European Journal of Clinical Investigation

Article	Citations
	143
ACKR3 agonism induces heterodimerization with chemokine receptor CXCR4 and attenuates platelet function	97
Correction to ‘Association Between Exposure to Air Pollution and Blood Lipids in the General Population of Spain’	86
Effects of glucagon‐like PEPTIDE‐1 receptor agonists on incidence of hepatocellular carcinoma and liver decompensation in patients with diabetes: A systematic review and META‐analysis	81
Issue Information	76
Role of PERK‐mediated pathway in the effect of mild hypothermia after cerebral ischaemia/reperfusion	69
Human blood metabolites and risk of severe COVID‐19: A Mendelian randomization study	50
Progress and challenges in the symbiosis of AI with science and medicine	48
Omega‐3 phospholipids and obesity‐associated NAFLD: Potential mechanisms and therapeutic perspectives	44
Clinical predictors of late SARS‐CoV‐2 positivity in Italian internal medicine wards	41
Clinical implications of vascular dysfunction in acute and convalescent COVID‐19: A systematic review	40
New insights into Covid‐19 disease. Apo‐A1 antibodies are generated after mRNA Covid‐19 vaccination and after Covid‐19 infection	36
Clinical outcomes and phylogenetic analysis in reflection with three predominant clades of SARS‐CoV‐2 variants	36
Hydrogen sulphide: Diabetic cardiomyopathy as the paradigm of its pleiotropic function	35
The use of the Crohn's disease exclusion diet (CDED) in adults with Crohn's disease: A randomized controlled trial	33
Does hospitalisation improve oral anticoagulant optimisation in patients with atrial fibrillation?	33
Effects of pharmacological inhibition of hyaluronic acid synthesis on experimental endometriosis	33
Social determinants of health and cardiovascular outcomes in patients with heart failure	32
Clinical use of controlled oxygenated rewarming of kidney grafts prior to transplantation by ex vivo machine perfusion. A pilot study	32
Issue Information	30
Elevated factor XIa as a modulator of plasma fibrin clot properties in coronary artery disease	30
rFVIII‐Fc in severe haemophilia A: The incentive switch in case of high risk of joint bleedings	29
Glucagon and glucagon‐like peptide‐1 dual agonist therapy: A possible future towards fatty kidney disease	28
Seasonal vitamin D levels and lupus low disease activity state in systemic lupus erythematosus	28
Angiotensin‐converting enzyme 2 and transmembrane protease serine 2 in female and male patients with end‐stage kidney disease	27

Impact of sirolimus on long‐term adverse cardiovascular outcomes in kidney transplant recipients: A nationwide cohort study	27
Combination therapy with an SGLT‐2 inhibitor and finerenone in DKD: Are we there yet?	26
Adipocyte maturation impacts daunorubicin disposition and metabolism	25
CONVALESCENT plasma for COVID‐19: A meta‐analysis of clinical trials and real‐world evidence	25
Prognostic significance of echocardiographic deformation imaging in adult congenital heart disease	25
The role of vascular smooth muscle cells in the development of aortic aneurysms and dissections	25
Deep brain stimulation of fornix in Alzheimer's disease: From basic research to clinical practice	24
Mushrooms on the plate: Trends towards NAFLD treatment, health improvement and sustainable diets	24
Refining the role of presurgical PET/4D‐CT in a large series of patients with primary hyperparathyroidism undergoing [18F]Fluorocholine PET/CT	23
A precise review on NAATs‐based diagnostic assays for COVID‐19: A motion in fast POC molecular tests	22
MyofAPPcial: Construct validity of a novel technological aid for improving clinical reasoning in the management of myofascial pain syndrome	22
Cardiac proteomic profiling suggests that hypertrophic and dilated cardiomyopathy share a common pathogenetic pathway of the calcium signalling pathway	22
Blood pressure measurement for prediction of chronic pressure overload and cardiovascular events	22
Concerns regarding interpretation in systematic review of exercise and endothelial glycocalyx	21
Adipose tissue insulin resistance and lipidome alterations as the characterizing factors of non‐alcoholic steatohepatitis	21
ALKBH1 contributes to renal cell carcinoma progression by reducing N6‐methyladenine of GPR137	21
Impaired fibrin clot lysis is associated with increased mortality in patients after coronary artery bypass grafting: A long‐term follow‐up study	21
Incretin system and glucagon secretion in patients with chronic pancreatitis	21
Carcinoembryonic antigen‐related cell adhesion molecule 1 in cancer: Blessing or curse?	20
Markedly elevated serum preoperative thyroglobulin predicts radioiodine‐refractory thyroid cancer	20
Short‐ and long‐term risk stratification in acutely ill medical patients by implementing ankle‐brachial index and pulse wave velocity in the emergency setting	20
The glucagon‐like peptide‐1 receptor agonist semaglutide in diabetic kidney disease: A new kid on the block to afford maximal kidney protection	20
Mineralocorticoid receptor antagonists in kidney transplantation	19
BNT162b2 Vaccine‐Associated Myo/Pericarditis in Adolescents: A Stratified Risk‐Benefit Analysis	19
Hyperventilation testing in the diagnosis of vasospastic angina: A clinical review and meta‐analysis	19
Automatic reorientation algorithm for myocardial perfusion SPECT using segmentation	19
The hinge‐1 domain of Flna is not necessary for diverse physiological functions in mice	18
Cardiovascular benefits of early rhythm control and healthy lifestyle in young atrial fibrillation	18
Osteopontin is associated with neutrophil extracellular trap formation in elderly patients with severe sepsis	18
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The triglyceride‐glucose index as an adiposity marker and a predictor of fat loss induced by a low‐calorie diet	18
No evidence linking sleep traits with white blood cell counts: Multivariable‐adjusted and Mendelian randomization analyses	18
Issue Information	18
Differential utility of various frailty diagnostic tools in non‐geriatric hospital departments of several countries: A longitudinal study	18
Temporal trends of gender disparities in oral anticoagulant use in patients with atrial fibrillation	18
The influence of hypoxia‐mediated CEACAM6 upregulation on epithelial cell and macrophage response in the context of gastric cancer	17
Constructive and obsessive criticism in science	17
Percutaneous coronary revascularization versus medical therapy in chronic coronary syndromes: An updated meta‐analysis of randomized controlled trials	17
Off‐label underdosing of four individual NOACs in patients with nonvalvular atrial fibrillation: A systematic review and meta‐analysis of observational studies	17
The urotensin‐II receptor: A marker for staging and steroid outcome prediction in ulcerative colitis	17
Elevated factor XI is associated with recurrent left ventricular thrombus of unknown origin	17
ELOVL2‐methylation and renal and cardiovascular event in patients with chronic kidney disease	17
Type 2 diabetes and chronic kidney disease as long‐term predictors of cardiovascular events in patients with coronary artery disease	17
Nutrition, cognition and chronic kidney disease: A comprehensive review of interactions and interventions	17
Focal high‐intensity focused ultrasound therapy for localized prostate cancer: An interim analysis of the multinational FASST study	17
Noncommunicable diseases, climate change and iniquities: What COVID‐19 has taught us about syndemic	17
Hydrogen sulphide in liver glucose/lipid metabolism and non‐alcoholic fatty liver disease	16
The role of mean platelet volume in metabolic dysfunction associated steatotic liver disease	16
The ABCG8 polymorphism increases the risk of gallbladder cancer in the general population and gallstones in obese patients from Poland	16
What determines health professionals’ COVID‐19 vaccine hesitancy? A nationwide study	16

Associations of 50 modifiable risk factors with atrial fibrillation using Mendelian randomization analysis	16
Novel cutting edge nano‐strategies to address old long‐standing complications in cardiovascular diseases. A comprehensive review	15
Association between the use of lipid‐lowering drugs and the risk of inflammatory bowel disease	15
Issue Information	15
Obesity paradox in patients with chronic total occlusion of coronary artery	15
Residual risk prediction in anticoagulated patients with atrial fibrillation using machine learning: A report from the GLORIA‐AF registry phase II/III	15
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Cognitive impairment and endothelial dysfunction in convalescent COVID‐19 patients undergoing rehabilitation	15
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Hypercholesterolemia and inflammation—Cooperative cardiovascular risk factors	15
The sodium–chloride difference: A marker of prognosis in patients with acute myocardial infarction	15
Coronary artery calcium score and its association with stroke: A systematic review and meta‐analysis	15
Increased epicardial nerves and decreased intramyocardial PVAT in acute myocardial infarction	14
Artificial‐intelligence‐based decision support tools for the differential diagnosis of colitis	14
Artificial intelligence evaluation of coronary computed tomography angiography for coronary stenosis classification and diagnosis	14
Circulating haematopoietic stem cells and long‐term outcomes of COVID‐19	14
Haemodynamic impact of MitraClip in patients with functional mitral regurgitation and pulmonary hypertension	14
Changing trends in the prevalence of heart failure impairment with Thalassemias over three decades	14
Mortality after transvenous lead extraction: A risk prediction model for sustainable care delivery	14
The skin microbiome of infected pressure ulcers: A review and implications for health professionals	14
Issue Information	14
Impact of stroke history on procedural cerebrovascular insult probability and long‐term outcome after TAVI	13
A systematic review and meta‐analysis on oncological radiotherapy in patients with a cardiac implantable electronic device: Prevalence and predictors of device malfunction in 3121 patients	13
Serum fibulin‐1 levels and target organ damage in patients at high cardiovascular risk: A prospective observational study	13
Targeting the SPHK1/S1P/S1PR2 axis ameliorates GH‐secreted pituitary adenoma progression	13
Synovial expression of glucocorticoid receptor parallels fibroblast activation in patients with rheumatoid arthritis	13
Role of the electrocardiogram in differentiating genetically determined dilated cardiomyopathy from athlete's heart	13
Open Access Publications is our mission in 2022: perspective from the editors of the European Journal of Clinical Investigation	13
Statin treatment reduces protein carbonylation in patients with COPD: A randomized controlled study	13
Cystatin C‐estimated GFR correlates with endothelial function improvements following bariatric surgery	13
Psychiatric disorders and Type 2 diabetes mellitus: A bidirectional Mendelian randomization	13
Heart, kidney and left ventricular assist device: a complex trio	12
Reciprocity between the regulation of the expression and functions of CEACAM	12
Fatigue and itch severity in patients with PBC and PSC: Prospective analysis of two large cohorts	12
Author index	12
Is there an ‘ideal’ diet for patients with NAFLD?	12
Sentinel lymph node biopsy for breast cancer during pregnancy: A comprehensive update	12
Fatty kidney: A possible future for chronic kidney disease research	12
Antithrombotic therapy and clinical outcomes at 1 year in the Spanish cohort of the EORP‐AF Long‐term General Registry	12
The effect of subcutaneous dulaglutide on weight loss in patients with Type 2 diabetes mellitus: Systematic review and meta‐analysis of randomized controlled trials	12
The role of artificial intelligence in cardiovascular research: Fear less and live bolder	12
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Issue Information	12
Similarities between fibroblasts and cardiomyocytes in the study of the permeability transition pore	12
Risk of gonadotoxicity with immunotherapy and targeted agents remains an unsolved but crucial issue	12
The association between the basal metabolic rate and cardiovascular disease: A two‐sample Mendelian randomization study	12
Nomogram for stratifying patients with lifelong premature ejaculation before using the PHQ‐9: An observational study	12
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Issue Information	11
In‐house editorials and journalistic pieces comprise a massive corpus in the scientific literature that can be improved	11
Issue Information	11
Prognostic impact of abnormal sodium burden in heart failure patients with preserved ejection fraction	11
Association of aortic stiffness early post myocardial infarction with left ventricular remodelling	11
Clinical measures in chronic neuropathic pain are related to the Kennedy and endocannabinoid pathways	11
CHA2DS2‐VASc impact on risk following percutaneous coronary intervention in atrial fibrillation	11
Membrane oxygenator longevity was higher in argatroban‐treated patients undergoing vvECMO	11
Respiratory dysfunction in old mice could be related to inflammation and lung fibrosis induced by hyperphosphatemia	11
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Issue Information	11
Triglyceride‐glycaemic index: Insights into predicting fetal macrosomia and its interaction with gestational diabetes mellitus: A cohort study of Chinese pregnant women	11
Issue Information	11
Anthropometric measures, predicted visceral adipose tissue and biomarkers of chronic inflammation	11
Total lesion glycolysis is a promising predictor of chemo‐response in pancreatic cancer patients treated with neoadjuvant chemotherapy prior to surgery	11
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Issue Information	11
When less is more: The association between the expression of polymorphic CYPs and AFB1‐induced HCC	11
The role of microbiota in nonalcoholic fatty liver disease	11
Shorter periconception maternal telomere length and the risk of congenital cardiac outflow defects in the offspring	11
Prehospital seizures: Short‐term outcomes and risk stratification based in point‐of‐care testing	11
Abstract	11
Circulation tumour DNA in predicting recurrence and prognosis in operable colorectal cancer patients: A meta‐analysis	11
Localization of accessory pathways in Wolff‐Parkinson‐white syndrome using ECG‐based multi‐task deep learning	11
Impact of prior oral anticoagulation therapies on post‐discharge outcomes after COVID‐19: Results from a global federated health network analysis	10
Advanced biomedical imaging for accurate discrimination and prognostication of mediastinal masses	10
Novel 3D versus traditional transesophageal echocardiography techniques: Defining differences in the diagnosis of infective endocarditis	10
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Targeting nicotinamide N‐methyltransferase decreased aggressiveness of osteosarcoma cells	10
Six‐minute walking distance and desaturation–distance ratio in allogeneic stem cell transplantation	10
Evidence base for yearly respiratory virus vaccines: Current status and proposed improved strategies	10
Burden of hypertensive heart disease and its attributable risk factors in 204 countries and territories, 1990–2021: Results from the global burden of disease study 2021	10

Increased body mass index is associated with sarcopenia and related outcomes	10
Long‐term risk of delayed postoperative Crohn's disease recurrence in patients with no or mild endoscopic recurrence at first assessment	10
Issue Information	10
Machine learning in cardiovascular risk assessment: Towards a precision medicine approach	10
Poor self‐reported sleep is associated with risk factors for cardiovascular disease: A cross‐sectional analysis in half a million adults	10
56th Annual Scientific Meeting, 8–10 June 2022, Bari, Italy, “Promoting Biomedical Research, Equal Health and Environment in the post‐COVID Syndemic Era”	9
Gender differences on healthcare accessibility and outcomes of a electronic inter‐clinician consultation program at the cardiology department in a Galician Health Area	9
Antihypertensive treatment changes and related clinical outcomes in older hospitalized patients	9
Body composition markers are more strongly associated with type 2 diabetes than inflammatory markers—Results from the study of health in Pomerania	9
Promising biomarker panel to monitor therapeutic efficacy of neoadjuvant chemotherapy in pancreatic cancer patients	9
Decompressive surgery in cerebral venous thrombosis: A systematic review and meta‐analysis	9
Preprocedural assessment of coronary artery disease in patients undergoing transcatheter aortic valve implantation: Rationale and design of the EASE‐IT CT registry	9
Ambulatory central BP and arterial stiffness in patients with and without intradialytic hypertension	9
Ramadan intermittent fasting reduces visceral fat and improves gastrointestinal motility	9
The autonomic nervous system and bone health in chronic kidney disease	9
Abnormal circulating steroids refine risk of progression to heart failure in ischemic heart disease	9
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Risk prediction of atrial fibrillation and its complications in the community using hs troponin I	9
Issue Information	9
Microvascular disease increases the risk of lower limb amputation – A Western Danish cohort study	9
Issue Information	9
Extracellular matrix mechanical cues (dys)regulate metabolic redox homeostasis due to impaired autophagic flux	9
Sex disparities for patients with atrial fibrillation in the direct oral anticoagulant era	9
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Sotatercept in pulmonary hypertension and beyond	9
Risk of cardiovascular disease in elderly subjects with obesity and liver fibrosis and the potential benefit of statin treatment	8
Low triiodothyronine syndrome is associated with stroke‐associated pneumonia	8
Meta‐analysis of factors associated with antidiabetic drug prescribing for type 2 diabetes mellitus	8
Impact of oncologic diseases on outcome in patients with severe isolated tricuspid regurgitation	8
Issue Information	8
Assessing cardiorespiratory fitness relative to sex improves surgical risk stratification	8
Depression in nonalcoholic fatty liver disease and all‐cause/cause‐specific mortality	8
Global, regional and national burden of alopecia areata and its associated diseases, 1990–2019: A systematic analysis of the Global Burden of Disease Study 2019	8
Heart failure in patients is associated with downregulation of mitochondrial quality control genes	8
Distant metastasis and prognostic factors in patients with invasive ductal carcinoma of the breast	8
Isoprostane‐8 and GDF‐15 as novel markers of post‐PE syndrome: Relation with prothrombotic factors	8
Effects of NAD+ precursors on blood pressure, C‐reactive protein concentration and carotid intima‐media thickness: A meta‐analysis of randomized controlled trials	8
The definition of long COVID used in interventional studies	8
First‐line diagnostic tests to intercept primary heart involvement in systemic sclerosis: Clinical associations from the SPRING‐SIR registry	8
Common misconceptions of randomized controlled trials in oncology	8
ESCI Newsletter	8
One‐hour post‐load glucose and subclinical left atrial myocardial dysfunction in hypertensive patients	8
The influence of viral protein R amino acid substitutions on clinical outcomes in people living with HIV: A systematic review	8
Recent advances in multimodality imaging‐guided therapy in pericarditis	8
Genetic evidence for the causal linkage between telomere length and aortic aneurysm risk: A Mendelian randomisation study	7
Issue Information	7
Sex‐specific and hormone‐related differences in vascular remodelling in atherosclerosis	7
A Mendelian randomization study on causal effects of leisure sedentary behaviour on the risk of rheumatoid arthritis	7
An online nomogram of acute respiratory distress syndrome originating from pulmonary disease	7
Enoxaparin for thromboprophylaxis in hospitalized COVID‐19 patients: The X‐COVID‐19 Randomized Trial	7
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Cancer and cardiovascular diseases: A deadly combination	7
Zinc finger proteins and ATP‐binding cassette transporter‐dependent multidrug resistance	7
Issue Information	7
Sexual dimorphism in exercise‐induced response on steroid hormones to a 24‐week supervised concurrent training intervention	7
Liraglutide modulates morpho‐functional and inflammatory gastrointestinal responses in rats	7
Corrigendum	7
‘Obesities’: Position statement on a complex disease entity with multifaceted drivers	7
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LINC02605 involved in paediatric Mycoplasma pneumoniae pneumonia complicated with diarrhoea via miR‐539‐5p/CXCL1 axis	7
Use of rivaroxaban attenuates renal function impairment in patients with atrial fibrillation: insights of the EMIR study	7
Enhanced neutrophil extracellular traps formation in AF patients with dilated left atrium	7
Major bleeding in patients with pulmonary embolism presenting with syncope	7
Current investigation of carcinoembryonic antigen cell adhesion molecule (CEACAM) biology summary of the 32nd CEA symposium: 20–23 September 2024. Würzburg, Germany	7
Angiotensin converting enzyme 2 level and its significance in COVID‐19 and other diseases patients	7
Issue Information	7
Yield of bone scintigraphy screening for transthyretin‐related cardiac amyloidosis in different conditions: Methodological issues and clinical implications	7
Erythrocyte membrane fluidity: A novel biomarker of residual cardiovascular risk in type 2 diabetes	7
Frailty trajectories in community‐dwelling older adults during COVID‐19 pandemic: The PRESTIGE study	7
Deep learning for electrocardiogram interpretation: Bench to bedside	7
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Sex‐associated differences in cardiac ageing: Clinical aspects and molecular mechanisms	7
Thyroid hormone Beta receptor agonists for treatment of kidney disease: A promising agent?	6
Social isolation and loneliness: Undervalued risk factors for disease states and mortality	6
Methodological and statistical considerations: Batch‐dependent adverse effects of COVID‐19 vaccines	6
Frequent sauna bathing may reduce chronic obstructive pulmonary disease risk: A prospective study	6
Transsulfuration and folate pathways in rheumatoid arthritis: A systematic review and meta‐analysis	6
miR‐619‐5p and cardiogenic shock in patients with ST‐segment elevation myocardial infarction	6
Serological markers and long COVID—A rapid systematic review	6
Catheter‐related deep vein thrombosis: Where are we at and where are we going? Updates and ongoing unmet clinical needs	6
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Mesenchymal stem cells for lysosomal storage and polyglutamine disorders: Possible shared mechanisms	6
Comparison of high‐sensitive cardiac troponin T and I in patients with chronic coronary syndrome	6
Infectious mononucleosis is associated with an increased incidence of NAFLD	6
Proprotein convertase subtilisin/kexin type 9 (PCSK9) and clinical outcomes in patients with end‐stage renal disease	6
Plasma lipoprotein(a) is associated with calcification activity of the thoracic aorta and aortic valve in statin naïve individuals with diabetes mellitus	6
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Redox profiles of amyotrophic lateral sclerosis lymphoblasts with or without known SOD1 mutations	6
Cardiac and renal outcomes of direct oral anticoagulants in patients with atrial fibrillation	6
The body mass index increases the genetic risk scores' ability to predict risk of hepatic damage in European adolescents: The HELENA study	6
Issue Information	6
Central role of pro‐IGFII(68–88) (big IGFII) in the pathogenesis nonislet cell tumour‐induced hypoglycaemia	6
A weekly 4‐methylpyrazole treatment attenuates the development of non‐obese metabolic dysfunction‐associated steatotic liver disease (MASLD) in male mice: Role of JNK	6
Fatal attractions that trigger inflammation and drive atherosclerotic disease	6
Response rate in cardiac resynchronization therapy patients implanted with a left ventricular quadripolar lead and the MultiPoint™ pacing feature early activated. QUARTO III	6