OOIR: Observatory of International Research

Papers

(The H4-Index of Gut is 78. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
An unusual cause of oesophageal stricture	1318
Rate of suitable cases for primary EUS-guided biliary drainage in distal malignant biliary obstruction	942
Is the biogeography of the mucosa-associated microbiota a key factor affecting primary sclerosing cholangitis disease course and treatment?	723
Aspirin is associated with lower risk of pancreatic cancer and cancer-related mortality in patients with diabetes mellitus	414
Novel mouse model for studying transmural intestinal fibrosis and creeping fat formation in stricturing Crohn’s disease	363
Metabolic dysfunction-associated steatotic liver disease in children	305
Histology of subepithelial lesions (SELs) in the gastrointestinal tract-resected endoscopic: a database study of 4901 patients	301
Long-term liver-related outcomes and liver stiffness progression of statin usage in steatotic liver disease	301
Immune response and barrier dysfunction-related proteomic signatures in preclinical phase of Crohn’s disease highlight earliest events of pathogenesis	281
IL-3 receptor signalling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells	249
Over-the-scope-clips versus standard treatment in high-risk patients with acute non-variceal upper gastrointestinal bleeding: a randomised controlled trial (STING-2)	217
Longitudinal paired liver biopsies and transcriptome profiling in alcohol-associated hepatitis reveal dynamic changes in cellular senescence	209
Autoimmune gastritis may be less susceptible to cancer development thanHelicobacter pylori-related gastritis based on histological analysis	182
Screening of normal endoscopic large bowel biopsies with interpretable graph learning: a retrospective study	179
Clinical outcome of non-curative endoscopic submucosal dissection for early colorectal cancer	174
Challenge of treatment de-escalation in inflammatory bowel diseases	173
Purified oat protein can trigger acute symptoms linked to immune activation in coeliac disease patients but not histological deterioration	172
Establishment of enterically transmitted hepatitis virus animal models using lipid nanoparticle-based full-length viral genome RNA delivery system	169
A GATA6-centred gene regulatory network involving HNFs and ΔNp63 controls plasticity and immune escape in pancreatic cancer	161
Revealing and harnessing CD39 for the treatment of colorectal cancer and liver metastases by engineered T cells	160
Long-term follow-up study of necrotising pancreatitis: interventions, complications and quality of life	158
Immunoglobulin A–specific deficiency induces spontaneous inflammation specifically in the ileum	157
Escape from cell-cell and cell-matrix adhesion dependence underscores disease progression in gastric cancer organoid models	156
New AI model for neoplasia detection and characterisation in inflammatory bowel disease	155
Immune checkpoint inhibitors and the liver: balancing therapeutic benefit and adverse events	151

Stimulatory MAIT cell antigens reach the circulation and are efficiently metabolised and presented by human liver cells	149
Diet or medication in primary care patients with IBS: the DOMINO study - a randomised trial supported by the Belgian Health Care Knowledge Centre (KCE Trials Programme) and the Rome Foundation Researc	144
Over-the-scope clips versus standard treatment	143
GI highlights from the literature	141
Blood and guts	140
Omics studies in gastroenterological and hepatological patient populations: current impact and future promise exemplified by a large study of HCV-infected livers	136
Defining the key intrahepatic gene networks in HCV infection driven by sex	135
Reply to Newmanet al‘Response to epidemiology of inflammatory bowel disease in men with high-risk homosexual activity’	133
Climate change: a survey of global gastroenterology society leadership	132
GI highlights from the literature	128
Genetic analyses of treatment response in primary care IBS, a pilot study	128
Finding a mate for MLCK: improving the potential for therapeutic targeting of gut permeability	127
Consensus-based development of a causal attribution system for post-ERCP adverse events	126
Cancer as microenvironmental, systemic and environmental diseases: opportunity for transdisciplinary microbiomics science	125
Transmural intestinal fibrosis in men and mice	123
Gnotobiotic mice housing conditions critically influence the phenotype associated with transfer of faecal microbiota in a context of obesity	122
Holistic healthcare in inflammatory bowel disease: time for patient-centric approaches?	121
Picking up microbial clues in early-onset colorectal cancer	116
MAFLD, HCC and the dilemma of (changing) terminology in liver diseases	115
Considerations for peripheral blood transport and storage during large-scale multicentre metabolome research	115
Inflammation-associated gut microbiome in postacute sequelae of SARS-CoV-2 points towards new therapeutic targets	115
Antibiotic use and inflammatory bowel disease: number needed to harm?	112
Clinical advances: pregnancy in gastroenterologic and hepatic conditions	112
Going deeper: molecular inflammatory scores in IBD	112
Phase II trial of weekly erlotinib dosing to reduce duodenal polyp burden associated with familial adenomatous polyposis	109
Gastric variceal bleeding in a patient with alcohol abuse: business as usual?	106
Mixed-donor faecal microbiota transplantation was associated with increased butyrate-producing bacteria for obesity	106
Alcohol consumption and smoking dose-dependently and synergistically worsen local pancreas damage	104
COVID-19 and liver disease	101
Hepatic events associated with sodium-glucose cotransporter-2 inhibitors in patients with type 2 diabetes: a nationwide cohort study	100
Impact of delayed screening invitations on screen-detected and interval cancers in the Dutch colorectal cancer screening programme: individual-level data analysis	98
Activation of NOTCH signaling via DLL1 is mediated by APE1-redox-dependent NF-κB activation in oesophageal adenocarcinoma	97
DNA-methylation signature accurately differentiates pancreatic cancer from chronic pancreatitis in tissue and plasma	97
More than meets the eye: a strange cause of bowel obstruction and perforation	96
Genetically proxied ketohexokinase function and risk of colorectal cancer: a Mendelian randomisation study	95
Right tool for the right bleeder	94
GI highlights from the literature	93
The fundamentals: understanding the climate change crisis	92
Accuracy of measuring colorectal polyp size in pathology: a prospective study	92
Evaluating microbial determinants of donor efficacy to translate faecal microbiota transplantation from research to clinical practice	92
Beyond a liver-gut focus: the evolution of gastroenterology and hepatology in challenging the obesity and steatotic liver disease paradigm	92
Cold versus hot EMR for large duodenal adenomas	91
ForePass endoscopic bypass device for obesity and insulin resistance—metabolic treatment in a swine model	87
Relative risk rather than absolute risk reduction should be preferred to sensitise the public to preventive actions	86
Mass cytometry-based peripheral blood analysis as a novel tool for early detection of solid tumours: a multicentre study	86
Multiple inflammatory mechanisms in eosinophilic oesophagitis make it unlikely that single pathway inhibition by monoclonal biological therapies would succeed	86
Early-life diet and risk of inflammatory bowel disease: a pooled study in two Scandinavian birth cohorts	85
Function of mast cell and bile-cholangiocarcinoma interplay in cholangiocarcinoma microenvironment	84
NGS mismapping confounds the clinical interpretation of the PRSS1 p.Ala16Val (c.47C>T) variant in chronic pancreatitis	84
Towards a new era with safer µ-opiate receptor analgesia	84

Innumerable nodules in all parts of the small intestine	80
Reply to: “Acute-on-chronic liver failure in East-Asia: an underestimated issue with limited data”	80
Diabetes is the strongest risk factor of hepatic fibrosis in lean patients with non-alcoholic fatty liver disease	79
Unusual history of ‘stitch’	78
Diagnostic dilemma: sudden onset of multiple skin lesions in a patient with intestinal disease	78