Gut

Article	Citations
An unusual cause of oesophageal stricture	1318
Rate of suitable cases for primary EUS-guided biliary drainage in distal malignant biliary obstruction	942
Is the biogeography of the mucosa-associated microbiota a key factor affecting primary sclerosing cholangitis disease course and treatment?	723
Aspirin is associated with lower risk of pancreatic cancer and cancer-related mortality in patients with diabetes mellitus	414
Novel mouse model for studying transmural intestinal fibrosis and creeping fat formation in stricturing Crohn’s disease	363
Metabolic dysfunction-associated steatotic liver disease in children	305
Histology of subepithelial lesions (SELs) in the gastrointestinal tract-resected endoscopic: a database study of 4901 patients	301
Long-term liver-related outcomes and liver stiffness progression of statin usage in steatotic liver disease	301
Immune response and barrier dysfunction-related proteomic signatures in preclinical phase of Crohn’s disease highlight earliest events of pathogenesis	281
IL-3 receptor signalling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells	249
Over-the-scope-clips versus standard treatment in high-risk patients with acute non-variceal upper gastrointestinal bleeding: a randomised controlled trial (STING-2)	217
Longitudinal paired liver biopsies and transcriptome profiling in alcohol-associated hepatitis reveal dynamic changes in cellular senescence	209
Autoimmune gastritis may be less susceptible to cancer development thanHelicobacter pylori-related gastritis based on histological analysis	182
Screening of normal endoscopic large bowel biopsies with interpretable graph learning: a retrospective study	179
Clinical outcome of non-curative endoscopic submucosal dissection for early colorectal cancer	174
Challenge of treatment de-escalation in inflammatory bowel diseases	173
Purified oat protein can trigger acute symptoms linked to immune activation in coeliac disease patients but not histological deterioration	172
Establishment of enterically transmitted hepatitis virus animal models using lipid nanoparticle-based full-length viral genome RNA delivery system	169
A GATA6-centred gene regulatory network involving HNFs and ΔNp63 controls plasticity and immune escape in pancreatic cancer	161
Revealing and harnessing CD39 for the treatment of colorectal cancer and liver metastases by engineered T cells	160
Long-term follow-up study of necrotising pancreatitis: interventions, complications and quality of life	158
Immunoglobulin A–specific deficiency induces spontaneous inflammation specifically in the ileum	157
Escape from cell-cell and cell-matrix adhesion dependence underscores disease progression in gastric cancer organoid models	156
New AI model for neoplasia detection and characterisation in inflammatory bowel disease	155
Immune checkpoint inhibitors and the liver: balancing therapeutic benefit and adverse events	151

Stimulatory MAIT cell antigens reach the circulation and are efficiently metabolised and presented by human liver cells	149
Diet or medication in primary care patients with IBS: the DOMINO study - a randomised trial supported by the Belgian Health Care Knowledge Centre (KCE Trials Programme) and the Rome Foundation Researc	144
Over-the-scope clips versus standard treatment	143
GI highlights from the literature	141
Blood and guts	140
Omics studies in gastroenterological and hepatological patient populations: current impact and future promise exemplified by a large study of HCV-infected livers	136
Defining the key intrahepatic gene networks in HCV infection driven by sex	135
Reply to Newmanet al‘Response to epidemiology of inflammatory bowel disease in men with high-risk homosexual activity’	133
Climate change: a survey of global gastroenterology society leadership	132
GI highlights from the literature	128
Genetic analyses of treatment response in primary care IBS, a pilot study	128
Finding a mate for MLCK: improving the potential for therapeutic targeting of gut permeability	127
Consensus-based development of a causal attribution system for post-ERCP adverse events	126
Cancer as microenvironmental, systemic and environmental diseases: opportunity for transdisciplinary microbiomics science	125
Transmural intestinal fibrosis in men and mice	123
Gnotobiotic mice housing conditions critically influence the phenotype associated with transfer of faecal microbiota in a context of obesity	122
Holistic healthcare in inflammatory bowel disease: time for patient-centric approaches?	121
Picking up microbial clues in early-onset colorectal cancer	116
Considerations for peripheral blood transport and storage during large-scale multicentre metabolome research	115
Inflammation-associated gut microbiome in postacute sequelae of SARS-CoV-2 points towards new therapeutic targets	115
MAFLD, HCC and the dilemma of (changing) terminology in liver diseases	115
Clinical advances: pregnancy in gastroenterologic and hepatic conditions	112
Going deeper: molecular inflammatory scores in IBD	112
Antibiotic use and inflammatory bowel disease: number needed to harm?	112
Phase II trial of weekly erlotinib dosing to reduce duodenal polyp burden associated with familial adenomatous polyposis	109
Mixed-donor faecal microbiota transplantation was associated with increased butyrate-producing bacteria for obesity	106
Gastric variceal bleeding in a patient with alcohol abuse: business as usual?	106
Alcohol consumption and smoking dose-dependently and synergistically worsen local pancreas damage	104
COVID-19 and liver disease	101
Hepatic events associated with sodium-glucose cotransporter-2 inhibitors in patients with type 2 diabetes: a nationwide cohort study	100
Impact of delayed screening invitations on screen-detected and interval cancers in the Dutch colorectal cancer screening programme: individual-level data analysis	98
DNA-methylation signature accurately differentiates pancreatic cancer from chronic pancreatitis in tissue and plasma	97
Activation of NOTCH signaling via DLL1 is mediated by APE1-redox-dependent NF-κB activation in oesophageal adenocarcinoma	97
More than meets the eye: a strange cause of bowel obstruction and perforation	96
Genetically proxied ketohexokinase function and risk of colorectal cancer: a Mendelian randomisation study	95
Right tool for the right bleeder	94
GI highlights from the literature	93
The fundamentals: understanding the climate change crisis	92
Accuracy of measuring colorectal polyp size in pathology: a prospective study	92
Evaluating microbial determinants of donor efficacy to translate faecal microbiota transplantation from research to clinical practice	92
Beyond a liver-gut focus: the evolution of gastroenterology and hepatology in challenging the obesity and steatotic liver disease paradigm	92
Cold versus hot EMR for large duodenal adenomas	91
ForePass endoscopic bypass device for obesity and insulin resistance—metabolic treatment in a swine model	87
Relative risk rather than absolute risk reduction should be preferred to sensitise the public to preventive actions	86
Mass cytometry-based peripheral blood analysis as a novel tool for early detection of solid tumours: a multicentre study	86
Multiple inflammatory mechanisms in eosinophilic oesophagitis make it unlikely that single pathway inhibition by monoclonal biological therapies would succeed	86
Early-life diet and risk of inflammatory bowel disease: a pooled study in two Scandinavian birth cohorts	85
Function of mast cell and bile-cholangiocarcinoma interplay in cholangiocarcinoma microenvironment	84
NGS mismapping confounds the clinical interpretation of the PRSS1 p.Ala16Val (c.47C>T) variant in chronic pancreatitis	84
Towards a new era with safer µ-opiate receptor analgesia	84

Innumerable nodules in all parts of the small intestine	80
Reply to: “Acute-on-chronic liver failure in East-Asia: an underestimated issue with limited data”	80
Diabetes is the strongest risk factor of hepatic fibrosis in lean patients with non-alcoholic fatty liver disease	79
Unusual history of ‘stitch’	78
Diagnostic dilemma: sudden onset of multiple skin lesions in a patient with intestinal disease	78
Patient selection for urgent endoscopic retrograde cholangio-pancreatography by endoscopic ultrasound in predicted severe acute biliary pancreatitis (APEC-2): a multicentre prospective study	77
Growth rates and histopathological outcomes of small (6–9 mm) colorectal polyps based on CT colonography surveillance and endoscopic removal	76
Response to McAlindon’s letter	76
Immunomodulation and entry inhibition: selgantolimod’s double punch against hepatitis B virus	76
FTO/m6A/GPNMB axis: a novel promising target for hepatocellular carcinoma (HCC) treatment?	75
Mast cells and histamine in cholangiocarcinoma: exploring overlooked avenues for enhanced patient management	73
Poking at probiotic mechanisms and microbial implications in cancer prevention and treatment	73
Empiric use of standard triple therapy inHelicobacter pylorieradication does not require readjustment in the clarithromycin resistance cut-off point	73
Patient-reported experience of colonoscopy in Italy: a multicentre prospective observational study	72
Risk of colorectal neoplasia after removal of conventional adenomas and serrated polyps: a comprehensive evaluation of risk factors and surveillance use	72
Reducing low risk of transmissible infection in duodenoscopes: at what cost to the planet?	71
GI highlights from the literature	70
Comparing the relative efficacy of therapeutics for eosinophilic oesophagitis: is counting eosinophils the right target?	69
Hidden link in gut–joint axis: gut microbes promote rheumatoid arthritis at early stage by enhancing ascorbate degradation	68
Coeliac disease: the paradox of diagnosing a food hypersensitivity disorder with autoantibodies	68
Vale Professor Marjorie M Walker	67
Genetic and transcriptomic landscape of colonic diverticulosis	66
Ferritin—a promising biomarker in MASLD	66
Pancreatic cancer surveillance and its ongoing challenges: is it time to refine our eligibility criteria?	65
Presenilins: the hidden guardians of gut health in Alzheimer’s disease	63
Direct toll-like receptor triggering in colorectal cancer-associated stromal cells elicits immunostimulatory properties leading to enhanced immune cell recruitment	61
GI highlights from the literature	61
Porcine-derived pancreatic enzyme replacement therapy: a cause of hepatitis E virus transmission?	61
Proton pump inhibitors and gastric cancer: a population-based cohort study	61
Suppressor CD4+T cells expressing HLA-G are expanded in the peripheral blood from patients with acute decompensation of cirrhosis	60
Diagnostic upper GI endoscopy: can less mean more?	60
Faecal proteomics links neutrophil degranulation with mortality in patients with alcohol-associated hepatitis	59
Liquid biopsy to identify Barrett’s oesophagus, dysplasia and oesophageal adenocarcinoma: theEMERALDmulticentre study	58
Perturbation of mRNA splicing in liver cancer: insights, opportunities and challenges	57
Faecalibacterium prausnitzii: one species with multiple potential implications in cancer research	57
Plasma extracellular vesicles contain unannotated small RNA clusters suitable as biomarkers for detecting early hepatocellular carcinoma	56
Unusual case of severe diarrhoea	56
Stool microRNA profiling— dumpster diving for a master marker?	55
Prospective, double-blind diagnostic multicentre study of confocal laser endomicroscopy for wheat sensitivity in patients with irritable bowel syndrome	55
Scoring systems for diverticular disease	55
HBcrAg values may predict virological and immunological responses to pegIFN-α in NUC-suppressed HBeAg-negative chronic hepatitis B	54
Is mailed outreach and patient navigation a perfect solution to improve HCC screening?	53
Unusual cause of abdominal pain	52
Liver injury, hypoalbuminaemia and severe SARS-CoV-2 infection	51
Key metabolomic alterations are associated with ulcerative colitis disease state and activity: a validation analysis	51
Role of patient and staff mobility in scope 3 emissions in GI endoscopy	51
Advancing with cancer immunotherapeutics: CD29+regulatory T cell antagonism	50
Endoluminal radiofrequency ablation prior to stenting for malignant biliary obstruction: really time to say goodbye?	50
Intravital imaging: dynamic insights into liver immunity in health and disease	49
eCura and W-eCura: different scores, different populations, same goal	49
Potential risk of porcine-derived pancreatic enzyme medication for the cross-species transmission of hepatitis E virus	49
Comprehensive single-cell analysis deciphered microenvironmental dynamics and immune regulator olfactomedin 4 in pathogenesis of gallbladder cancer	49
Acute severe ulcerative colitis trials: the past, the present and the future	48
EUS-guided gallbladder drainage in acute cholecystitis: long-term problems with surgical approach	47
Correction:P97 A patient information bundle outlining dietary advice in liver disease specific to the cost of living crisis improves patient care: ‘Looking after Your Liver for Less’	47
A novel unconventional T cell population enriched in Crohn’s disease	47
Correction:O36 Prevalence of repeat FIT testing in symptomatic patients attending primary care	46
Correction:Pan-ERBB kinase inhibition augments CDK4/6 inhibitor efficacy in oesophageal squamous cell carcinoma	46
Correction: Risk factors for SARS-CoV-2 infection and course of COVID-19 disease in patients with IBD in the Veterans Affair Healthcare System	46
Correction:Non-nucleatum Fusobacterium species are dominant in the Southern Chinese population with distinctive correlations to host diseases compared with F. nucleatum	45
Inhibition of YTHDF1 by salvianolic acid overcomes gluten-induced intestinal inflammation	45
Correction: PTH-27 Risk-stratified FIT for urgent colonoscopy in Lynch Syndrome: A clinical service throughout the COVID-19 pandemic	45
Impact of margin thermal ablation after endoscopic mucosal resection of large (≥20 mm) non-pedunculated colonic polyps on long-term recurrence	45
Correction:O11 Utilising peer support workers in hepatitis C screening in emergency departments: a pilot study	45
A mucus production programme promotes classical pancreatic ductal adenocarcinoma	45
Correction:Residual SARS-CoV-2 viral antigens detected in GI and hepatic tissues from five recovered patients with COVID-19	45
Where are we with gastric cancer screening in Europe in 2024?	44
Association between proton pump inhibitor use and gastric cancer: a population-based cohort study using two different types of nationwide databases in Korea	44
S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos	44
Methionine deficiency facilitates antitumour immunity by altering m6A methylation of immune checkpoint transcripts	44
GM-CSF drives myelopoiesis, recruitment and polarisation of tumour-associated macrophages in cholangiocarcinoma and systemic blockade facilitates antitumour immunity	44
It is better to light a candle than to curse the darkness: single-cell transcriptomics sheds new light on pancreas biology and disease	44
Stomach microbiota in gastric cancer development and clinical implications	43
Cancer pharmacomicrobiomics: targeting microbiota to optimise cancer therapy outcomes	43
TLR8 agonist selgantolimod regulates Kupffer cell differentiation status and impairs HBV entry into hepatocytes via an IL-6-dependent mechanism	43
Omega-3 polyunsaturated fatty acids: moving towards precision use for prevention and treatment of colorectal cancer	43
Large-scale, national, family-based epidemiological study onHelicobacter pyloriinfection in China: the time to change practice for related disease prevention	42
Absence of a pancreatic microbiome in intraductal papillary mucinous neoplasm	42
ETV5-S100A9 feed-forward loop connecting HCC and MDSCs to shape the immunosuppressive tumour microenvironment	42
Blockade of interleukin 10 potentiates antitumour immune function in human colorectal cancer liver metastases	42

E-twenty-six-specific sequence variant 5 (ETV5) facilitates hepatocellular carcinoma progression and metastasis through enhancing polymorphonuclear myeloid-derived suppressor cell (PMN-MDSC)-mediated	41
Faecal immunochemical testing (FIT) in patients with signs or symptoms of suspected colorectal cancer (CRC): a joint guideline from the Association of Coloproctology of Great Britain and Ireland (ACPG	40
Novel IL-4/HB-EGF-dependent crosstalk between eosinophils and macrophages controls liver regeneration after ischaemia and reperfusion injury	40
Tumour-associated neutrophils secrete AGR2 to promote colorectal cancer metastasis via its receptor CD98hc–xCT	40
Stressed hepatocyte sustains alcohol-associated hepatitis progression by producing leukocyte cell-derived chemotaxin 2	40
Updates to the modern diagnosis of GERD: Lyon consensus 2.0	40
Gut virome-colonisingOrthohepadnavirusgenus is associated with ulcerative colitis pathogenesis and induces intestinal inflammationin vivo	40
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism	40
Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation	40
Prevalence of steatotic liver disease, advanced fibrosis and cirrhosis among community-dwelling overweight and obese individuals in the USA	40
Neutrophil extracellular traps activate hepatic stellate cells and monocytes via NLRP3 sensing in alcohol-induced acceleration of MASH fibrosis	40
Sugar-sweetened beverage intake in adulthood and adolescence and risk of early-onset colorectal cancer among women	39
British Society of Gastroenterology guidelines for the management of hepatocellular carcinoma in adults	39
Mapping the human gut mycobiome in middle-aged and elderly adults: multiomics insights and implications for host metabolic health	39
Faecal microbiota transplantation with anti-inflammatory diet (FMT-AID) followed by anti-inflammatory diet alone is effective in inducing and maintaining remission over 1 year in mild to moderate ulce	38
Genetic variation inTERTmodifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: results from a genome-wide case-control study	38
Combining faecal haemoglobin, iron deficiency anaemia status and age can improve colorectal cancer risk prediction in patients attending primary care with bowel symptoms: a retrospective observational	38
CARD9 in neutrophils protects from colitis and controls mitochondrial metabolism and cell survival	37
Joint Asian Pacific Association of Gastroenterology (APAGE)–Asian Pacific Society of Digestive Endoscopy (APSDE) clinical practice guidelines on the use of non-invasive biomarkers for diagnosis of col	37
Ginseng polysaccharides alter the gut microbiota and kynurenine/tryptophan ratio, potentiating the antitumour effect of antiprogrammed cell death 1/programmed cell death ligand 1 (anti-PD-1/PD-L1) imm	37
Third Asia-Pacific consensus recommendations on colorectal cancer screening and postpolypectomy surveillance	37
CRIP1 fosters MDSC trafficking and resets tumour microenvironment via facilitating NF-κB/p65 nuclear translocation in pancreatic ductal adenocarcinoma	36
Targeted intervention to achieve waste reduction in gastrointestinal endoscopy	36
	36
Dietary macronutrients and the gut microbiome: a precision nutrition approach to improve cardiometabolic health	36
Opening the doors of precision medicine: novel tools to assess intestinal barrier in inflammatory bowel disease and colitis-associated neoplasia	36
Life cycle assessment of routinely used endoscopic instruments and simple intervention to reduce our environmental impact	36
Efficacy of biological therapies and small molecules in moderate to severe ulcerative colitis: systematic review and network meta-analysis	35
Global burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN	35
Autologous regulatory T-cell transfer in refractory ulcerative colitis with concomitant primary sclerosing cholangitis	35
Post-acute COVID-19 syndrome and gut dysbiosis linger beyond 1 year after SARS-CoV-2 clearance	35
Gut microbiome and health: mechanistic insights	34
Correspondence on “PICaSSO Histologic Remission Index (PHRI) in ulcerative colitis: development of a novel simplified histological score for monitoring mucosal healing and predicting clinical outcomes	34
Bidirectional brain–gut axis effects influence mood and prognosis in IBD: a systematic review and meta-analysis	34
Serum ferritin levels can predict long-term outcomes in patients with metabolic dysfunction-associated steatotic liver disease	34
Current therapies and new developments in NASH	34
Automated sizing of colorectal polyps using computer vision	34
Statins for MAFLD/MASH: another brick in the wall while waiting for final answers	33
Perplexing case of abdominal pain with eosinophilia and fasciitis	33
Effects of tenofovir disoproxil fumarate on intrahepatic viral burden and liver immune microenvironment in patients with chronic hepatitis B	33
Exploring the role of genetics, gut microbiota and blood metabolites in IBD	32
Definite benefits of GLP-1 receptor agonists: what is the risk of gastroparesis and lung aspiration?	32
Correction:YAP1 mediates gastric adenocarcinoma peritoneal metastases that are attenuated by YAP1 inhibition	32
Crohn’s-associated invariant T cells (CAITs) recognise small sulfonate molecules on CD1d	31
Unleashing the potential of exosome ncRNAs for early gastric cancer detection—a critical appraisal of machine learning approaches	31
Adenocarcinoma of the oesophagus: is it gastric cancer?	31
IQGAP3 signalling mediates intratumoral functional heterogeneity to enhance malignant growth	31
Practical approach to interpretation of 48-hour wireless pH-monitoring studies	31
ECM1: a novel matricellular protein with promising antifibrotic potential	31
Interactive enhancer hubs (iHUBs) mediate transcriptional reprogramming and adaptive resistance in pancreatic cancer	30
Integrative metabolomic characterisation identifies altered portal vein serum metabolome contributing to human hepatocellular carcinoma	30
Accurate liquid biopsy for the diagnosis of non-alcoholic steatohepatitis and liver fibrosis	30
Correction:British Society of Gastroenterology guidelines on sedation in gastrointestinal endoscopy	29
Correction:Growth differentiation factor 11 attenuates liver fibrosis via expansion of liver progenitor cells	29
Correction: UK guidelines on the management of variceal haemorrhage in cirrhotic patients	29
Correction: PTU-67 Differential expression of the potassium of voltage-gated channel subfamily members, kchn	29
Dysbiotic oral microbiota-derived kynurenine, induced by chronic restraint stress, promotes head and neck squamous cell carcinoma by enhancing CD8+T cell exhaustion	29
Correction: Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism	29
In vitromicrobiota model recapitulates and predicts individualised sensitivity to dietary emulsifier	29
Correction: Identification of c-FLIPL and c-FLIPS as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells	29
Redefining QUAIDE: paving the way for better AI in preclinical endoscopy	28
Large proximal gastric GIST tumours: downsizing by imatinib and subsequent endoresection	28
Is the green mark really recyclable?	28
Glucagon-like peptide-1 receptor agonist use is associated with a lower risk of major adverse liver-related outcomes: a meta-analysis of observational cohort studies	28
Dysbiosis exists in unaffected relatives of inflammatory bowel disease (IBD): emphasising the critical phases in the developmental trajectory of gut microbiota	27
Time for arginine methylation: PRMT5 inhibition to advance cholangiocarcinoma treatment	27
Severe multiple therapy refractory colitis in a 46-year-old man	27
Need for standardised approaches to human microbiome research using the example of colorectal neoplasia research	27
Understanding tissue injury and remodelling in eosinophilic oesophagitis: development towards personalised medicine	27
Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target	27
Sodium+/taurocholate cotransporting polypeptide as target therapy for liver fibrosis	27
Breast milk components modulate gut microbiota to increase susceptibility to atopic dermatitis in early life	27
SPHINX, a Guardian of Wisdom	27
Two waves of coeliac disease incidence in Sweden: a nationwide population-based cohort study from 1990 to 2015	27
Response to the letter to the editor	26
Parabacteroides distasonis: an emerging probiotic?	26
Guts UK 50 years old: onwards and upwards	26
Green gastroenterology adaptation, resilience and an industry perspective	26
Association between appendectomy and Parkinson’s disease from the UK Biobank	26
Connecting inflammatory bowel and neurodegenerative diseases: microRNAs as a shared therapeutic intervention	26
Integrative multiomics enhancer activity profiling identifies therapeutic vulnerabilities in cholangiocarcinoma of different etiologies	26
Endoscopic variceal ligation versus propranolol for the primary prevention of oesophageal variceal bleeding in patients with hepatocellular carcinoma: an open-label, two-centre, randomised controlled	26
Short-chain fatty acids in patients with severe acute pancreatitis: friend or foe?	25
Robust SARS-CoV-2 antibody and T cell immunity following three COVID-19 vaccine doses in inflammatory bowel disease patients receiving anti-TNF or alternative treatments	25
Impact of acute alcohol consumption on circulating microbiome in asymptomatic alcohol-related liver disease	25
Microbiota-induced S100A11-RAGE axis underlies immune evasion in right-sided colon adenomas and is a therapeutic target to boost anti-PD1 efficacy	24
Selective decontamination of the digestive tract in critically ill children: fighting fire with fire or burning down the house?	24
Real-world data for endoscopic therapy in LGD: not looking so good	24
Potential of personalised approaches in gastric cancer prevention	24
Pancreatic STAT5 activation promotes Kras G12D -induced and inflammation-induced acinar-to-ductal metaplasia and pancreatic cancer	24
Rare cause of liver lesion in a patient with ulcerative colitis	24
Strengths and limitations of AlphaMissense inCPA1missense variant classification	24
Mutational signatures define immune and Wnt-associated subtypes of ampullary carcinoma	23
When alcohol and fat meet, neutrophil traps form to promote liver injury	23
Refining definitions of Barrett’s oesophagus to improve clinical resource utilisation	23