FEBS Letters

Papers
(The TQCC of FEBS Letters is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
Front Cover152
Front Cover106
A two‐step mechanism for the binding of the HIV‐1 MPER epitope by the 10E8 antibody onto biosensor‐supported lipid bilayers58
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Mapping secondary substrate‐binding sites on the GH11 xylanase from Bacillus subtilis53
Clinical and mechanistic insights into the roles of DDX41 in haematological malignancies53
Artificial miRNAs derived from miR‐181 family members have potential in cancer therapy due to an altered spectrum of target mRNAs44
CRK and NCK adaptors may functionally overlap in zebrafish neurodevelopment, as indicated by common binding partners and overlapping expression patterns44
miR‐4734 conditionally suppresses ER stress‐associated proinflammatory responses43
Interdomain electron transfer in flavohaemoglobin from Candida norvegensis with antibiotic azole compounds41
The ubiquitin–proteasome system and autophagy mutually interact in neurotoxin‐induced dopaminergic cell death models of Parkinson's disease41
The fatty acid synthase inhibitor C75 differentially affects the adipogenic differentiation of multipotent cells and preadipocytes41
Valosin‐containing protein regulates the stability of fused in sarcoma granules in cells by changing ATP concentrations39
Mycobacterium tuberculosis low molecular weight T‐cell antigen Mtb8.4 has heme‐binding and fiber‐forming properties39
Silica‐coated magnetic nanobeads in a flow enrichment target capture Halbach ( FETCH ) magnetic separation system for circulating tumor cell enrichme38
Spatial regulation of ARL3 and GSF‐mediated lipidated cargo trafficking in the primary cilium38
Insight into the function of the Golgi membrane protein GOLM1 in cholangiocytes through interactomic analysis38
Mice deficient in the phosphatase activity of sEH show decreased levels of the endocannabinoid 2‐ AG 37
Purification tags markedly affect self‐aggregation of CPEB336
ArabidopsisRAN GTPases are critical for mitosis during male and female gametogenesis35
Mechanisms and kinetic assays of aminoacyl‐ tRNA synthetases34
The bacterial MRE11RAD50 and DNA234
The inhibitory SAPS3AMPK interaction detected in HEK293 34
Reciprocal control of viral infection and phosphoinositide dynamics34
Cytochrome bd‐I from Escherichia coli is catalytically active in the absence of the CydH subunit32
Heparin promotes rapid fibrillation of the basic parathyroid hormone at physiological pH32
Microscopic modulation and analysis of islets of Langerhans in living zebrafish larvae32
Promiscuous activity of β‐carotene hydroxylase CrtZ on epoxycarotenoids leads to the formation of rare carotenoids with 6‐hydroxy‐3‐keto‐ε‐ends31
Cordycepin generally inhibits growth factor signal transduction in a systems pharmacology study31
Skraban‐Deardorff intellectual disability syndrome‐associated mutations in WDR 26 impair CTLH E 3 31
Molecular and mechanical mechanisms of animal cell abscission31
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Front Cover30
Novel insights into autophagosome biogenesis revealed by cryo‐electron tomography30
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A working model for cytoplasmic assembly of H/ACA snoRNPs29
The 19S proteasome subunit Rpt5 reversibly associates with cold‐stable microtubules in glial cells at low temperatures29
Structural and functional insights of itaconyl‐CoA hydratase from Pseudomonas aeruginosa highlight a novel N‐terminal hotdog fold29
Autophagy in the regulation of cancer dormancy28
Site‐specific functional roles of the Factor X activation peptide in the intrinsic tenase‐mediated Factor X activation28
Unlocking the biochemical secrets of longevity: balancing healthspan and lifespan28
Cell culture pioneer Jaroslav Cinatl—the pursuit and defence of truth27
Intron‐oriented HTLV ‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 27
Interorgan crosstalk mechanisms in disease: the case of acute kidney injury‐induced remote lung injury27
MyD88 and not TRIF knockout is sufficient to abolish LPS‐induced inflammatory responses in bone‐derived macrophages26
Human phytanoyl‐CoA dioxygenase domain‐containing 1 (PHYHD1) is a putative oxygen sensor associated with RNA and carbohydrate metabolism26
Generation of novel anti‐apo E monoclonal antibodies that selectively recognize apo E isoforms26
Siderophore specificities of the Pseudomonas aeruginosa TonB‐dependent transporters ChtA and ActA25
Reactivity of γ‐glutamyl‐cysteine with intracellular and extracellular glutathione metabolic enzymes25
Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy25
A novel approach to single‐cell analysis reveals intrinsic differences in immune marker expression in unstimulated BALB/c and C57BL/6 macrophages24
Cas9‐Geminin and Cdt1‐fused anti‐CRISPR protein synergistically increase editing accuracy24
PAT m RNA decapping factors are required for proper development in Arabidopsis23
RANBP2 evolution and human disease23
Homocysteine thiolactone and H2O2 induce amino acid modifications and alter the fibrillation propensity of the Aβ25–35 peptide23
Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase23
Insights into PI3K / AKT signaling in B cell development and chronic lymphocytic leukemia23
Retraction statement: miR ‐518b is down‐regulated, and involved in cell proliferation and invasion by targeting Rap1b in esophageal squamous cell car22
Mechanisms of interorgan crosstalk in health and disease22
Fluorescence‐based CRISPR interference system for controlled genetic repression and live single‐cell imaging in mycobacteria22
Solving the protein folding problem…21
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Characterizing the amino acid activation center of the naturally editing‐deficient aminoacyl‐tRNA synthetase PheRS in Mycoplasma mobile20
Small GTPase signaling hubs at the surface of cellular membranes in physiology and disease20
Why science education is more important than most scientists think20
Neuronostatin regulates proliferation and differentiation of rat brown primary preadipocytes20
Front Cover20
Does the nuclear envelope retain its identity during mitosis?20
Front Cover20
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Fanzors, a family of eukaryotic RNA‐guided DNA endonucleases19
It's a two‐way street: Photoswitching and reversible changes of the protein matrix in photoswitchable fluorescent proteins and bacteriophytochromes19
Heteromerization between α1B‐adrenoceptor and chemokine (C‐C motif) receptor 2 biases α1B‐adrenoceptor signaling: Implications for vascular funct19
The S‐adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening19
STAT3 transcriptionally regulates the expression of genes related to glycogen metabolism in developing motor neurons18
Structural basis for substrate and antibiotic recognition by Helicobacter pylori isoleucyl‐t RNA synth18
Coordinating nucleoporin condensation and nuclear pore complex assembly18
The enigmatic world of tear extracellular vesicles (EVs)–exploring their role in ocular health and beyond18
The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity18
The cytochrome oxidase defect in ISC ‐depleted yeast is caused by impaired iron–sulfur cluster maturation of the mitoribosome assembly factor Rsm2217
Gly56 in the synthetic site of isoleucyl‐tRNA synthetase confers specificity and maintains communication with the editing site17
THAP 3 recruits SMYD 3 to OXPHOS genes and epigenetically promotes 17
Structural differences in the outer membrane‐associated flagellar rings between sheathed and unsheathed flagella17
A scorpion toxin affecting sodium channels shows double cistrans isomerism17
Social context prevents heat hormetic effects against mutagens during fish development17
Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment17
SARSC o V ‐2‐derived protein Orf9b enhances 17
The role of Lin28A and Lin28B in cancer beyond Let‐716
The BcsD subunit of type I bacterial cellulose synthase interacts dynamically with the BcsAB catalytic core complex16
Membranes that make fat: roles of membrane lipids as acyl donors for triglyceride synthesis and organelle function16
A novel perspective on the role of nucleus accumbens neurons in encoding associative learning16
Disrupting the interaction between a p53 gain‐of‐function mutant and the transcriptional co‐activator PC4 reverses drug resistance in cancer cells16
Molecular determinants of lipid droplet subpopulations and their fates16
A highly active S1‐P1 nuclease from the opportunistic pathogen Stenotrophomonas maltophilia cleaves c‐di‐GMP16
Kit structural mutations associated with the porcine dominant white phenotype impair hematopoiesis in mice16
Membrane occupation and recognition nexus (MORN) motif controls protein localization and function16
The Melolontha melolontha entomopoxvirus fusolin protein is a chitin‐active lytic polysaccharide monooxygenase that displays extreme stability16
Transcription‐coupled DNA repair protects genome stability upon oxidative stress‐derived DNA stran15
Front Cover15
The age‐related decline of helicase function—how G‐quadruplex structures promote genome instability15
Front Cover15
The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases15
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Front Cover14
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Acetylation stabilises calmodulin‐regulated calcium signalling14
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells14
Glutamate dehydrogenase enables Salmonella to survive under oxidative stress and escape from clearance in macrophages14
Retraction Statement: miR‐188 promotes senescence of lineage‐negative bone marrow cells by targeting MAP3K3 expression14
Endothelial lipase‐binding peptides similar to netrin‐1 inhibit hepatitis B virus infection14
Middle East respiratory syndrome coronavirus ORF4b protein inhibits TLR7‐ and TLR9‐dependent alpha interferon induction14
Bioinspired and biomolecular catalysts for energy conversion and storage14
GCN2 kinase‐mediated upregulation of ubiquitin C maintains intracellular glutamine level and tRNAGln(CUG) charging under amino acid starvation14
Front Cover14
GENIGMA: an app to map the 3D genome of cancer cell lines through extreme citizen science14
Front Cover14
Abiogenesis through gradual evolution of autocatalysis into template‐based replication14
A coiled‐coil domain triggers oligomerization of MmpL10 , the mycobacterial transporter of trehalose polyphleate precursor13
The 3D‐structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP+ provide glimpses of its catalytic mechanism13
Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury13
Unorthodox regulation of the MglA Ras‐like GTPase controlling polarity in Myxococcus xanthus13
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl113
Photosystems and photoreceptors in cyanobacterial phototaxis and photophobotaxis13
Tumour suppressor p53 inhibits hepatitis C virus replication by inducing E6AP‐mediated proteasomal degradation of the viral core protein13
Predicting genome‐wide tissue‐specific enhancers via combinatorial transcription factor genomic occupancy analysis13
Deacylases—structure, function, and relationship to diseases13
Senile plaques in Alzheimer's disease arise from Aβ‐ and Cathepsin D‐enriched mixtures leaking out during intravascular haemolysis and microaneurysm rupture13
MiR‐15b‐5p inhibits castration‐resistant growth of prostate cancer cells by targeting the muscarinic cholinergic receptor CHRM312
Lipid droplets and fatty acid‐induced lipotoxicity: in a nutshell12
ATG and ESCRT control multiple modes of microautophagy12
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 112
From the sideline: Tissue‐specific nucleoporin function in health and disease, an update12
The roles of molecular chaperones in regulating cell metabolism12
Retraction statement: MicroRNA‐520g induces epithelial‐mesenchymal transition and promotes metastasis of hepatocellular carcinoma by targeting SMAD712
Interferon‐induced protein ISG15 in the central nervous system, quo vadis?12
Targeting RNA‐binding proteins with small molecules: Perspectives, pitfalls and bifunctional molecules12
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Crystal structure of a novel heterooligomeric aminotransferase from Serratia sp. ATCC 39006 provides i12
Engineering ergothioneine production in Yarrowia lipolytica12
Molecular characterization of a moss isoprene synthase provides insight into its evolution11
Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification11
The mechanics of the heart: zooming in on hypertrophic cardiomyopathy and cMyBP‐C11
GABARAP interacts with EGFR — supporting the unique role of this hAtg8 protein during receptor trafficking11
Amy and Friends: improving the lives of individuals affected by DNA repair disorders11
Autophagy in cancer and protein conformational disorders11
Autophagy as a caretaker of nuclear integrity11
Endocytic proteins mediating GPR15 receptor internalization provide insight into the underlying mechanisms11
Cis ‐regulatory evolution underlying the changes in wingless expression pattern associated with wing pigmentation of 11
The clinically relevant triple mutation in the mtND1 gene inactivates Escherichia coli complex I11
A nanoemulsified formulation of dolutegravir and epigallocatechin gallate inhibits HIV‐1 replication in cellular models11
Hypoxanthine‐guanine phosphoribosyltransferase is activated via positive cooperativity between guanine and IMP11
Mobile zinc as a modulator of sensory perception11
Temperature adaptation of yeast phospholipid molecular species at the acyl chain positional level11
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STAP ‐2 negatively regulates BCR ‐mediated B cell activation by recruiting tyrosine‐protein kinase 11
Structural and functional insights into the enzymatic activities of lipases from Burkholderia stagnalis and Burkholderia plantarii11
Sticholysin I–II oligomerization in the absence of membranes11
Krüppel‐like factor 6 participates in extravillous trophoblast cell differentiation and its expression is reduced in abnormally invasive placenta11
Release of FUS into the extracellular space is regulated by its amino‐terminal prion‐like domain11
Charged sequence motifs increase the propensity towards liquid–liquid phase separation10
The winner of the 2024 FEBS Letters Award—an interview with Rachel Flynn10
Integrin β1 transduces the signal for LY6D‐induced macropinocytosis and mediates senescence‐inducing stress‐evoked vacuole formation via FAK10
Front Cover10
Odz4 upregulates SAN ‐specific genes to promote differentiation into cardiac pacemaker‐like cells10
Yeast Sec14‐like lipid transfer proteins Pdr16 and Pdr17 bind and transfer the ergosterol precursor lanosterol in addition to phosphatidylinositol10
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The dual nature of TDC – bridging dendritic and T cells in immunity10
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A new approach to making scientific research more efficient – rethinking sustainability10
The survival grip–how cell adhesion promotes tumor maintenance within the microenvironment10
Thiol redox switches regulate the oligomeric state of cyanobacterial Rre1, RpaA and RpaB response regulators10
Autophagy in a Nutshell10
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Lipocalin 2 inhibits actin glutathionylation to promote invasion and migration10
Front Cover10
Nucleocytoplasmic transport at the crossroads of proteostasis, neurodegeneration and neuroprotection10
Advances in the development of organoid‐based models of the trachea and esophagus10
EXPRESSION OF CONCERN: Introgression of a Novel Salt‐Tolerant L‐Myo‐Inositol 1‐Phosphate Synthase from Porteresia Coarctata (Roxb.) Tateoka (PcINO1) Confers Salt Tolera10
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum10
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Human WIPI β‐propeller function in autophagy and neurodegeneration10
Front Cover10
F‐actin determines the time‐dependent shift in docking dynamics of glucagon‐like peptide‐1 granules upon stimulation of secretion10
Front Cover9
Diacylglycerol kinase ε depletion suppresses LPS ‐stimulated NFκB9
Nuclear pore complex and nucleocytoplasmic transport disruption in neurodegeneration9
Deletion of the transcription factors Hsf1, Msn2 and Msn4 in yeast uncovers transcriptional reprogramming in response to proteotoxic stress9
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Front Cover9
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Evidence for partial functional overlap of KEA and MSL transport proteins in the chloroplast inner9
The prolyl hydroxylase OGFOD1 promotes cancer cell proliferation by regulating the expression of cell cycle regulators9
Structural determinants for membrane binding of the EGFR juxtamembrane domain9
Succinate oxidation rescues mitochondrial ATP synthesis at high temperature in Drosophila melanogaster9
Characterization of molecular mechanisms of CaMKKα/1 oligomerization9
Front Cover9
RETRACTION: Theaflavins Retard Human Breast Cancer Cell Migration by Inhibiting NF‐κB via p53‐ROS Cross‐talk9
The FEBS 60th anniversary writing contest—blueprints for the scientific society of tomorrow9
Mitochondrial permeability transition mediated by MTCH2 and F‐ ATP synthase contributes to ferropt9
The deubiquitinase USP10 mediates crosstalk between the LKB1/AMPK axis and Wnt/β‐catenin signaling in cancer9
Clinically observed deletions in SARS‐CoV‐2 Nsp1 affect its stability and ability to inhibit translation9
Clues to transcription/replication collision‐induced DNA damage: it was RNAP , in the chromosome, 9
Overactivation of the androgen receptor exacerbates gravid uterine ferroptosis via interaction with and suppression of the NRF2 defense signaling pathway9
LIM protein Ajuba promotes liver cell proliferation through its involvement in DNA replication and DNA damage control9
Blueprints for the scientific society of the future: how FEBS and other scientific societies will have changed 60 years from now9
Front Cover9
You are who your friends are—nuclear pore proteins as components of chromatin‐binding complexes8
Brain lipidomic profiles of sleep enhancement through co‐administration of alprazolam and CGS216808
Conjugative transfer of the I nc N plasmid p KM 8
HNF4α overexpression enhances the therapeutic potential of umbilical cord mesenchymal stem/stromal cells in mice with acute liver failure8
Liver gene transfer for metabolite detoxification in inherited metabolic diseases8
Strigolactone biosynthesis in rice can occur via a 9‐cis‐3‐OH‐10′‐apo‐β‐carotenal intermediate8
A single evolutionarily divergent mutation determines the different FAD‐binding affinities of human and rat NQO1 due to site‐specific phosphorylation8
Dissecting the Ca 2+ dependence of DesA1 function in Mycobacterium tuberculosis8
Arabidopsis mutants lacking DLDG1 and non‐photochemical quenching‐related proteins reveal the regulatory role of DLDG1 in chloroplast pH homeostasis8
The scorpion toxin BeKm‐1 blocks hERG cardiac potassium channels using an indispensable arginine residue8
Transcription as a double‐edged sword in genome maintenance8
C9orf72 ALS ‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules8
Does Lactobacillus reuteri influence ergothioneine levels in the human body?8
A γ‐glutamyl hydrolase lacking the signal peptide confers susceptibility to folates/antifolates in acute lymphoblastic leukemia cells8
Two phosphoenolpyruvate carboxykinases with differing biochemical properties in Chlamydomonas reinhardtii8
Phosphoinositides in membrane remodeling during infections and cellular stresses8
The structure of a Lactobacillus helveticus chlorogenic acid esterase and the dynamics of its insertion domain provide insights into substrate binding8
Five problems plaguing publishing in the life sciences—and one common cause8
Urinary microRNA profiling in pregnant women identifies placental microRNAs that are candidate biomarkers for monitoring placental health8
Knockout of the BRAP homolog in mice leads to abnormal tracheal cilia8
Decline of ergothioneine in frailty and cognition impairment8
Binding mechanism of adenylate kinase‐specific monobodies8
The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation8
Comparative characterization of nine novel GH51, GH54 and GH62 α‐l‐arabinofuranosidases from Penicillium subrubescens8
Hidden biochemical fossils reveal an evolutionary trajectory for glycolysis in the prebiotic era8
The chromatin repressors EZH2 and Suv4‐20h coregulate cell fate specification during hippocampal development8
EZH2 modulates retinoic acid signaling to ensure myotube formation during development8
Divergent effects of cholesterol on the structure and fluidity of liposome and catanionic vesicle membranes8
The radical impact of oxygen on prokaryotic evolution—enzyme inhibition first, uninhibited essential biosyntheses second, aerobic respiration third8
ABC transporter activity is affected by the size of lipid nanodiscs8
Human PHOSPHO1 exhibits phosphatidylcholine‐ and phosphatidylethanolamine‐phospholipase C activities and interacts with diacylglycerol kinase δ7
The role and implications of mammalian cellular circadian entrainment7
Circulating histones as clinical biomarkers in critically ill conditions7
Adding hydrophobicity or positive charges to the cytosolic half of the α‐synuclein 3–11 helix increases membrane association and S129 phosphorylation7
Structure and stability of phycocyanin from thermotolerant Oscillatoria7
Poliovirus capsid protein VP3 can penetrate vascular endothelial cells7
The activator/repressor Hap1 binds to the yeast eIF5A‐encoding gene TIF51A to adapt its expression to the mitochondrial functional status7
Exogenous fatty acids inhibit fatty acid synthesis by competing with endogenously generated substrates for phospholipid synthesis in Escherichia coli7
Structural basis of a GatC ortholog transporter in the bacterial phosphotransferase system7
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