Journal of Lipid Research

Article	Citations
A simplified method for preventing postmortem alterations of brain prostanoids for true in situ level quantification	142
Nuclear lipid droplets in Caco2 cells originate from nascent precursors and in situ at the nuclear envelope	80
Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein	57
Plasma S1P and Sphingosine are not Different Prior to Pre-Eclampsia in Women at High Risk of Developing the Disease	48
Bioorthogonal azido-S1P works as substrate for S1PR1	47
Specific approaches and limitations in (multi)-omic Mendelian randomization	46
Development of a novel spatiotemporal depletion system for cellular cholesterol	44
A comprehensive measure of Golgi sphingolipid flux using NBD C6-ceramide: evaluation of sphingolipid inhibitors	41
Measuring Lp(a) particles with a novel isoform-insensitive immunoassay illustrates efficacy of muvalaplin	36
Altered hepatic lipid droplet morphology and lipid metabolism in fasted Plin2-null mice	35
Dietary docosahexaenoic acid (DHA) downregulates liver DHA synthesis by inhibiting eicosapentaenoic acid elongation	35
Four-dimensional lipidomics profiling in X-linked adrenoleukodystrophy using trapped ion mobility mass spectrometry	34
Cardiomyopathy in a c.1528G>C Hadha mouse is associated with cardiac tissue lipotoxicity and altered cardiolipin species	31
The role of lysosomal phospholipase A2 in the catabolism of bis(monoacylglycerol)phosphate and association with phospholipidosis	29
TMEM241 is a UDP-N-acetylglucosamine transporter required for M6P modification of NPC2 and cholesterol transport	27
In memoriam: Ana Jonas, PhD	24
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Effect of IL-6R blockade on plasma lipids and clinical outcomes among hospitalized patients with COVID-19 infection	22
Effects of exercise training on ANGPTL3/8 and ANGPTL4/8 and their associations with cardiometabolic traits	21
KIAA1363 affects retinyl ester turnover in cultured murine and human hepatic stellate cells	21
Lipidomics and mass spectrometry imaging unveil alterations in mice hippocampus lipid composition exposed to hypoxia	21
The role of high-density lipoproteins in sepsis	21
Development and application of an LC-MS/MS method for the combined quantification of oxysterols and bile acids	20
Hepatocytes Deficient in Nuclear Envelope Protein Lamina-associated Polypeptide 1 are an Ideal Mammalian System to Study Intranuclear Lipid Droplets	20

Choline kinase inhibition promotes ER-phagy	20
The adipocyte apolipoprotein M is negatively associated with inflammation	19
Brown adipose tissue facilitates the fever response following infection with Salmonella enterica serovar Typhimurium in mice	19
A fluorogenic substrate for the detection of lipid amidases in intact cells	19
Dietary modulation of Lp(a): more questions than answers	19
Creation of a novel zebrafish model with low DHA status to study the role of maternal nutrition during neurodevelopment	17
Introduction of a Lipidomics Scoring System for data quality assessment	17
Eicosapentaenoic Acid Ameliorates Cardiac Fibrosis and Tissue Inflammation in Spontaneously Hypertensive Rats	16
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Deep-lipidotyping by mass spectrometry: recent technical advances and applications	16
ABHD4 regulates adipocyte differentiation in vitro but does not affect adipose tissue lipid metabolism in mice	16
The one-key-to-two-doors role of lipidomics: plasma lipidome, cardiovascular risk and statin usage	16
Efficacy of a novel PCSK9 inhibitory peptide alone and with evinacumab in a mouse model of atherosclerosis	15
The role of N-terminal phosphorylation of DGK-θ	15
Corrigendum to Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway	15
TLR4 in POMC neurons regulates thermogenesis in a sex-dependent manner	15
Hepatic Deletion of X-Box Binding Protein 1 in FXR Null Mice Leads to Enhanced Liver Injury	15
DFCP1 is a regulator of starvation-driven ATGL-mediated lipid droplet lipolysis	14
Saroglitazar is noninferior to fenofibrate in reducing triglyceride levels in hypertriglyceridemic patients in a randomized clinical trial	14
Dissecting cell type–specific impact in lysosomal acid lipase deficiency–associated disorders	14
Metabolic switch from glycogen to lipid in the liver maintains glucose homeostasis in neonatal mice	14
Detergent-induced quantitatively limited formation of diacyl phosphatidylinositol dimannoside in Mycobacterium smegmatis	14
Characterizing genetic profiles for high triglyceride levels in U.S. patients of African ancestry	14
In Memoriam: Jan B Sjövall, MD, PhD, (1928–2024)	14
Diet-induced obesity dampens the temporal oscillation of hepatic mitochondrial lipids	13
2-Hydroxypropyl-β-cyclodextrin mitigates pathological changes in a mouse model of retinal cholesterol dyshomeostasis	13
Heptanol-mediated phase separation determines phase preference of molecules in live cell membranes	13
Spatial lipidomics of coronary atherosclerotic plaque development in a familial hypercholesterolemia swine model	13
Associations between serum cholesterol and immunophenotypical characteristics of circulatory B cells and Tregs	13
Elevated high-density lipoprotein triglycerides increase atherosclerotic risk	13
Circadian PER1 controls daily fat absorption with the regulation of PER1-PKA on phosphorylation of bile acid synthetase	13
A facile assay for zDHHC palmitoyl transferase activation elucidates effects of mutation and modification	13
Lipidomic analysis of Porphyromonas gingivalis reveals novel glycerol bisphosphoceramide, phosphatidyl-, and phosphoglycerol dipeptide lipid families	13
Glucosylceramide flippases contribute to cellular glucosylceramide homeostasis	13
Polyunsaturated fatty acids stimulate immunity and eicosanoid production in Drosophila melanogaster	13
Highly tail-asymmetric lipids interdigitate and cause bidirectional ordering	13
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Elevated n-3/n-6 PUFA ratio in early life diet reverses adverse intrauterine kidney programming in female rats	13
Mice deficient in ER protein seipin have reduced adrenal cholesteryl ester lipid droplet formation and utilization	13
Phosphatidylserine-decorated delivery platform helps alleviate acute lung injury via potentiating macrophage targeting	12
Association of plasma ceramide with decline in kidney function in patients with type 2 diabetes	12
Consequences of excessive glucosylsphingosine in glucocerebrosidase-deficient zebrafish.	12
Cardiolipin remodeling maintains the inner mitochondrial membrane in cells with saturated lipidomes	12
Dysregulation of mitochondrial dynamics and mitophagy are involved in high-fat diet-induced steroidogenesis inhibition	12
Metallothionein 1B attenuates inflammation and hepatic steatosis in MASH by inhibiting the AKT/PI3K pathway	12
GCKIII kinases control hepatocellular lipid homeostasis via shared mode of action	12
ORMDL mislocalization by impaired autophagy in Niemann-Pick type C disease leads to increased de novo sphingolipid biosynthesis	12
Phosphatidic Acid Mediates the Nem1-Spo7/Pah1 Phosphatase Cascade in Yeast Lipid Synthesis	12
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Apolipoprotein A1 and high-density lipoprotein limit low-density lipoprotein transcytosis by binding SR-B1	12

Intravital lipid droplet labeling and imaging reveals the phenotypes and functions of individual macrophages in vivo	12
Reducing saturated fat intake lowers LDL-C but increases Lp(a) levels in African Americans: the GET-READI feeding trial	11
Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice	11
Alternative fatty acid desaturation pathways revealed by deep profiling of total fatty acids in RAW 264.7 cell line	11
High-density lipoproteins mediate small RNA intercellular communication between dendritic cells and macrophages	11
Measurement of 7-dehydrocholesterol and cholesterol in hair can be used in the diagnosis of Smith-Lemli-Opitz syndrome	11
Detecting white adipose tissue browning in mice with in vivo R2∗ mapping at 9.4T MRI	11
Quantitative characterizations of the cholesterol-related pathways in the retina and brain of hamsters	11
Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis	11
Liver proteomics identifies a disconnect between proteins associated with de novo lipogenesis and triglyceride storage	11
Participation of lipids in the tumor response to photodynamic therapy and its exploitation for therapeutic gain	11
Decreased sarcoplasmic reticulum phospholipids in human skeletal muscle are associated with metabolic syndrome	11
Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain	11
Causal association of blood lipids with all-cause and cause-specific mortality risk: a Mendelian randomization study	11
Microbial products linked to steatohepatitis are reduced by deletion of nuclear hormone receptor SHP in mice	11
Untargeted lipidomics reveals novel HDL metabotypes and lipid-clinical correlates	11
Comprehensive mass spectrometry lipidomics of human biofluids and ocular tissues	11
Tripartite motif 38 alleviates the pathological process of NAFLD–NASH by promoting TAB2 degradation	11
Hsp90α promotes lipogenesis by stabilizing FASN and promoting FASN transcription via LXRα in hepatocellular carcinoma	10
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Distinct pathways for the absorption and metabolism of β-carotene and zeaxanthin in the mouse intestine	10
Unraveling the genetic background of individuals with a clinical familial hypercholesterolemia phenotype	10
Competitive displacement of lipoprotein lipase from heparan sulfate is orchestrated by a disordered acidic cluster in GPIHBP1	10
Triglyceride-rich lipoprotein, remnant cholesterol, and apolipoproteins CII, CIII, and E in patients with schizophrenia	10
Strategies for consistent and automated quantification of HDL proteome using data-independent acquisition	10
A multi-ancestry genome-wide association study and evaluation of polygenic scores of LDL-C levels	10
Magnetic resonance imaging detects white adipose tissue beiging in mice following PDE10A inhibitor treatment	10
APOA5 deficiency causes hypertriglyceridemia by reducing amounts of lipoprotein lipase in capillaries	10
De(C1P)hering the role of ceramide-1-phosphate levels in skin wound healing	10
Hormone-sensitive lipase protects adipose triglyceride lipase-deficient mice from lethal lipotoxic cardiomyopathy	10
Differential expression patterns of phospholipase D isoforms 1 and 2 in the mammalian brain and retina	10
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Comparison between genetic and pharmaceutical disruption of Ldlr expression for the development of atherosclerosis	10
Sorting through the extensive and confusing roles of sortilin in metabolic disease	10
Ceramide kinase regulates acute wound healing by suppressing 5-oxo-ETE biosynthesis and signaling via its receptor OXER1	9
A high-cholesterol zebrafish diet promotes hypercholesterolemia and fasting-associated liver steatosis	9
Sphingomyelin is involved in regulating UCP1-mediated nonshivering thermogenesis	9
Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder	9
Potential causal evidence for an ApoB-independent and HDL-related risk profile associated with coronary artery disease	9
The lipidomics reporting checklist a framework for transparency of lipidomic experiments and repurposing resource data	9
Global deletion of COX-2 Attenuates Hepatic Inflammation but Impairs Metabolic Homeostasis in Diet-Induced Obesity	9
Unbiased insights into the multiplicity of the CYP46A1 brain effects in 5XFAD mice treated with low dose-efavirenz	9
Pioglitazone alleviates lacrimal gland impairments induced by high-fat diet by suppressing M1 polarization	9
The SGLT2 inhibitor dapagliflozin promotes systemic FFA mobilization, enhances hepatic β-oxidation, and induces ketosis	9
Adipose Tissue, Bile Acids, and Gut Microbiome Species Associated With Gallstones After Bariatric Surgery	9
Blocking Lipid Uptake Pathways Does not Prevent Toxicity in Adipose Triglyceride Lipase (ATGL) Deficiency	9
Brown fat fuels the fire in fever	9
The Non Catalytic Protein ERG28 has a Functional Role in Cholesterol Synthesis and is Coregulated Transcriptionally	9
Associations between insulin-like growth factor binding protein-2 and lipoprotein kinetics in men	9
Peridroplet mitochondria are associated with the severity of MASLD and the prevention of MASLD by diethyldithiocarbamate	9
Effects of apolipoprotein H downregulation on lipid metabolism, fatty liver disease, and gut microbiota dysbiosis	9
Insulin dysregulation drives mitochondrial cholesterol metabolite accumulation: initiating hepatic toxicity in nonalcoholic fatty liver disease	9
Characteristic distribution of eicosapentaenoic acid in human abdominal aortic aneurysm wall	9
6-O-alkyl 4-methylumbelliferyl-β-D-glucosides as selective substrates for GBA1 in the discovery of glycosylated sterols	9
Mining cholesterol genes from thousands of mouse livers identifies aldolase C as a regulator of cholesterol biosynthesis	8
Decoding the role of angiopoietin-like protein 4/8 complex–mediated plasmin generation in the regulation of LPL activity	8
Loss of Splicing Factor SRSF3 Impairs Lipophagy Through Ubiquitination and Degradation of Syntaxin17 in Hepatocytes	8
In Memoriam: G. Stephen (Steve) Tint, PhD (1935–2022)	8
A novel mutation, Ile344Asn, in microsomal triglyceride transfer protein abolishes binding to protein disulfide isomerase	8
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Specific FAHFAs Predict Worsening Glucose Tolerance in Non-Diabetic Relatives of People with Type 2 Diabetes	8
SDCCAG3 inhibits adipocyte hypertrophy and improves obesity-related metabolic disorders via SDCCAG3/SMURF1/PPARγ axis	8
Flavonoids regulate LDLR through different mechanisms tied to their specific structures	8
Pharmacological SERCA activation limits diet-induced steatohepatitis and restores liver metabolic function in mice	8
A targeted proteomics method for quantifying plasma apolipoprotein kinetics in individual mice using stable isotope labeling	8
All-trans retinoic acid induces lipophagy by reducing Rubicon in Hepa1c1c7 cells	8
Relationship of apolipoprotein(a) isoform size with clearance and production of lipoprotein(a) in a diverse cohort	8
Vascular lipid droplets formed in response to TNF, hypoxia, or OA: biochemical composition and prostacyclin generation	8
A historical, evidence-based, and narrative review on commonly used dietary supplements in lipid-lowering	8
The DNA methyltransferase inhibitor decitabine blunts the response to a high-animal fat and protein diet in mice	8
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Sphingosine kinase 1 is involved in triglyceride breakdown by maintaining lysosomal integrity in brown adipocytes	8
Apolipoprotein F concentration, activity, and the properties of LDL controlling ApoF activation in hyperlipidemic plasma	8
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Elovl4b knockout zebrafish as a model for ocular very-long-chain PUFA deficiency	7
Determination of tissue contributions to the circulating lipid pool in cold exposure via systematic assessment of lipid profiles	7
2-fluoro-1-methylpyridinium p-toluene sulfonate: a new LC-MS/MS derivatization reagent for vitamin D metabolites	7
Unmasking crucial residues in adipose triglyceride lipase for coactivation with comparative gene identification-58	7
A high-resolution 13C NMR approach for profiling fatty acid unsaturation in lipid extracts and in live Caenorhabditis elegans	7
Hexokinase 2 promotes ISGylation of Acyl-CoA synthetase long-chain family member 4 in sepsis-induced microglia cells	7

Potential causal and temporal relationship between plasma triglyceride levels and circulating leukocyte	7
A basic model for the association of ligands with membrane cholesterol: application to cytolysin binding	7
LC-MS based simultaneous profiling of adrenal hormones of steroids, catecholamines, and metanephrines	7
Lipidomics of phospholipase A2 reveals exquisite specificity in macrophages	7
Acute retinol mobilization by retinol-binding protein 4 in mouse liver induces fibroblast growth factor 21 expression	7
The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases	7
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Inositol acylation of phosphatidylinositol mannosides: a rapid mass response to membrane fluidization in mycobacteria	7
The sphingosine kinase 2 inhibitors ABC294640 and K145 elevate (dihydro)sphingosine 1-phosphate levels in various cells	7
Changes in soluble LDL receptor and lipoprotein fractions in response to diet in the DIETFITS weight loss study	7
Human apoA-I[Lys107del] mutation affects lipid surface behavior of apoA-I and its ability to form large nascent HDL	7
Spatial lipidomics reveals zone-specific hepatic lipid alteration and remodeling in metabolic dysfunction-associated steatohepatitis	7
Does small HDL’s function improve when lipid-lowering alters its composition?	7
1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase	7
Maternal obesogenic diet enhances cholestatic liver disease in offspring	7
1-Deoxysphingolipid synthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells	6
HDL meets triglyceride	6
Insights into the molecular changes of adipocyte dedifferentiation and its future research opportunities	6
ASTER-B regulates mitochondrial carotenoid transport and homeostasis	6
Genetic deletion or pharmacologic inhibition of the Nlrp3 inflammasome did not ameliorate experimental NASH	6
Effects of coconut oil, olive oil, and butter on plasma fatty acids and metabolic risk factors: a randomized trial	6
Correction: Unmasking crucial residues in adipose triglyceride lipase for coactivation with comparative gene identification-58	6
Cholesteryl hemiazelate identified in CVD patients causes in vitro and in vivo inflammation	6
Gly-β-MCA is a potent anti-cholestasis agent against “human-like” hydrophobic bile acid-induced biliary injury in mice	6
Peroxisomal ether-glycerophospholipid synthesis is dysregulated after TBI.	6
Visualize neuronal membrane cholesterol with split-fluorescent protein tagged YDQA sensor	6
Loss of plasma membrane lipid asymmetry can induce ordered domain (raft) formation	6
Ichthyosis linked to sphingosine 1-phosphate lyase insufficiency is due to aberrant sphingolipid and calcium regulation	6
Bioactive lipid mediators in plasma are predictors of preeclampsia irrespective of aspirin therapy	6
Chronic cholesterol depletion increases F-actin levels and induces cytoskeletal reorganization via a dual mechanism	6
Analysis of omega-3 and omega-6 polyunsaturated fatty acid metabolism by compound-specific isotope analysis in humans	6
Sulfatide with ceramide composed of phytosphingosine (t18:0) and 2-hydroxy FAs in renal intercalated cells	6
Cholesterol sulfate fluidizes the sterol fraction of the stratum corneum lipid phase and increases its permeability	6
Whole picture of human stratum corneum ceramides, including the chain-length diversity of long-chain bases	6
Unveiling the role of Mfsd2a and LPC-DHA in kidney repair	6
Deducing formation routes of oxylipins by quantitative multiple heart-cutting achiral-chiral 2D-LC-MS	6
Effect of type 2 diabetes on the inducible degrader of LDL receptor	6
Toxoplasma acyl-CoA synthetase TgACS3 is crucial to channel host fatty acids in lipid droplets and for parasite propagation	6
ANGPTL4/8 promotes plasmin-mediated cleavage of LPL inhibitors	6
High Sensitivity and Wide Linearity LC-MS/MS Method for Oxylipin Quantification in Multiple Biological Samples	6
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Ceramide Analysis in Combination With Genetic Testing May Provide a Precise Diagnosis for Self-Healing Collodion Babies	5
Resolvin D2/GPR 18 axis ameliorates pressure overload-induced heart failure by inhibiting pro-inflammatory macrophage polarization	5
Isomerization of bis(monoacylglycero)phosphate by acyl migration	5
Uterine prostaglandin DP receptor-induced upon implantation contributes to decidualization together with EP4 receptor	5
Serum opacity factor normalizes erythrocyte morphology in Scarb1−/− mice in an HDL-free cholesterol-dependent way	5
Cholesterol affects the binding of proteins to phosphatidic acid without influencing its ionization properties	5
Modeling enzyme competition in eicosanoid metabolism in macrophage cells using a cybernetic framework	5
A sterol panel for rare lipid disorders: sitosterolemia, cerebrotendinous xanthomatosis and Smith-Lemli-Opitz syndrome	5
Conjugated bile acids are elevated in severe calcific aortic valve stenosis	5
Apolipoprotein A1 deficiency increases macrophage apoptosis and necrotic core development in atherosclerotic plaques in a Bim-dependent manner	5
CD14loCD301b+ macrophages gathering as a proangiogenic marker in adipose tissues	5
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Modification in mitochondrial function is associated with the FADS1 variant and its interaction with alpha-linolenic acid-enriched diet—An exploratory study	5
A fatty acid-ordered plasma membrane environment is critical for Ebola virus matrix protein assembly and budding	5
MUSTN1 and FABP3 interact to regulate adipogenesis and lipid deposition	5
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Pulmonary surfactant protein B carried by HDL predicts incident CVD in patients with type 1 diabetes	5
Identification of plasma proteins binding oxidized phospholipids using pull-down proteomics and OxLDL masking assay	4
Glycosylation of ceramide synthase 6 is required for its activity	4
Deletion of hepatic small heterodimer partner ameliorates development of nonalcoholic steatohepatitis in mice	4
Selective measurement of NAPE-PLD activity via a PLA1/2-resistant fluorogenic N-acyl-phosphatidylethanolamine analog	4
Foamy monocytes and atherogenesis in mice with combined hyperlipidemia and effects of antisense knockdown of apoCIII	4
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Wide-scope targeted analysis of bioactive lipids in human plasma by LC/MS/MS	4
Multilayer regulation of postprandial triglyceride metabolism in response to acute cold exposure	4
Temporal dissociation of COX-2-dependent arachidonic acid and 2-arachidonoylglycerol metabolism in RAW264.7 macrophages	4
Dysregulated ceramide metabolism in mouse progressive dermatitis resulting from constitutive activation of Jak1	4
Exogenous oxygen is required for prostanoid induction under brain ischemia as evidence for a novel regulatory mechanism	4
Type I IFN induces long-chain acyl-CoA synthetase 1 to generate a phosphatidic acid reservoir for lipotoxic saturated fatty acids	4
Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues	4
Identification of a Feed-Forward Loop Between 15(S)-HETE and PGE2 in Human Amnion at Parturition	4
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Inflammatory markers after supplementation with marine n-3 or plant n-6 PUFAs: A randomized double-blind crossover study	4
Intestinal absorption of sphingosine: new insights on generated ceramide species using stable isotope tracing in vitro	4
The bile acid chenodeoxycholic acid associates with reduced stroke in humans and mice	4
10,12-Conjugated linoleic acid supplementation improves HDL composition and function in mice	4
Phosphatidylthreonine is a procoagulant lipid detected in human blood and elevated in coronary artery disease	4
Stromal cell-derived NGF controls sympathetic innervation in subcutaneous fat	4
A high-throughput platform for the rapid screening of vitamin D status by direct infusion-MS/MS	4
SCD4 deficiency decreases cardiac steatosis and prevents cardiac remodeling in mice fed a high-fat diet	4
Alterations in LDL and HDL after an ischemic stroke associated with carotid atherosclerosis are reversed after 1 year	4
Corrigendum: PCSK9 is not secreted from mature differentiated intestinal cells	4
Associations between plasma 24(S)-hydroxycholesterol and neuropsychological profile in fragile X syndrome	4
Targeting acetyl-CoA carboxylases for the treatment of MASLD	4
A single-day mouse mesenteric lymph surgery in mice: an updated approach to study dietary lipid absorption, chylomicron secretion, and lymphocyte dynamics	4
Antibodies against oxidation-specific epitopes and risk of acute myocardial infarction	4
Sphingolipid profiling reveals differential functions of sphingolipid biosynthesis isozymes of Caenorhabditis elegans	4
Oxidized phospholipids cause changes in jejunum mucus that induce dysbiosis and systemic inflammation	4
Lipid trajectories improve risk models for Alzheimer’s disease and mild cognitive impairment	3
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Deep sphingolipidomic and metabolomic analyses of ceramide synthase 2 null mice reveal complex pathway-specific effects	3
ω-O-Acylceramides but not ω-hydroxy ceramides are required for healthy lamellar phase architecture of skin barrier lipids	3
Evaluation of antisense oligonucleotide therapy targeting Hsd17b13 in a fibrosis mice model	3