OOIR: Observatory of International Research

Papers

(The H4-Index of European Journal of Pharmacology is 46. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Retraction notice to “Tanshinone IIA protects hypoxia-induced injury by preventing microRNA-28 up-regulation in PC-12 cells” [Eur. J. Pharmacol. 854 (2019) 265–271]	261
Natural phenylethanoid glycoside forsythoside A alleviates androgenetic alopecia by selectively inhibiting TRPV3 channels in mice	166
Role of 11β-hydroxysteroid dehydrogenase type 1 inhibition in the antiobesity effect of J2H-1702 on adipocytes and a high-fat diet-induced NASH model	122
TNF-alpha mediates airway hyperreactivity in silicotic mice: Effect of thalidomide treatment	111
Retinal pharmacodynamic and pharmacokinetic profile of cannabidiol in an in vivo model of retinal excitotoxicity	107
Students’ perspective on the Dutch National Pharmacotherapy Assessment, a national survey study among final-year medical students	98
Sodium Danshensu alleviates bone cancer pain by inhibiting the osteoclast differentiation and CGRP expression	96
Metformin reduces inflammatory nociception in mice through a serotonin-dependent mechanism	96
Sodium-glucose cotransporter 2 inhibitor empagliflozin enhances autophagy and reverses remodeling in hearts with large, old myocardial infarctions	91
Luteolin alleviates diabetic cardiac injury related to inhibiting SHP2/STAT3 pathway	87
Corrigendum to “Isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate protects lipopolysaccharide-induced acute lung injury in mice by attenuating pyroptosis” [Eur. J. Pharmacol. 5 (2023) 175545]	86
The pathogenesis of depression: Roles of connexin 43-based gap junctions and inflammation	84
The Risk of Propofol Infusion Syndrome on Epilepsy Patients :Insights from FAERS Data and Published Case Reports	83
Targeting beta-catenin signaling for prevention of colorectal cancer – Nutraceutical, drug, and dietary options	75
CT2-3 induces cell cycle arrest and apoptosis in rheumatoid arthritis fibroblast-like synoviocytes through regulating PI3K/AKT pathway	74
Theaflavine inhibits hepatic stellate cell activation by modulating the PKA/LKB1/AMPK/GSK3β cascade and subsequently enhancing Nrf2 signaling	73
Effects of sacubitril-valsartan on aging-related cardiac dysfunction	71
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11	71
Comprehensive characterization of fatty acid oxidation in triple-negative breast cancer: Focus on biological roles and drug modulation	67
MK886 ameliorates Alzheimer's disease by activating the PRKCI/AKT signaling pathway	63
Rostral ventromedial medulla astrocytes regulate chronic itch and anxiety-related behaviors	63
Matrine alleviates Staphylococcus aureus-induced acute lung injury in mice by inhibiting MLKL and NLRP3-mediated inflammatory activity	62
Interleukin-35 mRNA therapy for influenza virus-induced pneumonia in mice	61
Modulating mitochondrial dynamics preserves cognitive performance via ameliorating iron-mediated brain toxicity in iron-overload rats	59
GDF11 alleviates cardiac ischemia/reperfusion injury by suppressing the mtDNA damage-inflammatory response axis	59

Safety, tolerability and pharmacokinetic profile of the low-impact ampakine CX717 in young healthy male subjects and elderly healthy male and female subjects	56
“Sigma-1 receptor modulation by clemastine highlights its repurposing as neuroprotective agent against seizures and cognitive deficits in PTZ-kindled rats”	55
Caveolin-1 attenuates acetaminophen aggravated lipid accumulation in alcoholic fatty liver by activating mitophagy via the Pink-1/Parkin pathway	55
Glutamine alleviates intestinal injury in a murine burn sepsis model by maintaining intestinal intraepithelial lymphocyte homeostasis	55
Comprehensive analysis of MAPK genes in the prognosis, immune characteristics, and drug treatment of renal clear cell carcinoma using bioinformatic analysis and Mendelian randomization	54
1, 8-cineole protects against ISO-induced heart failure by inhibiting oxidative stress and ER stress in vitro and in vivo	52
Advancing health care via artificial intelligence: From concept to clinic	51
Cediranib ameliorates portal hypertensive syndrome via inhibition of VEGFR-2 signaling in cirrhotic rats	51
A geniposide-phospholipid complex ameliorates posthyperuricemia chronic kidney disease induced by inflammatory reactions and oxidative stress	51
Aging in chronic lung disease: Will anti-aging therapy be the key to the cure?	50
Propionate ameliorates diabetes-induced neurological dysfunction through regulating the PI3K/Akt/eNOS signaling pathway	50
Spinal dopaminergic D1-and D2-like receptors have a sex-dependent effect in an experimental model of fibromyalgia	50
Melanocortin receptor-4 mediates the anorectic effect induced by the nucleus tractus solitarius injection of glucagon-like Peptide-2 in fasted rats	50
Licochalcone A induces G2/M phase arrest and apoptosis via regulating p53 pathways in esophageal cancer: In-vitro and in-vivo study	49
Retraction notice to “Ginsenoside Rg3 inhibits growth and epithelial-mesenchymal transition of human oral squamous carcinoma cells by down-regulating miR-221” [Eur. J. Pharmacol. 853 (2019) 353–363]	48
Retraction notice to “Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute inflammation” [Eur. J. Pharmacol. 483 (1) (2004) 79–93]	47
Oridonin, a small molecule inhibitor of cancer stem cell with potent cytotoxicity and differentiation potential	47
Curcumin nicotinate increases LDL cholesterol uptake in hepatocytes through IDOL/LDL-R pathway regulation	46
Sis-25, a meroditerpenoid derivative with a cyclobutane scaffold, inhibits activated T cell proliferation by targeting GSK3β in vitro and in vivo	46
Crosstalk relationship between adiponectin receptors, PPAR-γ and α-adrenoceptors in renal vasculature of diabetic WKYs	46
Non-coding RNAs and exosomal ncRNAs in multiple myeloma: An emphasis on molecular pathways	46