OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Experimental Medicine is 57. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL	237
Early innate role for CD8αα+ cells in tuberculosis	228
Primary tumor–derived systemic nANGPTL4 inhibits metastasis	210
Prenatally derived macrophages support choroidal health and decline in age-related macular degeneration	200
The microbial one-hit wonder	187
Antibody feedback contributes to facilitating the development of Omicron-reactive memory B cells in SARS-CoV-2 mRNA vaccinees	179
Inhibition of astrocytic DRD2 suppresses CNS inflammation in an animal model of multiple sclerosis	174
High burden of viruses and bacterial pathobionts drives heightened nasal innate immunity in children	163
Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro–T cells	161
The pathogenic role of retinoid nuclear receptor signaling in cancer and metabolic syndromes	144
An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis	137
Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge	126
SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly	122
IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation	121
Intestinal epithelial c-Maf expression determines enterocyte differentiation and nutrient uptake in mice	121
B cell receptor ligation induces IgE plasma cell elimination	118
Differential IL-12 signaling induces human natural killer cell activating receptor-mediated ligand-specific expansion	110
Sphingosine 1-phosphate receptor 5 (S1PR5) regulates the peripheral retention of tissue-resident lymphocytes	110
Protection of ischemic white matter and oligodendrocytes in mice by 3K3A-activated protein C	109
Inflammation as a regulator of hematopoietic stem cell function in disease, aging, and clonal selection	106
Host factor TIMP1 sustains long-lasting myeloid-biased hematopoiesis after severe infection	100
RORγt eTACs mediate oral tolerance and Treg induction	96
ASC deglutathionylation is a checkpoint for NLRP3 inflammasome activation	95
Human STAT3 variants underlie autosomal dominant hyper-IgE syndrome by negative dominance	92
TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion	84

Making memories with Bcl-6	82
Implication of folate deficiency in CYP2U1 loss of function	82
Loss of ATG7 in microglia impairs UPR, triggers ferroptosis, and weakens amyloid pathology control	80
Systems-level conservation of the proximal TCR signaling network of mice and humans	79
Lymphatic chain gradients regulate the magnitude and heterogeneity of T cell responses to vaccination	79
IFNγ score–based neoadjuvant immunotherapy for stage III melanoma	77
NFAT5 governs cellular plasticity-driven resistance to KRAS-targeted therapy in pancreatic cancer	77
Challenges in TB research	76
pDCs, type 1 IFN, and the female predileXion of SSc	76
Correction: Segmented filamentous bacteria–induced epithelial MHCII regulates cognate CD4+ IELs and epithelial turnover	75
Posttranscriptional regulation of ILC2 homeostatic function via tristetraprolin	75
TIGIT mediates activation-induced cell death of ILC2s during chronic airway allergy	75
A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice	74
The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression	74
Dual role of vascular endothelial growth factor-C in post-stroke recovery	69
Role of adipose tissue macrophages in obesity-related disorders	67
Non-professional efferocytosis of Salmonella-infected intestinal epithelial cells in the neonatal host	66
CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17	65
Transit-amplifying cells control R-spondins in the mouse crypt to modulate intestinal stem cell proliferation	65
CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy	65
Hypoxia induces adrenomedullin from lung epithelia, stimulating ILC2 inflammation and immunity	64
Obesity alters monocyte developmental trajectories to enhance metastasis	64
A high OXPHOS CD8 T cell subset is predictive of immunotherapy resistance in melanoma patients	63
Single cell analysis of M. tuberculosis phenotype and macrophage lineages in the infected lung	62
CD150-dependent hematopoietic stem cell sensing of Brucella instructs myeloid commitment	62
Extracellular vesicle– and particle-mediated communication shapes innate and adaptive immune responses	61
Protein arginine methyltransferase 1 regulates B cell fate after positive selection in the germinal center in mice	60
MYO1F in neutrophils is required for the response to immune checkpoint blockade therapy	60
Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner	59
Spatiotemporal dynamics of fetal liver hematopoietic niches	59
Tingible body macrophages: Gargantuan chameleons of the germinal center	58
Gut epithelial IL-27 confers intestinal immunity through the induction of intraepithelial lymphocytes	58
MYC is a clinically significant driver of mTOR inhibitor resistance in breast cancer	57
Functional specialization of short-lived and long-lived macrophage subsets in human tonsils	57
A twist in the tail: Of T cell subsets and disease	57
T2B or not to B: Calming neutrophils offshore	57