FEBS Letters

Article	Citations
Art and Science break boundaries in The Garden of Earthly Delights	113
Front Cover	83
Front Cover	70
Molecular and mechanical mechanisms of animal cell abscission	50
Cordycepin generally inhibits growth factor signal transduction in a systems pharmacology study	48
Silica‐coated magnetic nanobeads in a flow enrichment target capture Halbach (FETCH) magnetic separation system for circulating tumor cell enrichment	46
Insight into the function of the Golgi membrane protein GOLM1 in cholangiocytes through interactomic analysis	46
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A two‐step mechanism for the binding of the HIV‐1 MPER epitope by the 10E8 antibody onto biosensor‐supported lipid bilayers	43
CRK and NCK adaptors may functionally overlap in zebrafish neurodevelopment, as indicated by common binding partners and overlapping expression patterns	41
Novel insights into autophagosome biogenesis revealed by cryo‐electron tomography	38
Artificial miRNAs derived from miR‐181 family members have potential in cancer therapy due to an altered spectrum of target mRNAs	37
miR‐4734 conditionally suppresses ER stress‐associated proinflammatory responses	36
The fatty acid synthase inhibitor C75 differentially affects the adipogenic differentiation of multipotent cells and preadipocytes	35
Skraban‐Deardorff intellectual disability syndrome‐associated mutations in WDR26 impair CTLH E3 complex assembly	35
The ubiquitin–proteasome system and autophagy mutually interact in neurotoxin‐induced dopaminergic cell death models of Parkinson's disease	34
Promiscuous activity of β‐carotene hydroxylase CrtZ on epoxycarotenoids leads to the formation of rare carotenoids with 6‐hydroxy‐3‐keto‐ε‐ends	33
Localization of the ubiquitin ligase Dma1 to the fission yeast contractile ring is modulated by phosphorylation	33
Mycobacterium tuberculosis low molecular weight T‐cell antigen Mtb8.4 has heme‐binding and fiber‐forming properties	33
Interdomain electron transfer in flavohaemoglobin from Candida norvegensis with antibiotic azole compounds	33
Heparin promotes rapid fibrillation of the basic parathyroid hormone at physiological pH	32
Mapping secondary substrate‐binding sites on the GH11 xylanase from Bacillus subtilis	31
ArabidopsisRAN GTPases are critical for mitosis during male and female gametogenesis	31
Microscopic modulation and analysis of islets of Langerhans in living zebrafish larvae	31
Valosin‐containing protein regulates the stability of fused in sarcoma granules in cells by changing ATP concentrations	31

Clinical and mechanistic insights into the roles of DDX41 in haematological malignancies	31
Cytochrome bd‐I from Escherichia coli is catalytically active in the absence of the CydH subunit	30
Mice deficient in the phosphatase activity of sEH show decreased levels of the endocannabinoid 2‐AG in the olfactory bulb and depressive‐like behavior	29
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Fluorescence‐based CRISPR interference system for controlled genetic repression and live single‐cell imaging in mycobacteria	28
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia	28
Front Cover	28
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Front Cover	26
Cas9‐Geminin and Cdt1‐fused anti‐CRISPR protein synergistically increase editing accuracy	26
Presenting the FEBS Letters virtual issue on vesicle biology	26
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Siderophore specificities of the Pseudomonas aeruginosa TonB‐dependent transporters ChtA and ActA	25
Generation of novel anti‐apoE monoclonal antibodies that selectively recognize apoE isoforms	25
Structural and functional insights of itaconyl‐CoA hydratase from Pseudomonas aeruginosa highlight a novel N‐terminal hotdog fold	24
PAT mRNA decapping factors are required for proper development in Arabidopsis	24
Unlocking the biochemical secrets of longevity: balancing healthspan and lifespan	24
A novel approach to single‐cell analysis reveals intrinsic differences in immune marker expression in unstimulated BALB/c and C57BL/6 macrophages	24
MyD88 and not TRIF knockout is sufficient to abolish LPS‐induced inflammatory responses in bone‐derived macrophages	23
Retraction statement: miR‐518b is down‐regulated, and involved in cell proliferation and invasion by targeting Rap1b in esophageal squamous cell carcinoma.	23
‘GutFeel’: an in silico method for predicting gut health status based on the metabolic functional capabilities of the resident microbiome	23
Reactivity of γ‐glutamyl‐cysteine with intracellular and extracellular glutathione metabolic enzymes	23
Interorgan crosstalk mechanisms in disease: the case of acute kidney injury‐induced remote lung injury	23
Homocysteine thiolactone and H2O2 induce amino acid modifications and alter the fibrillation propensity of the Aβ25–35 peptide	23
Class A G protein‐coupled receptors assemble into functional higher‐order hetero‐oligomers	23
HutT functions as the major L‐histidine transporter in Pseudomonas putida KT2440	23
Solving the protein folding problem…	23
Human phytanoyl‐CoA dioxygenase domain‐containing 1 (PHYHD1) is a putative oxygen sensor associated with RNA and carbohydrate metabolism	23
The 19S proteasome subunit Rpt5 reversibly associates with cold‐stable microtubules in glial cells at low temperatures	23
Site‐specific functional roles of the Factor X activation peptide in the intrinsic tenase‐mediated Factor X activation	22
Mechanisms of interorgan crosstalk in health and disease	22
RANBP2 evolution and human disease	21
Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase	21
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Small GTPase signaling hubs at the surface of cellular membranes in physiology and disease	20
Front Cover	20
Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment	20
Front Cover	20
Why science education is more important than most scientists think	20
Membrane occupation and recognition nexus (MORN) motif controls protein localization and function	19
Social context prevents heat hormetic effects against mutagens during fish development	19
Heteromerization between α1B‐adrenoceptor and chemokine (C‐C motif) receptor 2 biases α1B‐adrenoceptor signaling: Implications for vascular funct	19
STAT3 transcriptionally regulates the expression of genes related to glycogen metabolism in developing motor neurons	19
SARS‐CoV‐2‐derived protein Orf9b enhances MARK2 activity via interaction with the autoinhibitory KA1 domain	19
A highly active S1‐P1 nuclease from the opportunistic pathogen Stenotrophomonas maltophilia cleaves c‐di‐GMP	18
Membranes that make fat: roles of membrane lipids as acyl donors for triglyceride synthesis and organelle function	18
A novel perspective on the role of nucleus accumbens neurons in encoding associative learning	18
Gly56 in the synthetic site of isoleucyl‐tRNA synthetase confers specificity and maintains communication with the editing site	18
Structural basis for substrate and antibiotic recognition by Helicobacter pylori isoleucyl‐tRNA synthetase	17
Neuronostatin regulates proliferation and differentiation of rat brown primary preadipocytes	17

Coordinating nucleoporin condensation and nuclear pore complex assembly	17
Characterizing the amino acid activation center of the naturally editing‐deficient aminoacyl‐tRNA synthetase PheRS in Mycoplasma mobile	17
THAP3 recruits SMYD3 to OXPHOS genes and epigenetically promotes mitochondrial respiration in hepatocellular carcinoma	17
Molecular determinants of lipid droplet subpopulations and their fates	17
Disrupting the interaction between a p53 gain‐of‐function mutant and the transcriptional co‐activator PC4 reverses drug resistance in cancer cells	17
It's a two‐way street: Photoswitching and reversible changes of the protein matrix in photoswitchable fluorescent proteins and bacteriophytochromes	16
Does the nuclear envelope retain its identity during mitosis?	16
Front Cover	16
The BcsD subunit of type I bacterial cellulose synthase interacts dynamically with the BcsAB catalytic core complex	16
The S‐adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening	16
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The Melolontha melolontha entomopoxvirus fusolin protein is a chitin‐active lytic polysaccharide monooxygenase that displays extreme stability	16
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Structural differences in the outer membrane‐associated flagellar rings between sheathed and unsheathed flagella	15
An updated classification and mechanistic insights into ligand binding of the substrate‐binding proteins	15
The age‐related decline of helicase function—how G‐quadruplex structures promote genome instability	15
Fanzors, a family of eukaryotic RNA‐guided DNA endonucleases	15
The role of Lin28A and Lin28B in cancer beyond Let‐7	15
Transcription‐coupled DNA repair protects genome stability upon oxidative stress‐derived DNA strand breaks	15
The enigmatic world of tear extracellular vesicles (EVs)–exploring their role in ocular health and beyond	15
The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity	15
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Front Cover	14
Front Cover	14
Retraction Statement: miR‐188 promotes senescence of lineage‐negative bone marrow cells by targeting MAP3K3 expression	14
A scorpion toxin affecting sodium channels shows double cis–trans isomerism	14
Front Cover	14
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Predicting genome‐wide tissue‐specific enhancers via combinatorial transcription factor genomic occupancy analysis	14
AKT controls NLRP3 inflammasome activation by inducing DDX3X phosphorylation	14
Front Cover	14
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Crystal structure of a novel heterooligomeric aminotransferase from Serratia sp. ATCC 39006 provides insights into function	14
Endothelial lipase‐binding peptides similar to netrin‐1 inhibit hepatitis B virus infection	13
Photosystems and photoreceptors in cyanobacterial phototaxis and photophobotaxis	13
GENIGMA: an app to map the 3D genome of cancer cell lines through extreme citizen science	13
Acetylation stabilises calmodulin‐regulated calcium signalling	13
Interferon‐induced protein ISG15 in the central nervous system, quo vadis?	13
GCN2 kinase‐mediated upregulation of ubiquitin C maintains intracellular glutamine level and tRNAGln(CUG) charging under amino acid starvation	13
Bioinspired and biomolecular catalysts for energy conversion and storage	13
MiR‐15b‐5p inhibits castration‐resistant growth of prostate cancer cells by targeting the muscarinic cholinergic receptor CHRM3	13
Deacylases—structure, function, and relationship to diseases	13
Tumour suppressor p53 inhibits hepatitis C virus replication by inducing E6AP‐mediated proteasomal degradation of the viral core protein	13
The 3D‐structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP+ provide glimpses of its catalytic mechanism	13
Engineering ergothioneine production in Yarrowia lipolytica	12
Senile plaques in Alzheimer's disease arise from Aβ‐ and Cathepsin D‐enriched mixtures leaking out during intravascular haemolysis and microaneurysm rupture	12
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Targeting RNA‐binding proteins with small molecules: Perspectives, pitfalls and bifunctional molecules	12
Abiogenesis through gradual evolution of autocatalysis into template‐based replication	12
Lipid droplets and fatty acid‐induced lipotoxicity: in a nutshell	12
ATG and ESCRT control multiple modes of microautophagy	12
Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury	12
Aggregation and mobility of membrane proteins interplay with local lipid order in the plasma membrane of T cells	12
Unorthodox regulation of the MglA Ras‐like GTPase controlling polarity in Myxococcus xanthus	12
From the sideline: Tissue‐specific nucleoporin function in health and disease, an update	12
The roles of molecular chaperones in regulating cell metabolism	12
Middle East respiratory syndrome coronavirus ORF4b protein inhibits TLR7‐ and TLR9‐dependent alpha interferon induction	12
Glutamate dehydrogenase enables Salmonella to survive under oxidative stress and escape from clearance in macrophages	12
Retraction statement: MicroRNA‐520g induces epithelial‐mesenchymal transition and promotes metastasis of hepatocellular carcinoma by targeting SMAD7	11
Odz4 upregulates SAN‐specific genes to promote differentiation into cardiac pacemaker‐like cells	11
Release of FUS into the extracellular space is regulated by its amino‐terminal prion‐like domain	11
The mechanics of the heart: zooming in on hypertrophic cardiomyopathy and cMyBP‐C	11
Krüppel‐like factor 6 participates in extravillous trophoblast cell differentiation and its expression is reduced in abnormally invasive placenta	11
Human WIPI β‐propeller function in autophagy and neurodegeneration	11
Front Cover	11
The survival grip–how cell adhesion promotes tumor maintenance within the microenvironment	11
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum	11
Sticholysin I–II oligomerization in the absence of membranes	11
Integrin β1 transduces the signal for LY6D‐induced macropinocytosis and mediates senescence‐inducing stress‐evoked vacuole formation via FAK	11
Hypoxanthine‐guanine phosphoribosyltransferase is activated via positive cooperativity between guanine and IMP	11
Front Cover	11
Temperature adaptation of yeast phospholipid molecular species at the acyl chain positional level	11
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The clinically relevant triple mutation in the mtND1 gene inactivates Escherichia coli complex I	11
Autophagy as a caretaker of nuclear integrity	11
A nanoemulsified formulation of dolutegravir and epigallocatechin gallate inhibits HIV‐1 replication in cellular models	10
Charged sequence motifs increase the propensity towards liquid–liquid phase separation	10
Lipocalin 2 inhibits actin glutathionylation to promote invasion and migration	10
Structural and functional insights into the enzymatic activities of lipases from Burkholderia stagnalis and Burkholderia plantarii	10
Yeast Sec14‐like lipid transfer proteins Pdr16 and Pdr17 bind and transfer the ergosterol precursor lanosterol in addition to phosphatidylinositol	10

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification	10
Mobile zinc as a modulator of sensory perception	10
The orf virus (ORFV) protein OV20.0 interacts with the microprocessor complex subunit DGCR8 to regulate miRNA biogenesis and ORFV infection	10
STAP‐2 negatively regulates BCR‐mediated B cell activation by recruiting tyrosine‐protein kinase CSK to LYN	10
GABARAP interacts with EGFR — supporting the unique role of this hAtg8 protein during receptor trafficking	10
Amy and Friends: improving the lives of individuals affected by DNA repair disorders	10
Molecular characterization of a moss isoprene synthase provides insight into its evolution	10
Cis‐regulatory evolution underlying the changes in wingless expression pattern associated with wing pigmentation of Drosophila	10
Autophagy in cancer and protein conformational disorders	10
Endocytic proteins mediating GPR15 receptor internalization provide insight into the underlying mechanisms	10
Mitochondrial permeability transition mediated by MTCH2 and F‐ATP synthase contributes to ferroptosis defense	9
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Ablation of fatty acid desaturase 2 (FADS2) exacerbates hepatic triacylglycerol and cholesterol accumulation in polyunsaturated fatty acid‐depleted mice	9
Nuclear pore complex and nucleocytoplasmic transport disruption in neurodegeneration	9
The dual nature of TDC – bridging dendritic and T cells in immunity	9
Autophagy in a Nutshell	9
Front Cover	9
Front Cover	9
Clues to transcription/replication collision‐induced DNA damage: it was RNAP, in the chromosome, with the fork	9
The deubiquitinase USP10 mediates crosstalk between the LKB1/AMPK axis and Wnt/β‐catenin signaling in cancer	9
Front Cover	9
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Nucleocytoplasmic transport at the crossroads of proteostasis, neurodegeneration and neuroprotection	9
Structural determinants for membrane binding of the EGFR juxtamembrane domain	9
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Does Lactobacillus reuteri influence ergothioneine levels in the human body?	8
LIM protein Ajuba promotes liver cell proliferation through its involvement in DNA replication and DNA damage control	8
Blueprints for the scientific society of the future: how FEBS and other scientific societies will have changed 60 years from now	8
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Overactivation of the androgen receptor exacerbates gravid uterine ferroptosis via interaction with and suppression of the NRF2 defense signaling pathway	8
Clinically observed deletions in SARS‐CoV‐2 Nsp1 affect its stability and ability to inhibit translation	8
The winner of the 2024 FEBS Letters Award—an interview with Rachel Flynn	8
Front Cover	8
Activation of the purinergic receptor P2X7 improves hepatosteatosis by promoting lipophagy	8
Hidden biochemical fossils reveal an evolutionary trajectory for glycolysis in the prebiotic era	8
Brain lipidomic profiles of sleep enhancement through co‐administration of alprazolam and CGS21680	8
Quinone chemistry in respiratory complex I involves protonation of a conserved aspartic acid residue	8
Succinate oxidation rescues mitochondrial ATP synthesis at high temperature in Drosophila melanogaster	8
Deletion of the transcription factors Hsf1, Msn2 and Msn4 in yeast uncovers transcriptional reprogramming in response to proteotoxic stress	8
Thiol redox switches regulate the oligomeric state of cyanobacterial Rre1, RpaA and RpaB response regulators	8
Evidence for partial functional overlap of KEA and MSL transport proteins in the chloroplast inner envelope of Arabidopsis thaliana	8
RETRACTION: Theaflavins Retard Human Breast Cancer Cell Migration by Inhibiting NF‐κB via p53‐ROS Cross‐talk	8
Divergent effects of cholesterol on the structure and fluidity of liposome and catanionic vesicle membranes	8
Corrigendum	8
The FEBS 60th anniversary writing contest—blueprints for the scientific society of tomorrow	8
Front Cover	8
The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation	8
A new approach to making scientific research more efficient – rethinking sustainability	8
F‐actin determines the time‐dependent shift in docking dynamics of glucagon‐like peptide‐1 granules upon stimulation of secretion	8
The prolyl hydroxylase OGFOD1 promotes cancer cell proliferation by regulating the expression of cell cycle regulators	8
Front Cover	8
HNF4α overexpression enhances the therapeutic potential of umbilical cord mesenchymal stem/stromal cells in mice with acute liver failure	7
Structure and stability of phycocyanin from thermotolerant Oscillatoria	7
Spontaneous and chaperone‐assisted metal loading in the active site of protein phosphatase‐1	7
Transcription as a double‐edged sword in genome maintenance	7
Front Cover	7
Two phosphoenolpyruvate carboxykinases with differing biochemical properties in Chlamydomonas reinhardtii	7
Two years into COVID‐19 – Lessons in SARS‐CoV‐2 and a perspective from papers in FEBS Letters	7
Dissecting the Ca2+ dependence of DesA1 function in Mycobacterium tuberculosis	7
ABC transporter activity is affected by the size of lipid nanodiscs	7
The structure of a Lactobacillus helveticus chlorogenic acid esterase and the dynamics of its insertion domain provide insights into substrate binding	7
The chromatin repressors EZH2 and Suv4‐20h coregulate cell fate specification during hippocampal development	7
hnRNPA1 enhances FOXP3 stability to promote the differentiation and functions of regulatory T cells	7
Distinct classes of misfolded proteins differentially affect the growth of yeast compromised for proteasome function	7
Roles of methionine and cysteine residues of the Escherichia coli sensor kinase HprS in reactive chlorine species sensing	7
Age‐associated myeloid malignancies – the role of STAT3 and STAT5 in myelodysplastic syndrome and acute myeloid leukemia	7
Reducing plastic waste in scientific protocols by 65% — practical steps for sustainable research	7
Characterization of molecular mechanisms of CaMKKα/1 oligomerization	7
Neurospora casein kinase 1a recruits the circadian clock protein FRQvia the C‐terminal lobe of its kinase domain	7
Liver gene transfer for metabolite detoxification in inherited metabolic diseases	7
Exogenous fatty acids inhibit fatty acid synthesis by competing with endogenously generated substrates for phospholipid synthesis in Escherichia coli	7
Binding mechanism of adenylate kinase‐specific monobodies	7
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Strigolactone biosynthesis in rice can occur via a 9‐cis‐3‐OH‐10′‐apo‐β‐carotenal intermediate	7
RETRACTION: Role of the PDK1–PKB–GSK3 Pathway in Regulating Glycogen Synthase and Glucose Uptake in the Heart	7
Arabidopsis mutants lacking DLDG1 and non‐photochemical quenching‐related proteins reveal the regulatory role of DLDG1 in chloroplast pH homeostasis	7
A single evolutionarily divergent mutation determines the different FAD‐binding affinities of human and rat NQO1 due to site‐specific phosphorylation	7
Conjugative transfer of the IncN plasmid pKM101 is mediated by dynamic interactions between the TraK accessory factor and TraI	7
Small RNA sequencing in hypoxic naked mole‐rat hearts suggests microRNA regulation of RNA‐ and translation‐related processes	7
'The world needs science, and science needs women'…but what do women in science need? – interviews and panel discussion with 5 outstanding female scientists	7
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A guide for blood–brain barrier models	7
Comparative characterization of nine novel GH51, GH54 and GH62 α‐l‐arabinofuranosidases from Penicillium subrubescens	7
Corrigendum: His‐163 is a stereospecific proton donor in the mechanism of d‐glucosaminate‐6‐phosphate ammonia‐lyase	7
The scorpion toxin BeKm‐1 blocks hERG cardiac potassium channels using an indispensable arginine residue	7
Front Cover	7
The radical impact of oxygen on prokaryotic evolution—enzyme inhibition first, uninhibited essential biosyntheses second, aerobic respiration third	7
You are who your friends are—nuclear pore proteins as components of chromatin‐binding complexes	7
Knockout of the BRAP homolog in mice leads to abnormal tracheal cilia	7
EZH2 modulates retinoic acid signaling to ensure myotube formation during development	7
Single‐dose immunisation with a multimerised SARS‐CoV‐2 receptor binding domain (RBD) induces an enhanced and protective response in mice	7
Transforming science communication through storytelling	7
A Pellino‐2 variant is associated with constitutive NLRP3 inflammasome activation in a family with ocular pterygium–digital keloid dysplasia	7