Journal of Pharmaceutical Sciences

Article	Citations
Addressing the Cold Reality of mRNA Vaccine Stability	301
A review of Formulations of Commercially Available Antibodies	115
Manufacturing Challenges and Rational Formulation Development for AAV Viral Vectors	110
Delivery of Therapeutics from Layer-by-Layer Electrospun Nanofiber Matrix for Wound Healing: An Update	82
Sodium Alginate as a Pharmaceutical Excipient: Novel Applications of a Well-known Polymer	67
A Graphical Review on the Escalation of Fused Deposition Modeling (FDM) 3D Printing in the Pharmaceutical Field	60
The Ice-Water Interface and Protein Stability: A Review	58
Implementation of a Human Renal Proximal Tubule on a Chip for Nephrotoxicity and Drug Interaction Studies	56
3D Printing of Solid Oral Dosage Forms: Numerous Challenges With Unique Opportunities	52
Fabrication of Mucoadhesive Buccal Films for Local Administration of Ketoprofen and Lidocaine Hydrochloride by Combining Fused Deposition Modeling and Inkjet Printing	51
Nitrosamine Contamination in Pharmaceuticals: Threat, Impact, and Control	51
The Past, Present and Future of Intestinal In Vitro Cell Systems for Drug Absorption Studies	50
Oxidation and Deamidation of Monoclonal Antibody Products: Potential Impact on Stability, Biological Activity, and Efficacy	49
Coated Lipidic Nanoparticles as a New Strategy for Enhancing Nose-to-Brain Delivery of a Hydrophilic Drug Molecule	49
Rapid Polysorbate 80 Degradation by Liver Carboxylesterase in a Monoclonal Antibody Formulated Drug Substance at Early Stage Development	49
Predicting With Confidence: Using Conformal Prediction in Drug Discovery	49
Binder-Jet 3D Printing of Indomethacin-laden Pharmaceutical Dosage Forms	49
Cyclodextrins in Parenteral Formulations	48
The Storage and In-Use Stability of mRNA Vaccines and Therapeutics: Not A Cold Case	44
Selective Laser Sintering 3-Dimensional Printing as a Single Step Process to Prepare Amorphous Solid Dispersion Dosage Forms for Improved Solubility and Dissolution Rate	44
Freeze-Drying of Pharmaceutical and Nutraceutical Nanoparticles: The Effects of Formulation and Technique Parameters on Nanoparticles Characteristics	41
Intradermal Implantable PLGA Microneedles for Etonogestrel Sustained Release	41
How can Electrospinning Further Service Well for Pharmaceutical Researches?	40
The Science is There: Key Considerations for Stabilizing Viral Vector-Based Covid-19 Vaccines	40
Boric Acid, a Lewis Acid With Unique and Unusual Properties: Formulation Implications	39

Capsaicin Loaded Solid SNEDDS for Enhanced Bioavailability and Anticancer Activity: In-Vitro, In-Silico, and In-Vivo Characterization	39
Three-Dimensional Spheroids With Primary Human Liver Cells and Differential Roles of Kupffer Cells in Drug-Induced Liver Injury	39
Engineering Stability, Viscosity, and Immunogenicity of Antibodies by Computational Design	38
Comprehensive Size Distribution and Composition Analysis of Adeno-Associated Virus Vector by Multiwavelength Sedimentation Velocity Analytical Ultracentrifugation	37
Novel Chitosan-Coated Niosomal Formulation for Improved Management of Bacterial Conjunctivitis: A Highly Permeable and Efficient Ocular Nanocarrier for Azithromycin	37
Development of a Minimal Physiologically-Based Pharmacokinetic Model to Simulate Lung Exposure in Humans Following Oral Administration of Ivermectin for COVID-19 Drug Repurposing	37
Perspectives About Self-Immolative Drug Delivery Systems	36
Primary Human Hepatocyte Spheroid Model as a 3D In Vitro Platform for Metabolism Studies	35
Preparation and Characterization of Docetaxel-PLGA Nanoparticles Coated with Folic Acid-chitosan Conjugate for Cancer Treatment	34
Inhibition of N-Nitrosamine Formation in Drug Products: A Model Study	34
Protein-Polydimethylsiloxane Particles in Liquid Vial Monoclonal Antibody Formulations Containing Poloxamer 188	33
Correlation of Body Weight and Composition With Hepatic Activities of Cytochrome P450 Enzymes	32
A Fully Integrated Online Platform For Real Time Monitoring Of Multiple Product Quality Attributes In Biopharmaceutical Processes For Monoclonal Antibody Therapeutics	32
Curcumin Loaded Chitosan-Protamine Nanoparticles Revealed Antitumor Activity Via Suppression of NF-κB, Proinflammatory Cytokines and Bcl-2 Gene Expression in the Breast Cancer Cells	32
Current State and Future Expectations of Translational Modeling Strategies to Support Drug Product Development, Manufacturing Changes and Controls: A Workshop Summary Report	32
Identification and Characterization of Polysorbate-Degrading Enzymes in a Monoclonal Antibody Formulation	32
Stability of Freeze-Dried Protein Formulations: Contributions of Ice Nucleation Temperature and Residence Time in the Freeze-Concentrate	32
Curcumin Encapsulated Casein Nanoparticles: Enhanced Bioavailability and Anticancer Efficacy	32
Predicting the Permeability of Macrocycles from Conformational Sampling – Limitations of Molecular Flexibility	31
Coamorphous System of Florfenicol-Oxymatrine for Improving the Solubility and Dissolution Rate of Florfenicol: Preparation, Characterization and Molecular Dynamics Simulation	31
Ongoing Challenges to Develop High Concentration Monoclonal Antibody-based Formulations for Subcutaneous Administration: Quo Vadis?	31
Application of Extrusion-Based 3D Printed Dosage Forms in the Treatment of Chronic Diseases	30
Human Serum Albumin as Multifunctional Nanocarrier for Cancer Therapy	30
Formulation of Chitosan Stabilized Silver Nanoparticle-Containing Wound Healing Film: In Vitro and In Vivo Characterization	29
Warp-Speed Covid-19 Vaccine Development: Beneficiaries of Maturation in Biopharmaceutical Technologies and Public-Private Partnerships	29
Whole-Body Pharmacokinetics of Antibody in Mice Determined using Enzyme-Linked Immunosorbent Assay and Derivation of Tissue Interstitial Concentrations	29
Applications of Physiologically Based Biopharmaceutics Modeling (PBBM) to Support Drug Product Quality: A Workshop Summary Report	29
Impact of Hypromellose Acetate Succinate Grade on Drug Amorphous Solubility and In Vitro Membrane Transport	29
The Landscape of Potential Small and Drug Substance Related Nitrosamines in Pharmaceuticals	29
Cubosomes as a Potential Oral Drug Delivery System for Enhancing the Hepatoprotective Effect of Coenzyme Q10	28
A Nitrite Excipient Database: A Useful Tool to Support N-Nitrosamine Risk Assessments for Drug Products	28
Industry Perspective on the use and Characterization of Polysorbates for Biopharmaceutical Products Part 1: Survey Report on Current State and Common Practices for Handling and Control of Polysorbates	28
Processability of poly(vinyl alcohol) Based Filaments With Paracetamol Prepared by Hot-Melt Extrusion for Additive Manufacturing	27
Design and Investigation of Penetrating Mechanism of Octaarginine-Modified Alginate Nanoparticles for Improving Intestinal Insulin Delivery	27
Investigation of the Pristine and Functionalized Carbon Nanotubes as a Delivery System for the Anticancer Drug Dacarbazine: Drug Encapsulation	27
Polysorbate Degradation and Particle Formation in a High Concentration mAb: Formulation Strategies to Minimize Effect of Enzymatic Polysorbate Degradation	27
Formulation Development, In Vitro and In Vivo Evaluation of Topical Hydrogel Formulation of Econazole Nitrate-Loaded β-Cyclodextrin Nanosponges	27
Establishing the Bioequivalence Safe Space for Immediate-Release Oral Dosage Forms using Physiologically Based Biopharmaceutics Modeling (PBBM): Case Studies	27
The Effects of Solid and Liquid Lipids on the Physicochemical Properties of Nanostructured Lipid Carriers	26
Mitochondrial Delivery of an Anticancer Drug Via Systemic Administration Using a Mitochondrial Delivery System That Inhibits the Growth of Drug-Resistant Cancer Engrafted on Mice	26
Physical Stability and Dissolution of Lumefantrine Amorphous Solid Dispersions Produced by Spray Anti-Solvent Precipitation	26
Lego-Inspired Capsular Devices for the Development of Personalized Dietary Supplements: Proof of Concept With Multimodal Release of Caffeine	26
In-Use Interfacial Stability of Monoclonal Antibody Formulations Diluted in Saline i.v. Bags	25
Intramacrophage Delivery of Dual Drug Loaded Nanoparticles for Effective Clearance of Mycobacterium tuberculosis	25
Contemporary Formulation Development for Inhaled Pharmaceuticals	25
Machine Learning Feature Selection for Predicting High Concentration Therapeutic Antibody Aggregation	25
3D Printed Intragastric Floating and Sustained-Release Tablets with Air Chambers	24
Exploration and Preparation of Patient-specific Ciprofloxacin Implants Drug Delivery System Via 3D Printing Technologies	24
Improved Bioavailability with Dry Powder Cannabidiol Inhalation: A Phase 1 Clinical Study	24
Comprehensive Development in Organ-On-A-Chip Technology	24

Applications of Machine Learning in Solid Oral Dosage Form Development	24
Nanoemulsion for Improving the Oral Bioavailability of Hesperetin: Formulation Optimization and Absorption Mechanism	24
Antipsychotic Potential and Safety Profile of TPGS-Based Mucoadhesive Aripiprazole Nanoemulsion: Development and Optimization for Nose-To-Brain Delivery	23
Degradation of Polysorbate 20 by Sialate O-Acetylesterase in Monoclonal Antibody Formulations	23
In Silico Models of Human PK Parameters. Prediction of Volume of Distribution Using an Extensive Data Set and a Reduced Number of Parameters	23
Fabrication of Rapidly Separable Microneedles for Transdermal Delivery of Metformin on Diabetic Rats	23
Dissolution and Permeability Properties of Co-Amorphous Formulations of Hydrochlorothiazide	22
Molecular Dynamics Simulation to Uncover the Mechanisms of Protein Instability During Freezing	22
Designing, Optimization and Characterization of Trifluralin Transfersomal Gel to Passively Target Cutaneous Leishmaniasis	22
Evaluation of Super Refined™ Polysorbate 20 With Respect to Polysorbate Degradation, Particle Formation and Protein Stability	22
Physiologically Based Biopharmaceutics Modeling to Demonstrate Virtual Bioequivalence and Bioequivalence Safe-space for Ribociclib which has Permeation Rate-controlled Absorption	22
Overview of Humira® Biosimilars: Current European Landscape and Future Implications	22
99mTc-Methionine Gold Nanoparticles as a Promising Biomaterial for Enhanced Tumor Imaging	22
Surface-Induced Protein Aggregation and Particle Formation in Biologics: Current Understanding of Mechanisms, Detection and Mitigation Strategies	22
Current Approaches of Preservation of Cells During (freeze-) Drying	22
Automated, High-Throughput Infrared Spectroscopy for Secondary Structure Analysis of Protein Biopharmaceuticals	22
Advanced Characterization of Silicone Oil Droplets in Protein Therapeutics Using Artificial Intelligence Analysis of Imaging Flow Cytometry Data	22
Impact of mAb Aggregation on Its Biological Activity: Rituximab as a Case Study	22
Best Practices in the Development and Validation of Physiologically Based Biopharmaceutics Modeling. A Workshop Summary Report	21
Cyrene™ as an Alternative Sustainable Solvent for the Preparation of Poly(lactic-co-glycolic acid) Nanoparticles	21
Putative Phospholipase B-Like 2 is Not Responsible for Polysorbate Degradation in Monoclonal Antibody Drug Products	21
Prediction of Total Drug Clearance in Humans Using Animal Data: Proposal of a Multimodal Learning Method Based on Deep Learning	21
Characterization of Polysorbate 80 by Liquid Chromatography-Mass Spectrometry to Understand Its Susceptibility to Degradation and Its Oxidative Degradation Pathway	21
Fabrication of All-Trans Retinoic Acid loaded Chitosan/Tripolyphosphate Lipid Hybrid Nanoparticles as a Novel Oral Delivery Approach for Management of Diabetic Nephropathy in Rats	21
Proteins on the Rack: Mechanistic Studies on Protein Particle Formation During Peristaltic Pumping	20
Prediction Machines: Applied Machine Learning for Therapeutic Protein Design and Development	20
Glass Leachables as a Nucleation Factor for Free Fatty Acid Particle Formation in Biopharmaceutical Formulations	20
A Review on High Pressure Experiments for Study of Crystallographic Behavior and Polymorphism of Pharmaceutical Materials	20
Amelioration of Tumor Targeting and In Vivo Biodistribution of 99mTc-Methotrexate-Gold Nanoparticles (99mTc-Mex-AuNPs)	20
Novel Polyvinyl Pyrrolidone–Loaded Olopatadine HCl–Laden Doughnut Contact Lens to Treat Allergic Conjunctivitis	20
Stabilizing Polysorbate 20 and 80 Against Oxidative Degradation	20
Industry Perspective on the Use and Characterization of Polysorbates for Biopharmaceutical Products Part 2: Survey Report on Control Strategy Preparing for the Future	20
In Vitro Biopredictive Methods: A Workshop Summary Report	19
Improvement of Oral Bioavailability and Anti-Tumor Effect of Zingerone Self-Microemulsion Drug Delivery System	19
Simultaneous Monitoring and Comparison of Multiple Product Quality Attributes for Cell Culture Processes at Different Scales Using a LC/MS/MS Based Multi-Attribute Method	19
A Retrospective Biopharmaceutical Analysis of >800 Approved Oral Drug Products: Are Drug Properties of Solid Dispersions and Lipid-Based Formulations Distinctive?	19
Tolerability of risk: A commentary on the nitrosamine contamination issue	19
In Vitro and In Vivo Evaluation of 3D Printed Capsules with Pressure Triggered Release Mechanism for Oral Peptide Delivery	19
Green Synthesis of Ciprofloxacin-Loaded Cerium Oxide/Chitosan Nanocarrier and its Activity Against MRSA-Induced Mastitis	19
Easy to Swallow “Instant” Jelly Formulations for Sustained Release Gliclazide Delivery	19
Release Mechanisms of Amorphous Solid Dispersions: Role of Drug-Polymer Phase Separation and Morphology	18
Impact of Changes in Free Concentrations and Drug-Protein Binding on Drug Dosing Regimens in Special Populations and Disease States	18
The Complexity of the Blood-Brain Barrier and the Concept of Age-Related Brain Targeting: Challenges and Potential of Novel Solid Lipid-Based Formulations	18
Impact of Polysorbate 80 Grade on the Interfacial Properties and Interfacial Stress Induced Subvisible Particle Formation in Monoclonal Antibodies	18
An Industry Perspective on Compatibility Assessment of Closed System Drug-Transfer Devices for Biologics	18
Characterization of Spray Dried Particles Through Microstructural Imaging	18
Blood-Brain Barrier Permeability of Asiaticoside, Madecassoside and Asiatic Acid in Porcine Brain Endothelial Cell Model	18
Quantitative Differentiation of Protein Aggregates From Other Subvisible Particles in Viscous Mixtures Through Holographic Characterization	18
Safety and Pharmacokinetic Assessments of a Novel Ivermectin Nasal Spray Formulation in a Pig Model	18
Cationic Polymeric Nanoparticles for Improved Ocular Delivery and Antimycotic Activity of Terconazole	17
Voriconazole Ternary Micellar Systems for the Treatment of Ocular Mycosis: Statistical Optimization and In Vivo Evaluation	17
Physically Optimized Nano-Lipid Carriers Augment Raloxifene and Vitamin D Oral Bioavailability in Healthy Humans for Management of Osteoporosis	17
Novel Thermosensitive Polymer-Modified Liposomes as Nano-Carrier of Hydrophobic Antitumor Drugs	17
Application of Thermodynamic Phase Diagrams and Gibbs Free Energy of Mixing for Screening of Polymers for Their Use in Amorphous Solid Dispersion Formulation of a Non-Glass-Forming Drug	17
Micelle Driven Oxidation Mechansim and Novel Oxidation Markers for Different Grades of Polysorbate 20 and 80	17
Development, Optimization, and Antifungal Assessment of Ocular Gel Loaded With Ketoconazole Cubic Liquid Crystalline Nanoparticles	17
Amelioration of Endotoxin-Induced Uveitis in Rabbit by Topical Administration of Tacrolimus Proglycosome Nano-Vesicles	16
Molecular Dynamics Simulations Reveal Membrane Interactions for Poorly Water-Soluble Drugs: Impact of Bile Solubilization and Drug Aggregation	16
Evaluation of Cytotoxicity of Self-Emulsifying Formulations Containing Long-Chain Lipids Using Caco-2 Cell Model: Superior Safety Profile Compared to Medium-Chain Lipids	16
The Drug Release Kinetics and Anticancer Activity of the GO/PVA-Curcumin Nanostructures: The Effects of the Preparation Method and the GO Amount	16
A Drug–Drug Cocrystal of Dihydromyricetin and Pentoxifylline	16
In Situ Hexosomal Gel as a Promising Tool to Ameliorate the Transnasal Brain Delivery of Vinpocetine: Central Composite Optimization and In Vivo Biodistribution	16
Cereal-Based 3D Printed Dosage Forms for Drug Administration During Breakfast in Pediatric Patients within a Hospital Setting	16
Ritonavir Form III: A New Polymorph After 24 Years	16
Evaluation of In Vivo toxicity of Novel Biosurfactant from Candida parapsilosis loaded in PLA-PEG Polymeric Nanoparticles	16
Bone-Targeted Calcium Phosphate-Polymer Hybrid Nanoparticle Co-Deliver Zoledronate and Docetaxel to Treat Bone Metastasis of Prostate Cancer	16
Plasma and Red Blood Cell Membrane Accretion and Pharmacokinetics of RT001 (bis-Allylic 11,11-D2-Linoleic Acid Ethyl Ester) during Long Term Dosing in Patients	16
Intradermal Administration of Influenza Vaccine with Trehalose and Pullulan-Based Dissolving Microneedle Arrays	16
Dexamethasone Sodium Phosphate Loaded Modified Cyclodextrin Based Nanoparticles: An Efficient Treatment for Rheumatoid Arthritis	16
Suitability of the z-Factor for Dissolution Simulation of Solid Oral Dosage Forms: Potential Pitfalls and Refinements	16
Re-Envisioning Pharmaceutical Manufacturing: Increasing Agility for Global Patient Access	16
Amorphous Solid Dispersions of Felodipine and Nifedipine with Soluplus®: Drug-Polymer Miscibility and Intermolecular Interactions	15
Antivirals and the Potential Benefits of Orally Inhaled Drug Administration in COVID-19 Treatment	15
Novel Insights to Enhance Therapeutics With Acyclovir in the Management of Herpes Simplex Encephalitis	15
Emerging Challenges and Innovations in Surfactant-mediated Stabilization of Biologic Formulations	15
Caffeine as a Viscosity Reducer for Highly Concentrated Monoclonal Antibody Solutions	15
Drug Metabolites Potently Inhibit Renal Organic Anion Transporters, OAT1 and OAT3	15
Pregnancy-Related Hormones Increase Nifedipine Metabolism in Human Hepatocytes by Inducing CYP3A4 Expression	15
Mechanistic Models for USP2 Dissolution Apparatus, Including Fluid Hydrodynamics and Sedimentation	15
Characterization of Orodispersible Films: An Overview of Methods and Introduction to a New Disintegration Test Apparatus Using LDR - LED Sensors	15

Doxorubicin-loaded, pH-sensitive Albumin Nanoparticles for Lung Cancer Cell Targeting	15
The Role of Self-Nanoemulsifying Drug Delivery Systems of CDODA-Me in Sensitizing Erlotinib-Resistant Non–Small Cell Lung Cancer	15
Improved Solubility and Oral Absorption of Emodin-Nicotinamide Cocrystal Over Emodin with PVP as a Solubility Enhancer and Crystallization Inhibitor	15
Regulatory Experiences with Root Causes and Risk Factors for Nitrosamine Impurities in Pharmaceuticals	15
Lactosome-Conjugated siRNA Nanoparticles for Photo-Enhanced Gene Silencing in Cancer Cells	14
Delivery of TSPAN1 siRNA by Novel Th17 Targeted Cationic Liposomes for Gastric Cancer Intervention	14
Population Pharmacokinetics and Dosing Recommendations of Levetiracetam in Adult and Elderly Patients With Epilepsy	14
Aqueous Dissolution and Dispersion Behavior of Polyvinylpyrrolidone Vinyl Acetate-based Amorphous Solid Dispersion of Ritonavir Prepared by Hot-Melt Extrusion with and without Added Surfactants	14
Near UV and Visible Light Photo-Degradation Mechanisms in Citrate Buffer: One-Electron Reduction of Peptide and Protein Disulfides promotes Oxidation and Cis/Trans Isomerization of Unsaturated Fatty A	14
Pharmacokinetic and Pharmacodynamic Evaluation of Gemifloxacin Chitosan Nanoparticles As an Antibacterial Ocular Dosage Form	14
The Impact of Product and Process Related Critical Quality Attributes on Immunogenicity and Adverse Immunological Effects of Biotherapeutics	14
Elucidation of Colloid Performances of Thermosensitive In Situ–Forming Ophthalmic Gel Formed by Poloxamer 407 for Loading Drugs	14
Comparison of Different Chitosan Lipid Nanoparticles for Improved Ophthalmic Tetrandrine Delivery: Formulation, Characterization, Pharmacokinetic and Molecular Dynamics Simulation	14
Moesin-Mediated P-Glycoprotein Activation During Snail-Induced Epithelial-Mesenchymal Transition in Lung Cancer Cells	14
Stress Factors in Primary Packaging, Transportation and Handling of Protein Drug Products and Their Impact on Product Quality	14
A composite System Combining Self-Targeted Carbon Dots and Thermosensitive Hydrogels for Challenging Ocular Drug Delivery	14
Biorelevant Two-Stage In Vitro Testing for rDCS Classification and in PBPK Modeling–Case Example Ritonavir	14
Effects of Linkers on the Development of Liposomal Formulation of Cholesterol Conjugated Cobalt Bis(dicarbollides)	14
Modulation of Epidermal Growth Factor Release by Biopolymer-Coated Liposomes	14
Surface Modification of Mobile Composition of Matter (MCM)-41 Type Silica Nanoparticles for Potential Oral Mucosa Vaccine Delivery	14
Synergistic Computational Modeling Approaches as Team Players in the Game of Solubility Predictions	14
Mannitol as an Excipient for Lyophilized Injectable Formulations	14
N-Nitrosamine Formation in Pharmaceutical Solid Drug Products: Experimental Observations	14
Comparison of Strategies in Development and Manufacturing of Low Viscosity, Ultra-High Concentration Formulation for IgG1 Antibody	14
A Fast and Non-destructive Terahertz Dissolution Assay for Immediate Release Tablets	14
3D Printing and Dissolution Testing of Novel Capsule Shells for Use in Delivering Acetaminophen	14
Quantitation of Trace Levels of DNA Released from Disrupted Adeno-Associated Virus Gene Therapy Vectors	14
In Vitro and In Vivo Studies of Polyvinyl Pyrrolidone–Coated Sparfloxacin-Loaded Ring Contact Lens to Treat Conjunctivitis	14
Particles in Biopharmaceutical Formulations, Part 2: An Update on Analytical Techniques and Applications for Therapeutic Proteins, Viruses, Vaccines and Cells	14
The Impact of Formulation Composition and Process Settings of Traditional Batch Versus Continuous Freeze-Drying On Protein Aggregation	14
Disintegrant Selection in Hydrophobic Tablet Formulations	14
CFD-DEM -DDM Model for Spray Coating Process in a Wurster Coater	14
Functionalized Graphene Oxide as Drug Delivery Systems for Platinum Anticancer Drugs	14
Effect of Linker-Drug Properties and Conjugation Site on the Physical Stability of ADCs	13
Carboplatin Niosomal Nanoplatform for Potentiated Chemotherapy	13
Formulation and In-Vitro Characterisation of Cross-Linked Amphiphilic Guar Gum Nanocarriers for Percutaneous Delivery of Arbutin	13
Systemic Inflammation Induced Changes in Protein Expression of ABC Transporters and Ionotropic Glutamate Receptor Subunit 1 in the Cerebral Cortex of Familial Alzheimer`s Disease Mouse Model	13
Diffusion Modeling and In Vitro Release Kinetics Studies of Curcumin−Loaded Superparamagnetic Nanomicelles in Cancer Drug Delivery System	13
Development of Gene Therapy Vectors: Remaining Challenges	13
Aerosol Inhalation Delivery of Triazavirin in Mice: Outlooks for Advanced Therapy Against Novel Viral Infections	13
Characterization of Brain-Targeted Drug Delivery Enhanced by a Combination of Lipid-Based Microbubbles and Non-Focused Ultrasound	13
Strategies for Setting Patient-Centric Commercial Specifications for Biotherapeutic Products	13
Comprehensive Ocular and Systemic Pharmacokinetics of Brinzolamide in Rabbits After Intracameral, Topical, and Intravenous Administration	13
Tabletability Flip – Role of Bonding Area and Bonding Strength Interplay	13
Eutectics and Salt of Dapsone With Hydroxybenzoic Acids: Binary Phase Diagrams, Characterization and Evaluation	13
Effect of Conjugation Site and Technique on the Stability and Pharmacokinetics of Antibody-Drug Conjugates	13
A Magnetic T7 Peptide&AS1411 Aptamer-Modified Microemulsion for Triple Glioma-Targeted Delivery of Shikonin and Docetaxel	13
Machine Learning and Accelerated Stress Approaches to Differentiate Potential Causes of Aggregation in Polyclonal Antibody Formulations During Shipping	13
Trouble With the Neighbor During Freeze-Drying: Rivalry About Energy	13
Structural Requirements for Uptake of Diphenhydramine Analogs into hCMEC/D3 Cells Via the Proton-Coupled Organic Cation Antiporter	13
Transdermal Route: A Viable Option for Systemic Delivery of Antidepressants	13
Systems and Clinical Pharmacology of COVID-19 Therapeutic Candidates: A Clinical and Translational Medicine Perspective	13
Ultrasensitive Quantification of Drug-metabolizing Enzymes and Transporters in Small Sample Volume by Microflow LC-MS/MS	13
Composing Novel Diclofenac Potassium and l-Proline Salt Cocrystal as a Strategy to Increase Solubility and Dissolution	13
Dissolution/Permeation of Albendazole in the Presence of Cyclodextrin and Bile Salts: A Mechanistic In Vitro Study into Factors Governing Oral Bioavailability	13
Rapid Developability Assessments to Formulate Recombinant Protein Antigens as Stable, Low-Cost, Multi-Dose Vaccine Candidates: Case-Study With Non-Replicating Rotavirus (NRRV) Vaccine Antigens	13
Application of First Principles Primary Drying Model to Lyophilization Process Design and Transfer: Case Studies From the Industry	13
Evaluation of the Drug Release Kinetics in Assembled Modular Systems Based on the Dome Matrix Technology	13
Resveratrol-Loaded Vesicular Elastic Nanocarriers Gel in Imiquimod-Induced Psoriasis Treatment: In Vitro and In Vivo Evaluation	13
Extended Characterization and Impact of Visible Fatty Acid Particles - A Case Study With a mAb Product	13
Application of PC-SAFT EOS for Pharmaceuticals: Solubility, Co-Crystal, and Thermodynamic Modeling	13
Reconstitution Time for Highly Concentrated Lyophilized Proteins: Role of Formulation and Protein	13
Probing Microenvironmental Acidity in Lyophilized Protein and Vaccine Formulations Using Solid-state NMR Spectroscopy	13
Evaluation of Prediction Accuracy for Volume of Distribution in Rat and Human Using In Vitro, In Vivo, PBPK and QSAR Methods	13
Determination of Holdup Volume and Transient Contact Compatibility of Closed System Transfer Devices for a Reconstituted Lyophilized Drug Product	13
Effects of Transportation of IV Bags Containing Protein Formulations Via Hospital Pneumatic Tube System: Particle Characterization by Multiple Methods	13
Stress and Deformation of Optimally Shaped Silicon Microneedles for Transdermal Drug Delivery	13
Challenges for Cell-Based Medicinal Products From a Pharmaceutical Product Perspective	13
Prediction of Human Pharmacokinetics and Clinical Effective Dose of SI–B001, an EGFR/HER3 Bi-specific Monoclonal Antibody	13
Influence of Protein Adsorption on Aggregation in Prefilled Syringes	12
Transport Alteration of 4-Phenyl Butyric Acid Mediated by a Sodium- and Proton-Coupled Monocarboxylic Acid Transporter System in ALS Model Cell Lines (NSC-34) Under Inflammatory States	12
A Rapid, Small-Volume Approach to Evaluate Protein Aggregation at Air-Water Interfaces	12
Understanding the Impact of Multi-factorial Composition on Efficient Loading of the Stable Ketoprofen Nanoparticles on Orodispersible Films Using Box-Behnken Design	12
Determination of Protein-Protein Interactions at High Co-Solvent Concentrations Using Static and Dynamic Light Scattering	12
Stress Factors in Protein Drug Product Manufacturing and Their Impact on Product Quality	12
In situ Formed Implants, Based on PLGA and Eudragit Blends, for Novel Florfenicol Controlled Release Formulations	12
Lysine-Based Biodegradable Surfactants: Increasing the Lipophilicity of Insulin by Hydrophobic Ion Paring	12
Integration of Computational and Experimental Approaches to Elucidate Mechanisms of First-Pass Lymphatic Drug Sequestration and Long-Acting Pharmacokinetics of the Injectable Triple-HIV Drug Combinati	12
Uptake Kinetics Of Liposomal Formulations of Differing Charge Influences Development of in Vivo Dendritic Cell Immunotherapy	12
Transferrin-Modified Nanoliposome Codelivery Strategies for Enhancing the Cancer Therapy	12
A Highly Sensitive LC-MS/MS Method for Targeted Quantitation of Lipase Host Cell Proteins in Biotherapeutics	12
Impact of Surfactants on the Functionality of Prefilled Syringes	12
Improvement of New Dianionic Ionic Liquids vs Monoanionic in Solubility of Poorly Water-Soluble Drugs	12
The Confluence of Innovation in Therapeutics and Regulation: Recent CMC Considerations	12
Continuous Manufacturing of Ketoprofen Delayed Release Pellets Using Melt Extrusion Technology: Application of QbD Design Space, Inline Near Infrared, and Inline Pellet Size Analysis	12
Considerations in the Development of Physically Stable High Drug Load API- Polymer Amorphous Solid Dispersions in the Glassy State	12
Transport and Lymphatic Uptake of Biotherapeutics Through Subcutaneous Injection	12
Relationship Between Phase Solubility Diagrams and Crystalline Structures During Dissolution of Cimetidine/Cyclodextrin Complex Crystals	12
Characterization of Photodegradation Products of Bepotastine Besilate and In Silico Evaluation of Their Physicochemical, Absorption, Distribution, Metabolism, Excretion and Toxicity Properties	12
Development of Lecithin/Chitosan Nanoparticles for Promoting Topical Delivery of Propranolol Hydrochloride: Design, Optimization and In-Vivo Evaluation	12
Intra-Articular Dual Drug Delivery for Synergistic Rheumatoid Arthritis Treatment	12
Addressing Patient to Patient Variability for Autologous CAR T Therapies	12
Managing the Impact of Immunogenicity in an Era of Immunotherapy: From Bench to Bedside	12
Lamination of Pharmaceutical Tablets: Classification and Influence of Process Parameters	12
The Amorphous Quercetin/ Hydroxypropylmethylcellulose Acetate Succinate Solid Dispersions Prepared by Co-Precipitation Method to Enhance Quercetin Dissolution	12