Journal of Pathology

Article	Citations
Intravenous iron treatment fuels chronic kidney disease‐induced arterial media calcification in rats	89
The association between the tumor immune microenvironments and clinical outcome in low‐grade, early‐stage endometrial cancer patients	80
Integration of peripheral blood‐ and tissue‐based biomarkers of response to immune checkpoint blockade in urothelial carcinoma	79
High‐resolution and quantitative spatial analysis reveal intra‐ductal phenotypic and functional diversification in pancreatic cancer	79
Breathing in danger: how particulate matter pollution is putting the public at risk of lung cancer†	70
Novel prognostication biomarker adipophilin reveals a metabolic shift in uveal melanoma and new therapeutic opportunities	66
CXCR4 mediates leukemic cell migration and survival in the testicular microenvironment	63
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Ovarian high‐grade serous carcinoma cells with low SMARCA4 expression and high SMARCA2 expression contribute to platinum resistance	58
‘Know thyself’ – host factors influencing cancer response to immune checkpoint inhibitors	56
Probing the tumorigenic potential of genetic interactions reconstituted in murine fallopian tube organoids	53
Spatial profiling of ANO7 in prostate tissue: links to AR‐signalling‐associated lipid metabolism and inflammation	52
A new FGF15/19‐mediated gut‐to‐heart axis controls cardiac hypertrophy	51
Escape from senescence: molecular basis and therapeutic ramifications	48
Artificial intelligence to identify genetic alterations in conventional histopathology	47
Presence of Tim3+ and PD‐1+CD8+T cells identifies microsatellite stable colorectal carcinomas with immune exhaustion and di	45
Collagen VI promotes recovery from colitis by inducing lymphangiogenesis and drainage of inflammatory cells	43
Identification of tumour‐infiltrating myeloid subsets associated with overall survival in lung squamous cell carcinoma	42
Integrating computational pathology and proteomics to address tumor heterogeneity	42
Genomic features of Helicobacter pylori‐naïve diffuse‐type gastric cancer	42
CRISPR–Cas9 screening identifies the role of FER as a tumor suppressor	42
The E2F1–HOXB9/PBX2–CDK6 axis drives gastric tumorigenesis and serves as a therapeutic target in gastric cancer	39
Pseudobudding: ruptured glands do not represent true tumor buds	38
Human scattered tubular cells represent a heterogeneous population of glycolytic dedifferentiated proximal tubule cells	37
Silencing GRHL3 promotes multiple organ distant metastasis of lung squamous cell carcinoma cells by enhancing SOX2 stability via SIRT1	36

In high‐grade ovarian carcinoma, platinum‐sensitive tumor recurrence and acquired‐resistance derive from quiescent residual cancer cells that overexpress CRYAB, CEACAM6, and	35
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Platelet C3G protects from liver fibrosis, while enhancing tumor growth through regulation of the immune response	34
Field cancerization in breast cancer	33
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Characterisation of an enhanced preclinical model of experimental MPO‐ANCA autoimmune vasculitis	32
Prediction of coexisting invasive carcinoma on ductal carcinoma in situ (DCIS) lesions by mass spectrometry imaging	31
Development of a multi‐scanner facility for data acquisition for digital pathology artificial intelligence	31
Integrative analysis of genomic and transcriptomic data of normal, tumour, and co‐occurring leukoplakia tissue triads drawn from patients with gingivobuccal oral cancer identifies signatures of tumour	29
Adrenomedullin2 stimulates progression of thyroid cancer in mice and humans under nutrient excess conditions	29
On the origin of gastric tumours: analysis of a case with intramucosal gastric carcinoma and oxyntic gland adenoma	29
Genetic and epigenetic alterations in precursor lesions of endometrial endometrioid carcinoma	29
Primary thyroid B‐cell lymphoma: molecular insights into its clonal evolution and relapse	28
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Minigene‐based splicing analysis and ACMG/AMP‐based tentative classification of 56 ATM variants	27
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Downregulated BMP–Smad1/5/8 signaling causes emphysema via dysfunction of alveolar type II epithelial cells	27
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Tumor immune microenvironment alterations associated with progression in human intraductal papillary mucinous neoplasms	26
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Copy‐number intratumor heterogeneity increases the risk of relapse in chemotherapy‐naive stage II colon cancer	25
Random forest modelling demonstrates microglial and protein misfolding features to be key phenotypic markers in C9orf72‐ALS	25
BMP signalling in colorectal cancer: losing the yin to WNTs yang	25
Lineage tracing in human tissues	25
Deep learning based on hematoxylin–eosin staining outperforms immunohistochemistry in predicting molecular subtypes of gastric adenocarcinoma	25
Canonical Kaiso target genes define a functional signature that associates with breast cancer survival and the invasive lobular carcinoma histological type	24
Integrated molecular characterization of esophageal basaloid squamous cell carcinoma: a subtype with distinct RNA expression pattern and immune characteristics, but no specific genetic muta	24
PCDHGC3 hypermethylation as a potential biomarker of intestinal neuroendocrine carcinomas	24
Somatic loss ofATMis a late event in pancreatic tumorigenesis	24
Increased expression of phosphodiesterase 4 in activated hepatic stellate cells promotes cytoskeleton remodeling and cell migration	23
Transcriptomics and proteomics reveal distinct biology for lymph node metastases and tumour deposits in colorectal cancer	23
The earliest events in BRAF‐mutant colorectal cancer: exome sequencing of sessile serrated lesions with a tiny focus dysplasia or cancer reveals recurring mutations in two distinct p	23
PIK3CA mutation subtype delineates distinct immune profiles in gastric carcinoma	22
Genomic analysis and preclinical xenograft model development identify potential therapeutic targets for MYOD1‐mutant soft‐tissue sarcoma of childhood	22
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Pitfalls in machine learning‐based assessment of tumor‐infiltrating lymphocytes in breast cancer: A report of the International Immuno‐Oncology Biomarker Working Group on Breast Cancer	22
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Assessing spatial sequencing and imaging approaches to capture the molecular and pathological heterogeneity of archived cancer tissues	21
Cell division‐dependent dissemination following E‐cadherin loss underlies initiation of diffuse‐type gastric cancer	21
Multiregion exome sequencing indicates a monoclonal origin of esophageal spindle‐cell squamous cell carcinoma	21
C1GALT1 expression predicts poor survival in osteosarcoma and is crucial for ABCC1 transporter‐mediated doxorubicin resistance	21
Caspase activation in tumour‐infiltrating lymphocytes is associated with lymph node metastasis in oral squamous cell carcinoma	20
DNA methylation patterns are influenced by Pax3::Foxo1 expression and developmental lineage in rhabdomyosarcoma tumours forming in genetically engineered	20
Macrophages producing chondroitin sulfate proteoglycan‐4 induce neuro‐cardiac junction impairment in Duchenne muscular dystrophy	20
Liver insulin‐like growth factor‐1 mediates effects of low‐intensity vibration on wound healing in diabetic mice	20
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Histone deacetylase 6 inhibition attenuates pathological cardiac hypertrophy by promoting autophagy through MAP1LC3B ubiquitination	19

Long‐term treatment of cancer‐prone germline PTEN mutant mice with low‐dose rapamycin extends lifespan and delays tumour development	19
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Divergent evolution of metachronous follicular lymphoma and extranodal marginal zone lymphoma of mucosa‐associated lymphoid tissue from a common precursor	18
Differential involvement of LUBAC‐mediated linear ubiquitination in intestinal epithelial cells and macrophages during intestinal inflammation	18
Transcriptomic profiles of myxofibrosarcoma and undifferentiated pleomorphic sarcoma correlate with clinical and genomic features	18
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Re‐interpreting tumour behaviour and the tumour microenvironment as normal responses to tissue disorganisation	18
Expanding the clinicopathologic spectrum and genomic landscape of tumors with SMARCA2/4::CREM fusions	18
Spasmolytic polypeptide‐expressing metaplasia (SPEM) cell lineages can be an origin of gastric cancer	18
Correction to ‘Dual inhibition of the endothelin and angiotensin receptor ameliorates renal and inner ear pathologies in Alport mice’	18
Anti‐CD40L therapy prevents the formation of precursor lesions to gastric B‐cell MALT lymphoma in a mouse model	18
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Defining the first bona fide cell model for SMARCA4‐deficient, undifferentiated tumor	18
Fusion with type 2 macrophages induces melanoma cell heterogeneity that potentiates immunological escape from cytotoxic T lymphocytes	18
The state of the art for artificial intelligence in lung digital pathology	18
Proteomic profiling identifies novel diagnostic biomarkers and molecular subtypes for mucinous tubular and spindle cell carcinoma of the kidney	17
Pancancer cytotoxic T‐cell trapping: are neutrophil extracellular traps a viable biomarker for immunotherapy response?†	17
Unleashing the potential of AI for pathology: challenges and recommendations	17
Cdt1 overexpression drives colorectal carcinogenesis through origin overlicensing and DNA damage	17
Human colonic organoids for understanding early events of familial adenomatous polyposis pathogenesis	16
‘Experimentally‐induced anti‐myeloperoxidase vasculitis does not require properdin, MASP‐2 or bone marrow‐derived C5’	16
Genetic alterations during the neoplastic cascade towards cholangiocarcinoma in primary sclerosing cholangitis	16
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Jeremy Jass Prize for Research Excellence in Pathology 2021	16
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The spectrum and significance of secondary (co‐occurring) genetic alterations in sarcomas: the hallmarks of sarcomagenesis	15
Clinical significance of pancreatic ductal metaplasia	15
Consensus molecular subtype transition during progression of colorectal cancer	15
Local factor H production by human choroidal endothelial cells mitigates complement deposition: implications for macular degeneration	15
Evidence for etiologic field changes in tongue distant from tumor in patients with squamous cell carcinoma of the oral tongue	15
Metformin confers sensitisation to syrosingopine in multiple myeloma cells by metabolic blockage and inhibition of protein synthesis	15
Integrative analysis of transcriptomic and metabolomic profiles reveals abnormal phosphatidylinositol metabolism in follicles from endometriosis‐associated infertility patients	15
PI3 expression predicts recurrence after chemotherapy with DNA‐damaging drugs in gastric cancer	14
UPK3A+ umbrella cell damage mediated by TLR3–NR2F6 triggers programmed destruction of urothelium in Hunner‐type interstitial cystitis/painful bladder syndrome	14
Stress testing deep learning models for prostate cancer detection on biopsies and surgical specimens	14
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Nuclear pCHK1 as a potential biomarker of increased sensitivity to ATR inhibition	14
Optical genome mapping identifies a germline retrotransposon insertion in SMARCB1 in two siblings with atypical teratoid rhabdoid tumors	14
Genomic analysis defines distinct pancreatic and neuronal subtypes of lung carcinoid	14
Application of digital pathology‐based advanced analytics of tumour microenvironment organisation to predict prognosis and therapeutic response	14
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Tumor‐infiltrating lymphocytes‐based subtypes and genomic characteristics of EBV‐associated lymphoepithelioma‐like carcinoma	14
RAF1–MEK/ERK pathway‐dependent ARL4C expression promotes ameloblastoma cell proliferation and osteoclast formation	14
Immune‐related gene expression signatures: a step forward in the stratification of patients with ovarian clear cell carcinoma†	14
Lack of EGFR catalytic activity in hepatocytes improves liver regeneration following DDC‐induced cholestatic injury by promoting a pro‐restorative inflammatory response	14
Abstracts	14
Indoleamine 2,3‐dioxygenase (IDO)‐1 and IDO‐2 activity and severe course of COVID‐19	14
Interaction of the tumor suppressor SMAD4 and WNT signaling in progression to oral squamous cell carcinoma	13
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Extracellular vesicles arising from apoptosis: forms, functions, and applications	13
Clonal dynamics of chronic myelomonocytic leukemia progression: paired‐sample comparison	13
Disordered farnesoid X receptor signaling is associated with liver carcinogenesis in Abcb11‐deficient mice	13
Computational pathology in cancer diagnosis, prognosis, and prediction – present day and prospects	13
Contribution of alterations in peritubular capillary density and microcirculation to the progression of tubular injury and kidney fibrosis	13
Brg1 is required to maintain colorectal cancer stem cells	13
CD27/CD70 pathway activation in primary cutaneous CD4+ small/medium T‐cell lymphoproliferative disorder	13
Fibrinogen Aα‐chain amyloidosis outbreaks in Japanese squirrels (Sciurus lis): a potential disease model	13
FOXL2 in adult‐type granulosa cell tumour of the ovary: oncogene or tumour suppressor gene?	12
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Dual inhibition of the endothelin and angiotensin receptor ameliorates renal and inner ear pathologies in Alport mice	12
FOXL2C134W: much ado about something!†	12
Validated biomarker assays confirm that ARID1A loss is confounded with MMR deficiency, CD8+ TIL infiltration, and provides no independent prognostic value i	12
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NEIL3 promotes hepatoma epithelial–mesenchymal transition by activating the BRAF/MEK/ERK/TWIST signaling pathway	12
Role of Toll‐like receptor 4 in intravascular hemolysis‐mediated injury	12
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Ferrostatin‐1 modulates dysregulated kidney lipids in acute kidney injury	12
A Tc1‐ and Th1‐T‐lymphocyte‐rich tumor microenvironment is a hallmark of MSI colorectal cancer	12
Molecular genetic evidence supporting diverse histogenic origins of germ cell tumors	11
Downregulation of HDAC9 by the ketone metabolite β‐hydroxybutyrate suppresses vascular calcification	11
The phospholipid flippase ATP9A enhances macropinocytosis to promote nutrient starvation tolerance in hepatocellular carcinoma	11
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Disorganisation of basement membrane zone architecture impairs melanocyte residence in vitiligo	11
Disseminated cancer cells detected by immunocytology in lymph nodes of NSCLC patients are highly prognostic and undergo parallel molecular evolution	11
Comprehensive splicing analysis of the alternatively spliced CHEK2 exons 8 and 10 reveals three enhancer/silencer‐rich regions and 38 spliceogenic variants	11
Computer‐extracted features of nuclear morphology in hematoxylin and eosin images distinguish stage II and IV colon tumors	11
Oronasal mucosal melanoma is defined by two transcriptional subtypes in humans and dogs with implications for diagnosis and therapy	11
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Activated immune infiltrates expand opportunities for targeted therapy in p53‐abnormal endometrial carcinoma	10
Oncostatin M is overexpressed in NASH‐related hepatocellular carcinoma and promotes cancer cell invasiveness and angiogenesis	10
Afadin loss induces breast cancer metastasis through destabilisation of E‐cadherin to F‐actin linkage	10
Peak density of immature nerve cells occurs with high‐grade dysplasia in intraductal papillary mucinous neoplasms of the pancreas	10
Reducing the risks of nuclear war – the role of health professionals	10
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Distinct genomic landscapes in radiation‐associated angiosarcoma compared with other radiation‐associated sarcoma histologies	10
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P2X4 purinergic receptors offer a therapeutic target for aggressive prostate cancer	10
TP53 disruptive mutation predicts platinum‐based chemotherapy and PD‐1/PD‐L1 blockade response in urothelial carcinoma	10