OOIR: Observatory of International Research

Papers

(The TQCC of European Journal of Immunology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Journal roundup	325
	116
Transglutaminase 2 affinity and enzyme‐substrate intermediate stability as determining factors for T‐cell responses to gluten peptides in celiac disease	73
Dimethyl itaconate selectively targets inflammatory and metabolic pathways in chronic lymphocytic leukemia	71
Impressum	70
Fate‐mapping studies in inbred mice: A model for understanding macrophage development and homeostasis?	70
Issue Information: Eur. J. Immunol. 10'21	69
Immunomodulation under the lens of real‐time in vivo imaging	63
Cover Story: Eur. J. Immunol. 4'23	55
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France	54
Impressum	53
Bead‐by‐bead normalization of single antigen assays: A necessary step for accurate detection of weak anti‐HLA antibodies	46
Inborn errors of immunity and immunodeficiencies: Antibody‐mediated pathology and autoimmunity as a consequence of impaired immune reactions	46
Termination of CD40L co‐stimulation promotes human B cell differentiation into antibody‐secreting cells	45
The potential of γδ CAR and TRuC T cells: An unearthed treasure	45
Epigenetic Regulation of CD8⁺ Effector T Cell Differentiation by PDCD5	42
Neutrophil subsets in noncancer liver diseases: Cellular crosstalk and therapeutic targets	42
A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS‐CoV‐2 infection model	41
Immune signature of patients with cardiovascular disease predicts increased risk for a severe course of COVID‐19	41
Airway epithelial type‐2 alarmin profiles: Blood eosinophil counts remain in memory	38
Integrin activation enables rapid detection of functional Vδ1⁺ and Vδ2⁺ γδ T cells	38
Emerging roles of host and microbial bioactive lipids in inflammatory bowel diseases	38
B‐cell modulation with anti‐CD79b antibodies ameliorates experimental autoimmune encephalitis in mice	36
Fluorochrome‐labeled inhibitors of caspase‐1 require membrane permeabilization to efficiently access caspase‐1 in macrophages	36
Mast cells in type 2 skin inflammation: Maintenance and function	36

Sustained innate interferon is an essential inducer of tertiary lymphoid structures	36
Staphylococcus aureus‐derived factors promote human Th9 cell polarization and enhance a transcriptional program associated with allergic inflammation	36
Intrahepatic plasma cells, but not atypical memory B cells, associate with clinical phases of chronic hepatitis B	31
In memoriam Martin Röllinghoff (1941–2022)	31
Four challenges to CAR T cells breaking the glass ceiling	30
Metabolic dynamics instruct CD8⁺ T‐cell differentiation and functions	29
Guidelines for mouse and human DC functional assays	29
Immunoregulation of asthma by type 2 cytokine therapies: Treatments for all ages?	29
Regulatory T cells as a therapeutic approach for inflammatory bowel disease	29
Back cover story: Eur. J. Immunol. 6'21	28
Surface CD69‐Negative CD4 and CD8 Bone Marrow‐Resident Human Memory T Cells	28
Immediate major dynamic changes in the T‐ and NK‐cell subset composition after cardiac transplantation	28
Linking Epitope‐Specific T‐Cell Receptors to IFNγ Secretion Using Nanovial Technology	28
	28
In this issue	27
Issue Information: Eur. J. Immunol. 1'25	27
Issue Information: Eur. J. Immunol. 8'23	27
E‐Cadherin restricts mast cell degranulation in mice	26
Current research and unmet needs in allergy and immunology in Germany: report presented by the DGfI and DGAKI task force Allergy & Immunology	26
Cover Story: Eur. J. Immunol. 1'24	26
Fully functional monocytic MDSC generation from the murine HoxB8 cell line	26
Paradoxical immunodeficiencies—When failures of innate immunity cause immunopathology	26
Abortive HIV‐1 RNA induces pro‐IL‐1β maturation via protein kinase PKR and inflammasome activation in humans	26
	25
Cytokine Autoantibodies Alter Gene Expression Profiles of Healthy Donors	25
Communication and transparency at EJI: Supporting authors through their publishing experience	25
Immunomodulation of neutrophil granulocyte functions by bacterial polyphosphates	24
MHC class I molecules co‐stimulate NK1.1 signaling and enhance Ca²⁺ flux in murine NK cells	24
T‐cell signature cytokines distinguish pulmonary sarcoidosis from pulmonary tuberculosis	24
LCMV induced downregulation of HVEM on antiviral T cells is critical for an efficient effector response	24
BOB.1/OBF.1 is required during B‐cell ontogeny for B‐cell differentiation and germinal center function	24
Enhanced in vitro type 1 conventional dendritic cell generation via the recruitment of hematopoietic stem cells and early progenitors by Kit ligand	24
Researcher Reflections—Inspiring Paths in Academia	24
Metabolic reprograming shapes neutrophil functions in severe COVID‐19	23
The Young Immunologists' Podcast: Immunology and Much More	23
Potentiation of the axis involving pentose phosphate pathway/NADPH oxidase/reactive oxygen species drives higher IL‐10 production in monocytes of Sub‐Saharan Africans	23
Czech Young Immunologists: Bound by science, united in purpose	22
Cereblon regulates NK cell cytotoxicity and migration via Rac1 activation	22
Mouse dendritic cells and other myeloid subtypes in healthy lymph nodes and skin: 26‐Color flow cytometry panel for immune phenotyping	21
Key actors in neuropathophysiology: The role of γδ T cells	21
IQGAP1 Influences Neutrophil Maturation and Its Effector Functions	21
The VEGF‐Mediated Cytoprotective Ability of MIF‐Licensed Mesenchymal Stromal Cells in House Dust Mite‐Induced Epithelial Damage	21
Global k_off‐rates of polyclonal T‐cell populations merge subclonal avidities and predict functionality	21
YF17D‐based vaccines – standing on the shoulders of a giant	20
Innate immunity champions: The diverse functions of macrophages	19
Functional Fc receptors are crucial in antibody‐mediated protection against cytomegalovirus	19
	19
Release of IL‐1β and IL‐18 in human primary bronchial epithelial cells exposed to cigarette smoke is independent of NLRP3	18
DsbA‐L deletion attenuates LPS‐induced acute kidney injury by modulating macrophage polarization	18
In this issue	18

Immunology meeting	18
Nonreplicating synthetic mRNA vaccines: A journey through the European (Journal of Immunology) history	17
B Cell Receptor Repertoire Analysis of the CD21^lo B Cell Compartment in Healthy Individuals, Patients With Sjögren's Disease, and Patients With Radiographic Axial Spondyloarthritis	17
Single‐cell multi‐omics analysis of COVID‐19 patients with pre‐existing autoimmune diseases shows aberrant immune responses to infection	17
Distinct Tissue‐Dependent Composition and Gene Expression of Human Fetal Innate Lymphoid Cells	17
Acquired immune resistance is associated with interferon signature and modulation of KLF6/c‐MYB transcription factors in myeloid leukemia	17
Langerhans cells orchestrate apoptosis of DNA‐damaged keratinocytes upon high‐dose UVB skin exposure	17
MicroRNA‐146a deficiency enhances host protection against murine cytomegalovirus	17
The Swiss Young Immunologists Society (SYIS): Empowering the next generation of immunologists	17
PP2A catalytic subunit alpha is critically required for CD8⁺ T‐cell homeostasis and antibacterial responses	16
Knockout of SLy1 decreases double‐negative thymocyte proliferation and protects mice from p53‐induced tumor formation	16
The immunosuppressive drug cyclosporin A has an immunostimulatory function in CD8⁺ T cells	16
Differential regulation of CD8⁺CD86⁺ Vγ1.1⁺ γδT cell responses in skin barrier tissue protection and homeostatic maintenance	16
Novel homozygous CD46 variant with C‐isoform expression affects C3b inactivation in atypical hemolytic uremic syndrome	15
In this issue	15
Dendritic cells generated from induced pluripotent stem cells and by direct reprogramming of somatic cells	15
Sex‐specific impact of psychosocial stress on hematopoiesis and blood leukocytes	15
Impressum	15
Contents: Eur. J. Immunol. 7'22	15
	15
	15
Tyrosine kinase inhibitor cabozantinib impacts dendritic and natural killer cells immune response in C38 syngeneic tumor model	15
Contents: Eur. J. Immunol. 11'22	15
Contents: Eur. J. Immunol. 12'21	15
EFIS News	15
Journal roundup	15
Hyperlipidemia‐induced metabolic changes in regulatory T cells result in altered function	14
Impressum	14
Expanding our understanding of Guillain–Barré syndrome: Recent advances and clinical implications	14
Guidelines for mouse and human DC generation	13
Cover Story: Eur. J. Immunol. 12'23	13
Pamidronate‐Induced Clinical Remission in Chronic Non‐bacterial Osteomyelitis Is Associated with Reduced Vγ9Vδ2 T‐Cell Receptor Expression	13
Intestinal homeostasis and inflammation: Gut microbiota at the crossroads of pancreas–intestinal barrier axis	13
Helios is a marker, not a driver, of human Treg stability	13
Issue Information: Eur. J. Immunol. 7'23	13
Cover story: Eur. J. Immunol. 7'22	13
Human cDC1s display constitutive activation of the UPR sensor IRE1	13
Differential Runx3, Eomes, and T‐bet expression subdivides MS‐associated CD4⁺ T cells with brain‐homing capacity	13
Microenvironmental signals shaping NK‐cell reactivity in cancer	13
	13
Altered increase in STAT1 expression and phosphorylation in severe COVID‐19	13
Endogenous secretory leukocyte protease inhibitor inhibits microbial‐induced monocyte activation	13
Methiothepin downregulates SNAP‐23 and inhibits degranulation of rat basophilic leukemia cells and mouse bone marrow‐derived mast cells	12
Therapeutic targeting of factor D and MASP3 in complement‐mediated diseases: Lessons learned from mouse studies	12
	12
Bin‐based visualization of cytokine‐co‐expression patterns of IL‐10‐producing CD4 T cell subsets	12
Diversity of regulatory B cells: Markers and functions	12
Back cover story: Eur. J. Immunol. 7'21	12
Actinin‐4 controls survival signaling in B cells by limiting the lateral mobility of B‐cell antigen receptors	12
A human immune system (HIS) mouse model that dissociates roles for mouse and human FcR⁺ cells during antibody‐mediated immune responses	12
Lymphotoxins from distinct types of lymphoid cells differentially contribute to neuroinflammation	12
Augmented neutralization of SARS‐CoV‐2 Omicron variant by boost vaccination and monoclonal antibodies	12
Proteomics reveals a global phenotypic shift of NK cells in HCV patients treated with direct‐acting antivirals	12
Mutant B2M‐HLA‐E and B2M‐HLA‐G fusion proteins protects universal chimeric antigen receptor‐modified T cells from allogeneic NK cell‐mediated lysis	12
Contents: Eur. J. Immunol. 7'21	12
From simple to complex: Protein‐based biomarker discovery in tuberculosis	12
Correction	12
ACKR1 favors transcellular over paracellular T‐cell diapedesis across the blood‐brain barrier in neuroinflammation in vitro	12
Interleukin‐2‐induced skin inflammation	12
SIRPα: A key player in innate immunity	12
Anca Catrina 1971–2021	12
SARS‐CoV‐2‐specific T cells are generated in less than half of allogeneic HSCT recipients failing to seroconvert after COVID‐19 vaccination	12
TLR4 phosphorylation at tyrosine 672 activates the ERK/c‐FOS signaling module for LPS‐induced cytokine responses in macrophages	11
Portuguese Society of Immunology (SPI): Turning 50, inspired by the past, looking into the future	11
Impressum	11
Non‐zero‐sum microbiome immune system interactions	11
CCR4⁺CD8⁺ T cells clonally expand to differentiated effectors in murine psoriasis and in human psoriatic arthritis	11
Antibiotic use during pregnancy is linked to offspring gut microbial dysbiosis, barrier disruption, and altered immunity along the gut–lung axis	11
Epigenetic Regulations in Autoimmunity and Cancer: from Basic Science to Translational Medicine	11
Detection of dendritic cell subsets in the tumor microenvironment by multiplex immunohistochemistry	11
In this issue	11
Impressum	11
Deletion of TLR2⁺ erythro‐myeloid progenitors leads to embryonic lethality in mice	11
Puppet masters of B‐cell progenitor acute lymphoblastic leukemia: The preB cell receptor and the interleukin 7 receptor α	11
Regulation of B‐cell function and expression of CD11c, T‐bet, and FcRL5 in response to different activation signals	11
Characterization of human CD4⁺EOMES⁺GzmK⁺ T‐cell subsets unveils an uncoupling of suppressive functions from IL‐10‐producing capacities	11
PIEZO1‐mediated mechanosensing governs NK‐cell killing efficiency and infiltration in three‐dimensional matrices	11
Molecular and functional in vivo characterisation of murine Dectin‐1 isoforms	11
Bruton's tyrosine kinase inhibition induces rewiring of proximal and distal B‐cell receptor signaling in mice	11
Characterization of SARS‐CoV‐2 and common cold coronavirus‐specific T‐cell responses in MIS‐C and Kawasaki disease children	11

PDGFRα‐lineage origin directs monocytes to trafficking proficiency to support peripheral immunity	11
Specificity of mouse and human Fcgamma receptors and their polymorphic variants for IgG subclasses of different species	11
Compartmentalized multicellular crosstalk in lymph nodes coordinates the generation of potent cellular and humoral immune responses	10
Contents: Eur. J. Immunol. 8'22	10
Front cover story: Eur. J. Immunol. 2'22	10
	10
Impressum	10
Crafting an MSCA PhD Masterpiece: Guiding Students on the Verge of Discovery	10
Cover Story: Eur. J. Immunol. 8'23	10
TLR2 on CD4+ and CD8+ T cells promotes control of Mycobacterium tuberculosis infection	10
Impressum	10
Survival of Human Bone Marrow Plasma Cells In Vitro Depends on the Support of the Stromal Cells, PI3K, and Canonical NF‐kappaB Signaling	10
Inhibition of Melanoma Growth by Ex Vivo Expanded Tumor‐Specific CD8+ T Cells Is Dependent on the Configuration of Nanoscale Artificial APCs	10
Cover Story: Eur. J. Immunol. 5'24	10
Issue Information: Eur. J. Immunol. 1'23	10
Chronic stimulation desensitizes β2‐adrenergic receptor responses in natural killer cells	9
Upregulation of IL4‐induced gene 1 enzyme by B2 cells during melanoma progression impairs their antitumor properties	9
Interleukin 23 receptor: Expression and regulation in immune cells	9
The first year of young group of the Spanish Immunology Society: Progress, challenges, and next steps	9
Vitamin A‐treated natural killer cells reduce interferon‐gamma production and support regulatory T‐cell differentiation	9
High Extracellular K⁺ Skews T‐Cell Differentiation Towards Tumour Promoting Th2 and T_reg Subsets	9
Effects of altered salt intake and diet on cytokines in humans: A 20‐week randomized cross‐over intervention study	9
	9
Neural Crest‐Derived Mesenchymal Cells Support Thymic Reconstitution After Lethal Irradiation	9
Guidelines for DC preparation and flow cytometry analysis of mouse lymphohematopoietic tissues	9
	9
	9
Retinoic acid‐loaded liposomes induce human mucosal CD103⁺ dendritic cells that inhibit Th17 cells and drive regulatory T‐cell development in vitro	9
Translational immunology: Applying fundamental discoveries to human health and autoimmune diseases	9
Autoimmunity and SARS‐CoV‐2 infection: Unraveling the link in neurological disorders	9
Bystander activation of tissue‐resident memory CD4 T cells: Getting by with a little help from unfamiliar T‐cell friends	9
	9
IL1R2 Acts as a Negative Regulator of Monocyte Recruitment During Inflammation	9
Prmt5 deficient mouse B cells display RNA processing complexity and slower colorectal tumor progression	8
Regulation of DC metabolism by nitric oxide in murine GM‐CSF cultures	8
yEFIS 1^st Symposium: Shaping the future of Immunology in Europe, 10–11 November, 2022, Berlin, Germany	8
Trametinib Suppresses the Stimulated T Cells Through G1 Arrest and Apoptosis	8
Plasmodium berghei Radiation‐Attenuated Sporozoite‐Immunized Mice Require Infectious Sporozoite Challenge to Maintain Protective Immunity	8
Cover Story: Eur. J. Immunol. 8'24	8
Cover Story: Eur. J. Immunol. 11'23	8
Combined Deletion of ZFP36L1 and ZFP36L2 Drives Superior Cytokine Production in T Cells at the Cost of Cell Fitness	8
T helper cell subsets: diversification of the field	8
Fine needle aspiration of human lymph nodes reveals cell populations and soluble interactors pivotal to immunological priming	8
ICAP‐1 loss impairs CD8⁺ thymocyte development and leads to reduced marginal zone B cells in mice	8
	8
6^th European Congress of Immunology, 1–4 September 2021, Virtual meeting	8
Cover Story: Eur. J. Immunol. 4'25	8
Immunity in malignant brain tumors: Tumor entities, role of immunotherapy, and specific contribution of myeloid cells to the brain tumor microenvironment	8
	8
Cover Story: Eur. J. Immunol. 4'24	8
	8
yEFIS with EFIS Lead the Way to ECR Engagement at ECI2024	8
Polymorphism in F pocket affects peptide selection and stability of type 1 diabetes‐associated HLA‐B39 allotypes	8
Zfp362 potentiates murine colonic inflammation by constraining Treg cell function rather than promoting Th17 cell differentiation	8
Follicular helper T cell signature of replicative exhaustion, apoptosis, and senescence in common variable immunodeficiency	8
In this issue	8
Dendritic cells Trigger IFN‐γ secretion by NK cells independent of IL‐12 and IL‐18	8
Foxp3⁺ regulatory T cells in the central nervous system and other nonlymphoid tissues	8
Altered IgG glycosylation at COVID‐19 diagnosis predicts disease severity	8
Impressum	8
Antibody density on bacteria regulates C1q recruitment by monoclonal IgG but not IgM	8
Characteristics and mechanisms of T‐cell senescence: A potential target for cancer immunotherapy	8
Impressum	8
Interferon α and β induce differential transcriptional and functional metabolic phenotypes in human macrophages and blunt glycolysis in response to antigenic stimuli	8
The complement system: A key player in the host response to infections	7
MicroRNAs targeting TGF‐β signaling exacerbate central nervous system autoimmunity by disrupting regulatory T cell development and function	7
CD95L concatemers highlight different stoichiometries of CD95‐mediated apoptotic and nonapoptotic pathways	7
Composition of fatty acids in a high‐fat diet affects adipose tissue inflammation by inducing calreticulin on adipocytes and activating group 1 innate lymphoid cells	7
Issue Information: Eur. J. Immunol. 5'25	7
Issue Information: Eur. J. Immunol. 11'24	7
	7
Impressum	7
Issue Information: Eur. J. Immunol. 6'23	7
	7
Impact of the adenosine receptor A2BR expressed on myeloid cells on immune regulation during pregnancy	7
Verteporfin protects against Th17 cell‐mediated EAE independently of YAP inhibition	7
Rational design of polymer‐based particulate vaccine adjuvants	7
SARS‐CoV‐2 variants of concern elicit divergent early immune responses in hACE2 transgenic mice	7
Autoantibodies targeting type I interferons: Prevalence, mechanisms of induction, and association with viral disease susceptibility	7
Cover Story: Eur. J. Immunol. 3'23	7
In this issue	7
Early career immunology: A digital space to support early career investigators	7
	7
Dynamics of IL‐15/IL‐15R‐α expression in response to HSV‐1 infection reveal a novel mode of viral immune evasion counteracted by iNKT cells	7
TOX Does Not Drive Sepsis‐Induced T‐Cell Exhaustion	7
PAD2 immunization induces ACPA in wild‐type and HLA‐DR4 humanized mice	7
GPR109A expressed on medullary thymic epithelial cells affects thymic Treg development	7
Deciphering the Human Germinal Center: A Review of Models to Study T–B Cell Interactions	7
Ex vivo microRNA and gene expression profiling of human Tr1‐like cells suggests a role for miR‐92a and ‐125a in the regulation of EOMES and IL‐10R	7
Neutralizing antibodies to SARS‐CoV‐2 Omicron variant after third mRNA vaccination in health care workers and elderly subjects	7
Contents: Eur. J. Immunol. 1'22	7
Front cover story: Eur. J. Immunol. 11'22	7
	7
Sensing context: Inhibitory receptors on non‐hematopoietic cells	7
Sphingosine‐1‐phosphate receptor type 4 is critically involved in the regulation of peritoneal B‐1 cell trafficking and distribution in vivo	7