OOIR: Observatory of International Research

Papers

(The TQCC of European Journal of Immunology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
	308
Blockade of OX40/OX40L signaling using anti‐OX40L alleviates murine lupus nephritis	114
ThymoSpheres culture: A model to study human polyclonal unconventional T cells	101
Sustained innate interferon is an essential inducer of tertiary lymphoid structures	73
2024 German Society for Immunology Prizes	71
Immunization with excretory‐secretory molecules of intestinal nematodes induces antigen‐specific protective memory Th2 cell responses	71
TSLP and TSLPr Expression and Localization in the Airways of COPD and Non‐COPD Patients	69
HCMV Variants Expressing ULBP2 Enhance the Function of Human NK Cells via its Receptor NKG2D	67
Dual Activation‐Induced Marker Combinations Efficiently Identify and Discern Antigen‐Specific and Bystander‐Activated Human CD4⁺ T Cells	64
Trametinib Suppresses the Stimulated T Cells Through G1 Arrest and Apoptosis	60
Human Genetic GLUT1 Deficiency Results in Impaired T Cellular IFN‐γ Production	57
BAFF Blockade Attenuates B Cell MALT Formation in Conditional Nlrc5‐Deficient Mice With Helicobacter felis Infection	52
Ubiquitin‐Conjugating Enzyme Ubc13 in Macrophages Suppresses Lung Tumor Progression Through Inhibiting PD‐L1 Expression	51
T‐cell memory in tissues	48
Four challenges to CAR T cells breaking the glass ceiling	47
Issue Information: Eur. J. Immunol. 6'22	45
In this issue	44
2022 International Women's Day ‐ yEFIS highlights outstanding women vaccine researchers	42
Front cover story: Eur. J. Immunol. 4'22	40
Journal roundup	40
ICAP‐1 loss impairs CD8⁺ thymocyte development and leads to reduced marginal zone B cells in mice	39
Back cover story: Eur. J. Immunol. 4'22	39
Lung epithelial cells: Upstream targets in type 2‐high asthma	37
Impressum	37
	37

Front cover story: Eur. J. Immunol. 12'21	36
Our latest edition of Flow Cytometry Guidelines for basic and clinical immunologists!	35
Impressum	35
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	34
Characterizing dynamic tumor–immune interactions in lung adenocarcinoma through orthotopic allograft modeling	33
Pro‐ and antitumorigenic functions of γδ T cells	33
Rise of a CD27⁻ IgD⁻ CD11c⁺ B cells population in kidney recipients achieving long‐term graft stability under immunosuppression	33
Atg16l2 augments Nlrc4 inflammasome activation by facilitating NAIPs–NLRC4 association	32
Characteristics and mechanisms of T‐cell senescence: A potential target for cancer immunotherapy	31
Bead‐by‐bead normalization of single antigen assays: A necessary step for accurate detection of weak anti‐HLA antibodies	30
The potential of γδ CAR and TRuC T cells: An unearthed treasure	30
Immune signature of patients with cardiovascular disease predicts increased risk for a severe course of COVID‐19	30
Impact of antiretroviral therapy during primary HIV infection on T‐cell immunity after treatment interruption	30
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Epithelial–immune cell interactions in allergic diseases	28
Issue Information: Eur. J. Immunol. 3'24	27
Cover Story: Eur. J. Immunol. 2'24	26
Underrepresentation of activating KIR gene expression in single‐cell RNA‐seq data is due to KIR gene misassignment	26
Maturation signatures of conventional dendritic cell subtypes in COVID‐19 suggest direct viral sensing	25
Comprehensive analysis of T‐cell receptor repertoires reveals antigen‐driven T‐cell clusters in patients with Behçet's syndrome	25
Half a century of immunological discovery: EJI celebrates its golden anniversary!	25
In memoriam Martin Röllinghoff (1941–2022)	25
Impressum	24
	24
Journal roundup	24
Young EFIS: Three years of progress – Reflecting on achievements and embracing new horizons	23
Journal roundup	23
Impressum	23
	23
Journal Round	22
Agonistic anti‐CD27 antibody ameliorates EAE by suppressing IL‐17 production	22
Back cover story: Eur. J. Immunol. 10'21	22
Issue Information: Eur. J. Immunol. 10'21	22
EFIS and IUIS 2022 #DayofImmunology campaign	22
Regulation of autoimmune‐mediated neuroinflammation by endothelial cells	21
Impressum	21
Frequency of natural regulatory T cells specific for factor VIII in the peripheral blood of healthy donors	21
Impressum	21
A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS‐CoV‐2 infection model	20
RAG1/2 induces double‐stranded DNA breaks at non‐Ig loci in the proximity of single sequence repeats in developing B cells	20
Back cover story: Eur. J. Immunol. 4'21	20
A surrogate cell‐based SARS‐CoV‐2 spike blocking assay	20
Issue Information: Eur. J. Immunol. 3'22	20
Front cover story: Eur. J. Immunol. 3'22	20
IL‐27 mediates anti‐inflammatory effect in cigarette smoke induced emphysema by negatively regulating IFN‐γ producing cytotoxic CD8⁺T cells in mice	19
Dendritic cells Trigger IFN‐γ secretion by NK cells independent of IL‐12 and IL‐18	19
Peripheral differentiation patterns of human T cells	18
Point mutation L116R in interferon‐regulatory factor 4 differentially impacts key cytokine production in Th2, Th9, and Th17 cells	18
Vγ6⁺ γδ T cells are critical for protection against infection by Escherichia coli in mice	18

Prmt5 deficient mouse B cells display RNA processing complexity and slower colorectal tumor progression	18
Inborn errors of immunity and immunodeficiencies: Antibody‐mediated pathology and autoimmunity as a consequence of impaired immune reactions	18
Glycolytic metabolite phosphoenolpyruvate protects host from viral infection through promoting AATK expression	17
Sepsis shapes the human γδ TCR repertoire in an age‐ and pathogen‐dependent manner	17
Regulation of DC metabolism by nitric oxide in murine GM‐CSF cultures	17
cIAP1/2 antagonization by SMAC mimetic induces non‐canonical NF‐κB mediated T_H17 cell homotypic interactions and increases their resistance to shear stress	17
The EFIS vaccination task force expert report	16
T‐cell selection in the thymus: New routes toward the identification of the self‐peptide ligandome presented by thymic epithelial cells	16
Small molecule inhibitors targeting regulatory T cells for cancer treatment	16
Zfp362 potentiates murine colonic inflammation by constraining Treg cell function rather than promoting Th17 cell differentiation	16
B‐cell modulation with anti‐CD79b antibodies ameliorates experimental autoimmune encephalitis in mice	16
Monocytes promote UV‐induced epidermal carcinogenesis	16
16^th ENII‐EFIS‐EJI Summer School on Advanced Immunology	16
Antibodies internalization mechanisms by dendritic cells and their role in therapeutic antibody immunogenicity	16
Journal roundup	15
Transglutaminase 2 affinity and enzyme‐substrate intermediate stability as determining factors for T‐cell responses to gluten peptides in celiac disease	15
Young immunologists of Europe, unite ‐ and join us in Berlin!	15
Foxp3⁺ regulatory T cells in the central nervous system and other nonlymphoid tissues	15
Front cover story: Eur. J. Immunol. 6'21	15
Back cover story: Eur. J. Immunol. 9'22	15
A conserved pathway of transdifferentiation in murine Kupffer cells	14
Immunomodulatory activity of dipeptidyl peptidase‐4 inhibitors in immune‐related diseases	14
yEFIS 1^st Symposium: Shaping the future of Immunology in Europe, 10–11 November, 2022, Berlin, Germany	14
Impressum	14
Metabolic dynamics instruct CD8⁺ T‐cell differentiation and functions	14
Immunomodulation under the lens of real‐time in vivo imaging	14
Med1 controls thymic T‐cell migration into lymph node through enhancer‐based Foxo1‐Klf2 transcription program	14
COVID‐19 vaccines – common misperceptions, false claims and myths explained	14
Targeting Bcl6 in the TREX1 D18N murine model ameliorates autoimmunity by modulating T‐follicular helper cells and germinal center B cells	14
Peptidylprolyl isomerase C (Ppic) regulates invariant Natural Killer T cell (iNKT) differentiation in mice	14
Activation and differentiation of cognate T cells by a dextran‐based antigen‐presenting system for cancer immunotherapy	14
SLAMF7 selectively favors degranulation to promote cytotoxicity in human NK cells	13
Site‐specific serology unveils cross‐reactive monoclonal antibodies targeting influenza A hemagglutinin epitopes	13
Inhibition of tumor‐associated macrophages by trabectedin improves the antitumor adaptive immunity in response to anti‐PD‐1 therapy	13
Airway epithelial type‐2 alarmin profiles: Blood eosinophil counts remain in memory	13
Innate lymphoid cell characterization in the rat and their correlation to gut commensal microbes	13
Nanoparticles for stimulation of neutrophil extracellular trap‐mediated immunity	13
Renal medullary osmolytes NaCl and urea differentially modulate human tubular cell cytokine expression and monocyte recruitment	13
Successful treatment of COVID‐19 infection with convalescent plasma in B‐cell‐depleted patients may promote cellular immunity	13
Induction of the sphingosine‐1‐phosphate signaling pathway by TGF‐β1 during Langerhans‐type dendritic cell differentiation	13
Guidelines for mouse and human DC functional assays	13
Regulatory T cells and transplantation tolerance: Emerging from the darkness?	13
Staphylococcus aureus‐derived factors promote human Th9 cell polarization and enhance a transcriptional program associated with allergic inflammation	13
Cover Story: Eur. J. Immunol. 4'23	13
Increased circulating T follicular helper 13 subset correlates with high IgE levels in pediatric allergic asthma	12
Flow cytometry‐based high‐throughput RNAi screening for miRNAs regulating MHC class II HLA‐DR surface expression	12
Issue Information: Eur. J. Immunol. 6'24	12
Polypyrimidine tract binding protein 1 regulates the activation of mouse CD8 T cells	12
Assessing anti‐SARS‐CoV‐2 cellular immunity in 571 vaccines by using an IFN‐γ release assay	12
A novel cryopreservation and biobanking strategy to study lymphoid tissue stromal cells in human disease	12
Neutrophil subsets in noncancer liver diseases: Cellular crosstalk and therapeutic targets	12
Temporal associations of plasma levels of the secreted phospholipase A₂ family and mortality in severe COVID‐19	12
Systemic lupus erythematosus patients contain B‐cell receptor repertoires sensitive to immunosuppressive drugs	12
Profiling the specificity of clonally expanded plasma cells during chronic viral infection by single‐cell analysis	12
Fine needle aspiration of human lymph nodes reveals cell populations and soluble interactors pivotal to immunological priming	12
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France	12
Probing TCR Specificity Using Artificial In Vivo Diversification of CDR3 Regions	12
Colony morphotype governs innate and adaptive pulmonary immune responses to Mycobacterium abscessus infection in C3HeB/FeJ mice	11
SARS‐CoV‐2 infection induces thymic atrophy mediated by IFN‐γ in hACE2 transgenic mice	11
A single subcutaneous or intranasal immunization with adenovirus‐based SARS‐CoV‐2 vaccine induces robust humoral and cellular immune responses in mice	11
Issue Information: Eur. J. Immunol. 9'24	11
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Fate‐mapping studies in inbred mice: A model for understanding macrophage development and homeostasis?	11
Impressum	11
Integrin activation enables rapid detection of functional Vδ1⁺ and Vδ2⁺ γδ T cells	11
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Cover Story: Eur. J. Immunol. 7'24	11
IRF8 regulates efficacy of therapeutic anti‐CD20 monoclonal antibodies	11
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Distinct and dynamic activation profiles of circulating dendritic cells and monocytes in mild COVID‐19 and after yellow fever vaccination	10
Interferon α and β induce differential transcriptional and functional metabolic phenotypes in human macrophages and blunt glycolysis in response to antigenic stimuli	10
Ursodeoxycholic acid impairs liver‐infiltrating T‐cell chemotaxis through IFN‐γ and CX3CL1 production in primary biliary cholangitis	10
Mast cells in type 2 skin inflammation: Maintenance and function	10
Regulatory T cells as a therapeutic approach for inflammatory bowel disease	10
Longitudinal SARS‐CoV‐2 seroprevalence in Portugal and antibody maintenance 12 months after infection	10
Adenovirus vector and mRNA vaccines: Mechanisms regulating their immunogenicity	10
Measuring single‐cell protein secretion in immunology: Technologies, advances, and applications	10
The thioredoxin system: Balancing redox responses in immune cells and tumors	10
Dimethyl itaconate selectively targets inflammatory and metabolic pathways in chronic lymphocytic leukemia	10
Citrulline enteral administration markedly reduces immunosuppressive extrafollicular plasma cell differentiation in a preclinical model of sepsis	10

Mesenchymal stromal cells and their small extracellular vesicles in allergic diseases: From immunomodulation to therapy	10
Follicular helper T cell signature of replicative exhaustion, apoptosis, and senescence in common variable immunodeficiency	10
Intrahepatic plasma cells, but not atypical memory B cells, associate with clinical phases of chronic hepatitis B	10
P2X7 is expressed on human innate‐like T lymphocytes and mediates susceptibility to ATP‐induced cell death	10
6^th European Congress of Immunology, 1–4 September 2021, Virtual meeting	10
Fluorochrome‐labeled inhibitors of caspase‐1 require membrane permeabilization to efficiently access caspase‐1 in macrophages	10
NLRP3 inflammasome triggers interleukin‐37 release from human monocytes	10
French club of Young Immunologists: One year and counting	10
Polymorphism in F pocket affects peptide selection and stability of type 1 diabetes‐associated HLA‐B39 allotypes	10
Emerging roles of host and microbial bioactive lipids in inflammatory bowel diseases	10
Diet, commensal microbiota‐derived extracellular vesicles, and host immunity	10
Mesenchymal stromal cells‐derived small extracellular vesicles modulate DC function to suppress Th2 responses via IL‐10 in patients with allergic rhinitis	10
Ubiquitination network in the type I IFN‐induced antiviral signaling pathway	9
Emerging imaging and liquid biomarkers in multiple sclerosis	9
Protection against allergies: Microbes, immunity, and the farming effect	9
Gingival fibroblast activation by Porphyromonas gingivalis is driven by TLR2 and is independent of the LPS‐TLR4 axis	9
Liver type 1 innate lymphoid cells undergo apoptosis in murine models of macrophage activation syndrome and are dispensable for disease	9
Epigenetic Regulation of CD8⁺ Effector T Cell Differentiation by PDCD5	9
The IFN‐inducible GTPase IRGB10 regulates viral replication and inflammasome activation during influenza A virus infection in mice	9
CD4⁺CD57⁺ senescent T cells as promoters of systemic lupus erythematosus pathogenesis and the therapeutic potential of senolytic BCL‐2 inhibitor	9
Alterations of blood monocyte subset distribution and surface phenotype are linked to infection severity in COVID‐19 inpatients	9
HLA‐DRB1*15:01 is a co‐receptor for Epstein–Barr virus, linking genetic and environmental risk factors for multiple sclerosis	9
Termination of CD40L co‐stimulation promotes human B cell differentiation into antibody‐secreting cells	9
Duplicated TLRs Possess Sub‐ and Neo‐Functionalization to Broaden Their Ligand Recognition in Crucian Carp (Carassius auratus)	9
Natural killer cell‐mediated ADCC in SARS‐CoV‐2‐infected individuals and vaccine recipients	9
T helper cell subsets: diversification of the field	9
Mechanisms of exTreg induction	9
Immunoregulation of asthma by type 2 cytokine therapies: Treatments for all ages?	8
UNC93B1 curbs cytosolic DNA signaling by promoting STING degradation	8
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Association of vaccine‐specific regulatory T cells with reduced antibody response to repeated influenza vaccination	8
Ex vivo microRNA and gene expression profiling of human Tr1‐like cells suggests a role for miR‐92a and ‐125a in the regulation of EOMES and IL‐10R	8
Intestinal tissue‐resident memory T cells maintain distinct identity from circulating memory T cells after in vitro restimulation	8
SARS‐CoV‐2 variants of concern elicit divergent early immune responses in hACE2 transgenic mice	8
ILC1: Development, maturation, and transcriptional regulation	8
A fluorescent reporter model for the visualization and characterization of T_DC	8
Cover Story: Eur. J. Immunol. 9'23	8
Cryopreservation of mouse thymus depletes thymocytes but supports immune reconstitution on transplantation	8
The inhibitory receptor CD300a is essential for neutrophil‐mediated clearance of urinary tract infection in mice	8
Decoding the potential role of regulatory T cells in sepsis‐induced immunosuppression	8
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Colostrum IgA1 antibodies recognize antigens from Helicobacter pylori and prevent cytoskeletal changes in human epithelial cells	8
Levamisole suppresses activation and proliferation of human T cells by the induction of a p53‐dependent DNA damage response	8
Immunity in malignant brain tumors: Tumor entities, role of immunotherapy, and specific contribution of myeloid cells to the brain tumor microenvironment	8
Tolerogenic dendritic cells alleviate collagen‐induced arthritis by forming microchimerism and affecting the expression of immune checkpoint molecules	8
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Front cover story: Eur. J. Immunol. 5'22	8
Plasmodium vivax infection alters the peripheral immunoregulatory network of CD4 T follicular cells and B cells	7
COVID‐19‐specific metabolic imprint yields insights into multiorgan system perturbations	7
In this issue	7
	7
Researcher Reflections—Inspiring Paths in Academia	7
Contents: Eur. J. Immunol. 11'21	7
Impressum	7
Cover Story: Eur. J. Immunol. 6'23	7
Bystander activation of Bordetella pertussis‐induced nasal tissue‐resident memory CD4 T cells confers heterologous immunity to Klebsiella pneumoniae	7
In this issue	7
Homologous and heterologous serological response to the N‐terminal domain of SARS‐CoV‐2 in humans and mice	7
Deciphering the Human Germinal Center: A Review of Models to Study T–B Cell Interactions	7
Back cover story: Eur. J. Immunol. 6'21	7
Issue Information: Eur. J. Immunol. 8'23	7
In this issue	7
IQGAP1 Influences Neutrophil Maturation and Its Effector Functions	7
EFIS Board 2022 – 2024	7
The breathtaking world of human respiratory in vitro models: Investigating lung diseases and infections in 3D models, organoids, and lung‐on‐chip	7
TOX Does Not Drive Sepsis‐Induced T‐Cell Exhaustion	7
Antigen receptor‐engineered Tregs inhibit CNS autoimmunity in cell therapy using nonredundant immune mechanisms in mice	7
Rational design of polymer‐based particulate vaccine adjuvants	6
E‐Cadherin restricts mast cell degranulation in mice	6
Dynamics of IL‐15/IL‐15R‐α expression in response to HSV‐1 infection reveal a novel mode of viral immune evasion counteracted by iNKT cells	6
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Cytokine Autoantibodies Alter Gene Expression Profiles of Healthy Donors	6
The VEGF‐Mediated Cytoprotective Ability of MIF‐Licensed Mesenchymal Stromal Cells in House Dust Mite‐Induced Epithelial Damage	6
Single‐cell phenotyping of bacteria combined with deep sequencing for improved contextualization of microbiome analyses	6
Verteporfin protects against Th17 cell‐mediated EAE independently of YAP inhibition	6
Invariant natural killer T cells drive hepatic homeostasis in nonalcoholic fatty liver disease via sustained IL‐10 expression in CD170⁺ Kupffer cells	6
Antigen clearance at the peak of the primary immune response induces experimental autoimmune encephalomyelitis	6
Fusobacterium nucleatum infection activates the noncanonical inflammasome and exacerbates inflammatory response in DSS‐induced colitis	6
Issue Information: Eur. J. Immunol. 8'21	6
Impressum	6
Issue Information: Eur. J. Immunol. 3'23	6
Type I Interferon Drives a Cellular State Inert to TCR‐Stimulation and Could Impede Effective T‐Cell Differentiation in Cancer	6
Direct Inhibitory Effect of HTLV‐1‐Infected T Cells on the Production of Anti‐Ro/SS‐A Antibody by B Cells from Patients with Sjögren's Syndrome	6
SARS‐CoV‐2‐reactive T‐cell receptors isolated from convalescent COVID‐19 patients confer potent T‐cell effector function	6
Issue Information: Eur. J. Immunol. 1'25	6
Issue Information: Eur. J. Immunol. 5'21	6
Miodrag L. Lukic (1941–2023)	6
A population of naive‐like CD4⁺ T cells stably polarized to the T_H1 lineage	6
Regulatory T cell‐derived interleukin‐15 promotes the diversity of immunological memory	6
Issue Information: Eur. J. Immunol. 7'21	6
Alveolar epithelial cells shape lipopolysaccharide‐induced inflammatory responses and reprogramming of alveolar macrophages	6
PAD2 immunization induces ACPA in wild‐type and HLA‐DR4 humanized mice	6
Cover Story: Eur. J. Immunol. 11'23	6