Journal of Lipid Research

Article	Citations
Cover	126
Damage response protein 1 (Dap1) functions in the synthesis of carotenoids and sterols in Xanthophyllomyces dendrorhous	61
Staying sane in the membrane: Neutral sphingomyelinase 2 as a master regulator of plasma membrane ceramide	50
ANGPTL3 deficiency impairs lipoprotein production and produces adaptive changes in hepatic lipid metabolism	44
Elevated lipoprotein(a) as a predictor for coronary events in older men	43
Cholesterol trafficking to the ER leads to the activation of CaMKII/JNK/NLRP3 and promotes atherosclerosis	42
Small molecule-driven LKB1 deacetylation is responsible for the inhibition of hepatic lipid response in NAFLD	40
The small GTPase RAB10 regulates endosomal recycling of the LDL receptor and transferrin receptor in hepatocytes	37
A sterol panel for rare lipid disorders: sitosterolemia, cerebrotendinous xanthomatosis and Smith-Lemli-Opitz syndrome	35
Measuring Lp(a) particles with a novel isoform-insensitive immunoassay illustrates efficacy of muvalaplin	34
Cover	31
De(C1P)hering the role of ceramide-1-phosphate levels in skin wound healing	29
Magnetic resonance imaging detects white adipose tissue beiging in mice following PDE10A inhibitor treatment	28
Development of LC-FAIMS-MS and its application to lipidomics study of Acinetobacter baumannii infection	26
Four-dimensional lipidomics profiling in X-linked adrenoleukodystrophy using trapped ion mobility mass spectrometry	23
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Unraveling the genetic background of individuals with a clinical familial hypercholesterolemia phenotype	21
TMEM241 is a UDP-N-acetylglucosamine transporter required for M6P modification of NPC2 and cholesterol transport	20
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Is reverse cholesterol transport regulated by active cholesterol?	19
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Puncturing lipid membranes: onset of pore formation and the role of hydrogen bonding in the presence of flavonoids	18
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Resolvin D2/GPR 18 axis ameliorates pressure overload-induced heart failure by inhibiting pro-inflammatory macrophage polarization	17
High density lipoproteins and COVID-19: preparing the next pandemic	17

Prophages divert Staphylococcus aureus defenses against host lipids	17
Modeling enzyme competition in eicosanoid metabolism in macrophage cells using a cybernetic framework	16
Quantifying acyl-chain diversity in isobaric compound lipids containing monomethyl branched-chain fatty acids	16
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Strategies for consistent and automated quantification of HDL proteome using data-independent acquisition	15
Human HDL subclasses modulate energy metabolism in skeletal muscle cells	15
NanoSIMS imaging of lipid absorption by intestinal enterocytes	15
Apolipoprotein A1 deficiency increases Macrophage Apoptosis and Necrotic Core Development in Atherosclerotic Plaques in a Bim dependent manner	15
Characteristic fragmentation of polyunsaturated fatty acids with allylic vicinal diols in positive-ion LC/ESI-MS/MS	14
Nuclear lipid droplets in Caco2 cells originate from nascent precursors and in situ at the nuclear envelope	14
Loss of function and reduced levels of sphingolipid desaturase DEGS1 variants are both relevant in disease mechanism	14
A fatty acid-ordered plasma membrane environment is critical for Ebola virus matrix protein assembly and budding	13
Dietary modulation of lung lipids influences inflammatory responses to inhaled ozone	13
Effects of age and diet on triglyceride metabolism in mice	13
Effects of ketone bodies on energy expenditure, substrate utilization, and energy intake in humans	13
A comprehensive measure of Golgi sphingolipid flux using NBD C6-ceramide: evaluation of sphingolipid inhibitors	13
Mechanistic insights into metabolic function of dynamin-related protein 1	13
A simplified method for preventing postmortem alterations of brain prostanoids for true in situ level quantification	13
APOA5 deficiency causes hypertriglyceridemia by reducing amounts of lipoprotein lipase in capillaries	13
Hsp90α promotes lipogenesis by stabilizing FASN and promoting FASN transcription via LXRα in hepatocellular carcinoma	13
Inhibition of MAP4K4 signaling initiates metabolic reprogramming to protect hepatocytes from lipotoxic damage	12
Development of a novel spatiotemporal depletion system for cellular cholesterol	12
Lipoprotein(a), family history of cardiovascular disease, and incidence of heart failure	12
Bioorthogonal azido-S1P works as substrate for S1PR1	12
Differential expression patterns of phospholipase D isoforms 1 and 2 in the mammalian brain and retina	12
Skin fibroblast metabolomic profiling reveals that lipid dysfunction predicts the severity of Friedreich’s ataxia	12
HDL Isolated by Immunoaffinity, Ultracentrifugation, or Precipitation is Compositionally and Functionally Distinct	12
SREBP2 regulates the endothelial response to cytokines via direct transcriptional activation of KLF6	12
Pulmonary surfactant protein B carried by HDL predicts incident CVD in patients with type 1 diabetes	12
Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein	12
Direct anabolic metabolism of three-carbon propionate to a six-carbon metabolite occurs in vivo across tissues and species	12
Plasma S1P and Sphingosine are not Different Prior to Pre-Eclampsia in Women at High Risk of Developing the Disease	12
Lipid clearance and amyloid formation by serum amyloid A: exploring the links between beneficial and pathologic actions of an enigmatic protein	12
Development of oxaalkyne and alkyne fatty acids as novel tracers to study fatty acid beta-oxidation pathways and intermediates	12
Identification and characterization of 3-ketosphinganine reductase activity encoded at the BT_0972 locus in Bacteroides thetaiotaomicron	11
Serum opacity factor normalizes erythrocyte morphology in Scarb1−/− mice in an HDL-free cholesterol-dependent way	11
Sorting through the extensive and confusing roles of sortilin in metabolic disease	11
Setting the curve: the biophysical properties of lipids in mitochondrial form and function	11
Comparison between genetic and pharmaceutical disruption of Ldlr expression for the development of atherosclerosis	11
Specific approaches and limitations in (multi)-omic Mendelian randomization	11
LRP1 Immunotherapy Enhances Cardiomyocyte Respiration by Restricting Cholesteryl Ester Accumulation in Mitochondria	11
Clinical Lipidomics Reveals High Individuality and Sex Specificity of Circulatory Lipid Signatures: A Prospective Healthy Population Study	11
Novel insights into the modulation of the voltage-gated potassium channel KV1.3 activation gating by membrane ceramides	11
Modification in mitochondrial function is associated with the FADS1 variant and its interaction with alpha-linolenic acid-enriched diet—An exploratory study	11
The circadian clock is required for rhythmic lipid transport in Drosophila in interaction with diet and photic condition	11
Phosphatidylcholine synthesis and remodeling in brain endothelial cells	11
Distinct pathways for the absorption and metabolism of β-carotene and zeaxanthin in the mouse intestine	10
The SARS-CoV2 envelope differs from host cells, exposes procoagulant lipids, and is disrupted in vivo by oral rinses	10
Cholesterol affects the binding of proteins to phosphatidic acid without influencing its ionization properties	10
Dietary docosahexaenoic acid (DHA) downregulates liver DHA synthesis by inhibiting eicosapentaenoic acid elongation	10

A multi-ancestry genome-wide association study and evaluation of polygenic scores of LDL-C levels	10
Divergent effects of monomethyl branched-chain fatty acids on energy metabolism and insulin signaling in human myotubes	10
PI3KC2β depletion rescues endosomal trafficking defects in Mtm1 knockout skeletal muscle cells	10
Hormone-sensitive lipase protects adipose triglyceride lipase-deficient mice from lethal lipotoxic cardiomyopathy	10
Phosphoethanolamine cytidylyltransferase ameliorates mitochondrial function and apoptosis in hepatocytes in T2DM in vitro	10
Nuclear SphK2/S1P signaling is a key regulator of ApoE production and Aβ uptake in astrocytes	10
Isomerization of bis(monoacylglycero)phosphate by acyl migration	10
Apolipoprotein C3: form begets function	10
Ceramide Analysis in Combination With Genetic Testing May Provide a Precise Diagnosis for Self-Healing Collodion Babies	10
The role of lysosomal phospholipase A2 in the catabolism of bis(monoacylglycerol)phosphate and association with phospholipidosis	10
Dietary modulation of Lp(a): more questions than answers	9
Bacterial lipopolysaccharide forms aggregates with apolipoproteins in male and female rat brains after ethanol binges	9
Ceramide kinase regulates acute wound healing by suppressing 5-oxo-ETE biosynthesis and signaling via its receptor OXER1	9
Lipidomic and metabolomic changes in community-acquired and COVID-19 pneumonia	9
Altered hepatic lipid droplet morphology and lipid metabolism in fasted Plin2-null mice	9
Brown adipocyte mineralocorticoid receptor deficiency impairs metabolic regulation in diet-induced obese mice	9
Cardiomyopathy in a c.1528G>C Hadha Mouse is associated with Cardiac Tissue Lipotoxicity and Altered Cardiolipin Species	9
Metabolic changes and propensity for inflammation, fibrosis, and cancer in livers of mice lacking lysosomal acid lipase	9
Mfsd2a-mediated lysolipid transport is important for renal recovery after acute kidney injury	8
Blocking Lipid Uptake Pathways Does not Prevent Toxicity in Adipose Triglyceride Lipase (ATGL) Deficiency	8
MicroRNA-206 as a potential cholesterol-lowering drug is superior to statins in mice	8
In Memoriam: William L. Smith, PhD	8
CrrAB regulates PagP-mediated glycerophosphoglycerol palmitoylation in the outer membrane of Klebsiella pneumoniae	8
Highly flexible cell membranes are the key to efficient production of lipophilic compounds	8
Oxidized phospholipids cause changes in jejunum mucus that induce dysbiosis and systemic inflammation	8
Corrigendum to: [Activation of JNK/c-Jun is required for the proliferation, survival, and angiogenesis induced by EET in pulmonary artery endothelial cells]	8
In memoriam: Ana Jonas, PhD	8
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Enoyl-CoA hydratase/3-hydroxyacyl CoA dehydrogenase is essential for the production of DHA in zebrafish	8
Uterine prostaglandin DP receptor-induced upon implantation contributes to decidualization together with EP4 receptor	8
Phosphatidylthreonine is a procoagulant lipid detected in human blood and elevated in coronary artery disease	8
Loss of ABCA8B decreases myelination by reducing oligodendrocyte precursor cells in mice	7
Porcine transient receptor potential channel 1 promotes adipogenesis and lipid deposition	7
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Identification of two lipid phosphatases that regulate sphingosine-1-phosphate cellular uptake and recycling	7
A fluorogenic substrate for the detection of lipid amidases in intact cells	7
Histone demethylase KDM1A promotes hepatic steatosis and inflammation by increasing chromatin accessibility in NAFLD	7
Dalcetrapib and anacetrapib increase apolipoprotein E-containing HDL in rabbits and humans	7
The role of lipid second messengers in aldosterone synthesis and secretion	7
Type I IFN induces long-chain acyl-CoA synthetase 1 to generate a phosphatidic acid reservoir for lipotoxic saturated fatty acids	7
Natriuretic peptide receptor-C perturbs mitochondrial respiration in white adipose tissue	7
Glycosylation of ceramide synthase 6 is required for its activity	7
An Updated Perspective on the Dual-Track Model of Enterocyte Fat Metabolism	7
Sterol interactions influence the function of Wsc sensors	7
Dysregulated ceramide metabolism in mouse progressive dermatitis resulting from constitutive activation of Jak1	7
Exogenous oxygen is required for prostanoid induction under brain ischemia as evidence for a novel regulatory mechanism	7
Characteristic distribution of eicosapentaenoic acid in human abdominal aortic aneurysm wall	7
Lysophosphatidylethanolamine improves diastolic dysfunction by alleviating mitochondrial injury in the aging heart	7
Deep-lipidotyping by mass spectrometry: recent technical advances and applications	7
Choline kinase inhibition promotes ER-phagy	7
PI(4,5)P2 binding sites in the Ebola virus matrix protein VP40 modulate assembly and budding	7
Deletion of hepatic small heterodimer partner ameliorates development of nonalcoholic steatohepatitis in mice	7
Relationship between hepatic and mitochondrial ceramides: a novel in vivo method to track ceramide synthesis	7
siRNA nanoparticle targeting Usp20 lowers lipid levels and ameliorates metabolic syndrome in mice	6
Predictors of plasma HDL-C concentrations in the Coronary Artery Risk Development in Young Adults (CARDIA) study	6
Cover	6
Brown adipose tissue facilitates the fever response following infection with Salmonella enterica serovar Typhimurium in mice	6
Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues	6
A (cholesterol) crystal clear path to inflammasome activation in atherosclerosis	6
Creation of a novel zebrafish model with low DHA status to study the role of maternal nutrition during neurodevelopment	6
Novel eicosanoid signature in plasma provides diagnostic for metabolic dysfunction-associated steatotic liver disease	6
Hepatocytes Deficient in Nuclear Envelope Protein Lamina-associated Polypeptide 1 are an Ideal Mammalian System to Study Intranuclear Lipid Droplets	6
Fads2 knockout mice reveal that ALA prevention of hepatic steatosis is dependent on delta-6 desaturase activity	6
Matrix stiffness regulates the triad communication of adipocytes/macrophages/endothelial cells through CXCL13	6
SCD4 deficiency decreases cardiac steatosis and prevents cardiac remodeling in mice fed a high-fat diet	6
Effect of IL-6R blockade on plasma lipids and clinical outcomes among hospitalized patients with COVID-19 infection	6
FASN inhibitor TVB-3166 prevents S-acylation of the spike protein of human coronaviruses	6
Characterization of sexual dimorphism in ANGPTL4 levels and function	6
Effects of exercise training on ANGPTL3/8 and ANGPTL4/8 and their associations with cardiometabolic traits	6
The adipocyte apolipoprotein M is negatively associated with inflammation	6
Stromal cell-derived NGF controls sympathetic innervation in subcutaneous fat	5
Transgelin: a new gene involved in LDL endocytosis identified by a genome-wide CRISPR-Cas9 screen	5
A high-throughput platform for the rapid screening of vitamin D status by direct infusion-MS/MS	5
sEV-mediated lipid droplets transferred from bone marrow adipocytes promote ferroptosis and impair osteoblast function	5
Validation of a multiplexed and targeted lipidomics assay for accurate quantification of lipidomes	5
Eicosapentaenoic acid reduces the proportion of IL-17A–producing T cells in a 3D psoriatic skin model	5
6-O-alkyl 4-methylumbelliferyl-β-D-glucosides as selective substrates for GBA1 in the discovery of glycosylated sterols	5
Brown fat fuels the fire in fever	5
Elevated levels of serum alpha-2-macroglobulin associate with diabetes status and incident CVD in type 1 diabetes	5

The role of high-density lipoproteins in sepsis	5
Alterations in LDL and HDL after an ischemic stroke associated with carotid atherosclerosis are reversed after 1 year	5
Selective measurement of NAPE-PLD activity via a PLA1/2-resistant fluorogenic N-acyl-phosphatidylethanolamine analog	5
In memoriam: Judith A. Berliner, Ph.D.	5
The SGLT2 inhibitor dapagliflozin promotes systemic FFA mobilization, enhances hepatic β-oxidation, and induces ketosis	5
Peridroplet mitochondria are associated with the severity of MASLD and the prevention of MASLD by diethyldithiocarbamate	5
Identification of plasma proteins binding oxidized phospholipids using pull-down proteomics and OxLDL masking assay	5
Unbiased insights into the multiplicity of the CYP46A1 brain effects in 5XFAD mice treated with low dose-efavirenz	5
KIAA1363 affects retinyl ester turnover in cultured murine and human hepatic stellate cells	5
Adipose Tissue, Bile Acids, and Gut Microbiome Species Associated With Gallstones After Bariatric Surgery	5
Pitavastatin treatment remodels the HDL subclass lipidome and proteome in hypertriglyceridemia	5
Cover	5
Endogenous and fluorescent sterols reveal the molecular basis for ligand selectivity of human sterol transporters	5
Lysosphingolipids in ceramide-deficient skin lipid models	5
ABHD4 regulates adipocyte differentiation in vitro but does not affect adipose tissue lipid metabolism in mice	5
Gut microbiome-derived glycine lipids are diet-dependent modulators of hepatic injury and atherosclerosis	5
Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder	5
Targeted removal of the FA2 site on human albumin prevents fatty acid–mediated inhibition of Zn2+ binding	5
The Non Catalytic Protein ERG28 has a Functional Role in Cholesterol Synthesis and is Coregulated Transcriptionally	5
Development and application of an LC-MS/MS method for the combined quantification of oxysterols and bile acids	5
Identification of a Feed-Forward Loop Between 15(S)-HETE and PGE2 in Human Amnion at Parturition	5
LDL-C calculated by Friedewald, Martin-Hopkins, or NIH equation 2 versus beta-quantification: pooled alirocumab trials	5
Low LCAT activity is linked to acute decompensated heart failure and mortality in patients with CKD	5
Eicosapentaenoic Acid Ameliorates Cardiac Fibrosis and Tissue Inflammation in Spontaneously Hypertensive Rats	5
Etomoxir-carnitine, a novel pharmaco-metabolite of etomoxir, inhibits phospholipases A2 and mitochondrial respiration	5
CD14loCD301b+ macrophages gathering as a proangiogenic marker in adipose tissues	5
The importance of choosing the appropriate cholesterol quantification method: enzymatic assay versus gas chromatography	5
Ki-67 and CDK1 control the dynamic association of nuclear lipids with mitotic chromosomes	4
New epigenome players in the regulation of PCSK9-H3K4me3 and H3K9ac alterations by statin in hypercholesterolemia	4
Cadmium-cardiolipin disruption of respirasome assembly and redox balance through mitochondrial membrane rigidification	4
Imaging the ANGPTL3/8-mediated regulation of lipoprotein lipase in the heart	4
Neutral ceramidase deficiency protects against cisplatin-induced acute kidney injury	4
Regulation of astrocyte lipid metabolism and ApoE secretion by the microglial oxysterol, 25-hydroxycholesterol	4
Effects of apolipoprotein H downregulation on lipid metabolism, fatty liver disease, and gut microbiota dysbiosis	4
Intestinal absorption of sphingosine: new insights on generated ceramide species using stable isotope tracing in vitro	4
Exploring contrast-enhancing staining agents for studying adipose tissue through contrast-enhanced computed tomography	4
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HDL-free cholesterol influx into macrophages and transfer to LDL correlate with HDL-free cholesterol content	4
Zonal expression of StARD1 and oxidative stress in alcoholic-related liver disease	4
Lipidomics and mass spectrometry imaging unveil alterations in mice hippocampus lipid composition exposed to hypoxia	4
Insulin dysregulation drives mitochondrial cholesterol metabolite accumulation: initiating hepatic toxicity in nonalcoholic fatty liver disease	4
Liver-specific FGFR4 knockdown in mice on an HFD increases bile acid synthesis and improves hepatic steatosis	4
Competitive displacement of lipoprotein lipase from heparan sulfate is orchestrated by a disordered acidic cluster in GPIHBP1	4
Deleting adipose FXR exacerbates metabolic defects and induces endocannabinoid lipid, 2-oleoyl glycerol, in obesity	4
High-fat diet reveals the impact of Sar1b defects on lipid and lipoprotein profile and cholesterol metabolism	4
Serum dihydroceramides correlate with insulin sensitivity in humans and decrease insulin sensitivity in vitro	4
Clinical characterization and mutation spectrum of patients with hypertriglyceridemia in a German outpatient clinic	4
The bile acid chenodeoxycholic acid associates with reduced stroke in humans and mice	4
Spatial characterization of RPE structure and lipids in the PEX1-p.Gly844Asp mouse model for Zellweger spectrum disorder	4
The lipidomics reporting checklist a framework for transparency of lipidomic experiments and repurposing resource data	4
Rosiglitazone Reverses Inflammation in Epididymal White Adipose Tissue in Hormone-Sensitive Lipase-Knockout Mice	4
Potential causal evidence for an ApoB-independent and HDL-related risk profile associated with coronary artery disease	4
Finasteride delays atherosclerosis progression in mice and is associated with a reduction in plasma cholesterol in men	4
Striking membrane defects in AdipoR-deficient cells	4
ABCA1-mediated nascent HDL formation is precisely regulated by the plasma membrane cholesterol	4
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The fate of intracellular S1P regulates lipid droplet turnover and lipotoxicity in pancreatic beta-cells	3
Effect of omega-3 ethyl esters on the triglyceride-rich lipoprotein response to endotoxin challenge in healthy young men	3
DFCP1 is a regulator of starvation-driven ATGL-mediated lipid droplet lipolysis	3
Optical control of sphingolipid biosynthesis using photoswitchable sphingosines	3
Characterizing genetic profiles for high triglyceride levels in U.S. patients of African ancestry	3
TLR4 in POMC neurons regulates thermogenesis in a sex-dependent manner	3
Metabolic switch from glycogen to lipid in the liver maintains glucose homeostasis in neonatal mice	3
A validated HPLC-MS/MS method for the simultaneous determination of ecdysteroid hormones in subminimal amounts of biological material	3
Apolipoprotein B gene expression and regulation in relation to Alzheimer’s disease pathophysiology	3
Hypertriglyceridemic hyperapoB and the development and resolution of nonalcoholic fatty liver disease: a cohort study	3
Six-Transmembrane Epithelial Antigen of Prostate 3 Promotes Hepatic Insulin Resistance and Steatosis	3
Mining cholesterol genes from thousands of mouse livers identifies aldolase C as a regulator of cholesterol biosynthesis	3
Ola1p trafficking indicates an interaction network between mitochondria, lipid droplets, and stress granules in times of stress	3
A single-day mouse mesenteric lymph surgery in mice: an updated approach to study dietary lipid absorption, chylomicron secretion, and lymphocyte dynamics	3
ANGPTL8 deficiency attenuates lipopolysaccharide-induced liver injury by improving lipid metabolic dysregulation	3
10,12-Conjugated linoleic acid supplementation improves HDL composition and function in mice	3
Pioglitazone alleviates lacrimal gland impairments induced by high-fat diet by suppressing M1 polarization	3
A high-cholesterol zebrafish diet promotes hypercholesterolemia and fasting-associated liver steatosis	3
FASN negatively regulates p65 expression by reducing its stability via Thr254 phosphorylation and isomerization by Pin1	3
Antibodies against oxidation-specific epitopes and risk of acute myocardial infarction	3
Regulated translocation of neutral sphingomyelinase-2 to the plasma membrane drives insulin resistance in steatotic hepatocytes	3
Adipose-derived mesenchymal stem cells' adipogenesis chemistry analyzed by FTIR and Raman metrics	3
Sphingolipid profiling reveals differential functions of sphingolipid biosynthesis isozymes of Caenorhabditis elegans	3
Sphingomyelin is involved in regulating UCP1-mediated nonshivering thermogenesis	3
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High immunoglobulin-M levels to oxidation-specific epitopes are associated with lower risk of acute myocardial infarction	3
MicroRNA-615-3p decreases apo B expression in human liver cells	3
Associations between insulin-like growth factor binding protein-2 and lipoprotein kinetics in men	3
Targeting acetyl-CoA carboxylases for the treatment of MASLD	3
PCSK9 is minimally associated with HDL but impairs the anti-atherosclerotic HDL effects on endothelial cell activation	3
Pharmacological SERCA activation limits diet-induced steatohepatitis and restores liver metabolic function in mice	3
ELOVL4 Mutations That Cause Spinocerebellar Ataxia-34 Differentially Alter Very Long Chain Fatty Acid Biosynthesis	3
Detergent-induced quantitatively limited formation of diacyl phosphatidylinositol dimannoside in Mycobacterium smegmatis	3
Vascular lipid droplets formed in response to TNF, hypoxia, or OA: biochemical composition and prostacyclin generation	3
Dissecting cell type–specific impact in lysosomal acid lipase deficiency–associated disorders	3
Temporal dissociation of COX-2-dependent arachidonic acid and 2-arachidonoylglycerol metabolism in RAW264.7 macrophages	3
Saroglitazar is noninferior to fenofibrate in reducing triglyceride levels in hypertriglyceridemic patients in a randomized clinical trial	3
The metabolic signature of blood lipids: a causal inference study using twins	3
Identification of bile acid-CoA:amino acid N-acyltransferase as the hepatic N-acyl taurine synthase for polyunsaturated fatty acids	3