OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Neuropathology and Experimental Neurology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Charcot Bouchard aneurysm: Case report and critical literature review	45
Extensive Postnatal Brainstem Calcification in a Premature Infant	39
Dual white matter pathology in fetal holoprosencephaly featuring concurrent malformative and destructive features: A case series	39
Pediatric Gliomas Presenting with Gliomatosis-Like Spread, Lack of Contrast Enhancement, EGFR Mutation, and TERT Promoter Variants	33
Transdifferentiation of metastatic melanoma into cerebellar angiosarcoma	26
AMPA receptors in Alzheimer disease: Pathological changes and potential therapeutic targets	25
Revealing the potential role of hsa-miR-663a in modulating the PI3K-Akt signaling pathway via miRNA microarray in spinal muscular atrophy patient fibroblast-derived iPSCs	25
Tissue clearing to examine glioma complexity in 3 dimensions	24
In This Issue	24
ANKRD22 promotes glioma proliferation, migration, invasion, and epithelial-mesenchymal transition by upregulating E2F1-mediated MELK expression	24
MicroRNA-155-5p Targets SKP2, Activates IKKβ, Increases Aβ Aggregation, and Aggravates a Mouse Alzheimer Disease Model	23
Diagnostic yield of postmortem brain examination following premortem brain biopsy for neoplastic and nonneoplastic disease	22
In This Issue	21
A novel grading system combining histological grade and CDKN2A homozygous and hemizygous deletion to predict prognosis in IDH-mutant astrocytoma	21
Limbic-predominant age-related TDP-43 encephalopathy (LATE-NC): Co-pathologies and genetic risk factors provide clues about pathogenesis	18
Evaluation of 6 monoclonal antibodies against Ser129-phosphorylated α-synuclein: Critical role of proteinase K antigen retrieval and superior sensitivity of the D1R1R clone in human skin biopsies	18
Persistent increase of Nogo-A-positive cells and dynamic reduction in oligodendroglia lineage cells in white matter regions following experimental and clinical traumatic brain injury	17
The comprehensive morphological and molecular characteristics of lipoastrocytoma: A case report	17
Altered expression of human myxovirus resistance protein A in amyotrophic lateral sclerosis	17
Sevoflurane anesthesia during late gestation induces cognitive disorder in rat offspring via the TLR4/BDNF/TrkB/CREB pathway	17
Identification of disease-associated molecular signatures in the Prp-TDP-43A315T mouse model of ALS: Toward preclinical biomarker development	17
Pathological Characteristics of Malformations of Cortical Development in Golden Syrian Hamsters with LDLR Deficiency	17
Phosphorylation of Tau at Threonine 231 in Patients With Multiple System Atrophy and in a Mouse Model	17
Could conditioned medium be used instead of stem cell transplantation to repair spinal cord injury in animal models? Identifying knowledge gaps	17
In This Issue	16

Meritorious Contributions to Neuropathology	16
Corrigendum to: Cerebellar Pilocytic Astrocytoma with a Sacral Drop Metastasis in an Adult	15
C9orf72 proline-arginine dipeptide repeats disrupt the proteasome and perturb proteolytic activities	14
Contribution of major histocompatibility complex class II immunostaining in distinguishing idiopathic inflammatory myopathy subgroups: A histopathological cohort study	14
Increased inflammasome protein expression identified in microglia from postmortem brains with schizophrenia	14
Aberrant accumulation of phosphorylated BRCA1 in brainstem-type and cortical-type Lewy bodies in Lewy body disease	14
Concurrent Pit-1 and SALL4 staining in primitive component of pituitary blastoma: A case report with clinicopathologic features including Cushing syndrome presentation, germline DICER1 mutation	13
Neuropathological features of SARS-CoV-2 delta and omicron variants	13
Therapeutic potential and challenges of mesenchymal stem cells in neurological disorders: A concise analysis	13
METTL3-mediated maturation of miR-192-5p targets ATG7 to prevent Schwann cell autophagy in peripheral nerve injury	13
Multifocal demyelinating leukoencephalopathy and oligodendroglial lineage cell loss with immune effector cell-associated neurotoxicity syndrome (ICANS) following CD19 CAR T-cell therapy for mantle cel	13
ZFTA-fused supratentorial ependymoma with a novel fusion partner, DUX4	13
Automated deep learning segmentation of neuritic plaques and neurofibrillary tangles in Alzheimer disease brain sections using a proprietary software	13
Performance of a condensed protocol to assess limbic-predominant age-related TDP-43 encephalopathy neuropathologic change	12
Immune Microenvironment and Lineage Tracing Help to Decipher Rosette-Forming Glioneuronal Tumors: A Multi-Omics Analysis	12
Significant contralaterality of temporal-predominant neuroastroglial tauopathy and FTLD-TDP type C presenting with the right temporal variant FTD	12
Long noncoding RNA KCNQ1OT1 aggravates cerebral infarction by regulating PTBT1/SIRT1 via miR-16-5p	12
COVID-19 could worsen cerebral amyloid angiopathy	12
Acupuncture at ST36 Alleviates the Behavioral Disorder of Autistic Rats by Inhibiting TXNIP-Mediated Activation of NLRP3	11
In This Issue	11
Detection of Gram-positive and Gram-negative bacteria in brain abscesses by 16S rRNA in situ hybridization	11
Histological appearance of topical hemostatic agents and materials in neuropathology	11
Acquired intradiploic epidermoid cyst: A rare case report with literature review	11
Angiogenic responses are enhanced by recombinant human erythropoietin in a model of periventricular white matter damage of neonatal rats through EPOR-ERK1 signaling	11
Distinct Patterns of Amyloid Pathology in Autopsies of Transthyretin S77Y and A97S Amyloidosis: Significance of Symptomatology and Cell Biology	11
In This Issue	11
In This Issue	11
In This Issue	10
Neuropathologic Findings in Elderly HIV-Positive Individuals	10
FGFR1 fusions in genomically and epigenetically bona fide glioblastoma, IDH-wildtype	10
Abnormal phosphorylation of protein tyrosine in neurodegenerative diseases	10
Persistence of Kii amyotrophic lateral sclerosis after the 2000s and its characteristic aging-related tau astrogliopathy	10
In This Issue	10
Adenocarcinoma Arising in a Yolk Sac Tumor of the Pineal Gland	10
Historical review: The golden age of the Golgi method in human neuropathology	10
What every neuropathologist needs to know: Update on neuro infectious disease workups and consultation resources	10
Correction to: Polymicrogyria with Dysmorphic Neurons in a Patient with SCN2A Mutation	10
In This Issue	10
A Rare Presentation of Low-Grade Prostate Adenocarcinoma as Delayed Pineal Region Metastasis: A Case Report and Review of Multicenter Clinical Experience in Prostate Carcinoma Brain Metastases	10
Activating BRAF G469A Missense Mutation in a Pediatric Patient With High-Grade Glioma	10
Correction to: Novel Glial Fibrillary Acidic Protein Variant in a Probable Adult-Onset Alexander Disease	10
Novel RAF Fusions in Pediatric Low-Grade Gliomas Demonstrate MAPK Pathway Activation	9
Perinatal hypoxic-ischemic brain injury: What’s behind the “ribbon effect”?	9
Paraneoplastic Lower Motor Neuron Disease	9
A Comparative Study of Site-Specific Distribution of Aging-Related Tau Astrogliopathy and Its Risk Factors Between Alzheimer Disease and Cognitive Healthy Brains: The Hisayama Study	9
Merlin immunoreactivity fails to predict neurofibromatosis type 2 mutations in human meningiomas	9
Analysis of a large case series of fatal familial insomnia to determine tests with the highest diagnostic value	9
Optimized Flow Cytometry Strategy for Phenotyping Intramuscular Leukocytes: Application to the Evaluation of Myopathological Processes	9
Novel Glial Fibrillary Acidic Protein Variant in a Probable Adult-Onset Alexander Disease	9
A rare case of fibromuscular dysplasia involving the cervicocephalic arterial tree highlighting the neuropathological findings	9

Discrepancy between Mild Muscle Pathology and Severe Muscular Compromise in COVID-19 Suggests Nonviral Etiologies	9
Microglia Activation in the Midbrain of the Human Neonate: The Effect of Perinatal Hypoxic-Ischemic Injury	8
Low clinical sensitivity and unexpectedly high incidence for neuropathologically diagnosed progressive supranuclear palsy	8
Progestin-associated meningiomatosis with unusual schwannoma-like morphology	8
NOD-like receptor X1 promotes autophagy and inactivates NLR family pyrin domain containing 3 inflammasome signaling by binding autophagy-related gene 5 to alleviate cerebral ischemia/reperfusion-induc	8
Differential Vulnerability of Hippocampal Subfields in Primary Age-Related Tauopathy and Chronic Traumatic Encephalopathy	8
In This Issue	8
Temporal progression of axonal degeneration in the visual system in experimental autoimmune encephalomyelitis: Insights from high-resolution neuropathology	8
NAA10 overexpression dictates distinct epigenetic, genetic, and clinicopathological characteristics in adult gliomas	8
Efficacy of deep brain stimulation for neuronal intranuclear inclusion disease tremor-dominant subtype	8
Prevalence of Lewy pathology in essential tremor is twice as high as expected: A plausible explanation for the enhanced risk for Parkinson disease seen in essential tremor cases	8
Neuropathologic Findings in Galloway-Mowat Syndrome 3 With a Novel OSGEP Variant	8
Reactive astrocytes in spinal cord injury: An analysis of heterogeneity based on temporality and spatiality, potential therapies, and limitations	8
In This Issue	8
Donald L. Price, MD 1935–2023	8
Subarachnoid Fibrosis in Human Post-Traumatic Syringomyelia: A Prospective Observational Clinical Study	7
Alzheimer disease-associated tau post-translational modification mimics impact tau propagation and uptake	7
Appreciation of Reviewers	7
Entrapped Megakaryocytes in the Microvasculature of Brain Tissues are not Specific to COVID-19 but can be Seen Across a Spectrum of Acute Lung Injuries	7
Molecular Alterations in Meningioangiomatosis Causing Epilepsy	7
DNA methylation profiling and histologic analysis of sellar TTF-1-positive papillary epithelial tumor supports a novel CNS entity	7
LncRNA HAGLR promotes the proliferation, migration, and neurotrophic factor production of Schwann cells via miR-204/CDK5R1 after sciatic nerve injury	7
Biopsy-proven granulomatous neuromyopathy in a case of Blau syndrome	7
E-cadherin expression and gene expression profiles in corticotroph pituitary neuroendocrine tumor subtypes	7
Chronic traumatic encephalopathy and aging-related tau astrogliopathy in community-dwelling older persons with and without moderate-to-severe traumatic brain injury	7
Chronic traumatic encephalopathy pathognomonic lesions occurring in isolation adjacent to infiltrative and non-infiltrative white matter lesions	7
Antemortem radiologic and histopathologic presentation of Marchiafava-Bignami disease	6
In This Issue	6
A Rare Diagnostic Challenge: Choroid Plexus Xanthogranuloma Harboring a Low-Grade Marginal Zone B-Cell Lymphoma	6
Dexmedetomidine Inhibits NF-κB-Transcriptional Activity in Neurons Undergoing Ischemia-Reperfusion by Regulating O-GlcNAcylation of SNW1	6
The Epigenetic Regulator Jumonji Domain-Containing Protein 6 (JMJD6) Is Highly Expressed but Not Prognostic in IDH-Wildtype Glioblastoma Patients	6
Polymorphous Low-Grade Neuroepithelial Tumor of the Young (PLNTY): Molecular Profiling Confirms Frequent MAPK Pathway Activation	6
Bone Marrow Stem Cell-Exo-Derived TSG-6 Attenuates 1-Methyl-4-Phenylpyridinium+-Induced Neurotoxicity via the STAT3/miR-7/NEDD4/LRRK2 Axis	6
Chronological Changes in the Expression Pattern of Hippocampal Prion Proteins During Disease Progression in Sporadic Creutzfeldt-Jakob Disease MM1 Subtype	6
A Pathologically Verified Case of Peripheral Intracranial Aneurysmal Formation With Massively Infiltrating Meningioma Cells	6
A pleomorphic xanthoastrocytoma highlighting the morphological heterogeneity of this uncommon tumor	6
α-Synuclein distribution in olfactory mucosa and skin nerves in Parkinson disease associated with an EIF4G1 gene mutation	5
Hippocampal synaptic alterations associated with tau pathology in primary age-related tauopathy	5
Bioengineered Models to Study Microenvironmental Regulation of Glioblastoma Metabolism	5
Fast Progression in Amyotrophic Lateral Sclerosis Is Associated With Greater TDP-43 Burden in Spinal Cord	5
β-Amyloid species production and tau phosphorylation in iPSC-neurons with reference to neuropathologically characterized matched donor brains	5
Prostate-Specific Membrane Antigen Expression in Meningioma: A Promising Theranostic Target	5
Different cortical and subcortical astroglial responsiveness in rats with acute liver failure	5
Alterations in the RB Pathway With Inactivation of RB1 Characterize Glioblastomas With a Primitive Neuronal Component	5
A comparison of CDKN2A status in gliomas using different techniques: The loss of p16 as a surrogate marker	5
In This Issue	5
Neuropathology of classic myotonic dystrophy type 1 is characterized by both early initiation of primary age-related tauopathy of the hippocampus and unique 3-repeat tauopathy of the brainstem	5
In This Issue	5
In situ seeding assay: A novel technique for direct tissue localization of bioactive tau	5
PAS+/PASD- intracytoplasmic glycogen is not specific for clear cell meningioma	5
Comparative analysis of histopathological parameters, genome-wide copy number alterations, and variants in genes involved in cell cycle regulation in chordomas of the skull base and sacrum	5
Comorbidities in early-onset sporadic versus presenilin-1 mutation-associated Alzheimer disease dementia: Evidence for dependency on Alzheimer disease neuropathological changes	4
Intracellular calcium dysregulation in heart and brain diseases: Insights from induced pluripotent stem cell studies	4
In This Issue	4
Pathology Features of Immune and Inflammatory Myopathies, Including a Polymyositis Pattern, Relate Strongly to Serum Autoantibodies	4
Cortical variant multiple sclerosis presenting clinically as Lewy body dementia	4
Clinical Importance of Molecular Testing in Neuromuscular Choristomas	4
Skin Biopsy as a Novel Diagnostic Aid in Immune-Mediated Neuropathies	4
In severe ADNC, hippocampi with comorbid LATE-NC and hippocampal sclerosis have substantially more astrocytosis than those with LATE-NC or hippocampal sclerosis alone	4
Medial Gap: A Structural Factor at the Arterial Bifurcation Aggravating Hemodynamic Insult	4
Preanalytic variable effects on segmentation and quantification machine learning algorithms for amyloid-β analyses on digitized human brain slides	4
Expanding the differential diagnosis for dural-based spindle cell neoplasms: A report of a rare GLI1-altered mesenchymal tumor of the CNS	4
Frontotemporal Lobar Degeneration With Unclassifiable 4-Repeat Tauopathy Mimicking Globular Glial Tauopathy	4
Molecular characterization of benign intracranial glioependymal and arachnoid cysts suggest heterogeneous mechanisms of action	4
Impact of COVID-19 pandemic on neuropathology service: Experience at one Canadian center	4
In This Issue	4
A custom next-generation sequencing panel for 1p/19q codeletion and mutational analysis in gliomas	4
Digital Histological Study of Neocortical Grey and White Matter Tau Burden Across Tauopathies	4
Authors’ response to: “Alexander disease genetics: Beyond GFAP exon sequencing?”	4
Cavernous sinus hemangioma: Histopathological spectrum of 8 cases	4