Journal of Lipid Research

Article	Citations
Plasma S1P and Sphingosine are not Different Prior to Pre-Eclampsia in Women at High Risk of Developing the Disease	152
Bioorthogonal azido-S1P works as substrate for S1PR1	95
Specific approaches and limitations in (multi)-omic Mendelian randomization	63
A simplified method for preventing postmortem alterations of brain prostanoids for true in situ level quantification	53
Cardiomyopathy in a c.1528G>C Hadha mouse is associated with cardiac tissue lipotoxicity and altered cardiolipin species	52
The role of lysosomal phospholipase A2 in the catabolism of bis(monoacylglycerol)phosphate and association with phospholipidosis	51
Elevation of hepatic de novo lipogenesis in mice with overnutrition is dependent on multiple substrates	47
TMEM241 is a UDP-N-acetylglucosamine transporter required for M6P modification of NPC2 and cholesterol transport	43
A comprehensive measure of Golgi sphingolipid flux using NBD C6-ceramide: evaluation of sphingolipid inhibitors	39
Four-dimensional lipidomics profiling in X-linked adrenoleukodystrophy using trapped ion mobility mass spectrometry	39
Nuclear lipid droplets in Caco2 cells originate from nascent precursors and in situ at the nuclear envelope	38
Development of a novel spatiotemporal depletion system for cellular cholesterol	37
Measuring Lp(a) particles with a novel isoform-insensitive immunoassay illustrates efficacy of muvalaplin	32
Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein	32
Altered hepatic lipid droplet morphology and lipid metabolism in fasted Plin2-null mice	28
Dietary docosahexaenoic acid (DHA) downregulates liver DHA synthesis by inhibiting eicosapentaenoic acid elongation	28
Lipidomics and mass spectrometry imaging unveil alterations in mice hippocampus lipid composition exposed to hypoxia	24
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In memoriam: Ana Jonas, PhD	24
Effects of exercise training on ANGPTL3/8 and ANGPTL4/8 and their associations with cardiometabolic traits	23
ABHD4 regulates adipocyte differentiation in vitro but does not affect adipose tissue lipid metabolism in mice	22
Creation of a novel zebrafish model with low DHA status to study the role of maternal nutrition during neurodevelopment	22
The role of high-density lipoproteins in sepsis	22
Choline kinase inhibition promotes ER-phagy	21

Hepatocytes Deficient in Nuclear Envelope Protein Lamina-associated Polypeptide 1 are an Ideal Mammalian System to Study Intranuclear Lipid Droplets	21
A fluorogenic substrate for the detection of lipid amidases in intact cells	20
Brown adipose tissue facilitates the fever response following infection with Salmonella enterica serovar Typhimurium in mice	19
Dietary modulation of Lp(a): more questions than answers	19
Introduction of a Lipidomics Scoring System for data quality assessment	19
The adipocyte apolipoprotein M is negatively associated with inflammation	19
KIAA1363 affects retinyl ester turnover in cultured murine and human hepatic stellate cells	19
Eicosapentaenoic Acid Ameliorates Cardiac Fibrosis and Tissue Inflammation in Spontaneously Hypertensive Rats	18
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The one-key-to-two-doors role of lipidomics: plasma lipidome, cardiovascular risk and statin usage	18
Effect of IL-6R blockade on plasma lipids and clinical outcomes among hospitalized patients with COVID-19 infection	18
Development and application of an LC-MS/MS method for the combined quantification of oxysterols and bile acids	18
Hepatic Deletion of X-Box Binding Protein 1 in FXR Null Mice Leads to Enhanced Liver Injury	18
Deep-lipidotyping by mass spectrometry: recent technical advances and applications	18
Efficacy of a novel PCSK9 inhibitory peptide alone and with evinacumab in a mouse model of atherosclerosis	17
TLR4 in POMC neurons regulates thermogenesis in a sex-dependent manner	17
Corrigendum to Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway	17
Metabolic switch from glycogen to lipid in the liver maintains glucose homeostasis in neonatal mice	16
The role of N-terminal phosphorylation of DGK-θ	16
DFCP1 is a regulator of starvation-driven ATGL-mediated lipid droplet lipolysis	16
Characterizing genetic profiles for high triglyceride levels in U.S. patients of African ancestry	15
2-Hydroxypropyl-β-cyclodextrin mitigates pathological changes in a mouse model of retinal cholesterol dyshomeostasis	15
Highly tail-asymmetric lipids interdigitate and cause bidirectional ordering	15
Dissecting cell type–specific impact in lysosomal acid lipase deficiency–associated disorders	15
Saroglitazar is noninferior to fenofibrate in reducing triglyceride levels in hypertriglyceridemic patients in a randomized clinical trial	15
Elevated high-density lipoprotein triglycerides increase atherosclerotic risk	15
Detergent-induced quantitatively limited formation of diacyl phosphatidylinositol dimannoside in Mycobacterium smegmatis	15
Diet-induced obesity dampens the temporal oscillation of hepatic mitochondrial lipids	15
In Memoriam: Jan B Sjövall, MD, PhD, (1928–2024)	14
Lipidomic analysis of Porphyromonas gingivalis reveals novel glycerol bisphosphoceramide, phosphatidyl-, and phosphoglycerol dipeptide lipid families	14
Heptanol-mediated phase separation determines phase preference of molecules in live cell membranes	14
Polyunsaturated fatty acids stimulate immunity and eicosanoid production in Drosophila melanogaster	14
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Phosphatidic Acid Mediates the Nem1-Spo7/Pah1 Phosphatase Cascade in Yeast Lipid Synthesis	14
Mice deficient in ER protein seipin have reduced adrenal cholesteryl ester lipid droplet formation and utilization	14
Fatty acid nitroalkenes regulate intestinal lipid absorption	14
A facile assay for zDHHC palmitoyl transferase activation elucidates effects of mutation and modification	14
Elevated n-3/n-6 PUFA ratio in early life diet reverses adverse intrauterine kidney programming in female rats	14
Glucosylceramide flippases contribute to cellular glucosylceramide homeostasis	14
Cardiolipin remodeling maintains the inner mitochondrial membrane in cells with saturated lipidomes	13
Phosphatidylserine-decorated delivery platform helps alleviate acute lung injury via potentiating macrophage targeting	13
Apolipoprotein A1 and high-density lipoprotein limit low-density lipoprotein transcytosis by binding SR-B1	13
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Metallothionein 1B attenuates inflammation and hepatic steatosis in MASH by inhibiting the AKT/PI3K pathway	13
Spatial lipidomics of coronary atherosclerotic plaque development in a familial hypercholesterolemia swine model	13
Associations between serum cholesterol and immunophenotypical characteristics of circulatory B cells and Tregs	13
Tripartite motif 38 alleviates the pathological process of NAFLD–NASH by promoting TAB2 degradation	13
Association of plasma ceramide with decline in kidney function in patients with type 2 diabetes	13
Repurposing daclatasvir for MASLD Therapy—A promising step forward with challenges ahead	13
Circadian PER1 controls daily fat absorption with the regulation of PER1-PKA on phosphorylation of bile acid synthetase	13

High-density lipoproteins mediate small RNA intercellular communication between dendritic cells and macrophages	13
GCKIII kinases control hepatocellular lipid homeostasis via shared mode of action	12
Decreased sarcoplasmic reticulum phospholipids in human skeletal muscle are associated with metabolic syndrome	12
HBV-miR-3 induces hepatic cholesterol accumulation by targeting ABCA1: evidence for potential benefits of statin usage	12
Liver proteomics identifies a disconnect between proteins associated with de novo lipogenesis and triglyceride storage	12
Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis	12
Consequences of excessive glucosylsphingosine in glucocerebrosidase-deficient zebrafish.	12
ORMDL mislocalization by impaired autophagy in Niemann-Pick type C disease leads to increased de novo sphingolipid biosynthesis	12
Participation of lipids in the tumor response to photodynamic therapy and its exploitation for therapeutic gain	12
Microbial products linked to steatohepatitis are reduced by deletion of nuclear hormone receptor SHP in mice	12
Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain	12
Dysregulation of mitochondrial dynamics and mitophagy are involved in high-fat diet-induced steroidogenesis inhibition	12
Intravital lipid droplet labeling and imaging reveals the phenotypes and functions of individual macrophages in vivo	12
Reducing saturated fat intake lowers LDL-C but increases Lp(a) levels in African Americans: the GET-READI feeding trial	12
Comprehensive mass spectrometry lipidomics of human biofluids and ocular tissues	12
Detecting white adipose tissue browning in mice with in vivo R2∗ mapping at 9.4T MRI	12
De(C1P)hering the role of ceramide-1-phosphate levels in skin wound healing	11
Unraveling the genetic background of individuals with a clinical familial hypercholesterolemia phenotype	11
Distinct pathways for the absorption and metabolism of β-carotene and zeaxanthin in the mouse intestine	11
Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice	11
Untargeted lipidomics reveals novel HDL metabotypes and lipid-clinical correlates	11
Hsp90α promotes lipogenesis by stabilizing FASN and promoting FASN transcription via LXRα in hepatocellular carcinoma	11
Substrate-dependent incorporation of 15-lipoxygenase products in glycerophospholipids: 15-HETE and 15-HEPE in PI, 17-HDHA in plasmalogen PE, and 13-HODE in PC	11
Comparison between genetic and pharmaceutical disruption of Ldlr expression for the development of atherosclerosis	11
Magnetic resonance imaging detects white adipose tissue beiging in mice following PDE10A inhibitor treatment	11
A multi-ancestry genome-wide association study and evaluation of polygenic scores of LDL-C levels	11
Quantitative characterizations of the cholesterol-related pathways in the retina and brain of hamsters	11
Measurement of 7-dehydrocholesterol and cholesterol in hair can be used in the diagnosis of Smith-Lemli-Opitz syndrome	11
Differential expression patterns of phospholipase D isoforms 1 and 2 in the mammalian brain and retina	11
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Hormone-sensitive lipase protects adipose triglyceride lipase-deficient mice from lethal lipotoxic cardiomyopathy	11
Strategies for consistent and automated quantification of HDL proteome using data-independent acquisition	11
Triglyceride-rich lipoprotein, remnant cholesterol, and apolipoproteins CII, CIII, and E in patients with schizophrenia	11
Causal association of blood lipids with all-cause and cause-specific mortality risk: a Mendelian randomization study	11
Alternative fatty acid desaturation pathways revealed by deep profiling of total fatty acids in RAW 264.7 cell line	11
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Competitive displacement of lipoprotein lipase from heparan sulfate is orchestrated by a disordered acidic cluster in GPIHBP1	10
Targeting to high density lipoprotein cholesterol: new insights for inflammatory bowel disease treatment	10
Insulin dysregulation drives mitochondrial cholesterol metabolite accumulation: initiating hepatic toxicity in nonalcoholic fatty liver disease	10
Sorting through the extensive and confusing roles of sortilin in metabolic disease	10
Characteristic distribution of eicosapentaenoic acid in human abdominal aortic aneurysm wall	10
Adipose Tissue, Bile Acids, and Gut Microbiome Species Associated With Gallstones After Bariatric Surgery	10
Unbiased insights into the multiplicity of the CYP46A1 brain effects in 5XFAD mice treated with low dose-efavirenz	10
APOA5 deficiency causes hypertriglyceridemia by reducing amounts of lipoprotein lipase in capillaries	10
Blocking Lipid Uptake Pathways Does not Prevent Toxicity in Adipose Triglyceride Lipase (ATGL) Deficiency	10
Potential causal evidence for an ApoB-independent and HDL-related risk profile associated with coronary artery disease	10
SDCCAG3 inhibits adipocyte hypertrophy and improves obesity-related metabolic disorders via SDCCAG3/SMURF1/PPARγ axis	9
Loss of Splicing Factor SRSF3 Impairs Lipophagy Through Ubiquitination and Degradation of Syntaxin17 in Hepatocytes	9
A high-cholesterol zebrafish diet promotes hypercholesterolemia and fasting-associated liver steatosis	9
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Sphingomyelin is involved in regulating UCP1-mediated nonshivering thermogenesis	9
The Non Catalytic Protein ERG28 has a Functional Role in Cholesterol Synthesis and is Coregulated Transcriptionally	9
6-O-alkyl 4-methylumbelliferyl-β-D-glucosides as selective substrates for GBA1 in the discovery of glycosylated sterols	9
Ceramide kinase regulates acute wound healing by suppressing 5-oxo-ETE biosynthesis and signaling via its receptor OXER1	9
The lipidomics reporting checklist a framework for transparency of lipidomic experiments and repurposing resource data	9
Flavonoids regulate LDLR through different mechanisms tied to their specific structures	9
Pharmacological SERCA activation limits diet-induced steatohepatitis and restores liver metabolic function in mice	9
Decoding the role of angiopoietin-like protein 4/8 complex–mediated plasmin generation in the regulation of LPL activity	9
Effects of apolipoprotein H downregulation on lipid metabolism, fatty liver disease, and gut microbiota dysbiosis	9
Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder	9
Peridroplet mitochondria are associated with the severity of MASLD and the prevention of MASLD by diethyldithiocarbamate	9
Associations between insulin-like growth factor binding protein-2 and lipoprotein kinetics in men	9
Pioglitazone alleviates lacrimal gland impairments induced by high-fat diet by suppressing M1 polarization	9
Mining cholesterol genes from thousands of mouse livers identifies aldolase C as a regulator of cholesterol biosynthesis	9
Vascular lipid droplets formed in response to TNF, hypoxia, or OA: biochemical composition and prostacyclin generation	9
A historical, evidence-based, and narrative review on commonly used dietary supplements in lipid-lowering	9
Brown fat fuels the fire in fever	9
Global deletion of COX-2 attenuates hepatic inflammation but impairs metabolic homeostasis in diet-induced obesity	9
The SGLT2 inhibitor dapagliflozin promotes systemic FFA mobilization, enhances hepatic β-oxidation, and induces ketosis	9
The DNA methyltransferase inhibitor decitabine blunts the response to a high-animal fat and protein diet in mice	9
Sphingosine kinase 1 is involved in triglyceride breakdown by maintaining lysosomal integrity in brown adipocytes	8
Apolipoprotein F concentration, activity, and the properties of LDL controlling ApoF activation in hyperlipidemic plasma	8
Acute retinol mobilization by retinol-binding protein 4 in mouse liver induces fibroblast growth factor 21 expression	8
A basic model for the association of ligands with membrane cholesterol: application to cytolysin binding	8
Human apoA-I[Lys107del] mutation affects lipid surface behavior of apoA-I and its ability to form large nascent HDL	8
A novel mutation, Ile344Asn, in microsomal triglyceride transfer protein abolishes binding to protein disulfide isomerase	8
Lipidomics of phospholipase A2 reveals exquisite specificity in macrophages	8
A targeted proteomics method for quantifying plasma apolipoprotein kinetics in individual mice using stable isotope labeling	8
LC-MS based simultaneous profiling of adrenal hormones of steroids, catecholamines, and metanephrines	8
2-fluoro-1-methylpyridinium p-toluene sulfonate: a new LC-MS/MS derivatization reagent for vitamin D metabolites	8

Unmasking crucial residues in adipose triglyceride lipase for coactivation with comparative gene identification-58	8
Potential causal and temporal relationship between plasma triglyceride levels and circulating leukocyte	8
A high-resolution 13C NMR approach for profiling fatty acid unsaturation in lipid extracts and in live Caenorhabditis elegans	8
Specific FAHFAs predict worsening glucose tolerance in non-diabetic relatives of people with Type 2 diabetes	8
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Relationship of apolipoprotein(a) isoform size with clearance and production of lipoprotein(a) in a diverse cohort	8
All-trans retinoic acid induces lipophagy by reducing Rubicon in Hepa1c1c7 cells	8
In Memoriam: G. Stephen (Steve) Tint, PhD (1935–2022)	8
Spatial lipidomics reveals zone-specific hepatic lipid alteration and remodeling in metabolic dysfunction-associated steatohepatitis	8
Hexokinase 2 promotes ISGylation of Acyl-CoA synthetase long-chain family member 4 in sepsis-induced microglia cells	8
The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases	8
Circulating membrane aminophospholipids contribute to thrombotic risk in rheumatoid arthritis	8
Does small HDL’s function improve when lipid-lowering alters its composition?	8
Determination of tissue contributions to the circulating lipid pool in cold exposure via systematic assessment of lipid profiles	8
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