequency oscillation spatial distribution is consistent over consecutive nights, while rates vary with antiseizure medication changes	16
The risk of unprovoked seizure occurrence after status epilepticus in adults	16
Simulated driving in the epilepsy monitoring unit: Effects of seizure type, consciousness, and motor impairment	16
A new perspective on drug‐resistant epilepsy in children with focal cortical dysplasia type 1: From challenge to favorable outcome	16
Prospective, longitudinal, multicenter study on the provision of information regarding sudden unexpected death in epilepsy to adults with epilepsy	16
A web‐based algorithm to rapidly classify seizures for the purpose of drug selection	16
Erratum	16
Epilepsy and its neurobehavioral comorbidities: Insights gained from animal models	16
Blocking receptor for advanced glycation end products (RAGE) or toll‐like receptor 4 (TLR4) prevents posttraumatic epileptogenesis in mice	16
Ring 20 syndrome: A call to action	16
Dynamic tractography‐based localization of spike sources and animation of spike propagations	15
Chronic intracranial recordings after resection for epilepsy reveal a "running down" of epileptiform activity	15
Parallel transmit 7T MRI for adult epilepsy pre‐surgical evaluation	15
Electrographic screening for infantile epileptic spasms syndrome in a single sleep–wake cycle	15
Transcranial direct current stimulation for focal status epilepticus or lateralized periodic discharges in four patients in a critical care setting	15
Clarifications regarding bumetanide for neonatal seizures	15
Magnetic resonance imaging findings and clinical characteristics in mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy in a predominantly adult cohort	15
Use of second doses of Valtoco® (diazepam nasal spray) across 24 hours after the initial dose for out‐of‐hospital seizure clusters: Results from a phase 3, open‐label, repeat‐dose safety study	15
Mitochondrial respiration defects in lymphoblast cell lines from patients with Dravet syndrome	15
Emerging roles of long non‐coding RNAs in human epilepsy	15
Decision‐making in stereotactic epilepsy surgery	15
Automatic video analysis and classification of sleep‐related hypermotor seizures and disorders of arousal	15
Effects of laser interstitial thermal therapy for mesial temporal lobe epilepsy on the structural connectome and its relationship to seizure freedom	15
Lack of clinically relevant differences in safety and pharmacokinetics after second‐dose administration of intranasal diazepam within 4 h for acute treatment of seizure clusters: A population analysis	15
Do all individuals with Dravet syndrome have intellectual disability?	15
Assessing short‐term and long‐term security and efficacy of anterior nucleus of the thalamus deep brain stimulation for treating drug‐resistant epilepsy: A systematic	15
Hippocampal sclerosis and temporal lobe epilepsy following febrile status epilepticus: The FEBSTAT study	14
Detection of interictal epileptiform discharges in an extended scalp EEG array and high‐density EEG—A prospective multicenter study	14
Adjunctive brivaracetam and sustained seizure frequency reduction in very active focal epilepsy	14
Immediate and long‐term management practices of acute symptomatic seizures and epileptiform abnormalities: A cross‐sectional international survey	14
Sulfasalazine decreases astrogliosis‐mediated seizure burden	14
Vitamin B status and association with antiseizure medication in pregnant women with epilepsy	14
Neurocardiac pathologies associated with potassium channelopathies	14
Seizure forecasting: Where do we stand?	14
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Temporal trends in the cost and use of first‐line treatments for infantile epileptic spasms syndrome	14
Permutation entropy‐derived parameters to estimate the epileptogenic zone network	14
Electroencephalography–functional magnetic resonance imaging of epileptiform discharges: Noninvasive investigation of the whole brain	14
Comprehensive phenotypes of patients with SYNGAP1‐related disorder reveals high rates of epilepsy and autism	14
Correction to “Home recording of 3‐Hz spike–wave discharges in adults with absence epilepsy using the wearable Sensor Dot”	14