OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Experimental Medicine is 55. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Early innate role for CD8αα+ cells in tuberculosis	294
S1PR1, an endothelial-immune influencer	223
ALK2/3 recruitment to the immunological synapse is required for T cell activation and death	158
Differential IL-12 signaling induces human natural killer cell activating receptor-mediated ligand-specific expansion	141
Local gene editing of fibroblasts in tumors reveals a new cancer-associated fibroblast state	133
Inhibition of astrocytic DRD2 suppresses CNS inflammation in an animal model of multiple sclerosis	124
High burden of viruses and bacterial pathobionts drives heightened nasal innate immunity in children	114
Common cold embecovirus imprinting primes broadly neutralizing antibody responses to SARS-CoV-2 S2	113
Primary tumor–derived systemic nANGPTL4 inhibits metastasis	107
Intestinal epithelial c-Maf expression determines enterocyte differentiation and nutrient uptake in mice	106
SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly	105
Epitope and HLA specificity of human TCRs against Plasmodium falciparum circumsporozoite protein	104
Prenatally derived macrophages support choroidal health and decline in age-related macular degeneration	96
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL	96
B cell receptor ligation induces IgE plasma cell elimination	96
Host factor TIMP1 sustains long-lasting myeloid-biased hematopoiesis after severe infection	93
Antibody feedback contributes to facilitating the development of Omicron-reactive memory B cells in SARS-CoV-2 mRNA vaccinees	90
RORγt eTACs mediate oral tolerance and Treg induction	90
IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation	88
The pathogenic role of retinoid nuclear receptor signaling in cancer and metabolic syndromes	87
An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis	87
A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice	83
IFNγ score–based neoadjuvant immunotherapy for stage III melanoma	83
T cell engagers emerge as a compelling therapeutic modality	83
Non-professional efferocytosis of Salmonella-infected intestinal epithelial cells in the neonatal host	83

Heterozygous human JAK2V617F activates AhR to drive essential thrombocythemia and promote thrombosis	82
Obesity alters monocyte developmental trajectories to enhance metastasis	81
The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression	80
Role of adipose tissue macrophages in obesity-related disorders	80
Lymphatic chain gradients regulate the magnitude and heterogeneity of T cell responses to vaccination	75
Challenges in TB research	74
CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy	73
pDCs, type 1 IFN, and the female predileXion of SSc	73
Correction: ICAM-1 controls development and function of ILC2	73
Correction: Segmented filamentous bacteria–induced epithelial MHCII regulates cognate CD4+ IELs and epithelial turnover	72
Hypoxia induces adrenomedullin from lung epithelia, stimulating ILC2 inflammation and immunity	71
Transit-amplifying cells control R-spondins in the mouse crypt to modulate intestinal stem cell proliferation	70
Dual role of vascular endothelial growth factor-C in post-stroke recovery	70
CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17	69
TIGIT mediates activation-induced cell death of ILC2s during chronic airway allergy	69
NFAT5 governs cellular plasticity-driven resistance to KRAS-targeted therapy in pancreatic cancer	68
Loss of ATG7 in microglia impairs UPR, triggers ferroptosis, and weakens amyloid pathology control	68
Nina Cabezas Wallscheid: Enjoying the freedom to decide my research path	66
Michelle Linterman: We are always learning	66
How decreasing T cell signaling unexpectedly results in autoimmunity	66
A twist in the tail: Of T cell subsets and disease	64
Amino acid availability acts as a metabolic rheostat to determine the magnitude of ILC2 responses	63
CD150-dependent hematopoietic stem cell sensing of Brucella instructs myeloid commitment	63
Tingible body macrophages: Gargantuan chameleons of the germinal center	63
IEC-intrinsic IL-1R signaling holds dual roles in regulating intestinal homeostasis and inflammation	62
Memory B cell responses to Omicron subvariants after SARS-CoV-2 mRNA breakthrough infection in humans	60
Rethinking disomy: Autosomal expression bias	58
Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner	58
Targeting infection-specific peptides in immunopeptidomics studies for vaccine target discovery	57
Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses	56
MYO1F in neutrophils is required for the response to immune checkpoint blockade therapy	55
Pleiotrophin drives a prometastatic immune niche in breast cancer	55