OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Molecular Evolution is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Correction: Stochastic Epigenetic Modification and Evolution of Sex Determination in Vertebrates	49
Molecular Evolution of Malacostracan Short Wavelength Sensitive Opsins	34
Correction: Analysis of Cancer-Resisting Evolutionary Adaptations in Wild Animals and Applications for Human Oncology	33
Modified Metabolism and Response to UV Radiation: Gene Expression Variations Along an Elevational Gradient in the Asiatic Toad (Bufo gargarizans)	32
Extant Sequence Reconstruction: The Accuracy of Ancestral Sequence Reconstructions Evaluated by Extant Sequence Cross-Validation	27
Prebiotic N-(2-Aminoethyl)-Glycine (AEG)-Assisted Synthesis of Proto-RNA?	22
Scaling up Functional Analyses of the G Protein-Coupled Receptor Rhodopsin	21
The Ancient Origins of Death Domains Support the ‘Original Sin’ Hypothesis for the Evolution of Programmed Cell Death	19
Embracing Complexity: Yeast Evolution Experiments Featuring Standing Genetic Variation	19
Unusual Evolution of Cephalopod Tryptophan Indole-Lyases	16
Screening for Viruses in Pallas’s Long-Tongued Bats (Glossophaga soricina) in Brazil	15
Learning from the Codon Table: Convergent Recoding Provides Novel Understanding on the Evolution of A-to-I RNA Editing	15
An Ultimate Question for Functional A-to-I mRNA Editing: Why Not a Genomic G?	15
Odorant-Binding and Chemosensory Proteins in Fig Wasps: Evolutionary Insights From Comparative Studies	13
Understanding Functional Evolution in Orthologs and Paralogs	13
Overlaps Between CDS Regions of Protein-Coding Genes in the Human Genome: A Case Study on the NR1D1-THRA Gene Pair	12
Organophosphorus Compound Formation Through the Oxidation of Reduced Oxidation State Phosphorus Compounds on the Hadean Earth	12
Post-Subfunctionalization Functions of HIF-1αA and HIF-1αB in Cyprinid Fish: Fine-Tuning Mitophagy and Apoptosis Regulation Under Hypoxic Stress	12
dN/dS-H, a New Test to Distinguish Different Selection Modes in Protein Evolution and Cancer Evolution	11
Phylogenetic and Evolutionary Analysis of Plant Small RNA 2′-O-Methyltransferase (HEN1) Protein Family	11
On Protein Loops, Prior Molecular States and Common Ancestors of Life	11
Evolution of Transcript Abundance is Influenced by Indels in Protein Low Complexity Regions	11
Possible Acquisition and Molecular Evolution of vpu Genes Inferred from Comprehensive Sequence Analysis of Human and Simian Immunodeficiency Viruses	10
On the Nature of the Last Common Ancestor: A Story from its Translation Machinery	10
Conservation of Protein Kinase A Substrates in the Cnidarian Coral Spermatozoa Among Animals and Their Molecular Evolution	10

A Closer Look at Non-random Patterns Within Chemistry Space for a Smaller, Earlier Amino Acid Alphabet	10
Biochemical Property Based Positional Matrix: A New Approach Towards Genome Sequence Comparison	10
Molecular Footprints on Osmoregulation-Related Genes Associated with Freshwater Colonization by Cetaceans and Sirenians	10
The Last Universal Common Ancestor of Ribosome-Encoding Organisms: Portrait of LUCA	9
Adaptation and Exaptation: From Small Molecules to Feathers	9
Understanding the Origin and Evolution of Tea (Camellia sinensis [L.]): Genomic Advances in Tea	9
A New View of the Last Universal Common Ancestor	8
Evolution and Functional Diversification of Serine Racemase Homologs in Bacteria	8
RNA or DNA? Revisiting the Chemical Nature of the Cenancestral Genome	8
Functional Diversity of the Lepidopteran ATP-Binding Cassette Transporters	8
Reduction of Tooth Replacement Disproportionately Affects the Evolution of Enamel Matrix Proteins	8
The De Novo Emergence of Two Brain Genes in the Human Lineage Appears to be Unsupported	8
Codon Usage Evolution in Viruses: Implications for Survival and Pathogenicity	8
Biothermodynamics of Hemoglobin and Red Blood Cells: Analysis of Structure and Evolution of Hemoglobin and Red Blood Cells, Based on Molecular and Empirical Formulas, Biosynthesis Reactions, and Therm	8
Cystathionine Gamma-Lyase: A Potential Longevity Gene Under Selection?	8
Informatic Capabilities of Translation and Its Implications for the Origins of Life	7
Correction: Sequence Divergence in Venom Genes Within and Between Montane Pitviper (Viperidae: Crotalinae: Cerrophidion) Species is Driven by Mutation–Drift Equilibrium	7
EasyDIVER + : An Advanced Tool for Analyzing High Throughput Sequencing Data from In Vitro Evolution of Nucleic Acids or Amino Acids	7
Analysis of the MCTP Amino Acid Sequence Reveals the Conservation of Putative Calcium- and Lipid-Binding Pockets Within the C2 Domains In Silico	7
Promiscuous Domains in Eukaryotes and HAT Proteins in FUNGI Have Followed Different Evolutionary Paths	7
GC Content Across Insect Genomes: Phylogenetic Patterns, Causes and Consequences	7
PAReTT: A Python Package for the Automated Retrieval and Management of Divergence Time Data from the TimeTree Resource for Downstream Analyses	7
Deep Conservation and Unexpected Evolutionary History of Neighboring lncRNAs MALAT1 and NEAT1	7
FEZF2 and AIRE1: An Evolutionary Trade-off in the Elimination of Auto-reactive T Cells in the Thymus	7
Best Practices in Designing, Sequencing, and Identifying Random DNA Barcodes	7
A Law of Redundancy Compounds the Problem of Cancer and Precision Medicine	7
Context-Dependent Mutation Dynamics, Not Selection, Explains the Codon Usage Bias of Most Angiosperm Chloroplast Genes	7
Caspase Domain Duplication During the Evolution of Caspase-16	7
Transposable Element Diversity Remains High in Gigantic Genomes	6
Putative MutS2 Homologs in Algae: More Goods in Shopping Bag?	6
Evidence for Multiple Independent Expansions of Fox Gene Families Within Flatworms	6
Main Factors Shaping Amino Acid Usage Across Evolution	6
Correction: Principles of Molecular Evolution: Concepts from Non-equilibrium Thermodynamics for the Multilevel Theory of Learning	6
Origins and Functional Significance of Eukaryotic Protein Folds	6
Evolutionary Nonindependence Between Human piRNAs and Their Potential Target Sites in Protein-Coding Genes	6
Co-evolution of alpha-helical transmembrane protein residues: large-scale variant profiling and complete mutational landscape of 2277 known PDB entries representing 504 unique human protein sequences	5
APGW/AKH Precursor from Rotifer Brachionus plicatilis and the DNA Loss Model Explain Evolutionary Trends of the Neuropeptide LWamide, APGWamide, RPCH, AKH, ACP, CRZ, and GnRH Families	5
A Genomic Conceptualization of Species	5
Jump-Chain Simulation of Markov Substitution Processes Over Phylogenies	5
Selection Pressure Regulates the Evolution-Structure–Function Paradigm of Monocyte Chemoattractant Protein Family	5
Tracking the Diversity and Chromosomal Distribution of the Olfactory Receptor Gene Repertoires of Three Anurans Species	5
Case Studies in the Assessment of Microbial Fitness: Seemingly Subtle Changes Can Have Major Effects on Phenotypic Outcomes	5
Context-Dependent Substitution Dynamics in Plastid DNA Across a Wide Range of Taxonomic Groups	5
The Mystery of Cancer Resistance: A Revelation Within Nature	5
Is the Association of the Rare rs35667974 IFIH1 Gene Polymorphism With Autoimmune Diseases a Case of RNA Epigenetics?	5
2022 Zuckerkandl Prize	5
Genomic AT Bias Coupled with Amino Acid Metabolism Modulates Codon Usage	5