OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Periodontal Research is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
	269
Six miRNA expressions in the saliva of smokers and non‐smokers with periodontal disease	88
Periodontal Clinical Practice: The Past, the Present, the Future	79
Does Computer‐Assisted Surgery Improve the Accuracy of Immediate Implant Placement? A Systematic Review and Network Meta‐Analysis	69
Artificial Intelligence in Periodontology: A Systematic Review	65
Effect of low‐intensity pulsed ultrasound on the mineralization of force‐treated cementoblasts and orthodontically induced inflammatory root resorption via the Lamin A/C‐Yes associated protein axis	56
Ability of gingival crevicular fluid volume, E‐cadherin, and total antioxidant capacity levels for predicting outcomes of nonsurgical periodontal therapy for periodontitis patients	53
Early Cigarette Smoking Onset Increases Edentulism Risk	50
Leptin‐deficient ob/ob mice exhibit periodontitis phenotype and altered oral microbiome	43
The efficacy of adjunctive periodontal therapies during supportive periodontal care in patients with residual pockets. A systematic review and meta‐analysis	42
The association between vitamin D binding protein levels and periodontal status: A systematic review	38
Soft Tissue Augmentation Around Dental Implants: Techniques, Timing, and Comparative Efficacy—A Systematic Review and Network Meta‐Analysis	33
Dietary patterns and periodontitis: A systematic review	33
The periodontal ligament, temperature‐sensitive ion channels TRPV1–4, and the mechanosensitive ion channels Piezo1 and 2: A Nobel connection	31
3‐methyl‐1H‐indol‐1‐yl dimethylcarbamodithioate attenuates periodontitis through targeting MAPK signaling pathway‐regulated mitochondrial function	30
Effects of periodontal cells‐derived extracellular vesicles on mesenchymal stromal cell function	30
High‐Frequency Ultrasound for Detecting Periodontal Inflammation: A Preclinical Diagnostic Accuracy Study	29
Genetic analysis of impaired healing responses after periodontal therapy in type 2 diabetes: Clinical and in vivo studies	29
Periodontitis causally affects the brain cortical structure: A Mendelian randomization study	28
Cover Image	28
Glucagon‐Like Peptide 1 Receptor Agonists ( GLP ‐ 1RAs ) Improve Periodontal and Peri‐Implant Heal	27
Semaphorin 3A protects against alveolar bone loss during orthodontic tooth movement in mice with periodontitis	26
Role of ferroptosis in periodontitis: An animal study in rats	25
Cover Image	24
Artificial Intelligence in Periodontology: The Past, the Present, the Future	24

Differential expression of FSTL1 and its correlation with the pathological process of periodontitis	23
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Colitis induced by dextran sulphate sodium causes histopathological and immunological changes in the periodontal tissues of Wistar rats	23
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Gingival tissue samples from periodontitis patients demonstrate epithelial–mesenchymal transition phenotype	22
TRPV1 Promotes Periodontitis Tissue Inflammation and Oxidative Damage by Regulating STAT3 Signaling Pathway	22
Proliferative effect of cannabidiol in human gingival fibroblasts via the mitogen‐activated extracellular signal‐regulated kinase (MEK) 1/2	22
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Periodontitis and risk of mortality in patients with chronic kidney disease: A systematic review with meta‐analysis	21
Hypoxia dissociates HDAC6/FOXO1 complex and aggregates them into nucleus to regulate autophagy and osteogenic differentiation	21
Journal of Periodontal Research—the past, the present, the future: The legacy of periodontology is here!	20
Use of ultrasound imaging for assessment of the periodontium: A systematic review	20
Immunohistochemical analysis with apoptosis and autophagy markers in periodontitis and peri‐implantitis: Clinical comparative study	20
Submucosal Microbiome in Peri‐Implantitis: A Comparative Metagenomic Analysis	19
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Metagenomic Insights Into the Subgingival Microbiome in Periodontal Health and Different Grades of Periodontitis	19
Expression profile analysis of long noncoding RNA and messenger RNA during mouse cementoblast mineralization	18
Transcriptome Analysis of Porphyromonas gingivalis Lipopolysaccharide‐Induced Early Gene Expression in Human Gingival Keratinocytes	18
Increased expression of angiopoietin‐like protein 4 regulates matrix metalloproteinase‐13 expression in Porphyromonas gingivalis lipopolysaccharides‐stimulated gingival fibroblasts and ligature	18
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Issue Information	18
A Novel Gene DUSP8 Missense Mutation Causes Nonsyndromic Hereditary Gingival Fibromatosis by Dysre	18
Effects of vitamin K2 administration on guided bone regeneration in diabetic rats	17
Biomarker panel discriminates diabetics with and without periodontitis pre‐ and post‐therapy	17
RETRACTION: I. Yamawaki, Y. Taguchi, S. Komasa, A. Tanaka, and M. Umeda, “Effects of Glucose Concentration on Osteogenic Differentiation of Type II D	17
Chronic hyperglycemia reduces the expression of intercellular adhesion molecules and increases intercellular hyperpermeability in the periodontal epithelium	16
Tamoxifen improves homeostasis in the peri‐implant bone remodeling of osseointegrated titanium implants	16
Periodontitis Exacerbates Colorectal Cancer by Altering Gut Microbiota–Derived Metabolomics in Mice	16
Study on the effect of periodontitis on renal tissue in atherosclerotic mice	16
Role of sodium‐dependent vitamin C transporter 2 in human periodontal ligament fibroblasts	16
Relationship between periodontal status and dyslipidemia in patients with type 2 diabetic nephropathy and chronic periodontitis: A cross‐sectional study	16
Dipyridamole Attenuates Experimental Periodontitis by Regulating M1 Macrophage Polarization via PKA/PKG Pathways	15
Cross‐sectional analysis of the association of periodontitis with carotid intima media thickness and atherosclerotic plaque in the Hamburg City health study	15
Levels of matrix metalloproteinase‐1 ( MMP ‐1), MMP ‐2, MMP	15
Augmented and Virtual Reality in Dental Medicine Updated: A Systematic Review and Meta‐Analysis	15
Cardiovascular Disease Detection in Dental Settings—Development and External Validation of a Nomogram ( PerioCARD )	15
Does smoking influence tryptophan metabolism in periodontal inflammation? A cross‐sectional study	14
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Bone Grafts: Everything You Need to Know	14
Epigenetic Regulation in the Pathogenesis of Periodontitis	14
Effects of amoxicillin and metronidazole as an adjunct to scaling and root planing on glycemic control in patients with periodontitis and type 2 diabetes: A short‐term randomized controlled trial	14
Relationship between oral microbiota and colorectal cancer: A systematic review	14
New putative periodontopathogens and periodontal health‐associated species: A systematic review and meta‐analysis	14
Association between Mediterranean diet and periodontitis among US adults: The mediating roles of obesity indicators	14
Effect of lentivirus‐mediatedBMP2from autologous tooth on the proliferative and osteogenic capacity of human periodontal ligament cells	14
Insulin resistance and periodontitis: Mediation by blood pressure	14
Comparison of oxidative stress markers in the saliva, gingival crevicular fluid, and serum samples of pregnant women with gestational diabetes and healthy pregnant women	14
Issue Information	14
Association between asthma and periodontitis: A case–control analysis of risk factors, related medications, and allergic responses	14
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Oxytocin alleviates periodontitis in adult rats	14
Hepatocyte growth factor is protective in early stage but bone‐destructive in late stage of experimental periodontitis	13
Loss of β‐catenin causes cementum hypoplasia by hampering cementogenic differentiation of Axin2‐expressing cells	13
Effect of photobiomodulation with different wavelengths on periodontal repair in non‐hyperglycemic and hyperglycemic rats	13
Recombinant irisin enhances the extracellular matrix formation, remodeling potential, and differentiation of human periodontal ligament cells cultured in 3D	13
Hyperlipidemia impairs bone regeneration of closed bone defects and tooth extraction wounds in mice	13
Issue Information	13
Multiomics Comparison of Proline‐Rich Peptide‐Enhanced Hyaluronic Acid Gels Versus Conventional Regenerative Materials: An Early Wound‐Healing Model	13
Association of individual and combined exposures of 10 metals with periodontitis: Results from a large population‐based study	13
The influence of different extraction indications on the morphological changes in the maxillary sinus: A retrospective cohort study	13
Issue Information	13
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Inflammation Affects the Osteogenic Differentiation of Aged Periodontal Ligament Cells via NF‐κB/FOXO3a/c‐JUN Signalling	13
Effectiveness of novel oral hygiene instruction avoiding inattentional blindness using an application for unique plaque control record calculation: A randomized clinical trial	13
Periodontal pathogen Fusobacterium nucleatum infection accelerates hepatic steatosis in high‐fat diet‐fed ApoE	13
Microbiome of periodontitis and peri‐implantitis before and after therapy: Long‐read 16S rRNA gene amplicon sequencing	12
Proanthocyanidin enhances the endogenous regeneration of alveolar bone by elevating the autophagy of PDLSCs	12
PGC‐1α attenuates TNF‐α‐induced inflammatory responses in OCCM‐30 cells	12
Treatment Options for the Management of the Postextraction Socket: Report From the First Giuseppe Cardaropoli Foundation Consensus Conference	12
Target Trial Emulation in Observational Research—Strengths, Limitations, and Methodological Considerations	12
Extracellular Vesicles in Gingival Crevicular Fluid as Indicators of Periodontitis and Early Response to Non‐surgical Periodontal Therapy	12
Issue Information	12
The effect of Porphyromonas gingivalis on the gut microbiome of mice in relation to aging	12
Accuracy of aMMP‐8 point‐of‐care test in indicating periodontal treatment outcomes in stage III/IV periodontitis: A 24‐week follow‐up study	12
Gingival tissue antibody gene utilization in aging and periodontitis	12
Autoimmunity and Periodontitis	12
TAM Pathway Receptor Proteins: Differential Expression in Healthy Human Masticatory Mucosa	12
Demystifying the connection between periodontal disease and chronic kidney disease – An umbrella review	12
Multiplexed LC‐MS/MS quantification of salivary RNA modifications in periodontitis	12
Issue Information	11
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Oral‐gut bacterial profiles discriminate between periodontal health and diseases	11
Periodontal Prognosis: The Past, the Present, the Future	11
Periodontal granulation tissue – To remove or not to remove, that is the question	11
METTL3 promotes the osteogenic differentiation of human periodontal ligament cells by increasing YAP activity via IGF2BP1 and YTHDF1‐mediated m⁶	11
New Cover of the Journal of Periodontal Research—The Story Behind	11
Risk of Bias Evaluation of Cross‐Sectional Studies: Adaptation of the Newcastle‐Ottawa Scale	11
Lipotoxicity: The missing link between diabetes and periodontitis?	11
Periodontitis and edentulism as risk indicators for mortality: Results from a prospective cohort study with 20 years of follow‐up	11
Adjunctive use of omega‐3 fatty acids in combination with low‐dose aspirin in periodontitis: Systematic review and meta‐analysis	11
Expression of Wnt signaling agonists and antagonists in periodontitis and healthy subjects, before and after non‐surgical periodontal treatment: A systematic review	11
Development of a classification model and an immune‐related network based on ferroptosis in periodontitis	11
Melatonin promoted osteogenesis of human periodontal ligament cells by regulating mitochondrial functions through the translocase of the outer mitochondrial membrane 20	11
Lipocalin 2, synthesized using a cell‐free protein synthesis system and encapsulated into liposomes, inhibits the adhesion of Porphyromonas gingivalis to human oral epithelial cells	11
Periodontal disease and its association to endothelial dysfunction and clinical changes in limited systemic sclerosis: A case–control study	11
Peri‐implant crevicular fluid and serum levels of soluble ST2 in peri‐implant diseases: A pilot study	11
Selective outcome reporting bias is highly prevalent in randomized clinical trials of nonsurgical periodontal therapy	11
Pyroptosis may play a crucial role in modifications of the immune microenvironment in periodontitis	10
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Enhancement of receptor‐mediated calcium responses by phenytoin through the suppression of calcium excretion in human gingival fibroblasts	10
The impact of Resolvin E1 on bone regeneration in critical‐sized calvarial defects of rat model—A gene expression and micro‐CT analysis	10
A Principled Framework for Mendelian Randomization in Oral Health Research	10
Genetic Susceptibility to Periodontitis	10
Treatment of periodontitis ameliorates the severity and extent of psoriasis—A randomized clinical trial	10
Dysbiotic relationship between arthritis and the oral‐gut microbiome. A critical review	10
LncRNA JHDM1D‐AS1 promotes osteogenic differentiation of periodontal ligament cells by targeting miR‐532‐5p to activate IGF1R signaling	10
Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia	10
Comparison of Micro‐CT and Morphometric Outcomes in a Modified Experimental Rat Model of Periodontitis	10
Cytokine responses of CD4+ T cells and NKT cells to periodontitis‐associated bacteria in individuals with or without periodontitis	10
DNA damage‐inducible transcript 3 deficiency promotes bone resorption in murine periodontitis models	10
High glucose promotes lipopolysaccharide‐induced macrophage pyroptosis through GSDME O‐GlcNAcylation	10
Limosilactobacillus reuteri ‐ Fusobacterium nucleatum Interactions Modu	10
Dipotassium glycyrrhizate and hinokitiol enhance macrophage efferocytosis by regulating recognition, uptake, and metabolism of apoptotic cells in vitro	10
EGF coating of titanium surfaces modulates cytokines in oral mucosal primary cells exposed to TNF‐α	10
Mobile Health to Improve Efficacy of Interdental Brushing Among Periodontitis Patients: A Randomized Clinical Trial	10
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Prevalence and Risk Indicators of Peri‐Implant Diseases and Buccal Soft‐Tissue Dehiscence: A Cross‐Sectional Study From a University‐Based Cohort	9
Dental Implant Rehabilitation Mitigates the Increased Mortality Risk Associated With Tooth Loss: A Population‐Based Study	9
Lip and Oral Cancer, Caries and Other Oral Conditions: Estimates From the 2021 Global Burden of Disease Study and Projections up to 2050	9
BBR affects macrophage polarization via inhibition of NF‐κB pathway to protect against T2DM‐associated periodontitis	9
Macrophage Efferocytosis Controls Tissue Repair via Mitochondrial Dynamics in Diabetic Periodontitis	9
Soluble epoxide hydrolase inhibition impairs triggering receptor expressed on myeloid cells‐1 in periodontal tissue	9
Issue Information	9
The association between Aggregatibacter actinomycetemcomitansJP2 clone and periodontitis: A systematic review and meta‐analysis	9
The First 60 Years of the Journal of Periodontal Research : Celebrating the Transformation of Periodontics Into Periodontology	9
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The role of mitochondrial dysfunction in periodontitis: From mechanisms to therapeutic strategy	9
Cyclosporine A‐induced gingival overgrowth in renal transplant patients accompanied by epithelial‐to‐mesenchymal transition	9
Extracellular adenosine triphosphate induces IDO and IFNγ expression of human periodontal ligament cells through P₂X₇ receptor signaling	9
Expression of matrix metalloproteinase‐3 and ‐10 is up‐regulated in the periodontal tissues of aged mice	9

Risk Factors of Periodontitis: Evidence From Two‐Sample Mendelian Randomization and Meta‐Analysis	9
Asymmetric and symmetric dimethylarginine gingival crevicular fluid levels in periodontitis	9
Regulation of RIP1‐Mediated necroptosis via necrostatin‐1 in periodontitis	9
Salivary E‐cadherin as a biomarker for diagnosis and predicting grade of periodontitis	9
Caspase‐3 and gasdermin E mediate macrophage pyroptosis in periodontitis	9
LiCl‐induced immunomodulatory periodontal regeneration via the activation of the Wnt/β‐catenin signaling pathway	9
Soft‐Tissue Integration of Dental Implants: Formation, Maintenance, and Relevance for Peri‐Implant Health	9
Proteomic Characterization of Grade II Furcation Defects: A Discovery‐Phase Study	9
Oxidative stress‐related biomarkers in chronic periodontitis patients with or without type 2 diabetes: A systematic review and meta‐analysis	9
SIGIRR Inhibits Periodontitis‐Associated Inflammation and Promotes Regeneration by Blocking Sp1 Nuclear Translocation	9
Cannabidiol attenuates periodontal inflammation through inhibiting TLR4/NF‐κB pathway	9
Issue Information	9
Identifying metabolic parameters related to severity and extent of periodontitis in down syndrome patients	8
Performance of three artificial intelligence (AI)‐based large language models in standardized testing; implications for AI‐assisted dental education	8
Reviewers list 2023	8
Exosomal microRNA‐223 from neutrophil‐like cells inhibits osteogenic differentiation of PDLSCs through the cGMP‐PKG signaling pathway	8
Hydrogels in Periodontal and Craniofacial Regeneration: Current Applications and Next‐Generation Biomaterials	8
Circular RNA hsa_circ_0084054 promotes the progression of periodontitis with diabetes via the miR‐508‐3p/PTEN axis	8
Sclerostin deficiency effectively promotes bone morphogenetic protein‐2‐induced ectopic bone formation	8
Timing of Re‐Evaluation After Periodontal Therapy: A Randomized Clinical Trial	8
Diet‐derived circulating antioxidants, periodontitis and dental caries: A Mendelian randomization study	8
Geographic Influence on Subgingival Microbiota in Health and Periodontitis: A Multinational Shotgun Metagenomic Study	8
Complement components C3b and C4b as potential reliable site‐specific diagnostic biomarkers for periodontitis	8
Tartrate‐Resistant Acid Phosphatase‐Positive Cells: Putative Mediators of Peri‐Implant Bone Healing	8
Biomaterials for Reconstructive Treatment of Peri‐Implantitis	8
The role of vitamin D in periodontal health and disease	8
Severe Periodontitis is Associated With Recurrent Cardiovascular Events—A 10‐Year Longitudinal Cohort Study	8
Periodontal ligament cells from patients with treated stable periodontitis: Characterization and osteogenic differentiation potential	8
Peri‐Implant Diseases: The Past, the Present, the Future	8
Tunnel Versus Coronally Advanced Flap for the Treatment of Localized Gingival Recessions: A Randomized Clinical Trial	8
Periodontal ligament‐associated protein‐1 engages in teeth overeruption and periodontal fiber disorder following occlusal hypofunction	8
Association between defect morphology and healing of intrabony defects treated with minimally invasive non‐surgical therapy: A pilot exploratory analysis of two cohorts	8
Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications	7
Soft‐Tissue Phenotype Modification as an Adjunct to the Treatment of Peri‐Implant Mucositis—A Quasi‐Randomized Clinical Trial	7
Histological Outcomes of Root Coverage Procedures: A Systematic Review With Meta‐Analysis	7
Micro‐needling versus acellular dermal matrix in RT1 gingival recession coverage: A randomized clinical trial	7
Durumamide A Inhibits NLRP3 Assembly, Limiting Pro‐Inflammatory Signaling in Human Gingival Fibroblasts	7
Tooth mobility: The missing link?	7
Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications	7
Impaired autophagy flux by lncRNA NEAT1 is critical for inflammation factors production in human periodontal ligament stem cells with nicotine treatment	7
Preventive effects of melatonin on periodontal tissue destruction due to psychological stress in rats with experimentally induced periodontitis	7
Accuracy of Freehand, Static, and Dynamic Computer‐Assisted Implant Placement: A Systematic Review and Meta‐Analysis	7
NLRC5modulates bone metabolism and plays a role in periodontitis	7
Smokeless tobacco and periodontitis: A systematic review with meta‐analysis	7
High glucose impairs human periodontal ligament cells migration through lowered microRNAs 221 and 222	7
Peri‐Implant Soft‐Tissue Phenotype Modification for Refractory Peri‐Implant Mucositis: A 12‐Month Prospective Clinical Study With Ultrasonographic Analysis	7
Effects of mechanical loading on matrix homeostasis and differentiation potential of periodontal ligament cells: A scoping review	7
Extracellular Vesicles From Dental Pulp Cells Promote Osteogenic Differentiation in Periodontal Ligament Cells	7
Characterization of junctional structures in the gingival epithelium as barriers against bacterial invasion	6
Issue Information	6
Elucidation of common molecular diagnostic biomarkers between chronic periodontitis and Parkinson's disease via bioinformatics analyses	6
Preclinical Evaluation of a Poly (Lactic Acid/Caprolactone) Bilayer Membrane and a Carbonate Apatite for Periodontal Regeneration: A Canine One‐Wall Intrabony Defect Model	6
Porphyromonas gingivalis ‐Lipopolysaccharide Induced Gingival Fibroblasts Trained Immunity Sustains Inflammation in Periodontitis	6
Periostin in the relation between periodontal disease and atherosclerotic coronary artery disease: A pilot randomized clinical study	6
Local application of 0.8% hyaluronic acid gel as an adjunct to minimally invasive nonsurgical treatment of periodontal intrabony defects—A randomized clinical trial	6
Issue Information	6
Hormone replacement therapy and periodontitis progression in postmenopausal women: A prospective cohort study	6
Issue Information	6
Integrative Human Genomic and Pharmacological Analyses Identify CACNB4 as a Druggable Target for Periodontitis	6
MZB1 targeted by miR‐185‐5p inhibits the migration of human periodontal ligament cells through NF‐κB signaling and promotes alveolar bone loss	6
Runx2 heterozygosity alters homeostasis of the periodontal complex	6
Burden of severe periodontitis and edentulism in 2021, with projections up to 2050: The Global Burden of Disease 2021 study	6
Molar–Incisor and Generalized Grade C Periodontitis: Distinct Microbiome–Immune Interactions Suggest Divergent Pathogenesis	6
Limosilactobacillus reuteri supernatant attenuates inflammatory responses of human gingival fibroblasts to LPS but not to elevated glucose levels	6
Bidirectional associations between periodontitis and inflammatory bowel disease: A systematic review of longitudinal studies with meta‐analysis and trial sequential analysis	6
A grooved porous hydroxyapatite scaffold induces osteogenic differentiation via regulation of PKA activity by upregulating miR‐129‐5p expression	6
Umbelliferone reduces inflammation and ligature‐induced osteoclastic alveolar bone resorption in mice	6
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5‐FU Weakens Defensive Functions of the Junctional Epithelium	6
Microgravity Exacerbates Periodontitis In Vivo	6
Effect of Connective Tissue Grafts in the Regenerative Treatment of Intrabony Defects: A Systematic Review and Meta‐Regression Analysis	6
Accuracy of Metabolomics in Peri‐Implant Crevicular Fluid for Diagnosis and Prognosis of Peri‐Implantitis	6
Atypical antipsychotics olanzapine and clozapine increase bone loss in female rats with experimental periodontitis	6
An in vitro study into three different PRF preparations for osteogenesis potential	6
Ibero‐Panamerican Federation of Periodontology Delphi study on the trends of periodontology and periodontics by the year 2030. A Latin American consensus	6
Probiotics enhance alveolar bone microarchitecture, intestinal morphology and estradiol levels in osteoporotic animals	6
Differences in maternal subgingival microbiome between preterm and term births: The MOHEPI study	6
Diet Quality as a Mediator Linking Tooth Loss and Cardiovascular Diseases in Older Adults	6
Biological Responses to Biomaterials: Mechanisms and Opportunities for Enhanced Oral Tissue Regeneration	6
Periodontitis exacerbation during pregnancy in mice: Role of macrophage migration inhibitory factor as a key inductor	6
Disease recurrence during supportive therapy following peri‐implantitis treatment: A retrospective study	6
Influence of gender on periodontal outcomes: A retrospective analysis of eight randomized clinical trials	6
Welcome to the new protagonists of the Journal of Periodontal Research: Our Associate Editors and Editorial Board members!	6
Patients' awareness of the association between periodontitis and other diseases: Still a long way to go	5
Porphyromonas gingivalis Outer Membrane Vesicles Promote Gingival Fibroblasts Senescence via IL21R ‐ <	5
Thyrotropin inhibits osteogenic differentiation of human periodontal ligament stem cells	5
Macrophage Phenotype Alterations in Treated Periodontitis Patients Suggest a Pro‐Inflammatory Bias	5
Issue Information	5
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Annual Incidence and Pre‐Treatment Prognostic Factors of Labial Gingival Recessions in Young Orthodontically Treated Patients	5
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Peri‐Implantitis and Soft Tissue Dehiscence in a Turkish Population: Risk Indicators, Diagnostic Parameters and Biomarkers Discovery	5
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Oxidative stress state inhibits exosome secretion of hPDLCs through a specific mechanism mediated by PRMT1	5