Gut

Papers
(The TQCC of Gut is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
Growth rates and histopathological outcomes of small (6–9 mm) colorectal polyps based on CT colonography surveillance and endoscopic removal1433
Defining the key intrahepatic gene networks in HCV infection driven by sex1072
Picking up microbial clues in early-onset colorectal cancer775
Finding a mate for MLCK: improving the potential for therapeutic targeting of gut permeability431
Genetically proxied ketohexokinase function and risk of colorectal cancer: a Mendelian randomisation study306
Innumerable nodules in all parts of the small intestine273
Immunomodulation and entry inhibition: selgantolimod’s double punch against hepatitis B virus213
Unusual history of ‘stitch’196
Response to McAlindon’s letter192
Unusual case of severe diarrhoea190
Correction:P97 A patient information bundle outlining dietary advice in liver disease specific to the cost of living crisis improves patient care: ‘Looking after Your Liver for Less’190
Rate of suitable cases for primary EUS-guided biliary drainage in distal malignant biliary obstruction184
Prospective, double-blind diagnostic multicentre study of confocal laser endomicroscopy for wheat sensitivity in patients with irritable bowel syndrome174
Where are we with gastric cancer screening in Europe in 2024?171
IL-3 receptor signalling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells169
Absence of a pancreatic microbiome in intraductal papillary mucinous neoplasm164
Perturbation of mRNA splicing in liver cancer: insights, opportunities and challenges163
HBcrAg values may predict virological and immunological responses to pegIFN-a in NUC-suppressed HBeAg-negative chronic hepatitis B161
Automated sizing of colorectal polyps using computer vision160
Impact of margin thermal ablation after endoscopic mucosal resection of large (≥20 mm) non-pedunculated colonic polyps on long-term recurrence156
A mucus production programme promotes classical pancreatic ductal adenocarcinoma154
COVID-19 and liver disease151
Methionine deficiency facilitates antitumour immunity by altering m6A methylation of immune checkpoint transcripts145
Third Asia-Pacific consensus recommendations on colorectal cancer screening and postpolypectomy surveillance145
Liquid biopsy to identify Barrett’s oesophagus, dysplasia and oesophageal adenocarcinoma: theEMERALDmulticentre study145
S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos144
Holistic healthcare in inflammatory bowel disease: time for patient-centric approaches?142
Autologous regulatory T-cell transfer in refractory ulcerative colitis with concomitant primary sclerosing cholangitis135
Current therapies and new developments in NASH134
Gut virome-colonisingOrthohepadnavirusgenus is associated with ulcerative colitis pathogenesis and induces intestinal inflammationin vivo134
Mass cytometry-based peripheral blood analysis as a novel tool for early detection of solid tumours: a multicentre study133
Establishment of enterically transmitted hepatitis virus animal models using lipid nanoparticle-based full-length viral genome RNA delivery system133
Definite benefits of GLP-1 receptor agonists: what is the risk of gastroparesis and lung aspiration?132
Impact of climate change on vulnerable populations129
Perplexing case of abdominal pain with eosinophilia and fasciitis129
24-Nor-ursodeoxycholic acid improves intestinal inflammation by targeting TH17 pathogenicity and transdifferentiation129
Correction: Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism127
Intron-mediated enhancement of SPINK1 expression for pancreatitis therapy125
Tumour-intrinsic alterations and stromal matrix remodelling promote Wnt-niche independence during diffuse-type gastric cancer progression124
Interactive enhancer hubs (iHUBs) mediate transcriptional reprogramming and adaptive resistance in pancreatic cancer124
GI highlights from the literature122
Tiny contributors to severe obesity inside the gut120
Reply to: Non-invasive tests and advanced chronic liver disease in NAFLD: two steps forward and one step back?120
Shaggy white lesion with morphological changes in the oesophagus120
From clinical trials to clinical practice: how should we design and evaluate prediction models in the care of IBD?113
Humoral response to SARS-CoV-2 infection among liver transplant recipients110
Host transcriptome signatures in human faecal-washes predict histological remission in patients with IBD109
Most excess years of potential life loss among individuals with cirrhosis during the pandemic were not related to COVID-19106
GI highlights from the literature105
Lumen-apposing metal stents versus double-pigtail plastic stents for infected necrotising pancreatitis: more doubts than answers105
Discovery of the pancreatic basal cell: a new candidate for an adult stem cell emerges105
Time for arginine methylation: PRMT5 inhibition to advance cholangiocarcinoma treatment105
Need for standardised approaches to human microbiome research using the example of colorectal neoplasia research102
Association between appendectomy and Parkinson’s disease from the UK Biobank99
Reflux conditions induce E-cadherin cleavage and EMT via APE1 redox function in oesophageal adenocarcinoma97
Rare cause of obstructive jaundice97
Integrated multimodel analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBD95
Unveiling 8 years of duodenoscope contamination: insights from a retrospective analysis in a large tertiary care hospital94
Engineered anti-PDL1 with IFNα targets both immunoinhibitory and activating signals in the liver to break HBV immune tolerance92
Gastrointestinal microbiota and inflammasomes interplay in health and disease: a gut feeling89
New entity of adult ultra-short coeliac disease: the first international cohort and case–control study89
Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression89
Selective decontamination of the digestive tract in critically ill children: fighting fire with fire or burning down the house?89
British Society of Gastroenterology guidelines on sedation in gastrointestinal endoscopy88
Faecal occult blood loss accurately predicts future detection of colorectal cancer. A prognostic model87
Sodium+/taurocholate cotransporting polypeptide as target therapy for liver fibrosis85
MicroRNA-223 attenuates hepatocarcinogenesis by blocking hypoxia-driven angiogenesis and immunosuppression85
APCmosaicism, not always isolated: two first-degree relatives with apparently distinctAPCmosaicism84
Endoscopic stratification of gastric intestinal metaplasia: where are we, where do we want to go and how do we get there?83
SARS-CoV-2 vaccination in patients with GI and hepatobiliary carcinoma: a call for booster vaccination83
Environmental and healthcare trade-offs between single-use and reusable gastroscopes81
Treatment of type 2 diabetes with MASLD: new evidence for personalised medicine81
Rethinking routine mapping biopsies in gastric intestinal metaplasia: justification for endoscopic stratification80
Withdrawal of the British Society of Gastroenterology IBD risk grid for COVID-19 severity80
Fasting-mimicking diet-enrichedBifidobacterium pseudolongumsuppresses colorectal cancer by inducing memory CD8+T cells80
Association between inflammatory bowel disease and Alzheimer’s disease: multivariable and bidirectional Mendelian randomisation analyses78
GI highlights from the literature76
Targeting hepatic stellate cells to combat liver fibrosis: where do we stand?76
Ebastine for the treatment of irritable bowel syndrome: old drug, new tricks?74
Comparison between non-pulmonary and pulmonary immune responses in a HIV decedent who succumbed to COVID-1973
British Society of Gastroenterology interim framework for addressing the COVID-19-related backlog in inflammatory bowel disease colorectal cancer surveillance73
Correction: Prevalence of irritable bowel syndrome and functional dyspepsia after acute gastroenteritis: systematic review and meta-analysis72
Unannotated small RNA clusters associated with circulating extracellular vesicles detect early stage liver cancer71
Impact of age, comorbidities and relevant changes on surveillance strategy of intraductal papillary mucinous neoplasms: a competing risk analysis70
Dietary fibres and IBS: translating functional characteristics to clinical value in the era of personalised medicine68
FSTL1 promotes liver fibrosis by reprogramming macrophage function through modulating the intracellular function of PKM267
Endoscopic papillectomy versus surgical ampullectomy for adenomas and early cancers of the papilla: a retrospective Pancreas2000/European Pancreatic Club analysis66
Immunopathogenesis and environmental triggers in coeliac disease65
Targeting MS4A4A on tumour-associated macrophages restores CD8+ T-cell-mediated antitumour immunity65
Hypophosphataemia following ferric derisomaltose and ferric carboxymaltose in patients with iron deficiency anaemia due to inflammatory bowel disease (PHOSPHARE-IBD): a randomised clinical trial65
Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8+T cells65
Postprandial symptoms in disorders of gut-brain interaction and their potential as a treatment target64
GI highlights from the literature63
Submucosal steroid pre-injection strategy to prevent oesophageal stricture after circumferential endoscopic submucosal dissection63
GI highlights from the literature63
Molecular portraits of patients with intrahepatic cholangiocarcinoma who diverge as rapid progressors or long survivors on chemotherapy62
Gut check: can other microbes or communities phenocopyH. pylori’s early gastric pathology?61
Fatal intestinal disease: a case of recurrent lower gastrointestinal bleeding61
It takes two to TAM-go60
Clinical relevance of biomarkers in cholangiocarcinoma: critical revision and future directions60
Response letter to the editor59
Abnormal gastrointestinal motility is a major factor in explaining symptoms and a potential therapeutic target in patients with disorders of gut–brain interaction58
National Institute for Health and Care Excellence (NICE) guidance on monitoring and management of Barrett’s oesophagus and stage I oesophageal adenocarcinoma58
Monocyte phenotypic liquid biopsy for NASH and liver fibrosis diagnosis: a new kid on the block58
Non-invasive assessment of MASH resolution58
Porcine-derived pancreatic enzyme replacement therapy may be linked to chronic hepatitis E virus infection in cystic fibrosis lung transplant recipients57
Unravelling the obesity paradox in MASLD patients with extrahepatic cancer56
Spatial dissection of tumour microenvironments in gastric cancers reveals the immunosuppressive crosstalk betweenCCL2+fibroblasts andSTAT3-activated macrophages56
Comparison of drugs for active eosinophilic oesophagitis: systematic review and network meta-analysis56
Quest for HBV functional cure: what have we learnt from silencing RNAs?55
NFATc1 signaling drives chronic ER stress responses to promote NAFLD progression55
Gastric emptying study before gastric peroral endoscopic myotomy (G-POEM): can intragastric meal distribution be a predictor of success?55
Understanding the malignant potential of gastric metaplasia of the oesophagus and its relevance to Barrett’s oesophagus surveillance: individual-level data analysis54
Human enteric nervous system progenitor transplantation improves functional responses in Hirschsprung disease patient-derived tissue53
MED12 loss activates endogenous retroelements to sensitise immunotherapy in pancreatic cancer53
A black liver53
Diagnostic dilemma: a patient with diarrhoea52
GI highlights from the literature52
Response by Abrahami et al to letter regarding article ‘Proton pump inhibitors and risk of colorectal cancer’52
Combining epigenetic modulation: the next step for HCC immunotherapy?51
Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/251
Correction:PMO-29 Switching between infliximab biosimilars: experience from two inflammatory bowel disease centres50
Combining dietary fibres to reduce intestinal gas production in patients with IBS50
Risk of metachronous advanced neoplasia in patients with serrated lesions depending on follow-up schedule50
Long-term use of proton pump inhibitors (PPIs) is associated with an increased risk of type 2 diabetes49
Synergistic association of sodium-glucose cotransporter-2 inhibitor and metformin on liver and non-liver complications in patients with type 2 diabetes mellitus and metabolic dysfunction-associated st49
APCandP53mutations synergise to create a therapeutic vulnerability to NOTUM inhibition in advanced colorectal cancer49
Evaluation of proton pump inhibitors and risks of gastric cancer49
IL-20 subfamily cytokines impair the oesophageal epithelial barrier by diminishing filaggrin in eosinophilic oesophagitis48
Autologous T cell responses to primary human colorectal cancer spheroids are enhanced by ectonucleotidase inhibition48
Uniting the global gastroenterology community to meet the challenge of climate change and non-recyclable waste48
Long-term hepatitis B surface antigen response after finite treatment of ARC-520 or JNJ-398947
Withdrawal of antitumour necrosis factor in patients with inflammatory bowel disease in remission: a randomised placebo-controlled clinical trial of GETECCU47
Interplay between diet, circulating indolepropionate concentrations and cardiometabolic health in US populations47
Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer47
Dominant-negative effect of lactase missense variants: hetero-complex assembly with the wild-type enzyme impairs intracellular trafficking and digestive function47
Landscape of the gut mycobiome dynamics during pregnancy and its relationship with host metabolism and pregnancy health46
Human milk oligosaccharide 2�-fucosyllactose protects against high-fat diet-induced obesity by changing intestinal mucus production, composition and degradation linked to changes in gut microbiota and46
Targeting ER protein TXNDC5 in hepatic stellate cell mitigates liver fibrosis by repressing non-canonical TGFβ signalling46
Gut microbiota as non-invasive diagnostic and prognostic biomarkers for natural killer/T-cell lymphoma46
Assessment of the yearly carbon emission of a gastrointestinal endoscopy unit45
Hepatic TM6SF2 activates antitumour immunity to suppress metabolic dysfunction-associated steatotic liver disease-related hepatocellular carcinoma and boosts immunotherapy45
Correction: Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway45
Targeting TL1A and DR3: the new frontier of anti-cytokine therapy in IBD45
Prevalence of irritable bowel syndrome and functional dyspepsia after acute gastroenteritis: systematic review and meta-analysis44
The Peptidoglycan Recognition Protein 1 confers immune evasive properties on pancreatic cancer stem cells44
Single-cell sequencing unveils distinct immune microenvironments with CCR6-CCL20 crosstalk in human chronic pancreatitis44
NNMT enriches for AQP5+cancer stem cells to drive malignant progression in early gastric cardia adenocarcinoma44
Cultivated human intestinal fungusCandida metapsilosisM2006B attenuates colitis by secreting acyclic sesquiterpenoids as FXR agonists43
Fungi and cancer43
Global prevalence of non-alcoholic fatty liver disease in type 2 diabetes mellitus: an updated systematic review and meta-analysis42
Sex-based differences in prescribed medications, surgical procedures and disease-related complications in IBD41
The road to a world-unified approach to the management of patients with gastric intestinal metaplasia: a review of current guidelines41
Establishment of a validated central reading system for ileocolonoscopy in an academic setting40
GI snapshot: arrhythmia, dysphagia and weight loss in a 71-year-old man40
Correction:O4 Acceptability and feasibility of a multimodal early detection pilot study for liver disease in high risk groups: “Alright My Liver?”40
GI highlights from the literature40
Is HBx protein the X factor in the pathogenesis of IBD?40
Eosinophils: a novel therapeutic target to promote liver regeneration in acute liver injury?40
Is the significant risk of perioperative complications associated with radical surgery following non-curative endoscopic submucosal dissection for early colorectal cancer still acceptable?40
Specific gut pathobionts escape antibody coating and are enriched during flares in patients with severe Crohn’s disease40
Correction:Sympathetic nervous activation, mitochondrial dysfunction and outcome in acutely decompensated cirrhosis: the metabolomic prognostic models (CLIF-C MET)40
Tailoring treatment to the circumstance: reasoning behind metal versus plastic drainage of pancreatic collections39
Single-cell omics in inflammatory bowel disease: recent insights and future clinical applications38
Precancerous nature of intestinal metaplasia with increased chance of conversion and accelerated DNA methylation38
Simplified Helicobacter pylori therapy for patients with penicillin allergy: a randomised controlled trial of vonoprazan-tetracycline dual therapy38
Alcohol exhibits contrasting effects on CD8+T cells in the gut and liver in alcohol-associated liver disease37
Nuclear translocation of plasma membrane protein ADCY7 potentiates T cell-mediated antitumour immunity in HCC37
SARS-CoV-2 Omicron variant infection was associated with higher morbidity in patients with cirrhosis37
Gut microbiome and dietary fibre intake strongly associate with IgG function and maturation following SARS-CoV-2 mRNA vaccination36
Vessel and tissue recognition during third-space endoscopy using a deep learning algorithm35
Trends and cross-country inequality in the incidence of GI cancers among the working-age population from 1990 to 2021: a Global Burden of Disease 2021 analysis35
Variceal band ligation and carvedilol: together forever, or not?35
Correction: Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma34
Maternal antibiotic exposure during pregnancy and risk of IBD in offspring: a population-based cohort study34
Estimating the environmental impact of disposable endoscopic equipment and endoscopes33
Multiomics reveal unique signatures of human epiploic adipose tissue related to systemic insulin resistance33
Effectiveness of mailed outreach and patient navigation to promote HCC screening process completion: a multicentre pragmatic randomised clinical trial33
Cellular immunotherapies and immune cell depleting therapies in inflammatory bowel diseases: the next magic bullet?33
British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma33
Liver stiffness thresholds to predict disease progression and clinical outcomes in bridging fibrosis and cirrhosis33
Basal levels of microbiota-driven subclinical inflammation are associated with anastomotic leak in patients with colorectal cancer33
Endocytoscopy with automated multispectral intestinal barrier pathology imaging for assessment of deep healing to predict outcomes in ulcerative colitis33
DYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer33
Artificial intelligence applied to ‘omics data in liver disease: towards a personalised approach for diagnosis, prognosis and treatment33
Organoids in gastrointestinal diseases: from experimental models to clinical translation32
Cold versus hot snare endoscopic mucosal resection for large (≥15 mm) flat non-pedunculated colorectal polyps: a randomised controlled trial32
Integrated analysis of the faecal metagenome and serum metabolome reveals the role of gut microbiome-associated metabolites in the detection of colorectal cancer and adenoma32
Antibody response to the BNT162b2 SARS-CoV-2 vaccine in paediatric patients with inflammatory bowel disease treated with anti-TNF therapy32
Maternal obesity, pregnancy weight gain, and birth weight and risk of colorectal cancer32
CAF-macrophage crosstalk in tumour microenvironments governs the response to immune checkpoint blockade in gastric cancer peritoneal metastases31
Alterations to the duodenal microbiota are linked to gastric emptying and symptoms in functional dyspepsia31
Recent advances in incretin-based therapy for MASLD: from single to dual or triple incretin receptor agonists31
HBV integrations reshaping genomic structures promote hepatocellular carcinoma31
Alternative splicing of viral transcripts: the dark side of HBV30
Gnotobiotic mice housing conditions critically influence the phenotype associated with transfer of faecal microbiota in a context of obesity30
Phenotypic CD8 T cell profiling in chronic hepatitis B to predict HBV-specific CD8 T cell susceptibility to functional restoration in vitro30
Combining ferroptosis induction with MDSC blockade renders primary tumours and metastases in liver sensitive to immune checkpoint blockade30
Reply to Newmanet al‘Response to epidemiology of inflammatory bowel disease in men with high-risk homosexual activity’30
What to do about the leaky gut30
More than meets the eye: a strange cause of bowel obstruction and perforation30
Stool microRNA profiling— dumpster diving for a master marker?30
Unusual cause of abdominal pain29
Intravital imaging: dynamic insights into liver immunity in health and disease29
Suppressor CD4+T cells expressing HLA-G are expanded in the peripheral blood from patients with acute decompensation of cirrhosis29
Correction:O11 Utilising peer support workers in hepatitis C screening in emergency departments: a pilot study29
An unusual cause of oesophageal stricture29
Proton pump inhibitors and gastric cancer: a population-based cohort study29
Pancreatic cancer surveillance and its ongoing challenges: is it time to refine our eligibility criteria?29
Purified oat protein can trigger acute symptoms linked to immune activation in coeliac disease patients but not histological deterioration29
eCura and W-eCura: different scores, different populations, same goal29
Porcine-derived pancreatic enzyme replacement therapy: a cause of hepatitis E virus transmission?29
Ferritin—a promising biomarker in MASLD29
Correction:Residual SARS-CoV-2 viral antigens detected in GI and hepatic tissues from five recovered patients with COVID-1929
Germline mutations and pancreatic cancer risk in chronic pancreatitis29
MAFLD, HCC and the dilemma of (changing) terminology in liver diseases28
Key metabolomic alterations are associated with ulcerative colitis disease state and activity: a validation analysis28
Is the biogeography of the mucosa-associated microbiota a key factor affecting primary sclerosing cholangitis disease course and treatment?28
Inhibition of YTHDF1 by salvianolic acid overcomes gluten-induced intestinal inflammation28
Clinical outcome of non-curative endoscopic submucosal dissection for early colorectal cancer27
Presenilins: the hidden guardians of gut health in Alzheimers disease27
Purastat post-EMR: unresolved questions from the PURPLE trial27
GM-CSF drives myelopoiesis, recruitment and polarisation of tumour-associated macrophages in cholangiocarcinoma and systemic blockade facilitates antitumour immunity26
Cold versus hot EMR for large duodenal adenomas26
Stressed hepatocyte sustains alcohol-associated hepatitis progression by producing leukocyte cell-derived chemotaxin 226
Over-the-scope-clips versus standard treatment in high-risk patients with acute non-variceal upper gastrointestinal bleeding: a randomised controlled trial (STING-2)26
Genetic and transcriptomic landscape of colonic diverticulosis26
Omega-3 polyunsaturated fatty acids: moving towards precision use for prevention and treatment of colorectal cancer26
Accuracy of measuring colorectal polyp size in pathology: a prospective study26
Efficacy of biological therapies and small molecules in moderate to severe ulcerative colitis: systematic review and network meta-analysis25
DNA-methylation signature accurately differentiates pancreatic cancer from chronic pancreatitis in tissue and plasma25
Long-term liver-related outcomes and liver stiffness progression of statin usage in steatotic liver disease25
Mapping the human gut mycobiome in middle-aged and elderly adults: multiomics insights and implications for host metabolic health25
Patient-reported experience of colonoscopy in Italy: a multicentre prospective observational study25
Patient selection for urgent endoscopic retrograde cholangio-pancreatography by endoscopic ultrasound in predicted severe acute biliary pancreatitis (APEC-2): a multicentre prospective study25
Faecal immunochemical testing (FIT) in patients with signs or symptoms of suspected colorectal cancer (CRC): a joint guideline from the Association of Coloproctology of Great Britain and Ireland (ACPG25
Post-acute COVID-19 syndrome and gut dysbiosis linger beyond 1 year after SARS-CoV-2 clearance24
Short-chain fatty acids in patients with severe acute pancreatitis: friend or foe?24
Correspondence to proton pump inhibitors and risk of colorectal cancer24
Global prevalence of ultra-short coeliac disease (USCD): the first systematic review and meta-analysis24
Correction:Growth differentiation factor 11 attenuates liver fibrosis via expansion of liver progenitor cells24
Response to: Correspondence on "PICaSSO Histologic Remission Index (PHRI) in ulcerative colitis: development of a novel simplified histological score for monitoring mucosal healing and predicting clin24
CRIP1 fosters MDSC trafficking and resets tumour microenvironment via facilitating NF-κB/p65 nuclear translocation in pancreatic ductal adenocarcinoma24
Large proximal gastric GIST tumours: downsizing by imatinib and subsequent endoresection24
SPHINX, a Guardian of Wisdom24
Axon guidance cue SEMA3A promotes the aggressive phenotype of basal-like PDAC23
Two waves of coeliac disease incidence in Sweden: a nationwide population-based cohort study from 1990 to 201523
Microbiota-induced S100A11-RAGE axis underlies immune evasion in right-sided colon adenomas and is a therapeutic target to boost anti-PD1 efficacy23
Measuring size of smaller colorectal polyps using a virtual scale function during endoscopies23
Production and possible reduction of greenhouse gases produced during GI endoscopy activity: a systematic review of available literature23
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