Journal of Cell Science

Article	Citations
Mammalian stress granules and P bodies at a glance	204
Microautophagy – distinct molecular mechanisms handle cargoes of many sizes	203
The myofibroblast at a glance	171
The cell biologist's guide to super-resolution microscopy	103
Histone variants at a glance	100
Autophagy and endocytosis – interconnections and interdependencies	85
Motor proteins at the mitochondria–cytoskeleton interface	63
Fueling the cytoskeleton – links between cell metabolism and actin remodeling	58
Biomechanical regulation of focal adhesion and invadopodia formation	57
Recent insights into the regulatory networks of NLRP3 inflammasome activation	56
The importance of water and hydraulic pressure in cell dynamics	55
Mitochondrial dynamics during spermatogenesis	54
Cargo transport through the nuclear pore complex at a glance	54
The basement membrane as a structured surface – role in vascular health and disease	52
The ESCRTs – converging on mechanism	52
The formin inhibitor SMIFH2 inhibits members of the myosin superfamily	49
p63-related signaling at a glance	49
Endoplasmic reticulum–mitochondria signaling in neurons and neurodegenerative diseases	45
Talin in mechanotransduction and mechanomemory at a glance	44
The diverse roles and dynamic rearrangement of vimentin during viral infection	44
Extracellular vesicles – propagators of neuropathology and sources of potential biomarkers and therapeutics for neurodegenerative diseases	43
The osteoclast cytoskeleton – current understanding and therapeutic perspectives for osteoporosis	42
The structural basis of intraflagellar transport at a glance	41
Recent insights into peroxisome biogenesis and associated diseases	41
A guide to accurate reporting in digital image processing – can anyone reproduce your quantitative analysis?	38

Notch in mechanotransduction – from molecular mechanosensitivity to tissue mechanostasis	38
Dynamic and cell-specific transport networks for intracellular copper ions	37
Brain endothelial tricellular junctions as novel sites for T cell diapedesis across the blood–brain barrier	37
The multifaceted functions of ATG16L1 in autophagy and related processes	36
The UPRosome – decoding novel biological outputs of IRE1α function	36
Ena/VASP proteins in cell edge protrusion, migration and adhesion	36
A possible role for VPS13-family proteins in bulk lipid transfer, membrane expansion and organelle biogenesis	36
Rhodopsins at a glance	35
Science during lockdown – from virtual seminars to sustainable online communities	35
αvβ8 integrin adhesion and signaling pathways in development, physiology and disease	35
Non-caveolar caveolins – duties outside the caves	34
Protein phosphatase 2A – structure, function and role in neurodevelopmental disorders	34
Quantitative intravital imaging in zebrafish reveals in vivo dynamics of physiological-stress-induced mitophagy	33
Visualizing endogenous Rho activity with an improved localization-based, genetically encoded biosensor	33
Molecular basis for KDEL-mediated retrieval of escaped ER-resident proteins – SWEET talking the COPs	33
Upregulation of APP endocytosis by neuronal aging drives amyloid-dependent synapse loss	33
New insights into non-transcriptional regulation of mammalian core clock proteins	33
A guide to accurate reporting in digital image acquisition – can anyone replicate your microscopy data?	32
Let's get physical – mechanisms of crossover interference	31
The appressorium at a glance	31
Neutral sphingomyelinase 2 controls exosome secretion by counteracting V-ATPase-mediated endosome acidification	31
Diverse cellular functions of barrier-to-autointegration factor and its roles in disease	30
Characterization of the novel mitochondrial genome segregation factor TAP110 in Trypanosoma brucei	29
PDZD8-mediated lipid transfer at contacts between the ER and late endosomes/lysosomes is required for neurite outgrowth	29
Hypothesis-driven quantitative fluorescence microscopy – the importance of reverse-thinking in experimental design	29
FGF2 and IL-1β – explorers of unconventional secretory pathways at a glance	29
Vimentin tunes cell migration on collagen by controlling β1 integrin activation and clustering	29
The flipside of the TOR coin – TORC2 and plasma membrane homeostasis at a glance	29
Pericyte mechanics and mechanobiology	29
The evolution of autophagy proteins – diversification in eukaryotes and potential ancestors in prokaryotes	28
Translation initiation in cancer at a glance	28
Natural killer cell immune synapse formation and cytotoxicity are controlled by tension of the target interface	28
Molecular models of LINC complex assembly at the nuclear envelope	28
Tensins – emerging insights into their domain functions, biological roles and disease relevance	28
mRNA distribution in skeletal muscle is associated with mRNA size	28
Condensation of pericentrin proteins in human cells illuminates phase separation in centrosome assembly	28
Ipomoeassin-F inhibits the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor	27
Mammalian copper homeostasis requires retromer-dependent recycling of the high-affinity copper transporter 1	27
Role of the Sec22b–E-Syt complex in neurite growth and ramification	27
In vivo imaging shows continued association of several IFT-A, IFT-B and dynein complexes while IFT trains U-turn at the tip	27
The oncogenic transcription factor FUS-CHOP can undergo nuclear liquid–liquid phase separation	27
The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy	27
Ferroptosis induces membrane blebbing in placental trophoblasts	27
The role of Mfn2 in the structure and function of endoplasmic reticulum-mitochondrial tethering in vivo	27
An endometrial organoid model of interactions between Chlamydia and epithelial and immune cells	27
Compartmentalization and metabolic regulation of glycolysis	26
Perilipins at a glance	26
Nuclear speckles – a driving force in gene expression	26
On the asymmetric partitioning of nucleocytoplasmic transport – recent insights and open questions	26
Accessory proteins of the zDHHC family of S-acylation enzymes	25

Evolution and insights into the structure and function of the DedA superfamily containing TMEM41B and VMP1	25
Physiological functions and roles in cancer of the proliferation marker Ki-67	24
LFA-1 signals to promote actin polymerization and upstream migration in T cells	24
L-selectin regulates human neutrophil transendothelial migration	24
The journey of Ca2+ through the cell – pulsing through the network of ER membrane contact sites	24
Acute inactivation of retromer and ESCPE-1 leads to time-resolved defects in endosomal cargo sorting	23
The pleiotropic functions of autophagy in metastasis	23
Lipophagy at a glance	23
Centrosome maturation – in tune with the cell cycle	23
A glucose-starvation response governs endocytic trafficking and eisosomal retention of surface cargoes in budding yeast	23
α-Arrestin ARRDC3 tumor suppressor function is linked to GPCR-induced TAZ activation and breast cancer metastasis	22
Rab11 is required for lysosome exocytosis through the interaction with Rab3a, Sec15 and GRAB	22
Luminescence lifetime imaging of three-dimensional biological objects	22
Regulation of hemidesmosome dynamics and cell signaling by integrin α6β4	22
Ras, PI3K and mTORC2 – three's a crowd?	22
Neutrophil transendothelial migration hotspots – mechanisms and implications	22
A three-organelle complex made by wrappER contacts with peroxisomes and mitochondria responds to liver lipid flux changes	21
It takes two to tango – molecular links between plant immunity and brassinosteroid signalling	21
Forcing a growth factor response – tissue-stiffness modulation of integrin signaling and crosstalk with growth factor receptors	21
Spatial distribution of lamin A/C determines nuclear stiffness and stress-mediated deformation	21
Frustrated clathrin-mediated endocytosis – causes and possible functions	21
New insights into FAK structure and function in focal adhesions	21
Ribosome quality control activity potentiates vaccinia virus protein synthesis during infection	20
Combined heterogeneity in cell size and deformability promotes cancer invasiveness	20
The canonical smooth muscle cell marker TAGLN is present in endothelial cells and is involved in angiogenesis	20
The p97–UBXN1 complex regulates aggresome formation	20
Malaria parasite egress at a glance	20
Interaction between VPS13A and the XK scramblase is important for VPS13A function in humans	19
Circulating prostate cancer cells have differential resistance to fluid shear stress-induced cell death	19
The Bardet–Biedl syndrome complex component BBS1 controls T cell polarity during immune synapse assembly	19
The Hob proteins are novel and conserved lipid-binding proteins at ER–PM contact sites	19
Phosphorylation of the AMPA receptor subunit GluA1 regulates clathrin-mediated receptor internalization	19
Ribosome-associated quality control of membrane proteins at the endoplasmic reticulum	19
Emerging functions of cytoskeletal proteins in immune diseases	19
Visualising the cytoskeletal machinery in neuronal growth cones using cryo-electron tomography	19
Insights into animal septins using recombinant human septin octamers with distinct SEPT9 isoforms	19
INPP5E controls ciliary localization of phospholipids and the odor response in olfactory sensory neurons	19
The pivotal role of ERp44 in patrolling protein secretion	19
Turgor-dependent and coronin-mediated F-actin dynamics drive septin disc-to-ring remodeling in the blast fungus Magnaporthe oryzae	19
Nuclear myosins – roles for molecular transporters and anchors	18
A lamin A/C variant causing striated muscle disease provides insights into filament organization	18
Maintenance of complex I and its supercomplexes by NDUF-11 is essential for mitochondrial structure, function and health	18
Importin-9 regulates chromosome segregation and packaging in Drosophila germ cells	18
Cargo sorting at the trans-Golgi network at a glance	18
Coordination of mitochondrial and cellular dynamics by the actin-based motor Myo19	18
Cellular metabolism in the defense against microbes	18
The tumor-suppressive long noncoding RNA DRAIC inhibits protein translation and induces autophagy by activating AMPK	18
Trio family proteins as regulators of cell migration and morphogenesis in development and disease – mechanisms and cellular contexts	18
Tubulin isotypes – functional insights from model organisms	18
Molecular insight into how γ-TuRC makes microtubules	18
YAP, CTGF and Cyr61 are overexpressed in tamoxifen-resistant breast cancer and induce transcriptional repression of ERα	18
TRP channels in health and disease at a glance	18
Hydrostatic pressure prevents chondrocyte differentiation through heterochromatin remodeling	18
Identification of a heat-inducible novel nuclear body containing the long noncoding RNA MALAT1	17
Rab5 regulates macropinocytosis by recruiting the inositol 5-phosphatases OCRL and Inpp5b that hydrolyse PtdIns(4,5)P2	17
FAM209 associates with DPY19L2, and is required for sperm acrosome biogenesis and fertility in mice	17
Mechanical and chemical activation of GPR68 probed with a genetically encoded fluorescent reporter	17
IMC10 and LMF1 mediate mitochondrial morphology through mitochondrion–pellicle contact sites in Toxoplasma gondii	17
Cytoskeletal mechanics and dynamics in the Drosophila syncytial embryo	17
Blockage of bone morphogenetic protein signalling counteracts hypertrophy in a human osteoarthritic micro-cartilage model	17
The role of icIL-1RA in keratinocyte senescence and development of the senescence-associated secretory phenotype	17
Adenine nucleotide translocase regulates airway epithelial metabolism, surface hydration and ciliary function	17
An optogenetic method for interrogating YAP1 and TAZ nuclear–cytoplasmic shuttling	17
Manipulation of selective macroautophagy by pathogens at a glance	17
The F1 loop of the talin head domain acts as a gatekeeper in integrin activation and clustering	17
Advances on the roles of tenascin-C in cancer	17
Depletion of a Toxoplasma porin leads to defects in mitochondrial morphology and contacts with the endoplasmic reticulum	17
Differential cellular responses to adhesive interactions with galectin-8- and fibronectin-coated substrates	16
Direct evidence of cellular transformation by prion-like p53 amyloid infection	16
Dissecting lipid droplet biology with coherent Raman scattering microscopy	16
A novel function for Rab1 and Rab11 during secretory granule maturation	16
Coupling of dynamic microtubules to F-actin by Fmn2 regulates chemotaxis of neuronal growth cones	16
Near-infrared imaging in fission yeast using a genetically encoded phycocyanobilin biosynthesis system	16
Interplay between myofibers and pro-inflammatory macrophages controls muscle damage in mdx mice	16
Enhanced RhoA signalling stabilizes E-cadherin in migrating epithelial monolayers	16
Hit the brakes – a new perspective on the loop extrusion mechanism of cohesin and other SMC complexes	16
The ubiquitin-like modifier FAT10 – much more than a proteasome-targeting signal	16
LRRC23 is a conserved component of the radial spoke that is necessary for sperm motility and male fertility in mice	16
ADAR1 limits stress granule formation through both translation-dependent and translation-independent mechanisms	16
Mitofusin 2 regulates neutrophil adhesive migration and the actin cytoskeleton	16

S-acylation of Orai1 regulates store-operated Ca2+ entry	16
Membrane trafficking in the retinal pigment epithelium at a glance	16
Blood platelet formation at a glance	16
Picornavirus 3C – a protease ensuring virus replication and subverting host responses	16
Control of assembly of extra-axonemal structures: the paraflagellar rod of trypanosomes	16
Ca2+ elevations disrupt interactions between intraflagellar transport and the flagella membrane in Chlamydomonas	15
Data science in cell imaging	15
Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins	15
Structural model of human PORCN illuminates disease-associated variants and drug-binding sites	15
Selective axonal translation of the mRNA isoform encoding prenylated Cdc42 supports axon growth	15
Sex differences in the proliferation of pulmonary artery endothelial cells: implications for plexiform arteriopathy	15
Shedding of ciliary vesicles at a glance	15
Chromosome–nuclear envelope tethering – a process that orchestrates homologue pairing during plant meiosis?	15
A general role for TANGO1, encoded by MIA3, in secretory pathway organization and function	15
Intercellular and intracellular cilia orientation is coordinated by CELSR1 and CAMSAP3 in oviduct multi-ciliated cells	15
Ana1 helps recruit Polo to centrioles to promote mitotic PCM assembly and centriole elongation	15
TORC1 and PKA activity towards ribosome biogenesis oscillates in synchrony with the budding yeast cell cycle	15
The lysosomotrope GPN mobilises Ca2+ from acidic organelles	15
Large organellar changes occur during mild heat shock in yeast	15
Insight into the regulation of axonal transport from the study of KIF1A-associated neurological disorder	14
The role of nuclear Ca2+ in maintaining neuronal homeostasis and brain health	14
Bring it back, bring it back, don't take it away from me – the sorting receptor RER1	14
Polarisome assembly mediates actin remodeling during polarized yeast and fungal growth	14
Roles of the actin cytoskeleton in ciliogenesis	14
Lamellipodia-like actin networks in cells lacking WAVE regulatory complex	14
Emerging evidence for kindlin oligomerization and its role in regulating kindlin function	14
The actin cytoskeleton-MRTF/SRF cascade transduces cellular physical niche cues to entrain the circadian clock	14
Decoupling SARS-CoV-2 ORF6 localization and interferon antagonism	14
MyomiRs and their multifaceted regulatory roles in muscle homeostasis and amyotrophic lateral sclerosis	14
Hijacking of the host cell Golgi by Plasmodium berghei liver stage parasites	14
Stable tug-of-war between kinesin-1 and cytoplasmic dynein upon different ATP and roadblock concentrations	14
Rab7b regulates dendritic cell migration by linking lysosomes to the actomyosin cytoskeleton	14
The surface of lipid droplets constitutes a barrier for endoplasmic reticulum-resident integral membrane proteins	14
The prophase oocyte nucleus is a homeostatic G-actin buffer	14
Fibronectin Extra Domains tune cellular responses and confer topographically distinct features to fibril networks	14
Chlamydomonas FAP70 is a component of the previously uncharacterized ciliary central apparatus projection C2a	13
Genetic compensation for cilia defects in cep290 mutants by upregulation of cilia-associated small GTPases	13
Cargo adapters expand the transport range of intraflagellar transport	13
Fibroblastic reticular cell response to dendritic cells requires coordinated activity of podoplanin, CD44 and CD9	13
Cell-to-cell and genome-to-genome variability of adenovirus transcription tuned by the cell cycle	13
Bacteria- and host-derived extracellular vesicles – two sides of the same coin?	13
Dynamic remodeling of ribosomes and endoplasmic reticulum in axon terminals of motoneurons	13
EVI/WLS function is regulated by ubiquitylation and is linked to ER-associated degradation by ERLIN2	13
Mechanosensitive expression of lamellipodin promotes intracellular stiffness, cyclin expression and cell proliferation	13
Expression analysis and function of mitochondrial genome-encoded microRNAs	13
Local translation in perisynaptic and perivascular astrocytic processes – a means to ensure astrocyte molecular and functional polarity?	13
Tyrosine kinase-independent actions of DDR2 in tumor cells and cancer-associated fibroblasts influence tumor invasion, migration and metastasis	13
Cytoplasmic factories for axonemal dynein assembly	13
Non-muscle myosin 2 at a glance	13
ApoE4 disrupts interaction of sortilin with fatty acid-binding protein 7 essential to promote lipid signaling	13
Evidence for macromolecular crowding as a direct apoptotic stimulus	13
A dual role of YAP in driving TGFβ-mediated endothelial-to-mesenchymal transition	13
Desmosome dualism – most of the junction is stable, but a plakophilin moiety is persistently dynamic	13
Non-canonical argonaute loading of extracellular vesicle-derived exogenous single-stranded miRNA in recipient cells	13
ULK1-mediated phosphorylation regulates the conserved role of YKT6 in autophagy	13
Efficient genome editing by CRISPR-Mb3Cas12a in mice	13
Supply chain logistics – the role of the Golgi complex in extracellular matrix production and maintenance	13
Innate immune receptor clustering and its role in immune regulation	13
Lipid droplets form a network interconnected by the endoplasmic reticulum through which their proteins equilibrate	13
Emerin regulation of nuclear stiffness is required for fast amoeboid migration in confined environments	13
Lysosomal TRPML1 regulates mitochondrial function in hepatocellular carcinoma cells	12
Genome-wide imaging screen uncovers molecular determinants of arsenite-induced protein aggregation and toxicity	12
Septin-microtubule association via a motif unique to isoform 1 of septin 9 tunes stress fibers	12
Mitochondrial Ca2+ uniporter haploinsufficiency enhances long-term potentiation at hippocampal mossy fibre synapses	12
Diverse mechanisms regulate contractile ring assembly for cytokinesis in the two-cell C. elegans embryo	12
Nuclear localization of p65 reverses therapy-induced senescence	12
Intracellular flow cytometric lipid analysis – a multiparametric system to assess distinct lipid classes in live cells	12
Smaug1 membrane-less organelles respond to AMPK and mTOR and affect mitochondrial function	12
Selective microautophagy of proteasomes is initiated by ESCRT-0 and is promoted by proteasome ubiquitylation	12
Single-cell imaging of ERK and Akt activation dynamics and heterogeneity induced by G-protein-coupled receptors	12
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer	12
Ultrastructure expansion microscopy reveals the cellular architecture of budding and fission yeast	12
Identification of mutants with increased variation in cell size at onset of mitosis in fission yeast	12
Viral use and subversion of membrane organization and trafficking	12
Vacuolar protein Tag1 and Atg1–Atg13 regulate autophagy termination during persistent starvation in S. cerevisiae	12
Emerging views of genome organization in Archaea	12
Emerging insights into serine/threonine-specific phosphoprotein phosphatase function and selectivity	12
Concurrent depletion of Vps37 proteins evokes ESCRT-I destabilization and profound cellular stress responses	12
Managing risky assets – mitophagy in vivo	12
Dissecting the PRSS37 interactome and potential mechanisms leading to ADAM3 loss in PRSS37-null sperm	11
Conserved cholesterol-related activities of Dispatched 1 drive Sonic hedgehog shedding from the cell membrane	11
Organization and dynamics of the cortical complexes controlling insulin secretion in β-cells	11
MITOL-mediated DRP1 ubiquitylation and degradation promotes mitochondrial hyperfusion in a CMT2A-linked MFN2 mutant	11
Metformin inactivates the cGAS-STING pathway through autophagy and suppresses senescence in nucleus pulposus cells	11
me31B regulates stem cell homeostasis by preventing excess dedifferentiation in the Drosophila male germline	11
An SNX10-dependent mechanism downregulates fusion between mature osteoclasts	11
The role of lipid rafts in vesicle formation	11
A quantitative study of the Golgi retention of glycosyltransferases	11
Chick cranial neural crest cells release extracellular vesicles that are critical for their migration	11
When light meets biology – how the specimen affects quantitative microscopy	11
Oncogenic gain of function due to p53 amyloids occurs through aberrant alteration of cell cycle and proliferation	11
De novo formation of early endosomes during Rab5-to-Rab7a transition	11
Tumour-directed microenvironment remodelling at a glance	11
Co-transport of the nuclear-encoded Cox7c mRNA with mitochondria along axons occurs through a coding-region-dependent mechanism	11
Exploring cell and tissue mechanics with optical tweezers	11