Gut

Article	Citations
Defining the key intrahepatic gene networks in HCV infection driven by sex	1594
Picking up microbial clues in early-onset colorectal cancer	1295
Finding a mate for MLCK: improving the potential for therapeutic targeting of gut permeability	883
Immunomodulation and entry inhibition: selgantolimod’s double punch against hepatitis B virus	450
Unusual history of ‘stitch’	308
Response to McAlindon’s letter	276
Unusual case of severe diarrhoea	210
Correction:P97 A patient information bundle outlining dietary advice in liver disease specific to the cost of living crisis improves patient care: ‘Looking after Your Liver for Less’	209
Impact of margin thermal ablation after endoscopic mucosal resection of large (≥20 mm) non-pedunculated colonic polyps on long-term recurrence	206
Holistic healthcare in inflammatory bowel disease: time for patient-centric approaches?	193
Liquid biopsy to identify Barrett’s oesophagus, dysplasia and oesophageal adenocarcinoma: theEMERALDmulticentre study	191
Innumerable nodules in all parts of the small intestine	189
A mucus production programme promotes classical pancreatic ductal adenocarcinoma	184
Perturbation of mRNA splicing in liver cancer: insights, opportunities and challenges	177
Genetically proxied ketohexokinase function and risk of colorectal cancer: a Mendelian randomisation study	172
Crohn’s disease and ulcerative colitis exhibit prediagnostic antibody signatures with shared and divergent changes towards disease onset	172
Establishment of enterically transmitted hepatitis virus animal models using lipid nanoparticle-based full-length viral genome RNA delivery system	169
Mass cytometry-based peripheral blood analysis as a novel tool for early detection of solid tumours: a multicentre study	163
IL-3 receptor signalling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells	159
S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos	156
Prospective, double-blind diagnostic multicentre study of confocal laser endomicroscopy for wheat sensitivity in patients with irritable bowel syndrome	155
Third Asia-Pacific consensus recommendations on colorectal cancer screening and postpolypectomy surveillance	154
Growth rates and histopathological outcomes of small (6–9 mm) colorectal polyps based on CT colonography surveillance and endoscopic removal	153
Hepatocyte senescence in alcohol-associated hepatitis: epiphenomenon or disease-driving mechanism?	152
Reassessing the prophylactic effect of clip closure to prevent delayed rebleeding after colorectal endoscopic submucosal dissection	148

Absence of a pancreatic microbiome in intraductal papillary mucinous neoplasm	148
Rate of suitable cases for primary EUS-guided biliary drainage in distal malignant biliary obstruction	146
COVID-19 and liver disease	144
Where are we with gastric cancer screening in Europe in 2024?	143
HBcrAg values may predict virological and immunological responses to pegIFN-a in NUC-suppressed HBeAg-negative chronic hepatitis B	137
Gut virome-colonisingOrthohepadnavirusgenus is associated with ulcerative colitis pathogenesis and induces intestinal inflammationin vivo	137
Current therapies and new developments in NASH	132
Autologous regulatory T-cell transfer in refractory ulcerative colitis with concomitant primary sclerosing cholangitis	130
Impact of climate change on vulnerable populations	127
Perplexing case of abdominal pain with eosinophilia and fasciitis	127
Methionine deficiency facilitates antitumour immunity by altering m6A methylation of immune checkpoint transcripts	127
Time for arginine methylation: PRMT5 inhibition to advance cholangiocarcinoma treatment	122
Most excess years of potential life loss among individuals with cirrhosis during the pandemic were not related to COVID-19	122
Tumour-intrinsic alterations and stromal matrix remodelling promote Wnt-niche independence during diffuse-type gastric cancer progression	119
New entity of adult ultra-short coeliac disease: the first international cohort and case–control study	116
Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression	112
From clinical trials to clinical practice: how should we design and evaluate prediction models in the care of IBD?	109
24-Nor-ursodeoxycholic acid improves intestinal inflammation by targeting TH17 pathogenicity and transdifferentiation	108
Correction: Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism	107
GI highlights from the literature	105
Reply to: Non-invasive tests and advanced chronic liver disease in NAFLD: two steps forward and one step back?	105
Tiny contributors to severe obesity inside the gut	100
Shaggy white lesion with morphological changes in the oesophagus	100
Host transcriptome signatures in human faecal-washes predict histological remission in patients with IBD	99
Lumen-apposing metal stents versus double-pigtail plastic stents for infected necrotising pancreatitis: more doubts than answers	99
Humoral response to SARS-CoV-2 infection among liver transplant recipients	99
Discovery of the pancreatic basal cell: a new candidate for an adult stem cell emerges	98
Rare cause of obstructive jaundice	97
Endoscopic mucosal and submucosal cutting for long benign oesophageal strictures	96
Engineered anti-PDL1 with IFNα targets both immunoinhibitory and activating signals in the liver to break HBV immune tolerance	95
Reflux conditions induce E-cadherin cleavage and EMT via APE1 redox function in oesophageal adenocarcinoma	94
Faecal occult blood loss accurately predicts future detection of colorectal cancer. A prognostic model	94
Intron-mediated enhancement of SPINK1 expression for pancreatitis therapy	92
Definite benefits of GLP-1 receptor agonists: what is the risk of gastroparesis and lung aspiration?	92
Integrated multimodel analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBD	91
Gastrointestinal microbiota and inflammasomes interplay in health and disease: a gut feeling	90
Selective decontamination of the digestive tract in critically ill children: fighting fire with fire or burning down the house?	90
Interactive enhancer hubs (iHUBs) mediate transcriptional reprogramming and adaptive resistance in pancreatic cancer	88
Association between appendectomy and Parkinson’s disease from the UK Biobank	86
MicroRNA-223 attenuates hepatocarcinogenesis by blocking hypoxia-driven angiogenesis and immunosuppression	85
Unveiling 8 years of duodenoscope contamination: insights from a retrospective analysis in a large tertiary care hospital	84
Need for standardised approaches to human microbiome research using the example of colorectal neoplasia research	81
Treatment of type 2 diabetes with MASLD: new evidence for personalised medicine	80
British Society of Gastroenterology guidelines on sedation in gastrointestinal endoscopy	80
SARS-CoV-2 vaccination in patients with GI and hepatobiliary carcinoma: a call for booster vaccination	80
Environmental and healthcare trade-offs between single-use and reusable gastroscopes	78
Rethinking routine mapping biopsies in gastric intestinal metaplasia: justification for endoscopic stratification	78
Withdrawal of the British Society of Gastroenterology IBD risk grid for COVID-19 severity	76
Endoscopic stratification of gastric intestinal metaplasia: where are we, where do we want to go and how do we get there?	74
GI highlights from the literature	73

Correction: Prevalence of irritable bowel syndrome and functional dyspepsia after acute gastroenteritis: systematic review and meta-analysis	72
Ebastine for the treatment of irritable bowel syndrome: old drug, new tricks?	72
APCmosaicism, not always isolated: two first-degree relatives with apparently distinctAPCmosaicism	72
Association between inflammatory bowel disease and Alzheimer’s disease: multivariable and bidirectional Mendelian randomisation analyses	71
British Society of Gastroenterology interim framework for addressing the COVID-19-related backlog in inflammatory bowel disease colorectal cancer surveillance	71
Targeting hepatic stellate cells to combat liver fibrosis: where do we stand?	70
Impact of age, comorbidities and relevant changes on surveillance strategy of intraductal papillary mucinous neoplasms: a competing risk analysis	69
Hypophosphataemia following ferric derisomaltose and ferric carboxymaltose in patients with iron deficiency anaemia due to inflammatory bowel disease (PHOSPHARE-IBD): a randomised clinical trial	69
Correction: Revisiting the role of sphincterotomy in sphincter of oddi disorder: a critical appraisal of the RESPOnD study	69
Endoscopic papillectomy versus surgical ampullectomy for adenomas and early cancers of the papilla: a retrospective Pancreas2000/European Pancreatic Club analysis	68
Immunopathogenesis and environmental triggers in coeliac disease	68
Anticoagulation in colorectal ESD: implications for bleeding risk management	67
Targeting MS4A4A on tumour-associated macrophages restores CD8+ T-cell-mediated antitumour immunity	67
Postprandial symptoms in disorders of gut-brain interaction and their potential as a treatment target	67
Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8+T cells	64
Fasting-mimicking diet-enriched Bifidobacterium pseudolongum suppresses colorectal cancer by inducing memory CD8+ T cells	64
FSTL1 promotes liver fibrosis by reprogramming macrophage function through modulating the intracellular function of PKM2	63
GI highlights from the literature	63
Molecular portraits of patients with intrahepatic cholangiocarcinoma who diverge as rapid progressors or long survivors on chemotherapy	62
GI highlights from the literature	62
It takes two to TAM-go	61
Fatal intestinal disease: a case of recurrent lower gastrointestinal bleeding	61
Monocyte phenotypic liquid biopsy for NASH and liver fibrosis diagnosis: a new kid on the block	59
Nuclear Pirin promotes HCC by acting as a key inflammation-facilitating factor	59
Abnormal gastrointestinal motility is a major factor in explaining symptoms and a potential therapeutic target in patients with disorders of gut–brain interaction	59
Non-invasive assessment of MASH resolution	58
A black liver	58
Submucosal steroid pre-injection strategy to prevent oesophageal stricture after circumferential endoscopic submucosal dissection	57
Gastric emptying study before gastric peroral endoscopic myotomy (G-POEM): can intragastric meal distribution be a predictor of success?	57
Comparison of drugs for active eosinophilic oesophagitis: systematic review and network meta-analysis	57
Quest for HBV functional cure: what have we learnt from silencing RNAs?	56
Spatial dissection of tumour microenvironments in gastric cancers reveals the immunosuppressive crosstalk between CCL2+ fibroblasts and STAT3-activated macrophages	56
Response letter to the editor	55
Clinical relevance of biomarkers in cholangiocarcinoma: critical revision and future directions	54
MED12 loss activates endogenous retroelements to sensitise immunotherapy in pancreatic cancer	54
Unravelling the obesity paradox in MASLD patients with extrahepatic cancer	53
Porcine-derived pancreatic enzyme replacement therapy may be linked to chronic hepatitis E virus infection in cystic fibrosis lung transplant recipients	53
Gut check: can other microbes or communities phenocopyH. pylori’s early gastric pathology?	53
Prevalence of serum HBsAg <100 IU/mL in inactive chronic hepatitis B	53
Understanding the malignant potential of gastric metaplasia of the oesophagus and its relevance to Barrett’s oesophagus surveillance: individual-level data analysis	52
NFATc1 signaling drives chronic ER stress responses to promote NAFLD progression	52
National Institute for Health and Care Excellence (NICE) guidance on monitoring and management of Barrett’s oesophagus and stage I oesophageal adenocarcinoma	52
Response by Abrahami et al to letter regarding article ‘Proton pump inhibitors and risk of colorectal cancer’	51
GI highlights from the literature	51
NLRP6 deficiency enhances macrophage-mediated phagocytosis via E-Syt1 to inhibit hepatocellular carcinoma progression	51
Evaluation of proton pump inhibitors and risks of gastric cancer	50
Diagnostic dilemma: a patient with diarrhoea	50
Risk of metachronous advanced neoplasia in patients with serrated lesions depending on follow-up schedule	50
Correction:PMO-29 Switching between infliximab biosimilars: experience from two inflammatory bowel disease centres	50
Landscape of the gut mycobiome dynamics during pregnancy and its relationship with host metabolism and pregnancy health	49
Human milk oligosaccharide 2�-fucosyllactose protects against high-fat diet-induced obesity by changing intestinal mucus production, composition and degradation linked to changes in gut microbiota and	49
Targeting ER protein TXNDC5 in hepatic stellate cell mitigates liver fibrosis by repressing non-canonical TGFβ signalling	49
The Peptidoglycan Recognition Protein 1 confers immune evasive properties on pancreatic cancer stem cells	48
APCandP53mutations synergise to create a therapeutic vulnerability to NOTUM inhibition in advanced colorectal cancer	48
Human enteric nervous system progenitor transplantation improves functional responses in Hirschsprung disease patient-derived tissue	48
Assessment of the yearly carbon emission of a gastrointestinal endoscopy unit	47
Prevalence of irritable bowel syndrome and functional dyspepsia after acute gastroenteritis: systematic review and meta-analysis	47
Gut microbiota as non-invasive diagnostic and prognostic biomarkers for natural killer/T-cell lymphoma	45
IL-20 subfamily cytokines impair the oesophageal epithelial barrier by diminishing filaggrin in eosinophilic oesophagitis	45
Pericyte drives the formation of circulating tumour cell-neutrophil clusters to promote colorectal cancer metastasis	45
Autologous T cell responses to primary human colorectal cancer spheroids are enhanced by ectonucleotidase inhibition	45
Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer	45
Long-term use of proton pump inhibitors (PPIs) is associated with an increased risk of type 2 diabetes	44
Hepatic TM6SF2 activates antitumour immunity to suppress metabolic dysfunction-associated steatotic liver disease-related hepatocellular carcinoma and boosts immunotherapy	44
Combining dietary fibres to reduce intestinal gas production in patients with IBS	44
Withdrawal of antitumour necrosis factor in patients with inflammatory bowel disease in remission: a randomised placebo-controlled clinical trial of GETECCU	43
Correction: Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway	43
Dominant-negative effect of lactase missense variants: hetero-complex assembly with the wild-type enzyme impairs intracellular trafficking and digestive function	43
Combining epigenetic modulation: the next step for HCC immunotherapy?	43
Uniting the global gastroenterology community to meet the challenge of climate change and non-recyclable waste	42
Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/2	42
Interplay between diet, circulating indolepropionate concentrations and cardiometabolic health in US populations	41
NNMT enriches for AQP5+cancer stem cells to drive malignant progression in early gastric cardia adenocarcinoma	41
Single-cell sequencing unveils distinct immune microenvironments with CCR6-CCL20 crosstalk in human chronic pancreatitis	41
Fungi and cancer	40
The road to a world-unified approach to the management of patients with gastric intestinal metaplasia: a review of current guidelines	40
Cultivated human intestinal fungusCandida metapsilosisM2006B attenuates colitis by secreting acyclic sesquiterpenoids as FXR agonists	40
Targeting TL1A and DR3: the new frontier of anti-cytokine therapy in IBD	40
Synergistic association of sodium-glucose cotransporter-2 inhibitor and metformin on liver and non-liver complications in patients with type 2 diabetes mellitus and metabolic dysfunction-associated st	39
Global prevalence of non-alcoholic fatty liver disease in type 2 diabetes mellitus: an updated systematic review and meta-analysis	39

Long-term hepatitis B surface antigen response after finite treatment of ARC-520 or JNJ-3989	39
Correction:O4 Acceptability and feasibility of a multimodal early detection pilot study for liver disease in high risk groups: “Alright My Liver?”	38
Correction:Sympathetic nervous activation, mitochondrial dysfunction and outcome in acutely decompensated cirrhosis: the metabolomic prognostic models (CLIF-C MET)	37
Eosinophils: a novel therapeutic target to promote liver regeneration in acute liver injury?	37
Is HBx protein the X factor in the pathogenesis of IBD?	36
GI highlights from the literature	36
Alcohol exhibits contrasting effects on CD8+ T cells in the gut and liver in alcohol-associated liver disease	36
Is the significant risk of perioperative complications associated with radical surgery following non-curative endoscopic submucosal dissection for early colorectal cancer still acceptable?	36
Tailoring treatment to the circumstance: reasoning behind metal versus plastic drainage of pancreatic collections	36
Effectiveness of mailed outreach and patient navigation to promote HCC screening process completion: a multicentre pragmatic randomised clinical trial	35
GI snapshot: arrhythmia, dysphagia and weight loss in a 71-year-old man	35
DYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer	35
Artificial intelligence applied to ‘omics data in liver disease: towards a personalised approach for diagnosis, prognosis and treatment	35
What to do about the leaky gut	35
Trends and cross-country inequality in the incidence of GI cancers among the working-age population from 1990 to 2021: a Global Burden of Disease 2021 analysis	35
Cold versus hot snare endoscopic mucosal resection for large (≥15 mm) flat non-pedunculated colorectal polyps: a randomised controlled trial	34
Alternative splicing of viral transcripts: the dark side of HBV	34
SARS-CoV-2 Omicron variant infection was associated with higher morbidity in patients with cirrhosis	33
Estimating the environmental impact of disposable endoscopic equipment and endoscopes	33
Basal levels of microbiota-driven subclinical inflammation are associated with anastomotic leak in patients with colorectal cancer	33
Correction: Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma	33
Alterations to the duodenal microbiota are linked to gastric emptying and symptoms in functional dyspepsia	33
Variceal band ligation and carvedilol: together forever, or not?	32
Establishment of a validated central reading system for ileocolonoscopy in an academic setting	32
Precancerous nature of intestinal metaplasia with increased chance of conversion and accelerated DNA methylation	32
Vessel and tissue recognition during third-space endoscopy using a deep learning algorithm	32
Sex-based differences in prescribed medications, surgical procedures and disease-related complications in IBD	32
Antibody response to the BNT162b2 SARS-CoV-2 vaccine in paediatric patients with inflammatory bowel disease treated with anti-TNF therapy	32
Simplified Helicobacter pylori therapy for patients with penicillin allergy: a randomised controlled trial of vonoprazan-tetracycline dual therapy	31
CAF-macrophage crosstalk in tumour microenvironments governs the response to immune checkpoint blockade in gastric cancer peritoneal metastases	31
Endocytoscopy with automated multispectral intestinal barrier pathology imaging for assessment of deep healing to predict outcomes in ulcerative colitis	31
Cellular immunotherapies and immune cell depleting therapies in inflammatory bowel diseases: the next magic bullet?	31
Organoids in gastrointestinal diseases: from experimental models to clinical translation	31
Multiomics reveal unique signatures of human epiploic adipose tissue related to systemic insulin resistance	31
Maternal antibiotic exposure during pregnancy and risk of IBD in offspring: a population-based cohort study	30
British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma	30
Phenotypic CD8 T cell profiling in chronic hepatitis B to predict HBV-specific CD8 T cell susceptibility to functional restoration in vitro	30
Stool microRNA profiling— dumpster diving for a master marker?	30
Recent advances in incretin-based therapy for MASLD: from single to dual or triple incretin receptor agonists	30
Nuclear translocation of plasma membrane protein ADCY7 potentiates T cell-mediated antitumour immunity in HCC	30
Single-cell omics in inflammatory bowel disease: recent insights and future clinical applications	30
More than meets the eye: a strange cause of bowel obstruction and perforation	30
Liver stiffness thresholds to predict disease progression and clinical outcomes in bridging fibrosis and cirrhosis	30
HBV integrations reshaping genomic structures promote hepatocellular carcinoma	30
Gut microbiome and dietary fibre intake strongly associate with IgG function and maturation following SARS-CoV-2 mRNA vaccination	30
Combining ferroptosis induction with MDSC blockade renders primary tumours and metastases in liver sensitive to immune checkpoint blockade	30
Specific gut pathobionts escape antibody coating and are enriched during flares in patients with severe Crohn’s disease	30
Reply to Newmanet al‘Response to epidemiology of inflammatory bowel disease in men with high-risk homosexual activity’	29
Ferritin—a promising biomarker in MASLD	28
Porcine-derived pancreatic enzyme replacement therapy: a cause of hepatitis E virus transmission?	28
Unusual cause of abdominal pain	28
Germline mutations and pancreatic cancer risk in chronic pancreatitis	27
Correction:O11 Utilising peer support workers in hepatitis C screening in emergency departments: a pilot study	27
An unusual cause of oesophageal stricture	27
eCura and W-eCura: different scores, different populations, same goal	27
Over-the-scope-clips versus standard treatment in high-risk patients with acute non-variceal upper gastrointestinal bleeding: a randomised controlled trial (STING-2)	27
Reconsidering statins in MASLD: beyond cardiovascular protection to multisystem benefit	27
Correction:Residual SARS-CoV-2 viral antigens detected in GI and hepatic tissues from five recovered patients with COVID-19	27
Key metabolomic alterations are associated with ulcerative colitis disease state and activity: a validation analysis	26
Patient-reported experience of colonoscopy in Italy: a multicentre prospective observational study	26
Adherent-invasive Escherichia coli in Crohn’s disease: the 25th anniversary	26
MAFLD, HCC and the dilemma of (changing) terminology in liver diseases	26
Post-acute COVID-19 syndrome and gut dysbiosis linger beyond 1 year after SARS-CoV-2 clearance	26
Omega-3 polyunsaturated fatty acids: moving towards precision use for prevention and treatment of colorectal cancer	26
Gnotobiotic mice housing conditions critically influence the phenotype associated with transfer of faecal microbiota in a context of obesity	26
Is the biogeography of the mucosa-associated microbiota a key factor affecting primary sclerosing cholangitis disease course and treatment?	26
Presenilins: the hidden guardians of gut health in Alzheimers disease	26
Toxic microbiome and progression of chronic kidney disease: insights from a longitudinal CKD-microbiome study	26
Clinical outcome of non-curative endoscopic submucosal dissection for early colorectal cancer	25
Purified oat protein can trigger acute symptoms linked to immune activation in coeliac disease patients but not histological deterioration	25
CRIP1 fosters MDSC trafficking and resets tumour microenvironment via facilitating NF-κB/p65 nuclear translocation in pancreatic ductal adenocarcinoma	25
Smoking affects gut immune system of patients with inflammatory bowel diseases by modulating metabolomic profiles and mucosal microbiota	25
Accuracy of measuring colorectal polyp size in pathology: a prospective study	25
Stressed hepatocyte sustains alcohol-associated hepatitis progression by producing leukocyte cell-derived chemotaxin 2	25
Performance of the China-CLIF framework in acute-on-chronic liver failure: a multicohort study across all aetiologies	25
Response to the letter to the editor ‘revisiting lipid dysregulation in colorectal cancer: critical appraisal of pro-inflammatory bias and therapeutic implications’	25
Purastat post-EMR: unresolved questions from the PURPLE trial	25
Inhibition of YTHDF1 by salvianolic acid overcomes gluten-induced intestinal inflammation	25
DNA-methylation signature accurately differentiates pancreatic cancer from chronic pancreatitis in tissue and plasma	24
Intravital imaging: dynamic insights into liver immunity in health and disease	24
Faecal immunochemical testing (FIT) in patients with signs or symptoms of suspected colorectal cancer (CRC): a joint guideline from the Association of Coloproctology of Great Britain and Ireland (ACPG	24
Genetic and transcriptomic landscape of colonic diverticulosis	24
Cold versus hot EMR for large duodenal adenomas	24
Patient selection for urgent endoscopic retrograde cholangio-pancreatography by endoscopic ultrasound in predicted severe acute biliary pancreatitis (APEC-2): a multicentre prospective study	24
Short-chain fatty acids in patients with severe acute pancreatitis: friend or foe?	24
Long-term liver-related outcomes and liver stiffness progression of statin usage in steatotic liver disease	24
Mapping the human gut mycobiome in middle-aged and elderly adults: multiomics insights and implications for host metabolic health	24
Efficacy of biological therapies and small molecules in moderate to severe ulcerative colitis: systematic review and network meta-analysis	24
GI highlights from the literature	23
NoH. pylori, no adenocarcinoma for patients with autoimmune gastritis	23
World Gastroenterology Organisation -Gutcommentary series on digestive health and climate change	23
Gut microbiota and atherosclerosis	23
CNNM4: a ferroptotic vulnerability in cholangiocarcinoma	23
Strengths and limitations of AlphaMissense inCPA1missense variant classification	23
Response to: Correspondence on "PICaSSO Histologic Remission Index (PHRI) in ulcerative colitis: development of a novel simplified histological score for monitoring mucosal healing and predicting clin	23