Journal of Biological Chemistry

Papers
(The TQCC of Journal of Biological Chemistry is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Abstract 1981 Investigating the Pro-Inflammatory and Pro-Oxidant Effects of Wood Smoke in Murine Macrophages427
Abstract 2332 Effectiveness of antimicrobial peptides on the growth of select ESKAPE pathogens159
Abstract 2003 Measuring the substrate specificity of esterases for alcohol substituents using terbium luminescence156
Abstract 1357 Design of a biotinylated [Cp*Co(III)Cl2]2-Streptavidin Artificial Metalloenzyme for C-H bond activation143
Abstract 2006 Assessing Alterations in Hepatic Oxidation In MASLD/MASH via Preclinical Deuterium Metabolic MRI142
Abstract 2018 Lon Protease: The Jaws of Life119
Abstract 2214 Characterization of the metastatic TIME by subcellular spatial profiling116
Abstract 2016 Embracing Collaborations: Doing what we love and loving what we do111
Abstract 1395 Glycine-N-methyltransferase is not necessary for age-dependent Drosophila photoreceptor survival108
Abstract 2062 Oxidant-induced damage to equine erythrocytes from exposure to galloyl derivatives and from exposure to leaf extracts of plant species in the family Sapindaceae (sub-family Hippocastanoi106
Abstract 2679 Mentoring for Impact: Empowering Biochemistry Undergraduates and Building Futures105
Abstract 1708 Student Perspectives on AI in Higher Education: Insights from Biochemistry and Molecular Biology Classrooms103
Abstract 1559 Empowering Researchers with Accessible Molecular Animation Tools in Blender101
Abstract 2049 Telomerase Expression Levels Vary During Meiosis in Tetrahymena Thermophila95
Abstract 1599 The P2 Old protein provides broad anti-phage defense and is uninhibited by nucleotide94
Abstract 1869 In vivo pulse-chase in C. elegans reveals intestinal histone turnover changes upon starvation92
Abstract 2477 Design and Synthesis of Naphthoquinone Derivatives as Antibiotics through Inhibition of the Sodium-Dependent NADH:Ubiquinone Oxidoreductase (Na+-NQR) in Pathogenic Bacteria90
Abstract 1585 Identification of translocon-associated protein subunit beta (TRAPβ) as a regulator of cell cycle progression and apoptosis in human colorectal cancer cells90
Abstract 1272 Nephroprotective effect of the hydroalcoholic fraction of the medium polarity extract of Potentilla indica in rats with type 2 diabetes90
Abstract 1005 Mitotic Abnormalities in HPV+ Integrated Cervical and Intestinal Carcinomas by Histopathological Evaluation87
Abstract 1032 Turning the Oxygen and Vitamin Dials87
Abstract 1713 Nitric-oxide Independent Signaling Through Bacterial Heme-Nitric Oxide or Oxygen Binding Proteins (H-NOX) in Caulobacter crescentus83
Abstract 2235 Viral SF1B helicases as antiviral targets81
Abstract 1777 Investigating the Role of Pyruvate Dehydrogenase (PDH) Phosphorylation in Biofilm Formation in Δhnox Caulobacter crescentus79
Abstract 1247 AC01: A Natural Compound with Anti-Cancer Activity Targeting Wnt/ß-catenin Signaling Pathway79
Abstract 1515 Investigating the Role of Lipid Metabolism in Induced Pluripotent Stem Cells with High-Level Mitochondrial DNA Mutation Heteroplasmy79
Abstract 2090 The Effect of Cellular Differentiation on Adeno-Associated Viral Vector Genome Status75
Abstract 1549 Heme reduction in CcmFH, a key enzyme within the bacterial System I cytochrome c biogenesis pathway74
Abstract 1874 Exploring the Role of catp-6 at the C. elegans Neuromuscular Junction71
Abstract 2100 Carboxypeptidase O and glutamate carboxypeptidase II have redundant functions in C-terminal amino acid cleavage69
Abstract 1488 CTCF knockdown rescues the MAPK signaling pathway in Vezf1 null murine embryonic stem cells68
Abstract 2384 Active Site Residues of Coq11, an Atypical Short-Chain Dehydrogenase/Reductase, are Essential for Efficient Coenzyme Q Biosynthesis66
Abstract 1743 Nanopore sequencing of intact aminoacylated tRNAs66
Abstract 1221 The Role of FGFRL1 in Esophageal Carcinoma: Expression Patterns and Clinical Implications66
Abstract 1915 NHE9 Modulates Exosome Communication to Enhance Macrophage-Mediated Cardiomyocyte Repair under Oxidative Stress66
Abstract 1705 Characterizing the relationship between histone demethylases ELF6 and REF6 and the chromatin remodeler PKL in H3K27me3 homeostasis65
Abstract 1180 Development of Liposome-Based Therapeutics to Modulate Microglial Activation for Neurodegenerative Disease Treatment64
Abstract 1250 Understanding Heterotrophic Acetate Metabolism in Chlamydomonas reinhardtii64
Abstract 1027 Control of Nucleotide Metabolism and Cell Growth64
Identification of the N-terminal residues responsible for the differential microdomain localization of CYP1A1 and CYP1A263
Abstract 2749 Mentoring Undergraduate Students at Scientific Meetings: A Framework for Boosting Engagement and Persistence in Research63
Abstract 1892: Characterization of a 7-deazaguanine-based bacterial modification system61
Abstract 1531: Facilitating the collaborative scientific process through an interdisciplinary undergraduate protein modeling course61
Abstract 2625: Human brain sialoglycan ligand for CD33, a microglial inhibitory Siglec implicated in Alzheimer's disease61
Abstract 1292: Reactive Oxygen Species Production and Regulation in Human Cell61
Abstract 2318: Does Order Matter when Teaching Noncovalent Interactions: A Comparison of the Sequence of Explicit Instruction and Problem Solving60
Abstract 2236: Creation of Virtual Affinity Groups to Provide Support to Women Faculty in STEM Across a Consortium of Public Liberal Arts Colleges60
Abstract 1487: Role of calcium in mediating membrane tension and synaptic plasticity59
Abstract 1927: Cloning and recombinant expression of a lactobacillus ferulic acid esterase for potential use in beer production58
Abstract 2039 MDH CURES Community: A Supportive Network for Faculty to Increase Student Retention and Learning57
Abstract 2699: Unique interactions and functions of the mitochondrial small Tims in Trypanosoma brucei57
Abstract 2284: Elucidating FIBCD1 Binding Partners56
Abstract 2544: Radical SAM aminomutases catalyzing beta-amino acid biosynthesis for salt tolerance in methanogenic archaea56
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Abstract 1272 Structural basis for double-strand-break repair by a group II intron-like RT56
Abstract 2091: Living in the cold without brown adipose tissue lipolysis56
Abstract 2090: Probing Non-Canonical A•C Base Pairs in DNA using SERS55
Abstract 1497: The structural variance of amyloid peptides influences oxidative activity in the human brain55
Abstract 1500 Understanding the role of galactose and glucose on the composition of E. coli extracellular polymeric substance and biofilm growth55
Abstract 2018 The Anti-Cancer Effect of Acmella Extracts in Ovarian Cancer54
Abstract 2005 Interplay between charge distribution and DNA in shaping HP1 paralog phase separation and localization53
Abstract 1126 Generative Artificial Intelligence in Molecular Design and Virtual Screening of Novel Caspase-1 Inhibitors53
Abstract 2227 Mammalian Argonaute represses pericentromeric lncRNAs to maintain genome stability53
Abstract 2309: Using Support Vector Machine Classification to Predict NKX2-5 DNA Binding Sites52
Abstract 1401: Diptoindonesin G is a middle domain HSP90 modulator for cancer treatment52
Abstract 1518: BNIP3 protein abundance is controlled by phosphorylation51
Abstract 2015: Evaluating effect of metalloproteinases and their natural inhibitors on blood brain barrier51
Abstract 2386: DNP-NMR as a tool for probing the regulation of PKC signaling by membrane dissolved phorbol esters51
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Abstract 1294 Strategies for improving diversity, inclusion and belonging within undergraduate research laboratories50
Abstract 2274 Roles of phosphatidylinositol 3,4-bisphosphate in phagocytosis and bacterial invasion.49
Abstract 1631 The Ability of Metabolic Enzymes to Utilize Nicotinamide Adenine Dinucleotide Covalently Attached to RNA 5'-ends48
Abstract 1611 Coactivator condensation drives cell lineage specification47
Abstract 1255 Deciphering complexity of GPCR signaling in health and disease47
Abstract 2349 Modulation of ENPP1 Activity and 2'3'-cGAMP Degradation in Ovarian Cancer Cell Lines via Loadable Pre-formed Lipid Nanoparticles46
Abstract 1217 SARS-CoV-2 Main Protease Inhibitor High-Throughput Screen46
Abstract 1187 A novel activity of the RAD52 protein that is essential for the viability of BRCA-deficient breast and ovarian cancer cells46
Abstract 1265 Mutants on Mars: Directed Evolution of Halophile Enzyme Activity46
Abstract 1594 Immune-enhancing Effects of Lipid Extracted from Arctoscopus japonicus Eggs on Immune-suppressed Mice44
Abstract 2204 Subcellular Expression of Heat-Shock Protein in the Coral Holobiont44
Abstract 2389 Biophysical Characterization of Novel Modulators of PRL344
Abstract 1141 S100A12 thermodynamic stability and misfolding properties: Assessing the capacity of S100A12 to misfold into amyloid-like structures44
Abstract 2374 Structural Insights into the Activation Mechanism of Human ClpXP43
Abstract 1039 Quantifying the levels of Queuosine metabolites in the human diet43
Abstract 1591 Enhancing biochemical yield in S. cerevisiae43
Abstract 1853 Transcriptional regulation of the RAB8A GTPase by CK2 kinase in leukemia43
Abstract 1430 MALDI Spatial Imaging to Characterize the Competition for Metabolic Resources During Parasitoid Wasp Infection of Fly Larvae42
Abstract 1688 Expression, Purification, and Characterization Attempts of Glucan Phosphatase LSF142
Abstract 2060 Exploring the interplay between amino acids, lysosomes, and iron homeostasis42
Abstract 2716: The Prevalence of Rs5219 on the KCNJ11 Gene and Its Correlation to Type 2 Diabetes in the Hispanic/Latino Population in California41
Abstract 2370 RAD52-BRCA synthetic lethality: a search for the critical RAD52 activity41
Abstract 1366: Compounds enhancing poly(3-hydroxybutyrate) storage: cell membrane interfering agent 2-phenylethanol combined with nitrogen starvation triggered poly(3-hydroxybutyrate) accumulation in 41
Abstract 1187: A Quantitative Comparison of the Knockdown Efficiencies of CRISPR/Cas9 and CRISPR-Cas12 in Caenorhabditis elegans41
Abstract 2022: Regulation of Estrogen Receptor Signaling by FKBP52 in Breast Cancer Cells41
Abstract 1007 Novel Interactions of Potato Spindle Tuber Viroid RNA with Pokeweed Antiviral Protein40
Abstract 2653: Arachidin-1 Enhances the Anticancer Effects of Paclitaxel in Triple-Negative Breast Cancer Cells40
Abstract 1895 Educational Equity in a Community College Classroom - Using UR as a High Impact Practice Tool40
Abstract 1812: The Interplay of Acetylation and Ubiquitination40
Abstract 1517 Examining the effect of L-rhamnose metabolism on the transcriptome of Escherichia coli40
Abstract 1473: Modeling Binding of Beta-site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Aminoquinoline (68 K) for Possible Treatment of Alzheimer's Disease40
Abstract 1369 Harnessing plant specialized metabolism for new medicines through synthetic biology39
Abstract 1947 Exploring the Interplay of Social- Economic, and Racial Disparities Stress and Their Impact on Breast Cancer, with a Focus on Triple Negative Breast Cancer and Hormonal Imbalance-Induced39
Abstract 1708 CTBP1 Mutation Affects Neuronal Stem Cell Migration39
Abstract 1259 Biochemical Investigation and Evolutionary Comparison of the Mechanism of the Initiation of DNA Replication in Eukaryotic Cells39
Abstract 1370: How Selection Bias and Data Interpretation Contribute to Disparities in Health Outcomes and Artificial Intelligence Development39
Abstract 2006 Determining the Effects of Motif A Phosphorylation on SIRT1 Activity39
Abstract 1165: Potential “Release-on-Demand” Metallopolymer Coatings For Drug-Release, Biofabrication, and In Vitro Experimental Control39
Enriched G4 forming repeats in the human genome are associated with robust well-coordinated transcription and reduced cancer transcriptome variation38
Glycogen synthase kinase homolog Rim11 regulates lipid synthesis through the phosphorylation of Pah1 phosphatidate phosphatase in yeast38
Abstract 1365: Interplay Between Nicotine, BDNF, and a β-Adrenergic Receptor Blocker in Regulating Cisplatin Resistance in Lung Cancer Cells38
Abstract 2178: Understanding TAOK1 dysfunction in neurodevelopmental disorders using human stem cell derived models38
Artesunate enhances the efficacy of enzalutamide in advanced prostate cancer38
Combined inhibition of aurora kinases and Bcl-xL induces apoptosis through select BH3-only proteins38
A novel gain-of-function phosphorylation site modulates PTPN22 inhibition of TCR signaling38
Abstract 2374: MAP Kinase Phosphatases as Nodal Signal Regulators in Health and Disease38
Crystal structure and mechanistic studies of the PPM1D serine/threonine phosphatase catalytic domain38
Phosphorylation alters the mechanical stiffness of a model fragment of the dystrophin homologue utrophin38
Cryo-EM structure of ACE2-SIT1 in complex with tiagabine37
Natural and synthetic 2-oxoglutarate derivatives are substrates for oncogenic variants of human isocitrate dehydrogenase 1 and 237
Single-cell profiling identifies LIN28A mRNA targets in the mouse pluripotent-to-2C-like transition and somatic cell reprogramming37
An immunogenic cell injury module for the single-cell multiplexed activity metabolomics platform to identify promising anti-cancer natural products37
A tribute to Sidney Altman, one of the architects of modern RNA biology37
Structural and functional studies of legumain–mycocypin complexes revealed a competitive, exosite-regulated mode of interaction36
The conformation of tetraspanins CD53 and CD81 differentially affects their nanoscale organization and interaction with their partners36
Histone acetyltransferase KAT2A modulates neural stem cell differentiation and proliferation by inducing degradation of the transcription factor PAX636
Proximal cysteine residues in proteins promote Nε-carboxyalkylation of lysine residues by α-dicarbonyl compounds36
The histamine H3 receptor modulates dopamine D2 receptor–dependent signaling pathways and mouse behaviors36
Analysis of eIF4E-family members in fungi contributes to their classification in eukaryotes36
HRI protein kinase in cytoplasmic heme sensing and mitochondrial stress response: Relevance to hematological and mitochondrial diseases36
Purinosomes spatially co-localize with mitochondrial transporters35
Mutational and biophysical analyses reveal a TFIIIC binding region in the TFIIF-related Rpc53 subunit of RNA polymerase III35
Nonfunctional coq10 mutants maintain the ERMES complex and reveal true phenotypes associated with the loss of the coenzyme Q chaperone protein Coq1035
Endoplasmic reticulum protein BIK binds to and inhibits mitochondria-localized antiapoptotic proteins35
Differentiation-linked changes in the biosynthesis and turnover of sphingomyelins in rat male germ cells: Genes involved and effects of testosterone35
The permanently chaperone-active small heat shock protein Hsp17 from Caenorhabditis elegans exhibits topological separation of its N-terminal regions35
Two types of peptides derived from the neurotoxin GsMTx4 inhibit a mechanosensitive potassium channel by modifying the mechanogate35
Correction: AMP-activated protein kinase α1 promotes atherogenesis by increasing monocyte-to-macrophage differentiation35
Pre-rRNA facilitates the recruitment of RAD51AP1 to DNA double-strand breaks35
The Stathmin-2 membrane-targeting domain is required for axon protection and regulated degradation by DLK signaling35
A biallelic variant of the RNA exosome gene, EXOSC4, associated with neurodevelopmental defects impairs RNA exosome function and translation34
Temperature downshifts induce biofilm formation in Pseudomonas aeruginosa through the SiaABCD signal and functional module34
G protein–coupled estrogen receptor 1 ameliorates nonalcoholic steatohepatitis through targeting AMPK-dependent signaling34
Bacillus subtilis encodes three N-acetylcysteine deacetylase enzymes that can catalyze the final step in S-(2-succino)cysteine breakdown34
Methionine cycle inhibition disrupts antioxidant metabolism and reduces glioblastoma cell survival34
Correction: Characterization of a cytochrome P450 that catalyzes the O-demethylation of lignin-derived benzoates34
Anionic lipid vesicles have differential effects on the aggregation of early onset-associated α-synuclein missense mutants34
Staphylococcal Periscope proteins Aap, SasG, and Pls project noncanonical legume-like lectin adhesin domains from the bacterial surface34
The cytochrome c oxidase subunit COX6B1 is required for redox-sensitive early assembly and late stabilization of complex IV34
Long-range allostery mediates the regulation of plasminogen activator inhibitor-1 by cell adhesion factor vitronectin34
Binding of the brain G protein G⍺o to its potential effector RASA3 is promoted by Ca2+34
Protein arginine methyltransferase 5 is essential for oncogene product EWSR1-ATF1-mediated gene transcription in clear cell sarcoma33
Legius syndrome mutations in the Ras-regulator SPRED1 abolish its membrane localization and potentially cause neurodegeneration33
Cardiolipin metabolism regulates expression of muscle transcription factor MyoD1 and muscle development33
H2O2 transit through the mitochondrial intermembrane space promotes tumor cell growth in vitro and in vivo33
In vivo analysis of Drosophila chondroitin sulfate biosynthetic genes33
Cell targeting by the bicomponent leukocidin subunit HlgB drives Staphylococcus aureus pathophysiology33
The LDL receptor-related protein 1 (LRP1) facilitates ACE2-mediated endocytosis of SARS-CoV2 spike protein-containing pseudovirions33
Glial fibrillary acidic protein is pathologically modified in Alexander disease33
Multiple Mycobacterium abscessus O-acetyltransferases influence glycopeptidolipid structure and colony morphotype33
Mitotic chromatin compaction tethers extrachromosomal DNA to chromosomes and prevents their mis-segregation into micronuclei33
Negative cooperativity underlies dynamic assembly of the Par complex regulators Cdc42 and Par-333
N-glycan antennal modifications are altered in Caenorhabditis elegans lacking the HEX-4 N-acetylgalactosamine-specific hexosaminidase32
Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis32
Characterization of ribosome stalling and no-go mRNA decay stimulated by the fragile X protein, FMRP32
A genus-specific nsp12 region impacts polymerase assembly in Alphacoronavirus and Gammacoronavirus32
Ion channel chameleons: Switching ion selectivity by alternative splicing32
The E3 ubiquitin ligase RNF126 facilitates quality control of unimported mitochondrial membrane proteins32
A phase transition reduces the threshold for nicotinamide mononucleotide-based activation of SARM1, an NAD(P) hydrolase, to physiologically relevant levels32
The molecular principles underlying diverse functions of the SLC26 family of proteins32
Surface electrostatics dictate RNA-binding protein CAPRIN1 condensate concentration and hydrodynamic properties32
Protein engineering of a nanoCLAMP antibody mimetic scaffold as a platform for producing bioprocess-compatible affinity capture ligands32
The late-stage steps of Burkholderia cenocepacia protein O-linked glycan biosynthesis are conditionally essential32
Lipid biosynthesis perturbation impairs endoplasmic reticulum–associated degradation32
Targeting HNRNPA2B1 to overcome chemotherapy resistance in gastric cancer stem cells: Mechanisms and therapeutic potential31
Cryo-EM structures reveal the PP2A–B55α and Eya3 interaction that can be disrupted by a peptide inhibitor31
Argonaute 1 contributes to the transcriptional silencing of HIV-131
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N-glycosylation is a potent regulator of prion protein neurotoxicity31
Comparative analysis of the physical properties of murine and human S100A7: Insight into why zinc piracy is mediated by human but not murine S100A731
Protocatechuate hydroxylase is a novel group A flavoprotein monooxygenase with a unique substrate recognition mechanism31
Krüppel-like factor 12 regulates aging ovarian granulosa cell apoptosis by repressing SPHK1 transcription and sphingosine-1-phosphate (S1P) production31
mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome31
C9orf72-associated dipeptide protein repeats form A11-positive oligomers in amyotrophic lateral sclerosis and frontotemporal dementia31
The activity of the ribonucleotide monophosphatase UmpH is controlled by interaction with the GlnK signaling protein in Escherichia coli31
Molecular basis of IFN-γ–induced STAT3 phosphorylation stimulated by Sendai virus C protein30
Peroxynitrite detoxification by Trypanosoma cruzi heme peroxidase supports parasite survival in macrophages30
A short-chain acyl-CoA synthetase that supports branched-chain fatty acid synthesis in Staphylococcus aureus30
A higher plant FAD synthetase is fused to an inactivated FAD pyrophosphatase30
IL4I1 overexpression protects against nonalcoholic fatty liver disease in part by inhibiting the AKT/FOXO1 pathway-mediated Th17 cell differentiation30
Human UFSP1 translated from an upstream near-cognate initiation codon functions as an active UFM1-specific protease30
CLIC5A binds to and stabilizes the open and active conformation of ezrin30
Cannabinoid CB2 receptors are upregulated via bivalent histone modifications and control primary afferent input to the spinal cord in neuropathic pain30
Declining activity of serum response factor in aging aorta in relation to aneurysm progression30
Antimicrobial peptides selectively target malaria parasites by a cholesterol-dependent mechanism30
Nesprin-2 is a novel scaffold protein for telethonin and FHL-2 in the cardiomyocyte sarcomere29
Slow PPi release enhances fidelity of the SARS-CoV-2 RNA dependent RNA polymerase29
Small RNA ASpks2 Promote Mycobacterium tuberculosis Survival in Macrophages via Targeting Polyketide Synthase 229
Functionally redundant formate dehydrogenases enable formate-dependent growth in Methanococcus maripaludis29
Maternal obesity alters histone modifications mediated by the interaction between EZH2 and AMPK, impairing neural differentiation in the developing embryonic brain cortex29
Biosynthetic and genetic pathways related to sialic acid metabolism29
Approximate size and preliminary composition of the low-mass zinc pool in the cytosol of Saccharomyces cerevisiae29
Histone fold domain positioning dictates cotranslational heterodimeric assembly of paralogous TAF12/TAF12L in Candida albicans29
GPR39-mediated molecular signaling by bile acids29
A transthyretin monomer intermediate undergoes local unfolding and transient interaction with oligomers in a kinetically concerted aggregation pathway29
Transport of sphingolipids by yeast Npc2 supports phase separation of the vacuole membrane29
Structural basis of membrane machines that traffick and attach heme to cytochromes28
A tumor microenvironment-activated metal-organic framework–based nanoplatform for amplified oxidative stress–induced enhanced chemotherapy28
PLTP is a p53 target gene with roles in cancer growth suppression and ferroptosis28
The human autophagy-initiating complexes ULK1C and PI3KC3-C128
Hhatl ameliorates endoplasmic reticulum stress through autophagy by associating with LC328
Identification of nonhistone substrates of the lysine methyltransferase PRDM928
SLC52A1 is a neofunctionalized primate urate transporter enabling intestinal urate secretion28
Targeted protein posttranslational modifications by chemically induced proximity for cancer therapy28
Metabolic control of luteinizing hormone-responsive ovarian steroidogenesis28
Structural and functional characterization of the IpaD π-helix reveals critical roles in DOC interaction, T3SS apparatus maturation, and Shigella virulence28
Forces that shape the transcriptome: Linking cellular mechanosensing to mRNA splicing28
A bacterial actin with high ATPase activity regulates the polymerization of a partner MreB isoform essential for Spiroplasma swimming motility28
Structural basis of RNA polymerase II transcription on the histone H3–H4 octasome28
PKM2 inhibitor suppresses kidney fibrogenesis by disrupting YAP-TEAD-CCN2 transcriptional signaling following ischemia–reperfusion injury28
Domain-specific functions of LRIT3 in synaptic assembly and retinal signal transmission28
Novel Z-DNA binding domains in giant viruses27
Structural and functional analysis of a bile salt hydrolase from the bison microbiome27
Minor hemolysin-coregulated proteins (Hcp) form heteromeric complexes and mediate effector secretion in Bacteroidales type VI secretion systems27
Activity-dependent modulation of neuronal KV channels by retinoic acid enhances CaV channel activity27
The C-terminal domain of the antiamyloid chaperone DNAJB6 binds to amyloid-β peptide fibrils and inhibits secondary nucleation27
DNA polymerase ζ has robust reverse transcriptase activity relative to other cellular DNA polymerases27
Rare variants of DNA ligase 1 show distinct mechanisms of deficiency27
Critical roles of protein disulfide isomerases in balancing proteostasis in the nervous system27
Transportin 1 is a major nuclear import receptor of the nitric oxide synthase interacting protein27
Live cell analysis of mobility and decay kinetics of the histone variant H3.327
Exploration of O-GlcNAc transferase glycosylation sites reveals a target sequence compositional bias27
Retinal-phospholipid Schiff-base conjugates and their interaction with ABCA4, the ABC transporter associated with Stargardt disease27
Transmembrane serine protease TMPRSS2 implicated in SARS-CoV-2 infection is autoactivated intracellularly and requires N-glycosylation for regulation27
Cardioprotective effect of genetic ablation of the G-protein-coupled receptor kinase GRK2 in adult pancreatic β-cells during high-fat diet26
Conformational interdomain flexibility in a bacterial α-isopropylmalate synthase is necessary for leucine biosynthesis26
The green ESCRTs: Newly defined roles for ESCRT proteins in plants26
Transcription blocking properties and transcription-coupled repair of N2-alkylguanine adducts as a model for aldehyde-induced DNA damage26
An engineered cell line with a hRpn1-attached handle to isolate proteasomes26
Sls1 and Mtf2 mediate the assembly of the Mrh5C complex required for activation of cox1 mRNA translation26
A combination of alveolar type 2–specific p38α activation with a high-fat diet increases inflammatory markers in mouse lungs26
Direct SpoIIQ-SpoIIIAH interaction is dispensable for sporulation in Bacillus subtilis26
Lysyl hydroxylase 3–mediated post-translational modifications are required for proper biosynthesis of collagen α1α1α2(IV)26
RNA polymerase I (Pol I) lobe-binding subunit Rpa12.2 promotes RNA cleavage and proofreading26
BATF2 inhibits PD-L1 expression and regulates CD8+ T-cell infiltration in non–small cell lung cancer26
Mechanistic insights into complement pathway inhibition by CR1 domain duplication26
Spatiotemporal control of kinases and the biomolecular tools to trace activity26
Myeloid loss of scaffolding protein menin promotes liver fibrosis via H3K36me3 reprogramming26
A type II toxin–antitoxin system is responsible for the cell death at low temperature in Pseudomonas syringae Lz4W lacking RNase R26
Kinetics insight into the roles of the N- and C-lobes of calmodulin in RyR1 channel regulation26
Conversion of glutamate into proline by the leucine analog BCH enhances biphasic insulin secretion in pancreatic β-cells26
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