OOIR: Observatory of International Research

Papers

(The TQCC of European Journal of Immunology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Transglutaminase 2 affinity and enzyme‐substrate intermediate stability as determining factors for T‐cell responses to gluten peptides in celiac disease	367
Impressum	83
Impressum	81
Inborn errors of immunity and immunodeficiencies: Antibody‐mediated pathology and autoimmunity as a consequence of impaired immune reactions	74
Termination of CD40L co‐stimulation promotes human B cell differentiation into antibody‐secreting cells	69
Linking Epitope‐Specific T‐Cell Receptors to IFNγ Secretion Using Nanovial Technology	61
Fate‐mapping studies in inbred mice: A model for understanding macrophage development and homeostasis?	57
Surface CD69‐Negative CD4 and CD8 Bone Marrow‐Resident Human Memory T Cells	56
The potential of γδ CAR and TRuC T cells: An unearthed treasure	55
Mast cells in type 2 skin inflammation: Maintenance and function	48
The Streptomyces Metabolite Thiostrepton Inhibits Regulatory T Cell Differentiation and Function to Boost Antitumor Immune Responses	47
Airway epithelial type‐2 alarmin profiles: Blood eosinophil counts remain in memory	47
Four challenges to CAR T cells breaking the glass ceiling	41
B‐cell modulation with anti‐CD79b antibodies ameliorates experimental autoimmune encephalitis in mice	41
Integrin activation enables rapid detection of functional Vδ1⁺ and Vδ2⁺ γδ T cells	41
Metabolic dynamics instruct CD8⁺ T‐cell differentiation and functions	40
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France	40
Cover Story: Eur. J. Immunol. 4'23	39
Intrahepatic plasma cells, but not atypical memory B cells, associate with clinical phases of chronic hepatitis B	38
Bead‐by‐bead normalization of single antigen assays: A necessary step for accurate detection of weak anti‐HLA antibodies	37
Issue Information: Eur. J. Immunol. 10'21	33
Fluorochrome‐labeled inhibitors of caspase‐1 require membrane permeabilization to efficiently access caspase‐1 in macrophages	32
Dimethyl itaconate selectively targets inflammatory and metabolic pathways in chronic lymphocytic leukemia	32
Immunomodulation under the lens of real‐time in vivo imaging	32
In memoriam Martin Röllinghoff (1941–2022)	31

Guidelines for mouse and human DC functional assays	30
Epigenetic Regulation of CD8⁺ Effector T Cell Differentiation by PDCD5	30
Immune signature of patients with cardiovascular disease predicts increased risk for a severe course of COVID‐19	29
Sustained innate interferon is an essential inducer of tertiary lymphoid structures	29
Neutrophil subsets in noncancer liver diseases: Cellular crosstalk and therapeutic targets	29
Staphylococcus aureus‐derived factors promote human Th9 cell polarization and enhance a transcriptional program associated with allergic inflammation	29
Emerging roles of host and microbial bioactive lipids in inflammatory bowel diseases	28
Immunoregulation of asthma by type 2 cytokine therapies: Treatments for all ages?	28
In this issue	27
	27
Current research and unmet needs in allergy and immunology in Germany: report presented by the DGfI and DGAKI task force Allergy & Immunology	27
Regulatory T cells as a therapeutic approach for inflammatory bowel disease	27
AK2‐Deficient Mice Recapitulate Impaired Lymphopoiesis of Reticular Dysgenesis Patients, but Also Lack Erythropoiesis	26
E‐Cadherin restricts mast cell degranulation in mice	26
The VEGF‐Mediated Cytoprotective Ability of MIF‐Licensed Mesenchymal Stromal Cells in House Dust Mite‐Induced Epithelial Damage	26
BOB.1/OBF.1 is required during B‐cell ontogeny for B‐cell differentiation and germinal center function	26
Paradoxical immunodeficiencies—When failures of innate immunity cause immunopathology	25
Enhanced in vitro type 1 conventional dendritic cell generation via the recruitment of hematopoietic stem cells and early progenitors by Kit ligand	25
YF17D‐based vaccines – standing on the shoulders of a giant	23
Potentiation of the axis involving pentose phosphate pathway/NADPH oxidase/reactive oxygen species drives higher IL‐10 production in monocytes of Sub‐Saharan Africans	23
IQGAP1 Influences Neutrophil Maturation and Its Effector Functions	23
Innate immunity champions: The diverse functions of macrophages	22
Fully functional monocytic MDSC generation from the murine HoxB8 cell line	22
Immunomodulation of neutrophil granulocyte functions by bacterial polyphosphates	21
LCMV induced downregulation of HVEM on antiviral T cells is critical for an efficient effector response	21
T‐cell signature cytokines distinguish pulmonary sarcoidosis from pulmonary tuberculosis	21
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Global k_off‐rates of polyclonal T‐cell populations merge subclonal avidities and predict functionality	21
The Young Immunologists' Podcast: Immunology and Much More	20
Cytokine Autoantibodies Alter Gene Expression Profiles of Healthy Donors	19
Issue Information: Eur. J. Immunol. 8'23	19
Functional Fc receptors are crucial in antibody‐mediated protection against cytomegalovirus	19
Czech Young Immunologists: Bound by science, united in purpose	19
IL‐4, IL‐15, and Type I Interferon Orchestrate the Shaping of the Heterogeneity of Virtual Memory CD8 T Cells	19
Communication and transparency at EJI: Supporting authors through their publishing experience	19
Researcher Reflections—Inspiring Paths in Academia	18
Mouse dendritic cells and other myeloid subtypes in healthy lymph nodes and skin: 26‐Color flow cytometry panel for immune phenotyping	18
Issue Information: Eur. J. Immunol. 1'25	18
Immediate major dynamic changes in the T‐ and NK‐cell subset composition after cardiac transplantation	18
Cover Story: Eur. J. Immunol. 1'24	18
Novel homozygous CD46 variant with C‐isoform expression affects C3b inactivation in atypical hemolytic uremic syndrome	17
TLR9‐Driven S‐Palmitoylation in Dendritic Cells Reveals Immune and Metabolic Protein Targets	17
Differential regulation of CD8⁺CD86⁺ Vγ1.1⁺ γδT cell responses in skin barrier tissue protection and homeostatic maintenance	17
Metabolic reprograming shapes neutrophil functions in severe COVID‐19	17
B Cell Receptor Repertoire Analysis of the CD21^lo B Cell Compartment in Healthy Individuals, Patients With Sjögren's Disease, and Patients With Radiographic Axial Spondyloarthritis	17
	17
Key actors in neuropathophysiology: The role of γδ T cells	17
Immunology meeting	16
In this issue	16
MicroRNA‐146a deficiency enhances host protection against murine cytomegalovirus	16

Impressum	16
Acquired immune resistance is associated with interferon signature and modulation of KLF6/c‐MYB transcription factors in myeloid leukemia	16
The Swiss Young Immunologists Society (SYIS): Empowering the next generation of immunologists	16
PP2A catalytic subunit alpha is critically required for CD8⁺ T‐cell homeostasis and antibacterial responses	16
Impressum	16
EFIS News	16
Distinct Tissue‐Dependent Composition and Gene Expression of Human Fetal Innate Lymphoid Cells	16
Tyrosine kinase inhibitor cabozantinib impacts dendritic and natural killer cells immune response in C38 syngeneic tumor model	15
Contents: Eur. J. Immunol. 11'22	15
Release of IL‐1β and IL‐18 in human primary bronchial epithelial cells exposed to cigarette smoke is independent of NLRP3	15
Contents: Eur. J. Immunol. 12'21	15
Sex‐specific impact of psychosocial stress on hematopoiesis and blood leukocytes	15
Knockout of SLy1 decreases double‐negative thymocyte proliferation and protects mice from p53‐induced tumor formation	15
In this issue	15
Journal roundup	15
Langerhans cells orchestrate apoptosis of DNA‐damaged keratinocytes upon high‐dose UVB skin exposure	15
Endogenous secretory leukocyte protease inhibitor inhibits microbial‐induced monocyte activation	15
Contents: Eur. J. Immunol. 7'22	15
Dendritic cells generated from induced pluripotent stem cells and by direct reprogramming of somatic cells	15
Pamidronate‐Induced Clinical Remission in Chronic Non‐bacterial Osteomyelitis Is Associated with Reduced Vγ9Vδ2 T‐Cell Receptor Expression	14
Human cDC1s display constitutive activation of the UPR sensor IRE1	14
Intestinal homeostasis and inflammation: Gut microbiota at the crossroads of pancreas–intestinal barrier axis	14
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	14
Expanding our understanding of Guillain–Barré syndrome: Recent advances and clinical implications	14
Microenvironmental signals shaping NK‐cell reactivity in cancer	14
Nonreplicating synthetic mRNA vaccines: A journey through the European (Journal of Immunology) history	14
Exploring How Cytoskeleton Dynamics Tunes T Cell Activation at the Immunological Synapse	14
Single‐cell multi‐omics analysis of COVID‐19 patients with pre‐existing autoimmune diseases shows aberrant immune responses to infection	13
Helios is a marker, not a driver, of human Treg stability	13
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Methiothepin downregulates SNAP‐23 and inhibits degranulation of rat basophilic leukemia cells and mouse bone marrow‐derived mast cells	13
Proteomics reveals a global phenotypic shift of NK cells in HCV patients treated with direct‐acting antivirals	13
Actinin‐4 controls survival signaling in B cells by limiting the lateral mobility of B‐cell antigen receptors	13
Guidelines for mouse and human DC generation	13
Differential Runx3, Eomes, and T‐bet expression subdivides MS‐associated CD4⁺ T cells with brain‐homing capacity	13
Altered increase in STAT1 expression and phosphorylation in severe COVID‐19	13
SARS‐CoV‐2‐specific T cells are generated in less than half of allogeneic HSCT recipients failing to seroconvert after COVID‐19 vaccination	13
Georg Friedrich (Fritz) Melchers (27.4.1936–24.2.2025)	13
Therapeutic targeting of factor D and MASP3 in complement‐mediated diseases: Lessons learned from mouse studies	13
The immunosuppressive drug cyclosporin A has an immunostimulatory function in CD8⁺ T cells	13
DsbA‐L deletion attenuates LPS‐induced acute kidney injury by modulating macrophage polarization	13
	13
Cover story: Eur. J. Immunol. 7'22	13
Resolution of Autoimmune Uveitis Requires CCL20‐Dependent Regulatory T Cells	13
Correction	13
A human immune system (HIS) mouse model that dissociates roles for mouse and human FcR⁺ cells during antibody‐mediated immune responses	12
Impressum	12
In this issue	12
Portuguese Society of Immunology (SPI): Turning 50, inspired by the past, looking into the future	12
Lymphotoxins from distinct types of lymphoid cells differentially contribute to neuroinflammation	12
Issue Information: Eur. J. Immunol. 7'23	12
Diversity of regulatory B cells: Markers and functions	12
Bin‐based visualization of cytokine‐co‐expression patterns of IL‐10‐producing CD4 T cell subsets	12
Impressum	12
Detection of dendritic cell subsets in the tumor microenvironment by multiplex immunohistochemistry	12
Acellular Pertussis Vaccines Induce CD8⁺ and CD4⁺ Regulatory T Cells That Suppress Protective Tissue‐Resident Memory CD4⁺ T Cells, in Part via IL‐10	12
Booster Injection with Birch Pollen Extract Activates B‐Cellular Memory Responses in Patients Having Completed Allergen Immunotherapy	12
From simple to complex: Protein‐based biomarker discovery in tuberculosis	12
Interleukin‐2‐induced skin inflammation	12
SIRPα: A key player in innate immunity	12
Puppet masters of B‐cell progenitor acute lymphoblastic leukemia: The preB cell receptor and the interleukin 7 receptor α	12
Augmented neutralization of SARS‐CoV‐2 Omicron variant by boost vaccination and monoclonal antibodies	12
Cover Story: Eur. J. Immunol. 12'23	12
Human T Cell Responses to Flavivirus Vaccines	12
TLR4 phosphorylation at tyrosine 672 activates the ERK/c‐FOS signaling module for LPS‐induced cytokine responses in macrophages	11
CCR4⁺CD8⁺ T cells clonally expand to differentiated effectors in murine psoriasis and in human psoriatic arthritis	11
Specificity of mouse and human Fcgamma receptors and their polymorphic variants for IgG subclasses of different species	11
Epigenetic Regulations in Autoimmunity and Cancer: from Basic Science to Translational Medicine	11
Regulation of B‐cell function and expression of CD11c, T‐bet, and FcRL5 in response to different activation signals	11
Inhibition of Melanoma Growth by Ex Vivo Expanded Tumor‐Specific CD8+ T Cells Is Dependent on the Configuration of Nanoscale Artificial APCs	11
Characterization of human CD4⁺EOMES⁺GzmK⁺ T‐cell subsets unveils an uncoupling of suppressive functions from IL‐10‐producing capacities	11
PIEZO1‐mediated mechanosensing governs NK‐cell killing efficiency and infiltration in three‐dimensional matrices	11
Effect of Aspirin Challenge on Innate Lymphoid Cells in Asthma Patients With Aspirin Hypersensitivity	11
Molecular and functional in vivo characterisation of murine Dectin‐1 isoforms	11
Antibiotic use during pregnancy is linked to offspring gut microbial dysbiosis, barrier disruption, and altered immunity along the gut–lung axis	11
PDGFRα‐lineage origin directs monocytes to trafficking proficiency to support peripheral immunity	11
TLR2 on CD4+ and CD8+ T cells promotes control of Mycobacterium tuberculosis infection	10
Immunogenicity‐Guided Design of an Acinetobacter baumanii Vaccine	10
Crafting an MSCA PhD Masterpiece: Guiding Students on the Verge of Discovery	10

Neural Crest‐Derived Mesenchymal Cells Support Thymic Reconstitution After Lethal Irradiation	10
Issue Information: Eur. J. Immunol. 1'23	10
Characterization of SARS‐CoV‐2 and common cold coronavirus‐specific T‐cell responses in MIS‐C and Kawasaki disease children	10
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The first year of young group of the Spanish Immunology Society: Progress, challenges, and next steps	10
TNF Production or TNFR2 Expression Characterize Distinct States of Regulatory T Cells that Cooperate in Treg Expansion in Cancer and Chronic Inflammation	10
High Extracellular K⁺ Skews T‐Cell Differentiation Towards Tumour Promoting Th2 and T_reg Subsets	10
Autoimmunity and SARS‐CoV‐2 infection: Unraveling the link in neurological disorders	10
Guidelines for DC preparation and flow cytometry analysis of mouse lymphohematopoietic tissues	10
Survival of Human Bone Marrow Plasma Cells In Vitro Depends on the Support of the Stromal Cells, PI3K, and Canonical NF‐kappaB Signaling	10
Front cover story: Eur. J. Immunol. 2'22	10
	10
Compartmentalized multicellular crosstalk in lymph nodes coordinates the generation of potent cellular and humoral immune responses	10
Impressum	10
Cover Story: Eur. J. Immunol. 8'23	10
Impressum	10
Effects of altered salt intake and diet on cytokines in humans: A 20‐week randomized cross‐over intervention study	10
Cover Story: Eur. J. Immunol. 5'24	10
Bystander activation of tissue‐resident memory CD4 T cells: Getting by with a little help from unfamiliar T‐cell friends	10
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	10
Contents: Eur. J. Immunol. 8'22	10
Chronic stimulation desensitizes β2‐adrenergic receptor responses in natural killer cells	9
Vitamin A‐treated natural killer cells reduce interferon‐gamma production and support regulatory T‐cell differentiation	9
IL1R2 Acts as a Negative Regulator of Monocyte Recruitment During Inflammation	9
In this issue	9
Plasmodium berghei Radiation‐Attenuated Sporozoite‐Immunized Mice Require Infectious Sporozoite Challenge to Maintain Protective Immunity	9
Interleukin 23 receptor: Expression and regulation in immune cells	9
Translational immunology: Applying fundamental discoveries to human health and autoimmune diseases	9
Baseline Single‐Cell Differences in Polyfunctionality Between Systemic Autoinflammatory Diseases Patients and Healthy Controls	9
Cover Story: Eur. J. Immunol. 4'25	9
Dendritic cells Trigger IFN‐γ secretion by NK cells independent of IL‐12 and IL‐18	9
Retinoic acid‐loaded liposomes induce human mucosal CD103⁺ dendritic cells that inhibit Th17 cells and drive regulatory T‐cell development in vitro	9
Upregulation of IL4‐induced gene 1 enzyme by B2 cells during melanoma progression impairs their antitumor properties	9
yEFIS 1^st Symposium: Shaping the future of Immunology in Europe, 10–11 November, 2022, Berlin, Germany	9
yEFIS with EFIS Lead the Way to ECR Engagement at ECI2024	9
Fine needle aspiration of human lymph nodes reveals cell populations and soluble interactors pivotal to immunological priming	8
Follicular helper T cell signature of replicative exhaustion, apoptosis, and senescence in common variable immunodeficiency	8
	8
ICAP‐1 loss impairs CD8⁺ thymocyte development and leads to reduced marginal zone B cells in mice	8
Zfp362 potentiates murine colonic inflammation by constraining Treg cell function rather than promoting Th17 cell differentiation	8
	8
Sphingosine‐1‐phosphate receptor type 4 is critically involved in the regulation of peritoneal B‐1 cell trafficking and distribution in vivo	8
Autoantibodies targeting type I interferons: Prevalence, mechanisms of induction, and association with viral disease susceptibility	8
Impressum	8
Therapeutic tactics for targeting B lymphocytes in autoimmunity and cancer	8
Combined Deletion of ZFP36L1 and ZFP36L2 Drives Superior Cytokine Production in T Cells at the Cost of Cell Fitness	8
Interferon α and β induce differential transcriptional and functional metabolic phenotypes in human macrophages and blunt glycolysis in response to antigenic stimuli	8
Foxp3⁺ regulatory T cells in the central nervous system and other nonlymphoid tissues	8
PD‐L2 Inhibits Protective Immunity, Th2 Cell Functional Quality, and GATA‐3 Expression During Filarial Nematode Infection	8
	8
Impact of the adenosine receptor A2BR expressed on myeloid cells on immune regulation during pregnancy	8
Sensing context: Inhibitory receptors on non‐hematopoietic cells	8
MicroRNAs targeting TGF‐β signaling exacerbate central nervous system autoimmunity by disrupting regulatory T cell development and function	8
PAD2 immunization induces ACPA in wild‐type and HLA‐DR4 humanized mice	8
Immunity in malignant brain tumors: Tumor entities, role of immunotherapy, and specific contribution of myeloid cells to the brain tumor microenvironment	8
Trametinib Suppresses the Stimulated T Cells Through G1 Arrest and Apoptosis	8
Regulation of DC metabolism by nitric oxide in murine GM‐CSF cultures	8
Polymorphism in F pocket affects peptide selection and stability of type 1 diabetes‐associated HLA‐B39 allotypes	8
T helper cell subsets: diversification of the field	8
Prmt5 deficient mouse B cells display RNA processing complexity and slower colorectal tumor progression	8
Characteristics and mechanisms of T‐cell senescence: A potential target for cancer immunotherapy	8
Cover Story: Eur. J. Immunol. 11'23	8
SARS‐CoV‐2 variants of concern elicit divergent early immune responses in hACE2 transgenic mice	8
Verteporfin protects against Th17 cell‐mediated EAE independently of YAP inhibition	8
Influence of SLAM Family Receptors in the NK‐Cell‐Mediated Surveillance of Lymphoblastic Acute Leukemia	8
	7
Dynamics of IL‐15/IL‐15R‐α expression in response to HSV‐1 infection reveal a novel mode of viral immune evasion counteracted by iNKT cells	7
CD95L concatemers highlight different stoichiometries of CD95‐mediated apoptotic and nonapoptotic pathways	7
Cover Story: Eur. J. Immunol. 8'24	7
Issue Information: Eur. J. Immunol. 5'25	7
	7
Advances in experimental models of rheumatoid arthritis	7
In this issue	7
	7
	7
Deciphering the Human Germinal Center: A Review of Models to Study T–B Cell Interactions	7
The complement system: A key player in the host response to infections	7
Composition of fatty acids in a high‐fat diet affects adipose tissue inflammation by inducing calreticulin on adipocytes and activating group 1 innate lymphoid cells	7
Antibody density on bacteria regulates C1q recruitment by monoclonal IgG but not IgM	7
Impressum	7
Identification and Mapping of Human Lymph Node Stromal Cell Subsets by Combining Single‐Cell RNA Sequencing with Spatial Transcriptomics	7
Neutralizing antibodies to SARS‐CoV‐2 Omicron variant after third mRNA vaccination in health care workers and elderly subjects	7
Contents: Eur. J. Immunol. 1'22	7
	7
Altered IgG glycosylation at COVID‐19 diagnosis predicts disease severity	7
Rational design of polymer‐based particulate vaccine adjuvants	7
Cover Story: Eur. J. Immunol. 4'24	7
GPR109A expressed on medullary thymic epithelial cells affects thymic Treg development	7
Meeting Report: German–Japanese Alliance in Immunology	7
TOX Does Not Drive Sepsis‐Induced T‐Cell Exhaustion	7
PBMC‐derived extracellular vesicles in a smoking‐related inflammatory disease model	7
NK Cell Immaturity and NKp30 Expression Positively Correlate with Clinical Outcome in Multiple Myeloma Patients from the IFM2009 Clinical Trial	7
Issue Information: Eur. J. Immunol. 11'22	6
Issue Information: Eur. J. Immunol. 12'24	6