Journal of Cell Biology

Article	Citations
LUBAC regulates ciliogenesis by promoting CP110 removal from the mother centriole	337
A conserved role for centriolar satellites in translation of centrosomal and ciliary proteins	145
Mechanisms of genome instability from cellular folate stress	135
A function of TPL/TBL1-type corepressors is to nucleate the assembly of the preinitiation complex	123
PP6 regulation of Aurora A–TPX2 limits NDC80 phosphorylation and mitotic spindle size	99
Differential metabolism of arsenicals regulates Fps1-mediated arsenite transport	93
Tubulin isotypes optimize distinct spindle positioning mechanisms during yeast mitosis	80
The PAX3-FOXO1 fusion gene reduces cell–ECM interactions and TGFβ signaling in rhabdomyosarcoma	80
DBF4, not DRF1, is the crucial regulator of CDC7 kinase at replication forks	78
Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin	72
GxcM-Fbp17/RacC-WASP signaling regulates polarized cortex assembly in migrating cells via Arp2/3	71
Sugar-free synapses run on mitochondrial Sirtuin 3	71
RIM and MUNC13 membrane–binding domains are essential for neuropeptide secretion	71
ESCRT-I and PTPN23 mediate microautophagy of ubiquitylated tau aggregates	69
Distinct roles of two homologous kinesins in mammalian motile cilia	68
A collective strategy to promote the dissemination of single cancer cells	65
Diverse microtubule-binding repeats regulate TPX2 activities at distinct locations within the spindle	65
Microtubule-driven cell shape changes and actomyosin flow synergize to position the centrosome	65
Tld1 is a regulator of triglyceride lipolysis that demarcates a lipid droplet subpopulation	63
Lipid droplets: Open questions and conceptual advances around a unique organelle	62
Kinetochores grip microtubules with directionally asymmetric strength	62
Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage	61
Vps13-like proteins provide phosphatidylethanolamine for GPI anchor synthesis in the ER	61
Developmental pruning of sensory neurites by mechanical tearing in Drosophila	61
VPS13B is localized at the interface between Golgi cisternae and is a functional partner of FAM177A1	59

The α-Catenin mechanosensing M region is required for cell adhesion during tissue morphogenesis	59
Reticulons promote formation of ER-derived double-membrane vesicles that facilitate SARS-CoV-2 replication	59
Rac1 promotes kidney collecting duct integrity by limiting actomyosin activity	59
Crosstalk within and beyond the Polycomb repressive system	57
Astral microtubule cross-linking safeguards uniform nuclear distribution in the Drosophila syncytium	56
PD-LI promotes rear retraction during persistent cell migration by altering integrin β4 dynamics	55
TIMP-1 is a novel ligand of Amyloid Precursor Protein and triggers a proinflammatory phenotype in human monocytes	54
Liquid–liquid phase separation facilitates the biogenesis of secretory storage granules	54
ARHGEF17/TEM4 regulates the cell cycle through control of G1 progression	53
The phospholipids cardiolipin and phosphatidylethanolamine differentially regulate MDC biogenesis	51
A gene duplication of a septin reveals a developmentally regulated filament length control mechanism	51
SARS-CoV-2 specific adaptations in N protein inhibit NF-κB activation and alter pathogenesis	51
Cryo-EM reveals how the mastigoneme assembles and responds to environmental signal changes	49
Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking	49
Centriole structural integrity defects are a crucial feature of hydrolethalus syndrome	49
FGFR2 residence in primary cilia is necessary for epithelial cell signaling	48
C17orf80 binds the mitochondrial genome to promote its replication	47
PtdIns(3,4)P2, Lamellipodin, and VASP coordinate actin dynamics during phagocytosis in macrophages	46
Rab GTPases as “eat me” signals for selective autophagy	46
Organization of a cytoskeletal superstructure in the apical domain of intestinal tuft cells	46
Phollow the phosphoinositol: Actin dynamics at the B cell immune synapse	46
Bill Weis (1959–2023): Pioneering structural biologist and biochemist who revolutionized our understanding of cell adhesion and Wnt signaling	45
Mechanisms of nuclear segregation in a multinucleate multibudding yeast	43
Taperin bundles F-actin at stereocilia pivot points enabling optimal lifelong mechanosensitivity	43
Migrasomes: Biogenesis, physiological roles, and therapeutic potentials	43
Refining S-acylation: Structure, regulation, dynamics, and therapeutic implications	42
Migratory autolysosome disposal mitigates lysosome damage	42
Stu2 performs an essential kinetochore function independent of its microtubule polymerase activity	42
Newborn daughters get a fresh start through PI(3,5)P2-mediated vacuolar acidification	41
Human atlastin-3 is a constitutive ER membrane fusion catalyst	41
Allocation of resources among multiple daughter cells	41
A guide to membrane atg8ylation and autophagy with reflections on immunity	39
New editorial board members	39
Competition for calnexin binding regulates secretion and turnover of misfolded GPI-anchored proteins	39
A complex of the lipid transport ER proteins TMEM24 and C2CD2 with band 4.1 at cell–cell contacts	38
Microtubule-binding domains in Katanin p80 subunit are essential for severing activity inC. elegans	38
Induced nanoscale membrane curvature bypasses the essential endocytic function of clathrin	37
Spatially coordinated cell cycle activity and motility govern bifurcation of mammary branches	37
A biotin-HaloTag ligand enables efficient affinity capture of protein variants from live cells	37
Vav independently regulates synaptic growth and plasticity through distinct actin-based processes	37
Paxillin phase separation promotes focal adhesion assembly and integrin signaling	35
Eps15/Pan1p is a master regulator of the late stages of the endocytic pathway	34
In situ cryo-electron tomography reveals local cellular machineries for axon branch development	34
StableMARK-decorated microtubules in cells have expanded lattices	34
Genome-wide conditional degron libraries for functional genomics	33
Force tuning through regulation of clathrin-dependent integrin endocytosis	33
Repression of CENP-A assembly in metaphase requires HJURP phosphorylation and inhibition by M18BP1	33
Bidirectional regulation of calcium release–activated calcium (CRAC) channel by SARAF	33
The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling	33
Septin-mediated RhoA activation engages the exocyst complex to recruit the cilium transition zone	33

DeepContact: High-throughput quantification of membrane contact sites based on electron microscopy imaging	33
RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors	33
A fluorogenic complementation tool kit for interrogating lipid droplet–organelle interaction	32
LC3B is a cofactor for LMX1B-mediated transcription of autophagy genes in dopaminergic neurons	32
SUMOylation at the inner nuclear membrane facilitates nuclear envelope biogenesis during mitosis	32
A covalently linked probe to monitor local membrane properties surrounding plasma membrane proteins	32
Mitochondrial fission controls astrocyte morphogenesis and organization in the cortex	32
Spindle morphology changes between meiosis and mitosis driven by CK2 regulation of the Ran pathway	32
ER-localized Shr3 is a selective co-translational folding chaperone necessary for amino acid permease biogenesis	32
Plan your trip before you leave: The neutrophils’ search-and-run journey	32
Coronin 1C restricts endosomal branched actin to organize ER contact and endosome fission	31
Reticular adhesions are assembled at flat clathrin lattices and opposed by active integrin α5β1	31
Endosomal recycling defects link Huntington’s disease with McLeod syndrome	31
Interphase microtubule disassembly is a signaling cue that drives cell rounding at mitotic entry	31
Centralspindlin proteins Pavarotti and Tumbleweed along with WASH regulate nuclear envelope budding	31
The low-density lipoprotein receptor–mTORC1 axis coordinates CD8+ T cell activation	30
ATG9A facilitates the closure of mammalian autophagosomes	30
Correction: Netrins and neogenin promote myotube formation	30
Mitochondria–ER–PM contacts regulate mitochondrial division and PI(4)P distribution	30
Hyperstabilization of T cell microvilli contacts by chimeric antigen receptors	30
Efficient progranulin exit from the ER requires its interaction with prosaposin, a Surf4 cargo	30
PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins	29
Autolysosomal exocytosis of lipids protect neurons from ferroptosis	29
T cells use focal adhesions to pull themselves through confined environments	29
New insights into IRE1α activation and function in anti-tumor immunity	29
Axonal transport of autophagosomes is regulated by dynein activators JIP3/JIP4 and ARF/RAB GTPases	29
A membrane-sensing mechanism links lipid metabolism to protein degradation at the nuclear envelope	29
The role of midbody-associated mRNAs in regulating abscission	29
A Lifeact-EGFP quail for studying actin dynamics in vivo	29
Super-resolution microscopy: Insights into mitochondria–lysosome crosstalk in health and disease	28
Visualizing ER-phagy and ER architecture in vivo	28
OMA1 clears traffic jam in TOM tunnel in mammals	28
Not just protons: Chloride also activates lysosomal acidic hydrolases	28
Sara Wickström: The forces controlling our cell fate	28
Microtubule-associated proteins promote microtubule generation in the absence of γ-tubulin in human colon cancer cells	27
Synaptotagmin-1 in phase: Condensate biology reveals new insights into the synaptic calcium sensor	27
Centrosome age breaks spindle size symmetry even in cells thought to divide symmetrically	27
Periodic changes of cyclin D1 mRNA stability are regulated by PC4 modifications in the cell cycle	27
Subunit cooperation in the Get1/2 receptor promotes tail-anchored membrane protein insertion	27
Nodal modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation	27
The bioenergetics of nucleocytoplasmic transport	27
How do trypanosome IFT trains choose special tracks?	26
Extracellular vesicles adhere to cells primarily by interactions of integrins and GM1 with laminin	26
Meiotic nuclear pore complex remodeling provides key insights into nuclear basket organization	26
Mechanical control of osteoclast fusion by membrane-cortex attachment and BAR proteins	26
Kinesin-1 autoinhibition facilitates the initiation of dynein cargo transport	26
Inhibition of endolysosome fusion increases exosome secretion	26
Faa1 membrane binding drives positive feedback in autophagosome biogenesis via fatty acid activation	25
Endothelial depletion of Atg7 triggers astrocyte–microvascular disassociation at blood–brain barrier	25
Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin	25
Composition and organization of kinetochores show plasticity in apicomplexan chromosome segregation	25
A farnesyl-dependent structural role for CENP-E in expansion of the fibrous corona	25
A proteome-wide yeast degron collection for the dynamic study of protein function	25
Binucleated human hepatocytes arise through late cytokinetic regression during endomitosis M phase	24
Lactylation stabilizes TFEB to elevate autophagy and lysosomal activity	24
Fusion pore dynamics of large secretory vesicles define a distinct mechanism of exocytosis	24
Tailored assemblies of COPII proteins in secretion	24
Engineered synaptic tools reveal localized cAMP signaling in synapse assembly	24
NuMA is a mitotic adaptor protein that activates dynein and connects it to microtubule minus ends	24
CDR2 is a dynein adaptor recruited by kinectin to regulate ER sheet organization	24
Active RB causes visible changes in nuclear organization	23
Clathrin: Bender or bystander?	23
Structural characterization and inhibition of the interaction between ch-TOG and TACC3	23
An interaction between β′-COP and the ArfGAP, Glo3, maintains post-Golgi cargo recycling	23
Lena Ho: Micropeptides under the spotlight	23
Rickettsia parkeri forms extensive, stable contacts with the rough endoplasmic reticulum	23
Tension-induced suppression of allosteric conformational changes coordinates kinesin-1 stepping	23
Cell death leaves a new TRAIL	23
Making lipids very unhappy to discover how they bind to proteins	22
Splicing under stress: A matter of time and place	22
Atg39 links and deforms the outer and inner nuclear membranes in selective autophagy of the nucleus	22
The autophagy protein ATG-9 regulates lysosome function and integrity	22
Lineage tracing clarifies the cellular origin of tissue-resident macrophages in the developing heart	21
A plant-specific bridging adaptor for amphisome biogenesis	21
The p97 ATPase and its adaptor UBXD8 maintain peroxisome pools by preventing pexophagy	21
Ubiquitin ligase MARCH5 localizes to peroxisomes to regulate pexophagy	21
Karyopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage	21
Integration of cell wall synthesis and chromosome segregation during cell division in Caulobacter	21
α-Catenin force-sensitive binding and sequestration of LZTS2 leads to cytokinesis failure	21
JIP4 and RILPL1 utilize opposing motor force to dynamically regulate lysosomal tubulation	21

Tubulin isotypes contribute opposing properties to balance anaphase spindle morphogenesis	21
Prolonged depletion of profilin 1 or F-actin causes an adaptive response in microtubules	21
PI(4,5)P2 diffuses freely in the plasma membrane even within high-density effector protein complexes	20
Structural response of microtubule and actin cytoskeletons to direct intracellular load	20
Plasticity of mitotic cyclins in promoting the G2–M transition	20
p24 family Tango(1) at the endoplasmic reticulum exit site to organize cargo exit	20
Centriole growth is limited by the Cdk/Cyclin-dependent phosphorylation of Ana2/STIL	20
Cell polarity changes in cancer initiation and progression	20
Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN	20
Ubiquitinating the way to T cell metabolism	20
Directed stochasticity: Building biomolecular condensates in the right place	20
CEP97 phosphorylation by Dyrk1a is critical for centriole separation during multiciliogenesis	20
Ca2+ binding to Esyt modulates membrane contact site density in Drosophila photoreceptors	20
IRSp53 promotes postsynaptic density formation and actin filament bundling	20
Fission-independent compartmentalization of mitochondria during budding yeast cell division	20
Nuclear poly-glutamine aggregates rupture the nuclear envelope and hinder its repair	20
Correction: Stressed-out yeast do not pass GO	20
Determining how many cells to average for statistical testing of microscopy experiments	20
Murine glial protrusion transcripts predict localized Drosophila glial mRNAs involved in plasticity	19
The emerging roles of non-canonical ubiquitination in proteostasis and beyond	19
A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells	19
Bridging condensins mediate compaction of mitotic chromosomes	19
ARHGAP17 regulates the spatiotemporal activity of Cdc42 at invadopodia	19
APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size	19
Establishing spatial control over TORC1 signaling	19
NME3 binds to phosphatidic acid and mediates PLD6-induced mitochondrial tethering	19
The minus-end depolymerase KIF2A drives flux-like treadmilling of γTuRC-uncapped microtubules	19
ER as master regulator of membrane trafficking and organelle function	19
mTORC2 suppresses cell death induced by hypo-osmotic stress by promoting sphingomyelin transport	19
Long live lamins	19
LYSMD proteins promote activation of Rab32-family GTPases for lysosome-related organelle biogenesis	19
Painting lysosomes to study organelle heterogeneity	19
RFWD3 promotes ZRANB3 recruitment to regulate the remodeling of stalled replication forks	19
iASPP contributes to cell cortex rigidity, mitotic cell rounding, and spindle positioning	18
Balancing cell polarity PARts through dephosphorylation	18
Oiling the wheels of nuclear division: SUMOylation regulates the expansion of the mitotic nuclear membrane	18
Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation	18
Molding a PI(3,5)P2 biosensor	18
RAB-10 cooperates with EHBP-1 to capture vesicular carriers during post-Golgi exocytic trafficking	18
ARF3 weights the balance for prostate cancer metastasis	18
ISWI chromatin remodeling complexes recruit NSD2 and H3K36me2 in pericentromeric heterochromatin	18
VASH1–SVBP and VASH2–SVBP generate different detyrosination profiles on microtubules	18
LGI3/2–ADAM23 interactions cluster Kv1 channels in myelinated axons to regulate refractory period	18
Zn2+ decoration of microtubules arrests axonal transport and displaces tau, doublecortin, and MAP2C	18
One step 4× and 12× 3D-ExM enables robust super-resolution microscopy of nanoscale cellular structures	18
Expanded directly binds conserved regions of Fat to restrain growth via the Hippo pathway	18
Vinculin is required for interkinetic nuclear migration (INM) and cell cycle progression	18
Tweaking neural organoids to model human reactive astrocytes	18
Claudin 7 suppresses invasion and metastasis through repression of a smooth muscle actin program	18
The Ndc80-Cdt1-Ska1 complex is a central processive kinetochore–microtubule coupling unit	18
Nanoscale architect: Illuminating the key organizer of the fruit fly’s sensory world	18
SIR telomere silencing depends on nuclear envelope lipids and modulates sensitivity to a lysolipid	18
Centrosome-organized plasma membrane infoldings linked to growth of a cortical actin domain	17
JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport	17
Deep learning techniques and mathematical modeling allow 3D analysis of mitotic spindle dynamics	17
Liquid–liquid phase separation mediates the formation of herpesvirus assembly compartments	17
CLASPs stabilize the pre-catastrophe intermediate state between microtubule growth and shrinkage	17
A collagen IV fluorophore knock-in toolkit reveals trimer diversity in C. elegans basement membranes	17
Vacuolar pH regulates clathrin-mediated endocytosis through TORC1 signaling during replicative aging	17
WAVE complex forms linear arrays at negative membrane curvature to instruct lamellipodia formation	17
Unveiling the TRAPP: The role of plant TRAPPII in adaptive growth decisions	17
Ribbon boosts ribosomal protein gene expression to coordinate organ form and function	17
RTN3 and RTN4: Architects of SARS-CoV-2 replication organelles	17
AMPK regulates phagophore-to-autophagosome maturation	17
SHIP164 is a chorein motif lipid transfer protein that controls endosome–Golgi membrane traffic	17
FUT8-mediated core fucosylation stabilizes TMEM67 to promote ciliogenesis	17
Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodeling	17
Protein Kinase C promotes peroxisome biogenesis and peroxisome–endoplasmic reticulum interaction	17
An S-acylated N-terminus and a conserved loop regulate the activity of the ABHD17 deacylase	16
Acetic acid–induced stress granules function as scaffolding complexes for Hog1 activation by Pbs2	16
Senataxin deficiency disrupts proteostasis through nucleolar ncRNA-driven protein aggregation	16
Regulation of Cajal bodies: Unexpected connection to 60S ribosomes	16
A substrate-interacting region of Parkin directs ubiquitination of the mitochondrial GTPase Miro1	16
Cytoplasmic ribosomes on mitochondria alter the local membrane environment for protein import	16
The C10orf76–PI4KB axis orchestrates CERT-mediated ceramide trafficking to the distal Golgi	16
Anillin mediates unilateral furrowing during cytokinesis by limiting RhoA binding to its effectors	16
A second chance at yeast early endosomes	16
SEPTIN9 locally activates the RhoGEF ARHGEF18 to promote early stages of mitochondrial fission	16
Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes	16
Kinetochores get a grip!	16
Ubiquitin chain variability directs substrates of the Tul1 ubiquitin ligase complex to different degradation pathways	16
IFT trains overcome an NPHP module barrier at the transition zone	16
Successful 3D imaging of cleared biological samples with light sheet fluorescence microscopy	16
The atlastin paralogs: The complexity in the tails	16
Chasing the right tail: How the ER membrane complex recognizes its substrates	16
Cargo adaptors use a handhold mechanism to engage with myosin V for organelle transport	16
XAF1 promotes colorectal cancer metastasis via VCP–RNF114–JUP axis	16
Synaptotagmin-1 undergoes phase separation to regulate its calcium-sensitive oligomerization	16
The HERCulean task of recognizing, ubiquitinating, and shielding misfolded integral membrane proteins	15
The deubiquitinase USP45 inhibits autophagy through actin regulation by Coronin 1B	15
Microglial TNFα controls daily changes in synaptic GABAARs and sleep slow waves	15
BEACH domain proteins in membrane trafficking and disease	15
CYRI controls epidermal wound closure and cohesion of invasive border cell cluster in Drosophila	15
Translation of unspliced retroviral genomic RNA in the host cell is regulated in both space and time	15
Torques within and outside the human spindle balance twist at anaphase	15