OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Experimental Medicine is 57. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
ALK2/3 recruitment to the immunological synapse is required for T cell activation and death	333
Host factor TIMP1 sustains long-lasting myeloid-biased hematopoiesis after severe infection	268
Intestinal epithelial c-Maf expression determines enterocyte differentiation and nutrient uptake in mice	208
Early innate role for CD8αα+ cells in tuberculosis	200
Primary tumor–derived systemic nANGPTL4 inhibits metastasis	160
Epitope and HLA specificity of human TCRs against Plasmodium falciparum circumsporozoite protein	156
Differential IL-12 signaling induces human natural killer cell activating receptor-mediated ligand-specific expansion	132
S1PR1, an endothelial-immune influencer	113
Prenatally derived macrophages support choroidal health and decline in age-related macular degeneration	113
Common cold embecovirus imprinting primes broadly neutralizing antibody responses to SARS-CoV-2 S2	107
SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly	104
Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge	102
B cell receptor ligation induces IgE plasma cell elimination	97
The pathogenic role of retinoid nuclear receptor signaling in cancer and metabolic syndromes	93
High burden of viruses and bacterial pathobionts drives heightened nasal innate immunity in children	92
Antibody feedback contributes to facilitating the development of Omicron-reactive memory B cells in SARS-CoV-2 mRNA vaccinees	91
IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation	88
RORγt eTACs mediate oral tolerance and Treg induction	85
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL	85
Inhibition of astrocytic DRD2 suppresses CNS inflammation in an animal model of multiple sclerosis	84
An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis	81
IFNγ score–based neoadjuvant immunotherapy for stage III melanoma	80
Correction: ICAM-1 controls development and function of ILC2	78
NFAT5 governs cellular plasticity-driven resistance to KRAS-targeted therapy in pancreatic cancer	77
Systems-level conservation of the proximal TCR signaling network of mice and humans	75

Heterozygous human JAK2V617F activates AhR to drive essential thrombocythemia and promote thrombosis	75
Challenges in TB research	75
CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17	74
pDCs, type 1 IFN, and the female predileXion of SSc	74
Hypoxia induces adrenomedullin from lung epithelia, stimulating ILC2 inflammation and immunity	73
Lymphatic chain gradients regulate the magnitude and heterogeneity of T cell responses to vaccination	73
Obesity alters monocyte developmental trajectories to enhance metastasis	72
Correction: Segmented filamentous bacteria–induced epithelial MHCII regulates cognate CD4+ IELs and epithelial turnover	72
The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression	72
Non-professional efferocytosis of Salmonella-infected intestinal epithelial cells in the neonatal host	70
CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy	70
A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice	68
TIGIT mediates activation-induced cell death of ILC2s during chronic airway allergy	68
Transit-amplifying cells control R-spondins in the mouse crypt to modulate intestinal stem cell proliferation	68
Loss of ATG7 in microglia impairs UPR, triggers ferroptosis, and weakens amyloid pathology control	65
T cell engagers emerge as a compelling therapeutic modality	65
Role of adipose tissue macrophages in obesity-related disorders	64
Dual role of vascular endothelial growth factor-C in post-stroke recovery	64
Somatic gain-of-function mutations in BUD13 promote oncogenesis by disrupting Fbw7 function	63
How decreasing T cell signaling unexpectedly results in autoimmunity	63
MYO1F in neutrophils is required for the response to immune checkpoint blockade therapy	62
Michelle Linterman: We are always learning	62
Nina Cabezas Wallscheid: Enjoying the freedom to decide my research path	62
Targeting infection-specific peptides in immunopeptidomics studies for vaccine target discovery	61
Human autoantibodies underlying infectious diseases	61
A twist in the tail: Of T cell subsets and disease	61
Tingible body macrophages: Gargantuan chameleons of the germinal center	61
Protein arginine methyltransferase 1 regulates B cell fate after positive selection in the germinal center in mice	61
Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner	60
Protective fibroblastic niches in secondary lymphoid organs	59
Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses	59
Oral antigen exposure under costimulation blockade induces Treg cells to establish immune tolerance	58
CD150-dependent hematopoietic stem cell sensing of Brucella instructs myeloid commitment	57
CXCR4+ Treg cells control serum IgM levels and natural IgM autoantibody production by B-1 cells in the bone marrow	57
Pleiotrophin drives a prometastatic immune niche in breast cancer	57