Journal of Cell Biology

Article	Citations
Sugar-free synapses run on mitochondrial Sirtuin 3	426
Distinct roles of two homologous kinesins in mammalian motile cilia	159
A function of TPL/TBL1-type corepressors is to nucleate the assembly of the preinitiation complex	125
Diverse microtubule-binding repeats regulate TPX2 activities at distinct locations within the spindle	107
PI(3)P regulates mitochondrial dynamics through FGD-dependent actin organization	106
Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage	97
A conserved role for centriolar satellites in translation of centrosomal and ciliary proteins	96
Lipid droplets: Open questions and conceptual advances around a unique organelle	95
A collective strategy to promote the dissemination of single cancer cells	94
GARLH regulates neuroligin preference for excitatory versus inhibitory synapses	91
Cholesterol depletion activates trafficking-coupled sphingolipid synthesis	88
Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin	86
GxcM-Fbp17/RacC-WASP signaling regulates polarized cortex assembly in migrating cells via Arp2/3	86
Developmental pruning of sensory neurites by mechanical tearing in Drosophila	84
Kinetochores grip microtubules with directionally asymmetric strength	79
DBF4, not DRF1, is the crucial regulator of CDC7 kinase at replication forks	76
VPS13B is localized at the interface between Golgi cisternae and is a functional partner of FAM177A1	75
Homocysteine disrupts lysosomal function by V-ATPase inhibition	74
RIM and MUNC13 membrane–binding domains are essential for neuropeptide secretion	71
Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy	71
Microtubule-driven cell shape changes and actomyosin flow synergize to position the centrosome	64
Edge-vertex flow enables rapid adhesion reinforcement under tension	63
Tld1 is a regulator of triglyceride lipolysis that demarcates a lipid droplet subpopulation	60
Reticulons promote formation of ER-derived double-membrane vesicles that facilitate SARS-CoV-2 replication	59
ESCRT-I and PTPN23 mediate microautophagy of ubiquitylated tau aggregates	59

PP6 regulation of Aurora A–TPX2 limits NDC80 phosphorylation and mitotic spindle size	58
Mechanisms of genome instability from cellular folate stress	56
The α-Catenin mechanosensing M region is required for cell adhesion during tissue morphogenesis	55
The PAX3-FOXO1 fusion gene reduces cell–ECM interactions and TGFβ signaling in rhabdomyosarcoma	55
Rab GTPases as “eat me” signals for selective autophagy	54
TIMP-1 is a novel ligand of Amyloid Precursor Protein and triggers a proinflammatory phenotype in human monocytes	53
Stu2 performs an essential kinetochore function independent of its microtubule polymerase activity	53
Bill Weis (1959–2023): Pioneering structural biologist and biochemist who revolutionized our understanding of cell adhesion and Wnt signaling	53
ER-derived caveolin-coated vesicles transport newly synthesized cholesterol to the plasma membrane	50
Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking	50
The phospholipids cardiolipin and phosphatidylethanolamine differentially regulate MDC biogenesis	49
FGFR2 residence in primary cilia is necessary for epithelial cell signaling	48
Tubulin regulates stability and localization of STMN2 by binding preferentially to its soluble form	47
A gene duplication of a septin reveals a developmentally regulated filament length control mechanism	47
uPA-mediated remodeling of CCL21 gradients regulates lymphatic migration of dendritic cells	47
Separating chromosomes, one way or another	46
SARS-CoV-2 specific adaptations in N protein inhibit NF-κB activation and alter pathogenesis	46
Migratory autolysosome disposal mitigates lysosome damage	46
Taperin bundles F-actin at stereocilia pivot points enabling optimal lifelong mechanosensitivity	46
Organization of a cytoskeletal superstructure in the apical domain of intestinal tuft cells	45
PtdIns(3,4)P2, Lamellipodin, and VASP coordinate actin dynamics during phagocytosis in macrophages	44
Crosstalk within and beyond the Polycomb repressive system	43
C17orf80 binds the mitochondrial genome to promote its replication	43
ARHGEF17/TEM4 regulates the cell cycle through control of G1 progression	42
Cdc5-mediated Ulp2 phosphorylation controls the timing of polySUMOylation during the cell cycle	42
Migrasomes: Biogenesis, physiological roles, and therapeutic potentials	42
Centriole structural integrity defects are a crucial feature of hydrolethalus syndrome	41
Allocation of resources among multiple daughter cells	40
A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking	40
Refining S-acylation: Structure, regulation, dynamics, and therapeutic implications	40
Liquid–liquid phase separation facilitates the biogenesis of secretory storage granules	39
Mechanisms of nuclear segregation in a multinucleate multibudding yeast	39
Phollow the phosphoinositol: Actin dynamics at the B cell immune synapse	39
Cryo-EM reveals how the mastigoneme assembles and responds to environmental signal changes	39
Repression of CENP-A assembly in metaphase requires HJURP phosphorylation and inhibition by M18BP1	38
Human atlastin-3 is a constitutive ER membrane fusion catalyst	38
Understanding microtubule dynamics: The synergy of technology, theory, and experiment	38
Newborn daughters get a fresh start through PI(3,5)P2-mediated vacuolar acidification	38
Phosphatidylserine exposure and annexin A5 weaken the actin cortex in osteoclast fusion	38
Perinuclear non-centrosomal microtubules direct nuclei dispersion during epithelial morphogenesis	37
Eps15/Pan1p is a master regulator of the late stages of the endocytic pathway	37
Vav independently regulates synaptic growth and plasticity through distinct actin-based processes	36
Microtubule-binding domains in Katanin p80 subunit are essential for severing activity inC. elegans	36
Spatially coordinated cell cycle activity and motility govern bifurcation of mammary branches	36
B4GALT1 and Wntless collaborate to block LRP5/6 translocation from Golgi to cell surface	36
Genome-wide conditional degron libraries for functional genomics	36
Septin-mediated RhoA activation engages the exocyst complex to recruit the cilium transition zone	36
Force tuning through regulation of clathrin-dependent integrin endocytosis	35
A biotin-HaloTag ligand enables efficient affinity capture of protein variants from live cells	35
A complex of the lipid transport ER proteins TMEM24 and C2CD2 with band 4.1 at cell–cell contacts	35

Competition for calnexin binding regulates secretion and turnover of misfolded GPI-anchored proteins	34
StableMARK-decorated microtubules in cells have expanded lattices	34
Induced nanoscale membrane curvature bypasses the essential endocytic function of clathrin	34
The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling	34
A guide to membrane atg8ylation and autophagy with reflections on immunity	34
Paxillin phase separation promotes focal adhesion assembly and integrin signaling	34
DeepContact: High-throughput quantification of membrane contact sites based on electron microscopy imaging	33
Plan your trip before you leave: The neutrophils’ search-and-run journey	33
ER-localized Shr3 is a selective co-translational folding chaperone necessary for amino acid permease biogenesis	33
A covalently linked probe to monitor local membrane properties surrounding plasma membrane proteins	32
Correction: Netrins and neogenin promote myotube formation	32
Irg1l regulates neuromast size via metabolic reprogramming to promote supporting cell proliferation	32
Endosomal recycling defects link Huntington’s disease with McLeod syndrome	32
The cell biologist’s guide to detecting and modulating membrane phospholipids	32
LC3B is a cofactor for LMX1B-mediated transcription of autophagy genes in dopaminergic neurons	32
Spindle morphology changes between meiosis and mitosis driven by CK2 regulation of the Ran pathway	32
Mitochondria–ER–PM contacts regulate mitochondrial division and PI(4)P distribution	31
The role of midbody-associated mRNAs in regulating abscission	31
Reticular adhesions are assembled at flat clathrin lattices and opposed by active integrin α5β1	30
Axonal transport of autophagosomes is regulated by dynein activators JIP3/JIP4 and ARF/RAB GTPases	30
The cytoskeleton contributes to abnormal genome–lamina interactions in LMNA -deficient cardiomyocytes	30
Autolysosomal exocytosis of lipids protect neurons from ferroptosis	30
SUMOylation at the inner nuclear membrane facilitates nuclear envelope biogenesis during mitosis	30
A fluorogenic complementation tool kit for interrogating lipid droplet–organelle interaction	29
Coronin 1C restricts endosomal branched actin to organize ER contact and endosome fission	29
Hyperstabilization of T cell microvilli contacts by chimeric antigen receptors	29
RCC1 depletion drives protein transport defects and rupture in micronuclei	29
ATG9A facilitates the closure of mammalian autophagosomes	29
RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors	28
Mitochondrial fission controls astrocyte morphogenesis and organization in the cortex	28
Centralspindlin proteins Pavarotti and Tumbleweed along with WASH regulate nuclear envelope budding	28
A Lifeact-EGFP quail for studying actin dynamics in vivo	28
The low-density lipoprotein receptor–mTORC1 axis coordinates CD8+ T cell activation	28
A membrane-sensing mechanism links lipid metabolism to protein degradation at the nuclear envelope	28
Sara Wickström: The forces controlling our cell fate	27
Plasma membrane-to-lysosome FGR signaling regulates endocytosis-associated lysosome homeostasis	27
The bioenergetics of nucleocytoplasmic transport	27
A proteome-wide yeast degron collection for the dynamic study of protein function	27
T cells use focal adhesions to pull themselves through confined environments	27
OMA1 clears traffic jam in TOM tunnel in mammals	27
How do trypanosome IFT trains choose special tracks?	26
Not just protons: Chloride also activates lysosomal acidic hydrolases	26
Visualizing ER-phagy and ER architecture in vivo	26
Centrosome age breaks spindle size symmetry even in cells thought to divide symmetrically	26
New insights into IRE1α activation and function in anti-tumor immunity	26
Extracellular vesicles adhere to cells primarily by interactions of integrins and GM1 with laminin	26
Nodal modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation	26
Synaptotagmin-1 in phase: Condensate biology reveals new insights into the synaptic calcium sensor	26
Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin	26
Fusion pore dynamics of large secretory vesicles define a distinct mechanism of exocytosis	26
Polyploidy reprograms epithelial cells for motility and phagocytosis via stress signaling	25
Meiotic nuclear pore complex remodeling provides key insights into nuclear basket organization	25
Endothelial depletion of Atg7 triggers astrocyte–microvascular disassociation at blood–brain barrier	25
A farnesyl-dependent structural role for CENP-E in expansion of the fibrous corona	25
Inhibition of endolysosome fusion increases exosome secretion	25
Mechanical control of osteoclast fusion by membrane-cortex attachment and BAR proteins	25
Composition and organization of kinetochores show plasticity in apicomplexan chromosome segregation	25
Faa1 membrane binding drives positive feedback in autophagosome biogenesis via fatty acid activation	25
Kinesin-1 autoinhibition facilitates the initiation of dynein cargo transport	25
Lipid packing and local geometry influence septin curvature sensing	25
A plant-specific bridging adaptor for amphisome biogenesis	24
PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins	24
Super-resolution microscopy: Insights into mitochondria–lysosome crosstalk in health and disease	24
Lactylation stabilizes TFEB to elevate autophagy and lysosomal activity	24
Periodic changes of cyclin D1 mRNA stability are regulated by PC4 modifications in the cell cycle	24
Making lipids very unhappy to discover how they bind to proteins	23
Splicing under stress: A matter of time and place	23
Prolonged depletion of profilin 1 or F-actin causes an adaptive response in microtubules	23
α-Catenin force-sensitive binding and sequestration of LZTS2 leads to cytokinesis failure	23
JIP4 and RILPL1 utilize opposing motor force to dynamically regulate lysosomal tubulation	23
Mechanometabolism of cell adhesion: Vinculin regulates bioenergetics via RhoA-ROCK	23
Binucleated human hepatocytes arise through late cytokinetic regression during endomitosis M phase	23
p62 sorts Lupus La and selected microRNAs into breast cancer-derived exosomes	23
The p97 ATPase and its adaptor UBXD8 maintain peroxisome pools by preventing pexophagy	23
Actin arginylation alters myosin engagement and F-actin patterning despite structural conservation	23
Phosphoproteomic identification of Mos–MAPK targets in meiotic cell cycle and asymmetric oocyte divisions	23
Tension-induced suppression of allosteric conformational changes coordinates kinesin-1 stepping	22
Clathrin: Bender or bystander?	22
Tubulin isotypes contribute opposing properties to balance anaphase spindle morphogenesis	22
NuMA is a mitotic adaptor protein that activates dynein and connects it to microtubule minus ends	22

The autophagy protein ATG-9 regulates lysosome function and integrity	22
Integration of cell wall synthesis and chromosome segregation during cell division in Caulobacter	22
Ist2 is a phospholipid scramblase that links lipid transport at the ER to organelle homeostasis	22
CDR2 is a dynein adaptor recruited by kinectin to regulate ER sheet organization	22
Cell polarity changes in cancer initiation and progression	21
Scrib organizes cortical actomyosin clusters to maintain adherens junctions and angiogenic sprouting	21
Ca2+ binding to Esyt modulates membrane contact site density in Drosophila photoreceptors	21
p24 family Tango(1) at the endoplasmic reticulum exit site to organize cargo exit	21
Directed stochasticity: Building biomolecular condensates in the right place	21
An interaction between β′-COP and the ArfGAP, Glo3, maintains post-Golgi cargo recycling	21
Structural characterization and inhibition of the interaction between ch-TOG and TACC3	21
An inducible multiciliated cell line resolves proteome dynamics and identifies CDK7 as a conserved regulator	21
PEX14 acts as a molecular link between optineurin and the autophagic machinery to induce pexophagy	21
Murine glial protrusion transcripts predict localized Drosophila glial mRNAs involved in plasticity	21
Rickettsia parkeri forms extensive, stable contacts with the rough endoplasmic reticulum	21
Tailored assemblies of COPII proteins in secretion	21
IRSp53 promotes postsynaptic density formation and actin filament bundling	21
Ubiquitinating the way to T cell metabolism	21
Long live lamins	21
ARHGAP17 regulates the spatiotemporal activity of Cdc42 at invadopodia	20
Centriole growth is limited by the Cdk/Cyclin-dependent phosphorylation of Ana2/STIL	20
Inwardly rectifying potassium channels promote directional sensing during neutrophil chemotaxis	20
RFWD3 promotes ZRANB3 recruitment to regulate the remodeling of stalled replication forks	20
Centrosome-organized plasma membrane infoldings linked to growth of a cortical actin domain	20
ER as master regulator of membrane trafficking and organelle function	20
Nuclear poly-glutamine aggregates rupture the nuclear envelope and hinder its repair	20
Bridging condensins mediate compaction of mitotic chromosomes	20
Structural response of microtubule and actin cytoskeletons to direct intracellular load	20
Pexophagy meets physiology	20
LYSMD proteins promote activation of Rab32-family GTPases for lysosome-related organelle biogenesis	20
The emerging roles of non-canonical ubiquitination in proteostasis and beyond	20
APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size	20
Determining how many cells to average for statistical testing of microscopy experiments	20
Plasticity of mitotic cyclins in promoting the G2–M transition	20
Fission-independent compartmentalization of mitochondria during budding yeast cell division	20
PI(4,5)P2 diffuses freely in the plasma membrane even within high-density effector protein complexes	20
Painting lysosomes to study organelle heterogeneity	20
The minus-end depolymerase KIF2A drives flux-like treadmilling of γTuRC-uncapped microtubules	20
A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells	20
RAB-10 cooperates with EHBP-1 to capture vesicular carriers during post-Golgi exocytic trafficking	20
Tepsin and AP4 mediate transport from the trans-Golgi to the plant-like vacuole in toxoplasma	20
NME3 binds to phosphatidic acid and mediates PLD6-induced mitochondrial tethering	20
ISWI chromatin remodeling complexes recruit NSD2 and H3K36me2 in pericentromeric heterochromatin	19
ARF3 weights the balance for prostate cancer metastasis	19
Molding a PI(3,5)P2 biosensor	19
Balancing cell polarity PARts through dephosphorylation	19
One step 4× and 12× 3D-ExM enables robust super-resolution microscopy of nanoscale cellular structures	19
Oiling the wheels of nuclear division: SUMOylation regulates the expansion of the mitotic nuclear membrane	19
Landscape expansion microscopy reveals interactions between membrane and phase-separated organelles	19
SHIP164 is a chorein motif lipid transfer protein that controls endosome–Golgi membrane traffic	19
Deep learning techniques and mathematical modeling allow 3D analysis of mitotic spindle dynamics	19
AMPK regulates phagophore-to-autophagosome maturation	19
JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport	19
LGI3/2–ADAM23 interactions cluster Kv1 channels in myelinated axons to regulate refractory period	19
Claudin 7 suppresses invasion and metastasis through repression of a smooth muscle actin program	19
VASH1–SVBP and VASH2–SVBP generate different detyrosination profiles on microtubules	19
Protein Kinase C promotes peroxisome biogenesis and peroxisome–endoplasmic reticulum interaction	19
Nanoscale architect: Illuminating the key organizer of the fruit fly’s sensory world	19
Zn2+ decoration of microtubules arrests axonal transport and displaces tau, doublecortin, and MAP2C	19
FUT8-mediated core fucosylation stabilizes TMEM67 to promote ciliogenesis	19
Expanded directly binds conserved regions of Fat to restrain growth via the Hippo pathway	18
A collagen IV fluorophore knock-in toolkit reveals trimer diversity in C. elegans basement membranes	18
Synaptotagmin-1 undergoes phase separation to regulate its calcium-sensitive oligomerization	18
Regulation of Cajal bodies: Unexpected connection to 60S ribosomes	18
RTN3 and RTN4: Architects of SARS-CoV-2 replication organelles	18
Liquid–liquid phase separation mediates the formation of herpesvirus assembly compartments	18
CLASPs stabilize the pre-catastrophe intermediate state between microtubule growth and shrinkage	18
Vacuolar pH regulates clathrin-mediated endocytosis through TORC1 signaling during replicative aging	18
The Ndc80-Cdt1-Ska1 complex is a central processive kinetochore–microtubule coupling unit	18
A second chance at yeast early endosomes	18
High-content phenotyping reveals Golgi dynamics and their role in cell cycle regulation	18
WAVE complex forms linear arrays at negative membrane curvature to instruct lamellipodia formation	18
SIR telomere silencing depends on nuclear envelope lipids and modulates sensitivity to a lysolipid	18
Vinculin is required for interkinetic nuclear migration (INM) and cell cycle progression	18
Ubiquitin chain variability directs substrates of the Tul1 ubiquitin ligase complex to different degradation pathways	18
Kinetochores get a grip!	18
Unveiling the TRAPP: The role of plant TRAPPII in adaptive growth decisions	18
Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation	18
α-Catenin links integrin adhesions to F-actin to regulate ECM mechanosensing and rigidity dependence	17
XAF1 promotes colorectal cancer metastasis via VCP–RNF114–JUP axis	17
A versatile cortical pattern-forming circuit based on Rho, F-actin, Ect2, and RGA-3/4	17
Palmitoylation of Tspan4 is essential for migrasome formation	17
Chasing the right tail: How the ER membrane complex recognizes its substrates	17
Actomyosin contractility and a threshold of cadherin cell adhesion are required during tissue fusion	17
Successful 3D imaging of cleared biological samples with light sheet fluorescence microscopy	17
Small lipid droplets are rigid enough to indent a nucleus, dilute the lamina, and cause rupture	17
A substrate-interacting region of Parkin directs ubiquitination of the mitochondrial GTPase Miro1	17
SEPTIN9 locally activates the RhoGEF ARHGEF18 to promote early stages of mitochondrial fission	17
The atlastin paralogs: The complexity in the tails	17
Correction: Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis	17
Cargo adaptors use a handhold mechanism to engage with myosin V for organelle transport	17
Postsynaptic BMP signaling regulates myonuclear properties in Drosophila larval muscles	17
The dynamics of centromere assembly and disassembly during quiescence	17
ER export via SURF4 uses diverse mechanisms of both client and coat engagement	17
Senataxin deficiency disrupts proteostasis through nucleolar ncRNA-driven protein aggregation	17