Journal of Pathology

Article	Citations
Intravenous iron treatment fuels chronic kidney disease‐induced arterial media calcification in rats	104
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Spatial profiling of ANO7 in prostate tissue: links to AR‐signalling‐associated lipid metabolism and inflammation	87
Breathing in danger: how particulate matter pollution is putting the public at risk of lung cancer†	84
High‐resolution and quantitative spatial analysis reveal intra‐ductal phenotypic and functional diversification in pancreatic cancer	79
Integration of peripheral blood‐ and tissue‐based biomarkers of response to immune checkpoint blockade in urothelial carcinoma	78
A new FGF15/19‐mediated gut‐to‐heart axis controls cardiac hypertrophy	71
Ovarian high‐grade serous carcinoma cells with low SMARCA4 expression and high SMARCA2 expression contribute to platinum resistance	70
CXCR4 mediates leukemic cell migration and survival in the testicular microenvironment	61
Clinical outcomes and immune contexture in SMARCA4 ‐deficient gastric cancer patients	58
‘Know thyself’ – host factors influencing cancer response to immune checkpoint inhibitors	55
Novel prognostication biomarker adipophilin reveals a metabolic shift in uveal melanoma and new therapeutic opportunities	53
The association between the tumor immune microenvironments and clinical outcome in low‐grade, early‐stage endometrial cancer patients	50
Artificial intelligence to identify genetic alterations in conventional histopathology	49
Collagen VI promotes recovery from colitis by inducing lymphangiogenesis and drainage of inflammatory cells	45
Presence of Tim3+ and PD‐1+CD8+T cells identifies microsatellite stable colorectal carcinomas with immune exhaustion and di	44
Escape from senescence: molecular basis and therapeutic ramifications	43
Identification of tumour‐infiltrating myeloid subsets associated with overall survival in lung squamous cell carcinoma	43
Platelet C3G protects from liver fibrosis, while enhancing tumor growth through regulation of the immune response	42
Pseudobudding: ruptured glands do not represent true tumor buds	42
CRISPR –Cas9 screening identifies the role of FER as a tumor suppressor	40
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Silencing GRHL3 promotes multiple organ distant metastasis of lung squamous cell carcinoma cells by enhancing SOX2 stability via SIRT1	38
Integrating computational pathology and proteomics to address tumor heterogeneity	37
Identification of actionable targets using DEPArray ‐based sorting of pure carcinoma and stromal populations from formalin‐fixed paraffin‐embedded ti	35

Human scattered tubular cells represent a heterogeneous population of glycolytic dedifferentiated proximal tubule cells	35
The E2F1–HOXB9/PBX2–CDK6 axis drives gastric tumorigenesis and serves as a therapeutic target in gastric cancer	35
In high‐grade ovarian carcinoma, platinum‐sensitive tumor recurrence and acquired‐resistance derive from quiescent residual cancer cells that overexpress CRYAB, CEACAM6, and	35
Field cancerization in breast cancer	34
Genomic features of Helicobacter pylori‐naïve diffuse‐type gastric cancer	34
KMT2D deficiency potentiates antitumor immunity and sensitizes immune checkpoint blockade in urologic cancers	33
Minigene‐based splicing analysis and ACMG/AMP‐based tentative classification of 56 ATM variants	32
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Genetic and epigenetic alterations in precursor lesions of endometrial endometrioid carcinoma	31
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Primary thyroid B‐cell lymphoma: molecular insights into its clonal evolution and relapse	30
Adrenomedullin2 stimulates progression of thyroid cancer in mice and humans under nutrient excess conditions	29
Downregulated BMP –Smad1/5/8 signaling causes emphysema via dysfunction of alveolar type II epithe	28
Development of a multi‐scanner facility for data acquisition for digital pathology artificial intelligence	28
Integrative analysis of genomic and transcriptomic data of normal, tumour, and co‐occurring leukoplakia tissue triads drawn from patients with gingivobuccal oral cancer identifies signatures of tumour	28
Prediction of coexisting invasive carcinoma on ductal carcinoma in situ (DCIS) lesions by mass spectrometry imaging	28
On the origin of gastric tumours: analysis of a case with intramucosal gastric carcinoma and oxyntic gland adenoma	27
Somatic loss of ATM is a late event in pancreatic tumorigenesis	26
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Pitfalls in machine learning‐based assessment of tumor‐infiltrating lymphocytes in breast cancer: A report of the International Immuno‐Oncology Biomarker Working Group on Breast Cancer	25
BMP signalling in colorectal cancer: losing the yin to WNTs yang	25
Transcriptomics and proteomics reveal distinct biology for lymph node metastases and tumour deposits in colorectal cancer	24
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Integrated molecular characterization of esophageal basaloid squamous cell carcinoma: a subtype with distinct RNA expression pattern and immune characteristics, but no specific genetic muta	23
PCDHGC3 hypermethylation as a potential biomarker of intestinal neuroendocrine carcinomas	23
The earliest events in BRAF‐mutant colorectal cancer: exome sequencing of sessile serrated lesions with a tiny focus dysplasia or cancer reveals recurring mutations in two distinct p	23
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Deep learning based on hematoxylin–eosin staining outperforms immunohistochemistry in predicting molecular subtypes of gastric adenocarcinoma	23
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Lineage tracing in human tissues	22
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Canonical Kaiso target genes define a functional signature that associates with breast cancer survival and the invasive lobular carcinoma histological type	22
Increased expression of phosphodiesterase 4 in activated hepatic stellate cells promotes cytoskeleton remodeling and cell migration	21
PIK3CA mutation subtype delineates distinct immune profiles in gastric carcinoma	21
Copy‐number intratumor heterogeneity increases the risk of relapse in chemotherapy‐naive stage II colon cancer	21
Multiregion exome sequencing indicates a monoclonal origin of esophageal spindle‐cell squamous cell carcinoma	21
Tumor immune microenvironment alterations associated with progression in human intraductal papillary mucinous neoplasms	21
Random forest modelling demonstrates microglial and protein misfolding features to be key phenotypic markers in C9orf72 ‐AL	21
Long‐term treatment of cancer‐prone germline PTEN mutant mice with low‐dose rapamycin extends lifespan and delays tumour development	20
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Liver insulin‐like growth factor‐1 mediates effects of low‐intensity vibration on wound healing in diabetic mice	19
DNA methylation patterns are influenced by Pax3 ::	19
Caspase activation in tumour‐infiltrating lymphocytes is associated with lymph node metastasis in oral squamous cell carcinoma	19
Macrophages producing chondroitin sulfate proteoglycan‐4 induce neuro‐cardiac junction impairment in Duchenne muscular dystrophy	19

C1GALT1 expression predicts poor survival in osteosarcoma and is crucial for ABCC1 transporter‐mediated doxorubicin re	18
APC‐related multiple salivary gland lesions: spatial transcriptomic analysis reveals progressive WNT activation	18
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Divergent evolution of metachronous follicular lymphoma and extranodal marginal zone lymphoma of mucosa‐associated lymphoid tissue from a common precursor	18
Histone deacetylase 6 inhibition attenuates pathological cardiac hypertrophy by promoting autophagy through MAP1LC3B ubiquitination	18
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Assessing spatial sequencing and imaging approaches to capture the molecular and pathological heterogeneity of archived cancer tissues	18
Anti‐CD40L therapy prevents the formation of precursor lesions to gastric B‐cell MALT lymphoma in a mouse model	18
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Correction to ‘Dual inhibition of the endothelin and angiotensin receptor ameliorates renal and inner ear pathologies in Alport mice’	18
Cell division‐dependent dissemination following E‐cadherin loss underlies initiation of diffuse‐type gastric cancer	18
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Re‐interpreting tumour behaviour and the tumour microenvironment as normal responses to tissue disorganisation	18
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Defining the first bona fide cell model for SMARCA4‐deficient, undifferentiated tumor	18
Expanding the clinicopathologic spectrum and genomic landscape of tumors with SMARCA2/4::CREM fusions	17
Revisionist history uncovers a simplified molecular‐based classification of differentiated thyroid cancer	17
Unleashing the potential of AI for pathology: challenges and recommendations	17
Mutation profiling in differential diagnosis between TdT ‐positive high‐grade/large B‐cell lymphoma and B‐lymphoblastic leukaemia/lymphoma	17
Human colonic organoids for understanding early events of familial adenomatous polyposis pathogenesis	17
Differential involvement of LUBAC‐mediated linear ubiquitination in intestinal epithelial cells and macrophages during intestinal inflammation	16
Spasmolytic polypeptide‐expressing metaplasia (SPEM) cell lineages can be an origin of gastric cancer	16
Pancancer cytotoxic T‐cell trapping: are neutrophil extracellular traps a viable biomarker for immunotherapy response?†	16
Proteomic profiling identifies novel diagnostic biomarkers and molecular subtypes for mucinous tubular and spindle cell carcinoma of the kidney	16
Fusion with type 2 macrophages induces melanoma cell heterogeneity that potentiates immunological escape from cytotoxic T lymphocytes	16
Genetic alterations during the neoplastic cascade towards cholangiocarcinoma in primary sclerosing cholangitis	16
Transcriptomic profiles of myxofibrosarcoma and undifferentiated pleomorphic sarcoma correlate with clinical and genomic features	16
PI3 expression predicts recurrence after chemotherapy with DNA‐damaging drugs in gastric cancer	15
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The state of the art for artificial intelligence in lung digital pathology	15
The importance of tumor microenvironment modulations in the progression of pancreatic intraductal papillary mucinous neoplasms†	15
Cdt1 overexpression drives colorectal carcinogenesis through origin overlicensing and DNA damage	15
Indoleamine 2,3‐dioxygenase (IDO)‐1 and IDO‐2 activity and severe course of COVID‐19	14
Genomic analysis defines distinct pancreatic and neuronal subtypes of lung carcinoid	14
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Stress testing deep learning models for prostate cancer detection on biopsies and surgical specimens	14
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Immune‐related gene expression signatures: a step forward in the stratification of patients with ovarian clear cell carcinoma †	14
‘Experimentally‐induced anti‐myeloperoxidase vasculitis does not require properdin, MASP‐2 or bone marrow‐derived C5’	14
Jeremy Jass Prize for Research Excellence in Pathology 2021	13
Tracing metastatic spread in pediatric solid tumors using copy number and targeted deep sequencing	13
Integrative analysis of transcriptomic and metabolomic profiles reveals abnormal phosphatidylinositol metabolism in follicles from endometriosis‐associated infertility patients	13
Evidence for etiologic field changes in tongue distant from tumor in patients with squamous cell carcinoma of the oral tongue	13
The spectrum and significance of secondary (co‐occurring) genetic alterations in sarcomas: the hallmarks of sarcomagenesis	13
Consensus molecular subtype transition during progression of colorectal cancer	13
Local factor H production by human choroidal endothelial cells mitigates complement deposition: implications for macular degeneration	13
Clinical significance of pancreatic ductal metaplasia	13
Metformin confers sensitisation to syrosingopine in multiple myeloma cells by metabolic blockage and inhibition of protein synthesis	13
Application of digital pathology‐based advanced analytics of tumour microenvironment organisation to predict prognosis and therapeutic response	13
Tumor‐infiltrating lymphocytes‐based subtypes and genomic characteristics of EBV‐associated lymphoepithelioma‐like carcinoma	12
CD27 / CD70 pathway activation in primary cutaneous CD4 + small/med	12
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UPK3A+ umbrella cell damage mediated by TLR3–NR2F6 triggers programmed destruction of urothelium in Hunner‐type interstitial cystitis/painful bladder syndrome	12
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Interaction of the tumor suppressor SMAD4 and WNT signaling in progression to oral squamous cell carcinoma	12
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Clonal dynamics of chronic myelomonocytic leukemia progression: paired‐sample comparison	12
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Nuclear pCHK1 as a potential biomarker of increased sensitivity to ATR inhibition	11
Lack of EGFR catalytic activity in hepatocytes improves liver regeneration following DDC‐induced cholestatic injury by promoting a pro‐restorative inflammatory response	11
Fibrinogen Aα‐chain amyloidosis outbreaks in Japanese squirrels (Sciurus lis): a potential disease model	11
Disorganisation of basement membrane zone architecture impairs melanocyte residence in vitiligo	11
Contribution of alterations in peritubular capillary density and microcirculation to the progression of tubular injury and kidney fibrosis	11
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Validated biomarker assays confirm that ARID1A loss is confounded with MMR deficiency,	11
The phospholipid flippase ATP9A enhances macropinocytosis to promote nutrient starvation tolerance in hepatocellular carcinoma	11
Enhanced diagnostic potential of CSPG4 in melanoma and nevi: a comparative study with PRAME ,	11
Extracellular vesicles arising from apoptosis: forms, functions, and applications	11
Downregulation of HDAC9 by the ketone metabolite β‐hydroxybutyrate suppresses vascular calcification	11
Computational pathology in cancer diagnosis, prognosis, and prediction – present day and prospects	11
Oronasal mucosal melanoma is defined by two transcriptional subtypes in humans and dogs with implications for diagnosis and therapy	10
Ferrostatin‐1 modulates dysregulated kidney lipids in acute kidney injury	10
Role of Toll‐like receptor 4 in intravascular hemolysis‐mediated injury	10
Chemokine profiling of melanoma–macrophage crosstalk identifies CCL8 and CCL15 as prognostic facto	10
Discoidin domain receptor 2 signaling through PIK3C2α in fibroblasts promotes lung fibrosis	10
Afadin loss induces breast cancer metastasis through destabilisation of E‐cadherin to F‐actin linkage	10
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Super resolution of pathology images with hierarchical feature integration and local image patterns	10
NEIL3 promotes hepatoma epithelial–mesenchymal transition by activating the BRAF/MEK/ERK/TWIST signaling pathway	10
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Peak density of immature nerve cells occurs with high‐grade dysplasia in intraductal papillary mucinous neoplasms of the pancreas	10
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A Tc1‐ and Th1‐T‐lymphocyte‐rich tumor microenvironment is a hallmark of MSI colorectal cancer	10
Comprehensive splicing analysis of the alternatively spliced CHEK2 exons 8 and 10 reveals three en	10
Computer‐extracted features of nuclear morphology in hematoxylin and eosin images distinguish stage II and IV colon tumors	10
Cell state dynamics during early stages of serous endometrial carcinoma	10
Muramyl dipeptide alleviates estrogen deficiency‐induced osteoporosis through canonical Wnt signaling	10
Periostin‐IHH feedforward loop promotes hepatocellular carcinoma development by enhancing hepatic fibrosis and tumor cell proliferation	10
Reducing the risks of nuclear war – the role of health professionals	10
Dual inhibition of the endothelin and angiotensin receptor ameliorates renal and inner ear pathologies in Alport mice	10
Disseminated cancer cells detected by immunocytology in lymph nodes of NSCLC patients are highly prognostic and undergo parallel molecular evolution	10