OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Experimental Medicine is 56. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
S1PR1, an endothelial-immune influencer	258
Epitope and HLA specificity of human TCRs against Plasmodium falciparum circumsporozoite protein	223
The pathogenic role of retinoid nuclear receptor signaling in cancer and metabolic syndromes	183
Prenatally derived macrophages support choroidal health and decline in age-related macular degeneration	171
ASC deglutathionylation is a checkpoint for NLRP3 inflammasome activation	134
IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation	126
Antibody feedback contributes to facilitating the development of Omicron-reactive memory B cells in SARS-CoV-2 mRNA vaccinees	124
Differential IL-12 signaling induces human natural killer cell activating receptor-mediated ligand-specific expansion	118
Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge	116
The microbial one-hit wonder	113
SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly	106
Intestinal epithelial c-Maf expression determines enterocyte differentiation and nutrient uptake in mice	103
Early innate role for CD8αα+ cells in tuberculosis	98
Protection of ischemic white matter and oligodendrocytes in mice by 3K3A-activated protein C	98
Primary tumor–derived systemic nANGPTL4 inhibits metastasis	94
An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis	85
RORγt eTACs mediate oral tolerance and Treg induction	85
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL	84
Sphingosine 1-phosphate receptor 5 (S1PR5) regulates the peripheral retention of tissue-resident lymphocytes	83
Inhibition of astrocytic DRD2 suppresses CNS inflammation in an animal model of multiple sclerosis	82
Host factor TIMP1 sustains long-lasting myeloid-biased hematopoiesis after severe infection	81
B cell receptor ligation induces IgE plasma cell elimination	79
High burden of viruses and bacterial pathobionts drives heightened nasal innate immunity in children	79
A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice	77
TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion	77

ALK2/3 recruitment to the immunological synapse is required for T cell activation and death	77
Dual role of vascular endothelial growth factor-C in post-stroke recovery	71
Lymphatic chain gradients regulate the magnitude and heterogeneity of T cell responses to vaccination	71
pDCs, type 1 IFN, and the female predileXion of SSc	70
Challenges in TB research	69
The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression	69
NFAT5 governs cellular plasticity-driven resistance to KRAS-targeted therapy in pancreatic cancer	68
CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy	68
Loss of ATG7 in microglia impairs UPR, triggers ferroptosis, and weakens amyloid pathology control	66
IFNγ score–based neoadjuvant immunotherapy for stage III melanoma	64
Correction: ICAM-1 controls development and function of ILC2	63
Non-professional efferocytosis of Salmonella-infected intestinal epithelial cells in the neonatal host	63
Implication of folate deficiency in CYP2U1 loss of function	63
Correction: Segmented filamentous bacteria–induced epithelial MHCII regulates cognate CD4+ IELs and epithelial turnover	63
Transit-amplifying cells control R-spondins in the mouse crypt to modulate intestinal stem cell proliferation	62
TIGIT mediates activation-induced cell death of ILC2s during chronic airway allergy	62
Obesity alters monocyte developmental trajectories to enhance metastasis	62
Systems-level conservation of the proximal TCR signaling network of mice and humans	62
Making memories with Bcl-6	62
Role of adipose tissue macrophages in obesity-related disorders	62
Hypoxia induces adrenomedullin from lung epithelia, stimulating ILC2 inflammation and immunity	62
CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17	61
Posttranscriptional regulation of ILC2 homeostatic function via tristetraprolin	60
A high OXPHOS CD8 T cell subset is predictive of immunotherapy resistance in melanoma patients	60
Amino acid availability acts as a metabolic rheostat to determine the magnitude of ILC2 responses	60
Nina Cabezas Wallscheid: Enjoying the freedom to decide my research path	59
Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner	59
A twist in the tail: Of T cell subsets and disease	57
Augmenting neurogenesis rescues memory impairments in Alzheimer’s disease by restoring the memory-storing neurons	56
Tingible body macrophages: Gargantuan chameleons of the germinal center	56
Michelle Linterman: We are always learning	56