FEBS Letters

Article	Citations
The prefoldin‐like protein AtURI exhibits characteristics of intrinsically disordered proteins	192
Art and Science break boundaries in The Garden of Earthly Delights	155
Front Cover	103
Time‐resolved transcriptomics of mouse gastric pit cells during postnatal development reveals features distinct from whole stomach development	76
Probing the legitimate initiation of RNA synthesis by Qβ replicase with oligonucleotide primers	74
Front Cover	59
Sharing biological data: why, when, and how	58
The autophagy of stress granules	45
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Glu592 of the axon guidance receptor ROBO3 mediates a pH‐dependent interaction with NELL2 ligand	42
RETRACTION: Theaflavins Retard Human Breast Cancer Cell Migration by Inhibiting NF‐κB via p53‐ROS Cross‐talk	40
Suppression of amber stop codons impairs pathogenicity in Salmonella	39
Knockout of the BRAP homolog in mice leads to abnormal tracheal cilia	38
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Front Cover	37
Transcription as a double‐edged sword in genome maintenance	37
Front Cover	33
Are casein micelles extracellular condensates formed by liquid‐liquid phase separation?	33
Binding and/or hydrolysis of purine‐based nucleotides is not required for IM30 ring formation	32
The radical impact of oxygen on prokaryotic evolution—enzyme inhibition first, uninhibited essential biosyntheses second, aerobic respiration third	31
Structure‐based design of peptidomimetic inhibitors of PSD‐95 with improved affinity for the PDZ3 domain	31
EGR1 plays an important role in BMP9‐mediated osteoblast differentiation by promoting SMAD1/5 phosphorylation	31
A γ‐glutamyl hydrolase lacking the signal peptide confers susceptibility to folates/antifolates in acute lymphoblastic leukemia cells	30
Front Cover	30
Front Cover	30

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Divergent effects of cholesterol on the structure and fluidity of liposome and catanionic vesicle membranes	28
Mutational analysis of the functional motifs of the DEAD‐box RNA helicase Me31B/DDX6 in Drosophila germline development	27
NADPH‐to‐NADH conversion by mitochondrial transhydrogenase is indispensable for sustaining anaerobic metabolism in Euglena gracilis	27
Artificial miRNAs derived from miR‐181 family members have potential in cancer therapy due to an altered spectrum of target mRNAs	26
Changes in importin levels promote nuclear proteasomal degradation of cell cycle‐related proteins during THP‐1 monocyte‐to‐macrophage differentiation	26
Inclusion, belonging, and institutional climate – overlooked factors driving diverse STEM faculty turnover?	26
ABC transporter activity is affected by the size of lipid nanodiscs	26
Front Cover	26
Front Cover	25
Front Cover	25
Mycobacterium tuberculosis low molecular weight T‐cell antigen Mtb8.4 has heme‐binding and fiber‐forming properties	24
The fatty acid synthase inhibitor C75 differentially affects the adipogenic differentiation of multipotent cells and preadipocytes	24
Overexpression of polyphosphate polymerases and deletion of polyphosphate phosphatases shorten the replicative lifespan in yeast	23
Front Cover	23
Retraction Statement: The circadian rhythm regulator RpaA modulates photosynthetic electron transport and alters the preferable temperature range for growth in a cyanobacterium	22
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases	22
Retraction statement: MicroRNA‐575 targets BLID to promote growth and invasion of non‐small cell lung cancer cells	22
Insight into the function of the Golgi membrane protein GOLM1 in cholangiocytes through interactomic analysis	22
Expression of Concern	22
Secreted acid phosphatases maintain replicative lifespan via inositol polyphosphate metabolism in budding yeast	21
Phenylalanine stacking enhances the red fluorescence of biliverdin IXα on UV excitation in sandercyanin fluorescent protein	21
Front Cover	21
Reprogramming nucleolar size by genetic perturbation of the extranuclear Rab GTPases Ypt6 and Ypt32	21
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CRK and NCK adaptors may functionally overlap in zebrafish neurodevelopment, as indicated by common binding partners and overlapping expression patterns	21
Front Cover	21
Interdomain electron transfer in flavohaemoglobin from Candida norvegensis with antibiotic azole compounds	20
iChIP‐SILAC analysis identifies epigenetic regulators of CpG methylation of the p16INK4A gene	20
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Front Cover	20
Comparative structural and functional analysis of the glycine‐rich regions of Class A and B J‐domain protein cochaperones of Hsp70	19
BRET analysis reveals interaction between the lysophosphatidic acid receptor LPA2 and the lysophosphatidylinositol receptor GPR55 in live cells	19
Distinct classes of misfolded proteins differentially affect the growth of yeast compromised for proteasome function	19
dAsap regulates cellular protrusions via an Arf6‐dependent actin regulatory pathway in S2R+ cells	19
The structure of a Lactobacillus helveticus chlorogenic acid esterase and the dynamics of its insertion domain provide insights into substrate binding	19
Heparin promotes rapid fibrillation of the basic parathyroid hormone at physiological pH	18
When faculty are bullied: the unacceptable costs of doing our job and what universities can and should do	18
Front Cover	18
Longin domain GAP complexes in nutrient signalling, membrane traffic and neurodegeneration	18
Dietary (poly)phenols as modulators of the biophysical properties in endothelial cell membranes: its impact on nitric oxide bioavailability in hypertension	18
The Ca2+‐binding protein sorcin stimulates transcriptional activity of the unfolded protein response mediator ATF6	18
Comparative characterization of nine novel GH51, GH54 and GH62 α‐l‐arabinofuranosidases from Penicillium subrubescens	18
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Plant autophagy and intracellular trafficking	17
Front Cover	17
Loss of tRNA methyltransferase 9 and DNA damage response genes in yeast confers sensitivity to aminoglycosides	17
Microscopic modulation and analysis of islets of Langerhans in living zebrafish larvae	16
Strigolactone biosynthesis in rice can occur via a 9‐cis‐3‐OH‐10′‐apo‐β‐carotenal intermediate	16
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Crystal structure and enzyme engineering of the broad substrate spectrum l‐amino acid oxidase 4 from the fungus Hebeloma cylindrosporum	16
The dopamine receptor agonist apomorphine stabilizes neurotoxic α‐synuclein oligomers	16
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Urinary microRNA profiling in pregnant women identifies placental microRNAs that are candidate biomarkers for monitoring placental health	16
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Molecular handcraft of a well‐folded protein chimera	16
Hidden biochemical fossils reveal an evolutionary trajectory for glycolysis in the prebiotic era	15
Cryo‐electron microscopy of Na+,K+‐ATPase reveals how the extracellular gate locks in the E2·2K+ state	15
Integration of DNA–RNA‐triplex‐based regulation of transcription into molecular logic gates	15
Cytochrome bd‐I from Escherichia coli is catalytically active in the absence of the CydH subunit	15
N‐acetyloxfenicine strongly induces mitohormesis in mice as well as in insects	15
Does Lactobacillus reuteri influence ergothioneine levels in the human body?	15
Front Cover	15
A cell surface‐reducing microenvironment induces early osteogenic commitment	15
HNF4α overexpression enhances the therapeutic potential of umbilical cord mesenchymal stem/stromal cells in mice with acute liver failure	15
CCDC115 inhibits autophagy‐mediated degradation of YAP to promote cell proliferation	14
Interleukin‐6–interleukin‐11 receptor chimeras reveal ionomycin‐induced proteolysis beyond ADAM10	14
Skraban‐Deardorff intellectual disability syndrome‐associated mutations in WDR26 impair CTLH E3 complex assembly	14
HIV‐1 replication requires optimal activation of the unfolded protein response	14
Shedding Light on the Role of Phosphorylation in Plant Autophagy	14
Apolipoprotein E isoforms and their Cys‐thiol modifications impact LRP1‐mediated metabolism of triglyceride‐rich lipoproteins	14
Asp56 in actin is critical for the full activity of the amino acid starvation‐responsive kinase Gcn2	14
A simplified and easy‐to‐use HIP HOP assay provides insights into chalcone antifungal mechanisms of action	14
LIM protein Ajuba promotes liver cell proliferation through its involvement in DNA replication and DNA damage control	13
Decline of ergothioneine in frailty and cognition impairment	13
The Beautiful Brain: communicating fundamental neuroscience through masterpieces of art	13
Fragment‐based discovery of small molecule inhibitors of the HDGFRP2 PWWP domain	13
Location of the photosynthetic carbon metabolism in microcompartments and separated phases in microalgal cells	13
T‐cell immunosuppression in sepsis is augmented by sciatic denervation‐induced skeletal muscle atrophy	13
Diacylglycerol kinase alleviates autophagic degradation of the endoplasmic reticulum in SPT10‐deficient yeast to enhance triterpene biosynthesis	12
Single protonation of the reduced quinone in respiratory complex I drives four‐proton pumping	12
Mapping secondary substrate‐binding sites on the GH11 xylanase from Bacillus subtilis	12
Valosin‐containing protein regulates the stability of fused in sarcoma granules in cells by changing ATP concentrations	12
The APC10 subunit of the anaphase‐promoting complex/cyclosome orchestrates NLRP3 inflammasome activation during the cell cycle	12
PACS‐1 contains distinct motifs for nuclear‐cytoplasmic transport and interacts with the RNA‐binding protein PTBP1 in the nucleus and cytosol	12
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The chromatin repressors EZH2 and Suv4‐20h coregulate cell fate specification during hippocampal development	12
miR‐4734 conditionally suppresses ER stress‐associated proinflammatory responses	12
Localization of the ubiquitin ligase Dma1 to the fission yeast contractile ring is modulated by phosphorylation	12
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Front Cover	11
Puzzling out nuclear pore complex assembly	11
Structural characterization of the porcine adeno‐associated virus Po1 capsid protein binding to the nuclear trafficking protein importin alpha	11
Multiorgan microphysiological systems as tools to interrogate interorgan crosstalk and complex diseases	11
Activity of the pleiotropic drug resistance transcription factors Pdr1p and Pdr3p is modulated by binding site flanking sequences	11
Crossing paths: recent insights in the interplay between autophagy and intracellular trafficking in plants	11
You are who your friends are—nuclear pore proteins as components of chromatin‐binding complexes	11
ArabidopsisRAN GTPases are critical for mitosis during male and female gametogenesis	11
Transforming properties of MET receptor exon 14 skipping can be recapitulated by loss of the CBL ubiquitin ligase binding site	11
Transcriptomic insights into the virulence of Acinetobacter baumannii during infection—role of iron uptake and siderophore production genes	11
Sphingomyelinases in a journey to combat arthropod‐borne pathogen transmission	11
Dynamical activation of function in metalloenzymes	11
Increased ROS levels in mitochondrial outer membrane protein Mul1‐deficient oocytes result in abnormal preimplantation embryogenesis	10
Brain lipidomic profiles of sleep enhancement through co‐administration of alprazolam and CGS21680	10
Molecular and mechanical mechanisms of animal cell abscission	10
Basic fibroblast growth factor uniquely stimulates quiescent vascular smooth muscle cells and induces proliferation and dedifferentiation	10
Quinone chemistry in respiratory complex I involves protonation of a conserved aspartic acid residue	10
Front Cover	10
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Identification of novel anti‐leishmanials targeting glutathione synthetase of the parasite: a drug repurposing approach	10
Micromanaging the neuroendocrine system – A review on miR‐7 and the other physiologically relevant miRNAs in the hypothalamic–pituitary axis	10
Epitope analysis of human monoclonal antibodies from a patient with autoimmune factor XIII deficiency reveals their inhibitory mechanisms	10
α‐Helices propagating from stable nucleators exhibit unconventional thermal folding	10
Mitochondrial respiratory complex I can be inhibited via bypassing the ubiquinone‐accessing tunnel	10
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Peroxisomes undergo morphological changes in a light‐dependent manner with proximity to the nucleus	10
IL‐6 mediated CD206+ARG‐1+ tumor associated macrophage polarization induces Treg infiltration in non‐responder luminal A breast cancer	10
Activation of the purinergic receptor P2X7 improves hepatosteatosis by promoting lipophagy	10
Nrf2 as a regulator of energy metabolism and mitochondrial function	10
Cordycepin generally inhibits growth factor signal transduction in a systems pharmacology study	10
Gene editing in liver diseases	10
Arabidopsis mutants lacking DLDG1 and non‐photochemical quenching‐related proteins reveal the regulatory role of DLDG1 in chloroplast pH homeostasis	10
Remodelling of mitochondrial function by import of specific lipids at multiple membrane‐contact sites	10
Thermodynamic versus kinetic basis for the high conformational stability of nanobodies for therapeutic applications	10
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SARS‐CoV‐2 spike protein aggregation is triggered by bacterial lipopolysaccharide	9
The proximity interactome of PML isoforms I and II under fatty acid stress	9
Crystal structure of the stalk region of axonemal inner‐arm dynein‐d reveals unique features in the coiled‐coil and microtubule‐binding domain	9
The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation	9
The scorpion toxin BeKm‐1 blocks hERG cardiac potassium channels using an indispensable arginine residue	9

Mice deficient in the phosphatase activity of sEH show decreased levels of the endocannabinoid 2‐AG in the olfactory bulb and depressive‐like behavior	9
Transcriptional regulation of basophil‐specific protease genes by C/EBPα, GATA2, TGF‐β signaling, and epigenetic mechanisms	9
Silica‐coated magnetic nanobeads in a flow enrichment target capture Halbach (FETCH) magnetic separation system for circulating tumor cell enrichment	9
Clinical and mechanistic insights into the roles of DDX41 in haematological malignancies	9
Front Cover	9
Front Cover	9
Molecular principles of bidirectional signalling between membranes and small GTPases	9
A quest to unravel the role of the stalk and microtubule‐binding domain of axonemal dyneins	9
Cell proliferation and cell death during whole‐body regeneration in the demosponge Halisarca dujardinii	9
Single‐dose immunisation with a multimerised SARS‐CoV‐2 receptor binding domain (RBD) induces an enhanced and protective response in mice	9
Blueprints for the scientific society of the future: how FEBS and other scientific societies will have changed 60 years from now	9
Dissecting the Ca2+ dependence of DesA1 function in Mycobacterium tuberculosis	8
The FEBS 60th anniversary writing contest—blueprints for the scientific society of tomorrow	8
Structural basis for the recognition of the S2, S5‐phosphorylated RNA polymerase II CTD by the mRNA anti‐terminator protein hSCAF4	8
Conjugative transfer of the IncN plasmid pKM101 is mediated by dynamic interactions between the TraK accessory factor and TraI	8
The sphingolipid anteome: implications for evolution of the sphingolipid metabolic pathway	8
Cell competition: emerging signaling and unsolved questions	8
Non‐negative blind deconvolution for signal processing in a CRISPR‐edited iPSC‐cardiomyocyte model of dilated cardiomyopathy	8
An update on post‐transcriptional regulation of retrotransposons	8
The Cys‐Pro motifs in the intrinsically disordered regions of the transcription factor BACH1 mediate distinct and overlapping functions upon heme binding	8
Breaking the silence around academic harassment	8
Nuclear envelope‐remodeling events as models to assess the potential role of membranes on genome stability	8
A gold revision of the Golgi Dynamics (GOLD) domain structure and associated cell functionalities	8
Structural modeling and characterization of the Mycobacterium tuberculosisMmpL3 C‐terminal domain	8
EZH2 modulates retinoic acid signaling to ensure myotube formation during development	8
Chances and challenges of long‐distance electron transfer for cellular redox reactions	8
A single evolutionarily divergent mutation determines the different FAD‐binding affinities of human and rat NQO1 due to site‐specific phosphorylation	8
EU‐LIFE charter of independent life science research institutes	8
Heme‐dependent recognition of 5‐aminolevulinate synthase by the human mitochondrial molecular chaperone ClpX	8
Azurocidin is loaded into small extracellular vesicles via its N‐linked glycosylation and promotes intravasation of renal cell carcinoma cells	8
Two phosphoenolpyruvate carboxykinases with differing biochemical properties in Chlamydomonas reinhardtii	8
Front Cover	8
Structural insights into the inhibitory mechanism of angiotensin‐I‐converting enzyme by the lactotripeptides IPP and VPP	8
A weak COPI binding motif in the cytoplasmic tail of SARS‐CoV‐2 spike glycoprotein is necessary for its cleavage, glycosylation, and localization	8
Cell–cell adhesions in embryonic stem cells regulate the stability and transcriptional activity of β‐catenin	8
Liver gene transfer for metabolite detoxification in inherited metabolic diseases	8
Interlinked bi‐stable switches govern the cell fate commitment of embryonic stem cells	8
Multiplexed imaging to reveal tissue dendritic cell spatial localisation and function	7
Regulation of epithelial‐to‐mesenchymal transition in hypoxia by the HIF‐1α network	7
Uncovering domain motif interactions using high‐throughput protein–protein interaction detection methods	7
Protein engineering of antifreeze proteins reveals that their activity scales with the area of the ice‐binding site	7
Corrigendum	7
Novel insights into autophagosome biogenesis revealed by cryo‐electron tomography	7
Mitochondrial [2Fe‐2S] ferredoxins: new functions for old dogs	7
Docking and molecular simulations reveal a quinone‐binding site on the surface of respiratory complex I	7
Promiscuous activity of β‐carotene hydroxylase CrtZ on epoxycarotenoids leads to the formation of rare carotenoids with 6‐hydroxy‐3‐keto‐ε‐ends	7
hnRNPA1 enhances FOXP3 stability to promote the differentiation and functions of regulatory T cells	7
Five problems plaguing publishing in the life sciences—and one common cause	7
Interface‐based design of the favipiravir‐binding site in SARS‐CoV‐2 RNA‐dependent RNA polymerase reveals mutations conferring resistance to chain termination	7
Corrigendum	7
Interorgan crosstalk in pancreatic islet function and pathology	7
The cell division protein ZapE is targeted by the antibiotic aztreonam to induce cell filamentation in Escherichia coli	7
Discovery of a novel siphonaxanthin biosynthetic precursor in Codium fragile that accumulates only by exposure to blue‐green light	7
Genome‐wide analysis of the mouse LIM gene family reveals its roles in regulating pathological cardiac hypertrophy	7
The ubiquitin–proteasome system and autophagy mutually interact in neurotoxin‐induced dopaminergic cell death models of Parkinson's disease	7
Hepatocyte nuclear factor HNF1A is a potential regulator in shaping the super‐enhancer landscape in colorectal cancer liver metastasis	7
Inflammasomes in epithelial innate immunity: front line warriors	7
A two‐step mechanism for the binding of the HIV‐1 MPER epitope by the 10E8 antibody onto biosensor‐supported lipid bilayers	7
Cryo‐EM structure of the full‐length Lon protease from Thermus thermophilus	7
Lipid droplets provide metabolic flexibility for cancer progression	7
The structure of COPI vesicles and regulation of vesicle turnover	7
Pseudouridines in RNAs: switching atoms means shifting paradigms	7
Membrane association of the ATG8 conjugation machinery emerges as a key regulatory feature for autophagosome biogenesis	6
A historical perspective of macroautophagy regulation by biochemical and biomechanical stimuli	6
Protein translocation in mitochondria: Sorting out the Toms, Tims, Pams, Sams and Mia	6
Solving the protein folding problem…	6
‘Friend versus foe’—does autophagy help regulate symbiotic plant–microbe interactions and can it be manipulated to improve legume cultivation?	6
‘GutFeel’: an in silico method for predicting gut health status based on the metabolic functional capabilities of the resident microbiome	6
The fusion of quantitative molecular proteomics and immune‐oncology: a step towards precision medicine in cancer therapeutics	6
Front Cover	6
Human PHOSPHO1 exhibits phosphatidylcholine‐ and phosphatidylethanolamine‐phospholipase C activities and interacts with diacylglycerol kinase δ	6
The therapeutic capacity of bone marrow MSC‐derived extracellular vesicles in Achilles tendon healing is passage‐dependent and indicated by specific glycans	6
RETRACTION: Ultraviolet B Radiation‐Induced Apoptosis in Human Keratinocytes: Cytosolic Activation of Procaspase‐8 and the Role of Bcl‐2	6
The histone H2B ubiquitination regulator Wac is essential for plasma cell differentiation	6
Phagophore closure, autophagosome maturation and autophagosome fusion during macroautophagy in the yeast Saccharomyces cerevisiae	6
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A guide for blood–brain barrier models	6
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Violaceoid F induces nuclear translocation of FOXO3a by inhibiting CRM1via a novel mechanism and suppresses HeLa cell growth	6
ICLAMP: a novel technique to explore adenosine deamination via inosine chemical labeling and affinity molecular purification	6
The structure of a haemoglobin–nanobody complex reveals human β‐subunit‐specific interactions	6
The mitotic checkpoint kinase BUB1 is a direct and actionable target of MYB in adenoid cystic carcinoma	6
Advances in multimodal mass spectrometry for single‐cell analysis and imaging enhancement	6
Spontaneous and chaperone‐assisted metal loading in the active site of protein phosphatase‐1	6
Structural insights into rapamycin‐induced oligomerization of a FRB–FKBP fusion protein	6
Age‐associated myeloid malignancies – the role of STAT3 and STAT5 in myelodysplastic syndrome and acute myeloid leukemia	6
(Poly)phenols and brain health – beyond their antioxidant capacity	6
A life‐time of hematopoietic cell function: ascent, stability, and decline	6
Reducing plastic waste in scientific protocols by 65% — practical steps for sustainable research	6
Front Cover	6
Front Cover	6
SIRT5 mutants reveal the role of conserved asparagine and glutamine residues in the NAD+‐binding pocket	6
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In situ glucosylceramide synthesis and its pharmacological inhibition analysed in cells by 13C5‐sphingosine precursor feeding and mass spectrometry	6
FBXO46 negatively regulates p53 activity by stabilizing Mdm2	6