OOIR: Observatory of International Research

Papers

(The TQCC of European Journal of Immunology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Impressum	98
Impressum	85
Linking Epitope‐Specific T‐Cell Receptors to IFNγ Secretion Using Nanovial Technology	64
Transglutaminase 2 affinity and enzyme‐substrate intermediate stability as determining factors for T‐cell responses to gluten peptides in celiac disease	64
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France	60
Immunomodulation under the lens of real‐time in vivo imaging	57
Cover Story: Eur. J. Immunol. 4'23	57
Termination of CD40L co‐stimulation promotes human B cell differentiation into antibody‐secreting cells	51
Integrin activation enables rapid detection of functional Vδ1⁺ and Vδ2⁺ γδ T cells	47
Immune signature of patients with cardiovascular disease predicts increased risk for a severe course of COVID‐19	46
Bead‐by‐bead normalization of single antigen assays: A necessary step for accurate detection of weak anti‐HLA antibodies	46
The potential of γδ CAR and TRuC T cells: An unearthed treasure	45
Guidelines for mouse and human DC functional assays	42
TEAMwork: Interplay of Post‐Transcriptional Mechanisms, Epigenetics and Metabolism in (Auto‐)Immunity	42
The Streptomyces Metabolite Thiostrepton Inhibits Regulatory T Cell Differentiation and Function to Boost Antitumor Immune Responses	39
B‐cell modulation with anti‐CD79b antibodies ameliorates experimental autoimmune encephalitis in mice	39
Four challenges to CAR T cells breaking the glass ceiling	38
Inborn errors of immunity and immunodeficiencies: Antibody‐mediated pathology and autoimmunity as a consequence of impaired immune reactions	36
Fluorochrome‐labeled inhibitors of caspase‐1 require membrane permeabilization to efficiently access caspase‐1 in macrophages	33
In memoriam Martin Röllinghoff (1941–2022)	33
Airway epithelial type‐2 alarmin profiles: Blood eosinophil counts remain in memory	33
Dimethyl itaconate selectively targets inflammatory and metabolic pathways in chronic lymphocytic leukemia	33
Epigenetic Regulation of CD8 ⁺ Effector T Cell Differentiation by PDCD5	32
Immunoregulation of asthma by type 2 cytokine therapies: Treatments for all ages?	32
Fate‐mapping studies in inbred mice: A model for understanding macrophage development and homeostasis?	32

Neutrophil subsets in noncancer liver diseases: Cellular crosstalk and therapeutic targets	31
Induction of Tolerogenic Dendritic Cells by a Noncoding Oligonucleotide	31
Intrahepatic plasma cells, but not atypical memory B cells, associate with clinical phases of chronic hepatitis B	30
Staphylococcus aureus ‐derived factors promote human Th9 cell polarization and enhance a transcriptional program associated with allergic inflammation	30
Metabolic dynamics instruct CD8 ⁺ T‐cell differentiation and functions	30
The Phenotypical and Functional Effect of PGE2 on Human Macrophages	29
Surface CD69‐Negative CD4 and CD8 Bone Marrow‐Resident Human Memory T Cells	29
Emerging roles of host and microbial bioactive lipids in inflammatory bowel diseases	29
Sustained innate interferon is an essential inducer of tertiary lymphoid structures	28
Mast cells in type 2 skin inflammation: Maintenance and function	27
Regulatory T cells as a therapeutic approach for inflammatory bowel disease	27
	26
Issue Information: Eur. J. Immunol. 1'25	25
In this issue	25
Cover Story: Eur. J. Immunol. 1'24	25
Communication and transparency at EJI: Supporting authors through their publishing experience	24
Issue Information: Eur. J. Immunol. 8'23	24
Current research and unmet needs in allergy and immunology in Germany: report presented by the DGfI and DGAKI task force Allergy & Immunology	23
The Young Immunologists' Podcast: Immunology and Much More	23
	22
Potentiation of the axis involving pentose phosphate pathway/NADPH oxidase/reactive oxygen species drives higher IL‐10 production in monocytes of Sub‐Saharan Africans	22
LCMV induced downregulation of HVEM on antiviral T cells is critical for an efficient effector response	22
Functional Fc receptors are crucial in antibody‐mediated protection against cytomegalovirus	22
Key actors in neuropathophysiology: The role of γδ T cells	22
Czech Young Immunologists: Bound by science, united in purpose	22
Cytokine Autoantibodies Alter Gene Expression Profiles of Healthy Donors	21
TLR9‐Driven S‐Palmitoylation in Dendritic Cells Reveals Immune and Metabolic Protein Targets	21
IL‐4, IL‐15, and Type I Interferon Orchestrate the Shaping of the Heterogeneity of Virtual Memory CD8 T Cells	20
Mouse dendritic cells and other myeloid subtypes in healthy lymph nodes and skin: 26‐Color flow cytometry panel for immune phenotyping	20
Immunomodulation of neutrophil granulocyte functions by bacterial polyphosphates	20
Researcher Reflections—Inspiring Paths in Academia	20
IQGAP1 Influences Neutrophil Maturation and Its Effector Functions	20
Global k _off ‐rates of polyclonal T‐cell populations merge subclonal avidities and predict functionality	20
Immediate major dynamic changes in the T‐ and NK‐cell subset composition after cardiac transplantation	20
Fully functional monocytic MDSC generation from the murine HoxB8 cell line	20
Innate immunity champions: The diverse functions of macrophages	19
Paradoxical immunodeficiencies—When failures of innate immunity cause immunopathology	19
AK2‐Deficient Mice Recapitulate Impaired Lymphopoiesis of Reticular Dysgenesis Patients, but Also Lack Erythropoiesis	19
The VEGF‐Mediated Cytoprotective Ability of MIF‐Licensed Mesenchymal Stromal Cells in House Dust Mite‐Induced Epithelial Damage	19
YF17D‐based vaccines – standing on the shoulders of a giant	19
Enhanced in vitro type 1 conventional dendritic cell generation via the recruitment of hematopoietic stem cells and early progenitors by Kit ligand	19
Hyperinflammation by Human Macrophages Induced by SARS‐CoV‐2 Anti‐Spike IgG Is Dependent on Glucose and Fatty Acid Metabolism	18
Impressum	18
T‐cell signature cytokines distinguish pulmonary sarcoidosis from pulmonary tuberculosis	18
Novel homozygous CD46 variant with C‐isoform expression affects C3b inactivation in atypical hemolytic uremic syndrome	18
Mastering Immunity: Antibody Feedback as a Driver of Germinal Center Fate and Vaccine Responses	18
	18
In this issue	17
Journal roundup	17
EFIS News	17

In this issue	17
Contents: Eur. J. Immunol. 7'22	17
Immunology meeting	17
Contents: Eur. J. Immunol. 11'22	17
Impressum	17
Expanding our understanding of Guillain–Barré syndrome: Recent advances and clinical implications	16
Sex‐specific impact of psychosocial stress on hematopoiesis and blood leukocytes	16
Distinct Tissue‐Dependent Composition and Gene Expression of Human Fetal Innate Lymphoid Cells	16
	16
B Cell Receptor Repertoire Analysis of the CD21 ^lo B Cell Compartment in Healthy Individuals, Patients With Sjögren's Disease, and Patients With Radi	16
Microenvironmental signals shaping NK‐cell reactivity in cancer	16
Acquired immune resistance is associated with interferon signature and modulation of KLF6/c‐MYB transcription factors in myeloid leukemia	16
The Swiss Young Immunologists Society (SYIS): Empowering the next generation of immunologists	16
PP2A catalytic subunit alpha is critically required for CD8 ⁺ T‐cell homeostasis and antibacterial responses	16
	16
Human cDC1s display constitutive activation of the UPR sensor IRE1	16
Exploring How Cytoskeleton Dynamics Tunes T Cell Activation at the Immunological Synapse	16
Endogenous secretory leukocyte protease inhibitor inhibits microbial‐induced monocyte activation	16
The immunosuppressive drug cyclosporin A has an immunostimulatory function in CD8 ⁺ T cells	16
Knockout of SLy1 decreases double‐negative thymocyte proliferation and protects mice from p53‐induced tumor formation	15
MicroRNA‐146a deficiency enhances host protection against murine cytomegalovirus	15
Differential regulation of CD8 ⁺ CD86 ⁺ Vγ1.1 ⁺	15
Release of IL‐1β and IL‐18 in human primary bronchial epithelial cells exposed to cigarette smoke is independent of NLRP3	15
Issue Information: Eur. J. Immunol. 12'25	15
Dendritic cells generated from induced pluripotent stem cells and by direct reprogramming of somatic cells	15
Pamidronate‐Induced Clinical Remission in Chronic Non‐bacterial Osteomyelitis Is Associated with Reduced Vγ9Vδ2 T‐Cell Receptor Expression	15
Differential Runx3, Eomes, and T‐bet expression subdivides MS‐associated CD4 ⁺ T cells with brain‐homing capacity	15
Single‐cell multi‐omics analysis of COVID‐19 patients with pre‐existing autoimmune diseases shows aberrant immune responses to infection	15
Intestinal homeostasis and inflammation: Gut microbiota at the crossroads of pancreas–intestinal barrier axis	15
DsbA‐L deletion attenuates LPS‐induced acute kidney injury by modulating macrophage polarization	15
Tyrosine kinase inhibitor cabozantinib impacts dendritic and natural killer cells immune response in C38 syngeneic tumor model	15
Guidelines for mouse and human DC generation	15
Nonreplicating synthetic mRNA vaccines: A journey through the European (Journal of Immunology) history	15
Langerhans cells orchestrate apoptosis of DNA‐damaged keratinocytes upon high‐dose UVB skin exposure	15
	14
Methiothepin downregulates SNAP‐23 and inhibits degranulation of rat basophilic leukemia cells and mouse bone marrow‐derived mast cells	14
Cover Story: Eur. J. Immunol. 12'23	14
	14
Cover story: Eur. J. Immunol. 7'22	14
Lymphotoxins from distinct types of lymphoid cells differentially contribute to neuroinflammation	14
Correction	14
Proteomics reveals a global phenotypic shift of NK cells in HCV patients treated with direct‐acting antivirals	14
Issue Information: Eur. J. Immunol. 7'23	14
Diversity of regulatory B cells: Markers and functions	13
SARS‐CoV‐2‐specific T cells are generated in less than half of allogeneic HSCT recipients failing to seroconvert after COVID‐19 vaccination	13
From simple to complex: Protein‐based biomarker discovery in tuberculosis	13
Augmented neutralization of SARS‐CoV‐2 Omicron variant by boost vaccination and monoclonal antibodies	13
A human immune system (HIS) mouse model that dissociates roles for mouse and human FcR⁺ cells during antibody‐mediated immune responses	13
SIRPα: A key player in innate immunity	13
In this issue	13
Bin‐based visualization of cytokine‐co‐expression patterns of IL‐10‐producing CD4 T cell subsets	13
Georg Friedrich (Fritz) Melchers (27.4.1936–24.2.2025)	13
Therapeutic targeting of factor D and MASP3 in complement‐mediated diseases: Lessons learned from mouse studies	13
Interleukin‐2‐induced skin inflammation	13
Human T Cell Responses to Flavivirus Vaccines	13
Imaging Mass Cytometry‐Based Immune Profiling of Human Peyer's Patches in Patients with Crohn's Disease	13
Resolution of Autoimmune Uveitis Requires CCL20‐Dependent Regulatory T Cells	13
Booster Injection with Birch Pollen Extract Activates B‐Cellular Memory Responses in Patients Having Completed Allergen Immunotherapy	13
Actinin‐4 controls survival signaling in B cells by limiting the lateral mobility of B‐cell antigen receptors	13
Acellular Pertussis Vaccines Induce CD8 ⁺ and CD4 ⁺ Regulatory T Cells That Suppress Protective Ti	13
Epigenetic Regulations in Autoimmunity and Cancer: from Basic Science to Translational Medicine	12
Portuguese Society of Immunology (SPI): Turning 50, inspired by the past, looking into the future	12
TNF Production or TNFR2 Expression Characterize Distinct States of Regulatory T Cells that Cooperate in Treg Expansion in Cancer and Chronic Inflammation	12
Impressum	12
Inhibition of Melanoma Growth by Ex Vivo Expanded Tumor‐Specific CD8+ T Cells Is Dependent on the Configuration of Nanoscale Artificial APCs	12
CCR4 ⁺ CD8 ⁺ T cells clonally expand to differentiated effectors in murine psoriasis and in human	12
Effect of Aspirin Challenge on Innate Lymphoid Cells in Asthma Patients With Aspirin Hypersensitivity	12
Impressum	12
Regulation of B‐cell function and expression of CD11c, T‐bet, and FcRL5 in response to different activation signals	12
Characterization of human CD4 ⁺ EOMES ⁺ GzmK ⁺	12
Molecular and functional in vivo characterisation of murine Dectin‐1 isoforms	12
Impressum	11
Cover Story: Eur. J. Immunol. 8'23	11
	11
Puppet masters of B‐cell progenitor acute lymphoblastic leukemia: The preB cell receptor and the interleukin 7 receptor α	11
Detection of dendritic cell subsets in the tumor microenvironment by multiplex immunohistochemistry	11
	11
Front cover story: Eur. J. Immunol. 2'22	11
Cover Story: Eur. J. Immunol. 5'24	11
Specificity of mouse and human Fcgamma receptors and their polymorphic variants for IgG subclasses of different species	11

Antibiotic use during pregnancy is linked to offspring gut microbial dysbiosis, barrier disruption, and altered immunity along the gut–lung axis	11
	11
Issue Information: Eur. J. Immunol. 1'23	11
Impressum	11
PIEZO1‐mediated mechanosensing governs NK‐cell killing efficiency and infiltration in three‐dimensional matrices	11
TLR4 phosphorylation at tyrosine 672 activates the ERK/c‐FOS signaling module for LPS‐induced cytokine responses in macrophages	11
Contents: Eur. J. Immunol. 8'22	11
The first year of young group of the Spanish Immunology Society: Progress, challenges, and next steps	10
Baseline Single‐Cell Differences in Polyfunctionality Between Systemic Autoinflammatory Diseases Patients and Healthy Controls	10
Autoimmunity and SARS‐CoV‐2 infection: Unraveling the link in neurological disorders	10
TLR2 on CD4+ and CD8+ T cells promotes control of Mycobacterium tuberculosis infection	10
Retinoic acid‐loaded liposomes induce human mucosal CD103 ⁺ dendritic cells that inhibit Th17 cells and drive regulatory T‐cell development in vitro	10
High Extracellular K ⁺ Skews T‐Cell Differentiation Towards Tumour Promoting Th2 and T _reg Subsets	10
Interleukin 23 receptor: Expression and regulation in immune cells	10
Crafting an MSCA PhD Masterpiece: Guiding Students on the Verge of Discovery	10
Survival of Human Bone Marrow Plasma Cells In Vitro Depends on the Support of the Stromal Cells, PI3K, and Canonical NF‐kappaB Signaling	10
Chronic stimulation desensitizes β2‐adrenergic receptor responses in natural killer cells	10
Bystander activation of tissue‐resident memory CD4 T cells: Getting by with a little help from unfamiliar T‐cell friends	10
Effects of altered salt intake and diet on cytokines in humans: A 20‐week randomized cross‐over intervention study	10
Guidelines for DC preparation and flow cytometry analysis of mouse lymphohematopoietic tissues	10
Neural Crest‐Derived Mesenchymal Cells Support Thymic Reconstitution After Lethal Irradiation	10
Translational immunology: Applying fundamental discoveries to human health and autoimmune diseases	10
Vitamin A‐treated natural killer cells reduce interferon‐gamma production and support regulatory T‐cell differentiation	10
Immunogenicity‐Guided Design of an Acinetobacter baumanii Vaccine	10
	10
IL1R2 Acts as a Negative Regulator of Monocyte Recruitment During Inflammation	10
Multifaceted Role of ILCs in Metabolic Adaptations: From Adult to Neonate	9
Characteristics and mechanisms of T‐cell senescence: A potential target for cancer immunotherapy	9
Upregulation of IL4‐induced gene 1 enzyme by B2 cells during melanoma progression impairs their antitumor properties	9
Follicular helper T cell signature of replicative exhaustion, apoptosis, and senescence in common variable immunodeficiency	9
yEFIS with EFIS Lead the Way to ECR Engagement at ECI2024	9
Plasmodium berghei Radiation‐Attenuated Sporozoite‐Immunized Mice Require Infectious Sporozoite Challenge to Maintain Protective Immunity	9
Regulation of DC metabolism by nitric oxide in murine GM‐CSF cultures	9
Foxp3⁺ regulatory T cells in the central nervous system and other nonlymphoid tissues	9
Trametinib Suppresses the Stimulated T Cells Through G1 Arrest and Apoptosis	9
yEFIS 1^st Symposium: Shaping the future of Immunology in Europe, 10–11 November, 2022, Berlin, Germany	9
ICAP‐1 loss impairs CD8⁺ thymocyte development and leads to reduced marginal zone B cells in mice	9
Combined Deletion of ZFP36L1 and ZFP36L2 Drives Superior Cytokine Production in T Cells at the Cost of Cell Fitness	9
Zfp362 potentiates murine colonic inflammation by constraining Treg cell function rather than promoting Th17 cell differentiation	9
Dendritic cells Trigger IFN‐γ secretion by NK cells independent of IL‐12 and IL‐18	9
PD‐L2 Inhibits Protective Immunity, Th2 Cell Functional Quality, and GATA‐3 Expression During Filarial Nematode Infection	9
	9
In this issue	9
Cover Story: Eur. J. Immunol. 4'25	9
Prmt5 deficient mouse B cells display RNA processing complexity and slower colorectal tumor progression	9
Interferon α and β induce differential transcriptional and functional metabolic phenotypes in human macrophages and blunt glycolysis in response to antigenic stimuli	9
Autoantibodies targeting type I interferons: Prevalence, mechanisms of induction, and association with viral disease susceptibility	8
Therapeutic tactics for targeting B lymphocytes in autoimmunity and cancer	8
SARS‐CoV‐2 variants of concern elicit divergent early immune responses in hACE2 transgenic mice	8
	8
Verteporfin protects against Th17 cell‐mediated EAE independently of YAP inhibition	8
Cover Story: Eur. J. Immunol. 4'24	8
TOX Does Not Drive Sepsis‐Induced T‐Cell Exhaustion	8
MicroRNAs targeting TGF‐β signaling exacerbate central nervous system autoimmunity by disrupting regulatory T cell development and function	8
	8
Sphingosine‐1‐phosphate receptor type 4 is critically involved in the regulation of peritoneal B‐1 cell trafficking and distribution in vivo	8
Polymorphism in F pocket affects peptide selection and stability of type 1 diabetes‐associated HLA‐B39 allotypes	8
	8
FcµR and IgM‐Mediated Complement Activation Cooperate to Enhance Humoral Immunity	8
Immunity in malignant brain tumors: Tumor entities, role of immunotherapy, and specific contribution of myeloid cells to the brain tumor microenvironment	8
Meeting Report: German–Japanese Alliance in Immunology	8
PAD2 immunization induces ACPA in wild‐type and HLA‐DR4 humanized mice	8
Identification and Mapping of Human Lymph Node Stromal Cell Subsets by Combining Single‐Cell RNA Sequencing with Spatial Transcriptomics	8
Impact of the adenosine receptor A2BR expressed on myeloid cells on immune regulation during pregnancy	8
Cover Story: Eur. J. Immunol. 8'24	8
Antibody density on bacteria regulates C1q recruitment by monoclonal IgG but not IgM	8
Issue Information: Eur. J. Immunol. 5'25	8
Influence of SLAM Family Receptors in the NK‐Cell‐Mediated Surveillance of Lymphoblastic Acute Leukemia	8
T helper cell subsets: diversification of the field	8
GPR109A expressed on medullary thymic epithelial cells affects thymic Treg development	8
CD95L concatemers highlight different stoichiometries of CD95‐mediated apoptotic and nonapoptotic pathways	8
Deciphering the Human Germinal Center: A Review of Models to Study T–B Cell Interactions	8
Altered IgG glycosylation at COVID‐19 diagnosis predicts disease severity	8
The complement system: A key player in the host response to infections	8
Antigen‐Specific Tolerance: Clinical and Preclinical Approaches in Autoimmunity	8
Impressum	8
Composition of fatty acids in a high‐fat diet affects adipose tissue inflammation by inducing calreticulin on adipocytes and activating group 1 innate lymphoid cells	8
Cover Story: Eur. J. Immunol. 11'23	8
	8
Impressum	8
Fine needle aspiration of human lymph nodes reveals cell populations and soluble interactors pivotal to immunological priming	8
Sensing context: Inhibitory receptors on non‐hematopoietic cells	8
Rational design of polymer‐based particulate vaccine adjuvants	8
PBMC‐derived extracellular vesicles in a smoking‐related inflammatory disease model	7
NK Cell Immaturity and NKp30 Expression Positively Correlate with Clinical Outcome in Multiple Myeloma Patients from the IFM2009 Clinical Trial	7
Survival and Developmental Progression of Unselected Thymocytes in the Absence of the T‐Cell Adaptor Gads	7
Issue Information: Eur. J. Immunol. 11'24	7
Neutralizing antibodies to SARS‐CoV‐2 Omicron variant after third mRNA vaccination in health care workers and elderly subjects	7
Advances in experimental models of rheumatoid arthritis	7
	7
STAT6‐induced production of mucus and resistin‐like molecules in lung Club cells does not protect against helminth or influenza A virus infection	7
Training the microbiota to increase immune checkpoint blockade and to reduce toxicity	7
KIRA6 is an Effective and Versatile Mast Cell Inhibitor of IgE‐mediated Activation	7
VSIG4‐Expressing Macrophages Contribute to Antiparasitic and Antimetastatic Responses in the Peritoneal Cavity	7
Escalation of Germinal Center Responses in Chronic Litomosoides sigmodontis Filarial Infection	7