Journal of Lipid Research

Article	Citations
Plasma S1P and Sphingosine are not Different Prior to Pre-Eclampsia in Women at High Risk of Developing the Disease	152
Bioorthogonal azido-S1P works as substrate for S1PR1	95
Specific approaches and limitations in (multi)-omic Mendelian randomization	63
A simplified method for preventing postmortem alterations of brain prostanoids for true in situ level quantification	53
Cardiomyopathy in a c.1528G>C Hadha mouse is associated with cardiac tissue lipotoxicity and altered cardiolipin species	52
The role of lysosomal phospholipase A2 in the catabolism of bis(monoacylglycerol)phosphate and association with phospholipidosis	51
Elevation of hepatic de novo lipogenesis in mice with overnutrition is dependent on multiple substrates	47
TMEM241 is a UDP-N-acetylglucosamine transporter required for M6P modification of NPC2 and cholesterol transport	43
Four-dimensional lipidomics profiling in X-linked adrenoleukodystrophy using trapped ion mobility mass spectrometry	39
A comprehensive measure of Golgi sphingolipid flux using NBD C6-ceramide: evaluation of sphingolipid inhibitors	39
Nuclear lipid droplets in Caco2 cells originate from nascent precursors and in situ at the nuclear envelope	38
Development of a novel spatiotemporal depletion system for cellular cholesterol	37
Measuring Lp(a) particles with a novel isoform-insensitive immunoassay illustrates efficacy of muvalaplin	32
Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein	32
Dietary docosahexaenoic acid (DHA) downregulates liver DHA synthesis by inhibiting eicosapentaenoic acid elongation	28
Altered hepatic lipid droplet morphology and lipid metabolism in fasted Plin2-null mice	28
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In memoriam: Ana Jonas, PhD	24
Lipidomics and mass spectrometry imaging unveil alterations in mice hippocampus lipid composition exposed to hypoxia	24
Effects of exercise training on ANGPTL3/8 and ANGPTL4/8 and their associations with cardiometabolic traits	23
Creation of a novel zebrafish model with low DHA status to study the role of maternal nutrition during neurodevelopment	22
The role of high-density lipoproteins in sepsis	22
ABHD4 regulates adipocyte differentiation in vitro but does not affect adipose tissue lipid metabolism in mice	22
Choline kinase inhibition promotes ER-phagy	21

Hepatocytes Deficient in Nuclear Envelope Protein Lamina-associated Polypeptide 1 are an Ideal Mammalian System to Study Intranuclear Lipid Droplets	21
A fluorogenic substrate for the detection of lipid amidases in intact cells	20
Introduction of a Lipidomics Scoring System for data quality assessment	19
The adipocyte apolipoprotein M is negatively associated with inflammation	19
KIAA1363 affects retinyl ester turnover in cultured murine and human hepatic stellate cells	19
Brown adipose tissue facilitates the fever response following infection with Salmonella enterica serovar Typhimurium in mice	19
Dietary modulation of Lp(a): more questions than answers	19
Effect of IL-6R blockade on plasma lipids and clinical outcomes among hospitalized patients with COVID-19 infection	18
Development and application of an LC-MS/MS method for the combined quantification of oxysterols and bile acids	18
Hepatic Deletion of X-Box Binding Protein 1 in FXR Null Mice Leads to Enhanced Liver Injury	18
Deep-lipidotyping by mass spectrometry: recent technical advances and applications	18
Eicosapentaenoic Acid Ameliorates Cardiac Fibrosis and Tissue Inflammation in Spontaneously Hypertensive Rats	18
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The one-key-to-two-doors role of lipidomics: plasma lipidome, cardiovascular risk and statin usage	18
TLR4 in POMC neurons regulates thermogenesis in a sex-dependent manner	17
Corrigendum to Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway	17
Efficacy of a novel PCSK9 inhibitory peptide alone and with evinacumab in a mouse model of atherosclerosis	17
The role of N-terminal phosphorylation of DGK-θ	16
DFCP1 is a regulator of starvation-driven ATGL-mediated lipid droplet lipolysis	16
Metabolic switch from glycogen to lipid in the liver maintains glucose homeostasis in neonatal mice	16
Dissecting cell type–specific impact in lysosomal acid lipase deficiency–associated disorders	15
Saroglitazar is noninferior to fenofibrate in reducing triglyceride levels in hypertriglyceridemic patients in a randomized clinical trial	15
Elevated high-density lipoprotein triglycerides increase atherosclerotic risk	15
Detergent-induced quantitatively limited formation of diacyl phosphatidylinositol dimannoside in Mycobacterium smegmatis	15
Diet-induced obesity dampens the temporal oscillation of hepatic mitochondrial lipids	15
Characterizing genetic profiles for high triglyceride levels in U.S. patients of African ancestry	15
2-Hydroxypropyl-β-cyclodextrin mitigates pathological changes in a mouse model of retinal cholesterol dyshomeostasis	15
Highly tail-asymmetric lipids interdigitate and cause bidirectional ordering	15
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Phosphatidic Acid Mediates the Nem1-Spo7/Pah1 Phosphatase Cascade in Yeast Lipid Synthesis	14
Mice deficient in ER protein seipin have reduced adrenal cholesteryl ester lipid droplet formation and utilization	14
Fatty acid nitroalkenes regulate intestinal lipid absorption	14
A facile assay for zDHHC palmitoyl transferase activation elucidates effects of mutation and modification	14
Elevated n-3/n-6 PUFA ratio in early life diet reverses adverse intrauterine kidney programming in female rats	14
Glucosylceramide flippases contribute to cellular glucosylceramide homeostasis	14
In Memoriam: Jan B Sjövall, MD, PhD, (1928–2024)	14
Lipidomic analysis of Porphyromonas gingivalis reveals novel glycerol bisphosphoceramide, phosphatidyl-, and phosphoglycerol dipeptide lipid families	14
Heptanol-mediated phase separation determines phase preference of molecules in live cell membranes	14
Polyunsaturated fatty acids stimulate immunity and eicosanoid production in Drosophila melanogaster	14
Spatial lipidomics of coronary atherosclerotic plaque development in a familial hypercholesterolemia swine model	13
Associations between serum cholesterol and immunophenotypical characteristics of circulatory B cells and Tregs	13
Tripartite motif 38 alleviates the pathological process of NAFLD–NASH by promoting TAB2 degradation	13
Association of plasma ceramide with decline in kidney function in patients with type 2 diabetes	13
Repurposing daclatasvir for MASLD Therapy—A promising step forward with challenges ahead	13
Circadian PER1 controls daily fat absorption with the regulation of PER1-PKA on phosphorylation of bile acid synthetase	13
High-density lipoproteins mediate small RNA intercellular communication between dendritic cells and macrophages	13
Cardiolipin remodeling maintains the inner mitochondrial membrane in cells with saturated lipidomes	13
Phosphatidylserine-decorated delivery platform helps alleviate acute lung injury via potentiating macrophage targeting	13
Apolipoprotein A1 and high-density lipoprotein limit low-density lipoprotein transcytosis by binding SR-B1	13
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Metallothionein 1B attenuates inflammation and hepatic steatosis in MASH by inhibiting the AKT/PI3K pathway	13
ORMDL mislocalization by impaired autophagy in Niemann-Pick type C disease leads to increased de novo sphingolipid biosynthesis	12
Participation of lipids in the tumor response to photodynamic therapy and its exploitation for therapeutic gain	12
Microbial products linked to steatohepatitis are reduced by deletion of nuclear hormone receptor SHP in mice	12
Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain	12
Consequences of excessive glucosylsphingosine in glucocerebrosidase-deficient zebrafish.	12
Intravital lipid droplet labeling and imaging reveals the phenotypes and functions of individual macrophages in vivo	12
Reducing saturated fat intake lowers LDL-C but increases Lp(a) levels in African Americans: the GET-READI feeding trial	12
Comprehensive mass spectrometry lipidomics of human biofluids and ocular tissues	12
Detecting white adipose tissue browning in mice with in vivo R2∗ mapping at 9.4T MRI	12
Dysregulation of mitochondrial dynamics and mitophagy are involved in high-fat diet-induced steroidogenesis inhibition	12
Decreased sarcoplasmic reticulum phospholipids in human skeletal muscle are associated with metabolic syndrome	12
HBV-miR-3 induces hepatic cholesterol accumulation by targeting ABCA1: evidence for potential benefits of statin usage	12
Liver proteomics identifies a disconnect between proteins associated with de novo lipogenesis and triglyceride storage	12
Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis	12
GCKIII kinases control hepatocellular lipid homeostasis via shared mode of action	12
Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice	11
Untargeted lipidomics reveals novel HDL metabotypes and lipid-clinical correlates	11
Hsp90α promotes lipogenesis by stabilizing FASN and promoting FASN transcription via LXRα in hepatocellular carcinoma	11
Substrate-dependent incorporation of 15-lipoxygenase products in glycerophospholipids: 15-HETE and 15-HEPE in PI, 17-HDHA in plasmalogen PE, and 13-HODE in PC	11
Comparison between genetic and pharmaceutical disruption of Ldlr expression for the development of atherosclerosis	11
Magnetic resonance imaging detects white adipose tissue beiging in mice following PDE10A inhibitor treatment	11
A multi-ancestry genome-wide association study and evaluation of polygenic scores of LDL-C levels	11
Quantitative characterizations of the cholesterol-related pathways in the retina and brain of hamsters	11
Measurement of 7-dehydrocholesterol and cholesterol in hair can be used in the diagnosis of Smith-Lemli-Opitz syndrome	11
Differential expression patterns of phospholipase D isoforms 1 and 2 in the mammalian brain and retina	11
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Hormone-sensitive lipase protects adipose triglyceride lipase-deficient mice from lethal lipotoxic cardiomyopathy	11
Strategies for consistent and automated quantification of HDL proteome using data-independent acquisition	11
Triglyceride-rich lipoprotein, remnant cholesterol, and apolipoproteins CII, CIII, and E in patients with schizophrenia	11
Causal association of blood lipids with all-cause and cause-specific mortality risk: a Mendelian randomization study	11
Alternative fatty acid desaturation pathways revealed by deep profiling of total fatty acids in RAW 264.7 cell line	11
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De(C1P)hering the role of ceramide-1-phosphate levels in skin wound healing	11
Unraveling the genetic background of individuals with a clinical familial hypercholesterolemia phenotype	11
Distinct pathways for the absorption and metabolism of β-carotene and zeaxanthin in the mouse intestine	11
Competitive displacement of lipoprotein lipase from heparan sulfate is orchestrated by a disordered acidic cluster in GPIHBP1	10
Targeting to high density lipoprotein cholesterol: new insights for inflammatory bowel disease treatment	10
Insulin dysregulation drives mitochondrial cholesterol metabolite accumulation: initiating hepatic toxicity in nonalcoholic fatty liver disease	10
Sorting through the extensive and confusing roles of sortilin in metabolic disease	10
Characteristic distribution of eicosapentaenoic acid in human abdominal aortic aneurysm wall	10
Adipose Tissue, Bile Acids, and Gut Microbiome Species Associated With Gallstones After Bariatric Surgery	10
Unbiased insights into the multiplicity of the CYP46A1 brain effects in 5XFAD mice treated with low dose-efavirenz	10
APOA5 deficiency causes hypertriglyceridemia by reducing amounts of lipoprotein lipase in capillaries	10
Blocking Lipid Uptake Pathways Does not Prevent Toxicity in Adipose Triglyceride Lipase (ATGL) Deficiency	10
Potential causal evidence for an ApoB-independent and HDL-related risk profile associated with coronary artery disease	10
Sphingomyelin is involved in regulating UCP1-mediated nonshivering thermogenesis	9
The Non Catalytic Protein ERG28 has a Functional Role in Cholesterol Synthesis and is Coregulated Transcriptionally	9
6-O-alkyl 4-methylumbelliferyl-β-D-glucosides as selective substrates for GBA1 in the discovery of glycosylated sterols	9
Ceramide kinase regulates acute wound healing by suppressing 5-oxo-ETE biosynthesis and signaling via its receptor OXER1	9
The lipidomics reporting checklist a framework for transparency of lipidomic experiments and repurposing resource data	9
Flavonoids regulate LDLR through different mechanisms tied to their specific structures	9
Pharmacological SERCA activation limits diet-induced steatohepatitis and restores liver metabolic function in mice	9
Decoding the role of angiopoietin-like protein 4/8 complex–mediated plasmin generation in the regulation of LPL activity	9
Effects of apolipoprotein H downregulation on lipid metabolism, fatty liver disease, and gut microbiota dysbiosis	9
Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder	9
Peridroplet mitochondria are associated with the severity of MASLD and the prevention of MASLD by diethyldithiocarbamate	9
Associations between insulin-like growth factor binding protein-2 and lipoprotein kinetics in men	9
Pioglitazone alleviates lacrimal gland impairments induced by high-fat diet by suppressing M1 polarization	9
Mining cholesterol genes from thousands of mouse livers identifies aldolase C as a regulator of cholesterol biosynthesis	9
Vascular lipid droplets formed in response to TNF, hypoxia, or OA: biochemical composition and prostacyclin generation	9
A historical, evidence-based, and narrative review on commonly used dietary supplements in lipid-lowering	9
Brown fat fuels the fire in fever	9
Global deletion of COX-2 attenuates hepatic inflammation but impairs metabolic homeostasis in diet-induced obesity	9
The SGLT2 inhibitor dapagliflozin promotes systemic FFA mobilization, enhances hepatic β-oxidation, and induces ketosis	9
The DNA methyltransferase inhibitor decitabine blunts the response to a high-animal fat and protein diet in mice	9
SDCCAG3 inhibits adipocyte hypertrophy and improves obesity-related metabolic disorders via SDCCAG3/SMURF1/PPARγ axis	9
Loss of Splicing Factor SRSF3 Impairs Lipophagy Through Ubiquitination and Degradation of Syntaxin17 in Hepatocytes	9
A high-cholesterol zebrafish diet promotes hypercholesterolemia and fasting-associated liver steatosis	9
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Human apoA-I[Lys107del] mutation affects lipid surface behavior of apoA-I and its ability to form large nascent HDL	8
A novel mutation, Ile344Asn, in microsomal triglyceride transfer protein abolishes binding to protein disulfide isomerase	8
Lipidomics of phospholipase A2 reveals exquisite specificity in macrophages	8
A targeted proteomics method for quantifying plasma apolipoprotein kinetics in individual mice using stable isotope labeling	8
LC-MS based simultaneous profiling of adrenal hormones of steroids, catecholamines, and metanephrines	8
2-fluoro-1-methylpyridinium p-toluene sulfonate: a new LC-MS/MS derivatization reagent for vitamin D metabolites	8
Unmasking crucial residues in adipose triglyceride lipase for coactivation with comparative gene identification-58	8
Potential causal and temporal relationship between plasma triglyceride levels and circulating leukocyte	8
A high-resolution 13C NMR approach for profiling fatty acid unsaturation in lipid extracts and in live Caenorhabditis elegans	8
Specific FAHFAs predict worsening glucose tolerance in non-diabetic relatives of people with Type 2 diabetes	8

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Relationship of apolipoprotein(a) isoform size with clearance and production of lipoprotein(a) in a diverse cohort	8
All-trans retinoic acid induces lipophagy by reducing Rubicon in Hepa1c1c7 cells	8
In Memoriam: G. Stephen (Steve) Tint, PhD (1935–2022)	8
Spatial lipidomics reveals zone-specific hepatic lipid alteration and remodeling in metabolic dysfunction-associated steatohepatitis	8
Hexokinase 2 promotes ISGylation of Acyl-CoA synthetase long-chain family member 4 in sepsis-induced microglia cells	8
The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases	8
Circulating membrane aminophospholipids contribute to thrombotic risk in rheumatoid arthritis	8
Does small HDL’s function improve when lipid-lowering alters its composition?	8
Determination of tissue contributions to the circulating lipid pool in cold exposure via systematic assessment of lipid profiles	8
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Sphingosine kinase 1 is involved in triglyceride breakdown by maintaining lysosomal integrity in brown adipocytes	8
Apolipoprotein F concentration, activity, and the properties of LDL controlling ApoF activation in hyperlipidemic plasma	8
Acute retinol mobilization by retinol-binding protein 4 in mouse liver induces fibroblast growth factor 21 expression	8
A basic model for the association of ligands with membrane cholesterol: application to cytolysin binding	8
Effect of type 2 diabetes on the inducible degrader of LDL receptor	7
Genetic deletion or pharmacologic inhibition of the Nlrp3 inflammasome did not ameliorate experimental NASH	7
Chronic cholesterol depletion increases F-actin levels and induces cytoskeletal reorganization via a dual mechanism	7
1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase	7
Maternal obesogenic diet enhances cholestatic liver disease in offspring	7
Correction: Unmasking crucial residues in adipose triglyceride lipase for coactivation with comparative gene identification-58	7
Toxoplasma acyl-CoA synthetase TgACS3 is crucial to channel host fatty acids in lipid droplets and for parasite propagation	7
Cholesteryl hemiazelate identified in CVD patients causes in vitro and in vivo inflammation	7
Unveiling the role of Mfsd2a and LPC-DHA in kidney repair	7
Elovl4b knockout zebrafish as a model for ocular very-long-chain PUFA deficiency	7
Inositol acylation of phosphatidylinositol mannosides: a rapid mass response to membrane fluidization in mycobacteria	7
Effects of coconut oil, olive oil, and butter on plasma fatty acids and metabolic risk factors: a randomized trial	7
Peroxisomal ether-glycerophospholipid synthesis is dysregulated after TBI	7
Ichthyosis linked to sphingosine 1-phosphate lyase insufficiency is due to aberrant sphingolipid and calcium regulation	7
ANGPTL4/8 promotes plasmin-mediated cleavage of LPL inhibitors	7
Changes in soluble LDL receptor and lipoprotein fractions in response to diet in the DIETFITS weight loss study	7
The sphingosine kinase 2 inhibitors ABC294640 and K145 elevate (dihydro)sphingosine 1-phosphate levels in various cells	7
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1-Deoxysphingolipid synthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells	6
Bioactive lipid mediators in plasma are predictors of preeclampsia irrespective of aspirin therapy	6
HDL meets triglyceride	6
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A sterol panel for rare lipid disorders: sitosterolemia, cerebrotendinous xanthomatosis and Smith-Lemli-Opitz syndrome	6
Resolvin D2/GPR 18 axis ameliorates pressure overload-induced heart failure by inhibiting pro-inflammatory macrophage polarization	6
Serum opacity factor normalizes erythrocyte morphology in Scarb1−/− mice in an HDL-free cholesterol-dependent way	6
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Helminth-induced prostaglandin signaling and dietary shifts in PUFA metabolism promote colitis-associated cancer	6
Integrated lipidomic and proteomic profiling reveals metabolic network disruption by SARS-CoV-2 variants	6
Loss of plasma membrane lipid asymmetry can induce ordered domain (raft) formation	6
Visualize neuronal membrane cholesterol with split-fluorescent protein tagged YDQA sensor	6
Analysis of omega-3 and omega-6 polyunsaturated fatty acid metabolism by compound-specific isotope analysis in humans	6
High Sensitivity and Wide Linearity LC-MS/MS Method for Oxylipin Quantification in Multiple Biological Samples	6
Pulmonary surfactant protein B carried by HDL predicts incident CVD in patients with type 1 diabetes	6
MUSTN1 and FABP3 interact to regulate adipogenesis and lipid deposition	6
Isomerization of bis(monoacylglycero)phosphate by acyl migration	6
Modification in mitochondrial function is associated with the FADS1 variant and its interaction with alpha-linolenic acid-enriched diet—An exploratory study	6
Conjugated bile acids are elevated in severe calcific aortic valve stenosis	6
Deducing formation routes of oxylipins by quantitative multiple heart-cutting achiral-chiral 2D-LC-MS	6
Whole picture of human stratum corneum ceramides, including the chain-length diversity of long-chain bases	6
Gly-β-MCA is a potent anti-cholestasis agent against “human-like” hydrophobic bile acid-induced biliary injury in mice	6
Sulfatide with ceramide composed of phytosphingosine (t18:0) and 2-hydroxy FAs in renal intercalated cells	6
Insights into the molecular changes of adipocyte dedifferentiation and its future research opportunities	6
Ceramide Analysis in Combination With Genetic Testing May Provide a Precise Diagnosis for Self-Healing Collodion Babies	6
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Apolipoprotein A1 deficiency increases macrophage apoptosis and necrotic core development in atherosclerotic plaques in a Bim-dependent manner	6
A fatty acid-ordered plasma membrane environment is critical for Ebola virus matrix protein assembly and budding	6
Modeling enzyme competition in eicosanoid metabolism in macrophage cells using a cybernetic framework	6
ASTER-B regulates mitochondrial carotenoid transport and homeostasis	6
Cholesterol sulfate fluidizes the sterol fraction of the stratum corneum lipid phase and increases its permeability	6
SCD4 deficiency decreases cardiac steatosis and prevents cardiac remodeling in mice fed a high-fat diet	5
Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues	5
Deletion of hepatic small heterodimer partner ameliorates development of nonalcoholic steatohepatitis in mice	5
Corrigendum: PCSK9 is not secreted from mature differentiated intestinal cells	5
Alterations in LDL and HDL after an ischemic stroke associated with carotid atherosclerosis are reversed after 1 year	5
Identification of plasma proteins binding oxidized phospholipids using pull-down proteomics and OxLDL masking assay	5
A high-throughput platform for the rapid screening of vitamin D status by direct infusion-MS/MS	5
Glycosylation of ceramide synthase 6 is required for its activity	5
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Type I IFN induces long-chain acyl-CoA synthetase 1 to generate a phosphatidic acid reservoir for lipotoxic saturated fatty acids	5
Uterine prostaglandin DP receptor-induced upon implantation contributes to decidualization together with EP4 receptor	5
Selective measurement of NAPE-PLD activity via a PLA1/2-resistant fluorogenic N-acyl-phosphatidylethanolamine analog	5
Phosphatidylthreonine is a procoagulant lipid detected in human blood and elevated in coronary artery disease	5
Identification of a Feed-Forward Loop Between 15(S)-HETE and PGE2 in Human Amnion at Parturition	5
Cholesterol affects the binding of proteins to phosphatidic acid without influencing its ionization properties	5
Stromal cell-derived NGF controls sympathetic innervation in subcutaneous fat	5
CD14loCD301b+ macrophages gathering as a proangiogenic marker in adipose tissues	5
Exogenous oxygen is required for prostanoid induction under brain ischemia as evidence for a novel regulatory mechanism	5
Oxidized phospholipids cause changes in jejunum mucus that induce dysbiosis and systemic inflammation	5
Dysregulated ceramide metabolism in mouse progressive dermatitis resulting from constitutive activation of Jak1	5
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ApoB100 remodeling and stiffened cholesteryl ester core raise LDL aggregation in familial hypercholesterolemia patients	4
Evaluation of antisense oligonucleotide therapy targeting Hsd17b13 in a fibrosis mice model	4
Cellular cholesterol loss by DHCR24 knockdown leads to Aβ production by changing APP intracellular localization	4
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Alveolar macrophage lipid burden correlates with clinical improvement in patients with pulmonary alveolar proteinosis	4
Identification of genetic drivers of plasma lipoprotein size in the Diversity Outbred mouse population	4
Development of a monoclonal antibody to study MARCH6, an E3 ligase that regulates proteins that control lipid homeostasis	4
Human hepatoma Huh-7 cell culture models deficient in apolipoprotein B secretion	4
Lipidomics reveals the reshaping of the mitochondrial phospholipid profile in cells lacking OPA1 and mitofusins	4
The reaction specificity of mammalian ALOX15B orthologs does not depend on the evolutionary ranking of the animals	4