Journal of Cell Science

Article	Citations
Spatiotemporal regulation of organelle transport by spindle position checkpoint kinase Kin4	115
First person – Alice Dupont Juhl	109
Interview with Journal of Cell Science Editor Rob Parton	106
First person – Olivera Mitevska	91
Altered cohesin dynamics and H3K9 modifications contribute to mitotic defects in thecbf11Δlipid metabolism mutant	84
First person – François Tyckaert	83
First person – M. H. D. Fouad Zakaria	66
First person – Francisca Vitorino	65
First person – Neža Vadnjal	64
Interview with FocalPlane Scientific Advisory Board member Jennifer Waters	60
First person – Celia Segui-Perez	59
The worst	58
The system III – the workplace	58
First person – Abhishek Shinde	57
Let's review I	56
Three-dimensional beating pattern of the ciliary tip in the live ciliate Tetrahymena	51
First person – Aaron Fountain and Mélanie Mansat	50
Approaches to reduce succinate accumulation by restoration of succinate dehydrogenase activity in cultured adrenal cells	47
Functional residuomics – analyzing how missense mutations impact cellular systems	47
PI31 is a positive regulator of 20S immunoproteasome assembly	43
First person – Kamaldeep Singh	42
Evolutionary cell biology comes of age	41
The role of mitochondrial mRNA translation in cellular communication	40
Expression of Concern: RyR1 and RyR3 isoforms provide distinct intracellular Ca2+ signals in HEK 293 cells	40
Reprogramming macrophages with R848-loaded artificial protocells to modulate skin and skeletal wound healing	39

SUN4 is a spermatid type II inner nuclear membrane protein that forms heteromeric assemblies with SUN3 and interacts with lamin B3	38
Live-imaging studies reveal how microclots and the associated inflammatory response enhance cancer cell extravasation	38
Confinement plus myosin-II suppression maximizes heritable loss of chromosomes, as revealed by live-cell ChReporters	38
Nucleophagy contributes to genome stability through degradation of type II topoisomerases A and B and nucleolar components	37
Cell cycle-dependent palmitoylation of protocadherin 7 by ZDHHC5 promotes successful cytokinesis	37
Cellular effects of NAT-mediated histone N-terminal acetylation	36
Microtubules under mechanical pressure can breach dense actin networks	36
The AHR target gene scinderin activates the WNT pathway by facilitating the nuclear translocation of β-catenin	36
ARF6 plays a general role in targeting palmitoylated proteins from the Golgi to the plasma membrane	36
ER–mitochondria encounter structure connections determine drug sensitivity and virulence of Cryptococcus neoformans	35
A ULK1–MTFR1L feedback loop links mitochondrial fission, mitophagy and apoptosis	35
Metformin inactivates the cGAS-STING pathway through autophagy and suppresses senescence in nucleus pulposus cells	35
Glucocorticoids enhance chemotherapy-driven stress granule assembly and impair granule dynamics, leading to cell death	34
α- and β-tubulin C-terminal tails with distinct modifications are crucial for ciliary motility and assembly	33
Polo-like kinase 1 regulates immune synapse assembly and cytotoxic T cell function by driving microtubule dynamics	32
The insect perspective on Z-disc structure and biology	32
Culture substrate stiffness impacts human myoblast contractility-dependent proliferation and nuclear envelope wrinkling	32
Augmin complex activity finetunes dendrite morphology through non-centrosomal microtubule nucleation in vivo	31
Histone deacetylase 7 mediates lipopolysaccharide-inducible mitochondrial fission in macrophages	31
Preferential recruitment and stabilization of Myosin II at compartment boundaries in Drosophila	31
The dual Ras-association domains of Drosophila Canoe have differential roles in linking cell junctions to the cytoskeleton during morphogenesis	31
UMAD1 contributes to ESCRT-III dynamic subunit turnover during cytokinetic abscission	31
Beyond cysts – organization of epithelial networks in the murine thymus	31
First person – Chandramouli Mukherjee	30
A supracellular actin network transmits forces over long distances at the apical surface of squamous carcinoma cells	30
Cell volume regulates terminal differentiation of cultured human epidermal keratinocytes	30
Rerouting trafficking circuits through posttranslational SNARE modifications	29
TC10 on endosomes regulates the local balance between microtubule stability and dynamics through the PAK2-JNK pathway and promotes axon outgrowth	29
First person – Rebeka Tomasin	29
LCN2 promotes focal adhesion formation and invasion by stimulating c-Src activation	29
Nuclear speckles – a driving force in gene expression	29
Interview with Associate Editor Pedro Carvalho	28
First person – Kenrick Waite	28
First person – Franziska Lehne	28
First person – Aimee Uyehara	27
The scaffold protein CasL restrains membrane blebbing and promotes T cell migration	27
First person – Ana Popović	27
Mitochondrial respiration promotes Cdc37-dependent stability of the Cdk1 homolog Cdc28	27
Interview with Florence Niedergang – President of the French Society for Cell Biology	27
First person – Pablo Sánchez and Franziska Kriegenburg	27
First person – Aranya Pal and Prabin Bawali	26
Redefining colocalization analysis with a novel phasor mixing coefficient	26
30 years of nanobodies – an ongoing success story of small binders in biological research	26
Impaired biogenesis of renin granules in juxtaglomerular cells of Vps33a (D251E) mutant mice	26
First person – Hatwan Nadir	26
EPLIN-β is a novel substrate of ornithine decarboxylase antizyme 1 and mediates cellular migration	26
Dynamics of intracellular cGMP during chemotaxis in Dictyostelium cells	26
Evolving circuitries in plant signaling cascades	26
Biophysical and biochemical studies support PHD inhibitor development as a TPI deficiency therapy	25
Schwann cells are axo-protective after injury irrespective of myelination status in mouse Schwann cell–neuron cocultures	25

CYRI-B loss promotes enlarged mature focal adhesions and restricts microtubule and ERC1 access to the cell leading edge	25
A WDR47 homolog facilitates ciliogenesis by modulating intraflagellar transport	25
Incorporation of 53BP1 into phase-separated bodies in cancer cells during aberrant mitosis	25
Trophoblast organoids with physiological polarity model placental structure and function	24
Meeting report – Desmosome dysfunction and disease: Alpine desmosome disease meeting	23
Rac1 and Rac3 GTPases and TPC2 are required for axonal outgrowth and migration of cortical interneurons	23
Functions of neuronal Synaptobrevin in the post-Golgi transport of Rhodopsin in Drosophila photoreceptors	22
STAT3 signaling induced by IL-6 family cytokines modulates angiogenesis	22
Alternatively spliced STIM2.3 is an evolutionarily late store-operated Ca2+ entry regulator expressed in brain	22
Affimers and nanobodies as molecular probes and their applications in imaging	22
MitoRUSH as a tool to study the efficiency of mitochondrial import in complex I-deficient cells	22
Myosin-X recruits lamellipodin to filopodia tips	22
First person – Harini Iyer	21
Cristae shaping and dynamics in mitochondrial function	21
First person – Alex van Vliet	21
New insights into FAK structure and function in focal adhesions	21
First person – Chandra Ramakrishnan	21
First person – Rinka Hata	21
Say hello, wave goodbye	20
First person – Jiwon Lee	20
Emerging roles of p300/CBP in autophagy and autophagy-related human disorders	20
First person – Daniel Lagunas-Gomez	20
An evolutionary perspective on the relationship between kinetochore size and CENP-E dependence for chromosome alignment	20
First person – Marvin Cortez and Cullen Young	20
Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at primary cilia and regulates ciliary length and signaling	20
Qui(e)t	20
First person – Tadayuki Komori	20
Urinary renal epithelial cells can be used for NPHP1 phenotyping and a personalized therapeutic strategy	20
Cell scientist to watch – Angelika Harbauer	20
Dynamic mechanisms for membrane skeleton transitions	19
First person – Xiaofei Li	19
Necroptosis at a glance	19
A conserved domain of Cfap298 governs left–right symmetry breaking in vertebrates	19
Emerging roles of lipid transfer protein dimerization	19
AMPK promotes Arf6 activation in a kinase-independent manner upon glucose starvation	19
ISG20L1 acts as a co-activator of DAPK1 in the activation of the p53-dependent cell death pathway	19
Phosphorylation of the Aly3 C-terminus impedes aberrant endocytosis of Schizosaccharomyces pombe hexose transporter Ght5	19
ARL13B-Cerulean rescues Arl13b -null mouse from embryonic lethality and reveals a role for ARL13B in spermatogenesis	19
A novel homeostatic mechanism tunes PI(4,5)P2-dependent signaling at the plasma membrane	18
Complexity and self-organization in the evolution of cell polarization	18
Membrane tethers at a glance	18
Role of Pex31 in metabolic adaptation of the nucleus–vacuole junction	18
Toxoplasma gondii scavenges mammalian host organelles through the usurpation of host ESCRT-III and Vps4A	18
The MYO1F interactome reveals ASAP1, CD2AP and SH3KBP1 as novel adaptor proteins in podosomes and phagosomes	18
CTCF maintains centromere function and mitotic fidelity	18
Distinct nuclear and cytoplasmic assemblies and interactomes of the mammalian CTLH E3 ligase complex	18
Pyruvate plus uridine augments mitochondrial respiration and prevents cardiac hypertrophy in zebrafish and H9c2 cells	18
DNA double-strand break response at a glance	18
PIKFYVE inhibition induces endosome- and lysosome-derived vacuole enlargement via ammonium accumulation	18
Epithelial cell extrusion at a glance	18
Disordered hinge regions of the AP-3 adaptor complex promote vesicle budding from the late Golgi in yeast	18
First person – Harini Krishnan	17
Interview with the 2025 BSCB Women in Cell Biology Early Career Medal Winner Helen Weavers	17
Are we having fun yet?	17
First person – Inga Mohr	17
First person – Joe Tyler	17
Renal tissue-resident macrophages promote cystogenesis in early polycystic kidney disease	17
SART3 associates with a post-splicing complex	17
First person – Vartika Sharma	17
Filopodial protrusion driven by density-dependent Ena–TOCA-1 interactions	17
Interview with Jennifer Lippincott-Schwartz	17
Visualizing Drosophila centrioles by expansion microscopy	17
First person – Priyanka Verma	17
Correction: An evolutionarily distinct chaperone promotes 20S proteasome α-ring assembly in plants	17
AMG232 inhibits angiogenesis in glioma through the p53–RBM4–VEGFR2 pathway	17
First person – Emily McParland and Noah Gurley	17
Correction: Approaches to reduce succinate accumulation by restoration of succinate dehydrogenase activity in cultured adrenal cells	17
The Dilute domain in Canoe is not essential for linking cell junctions to the cytoskeleton but supports morphogenesis robustness	16
α-Ketoglutarate dehydrogenase complex activity modulates glutamate excitotoxicity via metabotropic regulation of NMDA receptors in primary cultures	16
Polarity reversal of stable microtubules during neuronal development	16
The SARS-CoV-2 protein NSP2 enhances microRNA-mediated translational repression	16
Substrate adhesion determines migration during mesenchymal cell condensation in chondrogenesis	16
Evidence of 14-3-3 proteins contributing to kinetochore integrity and chromosome congression during mitosis	16
Src- and Abl-family kinases activate spleen tyrosine kinase to maximize phagocytosis and Leishmania infection	16
The molecular basis of tricalbin-mediated membrane contact site organization in cells	16
cellPLATO – an unsupervised method for identifying cell behaviour in heterogeneous cell trajectory data	16
Structured RhoGEF recruitment drives myosin II organization on large exocytic vesicles	16
Radial spoke protein 9 is necessary for axoneme assembly in Plasmodium but not in trypanosomatid parasites	16
Ankyrin-B is required for the establishment and maintenance of lens cytoarchitecture, mechanics and clarity	16
Single-chromosome dynamics reveals locus-dependent dynamics and chromosome territory orientation	16

Actin assembly requirements of the formin Fus1 to build the fusion focus	16
Complementary volume electron microscopy-based approaches reveal ultrastructural changes in germline intercellular bridges	15
The LECA had a conventional kinetochore and the kinetoplastid kinetochore is a derived feature – a critical evaluation of Akiyoshi, 2025	15
First person – Guan Chen	15
First person – Caroline König	15
filoVision – using deep learning and tip markers to automate filopodia analysis	15
Quantitative proteomics reveals insights into the assembly of IFT trains and ciliary assembly	15
First person – Marc Severin	15
The small ARF-like 2 GTPase TITAN5 is linked with the dynamic regulation of IRON-REGULATED TRANSPORTER 1	15
Correction: Defining the dynamin-based ring organizing center on the peroxisome-dividing machinery isolated from Cyanidioschyzon merolae	15
First person – Julia Romano	15
Nuclear F-actin and Lamin A antagonistically modulate nuclear shape	15
First person – Sarah Barger	15
Expression of Concern: Caspase-dependent initiation of apoptosis and necrosis by the Fas receptor in lymphoid cells: onset of necrosis is associated with delayed ceramide increase	15
The worst II – eight days a week	15
First person – Clara Mutschler	15
First person – Mitchell Leih	14
First person – Mohima Mukherjee	14
First person – Sudeshna Nag	14
SBIS, a new orange fluorescent vital probe for the 4D imaging of brown algal cells	14
SGIP1 binding to the α-helical H9 domain of cannabinoid receptor 1 promotes axonal surface expression	14
Artificial tethering of constitutive centromere-associated network proteins induces CENP-A deposition without Knl2 in DT40 cells	14
The system II – getting to bed	14
First person – Nima Taefehshokr	14
The local detergent model of SNARE-mediated membrane fusion	14
The endoplasmic reticulum protein FAM134B acts as a regulator of mitochondrial morphology	14
KRAP regulates mitochondrial Ca2+ uptake by licensing IP3 receptor activity and stabilizing ER–mitochondrial junctions	14
Methotrexate alleviates chronic inflammation in a Drosophila model	14
Coilin and SUMOylation influence PARP1 dynamics and the DNA damage response	14
First person – Anthony Dornan	14
First person – Laura Quirion	14
N-acetylation of secreted proteins in Apicomplexa is widespread and is independent of the ER acetyl-CoA transporter AT1	14
A WNT4- and DKK3-driven canonical to noncanonical Wnt signaling switch controls multiciliogenesis	14
Human sperm rotate with a conserved direction during free swimming in four dimensions	14
Arsenic binds to nuclear transport factors and disrupts nucleocytoplasmic transport	14
Shock drives a STAT3 and JunB-mediated coordinated transcriptional and DNA methylation response in the endothelium	14
The UbiB family member Cqd1 forms a novel membrane contact site in mitochondria	13
Nuclear segmentation facilitates neutrophil migration	13
Go with the flow – bulk transport by molecular motors	13
Quality control of un-imported mitochondrial proteins at a glance	13
Vimentin intermediate filaments provide structural stability to the mammalian Golgi complex	13
Interplay between nuclear survivin and the PRC2 complex and its impact on H3K27me3-directed transcriptional repression	13
First person – Agostina Di Pizio	13
Cell scientist to watch – Tom MacVicar	13
StARD9 is a novel lysosomal kinesin required for membrane tubulation, cholesterol transport and Purkinje cell survival	13
Molecular insights into Profilin1-dependent regulation of cellular phosphatidylinositol-(4,5)-bisphosphate	13
ALKBH5 regulates somatic cell reprogramming in a phase-specific manner	13
First person – Yutaka Ogawa	13
Arabidopsis KASH domains are differentially required for distinct LINC complex roles in stomata, roots and pollen	13
The lever model of synaptotagmin-1 function	13
Coming into focus	13
First person – James Glover	13
First person – Poulomi Das	13
First person – Maria Sharkova	13
B cell receptor-induced protein dynamics and the emerging role of SUMOylation revealed by proximity proteomics	13
Cell scientist to watch – Charlotte Aumeier	13
First person – Sean Gombart	13
Believing is seeing – the deceptive influence of bias in quantitative microscopy	13
Cell scientist to watch – Keren Hilgendorf	13
Endosomal vesicle fusion machinery is involved with the contractile vacuole in Dictyostelium discoideum	13
Skeletal ciliopathy variants of the dynein-2 DYNC2LI1 subunit impair osteogenic differentiation of mesenchymal stem cells	13
Spatial regulation of mitochondrial membrane potential by α5β1 integrin engagement in collective cell migration	13
First person – Agnieszka Pierzynska-Mach	13
First person – Ezgi Odabasi	13
Cell Scientist to Watch – Maria Ioannou	13
Localization of the tubby domain, a PI(4,5)P2 biosensor, to E-Syt3-rich endoplasmic reticulum–plasma membrane junctions	12
A genome-wide genetic screen identifies CYRI-B as a negative regulator of CEACAM3-mediated phagocytosis	12
TBC1D15 functions as an Arl4D GAP and promotes the mitochondrial translocation of Arl4D for organelle homeostasis	12
Atypical MAP kinases – new insights and directions from amoeba	12
Perspectives in collective cell migration – moving forward	12
Beat II and Side IV keep migrating longitudinal visceral muscle precursor cells on their substratum in Drosophila	12
Salinomycin disturbs Golgi function and specifically affects cells in epithelial-to-mesenchymal transition	12
Lamellipodia-like actin networks in cells lacking WAVE regulatory complex	12
Stem cell expression of CXCR4 regulates tissue composition in the vomeronasal organ	12
Centrosome amplification promotes cell invasion via cell–cell contact disruption and Rap-1 activation	12
The E2 ubiquitin-conjugating enzymes UBE2D1 and UBE2D2 regulate VEGFR2 dynamics and endothelial function	12
ConFERMing the role of talin in integrin activation and mechanosignaling	12
Time-resolved proximity biotinylation implicates a porin protein in export of transmembrane malaria parasite effectors	12
Signaling and actin waves at a glance	12
DRP1 mutations associated with EMPF1 encephalopathy alter mitochondrial membrane potential and metabolic programs	12
Segregation of nascent GPCRs in the ER-to-Golgi transport by CCHCR1 via direct interaction	12
Vps9d1 regulates tubular endosome formation through specific activation of Rab22A	12
Myosin II tension sensors visualize force generation within the actin cytoskeleton in living cells	12
Cellular and molecular functions of SETD2 in the central nervous system	12
First person – Presley Roberts	12
Progerin cross-linking stiffens the nucleus and impairs mechanosensation in Hutchinson-Gilford progeria syndrome	12
Correction: TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNFα in LPS-stimulated macrophages	12
Inverted apicobasal polarity in health and disease	11
First person – Laryssa de Liz	11
Inflammatory macrophage to hepatocyte signals can be prevented by extracellular vesicle reprogramming	11
The roles of the microtubule cytoskeletal network in cardiac mechanobiology	11
A dual-purification system to isolate mitochondrial subpopulations	11
Elimination of aberrantly specified cell clones is independent of interfacial Myosin II accumulation	11
Paclitaxel compromises nuclear integrity in interphase through SUN2-mediated cytoskeletal coupling	11
Fission yeast Duc1 links to ER–PM contact sites and influences PM lipid composition and cytokinetic ring anchoring	11