Journal of Heterocyclic Chemistry

Article	Citations
Issue Information	69
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	52
Novel ferrocene cyclopalladated compounds: Synthesis, and in‐vitro antitumor activity study	48
Synthesis and molecular modeling of some novel hydroxypyrone derivatives as antidermatophytic agents	36
Combination of N‐amino‐1,2,4‐triazole and 4‐hydroxy‐3,5‐dinitropyrazole for the synthesis of high performing explosives	35
Solvent‐free Darzens condensation of 3‐chlorooxindoles with aryl aldehydes for diastereoselective construction of spiro‐epoxyoxindoles by grinding	31
Issue Information	29
Retraction statement: Facile synthesis of two oxocan derivatives using some chemical strategies	28
Synthesis of novel amide/amino acid functionalized pyrazolo[3,4‐b]pyridine derivatives; their anticancer activity and docking studies	27
One‐pot three‐component synthesis of novel chromeno[3,2‐c]pyridine‐1,9(2H)‐diones by using SnCl2⋅2H2O as catalyst	26
Synthetic Approaches Toward Imidazo‐Fused Heterocycles: A Comprehensive Review	26
A quick and easy access to a series of thiocyanated enaminones and 2‐iminothiazolones using PIDA under mild conditions	24
Ultrasound‐promoted1,3‐dipolarcycloaddition of azomethine yields for synthesis of dispiropyrrolidineoxindole derivatives in hexyltriphenylphosphonium bromide as an ionic liquid,	24
Hybrid of the 1,2,3‐triazole nucleus and sesquiterpene skeleton as a potential antitumor agent: Hemisynthesis, molecular structure, Hirshfeld surface analysis, density functional theory, and in vitro	24
Facile access to 2‐amino‐4‐aryl‐5H‐chromeno[4,3‐b]pyridine‐3‐carbonitriles through a strategy of one‐pot Michael/cyclization reaction	24
Novel angularly substituted [1,4]thiazino[3,4‐a]isoquinoline carboxylic acids prepared by cyclic imine‐cyclic anhydride reaction	22
NiO‐Nanoparticles as green catalyst for an efficient synthesis of 4‐iminopyrido[1,2‐a]pyrimidine fluorophores via one pot cyclization of α‐aminonicotinonitrile	21
Unprecedented, catalyst‐free, and rapid one‐pot, three‐component green synthesis of substituted 3‐hydroxy‐2‐oxindoles in water	20
Synthesis and biological assessment of some fused Pyran derivatives	19
A regiospecific fischer indole reaction with 3‐oxo‐24‐nor‐allobetulin	19
Palladium‐Catalyzed Synthesis of Pyrrolo[1,2‐α]Pyrazines From N‐Phenacyl Pyrrole‐2‐Carbonitriles and Aryl Boronic Acids	19
Synthesis, antimicrobial activity, and molecular docking studies of new fused pyrimidinethiones	18
Synthesis, and reverse screening of 6‐(3,4,5‐trimethoxyphenyl)pyrimidine‐5‐carbonitrile derivatives as anticancer agents: Part‐II	18
Microwave‐Assisted One‐Pot Synthesis of 1,5‐Benzodiazepine Derivatives Using Novel ZnFe2O4.Cu(OH)2 Magnetic Nanocomposite as Heterogeneous Cataly	18

Synthesis of substituted 5‐aryl‐2,3‐dihydropyrazine 1,4‐dioxides based on condensation of N,N′‐(2,3‐dimethylbutane‐2,3‐diyl)bis(hydroxylamine) with various arylglyoxals	18
[3+2] cycloaddition synthesis of new (nicotinonitrile‐chromene)‐based bis(pyrazole) hybrids as potential acetylcholinesterase inhibitors	17
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Introduction of the Acyl Group at the C7 Position of Indole via N‐Acyl Indole Photo‐Fries Rearrangement Under UV‐C	17
New Corono Asymmetrical N‐Bis‐Heterocyclic Bis‐Imidazolium Macrocycle Salt, Preliminary Physicochemical Studies, X‐Ray Structures, and Biological Evaluation	17
Trifluorodiazoethane: A versatile building block to access trifluoromethylated heterocycles	16
Catalyst‐free one‐pot three‐component rapid synthesis of polysubstituted pyrroles by liquid‐assisted grinding	16
A synthetic strategy for the preparation of alkoxy‐functionalized bis‐1,2,4‐triazinyl‐2,6‐pyridines	16
	16
Photoinduced 6π‐electrocyclization of 2,5‐dichlorothiophene containing benzofuranylacrylonitriles as efficient method for the generation of hydrogen chloride	16
The applications of β‐keto amides for heterocycle synthesis	16
Synthesis and herbicidal activity of pyrimidyl‐1,2,4‐triazole derivatives containing aryl sulfonyl moiety	16
Synthesis of 1,3‐oxazepine derivatives via tandem reaction of 5‐benzylidine Meldrum's acids with TosMIC in presence of potassium carbonate	15
Synthesis and characterizations of some new selenolo[2,3‐b]quinoxaline derivatives	15
New metal free organic dyes incorporating heterocyclic Benzofuran core as conjugated spacer: Synthesis, Opto‐electrochemical, DFT and DSSC studies	15
Cycloaddition or Metathesis: Selectivity in a Series of Indole‐2,3‐Quinodimethane Derivatives	15
Natural and Synthetic Decahydroquinolines: Synthesis Strategies and Biological Activity	15
Iron‐catalyzed construction of cyanomethylated thiohydantoins by cross‐dehydrogenative C(sp3)‐C(sp3) coupling	15
An approach for the diastereoselective synthesis of (R)‐(+)‐methyl pipecolate and (+)‐dextro‐erythrophacetoperane from (S)‐(−)‐methylbenzylamine	15
Retraction statement: Facile synthesis of two oxocan derivatives using some chemical strategies	15
Synthesis and evaluation of the biological activities of novel hybrid isoindol‐1,3‐dione containing an aziridine unit	14
An efficient organopromotor L‐arginine facilitated synthesis of thiazolo[3,2‐a]pyrimidine derivatives in EtOH:H2O solvent	14
Visible‐light photoredox catalyzed synthesis of tetrahydrobenzofuranone: Oxidative [3 + 2] cycloaddition of dicarbonyl and alkene	14
New edaravone analogs incorporated with N‐benzylthiazole moiety: Multistep chemical synthesis, in vitro cytotoxicity with pRIPK3 inhibitory activities, and molecular docking	14
Discovery of Promising Sulfadiazine Derivatives With Anti‐Proliferative Activity Against Tumor Cell Lines	14
A “One‐Pot” Metal‐Free Synthesis and Evaluation of Antiproliferative Activity of Diversely Functionalized Pyrrolidine‐2‐Ones	14
Saccharin‐catalyzed multicomponent cascade reactions for the synthesis of 1,2,3,4,6‐pentasubstituted piperidines	13
Novel pyrazole‐biphenyl‐carboxamides for SARS‐CoV2 entry‐level restriction and microbial infections	13
Long alkoxy substituted N2S2 porphyrins for liquid crystalline property	13
Efficient preparation of (S)‐2‐(3,5‐dimethylphenyl)pyrrolidine via a recycle process of resolution	13
Utility of pyrrole‐2‐thioacetohydrazide in synthesis of new heterocyclic compounds with promising antimicrobial activities and molecular docking studies	13
Thiazolidinedione‐Pyrimidine Hybrid as Potential Antidiabetic Agents and Their Cardioprotective Effect	13
Synthesis of novel Schiff bases as stable enol‐imine‐containing diazene bonds and pyrimidines using trimethinium salts	12
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Synthesis of arylidene‐based benzoxazine derivatives as promising antimicrobial materials	12
Manipulating sensitivities of planar oxadiazole‐based high performing energetic materials	12
Synthesis and Application of Azide‐Incorporated Copper‐Chelating Peptides for Efficient Click Conjugation Reaction	12
Synthesis of Novel 6H‐Furo[3,2‐e]Indole Derivatives via One‐Pot Three Component Reactions	12
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Design, synthesis, and pesticidal activities of novel pyrimidin‐4‐amine derivatives containing trifluoroethyl sulfide moiety	11
Synthesis and bioactivity evaluation of 5‐trifluoromethyl‐1H‐pyrazole‐4‐carboxamide derivatives as potential anticancer and antifungal agents	11
Imidazo[1,2,4]triazolone and fused imidazo[1,2,4]triazolone derivatives: Synthesis, in vitro anticancer screening, CDK2 inhibitory activity, and molecular modeling studies	11
Research progress of oxazole derivatives in the discovery of agricultural chemicals	11
Thermal [2+2] Cycloaddition of Dihydropyrroles and Dimethyl Acetylenedicarboxylate	11
Design, synthesis, antimicrobial evaluation, and in‐silico studies of some 4‐thiazolidinone hybrids bearing coumarin and pyridine moieties	11
A Simple, Economical, and Green Protocol for the Synthesis of Benzyl‐Quinoline Analogues by Grinding	11
Investigation of some new main group metal complexes of hydrazine and 2‐mercaptopyridine‐3‐carboxylic acid mixed–ligands	10
Overview of Hydroxychloroquine and Remdesivir on severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)	10
A Sequential One‐Pot Synthesis of Quinoline‐Fused Benzoxe(Aze)pines via Intramolecular Reductive Heck Cyclisation	10
Issue Information	10

Convenient synthesis and antibacterial evaluation of new bipyrazolyl and pyrazolopyridazine derivatives utilizing 4‐acetyl‐5‐methyl‐N‐phenyl‐1‐(p‐tolyl)‐1H‐p	10
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Issue Information	9
Design, synthesis, biological evaluation, and molecular docking studies of some novel N,N‐dimethylaminopropoxy‐substituted aurones	9
Toward understanding the regioselectivity of the one‐pot reaction of phenylene diamines with aldehydes and cyclopentadiene (Povarov reaction). Combined experimental and theoretical approaches	9
Synthesis, characterization and crystal structure of some novel partially hydrogenated isoquinolines and their fused heterocyclic systems	9
Facile synthesis and antimicrobial activity of bis(fused 4H‐pyrans) incorporating piperazine as novel hybrid molecules: Michael's addition approach	9
Synthetic strategies of phenazine derivatives: A review	9
Arylhydrazine salt‐selenium: A novel and efficient reagent system for arylselenenylation of unprotected uracil and its derivatives	9
Synthesis and biological evaluation of baloxavir marboxil analogs for the treatment of influenza A (H1N1) virus	9
Neat multicomponent assembly of highly functionalized Acenaphtho[1,2‐b]pyrroles, in vitro evaluation for antioxidant and cytotoxic activities	9
Visible‐Light Induced Rose Bengal Photocatalyzed One‐Pot Environmentally Sustainable Multicomponent Synthesis of Substituted Pyrazolo[3,4‐b]Quinolin‐5‐Ones	9
Polycyclic Dicationic Heteroaromatic Compounds From One‐Step Multiple Condensation Reactions: Synthesis and Reactivity	8
Regio Selective Synthesis of Pyrazole Derivatives of 5‐Chloro‐2‐Methoxy Phenyl Hydrazide and Their Biological Evaluation	8
Synthesis, antimicrobial activity, and in silico studies of fluoroquinolones bearing 1,3,4‐oxadiazolyl‐triazole derivatives	8
Issue Information	8
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Synthesis a group of 5(6)‐substituted benzimidazole Zn(II) and Co(II) complexes and investigation their cytotoxic and antimicrobial activities	8
Facile synthesis and anticancer activity of tetrazolyl‐benzothiazole derivatives	8
Reactivity of pyrimidinylphosphazenes with acetylenic esters: Competitive [4 + 2] and [2 + 2] tandem cycloaddition or retro‐cycloaddition approaches	8
Radical synthesis of dihydropyrano[2,3‐c]pyrazoles using acridine yellow G as a photo‐induced electron transfer photocatalyst	8
Synthesis, characterization, anti‐proliferative evaluation, and molecular docking study of some new N‐(1, 3‐dioxoisoindolin‐4‐yl)acetamide derivatives	8
Synthesis of Alpha‐Acyloxy‐(1,2,5‐Oxadiazole‐2‐Oxide) Carboxamides via Passerini Multicomponent Reaction. Evaluation of Nitric Oxide‐Releasing and Anti‐Proliferative Properties	8
Synthesis of new thiazine and thiazole derivatives via cyclization reactions; investigating their electronic properties and determination of antioxidant properties	8
Direct synthesis of β2,3‐amino acid from β‐hydroxycarbamides: Implication in the synthesis of azumamide analogs and conformational analysis	8
Design, Synthesis, In Vitro Evaluation of New Tetrahydrooxazolo [5′,4′:4,5]Pyrimido[1,2‐a]Azepinone Derivatives as Anticancer Agents	8
Synthesis and Characterization of Benzo[6,7]Cyclohepta[1,2‐b]Pyrazolo[4,3‐e]Pyridines	8
N‐Azidoethyl azoles through N‐alkylation under highly harmonized reaction conditions: Synthesis, characterization, and complexation as energetic coordination compounds	8
Synthesis and Cellular Evaluation of Some Oxepino‐ and Pyranoxanthone Derivatives as Antitumor Agents: A Comparative Study	8
Dimethyl‐1,4‐Dithiines From 2‐Chloroprop‐2‐Enylisothiouronium Salt in KOH/Hydrazine Hydrate Medium: Experiment and Quantum Chemical Study	8
Kilogram synthesis of pinoxaden	8
An operationally simple, one‐pot, convenient synthesis, and in vitro anti‐inflammatory activity of some new spirotriazolotriazine derivatives	8
Issue Information	8
CuI–Zn(OAc)2 Catalyzed Selective CC Bond Cleavage of 1,3‐Diketones/β‐Ketoester for the Formation of Quinazolin‐4(3H)‐Ones: A Fast, Solvent‐Free, Syn	8
Synthesis of Benzofuran‐Based Hybrid Molecules: Molecular Docking and Antibacterial Activity Against Pseudomonas aeruginosa	8
Synthesis of Terminal Alkenylindolines via Rhodium‐Catalyzed Direct CH Alkenylation With Alkenyl Borates	8
Multicomponent synthesis of spiro 1,3,4‐thiadiazolines with anticancer activity by using deep eutectic solvent under microwave irradiation	7
Issue Information	7
An efficient and green synthesis of multi‐heteroatom heterocycles via a three components reaction in acetic acid/aqueous condition	7
An efficient synthesis of new 3,5‐bis(2‐arylthiazol‐4‐yl)‐1,2,4‐oxadiazole derivatives and their antimicrobial evaluation	7
Recyclization of 3‐substituted‐6,8‐dimethylchromones with some heterocyclic enamines: Spectroscopic, quantum calculations (HOMO–LUMO, MEP, NLO), biological evaluation, and ADME investigation	7
Oxidative cross dehydrogenative coupling directed carbamates synthesis using Cu(II) pincer complex as active catalyst under mild reaction condition	7
Efficient synthesis and biological evaluation of some new series of pyridine derivatives: Promising and potent new class of anticancer agents	7
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Design, Synthesis of Novel Pyrimidine Derivatives Containing Alkenyl Moieties With Herbicidal Activities	7
Synthesis, Photophysical Properties and Cytotoxic Activities of Isoxazole‐Containing Difluoroboron Complexes	7
Ultrasound promoted three‐component synthesis of dihydroindeno[1,2‐b]pyrrole derivatives	7
Green Construction of Novel 3‐(Benzo[d][1,3]dioxol‐5‐yl)‐1,8‐naphthyridin‐2‐yl)amino)quinazoline‐2,4(1H,3H)‐dione and Phenyl‐[1,2,4]triazolo[4,3‐a][1,8]naphthyridine and Their An	7
Formation of anti‐Bredt‐type azabicyclo[4.2.0]octene frameworks through photochemical intramolecular [2+2] cycloaddition between indole and a distal double bond of allene	7
Issue Information	7
Ni‐Ferrite an efficient catalyst for synthesis of 3‐aryl substituted isoxazole‐5‐carboxylic acids via one‐pot multicomponent reaction	7
Recent developments in synthetic strategies and pharmacological outcomes of synthetic xanthine oxidase inhibitors: A comprehensive review	7
Issue Information	7
A simple and efficient approach for the clickability of super‐bulky aryl azides	7
Study on halogen promoted cyclization of 2‐alkynylthiobenzimidazoles	7
Medicinal perspective of quinazolinone derivatives: Recent developments and structure–activity relationship studies	7
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Novel oxadiazole functionalized pyridopyrimidine derivatives; their anticancer activity and molecular docking studies	6
Hantzsch‐like reaction of isoquinoline‐1‐acetonitrile in synthesis of 4H‐pyrido[2,1‐a]isoquinolines with antibacterial evaluation	6
Regioselective synthesis and computational calculation studies of some new pyrazolyl‐pyridine and bipyridine derivatives	6
Regioselective synthesis of fused pyrimidines and quinazolines linked to Phenoxy‐N‐arylacetamide moieties as novel hybrid molecules via Biginelli‐like reaction	6
Synthesis and Cancer Cell Cytotoxicity of 6‐, 7‐, or 8‐Substituted 2‐(Hetero)aryl‐4‐(4‐(Hetero)aryl‐2‐Oxobut‐3‐en‐1‐Ylidene)Benzothiazepanes	6
Synthesis, antiinflammatory, and cytotoxic activity of novel pyrazolo[4,3‐c][2,1]benzothiazine 4,4‐dioxide derivatives	6
Recent Advances in the Chemistry of Selenopheno[2,3‐b &3,4‐b&3,4‐c]selenophenes and Their Analogues	6
Synthesis and anticancer activity of cinnoline sulphonamides and 4‐heteroyclic derivatives: Cross‐coupling approach	6
Synthesis and biological evaluation of 3‐hydroxypyrazoles as aquaporin 9 inhibitors	6
Design, synthesis, and biological evaluation of 1,4,7,8‐tetrahydro‐5H‐furo[3,4‐b]pyrazolo[4,3‐e]pyridin‐5‐one‐based azo dyes	6
BimetallicCoCeO2oxide nanoparticles: An efficient and reusable heterogeneous catalyst for the preparation of2‐amino‐3‐cyano‐4H‐pyran derivatives	6
Synthesis of various functionalized 2H‐azirines: An updated library	6
Highly efficient microwave‐assisted solvent free sequential one‐pot multicomponent synthesis of novel 2‐hydroxy indenopyridin‐5‐ones and mechanismic computational study	6
Design, Synthesis, and Structure–Activity Relationship of Some New Ciprofloxacin Hybrids as Antibacterial Agents	6
A Green Approach for the Synthesis of 5,6‐Dihydropyrimido[4,5‐d]Pyrimidines From N‐Uracil Amidines in Water	6
Design, synthesis, antifungal activity, and molecular docking of novel trifluoromethyl pyrimidine derivatives containing 1,3,4‐oxadiazole and thioether moieties as potential succinate dehyd	6
Issue Information	6
Study on antitumor activity of parthenolide C‐14 derivatives	6
Green multicomponent approach to novel 5‐[(2H‐Pyran‐3‐yl)(aryl)methyl]‐1,3‐dimethylpyrimidines	6
A search for antiinflammatory therapies: Synthesis, in silico investigation of the mode of action, and in vitro analyses of new quinazolin‐2,4‐dione derivatives targeting phosphodiesterase‐4 enzyme	6
Retraction statement: Design and synthesis of a bismethylsulfanyl‐steroid‐azetyl butanol derivative from 2‐nitroestradiol	6
The synthesis of novel 2, 3‐disubstituted 1,6‐dihydropyrrolo[2,3‐g]indazole derivatives via one‐pot three component reactions	6
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A Comprehensive Report on Environmentally Benign Synthesis of 1, 8‐Dioxo‐Octahydroxanthene Derivatives	6
Pyranoquinolone derivatives: A potent multi‐targeted pharmacological scaffold	6
Catalyst‐free one‐pot synthesis of quinoline tethered α‐amino ketones by multicomponent reactions	6
Base promoted CuFe2O4 catalyzed one‐pot synthesis of 3,5‐diaryl‐1H‐pyrazoles	6
An efficient synthesis of 4,6‐diarylnicotinonitrile‐acetamide hybrids via 1,2,3‐triazole linker as multitarget microbial inhibitors	6
N‐Methoxy Pyrazole‐4‐Carboxamide Derivatives: Synthesis, Spectral Analyses, Antifungal Activity, In Silico Molecular Docking, ADMET, and DFT Studies	6
Synthesis and anticancer activity of some thiophene, thienyl‐thiazole, and thienyl‐benzofuran analogues	6
A review on advances in synthetic methodology and biological profile of spirothiazolidin‐4‐ones	6
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A selective chromone‐based colorimetric chemosensor for detecting Cu2+ in near‐perfect aqueous solution and test kit	6
Synthesis and antiviral activity of novel imidazo[2,1‐b]thiazoles coupled with morpholine and thiomorpholines	6
Preparation of chiral DMAP derivatives and investigation on their enantioselective catalytic activity in benzazetidine synthesis and kinetic resolutions of alcohols	5
Issue Information	5
(±)‐cis‐4a‐alkyl‐1,3,4,4a,9,9a‐hexahydro‐2H‐carbazol‐2‐ones by domino nitro reduction‐aza‐Michael addition to enones	5
New thieno[2,3‐d]pyrimidine derivatives as EGFRWT and EGFRT790M inhibitors: Design, synthesis, antiproliferative activities, docking studi	5
Synthesis, characterization, and photophysical properties of some new thieno[2,3‐b]pyridines bearing phenylethenyl moiety	5
Issue Information	5
A Solvent‐Free One‐Pot Synthesis of Ethyl 4‐Oxo‐3,4‐Dihydro Quinazoline‐2‐Carboxylates Utilizing N‐(2‐Aminobenzoyl) Benzotriazoles	5
Synthesis, crystal structure, and DFT study of 4‐(2‐Chlorobenzyl)‐1‐(furan‐2‐yl)‐[1,2,4]triazolo[4,3‐a]quinazolin‐5(4H)‐one	5
Baylis–Hillmanadducts as an important synthon for the synthesis of α‐carbolinone and α‐carboline derivatives	5
Antimicrobial and antiproliferative study of chalcone clubbed 2,4‐dimethylpyrrole‐3‐carboxamide derivatives: Synthesis and in vitro evaluation	5
Practical synthesis of (S)‐pyroglutamic acid	5
A convenient and efficient process for the synthesis of 9‐aryl‐6,9‐dihydro‐1H‐pyrazolo[3,4‐f] quinoline‐8‐carbonitrile and 1‐aryl‐1,4‐ dihydrobenzo[f]quinoline‐2‐carbon	5
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Synthesis, physico‐chemical characterization and theoretical exploration of some 2,4,5‐triaryl imidazole derivatives	5
Synthetic, spectroscopic, and computational investigations of readily accessible 2‐phenyl‐3‐alkylbenzoxazaboroles	5
Issue Information	5
Chemoselective direct amidation of fatty acids with furfurylamine without coupling reagents in reversed micellar microenvironment	5
Discovery of novel heterocyclic derivatives containing oxadiazolone or pyrimidinone cores as DPP‐4 inhibitors	5
One‐Pot, Multicomponent Synthesis of 1,3‐Oxazin‐One and Evaluation of Their Potential Antioxidant Activities	5
Oriented synthesis and insecticidal activities of novel meta‐diamide scaffolds incorporating with 1,2,4‐triazole moiety	5
New oxadiazol‐5‐ones derivatives and their performance as angiotensin‐converting enzyme (ACE) inhibitors	5
Design, enantioselective synthesis, and antiviral activities against potato virus Y of axially chiral thiazine derivatives	5
Unusual impurity formation during the process development of Olsalazine sodium leads to a new efficient and economical synthesis of tricaine mesylate	5
Green synthesis and biological activity investigation of new derivatives of spiroisatins	5
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Synthesis, anticancer evaluation and in silico studies of novel N‐substituted arylidenethiazolidine‐2,4‐dione derivatives as adenosine monophosphate‐activated protein kinase activators	5
Organocatalytic Enantioselective Synthesis of Oxindole‐4‐Aminopyrazolone Derivatives via Mannich Reaction of 3‐Substituted Oxindoles With Pyrazolinone Ketimines	5
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A high‐yielding protocol for the synthesis of 4,5‐diarylpyrimidin‐2‐amine derivatives from chalcones	5
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2‐Vinylaniline in the synthesis of heterocycles: Recent advances	5
β‐Nitrostyrenes as a valuable precursor for the synthesis of β‐aryl‐γ‐lactam and 2‐oxo‐1,2‐dihydroquinoline derivatives	5
Substrate‐controlled chemoselective synthesis of 1‐sulfonylquinazoline‐2,4(1H,3H)‐diones and 2‐sulfonamidobenzonitriles	5
An eco‐efficient new path of mortar pestle grinding approach for the construction of methanol and ethylthio substituted pyridines with in silico studies	5
Pyrazolo[3,4‐d]pyrimidine‐based scaffolds as antibacterial agents: Synthetic strategies, reactions, and in vitro biological evaluation	5