European Journal of Pharmacology

Article	Citations
Editorial Board	228
Comprehensive characterization of fatty acid oxidation in triple-negative breast cancer: Focus on biological roles and drug modulation	153
Corrigendum to “Isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate protects lipopolysaccharide-induced acute lung injury in mice by attenuating pyroptosis” [Eur. J. Pharmacol. 5 (2023) 175545]	131
Suppression of hypoxia-induced CAV1 autophagic degradation enhances nanoalbumin-paclitaxel transcytosis and improves therapeutic activity in pancreatic cancer	128
Combining brief recall and ketamine treatment prevents stress-primed methamphetamine memory reinstatement via heightening mPFC GABA activity	128
Inhibiting PRMT1 protects against CoNV by regulating macrophages through the FGF2/PI3K/Akt pathway	116
Autophagic inhibitor ROC-325 ameliorates glomerulosclerosis and podocyte injury via inhibiting autophagic flux in experimental FSGS mice	109
Inhibition of TRPC3 channels suppresses seizure susceptibility in the genetically-epilepsy prone rats	92
TNF-alpha mediates airway hyperreactivity in silicotic mice: Effect of thalidomide treatment	90
Trametinib ameliorated Adriamycin-induced podocyte injury by inhibiting METTL3 modified m6A RCAN1 RNA methylation	87
Sitagliptin reduces cytokine-induced β-cell apoptosis in prediabetes: A six-month interventional study	85
Small molecule CGRP receptor antagonists for the preventive treatment of migraine: A review	83
Inverse agonism of lysophospholipids with cationic head groups at Gi-coupled receptor GPR82	83
Neuroprotective effect of Perillyl alcohol in sporadic Alzheimer's disease in rats	75
Novel combinatorial autophagy inhibition therapy for triple negative breast cancers	75
Phosphodiesterase-1 inhibitor modulates Ca2+ regulation in sirtuin 1-deficient mouse cardiomyocytes	73
Significance of NMDA receptor-targeting compounds in neuropsychological disorders: An in-depth review	70
Long non-coding RNA MALAT1 modulates myocardial ischemia-reperfusion injury through the PI3K/Akt/eNOS pathway by sponging miRNA-133a-3p to target IGF1R expression	70
Evodiamine impairs HIF1A histone lactylation to inhibit Sema3A-mediated angiogenesis and PD-L1 by inducing ferroptosis in prostate cancer	68
HSP90: A promising target for NSCLC treatments	68
Ginsenoside Rb1 promotes the activation of PPARα pathway via inhibiting FADD to ameliorate heart failure	66
Metformin alleviates glucolipotoxicity-induced pancreatic β cell ferroptosis through regulation of the GPX4/ACSL4 axis	60
Effects of oleanolic acid and ursolic acid on depression-like behaviors induced by maternal separation in mice	59
Preventive effects of (−) epicatechin on tachycardia, cardiac hypertrophy, and nuclear factor- κB inflammatory signaling pathway in isoproterenol-induced myocardial infarcted rats	57
Isorhynchophylline ameliorates the progression of osteoarthritis by inhibiting the NF-κB pathway	56

Dehydrocostuslactone attenuated oxygen and glucose deprivation/reperfusion-induced PC12 cell injury through inhibition of apoptosis and autophagy by activating the PI3K/AKT/mTOR pathway	56
Calycosin treats acute myocardial infarction via NLRP3 inflammasome: Bioinformatics, network pharmacology and experimental validation	56
Compound Z526 alleviates chemotherapy-induced cachectic muscle loss by ameliorating oxidative stress-driven protein metabolic imbalance and apoptosis	55
Melittin suppresses aerobic glycolysis by regulating HSF1/PDK3 to increase chemosensitivity of NSCLC	55
Optimizing dose selection for doxorubicin-induced cardiotoxicity in mice: A comprehensive analysis of single and multiple-dose regimens	54
Optimizing the structure of repurposed metformin can improve anti-cholinesterase and anti-amyloidogenic effects	53
The novel GLP-1 / GIP dual agonist DA3-CH is more effective than liraglutide in the MPTP mouse model of Parkinson's disease	53
Inhibition of inducible nitric oxide synthase (iNOS) alleviates thoracic aortic aneurysm by regulating mitochondrial dynamics	52
Extracellular vesicles as multiorgan crosstalk mediators in cardiovascular diseases: emerging biomarkers and therapeutic targets	52
Cyclin-dependent kinase 5 inhibitor attenuates lipopolysaccharide-induced neuroinflammation through metabolic reprogramming	52
Characterisation of bis(4-aminoquinoline)s as α1A adrenoceptor allosteric modulators	52
Effects of chronic mirabegron treatment on metabolic and cardiovascular parameters as well as on atherosclerotic lesions of WHHL rabbits with high-fructose high-fat diet-induced insulin resistance.	51
Editorial Board	51
Antagonizing interleukin-5 receptor ameliorates dextran sulfate sodium-induced experimental colitis in mice through reducing NLRP3 inflammasome activation	51
Molecular interplay between EIF4 family and circular RNAs in cancer: Mechanisms and therapeutics	51
Nitisinone attenuates cartilage degeneration and subchondral osteoclastogenesis in osteoarthritis and concomitantly inhibits the cGAS/STING/NF-κB pathway	51
GPR146 regulates pulmonary vascular remodeling by promoting pulmonary artery smooth muscle cell proliferation through 5-lipoxygenase	50
The antidiabetic drug teneligliptin induces vasodilation via activation of PKG, Kv channels, and SERCA pumps in aortic smooth muscle	50
Corrigendum to “Guggulsterone inhibits migration and invasion through proteasomal and lysosomal degradation in human glioblastoma cells” [Eur. J. Pharmacol. 938 (2023) 175411]	49
Inhibition of intraflagellar transport protein-88 promotes epithelial-to-mesenchymal transition and reduces cardiac remodeling post-myocardial infarction	48
Editorial Board	48
Eukaryotic elongation factor 2 kinase inhibitor, A484954 inhibits perivascular sympathetic nerve stimulation-induced vasoconstriction in isolated renal artery	47
Ginsenoside Rg1 promotes fetal hemoglobin production in vitro: A potential therapeutic avenue for β-thalassemia	47
3,3′-O-dimethylquercetin: A bi-functional vasodilator isolated from green propolis of the Caatinga Mimosa tenuiflora	47
RNAi in psoriasis: A melodic exploration of miRNA, shRNA, and amiRNA with a spotlight on siRNA	46
Phloretin and Enalapril co-administration ameliorates hyperglycemia mediated exacerbation of myocardial injury in rats	46
Protein detection and localization of the non-selective cation channel TRPC6 in the human heart	46
Toward precision dosing of linezolid in critical ill patients: efficiency and risk of thrombocytopenia analysis by population PKPD modeling and simulations	45
Validating the temporal performance of genetic biomarkers in an animal model of recurrence/ non-recurrence myocardial infarction persuades by bioinformatics tools	45
Arctiin attenuated NASH by inhibiting glycolysis and inflammation via FGFR2/CSF1R signaling	45
The mitochondria-gut microbiota crosstalk – A novel frontier in cardiovascular diseases	45
Role of 11β-hydroxysteroid dehydrogenase type 1 inhibition in the antiobesity effect of J2H-1702 on adipocytes and a high-fat diet-induced NASH model	45
Dihydromyricetin restores mucus hypersecretion in Air–Liquid interface cultures in COPD by targeting the SRC-MAPK signaling pathway	45
Ameliorative effect of GLP1 agonist on vascular calcification in normoglycemic aged rat aorta via miR34a/SIRT6/NRF2/HO-1 signalling pathway	43
Targeting eEF2K induces oxidative stress and sensitizes cancer cells to ferroptosis induction	43
Dopamine agonists versus levodopa monotherapy in early Parkinson's disease for the potential risks of motor complications: A network meta-analysis	42
Suppression of hippocampal GABAergic transmission impairs memory in rodent models of Alzheimer's disease	41
Integrating network pharmacology, transcriptomics, and molecular simulation to reveal the mechanism of tert-butylhydroquinone for treating diabetic retinopathy	41
Tenacissoside H repressed the progression of glioblastoma by inhibiting the PI3K/Akt/mTOR signaling pathway	41
Molecular mechanisms and emerging therapeutics in pulmonary fibrosis: A recent update	41
Corosolic acid attenuates platelet-derived growth factor signaling in macrophages and smooth muscle cells of pulmonary arterial hypertension	40
Corrigendum to “Comparison of clopidogrel monotherapy versus prolonged DAPT based on the GRACE score in patients with acute coronary syndromes at High Ischemic and Bleeding Risk: a subgroup analysis o	40
Advancing health care via artificial intelligence: From concept to clinic	40
Early sacubitril/valsartan therapy reduces ventricular remodeling and cardiac events in patients with acute anterior myocardial infarction	40
PI3K/mTOR dual-inhibition with VS-5584 enhances anti-leukemic efficacy of ponatinib in blasts and Ph-negative LSCs of chronic myeloid leukemia	40
Amorphous selenium nanodots alleviate non-alcoholic fatty liver disease via activating VEGF receptor 1 to further inhibit phosphorylation of JNK/p38 MAPK pathways	40
Ghrelin alleviates placental dysfunction by down-regulating NF-κB phosphorylation in LPS-induced rat model of preeclampsia	39
IL-1 receptor-associated kinase family proteins: An overview of their role in liver disease	39
Resveratrol ameliorates cognitive impairment with improvement of gut microbiota, inflammation, neurogenesis, and synaptic proteins in a mouse model of Gulf War Illness	39
Hesperetin ameliorates spinal cord injury in rats through suppressing apoptosis, oxidative stress and inflammatory response	39

Inclusion of the in-chain sulfur in 3-thiaCTU increases the efficiency of mitochondrial targeting and cell killing by anticancer aryl-urea fatty acids	39
Low-intensity pulsed ultrasound prevents angiotensin II-induced aortic smooth muscle cell phenotypic switch via hampering miR-17-5p and enhancing PPAR-γ	39
Molecular mechanism and therapeutic significance of dihydromyricetin in nonalcoholic fatty liver disease	38
Orofacial pain models induce impairment in spatial learning and working memory in rodents: A systematic review and meta-analysis	38
Hydrogen sulfide ameliorates hypertension and vascular dysfunction induced by insulin resistance in rats by reducing oxidative stress and activating eNOS	38
Small-molecule targeting PKM2 provides a molecular basis of lactylation-dependent fibroblast-like synoviocytes proliferation inhibition against rheumatoid arthritis	38
Cardiovascular protective properties of the natural product eugenol	38
Nanomedicine: A great boon for cardiac regenerative medicine	38
Vanin1 (VNN1) in chronic diseases: Future directions for targeted therapy	37
Deciphering TGF-β1's role in drug resistance and leveraging plant bioactives for cancer therapy	37
Protective effect of 5,6,7,8-Tetrahydroxyflavone on high altitude cerebral edema in rats	37
A comprehensive review of targeting RAF kinase in cancer	37
Efficacy of the neurotensin receptor 1 analog PD149163 in modulation of the kidney inflammation: Inhibition of the nuclear factor kappa β signaling pathway and oxidative stress in endotoxemic mice	37
Astragaloside IV mitigates cerebral ischaemia-reperfusion injury via inhibition of P62/Keap1/Nrf2 pathway-mediated ferroptosis	37
Risperidone impedes glutamate excitotoxicity in a valproic acid rat model of autism: Role of ADAR2 in AMPA GluA2 RNA editing	36
Editorial Board	36
Manzamine A: A promising marine-derived cancer therapeutic for multi-targeted interactions with E2F8, SIX1, AR, GSK-3β, and V-ATPase - A systematic review	36
Hypoxia activates GPR146 which participates in pulmonary vascular remodeling by promoting pyroptosis of pulmonary artery endothelial cells	35
Anti-cancer impact of Hypericin in B-CPAP cells: Extrinsic caspase dependent apoptosis induction and metastasis obstruction	35
Hepatitis B Virus X Protein promotes VWF-mediated HCC progression through ST8SIA6-AS1/miR-3150b-3p/ASCL1 axis	35
Protective effects of 5(S)-5-carboxystrictosidine on myocardial ischemia-reperfusion injury through activation of mitochondrial KATP channels	35
Corrigendum to “Protective effects of cortex fraxini coumarines against oxonate-induced hyperuricemia and renal dysfunction in mice” [Eur. J. Pharmacol. 666 (2011) 196–204]	35
Sustained AT1R stimulation induces upregulation of growth factors in human cardiac fibroblasts via Gαq/TGF-β/ERK signaling that influences myocyte hypertrophy	35
Editorial Board	35
Succinate level is increased and succinate dehydrogenase exerts forward and reverse catalytic activities in lipopolysaccharides-stimulated cardiac tissue: The protective role of dimethyl malonate	34
Effects of cannabinoid agonists and antagonists in male rats discriminating the synthetic cannabinoid AM2201	34
Alpha1B-adreneroceptor is involved in norepinephrine-induced pulmonary artery smooth muscle cell proliferation via p38 signaling	34
Anti-pancreatic lipase and anti-adipogenic effects of 5,7,3′,4′,5′-pentamethoxy and 6,2′,4′-trimethoxy flavone - An in vitro study	34
Effects of the serotonin 5-HT1B receptor agonist CP 94253 on the locomotor activity and body temperature of preweanling and adult male and female rats	34
LncRNAS—modulators of neurovascular units in diabetic retinopathy	34
Aucubin supplementation alleviate diabetes induced-disruption of blood-testis barrier and testicular damage via stabilizing cell junction integrity	34
Stabilization of mitochondrial function by chlorogenic acid protects against kainic acid-induced seizures and neuronal cell death in rats	33
Dankasterone A induces prostate cancer cell death by inducing oxidative stress	33
Repositioning of Montelukast to inhibit proliferation of mutated KRAS pancreatic cancer through a novel mechanism that interfere the binding between KRAS and GTP/GDP	33
Pregabalin can interact synergistically with Kv7 channel openers to exert antinociception in mice	33
Face validation and pharmacologic analysis of Sik3 mutant mouse as a possible model of idiopathic hypersomnia	33
Identification of novel SIRT1 up-regulators using a cell-based high-throughput screening assay	33
Research progress on the role of orphan receptor GPR139 in neuropsychiatric behaviours	33
Editorial Board	32
Transcription factor MEOX1 accelerates pulmonary fibrosis by regulating mitophagy and senescence	32
Ankrd1 regulates endogenous cardiac regeneration in mice by modulating cyclin D1	32
Pirfenidone improves voiding function by suppressing bladder fibrosis in underactive bladder rats	32
Mutation of valine 53 at the interface between extracellular and transmembrane domains of the β2 principal subunit affects the GABAA receptor gating	32
Targeting endothelial cells: A novel strategy for pulmonary fibrosis treatment	32
SAP30BP aggravates mitochondrial-related ferroptosis in diabetic cardiomyopathy by regulating MFN2-ACSL4 axis	32
Tryptanthrin impairs platelet function and thrombus formation by reducing Gp1bα expression	32
Trigeminal neuropathic pain reduces 50-kHz ultrasonic vocalizations in rats, which are restored by analgesic drugs	32
SGLT2 inhibitor dapagliflozin mitigates skeletal muscle pathology by modulating key proteins involved in glucose and ion homeostasis in an animal model of heart failure	31
Crosstalk between endothelial cells with a non-canonical EndoMT phenotype and cardiomyocytes/fibroblasts via IGFBP5 aggravates TAC-induced cardiac dysfunction	31
Tumoral EIF4EBP1 regulates the crosstalk between tumor-associated macrophages and tumor cells in MRTK	31
Biochanin A inhibits excitotoxicity-triggered ferroptosis in hippocampal neurons	31
Sodium houttuyfonate protects against cardiac injury by regulating cardiac energy metabolism in diabetic rats	31
Sodium nitrite induces tolerance in the mouse aorta: Involvement of the renin-angiotensin system, nitric oxide synthase, and reactive oxygen species	31
High-throughput screening of the natural STK11 agonist dauricine: A biphenylisoquinoline alkaloid exerting anti-NSCLC effects and reversing gefitinib resistance	31
Dopamine agonist pramipexole halts leflunomide nephrotoxicity: A dual strike on TLR4-Driven inflammation and PI3K/Akt suppression	31
Cycloheptylprodigiosin from marine bacterium Spartinivicinus ruber MCCC 1K03745T induces a novel form of cell death characterized by Golgi disruption and enhanced secretion of cathepsin D in non-small	31
Naproxen as a potential candidate for promoting rivastigmine anti-Alzheimer activity against aluminum chloride-prompted Alzheimer's-like disease in rats; neurogenesis and apoptosis modulation as a pos	31
Next generation Bruton's tyrosine kinase inhibitors – characterization of in vitro potency and selectivity	31
Teneligliptin, a DPP4 inhibitor protects dopaminergic neurons in PD models via inhibiting of oxidative stress and ferroptosis	31
Pirfenidone and nintedanib attenuates pulmonary artery endothelial and smooth muscle cells transformations induced by IL-11	30
LRP1 at the crossroads of Parkinson's and Alzheimer's: Divergent roles in α-synuclein and amyloid pathology	30
CRISPR/Cas9-based multiplex genome editing of BCL11A and HBG efficiently induces fetal hemoglobin expression	30
Astragalus polysaccharide attenuates bleomycin-induced pulmonary fibrosis by inhibiting TLR4/ NF-κB signaling pathway and regulating gut microbiota	30
Astragaloside IV protects against C/EBP homologous protein-mediated apoptosis in oxidized low-density lipoprotein-treated macrophages by promoting autophagy	29
Oncolytic viruses as emerging therapy against cancers including Oncovirus-induced cancers	29
Recent advancements in targeting the immune system to treat hypertension	29
Influence of adrenalectomy on the gut microbiome and MDMA-induced hyperthermia	29
Dihydrotanshinone I improves cardiac function by promoting lymphangiogenesis after myocardial ischemia-reperfusion injury	29
Antidepressant-like effect of sodium orthovanadate in a mouse model of chronic unpredictable mild stress	29
CYT997 induces apoptosis in hypertrophic scar fibroblasts and inhibits scar formation	29
Asperosaponin VI alleviates intervertebral disc degeneration by suppressing nucleus pulposus cell pyroptosis through modulation of the NF-κB/NLRP3 signaling pathway	29
Involvement of ferroptosis in eribulin-induced cytotoxicity in ovarian clear cell carcinoma	29
Genkwanin blocks the interaction between phosphorylated JNK and NFATc1 to promote osteogenic differentiation and collagen Ⅰ α1 production	29
Cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs); where do they stand in tumorigenesis and how they can change the face of cancer therapy?	29
Potential of Orlistat to induce apoptotic and antiangiogenic effects as well as inhibition of fatty acid synthesis in breast cancer cells	29
Potential role of remimazolam in alleviating bone cancer pain in mice via modulation of translocator protein in spinal astrocytes	28
Ginkgolide A alleviates cardiac remodeling in mice with myocardial infarction via binding to matrix metalloproteinase-9 to attenuate inflammation	28
Valdecoxib blocks rat TRPV2 channels	28
Targets, trials and tribulations in Alzheimer therapeutics	28
Lapatinib ditosylate rescues motor deficits in rotenone-intoxicated rats: Potential repurposing of anti-cancer drug as a disease-modifying agent in Parkinson's disease	28

Cancer chemotherapy resistance: Mechanisms and recent breakthrough in targeted drug delivery	28
The key roles of non-coding RNAs in the pathophysiology of hypertension	28
Transcription factor EB protects against endoplasmic reticulum stress in human coronary artery endothelial cells	28
Diazepam-induced locomotor sensitization and increased cell surface AMPA receptors: Involvement of GABAA α1 subunit	28
Effects of intranasal azithromycin on features of cigarette smoke-induced lung inflammation	28
PARPs in tumor immunology: Signal transduction and combination therapy for the future	28
Inhibition of CHIT1 as a novel therapeutic approach in idiopathic pulmonary fibrosis	28
Up-regulated ITGB4 promotes hepatocellular carcinoma metastasis by activating hypoxia-mediated glycolysis and cancer-associated fibroblasts	27
Comparative efficacy and acceptability of drug treatments for Parkinson’s disease with depression: A systematic review with network meta-analysis	27
A novel Toll-like receptor 7/8–specific antagonist E6742 ameliorates clinically relevant disease parameters in murine models of lupus	27
A BET inhibitor, NHWD-870, can downregulate dendritic cells maturation via the IRF7-mediated signaling pathway to ameliorate imiquimod-induced psoriasis-like murine skin inflammation	27
Sophoricoside ameliorates cerebral ischemia-reperfusion injury dependent on activating AMPK	27
Drug repurposing: An emerging strategy in alleviating skin cancer	27
Hypoxia-inducible factor-1: Regulatory mechanisms and drug therapy in myocardial infarction	27
Poncirin ameliorates cardiac ischemia-reperfusion injury by activating PI3K/AKT/PGC-1α signaling	27
Recent trends in diabetic wound healing with nanofibrous scaffolds	27
Demyelination in cuprizone mice is ameliorated by calycosin mediated through astrocyte Nrf2 signaling pathway	27
Ginsenoside Rd attenuates myocardial ischemia injury through improving mitochondrial biogenesis via WNT5A/Ca2+ pathways	26
Human umbilical cord-derived stem cell sheets improve left ventricular function in rat models of ischemic heart failure	26
Inhibition of abnormally activated HIF-1α-GLUT1/3-glycolysis pathway enhances the sensitivity of hepatocellular carcinoma to 5-caffeoylquinic acid and its derivatives	26
Kurarinone induced p53-independent G0/G1 cell cycle arrest by degradation of K-RAS via WDR76 in human colorectal cancer cells	26
Curcumin nicotinate decreases serum LDL cholesterol through LDL receptor-mediated mechanism	26
Alternative role of glucagon-like Peptide-1 receptor agonists in neurodegenerative diseases	26
Galangin ameliorates osteoarthritis progression by attenuating extracellular matrix degradation in chondrocytes via the activation of PRELP expression	25
PAI-1 siRNA-loaded biomimetic nanoparticles for ameliorating diminished ovarian reserve and inhibiting ovarian fibrosis	25
Tulipalin A suppressed the pro-inflammatory polarization of M1 macrophage and mitigated the acute lung injury in mice via interference DNA binding activity of NF-κB	25
Nonadditive transcriptional change analysis identifies regulators for ginsenoside Rg3 to alleviate synergistic cytokine production in TLR2/3 dual-stimulated macrophages	25
Imperatorin attenuates CCl4-induced cirrhosis and portal hypertension by improving vascular remodeling and profibrogenic pathways	25
LncRNA DANCR deficiency promotes high glucose-induced endothelial to mesenchymal transition in cardiac microvascular cells via the FoxO1/DDAH1/ADMA signaling pathway	25
Advanced dressings based on novel biological targets for diabetic wound healing: A review	25
GW501516 facilitated tumor immune escape by inhibiting phagocytosis	25
Inhibiting 5-HT2C receptor in the hippocampus rescues EphB2-dependent memory impairment in mice	25
Cuproptosis induced by curcumin interfering with proliferation and energy metabolism in colorectal cancer: 3D tumor model and computational simulations reveal curcumin inhibition of HSPD1 and CALCOCO2	25
Salidroside attenuates high altitude hypobaric hypoxia-induced brain injury in mice via inhibiting NF-κB/NLRP3 pathway	25
Metabolic reprogramming of glutamine involved in tumorigenesis, multidrug resistance and tumor immunity	25
Trilobatin alleviates non-alcoholic fatty liver disease in high-fat diet plus streptozotocin-induced diabetic mice by suppressing NLRP3 inflammasome activation	25
In vivo and In vitro Crosstalk Among CBD, Aβ, and endocannabinoid system enzymes and receptors	25
Investigation of the effects of losartan and captopril on rotenone-induced inflammation via TLR4/NLRP3 pathway: An integrative in vitro and in silico study	25
IGF2/IGF2R/Sting signaling as a therapeutic target in DSS-induced ulcerative colitis	24
Anticancer activity and metabolic alteration in colon and prostate cancer cells by novel moxifloxacin conjugates with fatty acids	24
Discovery of cinnamoyl–flavonoid hybrid derivatives as inhibitors of SARS-CoV-2 Mpro and anti-inflammatory agents: Experimental and in silico insights into their efficacy against lipopolysaccharide-in	24
Effects of 101BHG-D01, a novel M receptor antagonism, on allergic rhinitis in animal models and its mechanism	24
Synthesis of 2-(2-(4-thioxo-3H-1,2-dithiole-5-yl) phenoxy)ethyl)isoindole-1,3-thione, a novel hydrogen sulfide-releasing phthalimide hybrid, and evaluation of its activity in models of inflammatory pa	24
Complementary effects of dapagliflozin and lobeglitazone on metabolism in a diet-induced obese mouse model	24
New insights on the differential interaction of sulfiredoxin with members of the peroxiredoxin family revealed by protein-protein docking and experimental studies	24
Corrigendum to “Combination therapy with citalopram, bupropion, and lithium for the amelioration of the depressive-related effects induced by dexamethasone in male mice” [Eur. J. Pharmacol. 1002 (2025	24
Luteolin alleviates hyposalivation by upregulating AQP5 through binding to estrogen receptor β and potentiating the saliva secretion signaling pathway	24
A positive allosteric modulator of α7 nicotinic receptor reduces levodopa-induced dyskinesias in hemi-parkinsonian mice	24
Emerging therapeutic avenues in cardiac amyloidosis	24
Gabapentin attenuates cardiac remodeling after myocardial infarction by inhibiting M1 macrophage polarization through the peroxisome proliferator-activated receptor-γ pathway	24
Synthetic flavokawain analog (E)-1-(2′-hydroxy-4′,6′-dimethoxyphenyl)-3-(3-methoxy-4-(3-morpholinopropoxy)phenyl)prop-2-en-1-one (FK-morph) effectively regresses endometriotic implants in rats	24
Koumine alters immune barrier function by targeting TGFβ-mediated collagen deposition in gastric cancer	24
Development of a novel Poly (I:C)-induced murine model with accelerated lupus nephritis and examination of the therapeutic effects of mycophenolate mofetil and a cathepsin S inhibitor	24
Comparison of the effects of peficitinib and tofacitinib in the adjuvant-induced arthritis rat model	24
Editorial Board	23
Effects of proprotein convertase subtilisin-kexin type 9 inhibitors on inflammatory and hemostatic parameters in post myocardial infarction patients	23
Dehydrozingerone alleviates pulmonary fibrosis via inhibition of inflammation and epithelial-mesenchymal transition by regulating the Wnt/β-catenin pathway	23
Dose-dependent opposite effects of nortriptyline on affective-like behavior in adolescent rats: Comparison with adult rats	23
Editorial Board	23
Exploring the mechanism of α-Bisabolol in the treatment of psoriasis based on network pharmacology and experimental validation	23
Analysis of differences in dupilumab-associated adverse drug event signals between children and adults based on the FAERS database	23
Curcumol suppresses endothelial-to-mesenchymal transition via inhibiting the AKT/GSK3β signaling pathway and alleviates pulmonary arterial hypertension in rats	23
Mechanisms underlying the efficacy and limitation of dopa and tetrahydrobiopterin therapies for the deficiency of GTP cyclohydrolase 1 revealed in a novel mouse model	23
Desmopressin enhances random-pattern skin flap survival in rats: Possible role of vasopressin Type-1a and 2 receptors	23
Cyanidin-3-O-glucoside and its derivative vitisin A alleviate androgenetic alopecia by exerting anti-androgen effect and inhibiting dermal papilla cell apoptosis	23
Retraction notice to “Apoptotic cell death: A possible key event in mediating the in vitro anti-proliferative effect of a novel copper(II) complex, [Cu(4-Mecdoa) (phen)2] (phen = phenanthroline, 4-Mec	23
Repurposing old molecules for new indications: Defining pillars of success from lessons in the past	22
Purinergic ionotropic P2X7 and metabotropic glutamate mGlu5 receptors crosstalk influences pro-inflammatory conditions in microglia	22
Beyond chemotherapy: Exploring 5-FU resistance and stemness in colorectal cancer	22
Mendelian randomization analysis with the GEO database: Exploring the molecular mechanism underlying insulin therapy for perioperative neurocognitive disorders	22
The soluble guanylate cyclase (sGC) stimulator vericiguat inhibits platelet activation and thrombosis	22
Effects of decrease in Klotho protein expression on insulin signaling and levels of proteins related to brain energy metabolism	22
Editorial Board	22
Involvement of ObRb receptor, nitric oxide, and BKCa channel signaling pathways in leptin-induced relaxation of pregnant mouse uterus	22
Sappanone A ameliorated imiquimod-induced psoriasis-like dermatitis in BALB/c mice via suppressing Mmp8 expression and IL-17 signaling pathway	22
The role of kappa opioid receptors in immune system – An overview	22
LncRNA MEG3 reverses CCl4-induced liver fibrosis by targeting NLRC5	22
PARP-1 inhibitor alleviates cerebral ischemia/reperfusion injury by reducing PARylation of HK-1 and LDH in mice	22
BRD4 as a therapeutic target for atrial fibrosis and atrial fibrillation	22
Therapeutic effects of finerenone and exenatide on diabetes-induced heart failure: A combined approach targeting inflammation and oxidative stress	22
lncRNA BBOX1-AS1 silencing inhibits esophageal squamous cell cancer progression by promoting ferroptosis via miR-513a-3p/SLC7A11 axis	22
Silibinin eliminates mitochondrial ROS and restores autophagy through IL6ST/JAK2/STAT3 signaling pathway to protect cardiomyocytes from doxorubicin-induced injury	22
Simultaneous nanocarrier-mediated delivery of siRNAs and chemotherapeutic agents in cancer therapy and diagnosis: Recent advances	22
Protective effects of atorvastatin on testicular dysfunction and reduced sperm quality induced by high-fat diet in mice: The inhibitory mechanism of oxidative stress	22
A combination of peripherally restricted CB1 and CB2 cannabinoid receptor agonists reduces bladder afferent sensitisation in cystitis	22
Investigating the mechanism of ferroptosis induction by sappanone A in hepatocellular carcinoma: NRF2/xCT/GPX4 axis	22
JAK2/STAT3 as a new potential target to manage neurodegenerative diseases: An interactive review	22
Oleocanthalic acid improves MASH features via a NOX1-dependent mechanism	22
Molsidomine ameliorates DEXA-induced insulin resistance: Involvement of HMGB1/JAK1/STAT3 signaling pathway	22
Hinokitiol protects gastric injury from ethanol exposure via its iron sequestration capacity	22
Overexpressed mitogen-and stress-activated protein kinase 1 promotes the resistance of cytarabine in acute myeloid leukemia through brahma related gene 1-mediated upregulation of heme oxygenase-1	22
Functional studies and molecular dynamics reveal BPP-BrachyNH2-induced relaxation in male rat small mesenteric arteries via binding to argininosuccinate synthase	22
Comprehensive analysis of transcriptomics and metabolomics to illustrate the underlying mechanism of helenalin against hepatic fibrosis	22
The next frontier in multiple sclerosis therapies: Current advances and evolving targets	22
Modulation of SIRT6 related signaling pathways of p-AKT/mTOR and NRF2/HO-1 by memantine contributes to curbing the progression of tamoxifen/HFD-induced MASH in rats	21