Journal of Molecular and Cellular Cardiology

Papers
(The median citation count of Journal of Molecular and Cellular Cardiology is 0. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Vinculin haploinsufficiency impairs integrin-mediated costamere remodeling on stiffer microenvironments157
RyR2 phosphorylation at serine-2814 increases cardiac tolerance to arrhythmogenic Ca2+ alternans in mice91
Editorial Board88
Does coronary microvascular dysfunction play a role in heart failure with reduced ejection fraction?80
Endothelialization of coronary stents after intra-luminal adenoviral VEGF-A gene transfer in a preclinical porcine restenosis model – Studies with optical coherence tomography, angioscopy, multiphoton70
Mitochondrial protein hyperacetylation underpins heart failure with preserved ejection fraction in mice67
Prostaglandin E1 attenuates AngII-induced cardiac hypertrophy via EP3 receptor activation and Netrin-1upregulation61
Editorial Board60
Btg1 and Btg2 regulate neonatal cardiomyocyte cell cycle arrest60
Computation-assisted targeted proteomics of alternative splicing protein isoforms in the human heart58
Potential impacts of the cardiac troponin I mobile domain on myofilament activation and relaxation57
Txnip C247S mutation protects the heart against acute myocardial infarction54
Molecular remodeling of Cx43, but not structural remodeling, promotes arrhythmias in an arrhythmogenic canine model of nonischemic heart failure54
Impact of etiology on force and kinetics of left ventricular end-stage failing human myocardium54
Sarcoplasmic reticulum-mitochondria communication; implications for cardiac arrhythmia51
Aging in reverse: Reactivating developmental signaling for cardiomyocyte proliferation48
LITAF acts as a novel regulator for pathological cardiac hypertrophy46
Pharmacological and cell-specific genetic PI3Kα inhibition worsens cardiac remodeling after myocardial infarction45
An evolutionarily-conserved promoter allele governs HMG-CoA reductase expression in spontaneously hypertensive rat43
Functional genomics and epigenomics of atrial fibrillation39
Blocking endothelial TRPV4-Nox2 interaction helps reduce ROS production and inflammation, and improves vascular function in obese mice38
The mechanistic target of rapamycin complex 1 critically regulates the function of mononuclear phagocytes and promotes cardiac remodeling in acute ischemia38
With a grain of salt: Sodium elevation and metabolic remodelling in heart failure35
Computational modeling of aberrant electrical activity following remuscularization with intramyocardially injected pluripotent stem cell-derived cardiomyocytes34
Improved epicardial cardiac fibroblast generation from iPSCs34
Dual loss of regulator of G protein signaling 2 and 5 exacerbates ventricular myocyte arrhythmias and disrupts the fine-tuning of Gi/o signaling34
Improved Ca2+ release synchrony following selective modification of Itof and phase 1 repolarization in normal and failing ventricular myocytes31
ICAM-1-related noncoding RNA accelerates atherosclerosis by amplifying NF-κB signaling30
CaMKII and reactive oxygen species contribute to early reperfusion arrhythmias, but oxidation of CaMKIIδ at methionines 281/282 is not a determining factor29
Cardiac injection of USSC boosts remuscularization of the infarcted heart by shaping the T-cell response29
Adenosine kinase promotes post-infarction cardiac repair by epigenetically maintaining reparative macrophage phenotype28
Integrated proteomics reveals alterations in sarcomere composition and developmental processes during postnatal swine heart development28
Endothelial cell direct reprogramming: Past, present, and future27
Distinct effects of cardiac mitochondrial calcium uniporter inactivation via EMRE deletion in the short and long term27
Absence (of the uniporter) makes the heart grow fonder: The cardiac response to injury adapts after prolonged EMRE inhibition27
Differential bioenergetics in adult rodent cardiomyocytes isolated from the right versus left ventricle26
Loss of TIMP3, but not TIMP4, exacerbates thoracic and abdominal aortic aneurysm26
Integrated modeling and simulation of recruitment of myocardial perfusion and oxygen delivery in exercise26
mTORC1 regulates the metabolic switch of postnatal cardiomyocytes during regeneration26
Presenilin-1 ΔE9 mutation associated sarcoplasmic reticulum leak alters [Ca2+]i distribution in human iPSC-derived cardiomyocytes25
Titin's cardiac-specific N2B element is critical to mechanotransduction during volume overload of the heart25
Ventricular differences in mitochondrial Ca2+ dynamics in murine and porcine hearts24
Endogenous complement 1q binding protein (C1qbp) regulates mitochondrial permeability transition and post-myocardial infarction remodeling and dysfunction24
Exercise reduces pro-inflammatory lipids and preserves resolution mediators that calibrate macrophage-centric immune metabolism in spleen and heart following obesogenic diet in aging mice23
Elucidating effects of the environmental pollutant benzo[a]pyrene [BaP] on cardiac arrhythmogenicity23
Transient formation of collaterals contributes to the restoration of the arterial tree during cardiac regeneration in neonatal mice23
Myocardial glycophagy flux dysregulation and glycogen accumulation characterize diabetic cardiomyopathy23
Alda-1 attenuation of binge alcohol-caused atrial arrhythmias through a novel mechanism of suppressed c-Jun N-terminal Kinase-2 activity23
ZFP36L1 controls KLF16 mRNA stability in vascular smooth muscle cells during restenosis after vascular injury23
Panorama of artery endothelial cell dysfunction in pulmonary arterial hypertension23
Stochastic and alternating pacing paradigms to assess the stability of cardiac conduction22
cAMP/PKA signaling affects aged-deteriorated pacemaker beat interval dynamic: Antiaging approach22
Another-regulin regulates cardiomyocyte calcium handling via integration of neuroendocrine signaling with SERCA2a activity22
Cysteine 202 in Cyclophilin D inhibits the cardiac mitochondrial F1F0-ATPase22
Assessing and interpreting diastolic function in animal models of heart disease22
Prevalence of rare missense TTN variants in a cohort of patients with cardiomyopathy22
Can polarization of macrophage metabolism enhance cardiac regeneration?22
The differential metabolic, hypertensive, exercise, and ketone parameters in male vs. female heart failure with preserved ejection fraction21
Early desmin cytoskeleton remodeling in experimental cardiac hypertrophy20
Live imaging of translation in living cardiomyocytes at super-resolution20
LINCing the nucleus: Nuclear abnormalities and chromatin alterations in hypertrophic cardiomyopathy20
Investigating a novel role for nesprin-1 and the LINC complex in cardiomyocyte mechanotransduction19
Defining a specific timeline for periostin upregulation in cardiac fibrosis following myocardial infarction19
Cardioprotective effect of Fam3c after ischemic damage19
Disruption of sarcoplasmic reticulum-mitochondrial contacts underlies contractile dysfunction in experimental and human atrial fibrillation: A key role of mitofusin 219
Development of a mouse model for Sars-Cov-2 studies in the heart19
Neuro-cardiac organ-on-a-chip using patient specific induced pluripotent stem cells and microfluidic devices19
Dyrk1a kinase controls cardiomyocyte proliferation19
Slc25a12 regulates Opa1 oligomeric assembly and cristae maintenance which is implicated in cardiac pathophysiology19
Evaluation of the effect of LCZ696 in human iPSC-derived cardiomyocyte hypertrophy and tubulin detyrosination19
Gut microbial metabolite trimethylamine N-oxide induces aortic dissection18
Cardio-pulmonary interaction in HFpEF18
Elucidating the molecular mechanisms and cellular specificity of HDAC inhibitor efficacy in diastolic dysfunction18
Editorial Board18
Phosphorylation of RyR2 at S2814 is a necessary step for the protective effect of β-adrenergic stimulation against Ca2+ alternans18
PKD regulates myofibrillogenesis and intercalated disc composition18
Investigating Sodium-Glucose Co-Transporters 1 (SGLT1) in Myocardium and its role in hyperglycaemia Ischaemia-Reperfusion injury18
Editorial Board18
Mosaicism for the smooth muscle cell (SMC)-specific knock-in of the Acta2 R179C pathogenic variant: Implications for gene editing therapies17
Acute cardiac deletion of EMRE protects against ischemia reperfusion injury in an ex vivo Langendorff model17
Editorial Board17
Characterization of a mouse model with the most common hypertrophic cardiomyopathy mutation MYBPC3c.2373InsG in the Netherlands17
Tenascin C deficiency attenuates cardiac dysfunction, endothelial dysfunction and fibrosis in diabetic cardiomyopathy mice17
Inactivation of the local cardiac renin angiotensin system promotes post-infarction recovery17
β-adrenergic/cAMP signaling in doxorubicin-induced cardiotoxicity17
MBNL1 controls cardiomyocyte differentiated versus proliferative cell state17
CD14 inhibition mitigates left ventricular damage and dysfunction following myocardial infarction17
Investigation of the potential antiremodeling effects of the preimplantation factor in a rat model of radiation-induced heart disease17
CRIP1: A novel link between immune response and hypertension17
Identification of a novel cardiac epitope triggering T-cell responses in patients with myocardial infarction16
Metabolic flux in the driver's seat during cardiac health and disease16
High-sensitivity calcium biosensor on the mitochondrial surface reveals that IP3R channels participate to the reticular Ca2+leak towards mitochondria16
Germline deletion of the mitochondrial calcium uniporter (MCU) does not affect mitochondrial calcium increases during ischemia/reperfusion injury in ex vivo perfused mouse hearts16
Editorial Board16
CYP-Derived metabolites of Omega-3 fatty acids protect your heart16
Cardioprotective effects of novel NLRP3 inflammasome inhibitors15
Effects of omecamtiv mecarbil and mavacamten 461 in isolated human atrium15
Assessment of dose-dependent vasculoprotective effects of aronia extracts in mice aorta15
Targeting T-cell mediated inflammation improves cardiac dysfunction and metabolic remodelling in type 2 diabetes15
Development of a nanoencapsulated CBD formulation for delivery to a mouse model of heart failure with reduced ejection fraction15
“Disentangling” mitochondrial dysfunction in hypertrophic cardiomyopathy15
Abnormal mitochondrial calcium content in angiotensin-induced hypertrophy is ameliorated by cannabidiol mimicking PPAR-g activation15
Cardiomyocyte-autonomous mechanisms are sufficient to mediate load-dependent T-tubule remodeling in ventricular cardiomyocytes14
The extracellular signal-regulated kinases ERK1/2 are detrimental in ischemic stroke14
S100A1-SUMO interaction via SUMO interaction motif (SIM) of the S100A1 C-terminus domain is critical for S100A1 post-translational protein stability14
Myocardial power predicts 6-minute-walk test outcome after mitral valve surgery in patients with mitral insufficiency: A non-invasive CMR study14
Fluorescence spectroscopy investigation of the temporal evolution of β-adrenergic receptors expression at the plasma membrane in differentiating human induced pluripotent stem cells14
hiPSC derived cardiomyocytes as a tool to test the clinical significance and drug effectiveness in a novel mutation linked to CPVT14
Mitigation of monoamine oxidase-related endothelial dysfunction by antidiabetic medication in human mammary arteries14
Cyclic adenosine 3′-5′ monophosphate (cAMP) signaling and the major actors of the cardiac excitation contraction coupling (ECC) are differentially altered in diabetic cardiomyopathy14
Development of a pro-angiogenic injectable self-assembling biomaterial for the delivery of induced pluripotent stem cell derived cardiomyocytes to the heart14
Endocrine-microbiome-immune axis in sex-differential risk of heartfailure with preserved ejection fraction14
Molecular and functional characterization of a novel mutation in the cardiac ryanodine receptor (RyR2) associated with long QT syndrome14
Precision medicine approach for cardiometabolic risk factors in therapeutic apheresis14
Identification and functional epigenetic modulation of regulatory elements in cardiac myocytes14
Identification of Epac1 transcriptomic signature in ventricular myocytes14
Editorial Board13
Functional assays reveal the pathogenic mechanism of a de novo tropomyosin variant identified in patient with dilated cardiomyopathy13
Systematic characterization of SNPs associated with congenital heart disease.13
BAK contributes critically to necrosis and infarct generation during reperfused myocardial infarction13
Myocyte stiffening in hypertrophy is accompanied by compensatory chromatin decondensation13
Lactate formation in the heart following intravenous metformin administration with and without dobutamine pacing is seen by hyperpolarised D-[U-2H, U-13C]-glucose 13C magnetic resonance spectroscopy i13
Editorial Board13
IL-1β sensitizes mice to atrial fibrillation13
The neuronal isoform of nitric oxide synthase (nNOS) serves as the main inducer of PKA oxidation in the heart13
A critical review of wire injury induced aortic valve stenosis in mice13
Doxorubicin promotes a cardiac metabolic switch from an oxidative metabolism to glycolysis through a PI3Kγ-dependent mechanism13
Introduction to the special issue on stem cells and their products for cardiac repair and regeneration13
Inhibition of branched-chain amino acid oxidation aggravates adverse remodeling in the failing heart13
Ythdf2 regulates cardiac remodeling through its mRNA target transcripts13
Cardiac energy metabolism may play a fundamental role in congenital diaphragmatic hernia-associated ventricular dysfunction13
Does female sex matter in a chronic intermittent hypoxia mouse model?12
GDF10 promotes rodent cardiomyocyte maturation during the postnatal period12
MiR-185-5p regulates the development of myocardial fibrosis12
Metabolic therapy for managing heart failure with preserved ejection fraction12
Cardiomyocyte myofilament function in common animal models of heart failure with preserved ejection fraction12
Editorial Board12
Modeling ionizing radiation-induced cardiovascular dysfunction with human iPSC-derived engineered heart tissues12
CineCT platform for in vivo and ex vivo measurement of 3D high resolution Lagrangian strains in the left ventricle following myocardial infarction and intramyocardial delivery of theranostic hydrogel12
Corrigendum to “Activation of IGF-1 receptors and Akt signaling by systemic hyperinsulinemia contributes to cardiac hypertrophy but does not regulate cardiac autophagy in obese diabetic mice” [Journal12
Challenges in assessing myofilament calcium sensitivity and contractile function in HFpEF12
Bottom-up proteomic analysis of human adult cardiac tissue and isolated cardiomyocytes12
Diabetes mellitus and takotsubo syndrome: An unsettled association12
Enhanced NCLX-dependent mitochondrial Ca2+ efflux attenuates pathological remodeling in heart failure12
Current knowledge of pyroptosis in heart diseases11
The cell-autonomous and non–cell-autonomous roles of the Hippo pathway in heart regeneration11
Corrigendum to “Donor cell-type specific paracrine effects of cell transplantation for post-infarction heart failure” [J Mol Cell Cardiol 47 (2009) 288–295]11
Cardiac regeneration – Past advancements, current challenges, and future directions11
Genetic and functional analyses of TBX4 reveal novel mechanisms underlying pulmonary arterial hypertension11
Mitochondrial permeability transition pore-dependent necrosis11
RETRACTED: The novel antibody fusion protein rhNRG1-HER3i promotes heart regeneration by enhancing NRG1-ERBB4 signaling pathway11
Age-related structural and functional changes of the intracardiac nervous system11
Editorial Board11
Drp1/p53 interaction mediates p53 mitochondrial localization and dysfunction in septic cardiomyopathy11
Induction of GLI1 by miR-27b-3p/FBXW7/KLF5 pathway contributes to pulmonary arterial hypertension11
Signaling network model of cardiomyocyte morphological changes in familial cardiomyopathy11
Regulation of endogenous cardiomyocyte proliferation: The known unknowns11
The effects of xeno-free cryopreservation on the contractile properties of human iPSC derived cardiomyocytes11
Retraction notice to “The novel antibody fusion protein rhNRG1-HER3i promotes heart regeneration by enhancing NRG1-ERBB4 signaling pathway” [Journal of Molecular and Cellular Cardiology 187 (2023) 26–11
XCR1+ conventional dendritic cell-induced CD4+ T helper 1 cell activation exacerbates cardiac remodeling after ischemic myocardial injury11
Inhibition of miR-92a normalizes vascular gene expression and prevents diastolic dysfunction in heart failure with preserved ejection fraction11
Phosphodiesterase type 4 anchoring regulates cAMP signaling to Popeye domain-containing proteins10
Hippo/yes-associated protein signaling functions as a mechanotransducer in regulating vascular homeostasis10
The W792R HCM missense mutation in the C6 domain of cardiac myosin binding protein-C increases contractility in neonatal mouse myocardium10
Aging and HFpEF: Are we running out of time?10
CaMKIIδ post-translational modifications increase affinity for calmodulin inside cardiac ventricular myocytes10
Organ-on-a-chip systems for vascular biology10
Obscurin regulates ankyrin macromolecular complex formation10
Circadian biology of cardiac aging10
Visualization of cardiac thick filament dynamics in ex vivo heart preparations10
Nuclear receptor Nur77 protects against oxidative stress by maintaining mitochondrial homeostasis via regulating mitochondrial fission and mitophagy in smooth muscle cell10
Systems analysis of the mechanisms governing the cardiovascular response to changes in posture and in peripheral demand during exercise10
High frequency of anti-DSG 2 antibodies in post COVID-19 serum samples10
Autoinhibition of cMyBP-C by its middle domains10
Editorial Board9
Serine 663-dependent phosphorylation of SERCA2 in ischemic heart disease: Regulation of calcium homeostasis, cell death and myocardial infarct size9
Dysregulation of cardiac endothelial lncRNA H19 in COVID19 patients induces endothelial dysfunction, which impairs cardiomyocyte function9
Dual effect of cardiac FKBP12.6 overexpression on excitation-contraction coupling and the incidence of ventricular arrhythmia depending on its expression level9
Cannabis oil one-month oral treatment given to spontaneously hypertensive rats (SHR): Could it be a promising therapeutic strategy for hypertensive cardiac hypertrophy?9
Changes in extracellular matrix in failing human non-ischemic and ischemic hearts with mechanical unloading9
Elucidating the role of the L-type calcium channel in excitability and energetics in the heart: The ISHR 2020 Research Achievement Award Lecture9
Editorial Board9
Top papers and reviewers9
Targeting systolic heart failure: A newly developed troponin activator RPI-194 increases striated muscle contraction by acting as a calcium sensitizer9
Novel nanoparticle improves intracellular uptake and cardioprotective efficacy of DJ-1 mimic peptide9
Investigating the utilisation of human induced pluripotent stem cell-derived cardiomyocytes to study metabolic alterations in the heart of Duchenne muscular dystrophy patients9
Editorial Board9
Editorial Board9
The harder the climb the better the view: The impact of substrate stiffness on cardiomyocyte fate9
Persistent transcriptional changes in cardiac adaptive immune cells following myocardial infarction: New evidence from the re-analysis of publicly available single cell and nuclei RNA-sequencing data 9
The role of P21-activated kinase (Pak1) in sinus node function9
Macrophages amplify flecainide efficacy9
Ultrasonographic assessment of pulmonary and central venous congestion in experimental heart failure9
Antihypertensive and cardiac effect of Zn-Telmisartan in ovariectomized spontaneously hypertensive rats9
Loss of cyclophilin D prolyl isomerase activity desensitizes mitochondrial permeability transition pore opening in isolated cardiac mitochondria, but does not protect in myocardial ischemia-reperfusio9
A human CRYABR120G Desmin-related cardiomyopathy cellular model9
A novel transcription factor combination for direct reprogramming to a spontaneously contracting human cardiomyocyte-like state9
Conditional depletion of the acetyltransferase Tip60 protects against the damaging effects of myocardial infarction9
NAFLD as a continuous driver in the whole spectrum of vascular disease9
Role of ventrolateral part of ventromedial hypothalamus in post-myocardial infarction cardiac dysfunction induced by sympathetic nervous system9
Magnetic resonance hemodynamic forces predict pathological LVEDP in preserved LV-EF8
In the failing human heart, energetic dysfunction and hypertrophy are promoted by mitochondrial calcium overload through upregulation of the mitochondrial calcium uniporter8
Klotho deficiency exacerbates chronic hypoxicpulmonary hypertension in mice8
Long non-coding RNA UCA1 correlates with electrophysiological abnormalties in atrial fibrillation8
Alternative splicing of a transposable element into the human long noncoding RNA CARMEN is a switch for cardiac precursor cell specification8
Tebuconazole fungicide interacts with human Nav1.5 channels and alters the cellular excitability of cardiomyocytes derived from human induced pluripotent stem cells8
Investigation of the cardiotoxicity of full-length light chains derived from patients with cardiac light chain amyloidosis, multiple myeloma and monoclonal gammopathy of undetermined significance8
Single-nucleus transcriptomics reveals adipose tissue-derived signalling contributing to cardiovascular disease in a model of type-2 diabetes8
Investigating signaling mechanisms of structural cardiotoxicity via in situ single cell analysis by TOBis IMC on heterocellular cardiac organoids8
AKAP-mediated regulation of secretory processes in cardiac fibrosis8
Cardiac involvement in tumor-bearing mice8
Role of protein kinase A and calcium/calmodulin-dependent protein kinase II in beta-adrenergic regulation of potassium channels in canine ventricular cardiomyocytes8
Monoamine oxidase inhibitors attenuate the vascular hyperglycemic memory in diabetic mice8
The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes8
High-throughput measurements and characterization of iPSC-derived cardiomyocytes carrying isogenic troponin T mutations8
JAK1 Inhibitors reduce CRYABR120G aggregates in rat and human cardiomyocytes7
Functional remodeling of the mitochondrial Ca2+ uniporter complex in metabolic cardiomyopathy7
Is epicardial adipose tissue a key pathophysiologic target in heart failure with preserved ejection?7
Crosstalk between cell-matrix and cell-cell signaling in cardiomyocyte mechanosensing7
Uncovering metabolic drivers of heart failure with preserved ejection fraction (HFpEF)7
Activation of stress response signaling rewires cardiac metabolism in Barth syndrome7
Rubicon-regulated β1 adrenergic receptor recycling protects the heart from pressure overload7
Altered multicellular composition and unique myocyte phenotypes characterize the arrhythmogenic infarct border zone7
What is actually preserved in HFpEF? Focus on myocyte calcium handling remodelling7
Association of peripheral edema on body composition analysis in patients with heart failure7
Insulin-like growth factor-1 production by neonatal mouse cardiac fibroblasts in response to growth hormone is defective and dispensable for hypertrophy of neonatal mouse cardiomyocytes7
Proteomic screening in a rat model of HFpEF reveals key pathway modifications due to obesity7
Improving insights into the heterogeneous HFpEF syndrome through microvascular research7
Metformin improves diastolic function and cardiac lipid accumulation in type 1 diabetes7
Phosphoproteomic profiling of isolated murine cardiomyocytes reveals a role for protein phosphatase 2A (PP2A) regulatory subunit B55α as a regulator of β-adrenergic receptor signaling in the heart7
Ventricular SK2 upregulation following angiotensin II challenge: Modulation by p21-activated kinase-17
Tmem65 is critical for the structure and function of the intercalated discs in mouse hearts7
MicroRNA-199b is involved in both LV and RV pathological remodeling through distinct molecular mechanisms7
Role of exchange protein directly activated by cAMP 1 in cardiac aging7
The cardiomyocyte mechanical code – Mechanical imprinting of talin interactions regulate cardiomyocyte mechanosensing and function7
Cardio-protective function of Junctophilin-2 is potentially mediated by nuclear translocation of its Calpain-specific N-terminal cleavage fragment7
Reconstructing intercalated disk nanostructure and molecular organization to unravel conduction differences between Atria and Ventricles – A combined microscopy and modeling study7
Proteomic approaches to assess ischemia-reperfusion (stunning) injury to the heart7
Editorial Board7
Immune checkpoint inhibitor cardiotoxicity: Breaking barriers in the cardiovascular immune landscape6
Heart failure with preserved ejection fraction: An age-related condition6
The ins and outs of cellular pH during cardiac ischemia6
Reduced O-GlcNAcylation diminishes cardiomyocyte Ca2+ dependent facilitation and frequency dependent acceleration of relaxation6
YAP inhibition promotes endothelial cell differentiation from pluripotent stem cell through EC master transcription factor FLI16
Genetics of cancer therapy-associated cardiotoxicity6
Hydrogel delivery of purinergic enzymes improves cardiac ischemia/reperfusion injury6
Mechanisms and strategies for a therapeutic cardiac immune response6
Multilayer control of cardiac electrophysiology by microRNAs6
Direct proteomic and high-resolution microscopy biopsy analysis identifies distinct ventricular fates in severe aortic stenosis6
Distinct effects of intracellular vs. extracellular acidic pH on the cardiac metabolome during ischemia and reperfusion6
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