OOIR: Observatory of International Research

Papers

(The H4-Index of Gut is 74. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Defining the key intrahepatic gene networks in HCV infection driven by sex	1549
Picking up microbial clues in early-onset colorectal cancer	1221
Finding a mate for MLCK: improving the potential for therapeutic targeting of gut permeability	852
Immunomodulation and entry inhibition: selgantolimod’s double punch against hepatitis B virus	443
Unusual history of ‘stitch’	295
Response to McAlindon’s letter	259
Unusual case of severe diarrhoea	211
Correction:P97 A patient information bundle outlining dietary advice in liver disease specific to the cost of living crisis improves patient care: ‘Looking after Your Liver for Less’	202
Perturbation of mRNA splicing in liver cancer: insights, opportunities and challenges	201
Rate of suitable cases for primary EUS-guided biliary drainage in distal malignant biliary obstruction	201
Mass cytometry-based peripheral blood analysis as a novel tool for early detection of solid tumours: a multicentre study	199
IL-3 receptor signalling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells	187
HBcrAg values may predict virological and immunological responses to pegIFN-a in NUC-suppressed HBeAg-negative chronic hepatitis B	185
Impact of margin thermal ablation after endoscopic mucosal resection of large (≥20 mm) non-pedunculated colonic polyps on long-term recurrence	183
COVID-19 and liver disease	179
Where are we with gastric cancer screening in Europe in 2024?	168
Holistic healthcare in inflammatory bowel disease: time for patient-centric approaches?	162
Third Asia-Pacific consensus recommendations on colorectal cancer screening and postpolypectomy surveillance	158
Liquid biopsy to identify Barrett’s oesophagus, dysplasia and oesophageal adenocarcinoma: theEMERALDmulticentre study	156
Innumerable nodules in all parts of the small intestine	155
Genetically proxied ketohexokinase function and risk of colorectal cancer: a Mendelian randomisation study	153
Crohn’s disease and ulcerative colitis exhibit prediagnostic antibody signatures with shared and divergent changes towards disease onset	151
Growth rates and histopathological outcomes of small (6–9 mm) colorectal polyps based on CT colonography surveillance and endoscopic removal	148
Current therapies and new developments in NASH	143
Absence of a pancreatic microbiome in intraductal papillary mucinous neoplasm	143

Autologous regulatory T-cell transfer in refractory ulcerative colitis with concomitant primary sclerosing cholangitis	142
Gut virome-colonisingOrthohepadnavirusgenus is associated with ulcerative colitis pathogenesis and induces intestinal inflammationin vivo	142
A mucus production programme promotes classical pancreatic ductal adenocarcinoma	141
Establishment of enterically transmitted hepatitis virus animal models using lipid nanoparticle-based full-length viral genome RNA delivery system	140
S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos	138
Prospective, double-blind diagnostic multicentre study of confocal laser endomicroscopy for wheat sensitivity in patients with irritable bowel syndrome	137
Methionine deficiency facilitates antitumour immunity by altering m⁶A methylation of immune checkpoint transcripts	135
Perplexing case of abdominal pain with eosinophilia and fasciitis	134
Impact of climate change on vulnerable populations	131
Need for standardised approaches to human microbiome research using the example of colorectal neoplasia research	127
Interactive enhancer hubs (iHUBs) mediate transcriptional reprogramming and adaptive resistance in pancreatic cancer	125
Correction: Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism	124
GI highlights from the literature	121
Intron-mediated enhancement of SPINK1 expression for pancreatitis therapy	121
Tiny contributors to severe obesity inside the gut	117
Reply to: Non-invasive tests and advanced chronic liver disease in NAFLD: two steps forward and one step back?	117
Shaggy white lesion with morphological changes in the oesophagus	115
From clinical trials to clinical practice: how should we design and evaluate prediction models in the care of IBD?	110
Humoral response to SARS-CoV-2 infection among liver transplant recipients	109
Host transcriptome signatures in human faecal-washes predict histological remission in patients with IBD	108
Most excess years of potential life loss among individuals with cirrhosis during the pandemic were not related to COVID-19	107
Lumen-apposing metal stents versus double-pigtail plastic stents for infected necrotising pancreatitis: more doubts than answers	101
Discovery of the pancreatic basal cell: a new candidate for an adult stem cell emerges	100
Endoscopic mucosal and submucosal cutting for long benign oesophageal strictures	97
Rare cause of obstructive jaundice	97
Integrated multimodel analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBD	96
Gastrointestinal microbiota and inflammasomes interplay in health and disease: a gut feeling	95
Selective decontamination of the digestive tract in critically ill children: fighting fire with fire or burning down the house?	95
Association between appendectomy and Parkinson’s disease from the UK Biobank	94
Definite benefits of GLP-1 receptor agonists: what is the risk of gastroparesis and lung aspiration?	93
Unveiling 8 years of duodenoscope contamination: insights from a retrospective analysis in a large tertiary care hospital	93
Time for arginine methylation: PRMT5 inhibition to advance cholangiocarcinoma treatment	93
Faecal occult blood loss accurately predicts future detection of colorectal cancer. A prognostic model	90
Reflux conditions induce E-cadherin cleavage and EMT via APE1 redox function in oesophageal adenocarcinoma	90
24-Nor-ursodeoxycholic acid improves intestinal inflammation by targeting T_H17 pathogenicity and transdifferentiation	89
Engineered anti-PDL1 with IFNα targets both immunoinhibitory and activating signals in the liver to break HBV immune tolerance	89
MicroRNA-223 attenuates hepatocarcinogenesis by blocking hypoxia-driven angiogenesis and immunosuppression	88
Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression	87
New entity of adult ultra-short coeliac disease: the first international cohort and case–control study	86
British Society of Gastroenterology guidelines on sedation in gastrointestinal endoscopy	86
Endoscopic stratification of gastric intestinal metaplasia: where are we, where do we want to go and how do we get there?	84
Tumour-intrinsic alterations and stromal matrix remodelling promote Wnt-niche independence during diffuse-type gastric cancer progression	84
SARS-CoV-2 vaccination in patients with GI and hepatobiliary carcinoma: a call for booster vaccination	83
Environmental and healthcare trade-offs between single-use and reusable gastroscopes	81
Treatment of type 2 diabetes with MASLD: new evidence for personalised medicine	81
Rethinking routine mapping biopsies in gastric intestinal metaplasia: justification for endoscopic stratification	77
GI highlights from the literature	76
Withdrawal of the British Society of Gastroenterology IBD risk grid for COVID-19 severity	76
Ebastine for the treatment of irritable bowel syndrome: old drug, new tricks?	76
APCmosaicism, not always isolated: two first-degree relatives with apparently distinctAPCmosaicism	74

Correction: Prevalence of irritable bowel syndrome and functional dyspepsia after acute gastroenteritis: systematic review and meta-analysis	74
Comparison between non-pulmonary and pulmonary immune responses in a HIV decedent who succumbed to COVID-19	74